Results

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AFA results for: TSA1-e07.ls

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Gene Set Collection: KEGG

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
KEGG 03040 View Gene Set 6.754e-13 128 1.172e-10 1 Spliceosome www.genome.jp/d...
KEGG 04110 View Gene Set 1.095e-12 128 1.172e-10 1 Cell cycle www.genome.jp/d...
KEGG 04120 View Gene Set 1.471e-08 139 1.049e-06 3 Ubiquitin mediated proteolysis www.genome.jp/d...
KEGG 04114 View Gene Set 8.323e-05 114 0.0038 4 Oocyte meiosis www.genome.jp/d...
KEGG 04115 View Gene Set 8.878e-05 69 0.0038 4 p53 signaling pathway www.genome.jp/d...
KEGG 03018 View Gene Set 0.0001527 59 0.005445 6 RNA degradation www.genome.jp/d...
KEGG 04914 View Gene Set 0.0005123 87 0.01566 7 Progesterone-mediated oocyte maturation www.genome.jp/d...
KEGG 03030 View Gene Set 0.0006186 36 0.01655 8 DNA replication www.genome.jp/d...
KEGG 00100 View Gene Set 0.0009899 17 0.02354 9 Steroid biosynthesis www.genome.jp/d...
KEGG 00240 View Gene Set 0.001491 99 0.0319 10 Pyrimidine metabolism www.genome.jp/d...
KEGG 00562 View Gene Set 0.001701 57 0.0331 11 Inositol phosphate metabolism www.genome.jp/d...
KEGG 04710 View Gene Set 0.002092 23 0.03731 12 Circadian rhythm - mammal www.genome.jp/d...
KEGG 03410 View Gene Set 0.002567 34 0.04226 13 Base excision repair www.genome.jp/d...

Gene Set Collection: GO

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
GO GO:0005622 View Gene Set 8.693e-99 11329 1.161e-94 1 intracellular amigo.geneontol...
GO GO:0044424 View Gene Set 1.087e-94 10976 7.258e-91 2 intracellular part amigo.geneontol...
GO GO:0043227 View Gene Set 4.662e-91 8383 2.076e-87 3 membrane-bounded organelle amigo.geneontol...
GO GO:0043231 View Gene Set 1.191e-90 8376 3.979e-87 4 intracellular membrane-bounded organelle amigo.geneontol...
GO GO:0043229 View Gene Set 1.918e-80 9346 5.125e-77 5 intracellular organelle amigo.geneontol...
GO GO:0043226 View Gene Set 1.151e-79 9360 2.564e-76 6 organelle amigo.geneontol...
GO GO:0005634 View Gene Set 1.51e-78 5198 2.882e-75 7 nucleus amigo.geneontol...
GO GO:0044428 View Gene Set 1.249e-72 1938 2.086e-69 8 nuclear part amigo.geneontol...
GO GO:0031981 View Gene Set 1.105e-59 1518 1.64e-56 9 nuclear lumen amigo.geneontol...
GO GO:0044260 View Gene Set 7.243e-59 5699 9.676e-56 10 cellular macromolecule metabolic process amigo.geneontol...
GO GO:0070013 View Gene Set 2.258e-57 1845 2.742e-54 11 intracellular organelle lumen amigo.geneontol...
GO GO:0044422 View Gene Set 1.874e-56 5089 2.086e-53 12 organelle part amigo.geneontol...
GO GO:0044446 View Gene Set 2.041e-56 5019 2.097e-53 13 intracellular organelle part amigo.geneontol...
GO GO:0043233 View Gene Set 9.431e-54 1881 9e-51 14 organelle lumen amigo.geneontol...
GO GO:0031974 View Gene Set 2.502e-52 1917 2.228e-49 15 membrane-enclosed lumen amigo.geneontol...
GO GO:0044237 View Gene Set 9.89e-48 7431 8.258e-45 16 cellular metabolic process amigo.geneontol...
GO GO:0090304 View Gene Set 6.061e-46 3724 4.763e-43 17 nucleic acid metabolic process amigo.geneontol...
GO GO:0043170 View Gene Set 1.279e-43 6274 9.49e-41 18 macromolecule metabolic process amigo.geneontol...
GO GO:0006139 View Gene Set 3.429e-40 4294 2.411e-37 19 nucleobase nucleoside nucleotide and nucleic acid metabolic process amigo.geneontol...
GO GO:0005654 View Gene Set 4.563e-39 939 3.048e-36 20 nucleoplasm amigo.geneontol...
GO GO:0007049 View Gene Set 1.192e-36 1006 7.58e-34 21 cell cycle amigo.geneontol...
GO GO:0010467 View Gene Set 5.668e-36 3806 3.442e-33 22 gene expression amigo.geneontol...
GO GO:0005737 View Gene Set 2.356e-35 7676 1.369e-32 23 cytoplasm amigo.geneontol...
GO GO:0044238 View Gene Set 3.568e-35 7629 1.986e-32 24 primary metabolic process amigo.geneontol...
GO GO:0034641 View Gene Set 5.136e-35 4584 2.744e-32 25 cellular nitrogen compound metabolic process amigo.geneontol...
GO GO:0006807 View Gene Set 2.352e-33 4698 1.209e-30 26 nitrogen compound metabolic process amigo.geneontol...
GO GO:0008152 View Gene Set 3.391e-33 8439 1.678e-30 27 metabolic process amigo.geneontol...
GO GO:0005515 View Gene Set 7.589e-32 8146 3.621e-29 28 protein binding amigo.geneontol...
GO GO:0034645 View Gene Set 9.76e-29 3529 4.496e-26 29 cellular macromolecule biosynthetic process amigo.geneontol...
GO GO:0009059 View Gene Set 2.432e-27 3597 1.083e-24 30 macromolecule biosynthetic process amigo.geneontol...
GO GO:0005730 View Gene Set 4.88e-27 734 2.103e-24 31 nucleolus amigo.geneontol...
GO GO:0016070 View Gene Set 1.641e-26 2596 6.852e-24 32 RNA metabolic process amigo.geneontol...
GO GO:0060255 View Gene Set 3.254e-26 3411 1.318e-23 33 regulation of macromolecule metabolic process amigo.geneontol...
GO GO:0003676 View Gene Set 7.881e-26 2979 3.097e-23 34 nucleic acid binding amigo.geneontol...
GO GO:0044464 View Gene Set 1.249e-25 15066 4.766e-23 35 cell part amigo.geneontol...
GO GO:0005623 View Gene Set 1.313e-25 15067 4.874e-23 36 cell amigo.geneontol...
GO GO:0000278 View Gene Set 4.243e-25 489 1.532e-22 37 mitotic cell cycle amigo.geneontol...
GO GO:0022402 View Gene Set 6.543e-25 676 2.3e-22 38 cell cycle process amigo.geneontol...
GO GO:0006996 View Gene Set 7.992e-24 1501 2.638e-21 39 organelle organization amigo.geneontol...
GO GO:0043228 View Gene Set 8.096e-24 2690 2.638e-21 39 non-membrane-bounded organelle amigo.geneontol...
GO GO:0043232 View Gene Set 8.096e-24 2690 2.638e-21 39 intracellular non-membrane-bounded organelle amigo.geneontol...
GO GO:0009987 View Gene Set 1.499e-23 11620 4.769e-21 42 cellular process amigo.geneontol...
GO GO:0044451 View Gene Set 2.393e-23 600 7.436e-21 43 nucleoplasm part amigo.geneontol...
GO GO:0010468 View Gene Set 6.494e-23 2958 1.972e-20 44 regulation of gene expression amigo.geneontol...
GO GO:0006396 View Gene Set 9.743e-23 578 2.893e-20 45 RNA processing amigo.geneontol...
GO GO:0010556 View Gene Set 1.268e-22 2901 3.681e-20 46 regulation of macromolecule biosynthetic process amigo.geneontol...
GO GO:0022403 View Gene Set 4.59e-22 522 1.305e-19 47 cell cycle phase amigo.geneontol...
GO GO:0009058 View Gene Set 7.981e-21 4436 2.221e-18 48 biosynthetic process amigo.geneontol...
GO GO:0019222 View Gene Set 9.379e-21 4060 2.557e-18 49 regulation of metabolic process amigo.geneontol...
GO GO:0044249 View Gene Set 1.366e-20 4326 3.65e-18 50 cellular biosynthetic process amigo.geneontol...
GO GO:0080090 View Gene Set 1.437e-20 3585 3.765e-18 51 regulation of primary metabolic process amigo.geneontol...
GO GO:0000279 View Gene Set 2.082e-20 406 5.35e-18 52 M phase amigo.geneontol...
GO GO:0031323 View Gene Set 4.034e-20 3768 1.017e-17 53 regulation of cellular metabolic process amigo.geneontol...
GO GO:0006350 View Gene Set 5.017e-20 2744 1.241e-17 54 transcription amigo.geneontol...
GO GO:0048285 View Gene Set 1.187e-19 286 2.883e-17 55 organelle fission amigo.geneontol...
GO GO:0044267 View Gene Set 1.917e-19 2465 4.573e-17 56 cellular protein metabolic process amigo.geneontol...
GO GO:0005488 View Gene Set 1.953e-19 12334 4.578e-17 57 binding amigo.geneontol...
GO GO:0000087 View Gene Set 4.317e-19 286 9.943e-17 58 M phase of mitotic cell cycle amigo.geneontol...
GO GO:0000280 View Gene Set 6.843e-19 276 1.524e-16 59 nuclear division amigo.geneontol...
GO GO:0007067 View Gene Set 6.843e-19 276 1.524e-16 59 mitosis amigo.geneontol...
GO GO:0016071 View Gene Set 7.339e-19 381 1.607e-16 61 mRNA metabolic process amigo.geneontol...
GO GO:0008380 View Gene Set 2.631e-18 300 5.67e-16 62 RNA splicing amigo.geneontol...
GO GO:0016043 View Gene Set 6.925e-18 2937 1.469e-15 63 cellular component organization amigo.geneontol...
GO GO:0045449 View Gene Set 2.075e-17 2647 4.331e-15 64 regulation of transcription amigo.geneontol...
GO GO:0003723 View Gene Set 3.1e-17 732 6.371e-15 65 RNA binding amigo.geneontol...
GO GO:0009889 View Gene Set 3.943e-17 3070 7.863e-15 66 regulation of biosynthetic process amigo.geneontol...
GO GO:0051726 View Gene Set 3.89e-17 451 7.863e-15 66 regulation of cell cycle amigo.geneontol...
GO GO:0031326 View Gene Set 6.34e-17 3048 1.246e-14 68 regulation of cellular biosynthetic process amigo.geneontol...
GO GO:0006397 View Gene Set 3.254e-16 317 6.301e-14 69 mRNA processing amigo.geneontol...
GO GO:0000166 View Gene Set 5.073e-16 2257 9.681e-14 70 nucleotide binding amigo.geneontol...
GO GO:0008134 View Gene Set 5.336e-16 525 1.004e-13 71 transcription factor binding amigo.geneontol...
GO GO:0016604 View Gene Set 1.058e-15 198 1.963e-13 72 nuclear body amigo.geneontol...
GO GO:0030528 View Gene Set 1.238e-15 950 2.266e-13 73 transcription regulator activity amigo.geneontol...
GO GO:0015630 View Gene Set 1.494e-15 587 2.698e-13 74 microtubule cytoskeleton amigo.geneontol...
GO GO:0005694 View Gene Set 1.519e-15 507 2.706e-13 75 chromosome amigo.geneontol...
GO GO:0043412 View Gene Set 4.222e-15 1848 7.345e-13 76 macromolecule modification amigo.geneontol...
GO GO:0003712 View Gene Set 4.233e-15 364 7.345e-13 76 transcription cofactor activity amigo.geneontol...
GO GO:0051301 View Gene Set 5.62e-15 358 9.626e-13 78 cell division amigo.geneontol...
GO GO:0006464 View Gene Set 9.468e-15 1768 1.601e-12 79 protein modification process amigo.geneontol...
GO GO:0050794 View Gene Set 2.19e-14 6236 3.658e-12 80 regulation of cellular process amigo.geneontol...
GO GO:0019219 View Gene Set 2.88e-14 3040 4.692e-12 81 regulation of nucleobase nucleoside nucleotide and nucleic acid metabolic process amigo.geneontol...
GO GO:0043687 View Gene Set 2.849e-14 1509 4.692e-12 81 post-translational protein modification amigo.geneontol...
GO GO:0044444 View Gene Set 3.068e-14 5184 4.938e-12 83 cytoplasmic part amigo.geneontol...
GO GO:0051171 View Gene Set 6.009e-14 3066 9.557e-12 84 regulation of nitrogen compound metabolic process amigo.geneontol...
GO GO:0006974 View Gene Set 1.072e-13 412 1.685e-11 85 response to DNA damage stimulus amigo.geneontol...
GO GO:0000775 View Gene Set 3.413e-13 146 5.24e-11 86 chromosome centromeric region amigo.geneontol...
GO GO:0044427 View Gene Set 3.394e-13 420 5.24e-11 86 chromosomal part amigo.geneontol...
GO GO:0005819 View Gene Set 5.692e-13 167 8.642e-11 88 spindle amigo.geneontol...
GO GO:0051276 View Gene Set 1.029e-12 548 1.544e-10 89 chromosome organization amigo.geneontol...
GO GO:0003713 View Gene Set 2.463e-12 215 3.655e-10 90 transcription coactivator activity amigo.geneontol...
GO GO:0050789 View Gene Set 2.72e-12 6579 3.994e-10 91 regulation of biological process amigo.geneontol...
GO GO:0016740 View Gene Set 3.285e-12 1691 4.771e-10 92 transferase activity amigo.geneontol...
GO GO:0033554 View Gene Set 3.33e-12 698 4.783e-10 93 cellular response to stress amigo.geneontol...
GO GO:0016568 View Gene Set 4.796e-12 324 6.817e-10 94 chromatin modification amigo.geneontol...
GO GO:0019941 View Gene Set 5.097e-12 302 7.093e-10 95 modification-dependent protein catabolic process amigo.geneontol...
GO GO:0043632 View Gene Set 5.097e-12 302 7.093e-10 95 modification-dependent macromolecule catabolic process amigo.geneontol...
GO GO:0016874 View Gene Set 5.167e-12 436 7.116e-10 97 ligase activity amigo.geneontol...
GO GO:0006259 View Gene Set 1.667e-11 592 2.273e-09 98 DNA metabolic process amigo.geneontol...
GO GO:0044265 View Gene Set 2.209e-11 479 2.98e-09 99 cellular macromolecule catabolic process amigo.geneontol...
GO GO:0006511 View Gene Set 2.361e-11 296 3.154e-09 100 ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0005739 View Gene Set 2.777e-11 1274 3.673e-09 101 mitochondrion amigo.geneontol...
GO GO:0032991 View Gene Set 5.392e-11 3237 7.062e-09 102 macromolecular complex amigo.geneontol...
GO GO:0010605 View Gene Set 8.663e-11 827 1.124e-08 103 negative regulation of macromolecule metabolic process amigo.geneontol...
GO GO:0005524 View Gene Set 9.081e-11 1480 1.167e-08 104 ATP binding amigo.geneontol...
GO GO:0007059 View Gene Set 1.192e-10 94 1.516e-08 105 chromosome segregation amigo.geneontol...
GO GO:0070647 View Gene Set 1.231e-10 356 1.551e-08 106 protein modification by small protein conjugation or removal amigo.geneontol...
GO GO:0010558 View Gene Set 1.303e-10 611 1.626e-08 107 negative regulation of macromolecule biosynthetic process amigo.geneontol...
GO GO:0046907 View Gene Set 1.703e-10 753 2.106e-08 108 intracellular transport amigo.geneontol...
GO GO:0048523 View Gene Set 1.73e-10 1895 2.12e-08 109 negative regulation of cellular process amigo.geneontol...
GO GO:0003677 View Gene Set 2.394e-10 2028 2.907e-08 110 DNA binding amigo.geneontol...
GO GO:0016607 View Gene Set 2.44e-10 116 2.936e-08 111 nuclear speck amigo.geneontol...
GO GO:0016879 View Gene Set 2.649e-10 273 3.16e-08 112 ligase activity forming carbon-nitrogen bonds amigo.geneontol...
GO GO:0003824 View Gene Set 3.819e-10 5198 4.515e-08 113 catalytic activity amigo.geneontol...
GO GO:0019538 View Gene Set 4.176e-10 2935 4.894e-08 114 protein metabolic process amigo.geneontol...
GO GO:0051246 View Gene Set 4.294e-10 652 4.961e-08 115 regulation of protein metabolic process amigo.geneontol...
GO GO:0032559 View Gene Set 4.308e-10 1503 4.961e-08 115 adenyl ribonucleotide binding amigo.geneontol...
GO GO:0003674 View Gene Set 6.151e-10 15462 7.024e-08 117 molecular_function amigo.geneontol...
GO GO:0032268 View Gene Set 6.559e-10 576 7.401e-08 118 regulation of cellular protein metabolic process amigo.geneontol...
GO GO:0005681 View Gene Set 6.593e-10 135 7.401e-08 118 spliceosomal complex amigo.geneontol...
GO GO:0032774 View Gene Set 9.729e-10 1953 1.083e-07 120 RNA biosynthetic process amigo.geneontol...
GO GO:0006366 View Gene Set 1.115e-09 919 1.231e-07 121 transcription from RNA polymerase II promoter amigo.geneontol...
GO GO:0006325 View Gene Set 1.232e-09 425 1.349e-07 122 chromatin organization amigo.geneontol...
GO GO:0006351 View Gene Set 1.285e-09 1949 1.396e-07 123 transcription DNA-dependent amigo.geneontol...
GO GO:0009892 View Gene Set 1.402e-09 889 1.511e-07 124 negative regulation of metabolic process amigo.geneontol...
GO GO:0031324 View Gene Set 1.756e-09 809 1.877e-07 125 negative regulation of cellular metabolic process amigo.geneontol...
GO GO:0032553 View Gene Set 2.159e-09 1851 2.272e-07 126 ribonucleotide binding amigo.geneontol...
GO GO:0032555 View Gene Set 2.159e-09 1851 2.272e-07 126 purine ribonucleotide binding amigo.geneontol...
GO GO:0016881 View Gene Set 2.365e-09 245 2.469e-07 128 acid-amino acid ligase activity amigo.geneontol...
GO GO:0006281 View Gene Set 2.406e-09 309 2.492e-07 129 DNA repair amigo.geneontol...
GO GO:0051603 View Gene Set 2.665e-09 346 2.739e-07 130 proteolysis involved in cellular protein catabolic process amigo.geneontol...
GO GO:0044257 View Gene Set 3.075e-09 349 3.136e-07 131 cellular protein catabolic process amigo.geneontol...
GO GO:0016563 View Gene Set 3.196e-09 430 3.234e-07 132 transcription activator activity amigo.geneontol...
GO GO:0030529 View Gene Set 3.798e-09 504 3.815e-07 133 ribonucleoprotein complex amigo.geneontol...
GO GO:0009890 View Gene Set 5.029e-09 642 5.014e-07 134 negative regulation of biosynthetic process amigo.geneontol...
GO GO:0032446 View Gene Set 5.45e-09 310 5.394e-07 135 protein modification by small protein conjugation amigo.geneontol...
GO GO:0010608 View Gene Set 6.179e-09 247 6.07e-07 136 posttranscriptional regulation of gene expression amigo.geneontol...
GO GO:0006260 View Gene Set 7.415e-09 239 7.231e-07 137 DNA replication amigo.geneontol...
GO GO:0043234 View Gene Set 8.091e-09 2680 7.833e-07 138 protein complex amigo.geneontol...
GO GO:0000793 View Gene Set 8.381e-09 136 8.056e-07 139 condensed chromosome amigo.geneontol...
GO GO:0005635 View Gene Set 8.773e-09 234 8.372e-07 140 nuclear envelope amigo.geneontol...
GO GO:0030554 View Gene Set 8.896e-09 1584 8.429e-07 141 adenyl nucleotide binding amigo.geneontol...
GO GO:0001883 View Gene Set 9.373e-09 1620 8.819e-07 142 purine nucleoside binding amigo.geneontol...
GO GO:0000226 View Gene Set 1.055e-08 178 9.859e-07 143 microtubule cytoskeleton organization amigo.geneontol...
GO GO:0050657 View Gene Set 1.123e-08 102 1.021e-06 144 nucleic acid transport amigo.geneontol...
GO GO:0050658 View Gene Set 1.123e-08 102 1.021e-06 144 RNA transport amigo.geneontol...
GO GO:0051236 View Gene Set 1.123e-08 102 1.021e-06 144 establishment of RNA localization amigo.geneontol...
GO GO:0019787 View Gene Set 1.111e-08 210 1.021e-06 144 small conjugating protein ligase activity amigo.geneontol...
GO GO:0010629 View Gene Set 1.236e-08 573 1.116e-06 148 negative regulation of gene expression amigo.geneontol...
GO GO:0051028 View Gene Set 1.301e-08 90 1.165e-06 149 mRNA transport amigo.geneontol...
GO GO:0016772 View Gene Set 1.308e-08 895 1.165e-06 149 transferase activity transferring phosphorus-containing groups amigo.geneontol...
GO GO:0006403 View Gene Set 1.334e-08 104 1.181e-06 151 RNA localization amigo.geneontol...
GO GO:0000776 View Gene Set 1.483e-08 92 1.304e-06 152 kinetochore amigo.geneontol...
GO GO:0001882 View Gene Set 1.558e-08 1630 1.361e-06 153 nucleoside binding amigo.geneontol...
GO GO:0031327 View Gene Set 1.765e-08 629 1.531e-06 154 negative regulation of cellular biosynthetic process amigo.geneontol...
GO GO:0016567 View Gene Set 2.139e-08 286 1.843e-06 155 protein ubiquitination amigo.geneontol...
GO GO:0007017 View Gene Set 2.476e-08 281 2.121e-06 156 microtubule-based process amigo.geneontol...
GO GO:0017076 View Gene Set 2.978e-08 1934 2.534e-06 157 purine nucleotide binding amigo.geneontol...
GO GO:0051252 View Gene Set 3.005e-08 1869 2.541e-06 158 regulation of RNA metabolic process amigo.geneontol...
GO GO:0000375 View Gene Set 3.194e-08 106 2.684e-06 159 RNA splicing via transesterification reactions amigo.geneontol...
GO GO:0048519 View Gene Set 3.522e-08 2064 2.941e-06 160 negative regulation of biological process amigo.geneontol...
GO GO:0008270 View Gene Set 4e-08 2009 3.319e-06 161 zinc ion binding amigo.geneontol...
GO GO:0009057 View Gene Set 4.032e-08 570 3.325e-06 162 macromolecule catabolic process amigo.geneontol...
GO GO:0007346 View Gene Set 4.674e-08 174 3.807e-06 163 regulation of mitotic cell cycle amigo.geneontol...
GO GO:0016564 View Gene Set 4.673e-08 342 3.807e-06 163 transcription repressor activity amigo.geneontol...
GO GO:0065007 View Gene Set 5.498e-08 6980 4.451e-06 165 biological regulation amigo.geneontol...
GO GO:0016570 View Gene Set 5.865e-08 162 4.72e-06 166 histone modification amigo.geneontol...
GO GO:0016569 View Gene Set 6.292e-08 165 5.034e-06 167 covalent chromatin modification amigo.geneontol...
GO GO:0000779 View Gene Set 8.144e-08 79 6.476e-06 168 condensed chromosome centromeric region amigo.geneontol...
GO GO:0010604 View Gene Set 1.018e-07 976 8.049e-06 169 positive regulation of macromolecule metabolic process amigo.geneontol...
GO GO:0005815 View Gene Set 1.133e-07 277 8.905e-06 170 microtubule organizing center amigo.geneontol...
GO GO:0006355 View Gene Set 1.15e-07 1820 8.934e-06 171 regulation of transcription DNA-dependent amigo.geneontol...
GO GO:0010564 View Gene Set 1.15e-07 161 8.934e-06 171 regulation of cell cycle process amigo.geneontol...
GO GO:0006261 View Gene Set 1.163e-07 74 8.981e-06 173 DNA-dependent DNA replication amigo.geneontol...
GO GO:0044419 View Gene Set 1.335e-07 343 1.025e-05 174 interspecies interaction between organisms amigo.geneontol...
GO GO:0016481 View Gene Set 1.415e-07 512 1.081e-05 175 negative regulation of transcription amigo.geneontol...
GO GO:0030163 View Gene Set 1.47e-07 398 1.116e-05 176 protein catabolic process amigo.geneontol...
GO GO:0016773 View Gene Set 1.492e-07 708 1.126e-05 177 phosphotransferase activity alcohol group as acceptor amigo.geneontol...
GO GO:0045934 View Gene Set 1.684e-07 574 1.264e-05 178 negative regulation of nucleobase nucleoside nucleotide and nucleic acid metabolic process amigo.geneontol...
GO GO:0015931 View Gene Set 1.765e-07 118 1.317e-05 179 nucleobase nucleoside nucleotide and nucleic acid transport amigo.geneontol...
GO GO:0006357 View Gene Set 2.035e-07 760 1.51e-05 180 regulation of transcription from RNA polymerase II promoter amigo.geneontol...
GO GO:0000075 View Gene Set 2.058e-07 109 1.519e-05 181 cell cycle checkpoint amigo.geneontol...
GO GO:0007051 View Gene Set 2.263e-07 57 1.661e-05 182 spindle organization amigo.geneontol...
GO GO:0031325 View Gene Set 2.569e-07 999 1.876e-05 183 positive regulation of cellular metabolic process amigo.geneontol...
GO GO:0006417 View Gene Set 2.637e-07 151 1.915e-05 184 regulation of translation amigo.geneontol...
GO GO:0032270 View Gene Set 2.841e-07 301 2.052e-05 185 positive regulation of cellular protein metabolic process amigo.geneontol...
GO GO:0051172 View Gene Set 3.22e-07 580 2.313e-05 186 negative regulation of nitrogen compound metabolic process amigo.geneontol...
GO GO:0016301 View Gene Set 3.279e-07 769 2.343e-05 187 kinase activity amigo.geneontol...
GO GO:0043161 View Gene Set 3.557e-07 162 2.528e-05 188 proteasomal ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0035257 View Gene Set 3.709e-07 79 2.622e-05 189 nuclear hormone receptor binding amigo.geneontol...
GO GO:0070727 View Gene Set 4.214e-07 503 2.963e-05 190 cellular macromolecule localization amigo.geneontol...
GO GO:0051716 View Gene Set 4.771e-07 1102 3.337e-05 191 cellular response to stimulus amigo.geneontol...
GO GO:0044085 View Gene Set 4.86e-07 1167 3.382e-05 192 cellular component biogenesis amigo.geneontol...
GO GO:0000228 View Gene Set 5.316e-07 177 3.68e-05 193 nuclear chromosome amigo.geneontol...
GO GO:0034613 View Gene Set 5.511e-07 501 3.795e-05 194 cellular protein localization amigo.geneontol...
GO GO:0051247 View Gene Set 5.622e-07 317 3.852e-05 195 positive regulation of protein metabolic process amigo.geneontol...
GO GO:0019899 View Gene Set 6.339e-07 641 4.321e-05 196 enzyme binding amigo.geneontol...
GO GO:0000377 View Gene Set 7.375e-07 97 4.976e-05 197 RNA splicing via transesterification reactions with bulged adenosine as nucleophile amigo.geneontol...
GO GO:0000398 View Gene Set 7.375e-07 97 4.976e-05 197 nuclear mRNA splicing via spliceosome amigo.geneontol...
GO GO:0006886 View Gene Set 7.513e-07 439 5.044e-05 199 intracellular protein transport amigo.geneontol...
GO GO:0043933 View Gene Set 8.38e-07 836 5.598e-05 200 macromolecular complex subunit organization amigo.geneontol...

Gene Set Collection: Broad.c2.CGP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_DN View Gene Set 2.08e-106 825 4.976e-103 1 Genes down-regulated in fibroblasts expressing mutant forms of ERCC3 [Gene ID=2071] after UV irradiation. www.broad.mit.e...
Broad BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP View Gene Set 2.141e-78 783 2.56e-75 2 Genes up-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress. www.broad.mit.e...
Broad DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP View Gene Set 1.163e-69 1353 9.275e-67 3 Genes up-regulated in CD34+ [Gene ID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients compared to those from normal donors. www.broad.mit.e...
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN View Gene Set 1.273e-56 418 7.61e-54 4 Common down-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [Gene ID=2071] after UVC irradiation. www.broad.mit.e...
Broad KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP View Gene Set 1.21e-52 1180 5.787e-50 5 Genes up-regulated in TC71 and EWS502 cells (Ewing's sarcoma) upon knockdown of the EWSR1-FLII fusion [Gene ID=2130 2314]. www.broad.mit.e...
Broad DODD_NASOPHARYNGEAL_CARCINOMA_DN View Gene Set 1.436e-49 1253 5.723e-47 6 Genes down-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. www.broad.mit.e...
Broad DAZARD_RESPONSE_TO_UV_NHEK_DN View Gene Set 1.478e-44 256 5.052e-42 7 Genes down-regulated in NHEK cells (normal keratinocytes) by UV-B irradiation. www.broad.mit.e...
Broad BENPORATH_CYCLING_GENES View Gene Set 1.126e-42 630 3.367e-40 8 Genes showing cell-cycle stage-specific expression [PMID=12058064]. www.broad.mit.e...
Broad PUJANA_CHEK2_PCC_NETWORK View Gene Set 1.587e-40 744 4.218e-38 9 Genes constituting the CHEK2-PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient PCC >= 0.4) with that of CHEK2 [Gene ID=11200]. www.broad.mit.e...
Broad SHEN_SMARCA2_TARGETS_UP View Gene Set 8.726e-40 406 1.933e-37 10 Genes whose expression positively correlated with that of SMARCA2 [Gene ID=6595] in prostate cancer samples. www.broad.mit.e...
Broad GENTILE_UV_HIGH_DOSE_DN View Gene Set 8.888e-40 240 1.933e-37 10 Selected genes down-regulated in WS1 (fibroblast) in response to irradiation with high dose UV-C. www.broad.mit.e...
Broad PUJANA_BRCA1_PCC_NETWORK View Gene Set 5.849e-39 1582 1.166e-36 12 Genes constituting the BRCA1-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA1 [Gene ID=672] across a compendium of normal tissues. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_24HR_UP View Gene Set 2.213e-38 537 4.071e-36 13 Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h. www.broad.mit.e...
Broad BLALOCK_ALZHEIMERS_DISEASE_UP View Gene Set 9.615e-38 1641 1.643e-35 14 Genes up-regulated in brain from patients with Alzheimer's disease. www.broad.mit.e...
Broad ENK_UV_RESPONSE_KERATINOCYTE_DN View Gene Set 1.148e-37 475 1.83e-35 15 Genes down-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation. www.broad.mit.e...
Broad KIM_WT1_TARGETS_DN View Gene Set 6.369e-33 431 9.521e-31 16 Genes down-regulated in UB27 cells (osteosarcoma) at any time point after inducing the expression of a mutant form of WT1 [Gene ID=7490]. www.broad.mit.e...
Broad CAIRO_HEPATOBLASTOMA_CLASSES_UP View Gene Set 3.453e-30 577 4.858e-28 17 Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). www.broad.mit.e...
Broad NUYTTEN_EZH2_TARGETS_UP View Gene Set 2.75e-29 944 3.654e-27 18 Genes up-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [Gene ID=2146] by RNAi. www.broad.mit.e...
Broad KOBAYASHI_EGFR_SIGNALING_24HR_DN View Gene Set 3.486e-29 243 4.389e-27 19 Genes down-regulated in H1975 cells (non-small cell lung cancer NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 24h. www.broad.mit.e...
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN View Gene Set 6.029e-29 571 7.211e-27 20 Genes down-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. www.broad.mit.e...
Broad SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 View Gene Set 6.355e-29 435 7.239e-27 21 Cluster 6 of method A: up-regulation of these genes in patients with non???small cell lung cancer (NSCLC) predicts poor survival outcome. www.broad.mit.e...
Broad SCHLOSSER_SERUM_RESPONSE_DN View Gene Set 6.093e-28 666 6.625e-26 22 Cluster 4: genes down-regulated in B493-6 cells (B lymphocytes) upon serum stimulation but not affected by MYC [Gene ID=4609]. www.broad.mit.e...
Broad PUJANA_BRCA2_PCC_NETWORK View Gene Set 9.351e-28 410 9.725e-26 23 Genes constituting the BRCA2-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA2 [Gene ID=675] across a compendium of normal tissues. www.broad.mit.e...
Broad ONKEN_UVEAL_MELANOMA_UP View Gene Set 1.295e-27 739 1.29e-25 24 Genes up-regulated in uveal melanoma: class 2 vs class 1 tumors. www.broad.mit.e...
Broad WEI_MYCN_TARGETS_WITH_E_BOX View Gene Set 1.487e-26 757 1.423e-24 25 Genes whose promoters contain E-box motifs and whose expression changed in MYCN-3 cells (neuroblastoma) upon induction of MYCN [Gene ID=4613]. www.broad.mit.e...
Broad UDAYAKUMAR_MED1_TARGETS_DN View Gene Set 2.696e-26 230 2.481e-24 26 Genes down-regulated in HeLa cells after knockdown of MED1 [Gene ID=5469] by RNAi. www.broad.mit.e...
Broad MANALO_HYPOXIA_DN View Gene Set 5.551e-26 276 4.918e-24 27 Genes down-regulated in response to both hypoxia and overexpression of an active form of HIF1A [Gene ID=3091]. www.broad.mit.e...
Broad MITSIADES_RESPONSE_TO_APLIDIN_UP View Gene Set 1.646e-25 413 1.406e-23 28 Genes up-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164] a marine-derived compound with potential anti-cancer properties. www.broad.mit.e...
Broad NUYTTEN_EZH2_TARGETS_DN View Gene Set 2.033e-25 859 1.677e-23 29 Genes down-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [Gene ID=2146] by RNAi. www.broad.mit.e...
Broad ACEVEDO_LIVER_CANCER_UP View Gene Set 2.16e-24 915 1.722e-22 30 Genes up-regulated in hepatocellular carcinoma (HCC) compared to normal liver samples. www.broad.mit.e...
Broad WEST_ADRENOCORTICAL_TUMOR_UP View Gene Set 3.698e-24 283 2.853e-22 31 Up-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP View Gene Set 4.411e-24 681 3.297e-22 32 Genes up-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue. www.broad.mit.e...
Broad GEORGES_TARGETS_OF_MIR192_AND_MIR215 View Gene Set 1.651e-23 809 1.197e-21 33 Genes down-regulated in HCT116 cells (colon cancer) by expression of MIR192 or MIR215 [Gene ID=406967 406997] at 24 h. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP View Gene Set 1.781e-23 589 1.251e-21 34 Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. www.broad.mit.e...
Broad FOURNIER_ACINAR_DEVELOPMENT_LATE_2 View Gene Set 1.831e-23 265 1.251e-21 34 Genes identified by method 2 as coordinately down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro. www.broad.mit.e...
Broad BERENJENO_TRANSFORMED_BY_RHOA_UP View Gene Set 4.682e-23 485 3.111e-21 36 Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [Gene ID=387] off plasmid vector. www.broad.mit.e...
Broad DAZARD_UV_RESPONSE_CLUSTER_G6 View Gene Set 6.781e-23 122 4.384e-21 37 Cluster G6: genes increasingly down-regulated in NHEK cells (normal keratinocyte) after UV-B irradiation. www.broad.mit.e...
Broad MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN View Gene Set 9.388e-23 212 5.909e-21 38 Genes down-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199]. www.broad.mit.e...
Broad NUYTTEN_NIPP1_TARGETS_DN View Gene Set 1.047e-22 758 6.42e-21 39 Genes down-regulated in PC3 cells (prostate cancer) after knockdown of NIPP1 [Gene ID=5511] by RNAi. www.broad.mit.e...
Broad GARY_CD5_TARGETS_DN View Gene Set 1.082e-22 415 6.471e-21 40 Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. www.broad.mit.e...
Broad CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN View Gene Set 2.758e-22 639 1.609e-20 41 Genes down-regulated in APL (acute promyeolocytic leukemia) blasts expressing PML-RARA fusion [Gene ID=5371 5914] compared to normal promyeloblasts. www.broad.mit.e...
Broad CHEN_HOXA5_TARGETS_9HR_UP View Gene Set 1.382e-21 210 7.872e-20 42 Differentially expressed genes 9 hr after tinduction of HoxA5 [Gene ID=3205] expression in a breast cancer cell line. www.broad.mit.e...
Broad BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN View Gene Set 1.575e-21 599 8.761e-20 43 Genes down-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress. www.broad.mit.e...
Broad MITSIADES_RESPONSE_TO_APLIDIN_DN View Gene Set 2.691e-21 241 1.463e-19 44 Genes down-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164] a marine-derived compound with potential anti-cancer properties. www.broad.mit.e...
Broad STEIN_ESRRA_TARGETS View Gene Set 7.349e-21 508 3.906e-19 45 Genes regulated by ESRRA [Gene ID=2101] in MCF-7 cells (breast cancer). www.broad.mit.e...
Broad KIM_WT1_TARGETS_UP View Gene Set 8.179e-21 207 4.253e-19 46 Genes up-regulated in UB27 cells (osteosarcoma) at any time point after inducing the expression of a mutant form of WT1 [Gene ID=7490]. www.broad.mit.e...
Broad PUJANA_XPRSS_INT_NETWORK View Gene Set 2.666e-20 164 1.357e-18 47 Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200] in a compendium of normal tissues. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP View Gene Set 5.282e-20 869 2.632e-18 48 Genes up-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. www.broad.mit.e...
Broad ENK_UV_RESPONSE_EPIDERMIS_DN View Gene Set 1.026e-19 504 4.934e-18 49 Genes down-regulated in epidermis after to UVB irradiation. www.broad.mit.e...
Broad MILI_PSEUDOPODIA_HAPTOTAXIS_UP View Gene Set 1.031e-19 452 4.934e-18 49 Transcripts enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin FN1 [Gene ID=2335]. www.broad.mit.e...
Broad BLUM_RESPONSE_TO_SALIRASIB_DN View Gene Set 1.156e-19 332 5.423e-18 51 Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [Gene ID=3265]. www.broad.mit.e...
Broad LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN View Gene Set 1.668e-19 742 7.672e-18 52 Genes with copy number losses in primary neuroblastoma tumors. www.broad.mit.e...
Broad ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP View Gene Set 3.635e-19 806 1.641e-17 53 Genes up-regulated in liver tumor compared to the normal adjacent tissue. www.broad.mit.e...
Broad DAZARD_RESPONSE_TO_UV_SCC_DN View Gene Set 5.487e-19 96 2.43e-17 54 Genes down-regulated in SCC12B2 cells (squamous cell carcinoma) by UV-B irradiation. www.broad.mit.e...
Broad WONG_EMBRYONIC_STEM_CELL_CORE View Gene Set 7.312e-19 331 3.18e-17 55 The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module. www.broad.mit.e...
Broad ONKEN_UVEAL_MELANOMA_DN View Gene Set 1.149e-18 509 4.82e-17 56 Genes down-regulated in uveal melanoma: class 2 vs class 1 tumors. www.broad.mit.e...
Broad ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER View Gene Set 1.14e-18 138 4.82e-17 56 The 'Cervical Cancer Proliferation Cluster' (CCPC): genes whose expression in cervical carcinoma positively correlates with that of the HPV E6 and E7 oncogenes; they are also differentially expressed according to disease outcome. www.broad.mit.e...
Broad NAGASHIMA_NRG1_SIGNALING_UP View Gene Set 2.3e-18 171 9.485e-17 58 Genes up-regulated in MCF7 cells (breast cancer) after stimulation with NRG1 [Gene ID=3084]. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP View Gene Set 3.137e-18 716 1.272e-16 59 Genes up-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h. www.broad.mit.e...
Broad HELLER_HDAC_TARGETS_UP View Gene Set 4.425e-18 268 1.764e-16 60 Genes up-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN View Gene Set 5.681e-18 732 2.228e-16 61 Genes down-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN View Gene Set 6.898e-18 920 2.661e-16 62 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_6HR_DN View Gene Set 1.104e-17 160 4.191e-16 63 Genes down-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 6h. www.broad.mit.e...
Broad FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP View Gene Set 1.153e-17 532 4.309e-16 64 Genes diffierentially expressed in kidney biopsies from patients with well functioning kidneys more than 1-year post transplant compared to the biopsies from normal living kidney donors. www.broad.mit.e...
Broad BENPORATH_NANOG_TARGETS View Gene Set 6.541e-17 946 2.407e-15 65 Set 'Nanog targets': genes upregulated and identified by ChIP on chip as Nanog [Gene ID=79923] transcription factor targets in human embryonic stem cells. www.broad.mit.e...
Broad PUJANA_ATM_PCC_NETWORK View Gene Set 9.616e-17 1375 3.485e-15 66 Genes constituting the ATM-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of ATM [Gene ID=472] across a compendium of normal tissues. www.broad.mit.e...
Broad BLALOCK_ALZHEIMERS_DISEASE_DN View Gene Set 1.196e-16 1209 4.271e-15 67 Genes down-regulated in brain from patients with Alzheimer's disease. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN View Gene Set 1.412e-16 832 4.965e-15 68 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. www.broad.mit.e...
Broad KIM_WT1_TARGETS_8HR_UP View Gene Set 2.406e-16 160 8.342e-15 69 Genes up-regulated in UB27 cells (osteosarcoma) at 8 hr after inducing the expression of a mutant form of WT1 [Gene ID=7490]. www.broad.mit.e...
Broad RUIZ_TNC_TARGETS_DN View Gene Set 3.337e-16 138 1.14e-14 70 Genes down-regulated in T98G cells (glioblastoma) by TNC [Gene ID=3371]. www.broad.mit.e...
Broad ZHANG_BREAST_CANCER_PROGENITORS_UP View Gene Set 3.432e-16 370 1.156e-14 71 Genes changed in cancer stem cells isolated from mammary tumors compared to the non-tumorigenic cells. www.broad.mit.e...
Broad SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP View Gene Set 4.233e-16 143 1.406e-14 72 Up-regulated genes whose expression correlated with histologic grade of invasive breast cancer tumors: comparison of grade 1 vs grade 3. www.broad.mit.e...
Broad BENPORATH_MYC_MAX_TARGETS View Gene Set 4.442e-16 768 1.456e-14 73 Set 'Myc targets2': targets of c-Myc [Gene ID=4609] and Max [Gene ID=4149] identified by ChIP on chip in a Burkitt???s lymphoma cell line; overlap set. www.broad.mit.e...
Broad DANG_BOUND_BY_MYC View Gene Set 5.383e-16 1045 1.74e-14 74 Genes whose promoters are bound by MYC [Gene ID=4609] according to MYC Target Gene Database. www.broad.mit.e...
Broad PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN View Gene Set 6.455e-16 140 2.059e-14 75 Genes down-regulated in OV-90 cells (ovarian cancer) exposed to ascites which inhibited invasion. www.broad.mit.e...
Broad BASAKI_YBX1_TARGETS_UP View Gene Set 7.344e-16 279 2.312e-14 76 Genes up-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [Gene ID=4904] knockdown by RNAi. www.broad.mit.e...
Broad DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP View Gene Set 1.529e-15 242 4.751e-14 77 Genes up-regulated in HEK293 cells (embryonic kidney) at 6 h 12 h or 24 h after infection with reovirus strain T3A (known as a strong inducer of apoptosis). www.broad.mit.e...
Broad HORIUCHI_WTAP_TARGETS_DN View Gene Set 1.578e-15 289 4.84e-14 78 Genes down-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [Gene ID=9589] by RNAi. www.broad.mit.e...
Broad CAIRO_HEPATOBLASTOMA_UP View Gene Set 1.658e-15 200 5.021e-14 79 Genes up-regulated in hepatoblastoma samples compared to normal liver tissue. www.broad.mit.e...
Broad BIDUS_METASTASIS_UP View Gene Set 1.713e-15 203 5.121e-14 80 Genes up-regulated in endometroid endometrial tumors from patients with lymph node metastases compared to those without the metastases. www.broad.mit.e...
Broad GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP View Gene Set 2.617e-15 180 7.73e-14 81 Genes up-regulated in quiescent CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors compared to the dividing cells from CML (chronic myeloid leukemia) patients. www.broad.mit.e...
Broad CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN View Gene Set 3.06e-15 444 8.925e-14 82 Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. www.broad.mit.e...
Broad LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN View Gene Set 1.613e-14 158 4.648e-13 83 Genes down-regulated in Wilm's tumor samples compared to fetal kidney. www.broad.mit.e...
Broad HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP View Gene Set 1.666e-14 399 4.744e-13 84 Genes up-regulated in multiple myeloma (MM) cell lines treated with both decitabine [PubChem=451668] TSA [PubChem=5562]. www.broad.mit.e...
Broad MUELLER_PLURINET View Gene Set 2.358e-14 294 6.636e-13 85 Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells embryonical carcinomas and induced pluripotent cells). www.broad.mit.e...
Broad LINDGREN_BLADDER_CANCER_CLUSTER_3_UP View Gene Set 3.253e-14 314 9.049e-13 86 Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors. www.broad.mit.e...
Broad MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP View Gene Set 6.808e-14 359 1.872e-12 87 The postradiation tumor escape signature: genes up-regulated in tumors from irradiated stroma vs those from non-irradiated stroma. www.broad.mit.e...
Broad SENESE_HDAC3_TARGETS_UP View Gene Set 7.246e-14 471 1.969e-12 88 Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC3 [Gene ID=8841] by RNAi. www.broad.mit.e...
Broad BENPORATH_SOX2_TARGETS View Gene Set 1.387e-13 704 3.728e-12 89 Set 'Sox2 targets': genes upregulated and identified by ChIP on chip as SOX2 [Gene ID=6657] transcription factor targets in human embryonic stem cells. www.broad.mit.e...
Broad CROONQUIST_NRAS_SIGNALING_DN View Gene Set 1.905e-13 62 5.063e-12 90 Genes down-regulated in ANBL-6 cell line (multiple myeloma MM) expressing a constantly active form of NRAS [Gene ID=4893] off a plasmid vector compared to those grown in the presence of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_2HR_DN View Gene Set 2.206e-13 85 5.799e-12 91 Genes down-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 2h. www.broad.mit.e...
Broad CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 View Gene Set 2.436e-13 446 6.335e-12 92 The 'group 5 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 but not ERBB2 [Gene ID=2099 2064]. www.broad.mit.e...
Broad BLUM_RESPONSE_TO_SALIRASIB_UP View Gene Set 6.1e-13 240 1.569e-11 93 Selected genes up-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [Gene ID=3265]. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP View Gene Set 6.236e-13 184 1.587e-11 94 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G3 defined by unsupervised clustering. www.broad.mit.e...
Broad MASSARWEH_TAMOXIFEN_RESISTANCE_UP View Gene Set 6.727e-13 531 1.694e-11 95 Genes up-regulated in breast cancer tumors (formed by MCF-7 xenografts) resistant to tamoxifen [PubChem=5376]. www.broad.mit.e...
Broad PUJANA_BRCA_CENTERED_NETWORK View Gene Set 6.857e-13 92 1.709e-11 96 Genes constituting the BRCA-centered network (BCN). www.broad.mit.e...
Broad RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN View Gene Set 9.09e-13 351 2.242e-11 97 Genes down-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids. www.broad.mit.e...
Broad STEIN_ESRRA_TARGETS_UP View Gene Set 1.468e-12 368 3.584e-11 98 Genes up-regulated by ESRRA [Gene ID=2101] only. www.broad.mit.e...
Broad BILD_HRAS_ONCOGENIC_SIGNATURE View Gene Set 1.831e-12 248 4.424e-11 99 Genes selected in supervised analyses to discriminate cells expressing activated HRAS [Gene ID=3265] oncogene from control cells expressing GFP. www.broad.mit.e...
Broad BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP View Gene Set 1.919e-12 382 4.59e-11 100 Genes up-regulated in patients at the incipient stage of Alzheimer's disease. www.broad.mit.e...
Broad CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP View Gene Set 2.123e-12 135 5.027e-11 101 Top 200 marker genes up-regulated in the 'proliferation' subclass of hepatocellular carcinoma (HCC); characterized by increased proliferation high levels of serum AFP [Gene ID=174] and chromosomal instability. www.broad.mit.e...
Broad SMITH_TERT_TARGETS_UP View Gene Set 2.203e-12 128 5.166e-11 102 Genes consistently up-regulated in HMEC cells (primary mammary epithelium) upon expression of TERT [Gene ID=7015] off a retroviral vector. www.broad.mit.e...
Broad MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN View Gene Set 2.437e-12 121 5.659e-11 103 Genes distinguishing in multiple myeloma (MM) samples with lower expression of TACI [Gene ID=23495]. www.broad.mit.e...
Broad RAMALHO_STEMNESS_UP View Gene Set 2.478e-12 192 5.699e-11 104 Genes enriched in embryonic neural and hematopoietic stem cells. www.broad.mit.e...
Broad KIM_WT1_TARGETS_12HR_UP View Gene Set 3.441e-12 157 7.839e-11 105 Genes up-regulated in UB27 cells (osteosarcoma) at 12 hr after inducing the expression of a mutated form of WT1 [Gene ID=7490]. www.broad.mit.e...
Broad PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP View Gene Set 6.864e-12 53 1.549e-10 106 The XPRSS-Int network genes up-regulated in breast tumors from patients with germline mutations in BRCA1 [Gene ID=672] compared to those with the wild type allele. www.broad.mit.e...
Broad TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C View Gene Set 8.424e-12 436 1.883e-10 107 Genes down-regulated in HCT116 cells (colon cancer) upon expression of MIR34B or MIR34C [Gene ID=407041 407042] microRNAs. www.broad.mit.e...
Broad FARMER_BREAST_CANCER_APOCRINE_VS_BASAL View Gene Set 9.836e-12 321 2.178e-10 108 Genes which best discriminate between two groups of breast cancer according the status of ESR1 and AR [Gene ID=2099 367]: apocrine (ESR1- AR+) vs basal (ESR1- AR-). www.broad.mit.e...
Broad CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 View Gene Set 1.25e-11 681 2.743e-10 109 The 'group 3 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [Gene ID=2099 2064]. www.broad.mit.e...
Broad MARKEY_RB1_ACUTE_LOF_DN View Gene Set 1.423e-11 201 3.094e-10 110 Genes down-regulated in adult fibroblasts with inactivated RB1 [Gene ID=5925] by Cre-lox: acute loss of function (LOF) of RB1. www.broad.mit.e...
Broad WANG_LMO4_TARGETS_DN View Gene Set 2.099e-11 327 4.522e-10 111 Genes down-regulated in MCF7 cells (breast cancer) engineered to conditionally express LMO4 [Gene ID=8543] by a Tet Off system. www.broad.mit.e...
Broad LINDGREN_BLADDER_CANCER_CLUSTER_1_DN View Gene Set 2.224e-11 368 4.75e-10 112 Genes whose expression profile is specific to Custer I of urothelial cell carcinoma (UCC) tumors. www.broad.mit.e...
Broad KIM_WT1_TARGETS_12HR_DN View Gene Set 2.27e-11 200 4.805e-10 113 Genes down-regulated in UB27 cells (osteosarcoma) at 12 hr after inducing the expression of a mutated form of WT1 [Gene ID=7490]. www.broad.mit.e...
Broad WINNEPENNINCKX_MELANOMA_METASTASIS_UP View Gene Set 2.335e-11 152 4.899e-10 114 Genes from the 254-gene classifier which were up-regulated in melanoma patients with a reported distant metastasis within 4 years. www.broad.mit.e...
Broad TARTE_PLASMA_CELL_VS_PLASMABLAST_DN View Gene Set 2.904e-11 303 6.039e-10 115 Genes down-regulated in mature plasma cells compared with plasmablastic B lymphocytes. www.broad.mit.e...
Broad RICKMAN_METASTASIS_UP View Gene Set 4.091e-11 316 8.436e-10 116 Genes up-regulated in metastatic vs non-metastatic HNSCC (head and neck squamous cell carcinoma) samples. www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_14HR_UP View Gene Set 5.63e-11 150 1.151e-09 117 Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not up-regulated at the previous time point 12 h. www.broad.mit.e...
Broad MILI_PSEUDOPODIA_HAPTOTAXIS_DN View Gene Set 6.602e-11 607 1.327e-09 118 Transcripts depleted from pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin FN1 [Gene ID=2335]. www.broad.mit.e...
Broad SESTO_RESPONSE_TO_UV_C2 View Gene Set 6.603e-11 53 1.327e-09 118 Cluster 2: genes changed in primary keratinocytes by UVB irradiation. www.broad.mit.e...
Broad PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN View Gene Set 6.742e-11 123 1.333e-09 120 Down-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes. www.broad.mit.e...
Broad CROONQUIST_IL6_DEPRIVATION_DN View Gene Set 6.711e-11 80 1.333e-09 120 Genes down-regulated in the ANBL-6 cell line (multiple myeloma MM) after withdrawal of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad PODAR_RESPONSE_TO_ADAPHOSTIN_UP View Gene Set 6.892e-11 140 1.351e-09 122 Up-regulated genes in MM1.S cells (multiple myeloma) treated with adaphostin [PubChem=387042] a tyrosine kinase inhibitor with anticancer properties. www.broad.mit.e...
Broad VECCHI_GASTRIC_CANCER_EARLY_UP View Gene Set 9.937e-11 408 1.933e-09 123 Up-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. www.broad.mit.e...
Broad JIANG_HYPOXIA_NORMAL View Gene Set 1.326e-10 213 2.558e-09 124 Genes up-regulated in RPTEC cells (normal kidney) by hypoxia. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_24HR_DN View Gene Set 1.398e-10 208 2.675e-09 125 Genes down-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h. www.broad.mit.e...
Broad CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN View Gene Set 1.472e-10 437 2.794e-09 126 Genes down-regulated in luminal-like breast cancer cell lines compared to the basal-like ones. www.broad.mit.e...
Broad GEORGES_CELL_CYCLE_MIR192_TARGETS View Gene Set 1.492e-10 59 2.81e-09 127 Experimentally validated direct targets of MIR192 [Gene ID=406967] microRNA; MIR192 caused cell cycle arrest in HCT116 cells (colon cancer). www.broad.mit.e...
Broad GENTILE_RESPONSE_CLUSTER_D3 View Gene Set 1.507e-10 44 2.816e-09 128 Cluster d3: genes progressively down-regulated in WS1 cells (fibroblast) through 12 h irradiation with high dose UV-C. www.broad.mit.e...
Broad OSMAN_BLADDER_CANCER_UP View Gene Set 1.697e-10 387 3.147e-09 129 Genes up-regulated in blood samples from bladder cancer patients. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM View Gene Set 2.124e-10 154 3.908e-09 130 Cluster 7: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] and down-regulated by the combination of MYC and serum. www.broad.mit.e...
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN View Gene Set 2.839e-10 75 5.184e-09 131 Genes exclusively down-regulated in fibroblasts expressing the XP/CS mutant form of ERCC3 [Gene ID=2071] after high dose UVC irradiation. www.broad.mit.e...
Broad REN_ALVEOLAR_RHABDOMYOSARCOMA_DN View Gene Set 2.948e-10 402 5.343e-09 132 Genes commonly down-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [Gene ID=5077 2308] fusion. www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_18HR_UP View Gene Set 3.093e-10 175 5.563e-09 133 Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 18 h time point that were not up-regulated at the previous time point 16 h. www.broad.mit.e...
Broad BORCZUK_MALIGNANT_MESOTHELIOMA_UP View Gene Set 4.503e-10 290 8.038e-09 134 Genes up-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma. www.broad.mit.e...
Broad STEIN_ESRRA_TARGETS_DN View Gene Set 4.946e-10 100 8.763e-09 135 Genes down-regulated by ESRRA [Gene ID=2101] only. www.broad.mit.e...
Broad NUYTTEN_NIPP1_TARGETS_UP View Gene Set 5.933e-10 657 1.044e-08 136 Genes up-regulated in PC3 cells (prostate cancer) after knockdown of NIPP1 [Gene ID=5511] by RNAi. www.broad.mit.e...
Broad AMIT_EGF_RESPONSE_240_HELA View Gene Set 6.652e-10 59 1.161e-08 137 Genes whose expression peaked at 240 min after stimulation of HeLa cells with EGF [Gene ID=1950]. www.broad.mit.e...
Broad DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN View Gene Set 8.518e-10 224 1.476e-08 138 Genes down-regulated in HEK293 cells (embryonic kidney) at 6 h 12 h or 24 h after infection with reovirus strain T3A (known as a strong inducer of apoptosis). www.broad.mit.e...
Broad PROVENZANI_METASTASIS_UP View Gene Set 1.017e-09 188 1.748e-08 139 Genes up-regulated in polysomal and total RNA samples from SW480 cells (primary colorectal carcinoma CRC) compared to the SW620 cells (lymph node metastasis from the same individual). www.broad.mit.e...
Broad KANG_DOXORUBICIN_RESISTANCE_UP View Gene Set 1.023e-09 53 1.748e-08 139 Genes differentialy expressed in gastric cancer cell lines: doxorubicin [PubChem=31703] resistant vs sensitive. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP View Gene Set 1.06e-09 220 1.798e-08 141 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors. www.broad.mit.e...
Broad MISSIAGLIA_REGULATED_BY_METHYLATION_DN View Gene Set 1.119e-09 96 1.885e-08 142 Genes down-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668] a DNA hypomethylating agent similar to azacitidine [PubChem=9444]. www.broad.mit.e...
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN View Gene Set 1.164e-09 76 1.948e-08 143 Genes exclusively down-regulated in fibroblasts expressing the TTD mutant form of ERCC3 [Gene ID=2071] after UVC irradiation. www.broad.mit.e...
Broad NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN View Gene Set 1.177e-09 583 1.948e-08 144 Down-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone. www.broad.mit.e...
Broad SENESE_HDAC1_TARGETS_UP View Gene Set 1.181e-09 427 1.948e-08 144 Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [Gene ID=3065] by RNAi. www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_6HR_DN View Gene Set 1.28e-09 159 2.097e-08 146 Genes down-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 6 h time point that were not down-regulated at the previous time point 4 h. www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_16HR_UP View Gene Set 1.305e-09 216 2.124e-08 147 Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 16 h time point that were not up-regulated at the previous time point 14 h. www.broad.mit.e...
Broad MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN View Gene Set 1.346e-09 317 2.175e-08 148 The postradiation tumor escape signature: genes down-regulated in tumors from irradiated stroma vs those from non-irradiated stroma. www.broad.mit.e...
Broad GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN View Gene Set 1.388e-09 450 2.229e-08 149 Genes down-regulated in erythroid progenitor cells isolated from bone marrow of patients with Diamond-Blackfan anemia (DBA) and mutated RPS19 [Gene ID=6223]. www.broad.mit.e...
Broad WANG_CLIM2_TARGETS_DN View Gene Set 1.593e-09 166 2.54e-08 150 Genes down-regulated in MCF7 cells (breast cancer) engineered to conditionally express a dominant negative form of CLIM2 [Gene ID=8861] by a Tet Off system. www.broad.mit.e...
Broad LIU_VMYB_TARGETS_UP View Gene Set 2.167e-09 121 3.432e-08 151 Genes up-regulated in MCF-7 cells (breast cancer) by overexpression of v-MYB oncogenic varian of CMYB [Gene ID=4602] off adenovirus vector. www.broad.mit.e...
Broad HAMAI_APOPTOSIS_VIA_TRAIL_UP View Gene Set 2.242e-09 328 3.529e-08 152 Genes up-regulated in T1 cells (primary melanoma sensitive to TRAIL [Gene ID=8743]) compared to G1 cells (metastatic melanoma resistant to TRAIL). www.broad.mit.e...
Broad BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING View Gene Set 2.275e-09 489 3.556e-08 153 Genes whose expression in suboptimally debulked ovarian tumors is associated with survival prognosis. www.broad.mit.e...
Broad HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP View Gene Set 2.316e-09 93 3.597e-08 154 Genes up-regulated during differentiation from large pre-BII to small pre-BII lymphocyte. www.broad.mit.e...
Broad UEDA_PERIFERAL_CLOCK View Gene Set 2.452e-09 146 3.785e-08 155 Molecular timetable composed of 162 time-indicating genes (182 probes) in the peripheral (liver) clock. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN View Gene Set 2.54e-09 485 3.894e-08 156 Genes down-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue. www.broad.mit.e...
Broad HAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN View Gene Set 3.078e-09 111 4.69e-08 157 Genes down-regulated in T helper cells (defines as CD4+) isolated from patients with mucosis fungoides compared to those from normal control donors. www.broad.mit.e...
Broad SESTO_RESPONSE_TO_UV_C5 View Gene Set 3.285e-09 46 4.973e-08 158 Cluster 5: genes changed in primary keratinocytes by UVB irradiation. www.broad.mit.e...
Broad PARENT_MTOR_SIGNALING_UP View Gene Set 3.585e-09 541 5.393e-08 159 Genes up-regulated in HepaRG cells (liver cancer) expressing constituvely active form of MTOR [Gene ID=2475]. www.broad.mit.e...
Broad LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER View Gene Set 3.703e-09 167 5.535e-08 160 Overexpressed genes with amplified copy number across 27 non-small cell lung cancer (NSCLC) cell lines. www.broad.mit.e...
Broad NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP View Gene Set 4.255e-09 263 6.321e-08 161 Up-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone. www.broad.mit.e...
Broad WANG_LMO4_TARGETS_UP View Gene Set 4.83e-09 341 7.091e-08 162 Genes up-regulated in MCF7 cells (breast cancer) engineered to conditionally express LMO4 [Gene ID=8543] by a Tet Off system. www.broad.mit.e...
Broad GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN View Gene Set 4.862e-09 86 7.091e-08 162 Genes down-regulated in quiescent vs dividing CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors. www.broad.mit.e...
Broad BILD_MYC_ONCOGENIC_SIGNATURE View Gene Set 4.861e-09 187 7.091e-08 162 Genes selected in supervised analyses to discriminate cells expressing c-Myc [Gene ID=4609] from control cells expressing GFP. www.broad.mit.e...
Broad GALE_APL_WITH_FLT3_MUTATED_UP View Gene Set 4.902e-09 52 7.107e-08 165 Genes up-regulated in acute promyelocytic leukemia (APL) patients with mutated FLT3 [Gene ID=2322]. www.broad.mit.e...
Broad FUJII_YBX1_TARGETS_DN View Gene Set 5.289e-09 139 7.622e-08 166 Genes down-regulated in MCF-7 cells (breast cancer) after knockdown of YBX1 [Gene ID=4904] by RNAi. www.broad.mit.e...
Broad BENPORATH_ES_1 View Gene Set 5.358e-09 367 7.675e-08 167 Set 'ES exp1': genes overexpressed in human embryonic stem cells according to 5 or more out of 20 profiling studies. www.broad.mit.e...
Broad FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP View Gene Set 8.808e-09 539 1.254e-07 168 Genes up-regulated in monocyte-derived dendritic cells (MDDC) after stimulation with galecin-1 (lectin LGALS1) [Gene ID=3956] compared to that with bacterial lipopolysaccharide (LPS). www.broad.mit.e...
Broad DOANE_RESPONSE_TO_ANDROGEN_DN View Gene Set 9.943e-09 235 1.407e-07 169 Genes down-regulated in MDA-MB-453 cells (class A ER(-) [Gene ID=2099] breast cancer) after exposure to the androgen R1881 [PubChem=13766]. www.broad.mit.e...
Broad LEE_EARLY_T_LYMPHOCYTE_UP View Gene Set 1.028e-08 80 1.446e-07 170 Genes up-regulated at early stages of progenitor T lymphocyte maturation compared to the late stages. www.broad.mit.e...
Broad MILI_PSEUDOPODIA_CHEMOTAXIS_DN View Gene Set 1.291e-08 430 1.805e-07 171 Transcripts depleted in pseudopodia of NIH/3T3 cells (fibroblast) in response to the chemotactic migration stimulus by lysophosphatidic acid (LPA) [PubChem=3988]. www.broad.mit.e...
Broad LIU_SOX4_TARGETS_DN View Gene Set 1.311e-08 297 1.824e-07 172 Genes down-regulated in LNCaP cells (prostate cancer) by overexpression of SOX4 [Gene ID=6659] and up-regulated by its RNAi knockdown. www.broad.mit.e...
Broad THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN View Gene Set 1.32e-08 215 1.825e-07 173 Genes down-regulated in polymorphonuclear neutrophilic granulocytes (PMNs) attracted to skin wounds. www.broad.mit.e...
Broad FARMER_BREAST_CANCER_BASAL_VS_LULMINAL View Gene Set 1.332e-08 317 1.831e-07 174 Genes which best discriminated between two groups of breast cancer according to the status of ESR1 and AR [Gene ID=2099 367]: basal (ESR1- AR-) and luminal (ESR1+ AR+). www.broad.mit.e...
Broad BASAKI_YBX1_TARGETS_DN View Gene Set 1.35e-08 356 1.845e-07 175 Genes down-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [Gene ID=4904] knockdown by RNAi. www.broad.mit.e...
Broad CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP View Gene Set 1.407e-08 228 1.912e-07 176 Genes up-regulated in SH-SY5Y cells (neuroblastoma) after treatment with epoxomicin [PubChem=3035402] a protease inhibitor causing apoptosis. www.broad.mit.e...
Broad WILCOX_PRESPONSE_TO_ROGESTERONE_UP View Gene Set 1.504e-08 143 2.032e-07 177 Genes up-regulated in primary cultures of ovarian surface epithlium cells exposed to progesterone [PubChem=5994] for 5 days. www.broad.mit.e...
Broad DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP View Gene Set 1.619e-08 317 2.175e-07 178 Genes up-regulated in mARMS (molecular ARMS) compared to the mERMS (molecular ERMS) class of rhabdomyosarcoma tumors. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN View Gene Set 1.654e-08 160 2.211e-07 179 Genes down-regulated in metastatic breast cancer tumors having type 2 amplification in the 20q13 region; involves MYBL2 STK6 and ZNF217 [Gene ID=4605 6790 7764] www.broad.mit.e...
Broad AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN View Gene Set 1.664e-08 218 2.211e-07 180 Down-regulated genes whose expression correlates with copy number losses in pancreatic adenocarcinoma cell lines and primary tumor specimens. www.broad.mit.e...
Broad ELVIDGE_HYPOXIA_DN View Gene Set 1.677e-08 136 2.216e-07 181 Genes down-regulated in MCF7 cells (breast cancer) under hypoxia conditions. www.broad.mit.e...
Broad PRAMOONJAGO_SOX4_TARGETS_UP View Gene Set 2.129e-08 49 2.798e-07 182 Genes up-regulated in ACC3 cells (adenoid cystic carcinoma) after knockdown of SOX4 [Gene ID=6659] by RNAi. www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_24HR_UP View Gene Set 2.301e-08 146 3.008e-07 183 Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 24 h time point that were not up-regulated at the previous time point 20 h. www.broad.mit.e...
Broad GENTILE_UV_RESPONSE_CLUSTER_D4 View Gene Set 2.42e-08 49 3.146e-07 184 Cluster d4: genes progressively down-regulated in WS1 cells (fibroblast) through 12 h after irradiation with high dose UV-C. www.broad.mit.e...
Broad PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP View Gene Set 2.656e-08 175 3.434e-07 185 Up-regulated genes in head and neck cancer compared to cervical carcinoma samples. www.broad.mit.e...
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_UP View Gene Set 3.321e-08 301 4.259e-07 186 Genes up-regulated in fibroblasts expressing mutant forms of ERCC3 [Gene ID=2071] after UV irradiation. www.broad.mit.e...
Broad SESTO_RESPONSE_TO_UV_C0 View Gene Set 3.329e-08 106 4.259e-07 186 Cluster 0: genes changed in primary keratinocytes by UVB irradiation. www.broad.mit.e...
Broad GARY_CD5_TARGETS_UP View Gene Set 3.469e-08 463 4.411e-07 188 Genes up-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. www.broad.mit.e...
Broad WELCSH_BRCA1_TARGETS_1_DN View Gene Set 3.504e-08 124 4.411e-07 188 Upregulated by induction of exogenous BRCA1 in EcR-293 cells www.broad.mit.e...
Broad RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP View Gene Set 3.5e-08 331 4.411e-07 188 Genes up-regulated in peripheral blood monocytes by CSF2RB (GM-CSF) [Gene ID=1437] and IL4 [Gene ID=3565]. www.broad.mit.e...
Broad RODRIGUES_DCC_TARGETS_DN View Gene Set 3.605e-08 121 4.515e-07 191 Genes down-regulated in HCT8/S1 cells (colon cancer) which normally lack DCC [Gene ID=9423] compared to those stably expressing wild type DCC off a plasmid vector. www.broad.mit.e...
Broad PAL_PRMT5_TARGETS_UP View Gene Set 4.046e-08 178 5.041e-07 192 Genes up-regulated in NIH-3T3 cells (fibroblast) after knockdown of PRMT5 [Gene ID=10419] by RNAi. www.broad.mit.e...
Broad TAKAO_RESPONSE_TO_UVB_RADIATION_DN View Gene Set 4.508e-08 89 5.587e-07 193 Genes down-regulated in primary tissue culture of epidermal kerationcytes after UVB irradiation. www.broad.mit.e...
Broad KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN View Gene Set 5.063e-08 306 6.212e-07 194 Genes down-regulated in TC71 and EWS502 cells (Ewing's sarcoma) upon knockdown of the EWSR1-FLII fusion [Gene ID=2130 2314]. www.broad.mit.e...
Broad AMIT_SERUM_RESPONSE_120_MCF10A View Gene Set 5.064e-08 64 6.212e-07 194 Genes whose expression peaked at 120 min after stimulation of MCF10A cells with serum. www.broad.mit.e...
Broad WANG_SMARCE1_TARGETS_DN View Gene Set 5.607e-08 329 6.843e-07 196 Genes down-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [Gene ID=6605] off a retroviral vector. www.broad.mit.e...
Broad AMUNDSON_RESPONSE_TO_ARSENITE View Gene Set 5.852e-08 180 7.106e-07 197 Genes discriminating responses to sodium arsenite [PubChem ID=26435] from other stresses. www.broad.mit.e...
Broad ODONNELL_TFRC_TARGETS_DN View Gene Set 6.269e-08 131 7.574e-07 198 Genes dpwn-regulated in P493-6 cells (B lymphocyte) upon knockdown of TFRC [Gene ID=7037] by RNAi. www.broad.mit.e...
Broad HAN_SATB1_TARGETS_UP View Gene Set 6.774e-08 303 8.142e-07 199 Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of SATB1 [Gene ID=6304] by RNAi. www.broad.mit.e...
Broad LANDIS_ERBB2_BREAST_TUMORS_324_UP View Gene Set 7.261e-08 132 8.685e-07 200 The 324 genes identified by two analytical methods as changed in the mammary tumors induced by transgenic expression of ERBB2 [Gene ID=2064]. www.broad.mit.e...

Gene Set Collection: Broad.c2.CP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad ST_P38_MAPK_PATHWAY View Gene Set 0.0002286 35 0.01074 1 p38 MAPK Pathway www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.BIOCARTA

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad BIOCARTA_VDR_PATHWAY View Gene Set 0.0001025 12 0.01331 1 Control of Gene Expression by Vitamin D Receptor www.broad.mit.e...
Broad BIOCARTA_CELLCYCLE_PATHWAY View Gene Set 0.0002453 23 0.01331 1 Cyclins and Cell Cycle Regulation www.broad.mit.e...
Broad BIOCARTA_DEATH_PATHWAY View Gene Set 0.0002404 33 0.01331 1 Induction of apoptosis through DR3 and DR4/5 Death Receptors www.broad.mit.e...
Broad BIOCARTA_MITOCHONDRIA_PATHWAY View Gene Set 0.0001912 21 0.01331 1 Role of Mitochondria in Apoptotic Signaling www.broad.mit.e...
Broad BIOCARTA_MAPK_PATHWAY View Gene Set 0.0009266 87 0.02976 5 MAPKinase Signaling Pathway www.broad.mit.e...
Broad BIOCARTA_NTHI_PATHWAY View Gene Set 0.0009601 24 0.02976 5 NFkB activation by Nontypeable Hemophilus influenzae www.broad.mit.e...
Broad BIOCARTA_RARRXR_PATHWAY View Gene Set 0.000796 15 0.02976 5 Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells www.broad.mit.e...
Broad BIOCARTA_MCM_PATHWAY View Gene Set 0.00183 18 0.04964 8 CDK Regulation of DNA Replication www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.KEGG

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad KEGG_CELL_CYCLE View Gene Set 1.095e-12 128 2.038e-10 1 Cell cycle www.broad.mit.e...
Broad KEGG_SPLICEOSOME View Gene Set 3.132e-10 118 2.913e-08 2 Spliceosome www.broad.mit.e...
Broad KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS View Gene Set 2.099e-08 138 1.302e-06 3 Ubiquitin mediated proteolysis www.broad.mit.e...
Broad KEGG_OOCYTE_MEIOSIS View Gene Set 8.323e-05 114 0.003303 4 Oocyte meiosis www.broad.mit.e...
Broad KEGG_P53_SIGNALING_PATHWAY View Gene Set 8.878e-05 69 0.003303 4 p53 signaling pathway www.broad.mit.e...
Broad KEGG_RNA_DEGRADATION View Gene Set 0.0001527 59 0.004733 6 RNA degradation www.broad.mit.e...
Broad KEGG_DNA_REPLICATION View Gene Set 0.0006186 36 0.01474 7 DNA replication www.broad.mit.e...
Broad KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION View Gene Set 0.0006342 86 0.01474 7 Progesterone-mediated oocyte maturation www.broad.mit.e...
Broad KEGG_CIRCADIAN_RHYTHM_MAMMAL View Gene Set 0.0008177 13 0.0169 9 Circadian rhythm - mammal www.broad.mit.e...
Broad KEGG_STEROID_BIOSYNTHESIS View Gene Set 0.0009899 17 0.01841 10 Steroid biosynthesis www.broad.mit.e...
Broad KEGG_PYRIMIDINE_METABOLISM View Gene Set 0.00188 98 0.03179 11 Pyrimidine metabolism www.broad.mit.e...
Broad KEGG_BASE_EXCISION_REPAIR View Gene Set 0.002567 35 0.03979 12 Base excision repair www.broad.mit.e...
Broad KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT View Gene Set 0.002886 38 0.04129 13 SNARE interactions in vesicular transport www.broad.mit.e...
Broad KEGG_INOSITOL_PHOSPHATE_METABOLISM View Gene Set 0.003281 54 0.04359 14 Inositol phosphate metabolism www.broad.mit.e...
Broad KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS View Gene Set 0.004124 15 0.04441 15 Terpenoid backbone biosynthesis www.broad.mit.e...
Broad KEGG_LYSOSOME View Gene Set 0.004094 122 0.04441 15 Lysosome www.broad.mit.e...
Broad KEGG_WNT_SIGNALING_PATHWAY View Gene Set 0.003935 151 0.04441 15 Wnt signaling pathway www.broad.mit.e...
Broad KEGG_CHRONIC_MYELOID_LEUKEMIA View Gene Set 0.004297 73 0.04441 15 Chronic myeloid leukemia www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.REACTOME

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad REACTOME_CELL_CYCLE_MITOTIC View Gene Set 2.324e-18 306 9.994e-16 1 Genes involved in Cell Cycle Mitotic www.broad.mit.e...
Broad REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA View Gene Set 7.444e-12 128 1.6e-09 2 Genes involved in Processing of Capped Intron-Containing Pre-mRNA www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_RNA View Gene Set 7.008e-10 95 1.004e-07 3 Genes involved in Metabolism of RNA www.broad.mit.e...
Broad REACTOME_MITOTIC_M_M_G1_PHASES View Gene Set 1.266e-09 157 1.361e-07 4 Genes involved in Mitotic M-M/G1 phases www.broad.mit.e...
Broad REACTOME_MITOTIC_PROMETAPHASE View Gene Set 8.445e-09 92 7.263e-07 5 Genes involved in Mitotic Prometaphase www.broad.mit.e...
Broad REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS View Gene Set 1.546e-07 124 8.308e-06 6 Genes involved in Elongation and Processing of Capped Transcripts www.broad.mit.e...
Broad REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT View Gene Set 1.501e-07 142 8.308e-06 6 Genes involved in Formation and Maturation of mRNA Transcript www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING View Gene Set 1.176e-07 97 8.308e-06 6 Genes involved in mRNA Splicing www.broad.mit.e...
Broad REACTOME_CELL_CYCLE_CHECKPOINTS View Gene Set 3.106e-07 110 1.484e-05 9 Genes involved in Cell Cycle Checkpoints www.broad.mit.e...
Broad REACTOME_G1_S_TRANSITION View Gene Set 1.019e-06 102 4.209e-05 10 Genes involved in G1/S Transition www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRON_CONTAINING_TRANSCRIPT View Gene Set 1.077e-06 42 4.209e-05 10 Genes involved in Transport of Mature mRNA derived from an Intron-Containing Transcript www.broad.mit.e...
Broad REACTOME_S_PHASE View Gene Set 1.962e-06 103 7.031e-05 12 Genes involved in S Phase www.broad.mit.e...
Broad REACTOME_CHOLESTEROL_BIOSYNTHESIS View Gene Set 2.342e-06 21 7.748e-05 13 Genes involved in Cholesterol biosynthesis www.broad.mit.e...
Broad REACTOME_G2_M_TRANSITION View Gene Set 2.562e-06 84 7.87e-05 14 Genes involved in G2/M Transition www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_MRNA View Gene Set 6.147e-06 45 0.0001762 15 Genes involved in Metabolism of mRNA www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_THE_SLBP_INDEPENDENT_MATURE_MRNA View Gene Set 8.896e-06 32 0.0002391 16 Genes involved in Transport of the SLBP independent Mature mRNA www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS View Gene Set 1.084e-05 29 0.0002741 17 Genes involved in Transport of Ribonucleoproteins into the Host Nucleus www.broad.mit.e...
Broad REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY View Gene Set 1.176e-05 29 0.000281 18 Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery www.broad.mit.e...
Broad REACTOME_SNRNP_ASSEMBLY View Gene Set 1.375e-05 50 0.0003112 19 Genes involved in snRNP Assembly www.broad.mit.e...
Broad REACTOME_G2_M_CHECKPOINTS View Gene Set 1.563e-05 43 0.0003361 20 Genes involved in G2/M Checkpoints www.broad.mit.e...
Broad REACTOME_GENE_EXPRESSION View Gene Set 1.666e-05 415 0.0003412 21 Genes involved in Gene Expression www.broad.mit.e...
Broad REACTOME_REV_MEDIATED_NUCLEAR_EXPORT_OF_HIV1_RNA View Gene Set 2.338e-05 31 0.000457 22 Genes involved in Rev-mediated nuclear export of HIV-1 RNA www.broad.mit.e...
Broad REACTOME_DEADENYLATION_OF_MRNA View Gene Set 2.794e-05 21 0.0005224 23 Genes involved in Deadenylation of mRNA www.broad.mit.e...
Broad REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN View Gene Set 3.387e-05 30 0.0005862 24 Genes involved in Nuclear import of Rev protein www.broad.mit.e...
Broad REACTOME_REGULATION_OF_APC_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE View Gene Set 3.408e-05 71 0.0005862 24 Genes involved in Regulation of APC/C activators between G1/S and early anaphase www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS View Gene Set 4.107e-05 37 0.0006793 26 Genes involved in Activation of ATR in response to replication stress www.broad.mit.e...
Broad REACTOME_VPR_MEDIATED_NUCLEAR_IMPORT_OF_PICS View Gene Set 4.415e-05 31 0.0007031 27 Genes involved in Vpr-mediated nuclear import of PICs www.broad.mit.e...
Broad REACTOME_CYCLIN_A1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION View Gene Set 7.17e-05 15 0.001063 28 Genes involved in Cyclin A1 associated events during G2/M transition www.broad.mit.e...
Broad REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE View Gene Set 7.027e-05 90 0.001063 28 Genes involved in Late Phase of HIV Life Cycle www.broad.mit.e...
Broad REACTOME_HIV_LIFE_CYCLE View Gene Set 7.826e-05 103 0.001122 30 Genes involved in HIV Life Cycle www.broad.mit.e...
Broad REACTOME_SYNTHESIS_OF_DNA View Gene Set 0.0001112 89 0.001543 31 Genes involved in Synthesis of DNA www.broad.mit.e...
Broad REACTOME_HIV_INFECTION View Gene Set 0.0001866 183 0.002507 32 Genes involved in HIV Infection www.broad.mit.e...
Broad REACTOME_INACTIVATION_OF_APC_VIA_DIRECT_INHIBITION_OF_THE_APCOMPLEX View Gene Set 0.0002014 18 0.002624 33 Genes involved in Inactivation of APC/C via direct inhibition of the APC/C complex www.broad.mit.e...
Broad REACTOME_PHOSPHORYLATION_OF_THE_APC View Gene Set 0.0002224 17 0.002813 34 Genes involved in Phosphorylation of the APC/C www.broad.mit.e...
Broad REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN View Gene Set 0.0002308 29 0.002835 35 Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein www.broad.mit.e...
Broad REACTOME_CENTROSOME_MATURATION View Gene Set 0.0002547 72 0.003042 36 Genes involved in Centrosome maturation www.broad.mit.e...
Broad REACTOME_MAP_KINASES_ACTIVATION_IN_TLR_CASCADE View Gene Set 0.0002958 44 0.003438 37 Genes involved in MAP kinases activation in TLR cascade www.broad.mit.e...
Broad REACTOME_TRAF6_MEDIATED_INDUCTION_OF_THE_ANTIVIRAL_CYTOKINE_IFN_ALPHA_BETA_CASCADE View Gene Set 0.0003315 53 0.003752 38 Genes involved in TRAF6 Mediated Induction of the antiviral cytokine IFN-alphaeta cascade www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX View Gene Set 0.000402 30 0.004432 39 Genes involved in Activation of the pre-replicative complex www.broad.mit.e...
Broad REACTOME_DNA_STRAND_ELONGATION View Gene Set 0.0004371 31 0.004698 40 Genes involved in DNA strand elongation www.broad.mit.e...
Broad REACTOME_CONVERSION_FROM_APC_CDC20_TO_APC_CDH1_IN_LATE_ANAPHASE View Gene Set 0.0004815 17 0.00505 41 Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase www.broad.mit.e...
Broad REACTOME_APCDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B View Gene Set 0.0005016 18 0.005135 42 Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B www.broad.mit.e...
Broad REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES View Gene Set 0.0005881 30 0.005881 43 Genes involved in MAPK targets/Nuclear events mediated by MAP kinases www.broad.mit.e...
Broad REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ View Gene Set 0.0007934 58 0.007754 44 Genes involved in Cyclin E associated events during G1/S transition www.broad.mit.e...
Broad REACTOME_TOLL_LIKE_RECEPTOR_3_CASCADE View Gene Set 0.0009046 59 0.008644 45 Genes involved in Toll Like Receptor 3 (TLR3) Cascade www.broad.mit.e...
Broad REACTOME_UNWINDING_OF_DNA View Gene Set 0.001034 11 0.009663 46 Genes involved in Unwinding of DNA www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION View Gene Set 0.001117 83 0.01022 47 Genes involved in RNA Polymerase II Transcription www.broad.mit.e...
Broad REACTOME_DNA_REPLICATION_PRE_INITIATION View Gene Set 0.001206 76 0.0108 48 Genes involved in DNA Replication Pre-Initiation www.broad.mit.e...
Broad REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION View Gene Set 0.001336 24 0.01173 49 Genes involved in Nuclear Events (kinase and transcription factor activation) www.broad.mit.e...
Broad REACTOME_MRNA_3_END_PROCESSING View Gene Set 0.001378 25 0.01185 50 Genes involved in mRNA 3-end processing www.broad.mit.e...
Broad REACTOME_CDC20_PHOSPHO_APC_MEDIATED_DEGRADATION_OF_CYCLIN_A View Gene Set 0.001429 63 0.01205 51 Genes involved in Cdc20:Phospho-APC/C mediated degradation of Cyclin A www.broad.mit.e...
Broad REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES View Gene Set 0.001552 62 0.0128 52 Genes involved in Loss of Nlp from mitotic centrosomes www.broad.mit.e...
Broad REACTOME_ORC1_REMOVAL_FROM_CHROMATIN View Gene Set 0.001578 63 0.0128 52 Genes involved in Orc1 removal from chromatin www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION View Gene Set 0.001735 34 0.01381 54 Genes involved in RNA Polymerase III Transcription www.broad.mit.e...
Broad REACTOME_DNA_REPAIR View Gene Set 0.002174 102 0.01699 55 Genes involved in DNA Repair www.broad.mit.e...
Broad REACTOME_APOPTOSIS View Gene Set 0.002289 129 0.01757 56 Genes involved in Apoptosis www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION View Gene Set 0.002433 29 0.01835 57 Genes involved in RNA Polymerase III Transcription Initiation www.broad.mit.e...
Broad REACTOME_TRANSFORMATION_OF_LANOSTEROL_TO_CHOLESTEROL View Gene Set 0.002577 10 0.0191 58 Genes involved in Transformation of lanosterol to cholesterol www.broad.mit.e...
Broad REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION View Gene Set 0.002805 33 0.02045 59 Genes involved in E2F mediated regulation of DNA replication www.broad.mit.e...
Broad REACTOME_SIGNALLING_BY_NGF View Gene Set 0.002878 216 0.02062 60 Genes involved in Signalling by NGF www.broad.mit.e...
Broad REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS View Gene Set 0.00327 120 0.02305 61 Genes involved in Host Interactions of HIV factors www.broad.mit.e...
Broad REACTOME_GENERIC_TRANSCRIPTION_PATHWAY View Gene Set 0.003737 35 0.02592 62 Genes involved in Generic Transcription Pathway www.broad.mit.e...
Broad REACTOME_GLUCOSE_TRANSPORT View Gene Set 0.004076 38 0.02782 63 Genes involved in Glucose transport www.broad.mit.e...
Broad REACTOME_SPHINGOLIPID_METABOLISM View Gene Set 0.004144 32 0.02784 64 Genes involved in Sphingolipid metabolism www.broad.mit.e...
Broad REACTOME_ERK_MAPK_TARGETS View Gene Set 0.005316 21 0.03454 65 Genes involved in ERK/MAPK targets www.broad.mit.e...
Broad REACTOME_G1_PHASE View Gene Set 0.005372 16 0.03454 65 Genes involved in G1 Phase www.broad.mit.e...
Broad REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE View Gene Set 0.005382 13 0.03454 65 Genes involved in mRNA Decay by 5' to 3' Exoribonuclease www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING_MINOR_PATHWAY View Gene Set 0.005557 38 0.03514 68 Genes involved in mRNA Splicing - Minor Pathway www.broad.mit.e...
Broad REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC View Gene Set 0.006647 57 0.04097 69 Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C www.broad.mit.e...
Broad REACTOME_RHO_GTPASE_CYCLE View Gene Set 0.00667 124 0.04097 69 Genes involved in Rho GTPase cycle www.broad.mit.e...
Broad REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS View Gene Set 0.006843 29 0.04144 71 Genes involved in Intrinsic Pathway for Apoptosis www.broad.mit.e...
Broad REACTOME_P75NTR_SIGNALS_VIA_NFKB View Gene Set 0.007856 13 0.04662 72 Genes involved in p75NTR signals via NF-kB www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER View Gene Set 0.007915 22 0.04662 72 Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter www.broad.mit.e...
Broad REACTOME_VITAMIN_B5_(PANTOTHENATE)_METABOLISM View Gene Set 0.008345 11 0.04849 74 Genes involved in Vitamin B5 (pantothenate) metabolism www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER View Gene Set 0.008663 20 0.04922 75 Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter www.broad.mit.e...
Broad REACTOME_SIGNALING_BY_WNT View Gene Set 0.0087 58 0.04922 75 Genes involved in Signaling by Wnt www.broad.mit.e...

Gene Set Collection: Broad.c3.MIR

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad TGAATGT MIR-181A MIR-181B MIR-181C MIR-181D View Gene Set 4.756e-15 418 1.051e-12 1 Targets of MicroRNA TGAATGT MIR-181A MIR-181B MIR-181C MIR-181D www.broad.mit.e... MIR-181A... MIR-181B... MIR-181C... MIR-181D...
Broad ACCAAAG MIR-9 View Gene Set 1.948e-14 428 2.152e-12 2 Targets of MicroRNA ACCAAAG MIR-9 www.broad.mit.e... MIR-9...
Broad TGCCTTA MIR-124A View Gene Set 2.76e-13 471 2.033e-11 3 Targets of MicroRNA TGCCTTA MIR-124A www.broad.mit.e... MIR-124A...
Broad GCACTTT MIR-17-5P MIR-20A MIR-106A MIR-106B MIR-20B MIR-519D View Gene Set 7.742e-13 506 2.9e-11 4 Targets of MicroRNA GCACTTT MIR-17-5P MIR-20A MIR-106A MIR-106B MIR-20B MIR-519D www.broad.mit.e... MIR-17-5P... MIR-20A... MIR-106A... MIR-106B... MIR-20B... MIR-519D...
Broad AATGTGA MIR-23A MIR-23B View Gene Set 7.873e-13 356 2.9e-11 4 Targets of MicroRNA AATGTGA MIR-23A MIR-23B www.broad.mit.e... MIR-23A... MIR-23B...
Broad TTGCCAA MIR-182 View Gene Set 6.141e-13 274 2.9e-11 4 Targets of MicroRNA TTGCCAA MIR-182 www.broad.mit.e... MIR-182...
Broad CAGTATT MIR-200B MIR-200C MIR-429 View Gene Set 4.433e-12 386 1.347e-10 7 Targets of MicroRNA CAGTATT MIR-200B MIR-200C MIR-429 www.broad.mit.e... MIR-200B... MIR-200C... MIR-429...
Broad TTTGCAC MIR-19A MIR-19B View Gene Set 4.877e-12 440 1.347e-10 7 Targets of MicroRNA TTTGCAC MIR-19A MIR-19B www.broad.mit.e... MIR-19A... MIR-19B...
Broad TTTGCAG MIR-518A-2 View Gene Set 1.494e-11 174 3.667e-10 9 Targets of MicroRNA TTTGCAG MIR-518A-2 www.broad.mit.e... MIR-518A-2...
Broad TGCTGCT MIR-15A MIR-16 MIR-15B MIR-195 MIR-424 MIR-497 View Gene Set 1.98e-11 512 4.377e-10 10 Targets of MicroRNA TGCTGCT MIR-15A MIR-16 MIR-15B MIR-195 MIR-424 MIR-497 www.broad.mit.e... MIR-15A... MIR-16... MIR-15B... MIR-195... MIR-424... MIR-497...
Broad CAGTGTT MIR-141 MIR-200A View Gene Set 3.444e-11 262 6.918e-10 11 Targets of MicroRNA CAGTGTT MIR-141 MIR-200A www.broad.mit.e... MIR-141... MIR-200A...
Broad TGTTTAC MIR-30A-5P MIR-30C MIR-30D MIR-30B MIR-30E-5P View Gene Set 3.903e-11 492 7.189e-10 12 Targets of MicroRNA TGTTTAC MIR-30A-5P MIR-30C MIR-30D MIR-30B MIR-30E-5P www.broad.mit.e... MIR-30A-5P... MIR-30C... MIR-30D... MIR-30B... MIR-30E-5P...
Broad GTGCCTT MIR-506 View Gene Set 5.553e-11 605 9.439e-10 13 Targets of MicroRNA GTGCCTT MIR-506 www.broad.mit.e... MIR-506...
Broad TGCACTT MIR-519C MIR-519B MIR-519A View Gene Set 5.107e-10 377 8.061e-09 14 Targets of MicroRNA TGCACTT MIR-519C MIR-519B MIR-519A www.broad.mit.e... MIR-519C... MIR-519B... MIR-519A...
Broad TACTTGA MIR-26A MIR-26B View Gene Set 9.761e-10 258 1.438e-08 15 Targets of MicroRNA TACTTGA MIR-26A MIR-26B www.broad.mit.e... MIR-26A... MIR-26B...
Broad TGTGTGA MIR-377 View Gene Set 1.977e-09 162 2.731e-08 16 Targets of MicroRNA TGTGTGA MIR-377 www.broad.mit.e... MIR-377...
Broad CAGCTTT MIR-320 View Gene Set 2.425e-09 220 3.153e-08 17 Targets of MicroRNA CAGCTTT MIR-320 www.broad.mit.e... MIR-320...
Broad TTTGTAG MIR-520D View Gene Set 9.479e-09 279 1.164e-07 18 Targets of MicroRNA TTTGTAG MIR-520D www.broad.mit.e... MIR-520D...
Broad GTACTGT MIR-101 View Gene Set 1.072e-08 221 1.247e-07 19 Targets of MicroRNA GTACTGT MIR-101 www.broad.mit.e... MIR-101...
Broad CTTTGTA MIR-524 View Gene Set 2.122e-08 375 2.344e-07 20 Targets of MicroRNA CTTTGTA MIR-524 www.broad.mit.e... MIR-524...
Broad ACCATTT MIR-522 View Gene Set 2.692e-08 137 2.833e-07 21 Targets of MicroRNA ACCATTT MIR-522 www.broad.mit.e... MIR-522...
Broad TGCACTG MIR-148A MIR-152 MIR-148B View Gene Set 4.44e-08 252 4.46e-07 22 Targets of MicroRNA TGCACTG MIR-148A MIR-152 MIR-148B www.broad.mit.e... MIR-148A... MIR-152... MIR-148B...
Broad ACTGTGA MIR-27A MIR-27B View Gene Set 5.557e-08 385 5.34e-07 23 Targets of MicroRNA ACTGTGA MIR-27A MIR-27B www.broad.mit.e... MIR-27A... MIR-27B...
Broad TAATGTG MIR-323 View Gene Set 6.429e-08 135 5.92e-07 24 Targets of MicroRNA TAATGTG MIR-323 www.broad.mit.e... MIR-323...
Broad GCAAAAA MIR-129 View Gene Set 7.509e-08 152 6.638e-07 25 Targets of MicroRNA GCAAAAA MIR-129 www.broad.mit.e... MIR-129...
Broad CATTTCA MIR-203 View Gene Set 1.013e-07 235 8.611e-07 26 Targets of MicroRNA CATTTCA MIR-203 www.broad.mit.e... MIR-203...
Broad ATGTACA MIR-493 View Gene Set 1.103e-07 261 9.025e-07 27 Targets of MicroRNA ATGTACA MIR-493 www.broad.mit.e... MIR-493...
Broad AAAGGGA MIR-204 MIR-211 View Gene Set 1.675e-07 191 1.322e-06 28 Targets of MicroRNA AAAGGGA MIR-204 MIR-211 www.broad.mit.e... MIR-204... MIR-211...
Broad ATATGCA MIR-448 View Gene Set 2.787e-07 184 2.124e-06 29 Targets of MicroRNA ATATGCA MIR-448 www.broad.mit.e... MIR-448...
Broad ATACTGT MIR-144 View Gene Set 2.894e-07 173 2.132e-06 30 Targets of MicroRNA ATACTGT MIR-144 www.broad.mit.e... MIR-144...
Broad GTGCAAT MIR-25 MIR-32 MIR-92 MIR-363 MIR-367 View Gene Set 3.556e-07 260 2.535e-06 31 Targets of MicroRNA GTGCAAT MIR-25 MIR-32 MIR-92 MIR-363 MIR-367 www.broad.mit.e... MIR-25... MIR-32... MIR-92... MIR-363... MIR-367...
Broad AACTGAC MIR-223 View Gene Set 4.108e-07 84 2.837e-06 32 Targets of MicroRNA AACTGAC MIR-223 www.broad.mit.e... MIR-223...
Broad TTGGAGA MIR-515-5P MIR-519E View Gene Set 4.251e-07 120 2.847e-06 33 Targets of MicroRNA TTGGAGA MIR-515-5P MIR-519E www.broad.mit.e... MIR-515-5P... MIR-519E...
Broad CTATGCA MIR-153 View Gene Set 4.451e-07 182 2.893e-06 34 Targets of MicroRNA CTATGCA MIR-153 www.broad.mit.e... MIR-153...
Broad TTGCACT MIR-130A MIR-301 MIR-130B View Gene Set 5.121e-07 335 3.234e-06 35 Targets of MicroRNA TTGCACT MIR-130A MIR-301 MIR-130B www.broad.mit.e... MIR-130A... MIR-301... MIR-130B...
Broad GTGACTT MIR-224 View Gene Set 6.39e-07 135 3.923e-06 36 Targets of MicroRNA GTGACTT MIR-224 www.broad.mit.e... MIR-224...
Broad CACTGTG MIR-128A MIR-128B View Gene Set 8.036e-07 276 4.8e-06 37 Targets of MicroRNA CACTGTG MIR-128A MIR-128B www.broad.mit.e... MIR-128A... MIR-128B...
Broad CTTGTAT MIR-381 View Gene Set 9.316e-07 167 5.418e-06 38 Targets of MicroRNA CTTGTAT MIR-381 www.broad.mit.e... MIR-381...
Broad GAGCCAG MIR-149 View Gene Set 1.056e-06 125 5.984e-06 39 Targets of MicroRNA GAGCCAG MIR-149 www.broad.mit.e... MIR-149...
Broad TCCAGAT MIR-516-5P View Gene Set 1.391e-06 93 7.688e-06 40 Targets of MicroRNA TCCAGAT MIR-516-5P www.broad.mit.e... MIR-516-5P...
Broad AGCACTT MIR-93 MIR-302A MIR-302B MIR-302C MIR-302D MIR-372 MIR-373 MIR-520E MIR-520A MIR-526B MIR-520B MIR-520C MIR-520D View Gene Set 3.067e-06 281 1.653e-05 41 Targets of MicroRNA AGCACTT MIR-93 MIR-302A MIR-302B MIR-302C MIR-302D MIR-372 MIR-373 MIR-520E MIR-520A MIR-526B MIR-520B MIR-520C MIR-520D www.broad.mit.e... MIR-93... MIR-302A... MIR-302B... MIR-302C... MIR-302D... MIR-372... MIR-373... MIR-520E... MIR-520A... MIR-526B... MIR-520B... MIR-520C... MIR-520D...
Broad ACATTCC MIR-1 MIR-206 View Gene Set 3.163e-06 248 1.665e-05 42 Targets of MicroRNA ACATTCC MIR-1 MIR-206 www.broad.mit.e... MIR-1... MIR-206...
Broad AAGCACA MIR-218 View Gene Set 3.259e-06 336 1.675e-05 43 Targets of MicroRNA AAGCACA MIR-218 www.broad.mit.e... MIR-218...
Broad GACTGTT MIR-212 MIR-132 View Gene Set 3.686e-06 134 1.851e-05 44 Targets of MicroRNA GACTGTT MIR-212 MIR-132 www.broad.mit.e... MIR-212... MIR-132...
Broad GTATTAT MIR-369-3P View Gene Set 4.726e-06 174 2.321e-05 45 Targets of MicroRNA GTATTAT MIR-369-3P www.broad.mit.e... MIR-369-3P...
Broad GCATTTG MIR-105 View Gene Set 5.679e-06 143 2.728e-05 46 Targets of MicroRNA GCATTTG MIR-105 www.broad.mit.e... MIR-105...
Broad GCACCTT MIR-18A MIR-18B View Gene Set 7.055e-06 90 3.317e-05 47 Targets of MicroRNA GCACCTT MIR-18A MIR-18B www.broad.mit.e... MIR-18A... MIR-18B...
Broad ATTCTTT MIR-186 View Gene Set 7.822e-06 232 3.601e-05 48 Targets of MicroRNA ATTCTTT MIR-186 www.broad.mit.e... MIR-186...
Broad AACTGGA MIR-145 View Gene Set 1.025e-05 191 4.624e-05 49 Targets of MicroRNA AACTGGA MIR-145 www.broad.mit.e... MIR-145...
Broad CTTTGCA MIR-527 View Gene Set 1.227e-05 198 5.425e-05 50 Targets of MicroRNA CTTTGCA MIR-527 www.broad.mit.e... MIR-527...
Broad GAGCTGG MIR-337 View Gene Set 1.318e-05 133 5.713e-05 51 Targets of MicroRNA GAGCTGG MIR-337 www.broad.mit.e... MIR-337...
Broad CTCTGGA MIR-520A MIR-525 View Gene Set 1.391e-05 128 5.91e-05 52 Targets of MicroRNA CTCTGGA MIR-520A MIR-525 www.broad.mit.e... MIR-520A... MIR-525...
Broad CATGTAA MIR-496 View Gene Set 1.448e-05 150 6.036e-05 53 Targets of MicroRNA CATGTAA MIR-496 www.broad.mit.e... MIR-496...
Broad CTACCTC LET-7A LET-7B LET-7C LET-7D LET-7E LET-7F MIR-98 LET-7G LET-7I View Gene Set 1.631e-05 329 6.676e-05 54 Targets of MicroRNA CTACCTC LET-7A LET-7B LET-7C LET-7D LET-7E LET-7F MIR-98 LET-7G LET-7I www.broad.mit.e... LET-7A... LET-7B... LET-7C... LET-7D... LET-7E... LET-7F... MIR-98... LET-7G... LET-7I...
Broad TTTTGAG MIR-373 View Gene Set 1.951e-05 189 7.841e-05 55 Targets of MicroRNA TTTTGAG MIR-373 www.broad.mit.e... MIR-373...
Broad ATACCTC MIR-202 View Gene Set 2.058e-05 150 8.123e-05 56 Targets of MicroRNA ATACCTC MIR-202 www.broad.mit.e... MIR-202...
Broad GTGCAAA MIR-507 View Gene Set 2.254e-05 113 8.739e-05 57 Targets of MicroRNA GTGCAAA MIR-507 www.broad.mit.e... MIR-507...
Broad ACACTAC MIR-142-3P View Gene Set 2.352e-05 110 8.963e-05 58 Targets of MicroRNA ACACTAC MIR-142-3P www.broad.mit.e... MIR-142-3P...
Broad CTGAGCC MIR-24 View Gene Set 2.755e-05 195 0.0001032 59 Targets of MicroRNA CTGAGCC MIR-24 www.broad.mit.e... MIR-24...
Broad TGGTGCT MIR-29A MIR-29B MIR-29C View Gene Set 2.867e-05 436 0.0001056 60 Targets of MicroRNA TGGTGCT MIR-29A MIR-29B MIR-29C www.broad.mit.e... MIR-29A... MIR-29B... MIR-29C...
Broad GACAATC MIR-219 View Gene Set 3.169e-05 124 0.0001148 61 Targets of MicroRNA GACAATC MIR-219 www.broad.mit.e... MIR-219...
Broad CTCAGGG MIR-125B MIR-125A View Gene Set 3.233e-05 277 0.0001152 62 Targets of MicroRNA CTCAGGG MIR-125B MIR-125A www.broad.mit.e... MIR-125B... MIR-125A...
Broad ACTTTAT MIR-142-5P View Gene Set 3.365e-05 250 0.000118 63 Targets of MicroRNA ACTTTAT MIR-142-5P www.broad.mit.e... MIR-142-5P...
Broad AAGGGAT MIR-188 View Gene Set 3.87e-05 65 0.0001336 64 Targets of MicroRNA AAGGGAT MIR-188 www.broad.mit.e... MIR-188...
Broad ACTGTAG MIR-139 View Gene Set 4.431e-05 111 0.0001507 65 Targets of MicroRNA ACTGTAG MIR-139 www.broad.mit.e... MIR-139...
Broad TCATCTC MIR-143 View Gene Set 4.626e-05 126 0.0001549 66 Targets of MicroRNA TCATCTC MIR-143 www.broad.mit.e... MIR-143...
Broad GTGTTGA MIR-505 View Gene Set 5.618e-05 85 0.0001853 67 Targets of MicroRNA GTGTTGA MIR-505 www.broad.mit.e... MIR-505...
Broad GGCACTT MIR-519E View Gene Set 7.73e-05 108 0.0002512 68 Targets of MicroRNA GGCACTT MIR-519E www.broad.mit.e... MIR-519E...
Broad TATTATA MIR-374 View Gene Set 8.509e-05 237 0.0002725 69 Targets of MicroRNA TATTATA MIR-374 www.broad.mit.e... MIR-374...
Broad GTCTTCC MIR-7 View Gene Set 0.0001219 132 0.0003849 70 Targets of MicroRNA GTCTTCC MIR-7 www.broad.mit.e... MIR-7...
Broad TGCTTTG MIR-330 View Gene Set 0.0001647 278 0.0005128 71 Targets of MicroRNA TGCTTTG MIR-330 www.broad.mit.e... MIR-330...
Broad GAGACTG MIR-452 View Gene Set 0.0001774 78 0.000537 72 Targets of MicroRNA GAGACTG MIR-452 www.broad.mit.e... MIR-452...
Broad GGCAGTG MIR-324-3P View Gene Set 0.000177 82 0.000537 72 Targets of MicroRNA GGCAGTG MIR-324-3P www.broad.mit.e... MIR-324-3P...
Broad AAGCACT MIR-520F View Gene Set 0.0001975 198 0.0005898 74 Targets of MicroRNA AAGCACT MIR-520F www.broad.mit.e... MIR-520F...
Broad AGGAGTG MIR-483 View Gene Set 0.0002033 57 0.0005992 75 Targets of MicroRNA AGGAGTG MIR-483 www.broad.mit.e... MIR-483...
Broad GTAAACC MIR-299-5P View Gene Set 0.0002143 44 0.0006233 76 Targets of MicroRNA GTAAACC MIR-299-5P www.broad.mit.e... MIR-299-5P...
Broad CACCAGC MIR-138 View Gene Set 0.0002175 173 0.0006242 77 Targets of MicroRNA CACCAGC MIR-138 www.broad.mit.e... MIR-138...
Broad GCTTGAA MIR-498 View Gene Set 0.0002676 96 0.0007581 78 Targets of MicroRNA GCTTGAA MIR-498 www.broad.mit.e... MIR-498...
Broad ATGCTGC MIR-103 MIR-107 View Gene Set 0.0002811 185 0.0007865 79 Targets of MicroRNA ATGCTGC MIR-103 MIR-107 www.broad.mit.e... MIR-103... MIR-107...
Broad GGCAGCT MIR-22 View Gene Set 0.0003148 198 0.0008695 80 Targets of MicroRNA GGCAGCT MIR-22 www.broad.mit.e... MIR-22...
Broad GTGCCAA MIR-96 View Gene Set 0.0003224 265 0.0008796 81 Targets of MicroRNA GTGCCAA MIR-96 www.broad.mit.e... MIR-96...
Broad ATGTTAA MIR-302C View Gene Set 0.0003279 206 0.0008807 82 Targets of MicroRNA ATGTTAA MIR-302C www.broad.mit.e... MIR-302C...
Broad TACAATC MIR-508 View Gene Set 0.0003308 55 0.0008807 82 Targets of MicroRNA TACAATC MIR-508 www.broad.mit.e... MIR-508...
Broad AAAGACA MIR-511 View Gene Set 0.0003368 163 0.000886 84 Targets of MicroRNA AAAGACA MIR-511 www.broad.mit.e... MIR-511...
Broad AAAGGAT MIR-501 View Gene Set 0.0003635 107 0.0009452 85 Targets of MicroRNA AAAGGAT MIR-501 www.broad.mit.e... MIR-501...
Broad ATAGGAA MIR-202 View Gene Set 0.0003717 86 0.0009552 86 Targets of MicroRNA ATAGGAA MIR-202 www.broad.mit.e... MIR-202...
Broad ATAACCT MIR-154 View Gene Set 0.0004022 51 0.001022 87 Targets of MicroRNA ATAACCT MIR-154 www.broad.mit.e... MIR-154...
Broad GCTCTTG MIR-335 View Gene Set 0.0004335 70 0.001074 88 Targets of MicroRNA GCTCTTG MIR-335 www.broad.mit.e... MIR-335...
Broad GGCACAT MIR-455 View Gene Set 0.0004358 46 0.001074 88 Targets of MicroRNA GGCACAT MIR-455 www.broad.mit.e... MIR-455...
Broad CTGTTAC MIR-194 View Gene Set 0.0004375 90 0.001074 88 Targets of MicroRNA CTGTTAC MIR-194 www.broad.mit.e... MIR-194...
Broad GTGCCAT MIR-183 View Gene Set 0.0004695 152 0.00114 91 Targets of MicroRNA GTGCCAT MIR-183 www.broad.mit.e... MIR-183...
Broad TGTATGA MIR-485-3P View Gene Set 0.0005966 116 0.001433 92 Targets of MicroRNA TGTATGA MIR-485-3P www.broad.mit.e... MIR-485-3P...
Broad AGGCACT MIR-515-3P View Gene Set 0.0006228 74 0.00148 93 Targets of MicroRNA AGGCACT MIR-515-3P www.broad.mit.e... MIR-515-3P...
Broad TCTATGA MIR-376A MIR-376B View Gene Set 0.0006683 71 0.001571 94 Targets of MicroRNA TCTATGA MIR-376A MIR-376B www.broad.mit.e... MIR-376A... MIR-376B...
Broad CCACACA MIR-147 View Gene Set 0.0006903 56 0.001606 95 Targets of MicroRNA CCACACA MIR-147 www.broad.mit.e... MIR-147...
Broad AAGCAAT MIR-137 View Gene Set 0.000707 176 0.001623 96 Targets of MicroRNA AAGCAAT MIR-137 www.broad.mit.e... MIR-137...
Broad CAGCCTC MIR-485-5P View Gene Set 0.0007122 117 0.001623 96 Targets of MicroRNA CAGCCTC MIR-485-5P www.broad.mit.e... MIR-485-5P...
Broad AAGCCAT MIR-135A MIR-135B View Gene Set 0.0007733 283 0.001744 98 Targets of MicroRNA AAGCCAT MIR-135A MIR-135B www.broad.mit.e... MIR-135A... MIR-135B...
Broad CACTTTG MIR-520G MIR-520H View Gene Set 0.0008342 206 0.001862 99 Targets of MicroRNA CACTTTG MIR-520G MIR-520H www.broad.mit.e... MIR-520G... MIR-520H...
Broad AGCTCCT MIR-28 View Gene Set 0.0008616 78 0.001904 100 Targets of MicroRNA AGCTCCT MIR-28 www.broad.mit.e... MIR-28...
Broad CCTGTGA MIR-513 View Gene Set 0.0009001 105 0.001969 101 Targets of MicroRNA CCTGTGA MIR-513 www.broad.mit.e... MIR-513...
Broad AGGGCAG MIR-18A View Gene Set 0.0009273 116 0.002009 102 Targets of MicroRNA AGGGCAG MIR-18A www.broad.mit.e... MIR-18A...
Broad GGGCATT MIR-365 View Gene Set 0.001038 102 0.002227 103 Targets of MicroRNA GGGCATT MIR-365 www.broad.mit.e... MIR-365...
Broad ATAAGCT MIR-21 View Gene Set 0.001212 104 0.002576 104 Targets of MicroRNA ATAAGCT MIR-21 www.broad.mit.e... MIR-21...
Broad ACAGGGT MIR-10A MIR-10B View Gene Set 0.001236 106 0.002602 105 Targets of MicroRNA ACAGGGT MIR-10A MIR-10B www.broad.mit.e... MIR-10A... MIR-10B...
Broad CCTGCTG MIR-214 View Gene Set 0.001298 194 0.002705 106 Targets of MicroRNA CCTGCTG MIR-214 www.broad.mit.e... MIR-214...
Broad TCTGGAC MIR-198 View Gene Set 0.001547 69 0.003195 107 Targets of MicroRNA TCTGGAC MIR-198 www.broad.mit.e... MIR-198...
Broad ATGTAGC MIR-221 MIR-222 View Gene Set 0.001691 114 0.003357 108 Targets of MicroRNA ATGTAGC MIR-221 MIR-222 www.broad.mit.e... MIR-221... MIR-222...
Broad GGCCAGT MIR-193A MIR-193B View Gene Set 0.001702 81 0.003357 108 Targets of MicroRNA GGCCAGT MIR-193A MIR-193B www.broad.mit.e... MIR-193A... MIR-193B...
Broad CAAGGAT MIR-362 View Gene Set 0.001678 53 0.003357 108 Targets of MicroRNA CAAGGAT MIR-362 www.broad.mit.e... MIR-362...
Broad ATGCAGT MIR-217 View Gene Set 0.001671 93 0.003357 108 Targets of MicroRNA ATGCAGT MIR-217 www.broad.mit.e... MIR-217...
Broad TCCAGAG MIR-518C View Gene Set 0.00168 127 0.003357 108 Targets of MicroRNA TCCAGAG MIR-518C www.broad.mit.e... MIR-518C...
Broad CACTGCC MIR-34A MIR-34C MIR-449 View Gene Set 0.001925 249 0.003765 113 Targets of MicroRNA CACTGCC MIR-34A MIR-34C MIR-449 www.broad.mit.e... MIR-34A... MIR-34C... MIR-449...
Broad GTAAGAT MIR-200A View Gene Set 0.002002 44 0.003864 114 Targets of MicroRNA GTAAGAT MIR-200A www.broad.mit.e... MIR-200A...
Broad GTTAAAG MIR-302B View Gene Set 0.002011 58 0.003864 114 Targets of MicroRNA GTTAAAG MIR-302B www.broad.mit.e... MIR-302B...
Broad GTTATAT MIR-410 View Gene Set 0.002056 86 0.003917 116 Targets of MicroRNA GTTATAT MIR-410 www.broad.mit.e... MIR-410...
Broad ATGTCAC MIR-489 View Gene Set 0.0021 76 0.003966 117 Targets of MicroRNA ATGTCAC MIR-489 www.broad.mit.e... MIR-489...
Broad ACACTGG MIR-199A MIR-199B View Gene Set 0.002436 134 0.004514 118 Targets of MicroRNA ACACTGG MIR-199A MIR-199B www.broad.mit.e... MIR-199A... MIR-199B...
Broad ACTGCAG MIR-17-3P View Gene Set 0.002451 88 0.004514 118 Targets of MicroRNA ACTGCAG MIR-17-3P www.broad.mit.e... MIR-17-3P...
Broad GGTGAAG MIR-412 View Gene Set 0.002411 49 0.004514 118 Targets of MicroRNA GGTGAAG MIR-412 www.broad.mit.e... MIR-412...
Broad ACTACCT MIR-196A MIR-196B View Gene Set 0.002555 116 0.004667 121 Targets of MicroRNA ACTACCT MIR-196A MIR-196B www.broad.mit.e... MIR-196A... MIR-196B...
Broad GTAGGCA MIR-189 View Gene Set 0.002714 22 0.004917 122 Targets of MicroRNA GTAGGCA MIR-189 www.broad.mit.e... MIR-189...
Broad AGGAAGC MIR-516-3P View Gene Set 0.002941 92 0.005285 123 Targets of MicroRNA AGGAAGC MIR-516-3P www.broad.mit.e... MIR-516-3P...
Broad TTGGGAG MIR-150 View Gene Set 0.003021 65 0.005385 124 Targets of MicroRNA TTGGGAG MIR-150 www.broad.mit.e... MIR-150...
Broad TAGGTCA MIR-192 MIR-215 View Gene Set 0.003248 37 0.005742 125 Targets of MicroRNA TAGGTCA MIR-192 MIR-215 www.broad.mit.e... MIR-192... MIR-215...
Broad TAGCTTT MIR-9 View Gene Set 0.003308 198 0.005803 126 Targets of MicroRNA TAGCTTT MIR-9 www.broad.mit.e... MIR-9...
Broad GTTTGTT MIR-495 View Gene Set 0.003485 205 0.006016 127 Targets of MicroRNA GTTTGTT MIR-495 www.broad.mit.e... MIR-495...
Broad ACTGCCT MIR-34B View Gene Set 0.003479 190 0.006016 127 Targets of MicroRNA ACTGCCT MIR-34B www.broad.mit.e... MIR-34B...
Broad GGTAACC MIR-409-5P View Gene Set 0.003533 30 0.006053 129 Targets of MicroRNA GGTAACC MIR-409-5P www.broad.mit.e... MIR-409-5P...
Broad CAATGCA MIR-33 View Gene Set 0.003565 85 0.006061 130 Targets of MicroRNA CAATGCA MIR-33 www.broad.mit.e... MIR-33...
Broad ACATATC MIR-190 View Gene Set 0.003725 50 0.006278 131 Targets of MicroRNA ACATATC MIR-190 www.broad.mit.e... MIR-190...
Broad TAGAACC MIR-182 View Gene Set 0.00375 29 0.006278 131 Targets of MicroRNA TAGAACC MIR-182 www.broad.mit.e... MIR-182...
Broad TCTGATA MIR-361 View Gene Set 0.003879 74 0.006445 133 Targets of MicroRNA TCTGATA MIR-361 www.broad.mit.e... MIR-361...
Broad GCGCCTT MIR-525 MIR-524 View Gene Set 0.003933 12 0.00645 134 Targets of MicroRNA GCGCCTT MIR-525 MIR-524 www.broad.mit.e... MIR-525... MIR-524...
Broad AGCATTA MIR-155 View Gene Set 0.00394 118 0.00645 134 Targets of MicroRNA AGCATTA MIR-155 www.broad.mit.e... MIR-155...
Broad ATGAAGG MIR-205 View Gene Set 0.004185 128 0.006801 136 Targets of MicroRNA ATGAAGG MIR-205 www.broad.mit.e... MIR-205...
Broad AGGGCCA MIR-328 View Gene Set 0.004226 66 0.006816 137 Targets of MicroRNA AGGGCCA MIR-328 www.broad.mit.e... MIR-328...
Broad ATTACAT MIR-380-3P View Gene Set 0.004382 87 0.007018 138 Targets of MicroRNA ATTACAT MIR-380-3P www.broad.mit.e... MIR-380-3P...
Broad GGGACCA MIR-133A MIR-133B View Gene Set 0.004693 173 0.007461 139 Targets of MicroRNA GGGACCA MIR-133A MIR-133B www.broad.mit.e... MIR-133A... MIR-133B...
Broad CAGCACT MIR-512-3P View Gene Set 0.005052 134 0.007974 140 Targets of MicroRNA CAGCACT MIR-512-3P www.broad.mit.e... MIR-512-3P...
Broad ACTGAAA MIR-30A-3P MIR-30E-3P View Gene Set 0.005684 165 0.008908 141 Targets of MicroRNA ACTGAAA MIR-30A-3P MIR-30E-3P www.broad.mit.e... MIR-30A-3P... MIR-30E-3P...
Broad ATCATGA MIR-433 View Gene Set 0.006552 94 0.0102 142 Targets of MicroRNA ATCATGA MIR-433 www.broad.mit.e... MIR-433...
Broad GGCAGAC MIR-346 View Gene Set 0.007003 32 0.01082 143 Targets of MicroRNA GGCAGAC MIR-346 www.broad.mit.e... MIR-346...
Broad CTACTGT MIR-199A View Gene Set 0.007572 146 0.01162 144 Targets of MicroRNA CTACTGT MIR-199A www.broad.mit.e... MIR-199A...
Broad TATCTGG MIR-488 View Gene Set 0.007687 49 0.01172 145 Targets of MicroRNA TATCTGG MIR-488 www.broad.mit.e... MIR-488...
Broad ATGTTTC MIR-494 View Gene Set 0.008229 136 0.01246 146 Targets of MicroRNA ATGTTTC MIR-494 www.broad.mit.e... MIR-494...
Broad CTAGGAA MIR-384 View Gene Set 0.008647 53 0.01289 147 Targets of MicroRNA CTAGGAA MIR-384 www.broad.mit.e... MIR-384...
Broad GCAAGAC MIR-431 View Gene Set 0.008652 38 0.01289 147 Targets of MicroRNA GCAAGAC MIR-431 www.broad.mit.e... MIR-431...
Broad ATCTTGC MIR-31 View Gene Set 0.008693 57 0.01289 147 Targets of MicroRNA ATCTTGC MIR-31 www.broad.mit.e... MIR-31...
Broad CAGCAGG MIR-370 View Gene Set 0.009494 128 0.01399 150 Targets of MicroRNA CAGCAGG MIR-370 www.broad.mit.e... MIR-370...
Broad AACATTC MIR-409-3P View Gene Set 0.01055 115 0.01545 151 Targets of MicroRNA AACATTC MIR-409-3P www.broad.mit.e... MIR-409-3P...
Broad AAACCAC MIR-140 View Gene Set 0.01156 90 0.01681 152 Targets of MicroRNA AAACCAC MIR-140 www.broad.mit.e... MIR-140...
Broad ACAACTT MIR-382 View Gene Set 0.01183 64 0.01708 153 Targets of MicroRNA ACAACTT MIR-382 www.broad.mit.e... MIR-382...
Broad AATGGAG MIR-136 View Gene Set 0.0119 62 0.01708 153 Targets of MicroRNA AATGGAG MIR-136 www.broad.mit.e... MIR-136...
Broad AAGTCCA MIR-422B MIR-422A View Gene Set 0.0132 54 0.01882 155 Targets of MicroRNA AAGTCCA MIR-422B MIR-422A www.broad.mit.e... MIR-422B... MIR-422A...
Broad AGTTCTC MIR-146A MIR-146B View Gene Set 0.01388 47 0.01967 156 Targets of MicroRNA AGTTCTC MIR-146A MIR-146B www.broad.mit.e... MIR-146A... MIR-146B...
Broad ACACTCC MIR-122A View Gene Set 0.01468 67 0.02066 157 Targets of MicroRNA ACACTCC MIR-122A www.broad.mit.e... MIR-122A...
Broad CACGTTT MIR-302A View Gene Set 0.01682 24 0.02353 158 Targets of MicroRNA CACGTTT MIR-302A www.broad.mit.e... MIR-302A...
Broad CCTGAGT MIR-510 View Gene Set 0.01711 38 0.02379 159 Targets of MicroRNA CCTGAGT MIR-510 www.broad.mit.e... MIR-510...
Broad AGTCTTA MIR-499 View Gene Set 0.01817 60 0.02509 160 Targets of MicroRNA AGTCTTA MIR-499 www.broad.mit.e... MIR-499...
Broad AGTCAGC MIR-345 View Gene Set 0.01853 52 0.02543 161 Targets of MicroRNA AGTCAGC MIR-345 www.broad.mit.e... MIR-345...
Broad GTGTGAG MIR-342 View Gene Set 0.0196 60 0.02674 162 Targets of MicroRNA GTGTGAG MIR-342 www.broad.mit.e... MIR-342...
Broad GCTGAGT MIR-512-5P View Gene Set 0.02029 48 0.0275 163 Targets of MicroRNA GCTGAGT MIR-512-5P www.broad.mit.e... MIR-512-5P...
Broad TGCAAAC MIR-452 View Gene Set 0.0217 92 0.02925 164 Targets of MicroRNA TGCAAAC MIR-452 www.broad.mit.e... MIR-452...
Broad ACAACCT MIR-453 View Gene Set 0.02274 34 0.03046 165 Targets of MicroRNA ACAACCT MIR-453 www.broad.mit.e... MIR-453...
Broad AGGTGCA MIR-500 View Gene Set 0.02503 79 0.03333 166 Targets of MicroRNA AGGTGCA MIR-500 www.broad.mit.e... MIR-500...
Broad CCAGGTT MIR-490 View Gene Set 0.03041 52 0.04024 167 Targets of MicroRNA CCAGGTT MIR-490 www.broad.mit.e... MIR-490...
Broad CAGGTCC MIR-492 View Gene Set 0.03457 48 0.04547 168 Targets of MicroRNA CAGGTCC MIR-492 www.broad.mit.e... MIR-492...
Broad TGAGATT MIR-216 View Gene Set 0.0359 90 0.04694 169 Targets of MicroRNA TGAGATT MIR-216 www.broad.mit.e... MIR-216...
Broad GTGGTGA MIR-197 View Gene Set 0.03765 60 0.04894 170 Targets of MicroRNA GTGGTGA MIR-197 www.broad.mit.e... MIR-197...

Gene Set Collection: Broad.c3.TFT

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad SCGGAAGY_V$ELK1_02 View Gene Set 9.804e-18 784 6.029e-15 1 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SCGGAAGY which matches annotation for ELK1: ELK1 member of ETS oncogene family www.broad.mit.e...
Broad GGGCGGR_V$SP1_Q6 View Gene Set 6.789e-17 2120 2.088e-14 2 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGGCGGR which matches annotation for SP1: Sp1 transcription factor www.broad.mit.e...
Broad V$E2F_Q4_01 View Gene Set 1.865e-12 171 3.823e-10 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCSCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad GCCATNTTG_V$YY1_Q6 View Gene Set 1.361e-11 289 2.093e-09 4 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTG which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad RCGCANGCGY_V$NRF1_Q6 View Gene Set 1.717e-11 580 2.112e-09 5 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RCGCANGCGY which matches annotation for NRF1: nuclear respiratory factor 1 www.broad.mit.e...
Broad GATTGGY_V$NFY_Q6_01 View Gene Set 1.154e-10 830 1.183e-08 6 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GATTGGY. Motif does not match any known transcription factor www.broad.mit.e...
Broad MGGAAGTG_V$GABP_B View Gene Set 1.729e-10 512 1.519e-08 7 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif MGGAAGTG which matches annotation for GABPA: GA binding protein transcription factor alpha subunit 60kDa<br> GABPB2: GA binding protein transcription factor beta subunit 2 www.broad.mit.e...
Broad V$E2F_Q4 View Gene Set 1.413e-08 166 9.657e-07 8 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1_Q6_01 View Gene Set 1.316e-08 177 9.657e-07 8 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTTCGCGCS which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F_Q6 View Gene Set 2.04e-08 165 1.255e-06 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1_Q4 View Gene Set 7.374e-08 178 3.951e-06 11 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTSGCGG which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F_Q3_01 View Gene Set 7.709e-08 171 3.951e-06 11 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$YY1_Q6 View Gene Set 1.456e-07 166 6.889e-06 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTN which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad V$E2F_Q6_01 View Gene Set 1.574e-07 167 6.917e-06 14 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKCGCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$USF_01 View Gene Set 2.297e-07 186 9.417e-06 15 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNRYCACGTGRYNN. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1_Q4_01 View Gene Set 3.645e-07 167 1.401e-05 16 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F_03 View Gene Set 5.68e-07 171 2.055e-05 17 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGCGMNR. Motif does not match any known transcription factor www.broad.mit.e...
Broad ACTAYRNNNCCCR_UNKNOWN View Gene Set 6.601e-07 293 2.255e-05 18 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ACTAYRNNNCCCR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1DP1RB_01 View Gene Set 7.139e-07 168 2.311e-05 19 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) www.broad.mit.e...
Broad V$E2F1_Q3 View Gene Set 9.865e-07 176 3.033e-05 20 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKTSSCGC which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F_Q3 View Gene Set 1.254e-06 162 3.673e-05 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTCGCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad GCGNNANTTCC_UNKNOWN View Gene Set 1.363e-06 85 3.809e-05 22 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GCGNNANTTCC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1_Q6 View Gene Set 1.453e-06 167 3.887e-05 23 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGS which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad TCCCRNNRTGC_UNKNOWN View Gene Set 2.225e-06 130 5.7e-05 24 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TCCCRNNRTGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad KCCGNSWTTT_UNKNOWN View Gene Set 2.752e-06 76 6.769e-05 25 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KCCGNSWTTT. Motif does not match any known transcription factor www.broad.mit.e...
Broad GTGACGY_V$E4F1_Q6 View Gene Set 3.109e-06 462 7.353e-05 26 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GTGACGY which matches annotation for E4F1: E4F transcription factor 1 www.broad.mit.e...
Broad V$ARNT_01 View Gene Set 5.789e-06 196 0.0001319 27 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NDDNNCACGTGNNNNN which matches annotation for ARNT: aryl hydrocarbon receptor nuclear translocator www.broad.mit.e...
Broad ACAWNRNSRCGG_UNKNOWN View Gene Set 6.589e-06 50 0.0001447 28 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ACAWNRNSRCGG. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$NFMUE1_Q6 View Gene Set 6.906e-06 175 0.0001465 29 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CGGCCATCT. Motif does not match any known transcription factor www.broad.mit.e...
Broad MCAATNNNNNGCG_UNKNOWN View Gene Set 8.021e-06 62 0.0001644 30 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif MCAATNNNNNGCG. Motif does not match any known transcription factor www.broad.mit.e...
Broad CACGTG_V$MYC_Q2 View Gene Set 9.958e-06 734 0.0001975 31 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CACGTG which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian) www.broad.mit.e...
Broad V$E2F_02 View Gene Set 1.041e-05 169 0.0002001 32 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$YY1_02 View Gene Set 1.383e-05 168 0.0002577 33 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNCGGCCATCTTGNCTSNW which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad V$E2F1DP1_01 View Gene Set 1.85e-05 169 0.0003161 34 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1DP2_01 View Gene Set 1.85e-05 169 0.0003161 34 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) www.broad.mit.e...
Broad V$E2F4DP2_01 View Gene Set 1.85e-05 169 0.0003161 34 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) www.broad.mit.e...
Broad V$E2F4DP1_01 View Gene Set 3.298e-05 174 0.0005337 37 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F_Q2 View Gene Set 3.255e-05 120 0.0005337 37 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$USF_Q6 View Gene Set 3.496e-05 178 0.0005513 39 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GYCACGTGNC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$NRF2_01 View Gene Set 3.943e-05 166 0.0006062 40 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif ACCGGAAGNG which matches annotation for GABPB1: GA binding protein transcription factor beta subunit 1. www.broad.mit.e...
Broad KTGGYRSGAA_UNKNOWN View Gene Set 4.086e-05 53 0.0006129 41 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KTGGYRSGAA. Motif does not match any known transcription factor www.broad.mit.e...
Broad AAGWWRNYGGC_UNKNOWN View Gene Set 4.281e-05 85 0.0006269 42 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif AAGWWRNYGGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad TAANNYSGCG_UNKNOWN View Gene Set 4.713e-05 60 0.000674 43 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TAANNYSGCG. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$GABP_B View Gene Set 5.115e-05 162 0.0007149 44 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif VCCGGAAGNGCR which matches annotation for GABPA: GA binding protein transcription factor alpha subunit 60kDa<br> GABPB2: GA binding protein transcription factor beta subunit 2 www.broad.mit.e...
Broad GKCGCNNNNNNNTGAYG_UNKNOWN View Gene Set 6.216e-05 41 0.0008496 45 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GKCGCNNNNNNNTGAYG. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$FREAC2_01 View Gene Set 9.3e-05 196 0.001243 46 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNANNGTAAACAANNN which matches annotation for FOXF2: forkhead box F2 www.broad.mit.e...
Broad V$MAX_01 View Gene Set 0.0001132 194 0.001473 47 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNANCACGTGNTNN which matches annotation for MAX: MYC associated factor X www.broad.mit.e...
Broad CTTTGT_V$LEF1_Q2 View Gene Set 0.000115 1458 0.001473 47 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CTTTGT which matches annotation for LEF1: lymphoid enhancer-binding factor 1 www.broad.mit.e...
Broad V$SREBP1_01 View Gene Set 0.0001341 133 0.001683 49 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NATCACGTGAY which matches annotation for SREBF1: sterol regulatory element binding transcription factor 1 www.broad.mit.e...
Broad SGCGSSAAA_V$E2F1DP2_01 View Gene Set 0.0001474 122 0.001813 50 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SGCGSSAAA which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) www.broad.mit.e...
Broad YGCGYRCGC_UNKNOWN View Gene Set 0.0001598 207 0.001927 51 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif YGCGYRCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$ELK1_02 View Gene Set 0.0001635 170 0.001934 52 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNCCGGAARTNN which matches annotation for ELK1: ELK1 member of ETS oncogene family www.broad.mit.e...
Broad TTGTTT_V$FOXO4_01 View Gene Set 0.0001712 1507 0.001987 53 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTGTTT which matches annotation for MLLT7: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog Drosophila); translocated to 7 www.broad.mit.e...
Broad V$P300_01 View Gene Set 0.0001933 182 0.002161 54 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNGGGAGTNNNNS which matches annotation for PCAF: p300/CBP-associated factor www.broad.mit.e...
Broad GGAMTNNNNNTCCY_UNKNOWN View Gene Set 0.0001931 85 0.002161 54 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGAMTNNNNNTCCY. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$SOX9_B1 View Gene Set 0.0002151 183 0.002363 56 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNAACAATRGNN which matches annotation for SOX9: SRY (sex determining region Y)-box 9 (campomelic dysplasia autosomal sex-reversal) www.broad.mit.e...
Broad V$NFY_Q6_01 View Gene Set 0.0002571 185 0.002774 57 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNNNRRCCAATSR. Motif does not match any known transcription factor www.broad.mit.e...
Broad CGTSACG_V$PAX3_B View Gene Set 0.0003446 99 0.003654 58 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CGTSACG which matches annotation for PAX3: paired box gene 3 (Waardenburg syndrome 1) www.broad.mit.e...
Broad RGAANNTTC_V$HSF1_01 View Gene Set 0.0003533 326 0.003683 59 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RGAANNTTC which matches annotation for HSF1: heat shock transcription factor 1 www.broad.mit.e...
Broad RRCCGTTA_UNKNOWN View Gene Set 0.0004114 53 0.004217 60 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif RRCCGTTA. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF_Q6_01 View Gene Set 0.0004235 168 0.004225 61 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NRCCACGTGASN. Motif does not match any known transcription factor www.broad.mit.e...
Broad TGCGCANK_UNKNOWN View Gene Set 0.000426 361 0.004225 61 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TGCGCANK. Motif does not match any known transcription factor www.broad.mit.e...
Broad ATGGYGGA_UNKNOWN View Gene Set 0.0004382 68 0.004278 63 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ATGGYGGA. Motif does not match any known transcription factor www.broad.mit.e...
Broad GGGNRMNNYCAT_UNKNOWN View Gene Set 0.0004796 61 0.004609 64 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGGNRMNNYCAT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$NFY_01 View Gene Set 0.000492 178 0.004655 65 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNNRRCCAATSRGNNN. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$ELK1_01 View Gene Set 0.0005013 187 0.004661 66 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NAAACMGGAAGTNCVH which matches annotation for ELK1: ELK1 member of ETS oncogene family www.broad.mit.e...
Broad TCCATTKW_UNKNOWN View Gene Set 0.0005078 181 0.004661 66 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TCCATTKW. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1_Q3_01 View Gene Set 0.0006207 188 0.005614 68 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTGGCGCGRAANNGNM which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$CMYB_01 View Gene Set 0.0006401 179 0.005705 69 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCNRNNGRCNGTTGGKGG which matches annotation for MYB: v-myb myeloblastosis viral oncogene homolog (avian) www.broad.mit.e...
Broad V$FOXO4_02 View Gene Set 0.0007869 190 0.006721 70 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNGTTGTTTACNTN which matches annotation for MLLT7: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog Drosophila); translocated to 7 www.broad.mit.e...
Broad TMTCGCGANR_UNKNOWN View Gene Set 0.0007836 100 0.006721 70 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TMTCGCGANR. Motif does not match any known transcription factor www.broad.mit.e...
Broad RTAAACA_V$FREAC2_01 View Gene Set 0.0007791 697 0.006721 70 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RTAAACA which matches annotation for FOXF2: forkhead box F2 www.broad.mit.e...
Broad GGCNKCCATNK_UNKNOWN View Gene Set 0.001012 84 0.008529 73 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGCNKCCATNK. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MAF_Q6 View Gene Set 0.001132 202 0.009407 74 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TRGRRGGAAGTKKSST which matches annotation for MAF: v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) www.broad.mit.e...
Broad V$USF_02 View Gene Set 0.001234 197 0.01012 75 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNRNCACGTGNYNN. Motif does not match any known transcription factor www.broad.mit.e...
Broad TTGCWCAAY_V$CEBPB_02 View Gene Set 0.001282 49 0.01037 76 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTGCWCAAY which matches annotation for CEBPB: CCAAT/enhancer binding protein (C/EBP) beta www.broad.mit.e...
Broad V$CETS1P54_01 View Gene Set 0.001384 183 0.01106 77 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCMGGAWGYN which matches annotation for ETS1: v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) www.broad.mit.e...
Broad AACYNNNNTTCCS_UNKNOWN View Gene Set 0.001521 65 0.01199 78 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif AACYNNNNTTCCS. Motif does not match any known transcription factor www.broad.mit.e...
Broad CCAATNNSNNNGCG_UNKNOWN View Gene Set 0.001604 45 0.01249 79 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CCAATNNSNNNGCG. Motif does not match any known transcription factor www.broad.mit.e...
Broad GGGYGTGNY_UNKNOWN View Gene Set 0.0017 487 0.01307 80 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGGYGTGNY. Motif does not match any known transcription factor www.broad.mit.e...
Broad GATGKMRGCG_UNKNOWN View Gene Set 0.001781 47 0.01352 81 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GATGKMRGCG. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$AP2_Q6_01 View Gene Set 0.001841 181 0.0138 82 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SNNNCCNCAGGCN which matches annotation for GTF3A: general transcription factor IIIA www.broad.mit.e...
Broad V$AR_01 View Gene Set 0.002089 106 0.01548 83 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGTACANNRTGTTCT which matches annotation for AR: androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) www.broad.mit.e...
Broad V$TAXCREB_01 View Gene Set 0.002158 103 0.0158 84 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGGGGTTGACGYANA. Motif does not match any known transcription factor www.broad.mit.e...
Broad WGTTNNNNNAAA_UNKNOWN View Gene Set 0.002287 414 0.01655 85 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif WGTTNNNNNAAA. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$ARNT_02 View Gene Set 0.002574 179 0.01841 86 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNRTCACGTGAYNNNNN which matches annotation for ARNT: aryl hydrocarbon receptor nuclear translocator www.broad.mit.e...
Broad V$SP1_Q6_01 View Gene Set 0.002641 163 0.01867 87 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGGGCGGGGC which matches annotation for SP1: Sp1 transcription factor www.broad.mit.e...
Broad V$ATF4_Q2 View Gene Set 0.002683 188 0.01875 88 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CVTGACGYMABG which matches annotation for ATF4: activating transcription factor 4 (tax-responsive enhancer element B67) www.broad.mit.e...
Broad V$YY1_01 View Gene Set 0.003063 190 0.02116 89 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNCCATNTWNNNWN which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad V$EFC_Q6 View Gene Set 0.003202 210 0.02188 90 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif MGTTACYAGGCAAM which matches annotation for RFX1: regulatory factor X 1 (influences HLA class II expression) www.broad.mit.e...
Broad V$FOXO4_01 View Gene Set 0.003321 184 0.02244 91 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RWAAACAANNN which matches annotation for MLLT7: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog Drosophila); translocated to 7 www.broad.mit.e...
Broad CCCNNNNNNAAGWT_UNKNOWN View Gene Set 0.003463 74 0.02315 92 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CCCNNNNNNAAGWT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$WHN_B View Gene Set 0.003598 186 0.02379 93 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif ANNGACGCTNN which matches annotation for FOXN1: forkhead box N1 www.broad.mit.e...
Broad V$HSF1_01 View Gene Set 0.003816 195 0.0247 94 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif AGAANRTTCN which matches annotation for HSF1: heat shock transcription factor 1 www.broad.mit.e...
Broad TTCNRGNNNNTTC_V$HSF_Q6 View Gene Set 0.003789 111 0.0247 94 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTCNRGNNNNTTC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF2_Q6 View Gene Set 0.003861 182 0.02474 96 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CASGYG. Motif does not match any known transcription factor www.broad.mit.e...
Broad AACTTT_UNKNOWN View Gene Set 0.004047 1437 0.02566 97 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif AACTTT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E4F1_Q6 View Gene Set 0.004105 203 0.02576 98 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SYTACGTCAC which matches annotation for E4F1: E4F transcription factor 1 www.broad.mit.e...
Broad V$CREB_02 View Gene Set 0.004529 185 0.02813 99 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNGNTGACGTNN which matches annotation for CREB1: cAMP responsive element binding protein 1 www.broad.mit.e...
Broad V$NFY_C View Gene Set 0.004754 179 0.02924 100 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NCTGATTGGYTASY. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$NRF1_Q6 View Gene Set 0.005184 151 0.03157 101 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CGCATGCGCR which matches annotation for NRF1: nuclear respiratory factor 1 www.broad.mit.e...
Broad V$AP2_Q6 View Gene Set 0.005415 188 0.03233 102 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif MKCCCSCNGGCG which matches annotation for GTF3A: general transcription factor IIIA www.broad.mit.e...
Broad V$P53_DECAMER_Q2 View Gene Set 0.005366 199 0.03233 102 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RGRCAWGNCY which matches annotation for TP53: tumor protein p53 (Li-Fraumeni syndrome) www.broad.mit.e...
Broad V$CREB_01 View Gene Set 0.005505 198 0.03255 104 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TGACGTMA which matches annotation for CREB1: cAMP responsive element binding protein 1 www.broad.mit.e...
Broad GGCNRNWCTTYS_UNKNOWN View Gene Set 0.005594 52 0.03277 105 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGCNRNWCTTYS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$HSF2_01 View Gene Set 0.005788 181 0.03358 106 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NGAANNWTCK which matches annotation for HSF2: heat shock transcription factor 2 www.broad.mit.e...
Broad V$PAX5_01 View Gene Set 0.006189 115 0.03557 107 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif BCNNNRNGCANBGNTGNRTAGCSGCHNB which matches annotation for PAX5: paired box gene 5 (B-cell lineage specific activator) www.broad.mit.e...
Broad RRAGTTGT_UNKNOWN View Gene Set 0.006257 180 0.03563 108 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif RRAGTTGT. Motif does not match any known transcription factor www.broad.mit.e...
Broad CCGNMNNTNACG_UNKNOWN View Gene Set 0.006464 56 0.03647 109 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CCGNMNNTNACG. Motif does not match any known transcription factor www.broad.mit.e...
Broad TTCYRGAA_UNKNOWN View Gene Set 0.006698 221 0.03745 110 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTCYRGAA. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$PAX3_B View Gene Set 0.006929 65 0.03839 111 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNNCGTCACGSTYNNNNN which matches annotation for PAX3: paired box gene 3 (Waardenburg syndrome 1) www.broad.mit.e...
Broad V$E2F_01 View Gene Set 0.007664 55 0.04188 112 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TWSGCGCGAAAAYKR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$FOXO3_01 View Gene Set 0.007695 177 0.04188 112 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TNNTTGTTTACNTW which matches annotation for FOXO3A: forkhead box O3A www.broad.mit.e...
Broad V$MYC_Q2 View Gene Set 0.00829 135 0.04453 114 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CACGTGS which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian) www.broad.mit.e...
Broad V$AR_03 View Gene Set 0.008327 48 0.04453 114 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNNRGNACRNNGTGTTCTNNNNNN which matches annotation for AR: androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) www.broad.mit.e...
Broad V$FOXD3_01 View Gene Set 0.00883 162 0.04649 116 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NAWTGTTTRTTT which matches annotation for FOXD3: forkhead box D3 www.broad.mit.e...
Broad V$ETS2_B View Gene Set 0.008942 210 0.04649 116 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif KRCAGGAARTRNKT which matches annotation for ETS2: v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) www.broad.mit.e...
Broad V$STAT1_02 View Gene Set 0.008866 179 0.04649 116 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CANTTCCS which matches annotation for STAT1: signal transducer and activator of transcription 1 91kDa www.broad.mit.e...
Broad KMCATNNWGGA_UNKNOWN View Gene Set 0.008996 60 0.04649 116 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KMCATNNWGGA. Motif does not match any known transcription factor www.broad.mit.e...

Gene Set Collection: Broad.c4.CGN

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad GNF2_CCNA2 View Gene Set 1.4e-19 62 2.989e-17 1 Neighborhood of CCNA2 www.broad.mit.e...
Broad GNF2_SMC4L1 View Gene Set 1.185e-19 75 2.989e-17 1 Neighborhood of SMC4L1 www.broad.mit.e...
Broad GNF2_PCNA View Gene Set 7.466e-19 62 1.063e-16 3 Neighborhood of PCNA www.broad.mit.e...
Broad GNF2_CCNB2 View Gene Set 1.549e-17 53 1.653e-15 4 Neighborhood of CCNB2 www.broad.mit.e...
Broad GNF2_CDC20 View Gene Set 2.326e-17 52 1.986e-15 5 Neighborhood of CDC20 www.broad.mit.e...
Broad GNF2_RRM1 View Gene Set 3.269e-17 82 2.327e-15 6 Neighborhood of RRM1 www.broad.mit.e...
Broad MORF_HDAC2 View Gene Set 4.168e-16 256 2.543e-14 7 Neighborhood of HDAC2 www.broad.mit.e...
Broad GNF2_CDC2 View Gene Set 1.661e-15 56 8.866e-14 8 Neighborhood of CDC2 www.broad.mit.e...
Broad GNF2_HMMR View Gene Set 2.082e-15 43 9.879e-14 9 Neighborhood of HMMR www.broad.mit.e...
Broad GNF2_CENPF View Gene Set 8.421e-15 56 3.596e-13 10 Neighborhood of CENPF www.broad.mit.e...
Broad GNF2_BUB1B View Gene Set 1.089e-12 46 4.228e-11 11 Neighborhood of BUB1B www.broad.mit.e...
Broad GNF2_CKS2 View Gene Set 1.329e-12 45 4.384e-11 12 Neighborhood of CKS2 www.broad.mit.e...
Broad GNF2_DEK View Gene Set 1.335e-12 45 4.384e-11 12 Neighborhood of DEK www.broad.mit.e...
Broad GNF2_RFC4 View Gene Set 6.358e-12 57 1.939e-10 14 Neighborhood of RFC4 www.broad.mit.e...
Broad MORF_RFC4 View Gene Set 9.633e-12 137 2.285e-10 15 Neighborhood of RFC4 www.broad.mit.e...
Broad GNF2_FEN1 View Gene Set 9.3e-12 49 2.285e-10 15 Neighborhood of FEN1 www.broad.mit.e...
Broad GNF2_MCM5 View Gene Set 8.588e-12 51 2.285e-10 15 Neighborhood of MCM5 www.broad.mit.e...
Broad GNF2_TTK View Gene Set 8.356e-12 34 2.285e-10 15 Neighborhood of TTK www.broad.mit.e...
Broad GNF2_PA2G4 View Gene Set 1.411e-11 73 3.171e-10 19 Neighborhood of PA2G4 www.broad.mit.e...
Broad GNF2_MCM4 View Gene Set 1.615e-11 50 3.449e-10 20 Neighborhood of MCM4 www.broad.mit.e...
Broad MORF_RAD23A View Gene Set 2.405e-11 316 4.89e-10 21 Neighborhood of RAD23A www.broad.mit.e...
Broad MORF_GNB1 View Gene Set 4.242e-11 276 8.057e-10 22 Neighborhood of GNB1 www.broad.mit.e...
Broad GNF2_RRM2 View Gene Set 4.34e-11 36 8.057e-10 22 Neighborhood of RRM2 www.broad.mit.e...
Broad GCM_MYST2 View Gene Set 2.333e-10 138 4.15e-09 24 Neighborhood of MYST2 www.broad.mit.e...
Broad MORF_PPP1CC View Gene Set 2.769e-10 150 4.729e-09 25 Neighborhood of PPP1CC www.broad.mit.e...
Broad GNF2_KPNB1 View Gene Set 7.657e-10 52 1.257e-08 26 Neighborhood of KPNB1 www.broad.mit.e...
Broad MORF_BUB3 View Gene Set 8.081e-10 256 1.278e-08 27 Neighborhood of BUB3 www.broad.mit.e...
Broad GNF2_CENPE View Gene Set 8.621e-10 37 1.315e-08 28 Neighborhood of CENPE www.broad.mit.e...
Broad GNF2_ESPL1 View Gene Set 9.341e-10 35 1.375e-08 29 Neighborhood of ESPL1 www.broad.mit.e...
Broad MORF_DNMT1 View Gene Set 2.378e-09 105 3.385e-08 30 Neighborhood of DNMT1 www.broad.mit.e...
Broad GNF2_HDAC1 View Gene Set 2.782e-09 85 3.832e-08 31 Neighborhood of HDAC1 www.broad.mit.e...
Broad GNF2_H2AFX View Gene Set 3.665e-09 28 4.89e-08 32 Neighborhood of H2AFX www.broad.mit.e...
Broad GCM_RAN View Gene Set 5.322e-09 160 6.8e-08 33 Neighborhood of RAN www.broad.mit.e...
Broad GNF2_MKI67 View Gene Set 5.415e-09 26 6.8e-08 33 Neighborhood of MKI67 www.broad.mit.e...
Broad GCM_ZNF198 View Gene Set 8.604e-09 98 1.05e-07 35 Neighborhood of ZNF198 www.broad.mit.e...
Broad MORF_PRKDC View Gene Set 9.858e-09 173 1.169e-07 36 Neighborhood of PRKDC www.broad.mit.e...
Broad GCM_RAB10 View Gene Set 1.147e-08 143 1.324e-07 37 Neighborhood of RAB10 www.broad.mit.e...
Broad MORF_REV3L View Gene Set 1.898e-08 52 2.133e-07 38 Neighborhood of REV3L www.broad.mit.e...
Broad MORF_CCNF View Gene Set 2.283e-08 65 2.499e-07 39 Neighborhood of CCNF www.broad.mit.e...
Broad MORF_HAT1 View Gene Set 3.021e-08 155 3.225e-07 40 Neighborhood of HAT1 www.broad.mit.e...
Broad MORF_BUB1B View Gene Set 3.919e-08 61 4.081e-07 41 Neighborhood of BUB1B www.broad.mit.e...
Broad GNF2_HAT1 View Gene Set 4.167e-08 45 4.237e-07 42 Neighborhood of HAT1 www.broad.mit.e...
Broad MORF_BUB1 View Gene Set 5.669e-08 49 5.629e-07 43 Neighborhood of BUB1 www.broad.mit.e...
Broad MORF_XRCC5 View Gene Set 6.902e-08 210 6.698e-07 44 Neighborhood of XRCC5 www.broad.mit.e...
Broad GCM_UBE2N View Gene Set 1.102e-07 125 1.046e-06 45 Neighborhood of UBE2N www.broad.mit.e...
Broad GNF2_SMC2L1 View Gene Set 1.272e-07 30 1.181e-06 46 Neighborhood of SMC2L1 www.broad.mit.e...
Broad GNF2_RFC3 View Gene Set 1.964e-07 38 1.784e-06 47 Neighborhood of RFC3 www.broad.mit.e...
Broad MORF_DEK View Gene Set 2.233e-07 229 1.987e-06 48 Neighborhood of DEK www.broad.mit.e...
Broad GCM_MLL View Gene Set 4.185e-07 130 3.647e-06 49 Neighborhood of MLL www.broad.mit.e...
Broad MORF_RRM1 View Gene Set 4.834e-07 90 4.128e-06 50 Neighborhood of RRM1 www.broad.mit.e...
Broad GCM_MAP4K4 View Gene Set 5.631e-07 144 4.624e-06 51 Neighborhood of MAP4K4 www.broad.mit.e...
Broad GNF2_APEX1 View Gene Set 5.61e-07 72 4.624e-06 51 Neighborhood of APEX1 www.broad.mit.e...
Broad MORF_PTPN11 View Gene Set 6.696e-07 93 5.354e-06 53 Neighborhood of PTPN11 www.broad.mit.e...
Broad GNF2_BUB1 View Gene Set 6.77e-07 25 5.354e-06 53 Neighborhood of BUB1 www.broad.mit.e...
Broad MORF_UBE2N View Gene Set 8.017e-07 79 6.113e-06 55 Neighborhood of UBE2N www.broad.mit.e...
Broad GNF2_ELAC2 View Gene Set 7.955e-07 32 6.113e-06 55 Neighborhood of ELAC2 www.broad.mit.e...
Broad GCM_GSPT1 View Gene Set 9.41e-07 129 6.928e-06 57 Neighborhood of GSPT1 www.broad.mit.e...
Broad GNF2_CKS1B View Gene Set 9.316e-07 36 6.928e-06 57 Neighborhood of CKS1B www.broad.mit.e...
Broad GNF2_MLH1 View Gene Set 1.13e-06 36 8.181e-06 59 Neighborhood of MLH1 www.broad.mit.e...
Broad GNF2_MSH2 View Gene Set 1.223e-06 26 8.701e-06 60 Neighborhood of MSH2 www.broad.mit.e...
Broad GCM_NCAM1 View Gene Set 1.346e-06 111 9.356e-06 61 Neighborhood of NCAM1 www.broad.mit.e...
Broad GNF2_XRCC5 View Gene Set 1.358e-06 61 9.356e-06 61 Neighborhood of XRCC5 www.broad.mit.e...
Broad GCM_NF2 View Gene Set 1.719e-06 235 1.165e-05 63 Neighborhood of NF2 www.broad.mit.e...
Broad GCM_BMPR2 View Gene Set 1.79e-06 68 1.194e-05 64 Neighborhood of BMPR2 www.broad.mit.e...
Broad MORF_ATRX View Gene Set 1.917e-06 185 1.245e-05 65 Neighborhood of ATRX www.broad.mit.e...
Broad GNF2_ANP32B View Gene Set 1.924e-06 29 1.245e-05 65 Neighborhood of ANP32B www.broad.mit.e...
Broad MORF_CDC10 View Gene Set 2.032e-06 120 1.295e-05 67 Neighborhood of CDC10 www.broad.mit.e...
Broad MORF_RPA2 View Gene Set 2.204e-06 170 1.384e-05 68 Neighborhood of RPA2 www.broad.mit.e...
Broad MORF_SMC1L1 View Gene Set 2.582e-06 47 1.553e-05 69 Neighborhood of SMC1L1 www.broad.mit.e...
Broad MORF_PRKAG1 View Gene Set 2.58e-06 202 1.553e-05 69 Neighborhood of PRKAG1 www.broad.mit.e...
Broad MORF_SNRP70 View Gene Set 2.536e-06 50 1.553e-05 69 Neighborhood of SNRP70 www.broad.mit.e...
Broad MORF_EIF4E View Gene Set 2.851e-06 76 1.691e-05 72 Neighborhood of EIF4E www.broad.mit.e...
Broad GNF2_RAN View Gene Set 2.952e-06 78 1.727e-05 73 Neighborhood of RAN www.broad.mit.e...
Broad GCM_RBM8A View Gene Set 3.058e-06 64 1.764e-05 74 Neighborhood of RBM8A www.broad.mit.e...
Broad MORF_AATF View Gene Set 3.93e-06 179 2.237e-05 75 Neighborhood of AATF www.broad.mit.e...
Broad MORF_CDC16 View Gene Set 4.231e-06 67 2.353e-05 76 Neighborhood of CDC16 www.broad.mit.e...
Broad GCM_DFFA View Gene Set 4.242e-06 100 2.353e-05 76 Neighborhood of DFFA www.broad.mit.e...
Broad GCM_HBP1 View Gene Set 4.804e-06 54 2.63e-05 78 Neighborhood of HBP1 www.broad.mit.e...
Broad GCM_PTK2 View Gene Set 5.091e-06 126 2.751e-05 79 Neighborhood of PTK2 www.broad.mit.e...
Broad GNF2_TDG View Gene Set 6.936e-06 23 3.702e-05 80 Neighborhood of TDG www.broad.mit.e...
Broad MORF_RAD54L View Gene Set 9.81e-06 94 5.135e-05 81 Neighborhood of RAD54L www.broad.mit.e...
Broad GCM_CALM1 View Gene Set 9.862e-06 91 5.135e-05 81 Neighborhood of CALM1 www.broad.mit.e...
Broad MORF_RAB11A View Gene Set 1.393e-05 53 7.165e-05 83 Neighborhood of RAB11A www.broad.mit.e...
Broad MORF_TERF2IP View Gene Set 1.426e-05 99 7.249e-05 84 Neighborhood of TERF2IP www.broad.mit.e...
Broad MORF_FEN1 View Gene Set 1.486e-05 58 7.465e-05 85 Neighborhood of FEN1 www.broad.mit.e...
Broad MORF_TPR View Gene Set 1.815e-05 131 9.009e-05 86 Neighborhood of TPR www.broad.mit.e...
Broad MORF_PPP2CA View Gene Set 1.922e-05 110 9.434e-05 87 Neighborhood of PPP2CA www.broad.mit.e...
Broad MORF_RFC1 View Gene Set 2.05e-05 98 9.941e-05 88 Neighborhood of RFC1 www.broad.mit.e...
Broad GNF2_DENR View Gene Set 2.094e-05 39 9.941e-05 88 Neighborhood of DENR www.broad.mit.e...
Broad GNF2_RBBP6 View Gene Set 2.095e-05 54 9.941e-05 88 Neighborhood of RBBP6 www.broad.mit.e...
Broad MORF_EI24 View Gene Set 2.399e-05 136 0.0001126 91 Neighborhood of EI24 www.broad.mit.e...
Broad GNF2_RPA1 View Gene Set 2.805e-05 20 0.0001302 92 Neighborhood of RPA1 www.broad.mit.e...
Broad MORF_RAB1A View Gene Set 2.932e-05 179 0.0001346 93 Neighborhood of RAB1A www.broad.mit.e...
Broad MORF_DDB1 View Gene Set 3.117e-05 220 0.0001416 94 Neighborhood of DDB1 www.broad.mit.e...
Broad MORF_RAD21 View Gene Set 3.765e-05 157 0.0001692 95 Neighborhood of RAD21 www.broad.mit.e...
Broad MORF_ESPL1 View Gene Set 3.863e-05 58 0.0001718 96 Neighborhood of ESPL1 www.broad.mit.e...
Broad MORF_ACP1 View Gene Set 4.144e-05 178 0.0001824 97 Neighborhood of ACP1 www.broad.mit.e...
Broad MORF_PSMC2 View Gene Set 5.043e-05 100 0.0002197 98 Neighborhood of PSMC2 www.broad.mit.e...
Broad MORF_RAP1A View Gene Set 5.413e-05 122 0.0002335 99 Neighborhood of RAP1A www.broad.mit.e...
Broad GCM_CRKL View Gene Set 5.892e-05 50 0.0002516 100 Neighborhood of CRKL www.broad.mit.e...
Broad GCM_SUFU View Gene Set 8.196e-05 62 0.0003465 101 Neighborhood of SUFU www.broad.mit.e...
Broad MORF_PPP2R5E View Gene Set 9.229e-05 76 0.0003863 102 Neighborhood of PPP2R5E www.broad.mit.e...
Broad MORF_SOD1 View Gene Set 0.0001085 247 0.0004499 103 Neighborhood of SOD1 www.broad.mit.e...
Broad GNF2_SMC1L1 View Gene Set 0.0001279 24 0.0005251 104 Neighborhood of SMC1L1 www.broad.mit.e...
Broad GCM_CSNK1A1 View Gene Set 0.0001463 28 0.0005948 105 Neighborhood of CSNK1A1 www.broad.mit.e...
Broad MORF_SP3 View Gene Set 0.0001893 69 0.0007485 106 Neighborhood of SP3 www.broad.mit.e...
Broad MORF_PAPSS1 View Gene Set 0.000188 98 0.0007485 106 Neighborhood of PAPSS1 www.broad.mit.e...
Broad GCM_DEAF1 View Gene Set 0.0001887 23 0.0007485 106 Neighborhood of DEAF1 www.broad.mit.e...
Broad MORF_PPP6C View Gene Set 0.0001998 88 0.0007827 109 Neighborhood of PPP6C www.broad.mit.e...
Broad GCM_TPR View Gene Set 0.000213 29 0.0008268 110 Neighborhood of TPR www.broad.mit.e...
Broad MORF_GSPT1 View Gene Set 0.0002303 41 0.0008859 111 Neighborhood of GSPT1 www.broad.mit.e...
Broad MORF_UNG View Gene Set 0.0002613 65 0.0009963 112 Neighborhood of UNG www.broad.mit.e...
Broad GCM_DLG1 View Gene Set 0.0003308 63 0.00125 113 Neighborhood of DLG1 www.broad.mit.e...
Broad MORF_EIF3S2 View Gene Set 0.0003859 220 0.001445 114 Neighborhood of EIF3S2 www.broad.mit.e...
Broad GCM_MAX View Gene Set 0.0004488 28 0.001666 115 Neighborhood of MAX www.broad.mit.e...
Broad MORF_RAF1 View Gene Set 0.0004816 94 0.001773 116 Neighborhood of RAF1 www.broad.mit.e...
Broad MORF_BECN1 View Gene Set 0.0005065 93 0.001848 117 Neighborhood of BECN1 www.broad.mit.e...
Broad MORF_HDAC1 View Gene Set 0.0005329 222 0.001912 118 Neighborhood of HDAC1 www.broad.mit.e...
Broad MORF_BMI1 View Gene Set 0.0005294 71 0.001912 118 Neighborhood of BMI1 www.broad.mit.e...
Broad GCM_GSTA4 View Gene Set 0.0005409 57 0.001925 120 Neighborhood of GSTA4 www.broad.mit.e...
Broad MORF_XPC View Gene Set 0.000604 55 0.002132 121 Neighborhood of XPC www.broad.mit.e...
Broad MORF_RAC1 View Gene Set 0.0007552 196 0.002643 122 Neighborhood of RAC1 www.broad.mit.e...
Broad MORF_TERF1 View Gene Set 0.0008179 57 0.002839 123 Neighborhood of TERF1 www.broad.mit.e...
Broad GNF2_PPP6C View Gene Set 0.0008787 33 0.003026 124 Neighborhood of PPP6C www.broad.mit.e...
Broad MORF_IKBKG View Gene Set 0.0009949 119 0.003399 125 Neighborhood of IKBKG www.broad.mit.e...
Broad GCM_PPM1D View Gene Set 0.001082 22 0.003666 126 Neighborhood of PPM1D www.broad.mit.e...
Broad GNF2_JAK1 View Gene Set 0.001138 28 0.003828 127 Neighborhood of JAK1 www.broad.mit.e...
Broad GCM_NUMA1 View Gene Set 0.001184 45 0.00395 128 Neighborhood of NUMA1 www.broad.mit.e...
Broad GCM_MAP1B View Gene Set 0.001215 55 0.004023 129 Neighborhood of MAP1B www.broad.mit.e...
Broad MORF_PCNA View Gene Set 0.001229 71 0.004036 130 Neighborhood of PCNA www.broad.mit.e...
Broad MORF_MBD4 View Gene Set 0.001248 76 0.004068 131 Neighborhood of MBD4 www.broad.mit.e...
Broad MORF_MSH2 View Gene Set 0.001374 52 0.004443 132 Neighborhood of MSH2 www.broad.mit.e...
Broad MORF_SKP1A View Gene Set 0.00155 175 0.004978 133 Neighborhood of SKP1A www.broad.mit.e...
Broad MORF_RAB5A View Gene Set 0.001599 83 0.005096 134 Neighborhood of RAB5A www.broad.mit.e...
Broad MORF_PHB View Gene Set 0.001623 112 0.005117 135 Neighborhood of PHB www.broad.mit.e...
Broad MORF_SS18 View Gene Set 0.00163 55 0.005117 135 Neighborhood of SS18 www.broad.mit.e...
Broad GNF2_INPP5D View Gene Set 0.001664 38 0.005185 137 Neighborhood of INPP5D www.broad.mit.e...
Broad GCM_RAP2A View Gene Set 0.001852 30 0.005731 138 Neighborhood of RAP2A www.broad.mit.e...
Broad MORF_PSMF1 View Gene Set 0.002011 151 0.006101 139 Neighborhood of PSMF1 www.broad.mit.e...
Broad GCM_ING1 View Gene Set 0.002015 50 0.006101 139 Neighborhood of ING1 www.broad.mit.e...
Broad GNF2_G22P1 View Gene Set 0.002013 29 0.006101 139 Neighborhood of G22P1 www.broad.mit.e...
Broad GNF2_CBFB View Gene Set 0.002114 26 0.006356 142 Neighborhood of CBFB www.broad.mit.e...
Broad GCM_ERBB2IP View Gene Set 0.002154 57 0.006432 143 Neighborhood of ERBB2IP www.broad.mit.e...
Broad MORF_CTBP1 View Gene Set 0.0022 149 0.006523 144 Neighborhood of CTBP1 www.broad.mit.e...
Broad GCM_RAD21 View Gene Set 0.002289 30 0.00674 145 Neighborhood of RAD21 www.broad.mit.e...
Broad GNF2_BUB3 View Gene Set 0.002383 22 0.006969 146 Neighborhood of BUB3 www.broad.mit.e...
Broad MORF_RPA1 View Gene Set 0.002534 55 0.00736 147 Neighborhood of RPA1 www.broad.mit.e...
Broad GCM_DDX5 View Gene Set 0.002625 52 0.007574 148 Neighborhood of DDX5 www.broad.mit.e...
Broad MORF_PPP5C View Gene Set 0.003243 81 0.009233 149 Neighborhood of PPP5C www.broad.mit.e...
Broad GNF2_DDX5 View Gene Set 0.003242 54 0.009233 149 Neighborhood of DDX5 www.broad.mit.e...
Broad GCM_DENR View Gene Set 0.003334 40 0.009429 151 Neighborhood of DENR www.broad.mit.e...
Broad GNF2_LYN View Gene Set 0.003505 26 0.009846 152 Neighborhood of LYN www.broad.mit.e...
Broad MORF_CSNK1D View Gene Set 0.004262 65 0.01189 153 Neighborhood of CSNK1D www.broad.mit.e...
Broad MORF_DEAF1 View Gene Set 0.00456 54 0.01264 154 Neighborhood of DEAF1 www.broad.mit.e...
Broad GCM_CSNK1D View Gene Set 0.005342 24 0.01472 155 Neighborhood of CSNK1D www.broad.mit.e...
Broad MORF_CUL1 View Gene Set 0.006006 62 0.01644 156 Neighborhood of CUL1 www.broad.mit.e...
Broad GNF2_BNIP3L View Gene Set 0.006074 62 0.01652 157 Neighborhood of BNIP3L www.broad.mit.e...
Broad MORF_PSMC1 View Gene Set 0.007354 162 0.01987 158 Neighborhood of PSMC1 www.broad.mit.e...
Broad MORF_BRCA1 View Gene Set 0.008705 242 0.02332 159 Neighborhood of BRCA1 www.broad.mit.e...
Broad MORF_GMPS View Gene Set 0.008738 48 0.02332 159 Neighborhood of GMPS www.broad.mit.e...
Broad MORF_PRKAR1A View Gene Set 0.008862 133 0.0235 161 Neighborhood of PRKAR1A www.broad.mit.e...
Broad MORF_CDC2L5 View Gene Set 0.009238 127 0.0242 162 Neighborhood of CDC2L5 www.broad.mit.e...
Broad MORF_MTA1 View Gene Set 0.009212 95 0.0242 162 Neighborhood of MTA1 www.broad.mit.e...
Broad MORF_PRKACA View Gene Set 0.009428 104 0.02455 164 Neighborhood of PRKACA www.broad.mit.e...
Broad GCM_IL6ST View Gene Set 0.009733 48 0.02519 165 Neighborhood of IL6ST www.broad.mit.e...
Broad GCM_PTPRD View Gene Set 0.01086 50 0.02793 166 Neighborhood of PTPRD www.broad.mit.e...
Broad MORF_BAG5 View Gene Set 0.01114 48 0.02817 167 Neighborhood of BAG5 www.broad.mit.e...
Broad MORF_RFC5 View Gene Set 0.0112 69 0.02817 167 Neighborhood of RFC5 www.broad.mit.e...
Broad GNF2_MSH6 View Gene Set 0.01122 30 0.02817 167 Neighborhood of MSH6 www.broad.mit.e...
Broad GNF2_RAD23A View Gene Set 0.01116 61 0.02817 167 Neighborhood of RAD23A www.broad.mit.e...
Broad MORF_AP3D1 View Gene Set 0.01248 119 0.03117 171 Neighborhood of AP3D1 www.broad.mit.e...
Broad GCM_CHUK View Gene Set 0.01258 61 0.03124 172 Neighborhood of CHUK www.broad.mit.e...
Broad GCM_BAG5 View Gene Set 0.01363 26 0.03364 173 Neighborhood of BAG5 www.broad.mit.e...
Broad GCM_CBFB View Gene Set 0.01462 59 0.03588 174 Neighborhood of CBFB www.broad.mit.e...
Broad GNF2_STAT6 View Gene Set 0.01486 75 0.03626 175 Neighborhood of STAT6 www.broad.mit.e...
Broad MORF_CSNK2B View Gene Set 0.01547 256 0.03752 176 Neighborhood of CSNK2B www.broad.mit.e...
Broad MORF_RAB6A View Gene Set 0.01571 63 0.03789 177 Neighborhood of RAB6A www.broad.mit.e...
Broad MORF_FANCG View Gene Set 0.0163 148 0.0391 178 Neighborhood of FANCG www.broad.mit.e...
Broad GNF2_SPTA1 View Gene Set 0.01664 75 0.03969 179 Neighborhood of SPTA1 www.broad.mit.e...
Broad MORF_PTEN View Gene Set 0.01716 80 0.04072 180 Neighborhood of PTEN www.broad.mit.e...
Broad MORF_PRDX3 View Gene Set 0.01732 79 0.04086 181 Neighborhood of PRDX3 www.broad.mit.e...
Broad MORF_MSH3 View Gene Set 0.01862 226 0.04369 182 Neighborhood of MSH3 www.broad.mit.e...
Broad MORF_ERCC2 View Gene Set 0.02039 91 0.04744 183 Neighborhood of ERCC2 www.broad.mit.e...
Broad GCM_BECN1 View Gene Set 0.02044 59 0.04744 183 Neighborhood of BECN1 www.broad.mit.e...
Broad MORF_RAD23B View Gene Set 0.02104 159 0.04855 185 Neighborhood of RAD23B www.broad.mit.e...

Gene Set Collection: Broad.c4.CM

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad module_98 View Gene Set 6.038e-22 375 2.741e-19 1 Genes in module_98 www.broad.mit.e...
Broad module_198 View Gene Set 9.998e-20 288 1.513e-17 2 Genes in module_198 www.broad.mit.e...
Broad module_252 View Gene Set 8.326e-20 224 1.513e-17 2 Genes in module_252 www.broad.mit.e...
Broad module_3 View Gene Set 1.195e-16 374 1.356e-14 4 Genes in module_3 www.broad.mit.e...
Broad module_54 View Gene Set 1.503e-15 242 1.365e-13 5 Genes in module_54 www.broad.mit.e...
Broad module_17 View Gene Set 1.458e-14 351 1.103e-12 6 Genes in module_17 www.broad.mit.e...
Broad module_8 View Gene Set 2.135e-14 403 1.385e-12 7 Genes in module_8 www.broad.mit.e...
Broad module_197 View Gene Set 1.667e-12 170 9.462e-11 8 Genes in module_197 www.broad.mit.e...
Broad module_18 View Gene Set 2.03e-12 434 1.024e-10 9 Genes in module_18 www.broad.mit.e...
Broad module_72 View Gene Set 5.037e-12 293 2.287e-10 10 Genes in module_72 www.broad.mit.e...
Broad module_124 View Gene Set 7.876e-10 92 3.251e-08 11 Genes in module_124 www.broad.mit.e...
Broad module_15 View Gene Set 1.288e-08 347 4.874e-07 12 Genes in module_15 www.broad.mit.e...
Broad module_244 View Gene Set 2.068e-07 182 7.223e-06 13 Genes in module_244 www.broad.mit.e...
Broad module_36 View Gene Set 2.463e-07 146 7.989e-06 14 Genes in module_36 www.broad.mit.e...
Broad module_57 View Gene Set 3.018e-07 54 9.134e-06 15 Genes in module_57 www.broad.mit.e...
Broad module_352 View Gene Set 3.421e-07 17 9.707e-06 16 Genes in module_352 www.broad.mit.e...
Broad module_320 View Gene Set 3.722e-07 19 9.939e-06 17 Genes in module_320 www.broad.mit.e...
Broad module_105 View Gene Set 7.43e-07 192 1.874e-05 18 Genes in module_105 www.broad.mit.e...
Broad module_183 View Gene Set 1.278e-06 52 3.054e-05 19 Genes in module_183 www.broad.mit.e...
Broad module_52 View Gene Set 4.119e-06 415 9.35e-05 20 Genes in module_52 www.broad.mit.e...
Broad module_126 View Gene Set 1.101e-05 173 0.000238 21 Genes in module_126 www.broad.mit.e...
Broad module_358 View Gene Set 1.45e-05 72 0.0002991 22 Genes in module_358 www.broad.mit.e...
Broad module_261 View Gene Set 4.293e-05 91 0.0008324 23 Genes in module_261 www.broad.mit.e...
Broad module_321 View Gene Set 4.584e-05 107 0.0008324 23 Genes in module_321 www.broad.mit.e...
Broad module_332 View Gene Set 4.494e-05 35 0.0008324 23 Genes in module_332 www.broad.mit.e...
Broad module_182 View Gene Set 0.0002387 94 0.004168 26 Genes in module_182 www.broad.mit.e...
Broad module_16 View Gene Set 0.0005141 495 0.008644 27 Genes in module_16 www.broad.mit.e...
Broad module_451 View Gene Set 0.0006234 29 0.01011 28 Genes in module_451 www.broad.mit.e...
Broad module_278 View Gene Set 0.0008761 34 0.01326 29 Genes in module_278 www.broad.mit.e...
Broad module_356 View Gene Set 0.0008598 141 0.01326 29 Genes in module_356 www.broad.mit.e...
Broad module_53 View Gene Set 0.00101 389 0.01434 31 Genes in module_53 www.broad.mit.e...
Broad module_337 View Gene Set 0.001005 59 0.01434 31 Genes in module_337 www.broad.mit.e...
Broad module_325 View Gene Set 0.001261 46 0.01699 33 Genes in module_325 www.broad.mit.e...
Broad module_493 View Gene Set 0.001272 60 0.01699 33 Genes in module_493 www.broad.mit.e...
Broad module_195 View Gene Set 0.001579 138 0.02048 35 Genes in module_195 www.broad.mit.e...
Broad module_97 View Gene Set 0.001689 91 0.02124 36 Genes in module_97 www.broad.mit.e...
Broad module_308 View Gene Set 0.001731 66 0.02124 36 Genes in module_308 www.broad.mit.e...
Broad module_403 View Gene Set 0.001983 44 0.02369 38 Genes in module_403 www.broad.mit.e...
Broad module_525 View Gene Set 0.002157 61 0.02511 39 Genes in module_525 www.broad.mit.e...
Broad module_4 View Gene Set 0.002234 21 0.02513 40 Genes in module_4 www.broad.mit.e...
Broad module_432 View Gene Set 0.002269 15 0.02513 40 Genes in module_432 www.broad.mit.e...
Broad module_239 View Gene Set 0.002371 112 0.02562 42 Genes in module_239 www.broad.mit.e...
Broad module_82 View Gene Set 0.002591 24 0.02736 43 Genes in module_82 www.broad.mit.e...
Broad module_177 View Gene Set 0.002658 101 0.02742 44 Genes in module_177 www.broad.mit.e...
Broad module_315 View Gene Set 0.003418 15 0.03404 45 Genes in module_315 www.broad.mit.e...
Broad module_456 View Gene Set 0.003449 108 0.03404 45 Genes in module_456 www.broad.mit.e...
Broad module_503 View Gene Set 0.003891 106 0.03758 47 Genes in module_503 www.broad.mit.e...

Gene Set Collection: Broad.c5.BP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 3.278e-30 1197 2.704e-27 1 Genes annotated by the GO term GO:0006139. The chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad BIOPOLYMER_METABOLIC_PROCESS View Gene Set 2.076e-26 1623 8.565e-24 2 Genes annotated by the GO term GO:0043283. The chemical reactions and pathways involving biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. www.broad.mit.e...
Broad RNA_METABOLIC_PROCESS View Gene Set 1.742e-23 801 4.791e-21 3 Genes annotated by the GO term GO:0016070. The chemical reactions and pathways involving RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. www.broad.mit.e...
Broad TRANSCRIPTION View Gene Set 2.185e-14 738 3.605e-12 4 Genes annotated by the GO term GO:0006350. The synthesis of either RNA on a template of DNA or DNA on a template of RNA. www.broad.mit.e...
Broad TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 1.951e-14 449 3.605e-12 4 Genes annotated by the GO term GO:0006366. The synthesis of RNA from a DNA template by RNA polymerase II (Pol II) originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). www.broad.mit.e...
Broad RNA_BIOSYNTHETIC_PROCESS View Gene Set 5.021e-14 625 6.903e-12 6 Genes annotated by the GO term GO:0032774. The chemical reactions and pathways resulting in the formation of RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. www.broad.mit.e...
Broad TRANSCRIPTION_DNA_DEPENDENT View Gene Set 8.011e-14 623 9.442e-12 7 Genes annotated by the GO term GO:0006351. The synthesis of RNA on a template of DNA. www.broad.mit.e...
Broad REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 2.149e-13 601 2.216e-11 8 Genes annotated by the GO term GO:0019219. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 3.823e-13 285 3.323e-11 9 Genes annotated by the GO term GO:0006357. Any process that modulates the frequency rate or extent of transcription from an RNA polymerase II promoter. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTION View Gene Set 4.028e-13 555 3.323e-11 9 Genes annotated by the GO term GO:0045449. Any process that modulates the frequency rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. www.broad.mit.e...
Broad CELL_CYCLE_GO_0007049 View Gene Set 6.103e-13 304 4.577e-11 11 Genes annotated by the GO term GO:0007049. The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. www.broad.mit.e...
Broad RNA_PROCESSING View Gene Set 1.337e-12 147 8.487e-11 12 Genes annotated by the GO term GO:0006396. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. www.broad.mit.e...
Broad REGULATION_OF_RNA_METABOLIC_PROCESS View Gene Set 1.326e-12 457 8.487e-11 12 Genes annotated by the GO term GO:0051252. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving RNA. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT View Gene Set 1.839e-12 452 1.084e-10 14 Genes annotated by the GO term GO:0006355. Any process that modulates the frequency rate or extent of DNA-dependent transcription. www.broad.mit.e...
Broad REGULATION_OF_CELLULAR_METABOLIC_PROCESS View Gene Set 9.579e-12 767 5.268e-10 15 Genes annotated by the GO term GO:0031323. Any process that modulates the frequency rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. www.broad.mit.e...
Broad REGULATION_OF_METABOLIC_PROCESS View Gene Set 4.258e-11 779 2.196e-09 16 Genes annotated by the GO term GO:0019222. Any process that modulates the frequency rate or extent of the chemical reactions and pathways within a cell or an organism. www.broad.mit.e...
Broad REGULATION_OF_GENE_EXPRESSION View Gene Set 5.995e-11 660 2.91e-09 17 Genes annotated by the GO term GO:0010468. Any process that modulates the frequency rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. www.broad.mit.e...
Broad CELL_CYCLE_PROCESS View Gene Set 1.049e-09 187 4.81e-08 18 Genes annotated by the GO term GO:0022402. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. www.broad.mit.e...
Broad MITOTIC_CELL_CYCLE View Gene Set 5.578e-09 148 2.422e-07 19 Genes annotated by the GO term GO:0000278. Progression through the phases of the mitotic cell cycle the most common eukaryotic cell cycle which canonically comprises four successive phases called G1 S G2 and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division or G1 and G2 phases may be absent. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_TRANSCRIPTION View Gene Set 2.39e-08 185 9.861e-07 20 Genes annotated by the GO term GO:0016481. Any process that stops prevents or reduces the frequency rate or extent of transcription. www.broad.mit.e...
Broad CELL_CYCLE_PHASE View Gene Set 2.781e-08 167 1.092e-06 21 Genes annotated by the GO term GO:0022403. A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. www.broad.mit.e...
Broad M_PHASE View Gene Set 4.456e-08 111 1.671e-06 22 Genes annotated by the GO term GO:0000279. Progression through M phase the part of the cell cycle comprising nuclear division. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 4.726e-08 205 1.695e-06 23 Genes annotated by the GO term GO:0045934. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad RNA_SPLICING View Gene Set 7.817e-08 73 2.588e-06 24 Genes annotated by the GO term GO:0008380. The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. www.broad.mit.e...
Broad M_PHASE_OF_MITOTIC_CELL_CYCLE View Gene Set 7.841e-08 83 2.588e-06 24 Genes annotated by the GO term GO:0000087. Progression through M phase the part of the mitotic cell cycle during which mitosis takes place. www.broad.mit.e...
Broad MITOSIS View Gene Set 1.682e-07 81 5.339e-06 26 Genes annotated by the GO term GO:0007067. Progression through mitosis the division of the eukaryotic cell nucleus to produce two daughter nuclei that usually contain the identical chromosome complement to their mother. www.broad.mit.e...
Broad DNA_METABOLIC_PROCESS View Gene Set 4.04e-07 253 1.234e-05 27 Genes annotated by the GO term GO:0006259. The chemical reactions and pathways involving DNA deoxyribonucleic acid one of the two main types of nucleic acid consisting of a long unbranched macromolecule formed from one or more commonly two strands of linked deoxyribonucleotides. www.broad.mit.e...
Broad ORGANELLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 5.003e-07 458 1.474e-05 28 Genes annotated by the GO term GO:0006996. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of any organelle within a cell. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS View Gene Set 5.5e-07 252 1.513e-05 29 Genes annotated by the GO term GO:0031324. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. www.broad.mit.e...
Broad REGULATION_OF_CELL_CYCLE View Gene Set 5.342e-07 176 1.513e-05 29 Genes annotated by the GO term GO:0051726. Any process that modulates the rate or extent of progression through the cell cycle. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_TRANSCRIPTION_DNA_DEPENDENT View Gene Set 1.25e-06 127 3.223e-05 31 Genes annotated by the GO term GO:0045892. Any process that stops prevents or reduces the frequency rate or extent of DNA-dependent transcription. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_RNA_METABOLIC_PROCESS View Gene Set 1.25e-06 127 3.223e-05 31 Genes annotated by the GO term GO:0051253. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways involving RNA. www.broad.mit.e...
Broad INTRACELLULAR_TRANSPORT View Gene Set 2.042e-06 271 5.104e-05 33 Genes annotated by the GO term GO:0046907. The directed movement of substances within a cell. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_METABOLIC_PROCESS View Gene Set 2.238e-06 255 5.43e-05 34 Genes annotated by the GO term GO:0009892. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways within a cell or an organism. www.broad.mit.e...
Broad CELLULAR_PROTEIN_CATABOLIC_PROCESS View Gene Set 2.838e-06 58 6.689e-05 35 Genes annotated by the GO term GO:0044257. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_CELLULAR_PROCESS View Gene Set 3.46e-06 629 7.929e-05 36 Genes annotated by the GO term GO:0048523. Any process that stops prevents or reduces the frequency rate or extent of cellular processes those that are carried out at the cellular level but are not necessarily restricted to a single cell. For example cell communication occurs among more than one cell but occurs at the cellular level. www.broad.mit.e...
Broad MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS View Gene Set 4.854e-06 34 0.0001082 37 Genes annotated by the GO term GO:0000226. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. www.broad.mit.e...
Broad DNA_REPLICATION View Gene Set 5.359e-06 101 0.0001163 38 Genes annotated by the GO term GO:0006260. The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. www.broad.mit.e...
Broad RESPONSE_TO_DNA_DAMAGE_STIMULUS View Gene Set 1.425e-05 159 0.0003014 39 Genes annotated by the GO term GO:0006974. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. www.broad.mit.e...
Broad MRNA_METABOLIC_PROCESS View Gene Set 2.297e-05 70 0.0004621 40 Genes annotated by the GO term GO:0016071. The chemical reactions and pathways involving mRNA messenger RNA which is responsible for carrying the coded genetic 'message' transcribed from DNA to sites of protein assembly at the ribosomes. www.broad.mit.e...
Broad CHROMOSOME_ORGANIZATION_AND_BIOGENESIS View Gene Set 2.283e-05 117 0.0004621 40 Genes annotated by the GO term GO:0051276. A process that is carried out at the cellular level that results in the formation arrangement of constituent parts or disassembly of chromosomes structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. www.broad.mit.e...
Broad MICROTUBULE_BASED_PROCESS View Gene Set 2.428e-05 80 0.000477 42 Genes annotated by the GO term GO:0007017. Any cellular process that depends upon or alters the microtubule cytoskeleton that part of the cytoskeleton comprising microtubules and their associated proteins. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY View Gene Set 2.744e-05 74 0.0005264 43 Genes annotated by the GO term GO:0022613. The cellular process by which a complex containing RNA and proteins is synthesized aggregates and bonds together. www.broad.mit.e...
Broad PROTEIN_CATABOLIC_PROCESS View Gene Set 3.026e-05 68 0.0005673 44 Genes annotated by the GO term GO:0030163. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native active configuration with or without the hydrolysis of peptide bonds. www.broad.mit.e...
Broad ESTABLISHMENT_OF_CELLULAR_LOCALIZATION View Gene Set 4.232e-05 342 0.000764 45 Genes annotated by the GO term GO:0051649. The directed movement of a substance or cellular entity such as a protein complex or organelle to a specific location within or in the membrane of a cell. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS View Gene Set 4.26e-05 659 0.000764 45 Genes annotated by the GO term GO:0048519. Any process that stops prevents or reduces the frequency rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression protein modification or interaction with a protein or substrate molecule. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT View Gene Set 4.484e-05 115 0.0007871 47 Genes annotated by the GO term GO:0045893. Any process that activates or increases the frequency rate or extent of DNA-dependent transcription. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS View Gene Set 5.005e-05 117 0.0008602 48 Genes annotated by the GO term GO:0051254. Any process that activates or increases the frequency rate or extent of the chemical reactions and pathways involving RNA. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 5.954e-05 65 0.001002 49 Genes annotated by the GO term GO:0045944. Any process that activates or increases the frequency rate or extent of transcription from the RNA polymerase II promoter. www.broad.mit.e...
Broad RESPONSE_TO_ENDOGENOUS_STIMULUS View Gene Set 6.128e-05 197 0.001011 50 Genes annotated by the GO term GO:0009719. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of an endogenous stimulus. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_TRANSCRIPTION View Gene Set 6.442e-05 139 0.001042 51 Genes annotated by the GO term GO:0045941. Any process that activates or increases the frequency rate or extent of transcription. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 6.707e-05 83 0.001064 52 Genes annotated by the GO term GO:0000122. Any process that stops prevents or reduces the frequency rate or extent of transcription from an RNA polymerase II promoter. www.broad.mit.e...
Broad PROTEIN_RNA_COMPLEX_ASSEMBLY View Gene Set 9.281e-05 59 0.001445 53 Genes annotated by the GO term GO:0022618. The aggregation arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX_ASSEMBLY View Gene Set 0.0001102 271 0.001684 54 Genes annotated by the GO term GO:0065003. The aggregation arrangement and bonding together of a set of macromolecules to form a complex. www.broad.mit.e...
Broad CHROMOSOME_SEGREGATION View Gene Set 0.0001199 31 0.001798 55 Genes annotated by the GO term GO:0007059. The process by which genetic material in the form of chromosomes is organized and then physically separated and apportioned to two or more sets. www.broad.mit.e...
Broad MRNA_PROCESSING_GO_0006397 View Gene Set 0.0001301 59 0.001917 56 Genes annotated by the GO term GO:0006397. Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 0.0001697 149 0.002456 57 Genes annotated by the GO term GO:0045935. Any process that activates or increases the frequency rate or extent of the chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad CELLULAR_COMPONENT_ASSEMBLY View Gene Set 0.0001928 288 0.002743 58 Genes annotated by the GO term GO:0022607. A cellular process that results in the assembly of a part of the cell. www.broad.mit.e...
Broad CELLULAR_LOCALIZATION View Gene Set 0.0002125 360 0.002972 59 Genes annotated by the GO term GO:0051641. The processes by which a substance or cellular entity such as a protein complex or organelle is transported to and/or maintained in a specific location within or in the membrane of a cell. www.broad.mit.e...
Broad DNA_DEPENDENT_DNA_REPLICATION View Gene Set 0.0002214 55 0.003044 60 Genes annotated by the GO term GO:0006261. The process whereby new strands of DNA are synthesized using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. www.broad.mit.e...
Broad PROGRAMMED_CELL_DEATH View Gene Set 0.0002785 424 0.003647 61 Genes annotated by the GO term GO:0012501. Cell death resulting from activation of endogenous cellular processes. www.broad.mit.e...
Broad STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY View Gene Set 0.0002755 20 0.003647 61 Genes annotated by the GO term GO:0030518. Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor. www.broad.mit.e...
Broad INTRACELLULAR_RECEPTOR_MEDIATED_SIGNALING_PATHWAY View Gene Set 0.0002755 21 0.003647 61 Genes annotated by the GO term GO:0030522. Any series of molecular signals initiated by a ligand entering the target cell where it binds to an intracellular receptor. www.broad.mit.e...
Broad CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS View Gene Set 0.0003257 103 0.004199 64 Genes annotated by the GO term GO:0044265. The chemical reactions and pathways resulting in the breakdown of a macromolecule any large molecule including proteins nucleic acids and carbohydrates as carried out by individual cells. www.broad.mit.e...
Broad APOPTOSIS_GO View Gene Set 0.0003339 423 0.004238 65 Genes annotated by the GO term GO:0006915. A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. www.broad.mit.e...
Broad REGULATION_OF_GENE_EXPRESSION_EPIGENETIC View Gene Set 0.0003906 30 0.004883 66 Genes annotated by the GO term GO:0040029. Any process that modulates the frequency rate or extent of gene expression; the process is mitotically or meiotically heritable or is stably self-propagated in the cytoplasm of a resting cell and does not entail a change in DNA sequence. www.broad.mit.e...
Broad BIOPOLYMER_MODIFICATION View Gene Set 0.0004112 627 0.005064 67 Genes annotated by the GO term GO:0043412. The covalent alteration of one or more monomeric units in a polypeptide polynucleotide polysaccharide or other biological polymer resulting in a change in its properties. www.broad.mit.e...
Broad MITOTIC_SPINDLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0004726 9 0.005734 68 Genes annotated by the GO term GO:0007052. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the microtubule spindle during a mitotic cell cycle. www.broad.mit.e...
Broad REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0005391 124 0.006445 69 Genes annotated by the GO term GO:0051128. Any process that modulates the frequency rate or extent of the processes involved in the formation arrangement of constituent parts or disassembly of cell structures including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. www.broad.mit.e...
Broad NUCLEAR_TRANSPORT View Gene Set 0.0006338 84 0.007262 70 Genes annotated by the GO term GO:0051169. The directed movement of substances into out of or within the nucleus. www.broad.mit.e...
Broad TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 0.0006272 29 0.007262 70 Genes annotated by the GO term GO:0006367. Processes involved in starting transcription from the RNA polymerase II promoter. www.broad.mit.e...
Broad NUCLEOCYTOPLASMIC_TRANSPORT View Gene Set 0.0006338 83 0.007262 70 Genes annotated by the GO term GO:0006913. The directed movement of molecules between the nucleus and the cytoplasm. www.broad.mit.e...
Broad TRANSCRIPTION_INITIATION View Gene Set 0.000646 35 0.007301 73 Genes annotated by the GO term GO:0006352. Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter. www.broad.mit.e...
Broad MITOTIC_SISTER_CHROMATID_SEGREGATION View Gene Set 0.0007815 16 0.008713 74 Genes annotated by the GO term GO:0000070. The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome composed of two sister chromatids aligns at the cell equator paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. www.broad.mit.e...
Broad DNA_INTEGRITY_CHECKPOINT View Gene Set 0.0008707 23 0.009578 75 Genes annotated by the GO term GO:0031570. Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure. www.broad.mit.e...
Broad TRANSLATIONAL_INITIATION View Gene Set 0.001009 39 0.01096 76 Genes annotated by the GO term GO:0006413. The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome mRNA and an initiation complex that contains the first aminoacyl-tRNA. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS View Gene Set 0.001096 214 0.01175 77 Genes annotated by the GO term GO:0051094. Any process that activates or increases the rate or extent of development the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). www.broad.mit.e...
Broad ANDROGEN_RECEPTOR_SIGNALING_PATHWAY View Gene Set 0.001127 12 0.01192 78 Genes annotated by the GO term GO:0030521. Any series of molecular signals generated as a consequence of an androgen binding to its receptor. www.broad.mit.e...
Broad DNA_REPAIR View Gene Set 0.001145 123 0.01196 79 Genes annotated by the GO term GO:0006281. The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations chemical mutagens fungal and bacterial toxins etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal base excision repair nucleotide excision repair photoreactivation bypass double-strand break repair pathway and mismatch repair pathway. www.broad.mit.e...
Broad REGULATION_OF_PROGRAMMED_CELL_DEATH View Gene Set 0.001344 336 0.01386 80 Genes annotated by the GO term GO:0043067. Any process that modulates the frequency rate or extent of programmed cell death cell death resulting from activation of endogenous cellular processes. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_CELLULAR_PROCESS View Gene Set 0.001454 644 0.01481 81 Genes annotated by the GO term GO:0048522. Any process that activates or increases the frequency rate or extent of cellular processes those that are carried out at the cellular level but are not necessarily restricted to a single cell. For example cell communication occurs among more than one cell but occurs at the cellular level. www.broad.mit.e...
Broad CELL_CYCLE_CHECKPOINT_GO_0000075 View Gene Set 0.001494 47 0.01503 82 Genes annotated by the GO term GO:0000075. A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. www.broad.mit.e...
Broad PROTEIN_MODIFICATION_PROCESS View Gene Set 0.00152 610 0.01511 83 Genes annotated by the GO term GO:0006464. The covalent alteration of one or more amino acids occurring in proteins peptides and nascent polypeptides (co-translational post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). www.broad.mit.e...
Broad INTRACELLULAR_PROTEIN_TRANSPORT View Gene Set 0.001615 138 0.0155 84 Genes annotated by the GO term GO:0006886. The directed movement of proteins in a cell including the movement of proteins between specific compartments or structures within a cell such as organelles of a eukaryotic cell. www.broad.mit.e...
Broad DNA_DAMAGE_RESPONSESIGNAL_TRANSDUCTION View Gene Set 0.001603 34 0.0155 84 Genes annotated by the GO term GO:0042770. A cascade of processes induced by the detection of DNA damage within a cell. www.broad.mit.e...
Broad REGULATION_OF_APOPTOSIS View Gene Set 0.001608 335 0.0155 84 Genes annotated by the GO term GO:0042981. Any process that modulates the occurrence or rate of cell death by apoptosis. www.broad.mit.e...
Broad CELLULAR_PROTEIN_METABOLIC_PROCESS View Gene Set 0.001656 1085 0.0157 87 Genes annotated by the GO term GO:0044267. The chemical reactions and pathways involving a specific protein rather than of proteins in general occurring at the level of an individual cell. Includes protein modification. www.broad.mit.e...
Broad POST_TRANSLATIONAL_PROTEIN_MODIFICATION View Gene Set 0.001761 462 0.01651 88 Genes annotated by the GO term GO:0043687. The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome. www.broad.mit.e...
Broad PROTEIN_TRANSPORT View Gene Set 0.001809 150 0.01677 89 Genes annotated by the GO term GO:0015031. The directed movement of proteins into out of within or between cells. www.broad.mit.e...
Broad PEROXISOME_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.001855 15 0.01697 90 Genes annotated by the GO term GO:0007031. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a peroxisome. www.broad.mit.e...
Broad VACUOLAR_TRANSPORT View Gene Set 0.001912 14 0.01697 90 Genes annotated by the GO term GO:0007034. The directed movement of substances into out of or within a vacuole. www.broad.mit.e...
Broad ENDOSOME_TRANSPORT View Gene Set 0.001887 23 0.01697 90 Genes annotated by the GO term GO:0016197. The directed movement of substances into out of or mediated by an endosome a membrane-bound organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation. www.broad.mit.e...
Broad INTRACELLULAR_SIGNALING_CASCADE View Gene Set 0.0019 648 0.01697 90 Genes annotated by the GO term GO:0007242. A series of reactions within the cell that occur as a result of a single trigger reaction or compound. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_GROWTH View Gene Set 0.00236 38 0.02049 94 Genes annotated by the GO term GO:0045926. Any process that stops prevents or reduces the rate or extent of growth the increase in size or mass of all or part of an organism. www.broad.mit.e...
Broad PROTEIN_METABOLIC_PROCESS View Gene Set 0.00234 1198 0.02049 94 Genes annotated by the GO term GO:0019538. The chemical reactions and pathways involving a specific protein rather than of proteins in general. Includes protein modification. www.broad.mit.e...
Broad PROTEIN_DNA_COMPLEX_ASSEMBLY View Gene Set 0.002398 48 0.02061 96 Genes annotated by the GO term GO:0065004. The aggregation arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex. www.broad.mit.e...
Broad BIOPOLYMER_CATABOLIC_PROCESS View Gene Set 0.002457 115 0.02069 97 Genes annotated by the GO term GO:0043285. The chemical reactions and pathways resulting in the breakdown of biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. www.broad.mit.e...
Broad PROTEIN_TARGETING View Gene Set 0.002443 103 0.02069 97 Genes annotated by the GO term GO:0006605. The process of targeting specific proteins to particular membrane-bound subcellular organelles. Usually requires an organelle specific protein sequence motif. www.broad.mit.e...
Broad SISTER_CHROMATID_SEGREGATION View Gene Set 0.002546 17 0.02122 99 Genes annotated by the GO term GO:0000819. The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets. www.broad.mit.e...
Broad COFACTOR_METABOLIC_PROCESS View Gene Set 0.002594 53 0.0214 100 Genes annotated by the GO term GO:0051186. The chemical reactions and pathways involving a cofactor a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic such as the metal atoms zinc iron and copper in certain forms or organic in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. www.broad.mit.e...
Broad PROTEIN_IMPORT View Gene Set 0.002762 59 0.02234 101 Genes annotated by the GO term GO:0017038. The directed movement of proteins into a cell or organelle. www.broad.mit.e...
Broad REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY View Gene Set 0.002736 42 0.02234 101 Genes annotated by the GO term GO:0000079. Any process that modulates the frequency rate or extent of CDK activity. www.broad.mit.e...
Broad RIBONUCLEOTIDE_METABOLIC_PROCESS View Gene Set 0.002829 14 0.02266 103 Genes annotated by the GO term GO:0009259. The chemical reactions and pathways involving a ribonucleotide a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS View Gene Set 0.002903 222 0.02303 104 Genes annotated by the GO term GO:0031325. Any process that activates or increases the frequency rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. www.broad.mit.e...
Broad SPINDLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.002981 10 0.02342 105 Genes annotated by the GO term GO:0007051. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the spindle the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_BIOLOGICAL_PROCESS View Gene Set 0.003024 685 0.02354 106 Genes annotated by the GO term GO:0048518. Any process that activates or increases the frequency rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression protein modification or interaction with a protein or substrate molecule. www.broad.mit.e...
Broad PROTEIN_KINASE_CASCADE View Gene Set 0.003069 282 0.02367 107 Genes annotated by the GO term GO:0007243. A series of reactions mediated by protein kinases which occurs as a result of a single trigger reaction or compound. www.broad.mit.e...
Broad RNA_SPLICINGVIA_TRANSESTERIFICATION_REACTIONS View Gene Set 0.003132 27 0.02392 108 Genes annotated by the GO term GO:0000375. Splicing of RNA via a series of two transesterification reactions. www.broad.mit.e...
Broad REGULATION_OF_TRANSLATIONAL_INITIATION View Gene Set 0.003216 31 0.02434 109 Genes annotated by the GO term GO:0006446. Any process that modulates the frequency rate or extent of translational initiation. www.broad.mit.e...
Broad DNA_DAMAGE_CHECKPOINT View Gene Set 0.003291 20 0.02468 110 Genes annotated by the GO term GO:0000077. A signal transduction pathway induced by DNA damage that blocks cell cycle progression (in G1 G2 or metaphase) or slows the rate at which S phase proceeds. www.broad.mit.e...
Broad REGULATION_OF_CELL_GROWTH View Gene Set 0.003555 42 0.02642 111 Genes annotated by the GO term GO:0001558. Any process that modulates the frequency rate or extent of cell growth. www.broad.mit.e...
Broad NEGATIVE_REGULATION_OF_BINDING View Gene Set 0.003949 18 0.02909 112 Genes annotated by the GO term GO:0051100. Any process that stops or reduces the rate or extent of binding the selective interaction of a molecule with one or more specific sites on another molecule. www.broad.mit.e...
Broad PURINE_NUCLEOTIDE_METABOLIC_PROCESS View Gene Set 0.004288 11 0.03112 113 Genes annotated by the GO term GO:0006163. The chemical reactions and pathways involving a purine nucleotide a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_METABOLIC_PROCESS View Gene Set 0.004302 229 0.03112 113 Genes annotated by the GO term GO:0009893. Any process that activates or increases the frequency rate or extent of the chemical reactions and pathways within a cell or an organism. www.broad.mit.e...
Broad CELLULAR_MACROMOLECULE_METABOLIC_PROCESS View Gene Set 0.004339 1099 0.03112 113 Genes annotated by the GO term GO:0044260. The chemical reactions and pathways involving macromolecules large molecules including proteins nucleic acids and carbohydrates as carried out by individual cells. www.broad.mit.e...
Broad SPLICEOSOME_ASSEMBLY View Gene Set 0.00439 13 0.03122 116 Genes annotated by the GO term GO:0000245. The aggregation arrangement and bonding together of the spliceosome a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. www.broad.mit.e...
Broad MACROMOLECULE_LOCALIZATION View Gene Set 0.004444 228 0.03134 117 Genes annotated by the GO term GO:0033036. The processes by which a macromolecule is transported to or maintained in a specific location. www.broad.mit.e...
Broad ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION View Gene Set 0.004522 17 0.03161 118 Genes annotated by the GO term GO:0051656. The directed movement of an organelle to a specific location. www.broad.mit.e...
Broad ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CHROMATIN_ARCHITECTURE View Gene Set 0.004815 72 0.03294 119 Genes annotated by the GO term GO:0006325. The specification formation and maintenance of the physical structure of eukaryotic chromatin. www.broad.mit.e...
Broad INTERPHASE_OF_MITOTIC_CELL_CYCLE View Gene Set 0.004766 62 0.03294 119 Genes annotated by the GO term GO:0051329. Progression through interphase the stage of cell cycle between successive rounds of mitosis. Canonically interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs. www.broad.mit.e...
Broad CHROMOSOME_CONDENSATION View Gene Set 0.004831 10 0.03294 119 Genes annotated by the GO term GO:0030261. The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division or during apoptosis in eukaryotic cells. www.broad.mit.e...
Broad MRNA_SPLICE_SITE_SELECTION View Gene Set 0.004985 6 0.03371 122 Genes annotated by the GO term GO:0006376. Selection of a splice site by components of the assembling spliceosome. www.broad.mit.e...
Broad LYSOSOMAL_TRANSPORT View Gene Set 0.005378 11 0.03607 123 Genes annotated by the GO term GO:0007041. The directed movement of substances into out of or within a lysosome. www.broad.mit.e...
Broad MACROMOLECULE_CATABOLIC_PROCESS View Gene Set 0.005846 135 0.03858 124 Genes annotated by the GO term GO:0009057. The chemical reactions and pathways resulting in the breakdown of a macromolecule any large molecule including proteins nucleic acids and carbohydrates. www.broad.mit.e...
Broad G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE View Gene Set 0.005815 27 0.03858 124 Genes annotated by the GO term GO:0000082. Progression from G1 phase to S phase of the mitotic cell cycle. www.broad.mit.e...
Broad INTERPHASE View Gene Set 0.006304 68 0.04127 126 Genes annotated by the GO term GO:0051325. Progression through interphase the stage of cell cycle between successive rounds of chromosome segregation. Canonically interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs. www.broad.mit.e...
Broad REGULATION_OF_DEVELOPMENTAL_PROCESS View Gene Set 0.006627 432 0.04305 127 Genes annotated by the GO term GO:0050793. Any process that modulates the frequency rate or extent of development the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). www.broad.mit.e...
Broad VIRAL_REPRODUCTION View Gene Set 0.006783 41 0.04372 128 Genes annotated by the GO term GO:0016032. The process by which a virus reproduces. Usually this is by infection of a host cell replication of the viral genome and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently under particular circumstances 'complete' its life cycle. www.broad.mit.e...

Gene Set Collection: Broad.c5.CC

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad NUCLEUS View Gene Set 5.416e-48 1353 1.262e-45 1 Genes annotated by the GO term GO:0005634. A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells the nucleus contains all of the cell's chromosomes except the organellar chromosomes and is the site of RNA synthesis and processing. In some species or in specialized cell types RNA metabolism or DNA replication may be absent. www.broad.mit.e...
Broad ORGANELLE_PART View Gene Set 9.489e-23 1149 7.369e-21 2 Genes annotated by the GO term GO:0044422. Any constituent part of an organelle an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad INTRACELLULAR_ORGANELLE_PART View Gene Set 8.746e-23 1144 7.369e-21 2 Genes annotated by the GO term GO:0044446. A constituent part of an intracellular organelle an organized structure of distinctive morphology and function occurring within the cell. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad NUCLEAR_PART View Gene Set 9.388e-22 543 5.468e-20 4 Genes annotated by the GO term GO:0044428. Any constituent part of the nucleus a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. www.broad.mit.e...
Broad CYTOPLASM View Gene Set 1.443e-13 2054 6.722e-12 5 Genes annotated by the GO term GO:0005737. All of the contents of a cell excluding the plasma membrane and nucleus but including other subcellular structures. www.broad.mit.e...
Broad NUCLEAR_LUMEN View Gene Set 4.368e-13 365 1.696e-11 6 Genes annotated by the GO term GO:0031981. The volume enclosed by the nuclear inner membrane. www.broad.mit.e...
Broad ORGANELLE_LUMEN View Gene Set 3.46e-12 434 1.008e-10 7 Genes annotated by the GO term GO:0043233. The volume enclosed by the membranes of a particular organelle e.g. endoplasmic reticulum lumen or the space between the two lipid bilayers of a double membrane surrounding an organelle e.g. nuclear membrane lumen. www.broad.mit.e...
Broad MEMBRANE_ENCLOSED_LUMEN View Gene Set 3.46e-12 434 1.008e-10 7 Genes annotated by the GO term GO:0031974. The enclosed volume within a sealed membrane or between two sealed membranes. www.broad.mit.e...
Broad NUCLEOPLASM View Gene Set 5.384e-11 266 1.394e-09 9 Genes annotated by the GO term GO:0005654. That part of the nuclear content other than the chromosomes or the nucleolus. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX View Gene Set 3.045e-09 914 7.095e-08 10 Genes annotated by the GO term GO:0032991. A stable assembly of two or more macromolecules i.e. proteins nucleic acids carbohydrates or lipids in which the constituent parts function together. www.broad.mit.e...
Broad NON_MEMBRANE_BOUND_ORGANELLE View Gene Set 4.476e-08 613 8.692e-07 11 Genes annotated by the GO term GO:0043228. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane. Includes ribosomes the cytoskeleton and chromosomes. www.broad.mit.e...
Broad INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE View Gene Set 4.476e-08 613 8.692e-07 11 Genes annotated by the GO term GO:0043232. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes the cytoskeleton and chromosomes. www.broad.mit.e...
Broad CHROMOSOME View Gene Set 5.27e-08 122 9.446e-07 13 Genes annotated by the GO term GO:0005694. A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. www.broad.mit.e...
Broad NUCLEOPLASM_PART View Gene Set 6.75e-08 202 1.123e-06 14 Genes annotated by the GO term GO:0044451. Any constituent part of the nucleoplasm that part of the nuclear content other than the chromosomes or the nucleolus. www.broad.mit.e...
Broad MICROTUBULE_CYTOSKELETON View Gene Set 1.165e-07 146 1.81e-06 15 Genes annotated by the GO term GO:0015630. The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. www.broad.mit.e...
Broad CHROMOSOMAL_PART View Gene Set 3.582e-07 95 5.216e-06 16 Genes annotated by the GO term GO:0044427. Any constituent part of a chromosome a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. www.broad.mit.e...
Broad CYTOPLASMIC_PART View Gene Set 6.085e-07 1350 7.462e-06 17 Genes annotated by the GO term GO:0044444. Any constituent part of the cytoplasm all of the contents of a cell excluding the plasma membrane and nucleus but including other subcellular structures. www.broad.mit.e...
Broad SPINDLE View Gene Set 5.744e-07 37 7.462e-06 17 Genes annotated by the GO term GO:0005819. The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. www.broad.mit.e...
Broad NUCLEAR_ENVELOPE View Gene Set 5.796e-07 71 7.462e-06 17 Genes annotated by the GO term GO:0005635. The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space a gap of width 20-40 nm (also called the perinuclear space). www.broad.mit.e...
Broad PROTEIN_COMPLEX View Gene Set 1.175e-06 799 1.368e-05 20 Genes annotated by the GO term GO:0043234. Any protein group composed of two or more subunits which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE View Gene Set 5.886e-06 48 6.53e-05 21 Genes annotated by the GO term GO:0031965. Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX View Gene Set 1.085e-05 129 0.000115 22 Genes annotated by the GO term GO:0030529. A macromolecular complex containing both protein and RNA molecules. www.broad.mit.e...
Broad CHROMOSOMEPERICENTRIC_REGION View Gene Set 1.137e-05 31 0.0001152 23 Genes annotated by the GO term GO:0000775. The central region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes this region corresponds to a single area of the chromosome whereas in holocentric chromosomes it is evenly distributed along the chromosome. www.broad.mit.e...
Broad NUCLEOLUS View Gene Set 1.679e-05 116 0.000163 24 Genes annotated by the GO term GO:0005730. A small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA the processing of this RNA into 5.8S 18S and 28S components of ribosomal RNA and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. www.broad.mit.e...
Broad SPINDLE_MICROTUBULE View Gene Set 2.722e-05 15 0.0002537 25 Genes annotated by the GO term GO:0005876. Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. www.broad.mit.e...
Broad ENDOMEMBRANE_SYSTEM View Gene Set 3.639e-05 213 0.0003261 26 Genes annotated by the GO term GO:0012505. A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum Golgi bodies vesicles cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. www.broad.mit.e...
Broad DNA_DIRECTED_RNA_POLYMERASEII_HOLOENZYME View Gene Set 5.807e-05 65 0.0005011 27 Genes annotated by the GO term GO:0016591. Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA D E F and H which are required for promoter recognition and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA. www.broad.mit.e...
Broad KINETOCHORE View Gene Set 7.18e-05 25 0.0005975 28 Genes annotated by the GO term GO:0000776. A multisubunit complex that is located at the pericentric region of DNA and provides an attachment point for the spindle microtubules. www.broad.mit.e...
Broad MICROTUBULE View Gene Set 7.682e-05 31 0.0006172 29 Genes annotated by the GO term GO:0005874. Any of the long generally straight hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation e.g. in the spindle. www.broad.mit.e...
Broad NUCLEAR_PORE View Gene Set 9.897e-05 29 0.0007687 30 Genes annotated by the GO term GO:0005643. Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell where the inner and outer nuclear membranes are joined. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE_PART View Gene Set 0.0001088 40 0.0008176 31 Genes annotated by the GO term GO:0044453. Any constituent part of the nuclear membrane the envelope that surrounds the nucleus of eukaryotic cells. www.broad.mit.e...
Broad ORGANELLE_MEMBRANE View Gene Set 0.0001845 290 0.001343 32 Genes annotated by the GO term GO:0031090. The lipid bilayer surrounding an organelle. www.broad.mit.e...
Broad UBIQUITIN_LIGASE_COMPLEX View Gene Set 0.0003739 26 0.00264 33 Genes annotated by the GO term GO:0000151. A protein complex that includes a ubiquitin-protein ligase (E3) and other proteins that may confer substrate specificity on the complex. www.broad.mit.e...
Broad SPLICEOSOME View Gene Set 0.0004091 44 0.002803 34 Genes annotated by the GO term GO:0005681. A ribonucleoprotein complex containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron. www.broad.mit.e...
Broad PORE_COMPLEX View Gene Set 0.0006101 34 0.004061 35 Genes annotated by the GO term GO:0046930. Any small opening in a membrane that allows the passage of gases and/or liquids. www.broad.mit.e...
Broad ENVELOPE View Gene Set 0.001574 165 0.009909 36 Genes annotated by the GO term GO:0031975. A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers and may include a cell wall layer also includes the space between layers. www.broad.mit.e...
Broad ORGANELLE_ENVELOPE View Gene Set 0.001574 165 0.009909 36 Genes annotated by the GO term GO:0031967. A double membrane structure enclosing an organelle including two lipid bilayers and the region between them. In some cases an organelle envelope may have more than two membranes. www.broad.mit.e...
Broad GOLGI_APPARATUS_PART View Gene Set 0.001684 98 0.01033 38 Genes annotated by the GO term GO:0044431. Any constituent part of the Golgi apparatus a compound membranous cytoplasmic organelle of eukaryotic cells consisting of flattened ribosome-free vesicles arranged in a more or less regular stack. www.broad.mit.e...
Broad MICROTUBULE_ASSOCIATED_COMPLEX View Gene Set 0.002176 47 0.01237 39 Genes annotated by the GO term GO:0005875. Any multimeric complex connected to a microtubule. www.broad.mit.e...
Broad MEDIATOR_COMPLEX View Gene Set 0.002118 18 0.01237 39 Genes annotated by the GO term GO:0000119. A protein complex that enables the RNA polymerase II-general RNA polymerase II transcription factor complex to react to transcriptional activator proteins; also enhances the level of basal transcription. www.broad.mit.e...
Broad INTEGRATOR_COMPLEX View Gene Set 0.002148 13 0.01237 39 Genes annotated by the GO term GO:0032039. A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II. www.broad.mit.e...
Broad PEROXISOMAL_MEMBRANE View Gene Set 0.00277 12 0.01393 42 Genes annotated by the GO term GO:0005778. The lipid bilayer surrounding a peroxisome. www.broad.mit.e...
Broad NUCLEAR_CHROMOSOME View Gene Set 0.002757 53 0.01393 42 Genes annotated by the GO term GO:0000228. A chromosome found in the nucleus of a eukaryotic cell. www.broad.mit.e...
Broad MICROBODY_MEMBRANE View Gene Set 0.00277 12 0.01393 42 Genes annotated by the GO term GO:0031903. The lipid bilayer surrounding a microbody. www.broad.mit.e...
Broad TRANSPORT_VESICLE View Gene Set 0.00273 29 0.01393 42 Genes annotated by the GO term GO:0030133. Any of the vesicles of the constitutive secretory pathway which carry cargo from the endoplasmic reticulum to the Golgi between Golgi cisternae and to destinations within or outside the cell. www.broad.mit.e...
Broad CENTROSOME View Gene Set 0.002571 55 0.01393 42 Genes annotated by the GO term GO:0005813. A structure comprised of a core structure (in most organisms a pair of centrioles) and peripheral material from which a microtubule-based structure such as a spindle apparatus is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells though in animal cells it changes continually during the cell-division cycle. www.broad.mit.e...
Broad TRANSCRIPTION_FACTOR_COMPLEX View Gene Set 0.00281 84 0.01393 42 Genes annotated by the GO term GO:0005667. Any complex distinct from RNA polymerase including one or more polypeptides capable of binding DNA at promoters or at cis-acting regulatory sequences and regulating transcription. www.broad.mit.e...
Broad NUCLEOLAR_PART View Gene Set 0.003006 16 0.01459 48 Genes annotated by the GO term GO:0044452. Any constituent part of a nucleolus a small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. www.broad.mit.e...
Broad GOLGI_APPARATUS View Gene Set 0.003532 222 0.0168 49 Genes annotated by the GO term GO:0005794. A compound membranous cytoplasmic organelle of eukaryotic cells consisting of flattened ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle while in invertebrates and plants where they are known usually as dictyosomes there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis in the vicinity of the cis face trans in the vicinity of the trans face and medial lying between the cis and trans regions. www.broad.mit.e...
Broad MITOCHONDRION View Gene Set 0.004008 335 0.01831 50 Genes annotated by the GO term GO:0005739. A semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. www.broad.mit.e...
Broad TRANS_GOLGI_NETWORK View Gene Set 0.003951 21 0.01831 50 Genes annotated by the GO term GO:0005802. The network of interconnected tubular and cisternal structures located at the side of the Golgi apparatus distal to the endoplasmic reticulum from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. www.broad.mit.e...
Broad CYTOSKELETAL_PART View Gene Set 0.004877 231 0.02185 52 Genes annotated by the GO term GO:0044430. Any constituent part of the cytoskeleton a cellular scaffolding or skeleton that maintains cell shape enables some cell motion (using structures such as flagella and cilia) and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments microfilaments microtubules and the microtrabecular lattice. www.broad.mit.e...
Broad LATE_ENDOSOME View Gene Set 0.005987 12 0.02593 53 Genes annotated by the GO term GO:0005770. A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear being concentrated near the microtubule organizing center. www.broad.mit.e...
Broad PEROXISOMAL_PART View Gene Set 0.00618 13 0.02593 53 Genes annotated by the GO term GO:0044439. Any constituent part of a peroxisome a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2). www.broad.mit.e...
Broad MICROBODY_PART View Gene Set 0.00618 13 0.02593 53 Genes annotated by the GO term GO:0044438. Any constituent part of a microbody a cytoplasmic organelle spherical or oval in shape that is bounded by a single membrane and contains oxidative enzymes especially those utilizing hydrogen peroxide (H2O2). www.broad.mit.e...
Broad CONDENSED_CHROMOSOME View Gene Set 0.006231 32 0.02593 53 Genes annotated by the GO term GO:0000793. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. www.broad.mit.e...
Broad CHROMATIN View Gene Set 0.007025 35 0.02872 57 Genes annotated by the GO term GO:0000785. The ordered and organized complex of DNA and protein that forms the chromosome. www.broad.mit.e...
Broad MICROBODY View Gene Set 0.008233 46 0.03251 58 Genes annotated by the GO term GO:0042579. Cytoplasmic organelles spherical or oval in shape that are bounded by a single membrane and contain oxidative enzymes especially those utilizing hydrogen peroxide (H2O2). www.broad.mit.e...
Broad PEROXISOME View Gene Set 0.008233 46 0.03251 58 Genes annotated by the GO term GO:0005777. A small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2). www.broad.mit.e...
Broad KINESIN_COMPLEX View Gene Set 0.008795 14 0.03359 60 Genes annotated by the GO term GO:0005871. Any complex that includes a dimer of molecules from the kinesin superfamily a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity or motor which converts the free energy of the gamma phosphate bond of ATP into mechanical work. www.broad.mit.e...
Broad MICROTUBULE_ORGANIZING_CENTER View Gene Set 0.008676 64 0.03359 60 Genes annotated by the GO term GO:0005815. A region in a eukaryotic cell such as a centrosome or basal body from which microtubules grow. www.broad.mit.e...
Broad NUCLEAR_CHROMOSOME_PART View Gene Set 0.01122 33 0.04217 62 Genes annotated by the GO term GO:0044454. Any constituent part of a nuclear chromosome a chromosome found in the nucleus of a eukaryotic cell. www.broad.mit.e...
Broad NUCLEAR_CHROMATIN View Gene Set 0.01238 14 0.04577 63 Genes annotated by the GO term GO:0000790. The ordered and organized complex of DNA and protein that forms the chromosome in the nucleus. www.broad.mit.e...
Broad CYTOSKELETON View Gene Set 0.0127 359 0.04625 64 Genes annotated by the GO term GO:0005856. Any of the various filamentous elements that form the internal framework of cells and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments microfilaments microtubules the microtrabecular lattice and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions including cellular movement cell division endocytosis and movement of organelles. www.broad.mit.e...
Broad SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX View Gene Set 0.01374 20 0.04925 65 Genes annotated by the GO term GO:0030532. A complex composed of RNA of the small nuclear RNA (snRNA) class and protein found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain e.g. U1 snRNP or U4/U6 snRNP. Many but not all of these complexes are involved in splicing of nuclear mRNAs. www.broad.mit.e...

Gene Set Collection: Broad.c5.MF

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad TRANSCRIPTION_FACTOR_BINDING View Gene Set 5.493e-14 300 2.175e-11 1 Genes annotated by the GO term GO:0008134. Interacting selectively with a transcription factor any protein required to initiate or regulate transcription. www.broad.mit.e...
Broad TRANSCRIPTION_COFACTOR_ACTIVITY View Gene Set 2.657e-11 222 5.261e-09 2 Genes annotated by the GO term GO:0003712. The function that links a sequence-specific transcription factor to the core RNA polymerase II complex but does not bind DNA itself. www.broad.mit.e...
Broad TRANSCRIPTION_ACTIVATOR_ACTIVITY View Gene Set 1.327e-09 169 1.751e-07 3 Genes annotated by the GO term GO:0016563. Any transcription regulator activity required for initiation or upregulation of transcription. www.broad.mit.e...
Broad TRANSCRIPTION_COACTIVATOR_ACTIVITY View Gene Set 4.185e-08 121 4.143e-06 4 Genes annotated by the GO term GO:0003713. The function of a transcription cofactor that activates transcription from a RNA polymerase II promoter; does not bind DNA itself. www.broad.mit.e...
Broad TRANSCRIPTION_REPRESSOR_ACTIVITY View Gene Set 1.115e-06 146 8.185e-05 5 Genes annotated by the GO term GO:0016564. Any transcription regulator activity that prevents or downregulates transcription. www.broad.mit.e...
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS View Gene Set 1.24e-06 414 8.185e-05 5 Genes annotated by the GO term GO:0016772. Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). www.broad.mit.e...
Broad PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY View Gene Set 1.235e-05 200 0.0005931 7 Genes annotated by the GO term GO:0004674. Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate. www.broad.mit.e...
Broad NUCLEAR_HORMONE_RECEPTOR_BINDING View Gene Set 1.326e-05 28 0.0005931 7 Genes annotated by the GO term GO:0035257. Interacting selectively with a nuclear hormone receptor a ligand-dependent receptor found in the nucleus of the cell. www.broad.mit.e...
Broad HORMONE_RECEPTOR_BINDING View Gene Set 1.348e-05 29 0.0005931 7 Genes annotated by the GO term GO:0051427. Interacting selectively with a receptor for hormones. www.broad.mit.e...
Broad PROTEIN_KINASE_ACTIVITY View Gene Set 1.836e-05 278 0.0007271 10 Genes annotated by the GO term GO:0004672. Catalysis of the phosphorylation of an amino acid residue in a protein usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. www.broad.mit.e...
Broad PHOSPHOTRANSFERASE_ACTIVITY_ALCOHOL_GROUP_AS_ACCEPTOR View Gene Set 3.783e-05 326 0.001362 11 Genes annotated by the GO term GO:0016773. Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). www.broad.mit.e...
Broad KINASE_ACTIVITY View Gene Set 4.538e-05 359 0.001441 12 Genes annotated by the GO term GO:0016301. Catalysis of the transfer of a phosphate group usually from ATP to a substrate molecule. www.broad.mit.e...
Broad TUBULIN_BINDING View Gene Set 4.732e-05 46 0.001441 12 Genes annotated by the GO term GO:0015631. Interacting selectively with monomeric or multimeric forms of tubulin including microtubules. www.broad.mit.e...
Broad THYROID_HORMONE_RECEPTOR_BINDING View Gene Set 5.941e-05 17 0.001681 14 Genes annotated by the GO term GO:0046966. Interacting selectively with a thyroid hormone receptor. www.broad.mit.e...
Broad CHROMATIN_BINDING View Gene Set 9.866e-05 32 0.002442 15 Genes annotated by the GO term GO:0003682. Interacting selectively with chromatin the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. www.broad.mit.e...
Broad DNA_BINDING View Gene Set 9.392e-05 587 0.002442 15 Genes annotated by the GO term GO:0003677. Interacting selectively with DNA (deoxyribonucleic acid). www.broad.mit.e...
Broad NUCLEOTIDE_BINDING View Gene Set 0.0001787 218 0.004163 17 Genes annotated by the GO term GO:0000166. Interacting selectively with a nucleotide any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose moiety. www.broad.mit.e...
Broad LIGASE_ACTIVITY_FORMING_CARBON_NITROGEN_BONDS View Gene Set 0.0002488 68 0.005473 18 Genes annotated by the GO term GO:0016879. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. www.broad.mit.e...
Broad RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY View Gene Set 0.0002636 182 0.005494 19 Genes annotated by the GO term GO:0003702. Functions to initiate or regulate RNA polymerase II transcription. www.broad.mit.e...
Broad SMALL_CONJUGATING_PROTEIN_LIGASE_ACTIVITY View Gene Set 0.0002784 51 0.005513 20 Genes annotated by the GO term GO:0019787. Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of a small conjugating protein such as ubiquitin or a ubiquitin-like protein and a substrate lysine residue. www.broad.mit.e...
Broad ACID_AMINO_ACID_LIGASE_ACTIVITY View Gene Set 0.0003696 57 0.00695 21 Genes annotated by the GO term GO:0016881. Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. www.broad.mit.e...
Broad SMALL_PROTEIN_CONJUGATING_ENZYME_ACTIVITY View Gene Set 0.0003861 52 0.00695 21 Genes annotated by the GO term GO:0008639. Catalysis of the covalent attachment of small proteins such as ubiquitin or ubiquitin-like proteins to lysine residues on a target protein. This function may be performed alone or in conjunction with an E3 ubiquitin-like protein ligase. www.broad.mit.e...
Broad MICROTUBULE_BINDING View Gene Set 0.0004488 32 0.007728 23 Genes annotated by the GO term GO:0008017. Interacting selectively with microtubules filaments composed of tubulin monomers. www.broad.mit.e...
Broad TRANSCRIPTION_COREPRESSOR_ACTIVITY View Gene Set 0.0004878 91 0.008049 24 Genes annotated by the GO term GO:0003714. The function of a transcription cofactor that represses transcription from a RNA polymerase II promoter; does not bind DNA itself. www.broad.mit.e...
Broad TRANSLATION_REGULATOR_ACTIVITY View Gene Set 0.0008633 41 0.01315 25 Genes annotated by the GO term GO:0045182. Any substance involved in the initiation activation perpetuation repression or termination of polypeptide synthesis at the ribosome. www.broad.mit.e...
Broad PURINE_RIBONUCLEOTIDE_BINDING View Gene Set 0.0008611 200 0.01315 25 Genes annotated by the GO term GO:0032555. Interacting selectively with a purine ribonucleotide any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. www.broad.mit.e...
Broad GENERAL_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY View Gene Set 0.0009042 32 0.01326 27 Genes annotated by the GO term GO:0016251. Any function that supports basal (unregulated) transcription of genes by core RNA polymerase II. Five general transcription factors are necessary and sufficient for such basal transcription in yeast: TFIIB TFIID TFIIE TFIIF TFIIH and TATA-binding protein (TBF). www.broad.mit.e...
Broad UBIQUITIN_PROTEIN_LIGASE_ACTIVITY View Gene Set 0.001012 49 0.01402 28 Genes annotated by the GO term GO:0004842. Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. www.broad.mit.e...
Broad ENDONUCLEASE_ACTIVITY_GO_0016893 View Gene Set 0.001027 11 0.01402 28 Genes annotated by the GO term GO:0016893. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. www.broad.mit.e...
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_GROUPS_OTHER_THAN_AMINO_ACYL_GROUPS View Gene Set 0.001065 47 0.01405 30 Genes annotated by the GO term GO:0016747. Catalysis of the transfer of an acyl group other than amino-acyl from one compound (donor) to another (acceptor). www.broad.mit.e...
Broad TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING View Gene Set 0.001172 39 0.01497 31 Genes annotated by the GO term GO:0008135. Functions during translation by binding nucleic acids during polypeptide synthesis at the ribosome. www.broad.mit.e...
Broad LIGASE_ACTIVITY View Gene Set 0.001226 97 0.01518 32 Genes annotated by the GO term GO:0016874. Catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. www.broad.mit.e...
Broad PURINE_NUCLEOTIDE_BINDING View Gene Set 0.001339 205 0.01559 33 Genes annotated by the GO term GO:0017076. Interacting selectively with purine nucleotides any compound consisting of a purine nucleoside esterified with (ortho)phosphate. www.broad.mit.e...
Broad DOUBLE_STRANDED_DNA_BINDING View Gene Set 0.001303 32 0.01559 33 Genes annotated by the GO term GO:0003690. Interacting selectively with double-stranded DNA. www.broad.mit.e...
Broad RNA_SPLICING_FACTOR_ACTIVITYTRANSESTERIFICATION_MECHANISM View Gene Set 0.001408 14 0.01593 35 Genes annotated by the GO term GO:0031202. An activity which binds RNA and functions to assist splicing of substrate RNA(s) by facilitating the formation and stabilization of a catalytic conformation in which the splice junctions of the RNA(s) to be spliced are positioned for a transesterification reaction that occurs between two sites within the RNA(s) to be spliced. www.broad.mit.e...
Broad GTP_BINDING View Gene Set 0.002397 46 0.02341 36 Genes annotated by the GO term GO:0005525. Interacting selectively with GTP guanosine triphosphate. www.broad.mit.e...
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS View Gene Set 0.002332 56 0.02341 36 Genes annotated by the GO term GO:0016746. Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). www.broad.mit.e...
Broad N_ACETYLTRANSFERASE_ACTIVITY View Gene Set 0.002424 21 0.02341 36 Genes annotated by the GO term GO:0008080. Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. www.broad.mit.e...
Broad GUANYL_NUCLEOTIDE_BINDING View Gene Set 0.002397 47 0.02341 36 Genes annotated by the GO term GO:0019001. Interacting selectively with guanyl nucleotides any compound consisting of guanosine esterified with (ortho)phosphate. www.broad.mit.e...
Broad STRUCTURE_SPECIFIC_DNA_BINDING View Gene Set 0.002392 55 0.02341 36 Genes annotated by the GO term GO:0043566. Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. www.broad.mit.e...
Broad ENZYME_BINDING View Gene Set 0.002371 175 0.02341 36 Genes annotated by the GO term GO:0019899. Interacting selectively with any enzyme. www.broad.mit.e...
Broad ACETYLTRANSFERASE_ACTIVITY View Gene Set 0.002672 23 0.02519 42 Genes annotated by the GO term GO:0016407. Catalysis of the transfer of an acetyl group to an acceptor molecule. www.broad.mit.e...
Broad BETA_TUBULIN_BINDING View Gene Set 0.00275 10 0.0252 43 Genes annotated by the GO term GO:0048487. Interacting selectively with the microtubule constituent protein beta-tubulin. www.broad.mit.e...
Broad STEROID_HORMONE_RECEPTOR_BINDING View Gene Set 0.0028 10 0.0252 43 Genes annotated by the GO term GO:0035258. Interacting selectively with a steroid hormone receptor. www.broad.mit.e...
Broad NUCLEOTIDYLTRANSFERASE_ACTIVITY View Gene Set 0.0031 47 0.02728 45 Genes annotated by the GO term GO:0016779. Catalysis of the transfer of a nucleotidyl group to a reactant. www.broad.mit.e...
Broad HISTONE_ACETYLTRANSFERASE_ACTIVITY View Gene Set 0.004006 16 0.03449 46 Genes annotated by the GO term GO:0004402. Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone. www.broad.mit.e...
Broad RNA_BINDING View Gene Set 0.004704 236 0.03964 47 Genes annotated by the GO term GO:0003723. Interacting selectively with an RNA molecule or a portion thereof. www.broad.mit.e...
Broad N_ACYLTRANSFERASE_ACTIVITY View Gene Set 0.004805 24 0.03964 48 Genes annotated by the GO term GO:0016410. Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule. www.broad.mit.e...
Broad SMALL_CONJUGATING_PROTEIN_BINDING View Gene Set 0.005129 12 0.04145 49 Genes annotated by the GO term GO:0032182. Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein. www.broad.mit.e...
Broad TRANSLATION_INITIATION_FACTOR_ACTIVITY View Gene Set 0.005774 24 0.04573 50 Genes annotated by the GO term GO:0003743. Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. www.broad.mit.e...
Broad RNA_HELICASE_ACTIVITY View Gene Set 0.006432 24 0.04898 51 Genes annotated by the GO term GO:0003724. Catalysis of the unwinding of an RNA helix. www.broad.mit.e...
Broad ENDORIBONUCLEASE_ACTIVITY View Gene Set 0.006368 13 0.04898 51 Genes annotated by the GO term GO:0004521. Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. www.broad.mit.e...

Gene Set Collection: PMID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
PMID 15302935 View Gene Set 5.074e-42 773 1.272e-38 1 Large-scale characterization of HeLa cell nuclear phosphoproteins. www.ncbi.nlm.ni...
PMID 16964243 View Gene Set 1.325e-31 504 1.661e-28 2 A probability-based approach for high-throughput protein phosphorylation analysis and site localization. www.ncbi.nlm.ni...
PMID 16565220 View Gene Set 1.956e-14 210 1.635e-11 3 Phosphoproteome analysis of the human mitotic spindle. www.ncbi.nlm.ni...
PMID 15324660 View Gene Set 1.539e-13 242 9.647e-11 4 Proteomic functional and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. www.ncbi.nlm.ni...
PMID 15231748 View Gene Set 3.543e-13 519 1.777e-10 5 Functional proteomics mapping of a human signaling pathway. www.ncbi.nlm.ni...
PMID 17643375 View Gene Set 3.137e-12 391 1.311e-09 6 Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. www.ncbi.nlm.ni...
PMID 8619474 View Gene Set 3.366e-10 534 1.206e-07 7 A "double adaptor" method for improved shotgun library construction. www.ncbi.nlm.ni...
PMID 12429849 View Gene Set 2.087e-09 106 6.541e-07 8 Functional proteomic analysis of human nucleolus. www.ncbi.nlm.ni...
PMID 12226669 View Gene Set 2.699e-09 108 7.293e-07 9 Comprehensive proteomic analysis of the human spliceosome. www.ncbi.nlm.ni...
PMID 9110174 View Gene Set 2.909e-09 528 7.293e-07 9 Large-scale concatenation cDNA sequencing. www.ncbi.nlm.ni...
PMID 11230166 View Gene Set 2.196e-08 748 5.004e-06 11 Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. www.ncbi.nlm.ni...
PMID 11256614 View Gene Set 5.716e-08 522 1.194e-05 12 Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. www.ncbi.nlm.ni...
PMID 15635413 View Gene Set 9.019e-08 421 1.739e-05 13 Nucleolar proteome dynamics. www.ncbi.nlm.ni...
PMID 20508983 View Gene Set 1.37e-07 102 2.453e-05 14 Centrosome-related genes genetic variation and risk of breast cancer. www.ncbi.nlm.ni...
PMID 9039502 View Gene Set 2.914e-07 84 4.871e-05 15 Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. www.ncbi.nlm.ni...
PMID 11991638 View Gene Set 3.902e-07 74 6.113e-05 16 Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. www.ncbi.nlm.ni...
PMID 16083285 View Gene Set 4.373e-07 59 6.448e-05 17 Global phosphoproteome of HT-29 human colon adenocarcinoma cells. www.ncbi.nlm.ni...
PMID 15592455 View Gene Set 6.703e-07 317 9.336e-05 18 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. www.ncbi.nlm.ni...
PMID 16713569 View Gene Set 1.358e-06 570 0.0001792 19 A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. www.ncbi.nlm.ni...
PMID 12168954 View Gene Set 2.2e-06 225 0.0002758 20 Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. www.ncbi.nlm.ni...
PMID 20085707 View Gene Set 3.284e-06 42 0.000392 21 Aire's partners in the molecular control of immunological tolerance. www.ncbi.nlm.ni...
PMID 11076961 View Gene Set 4.079e-06 14 0.0004648 22 Characterization of vertebrate cohesin complexes and their regulation in prophase. www.ncbi.nlm.ni...
PMID 16387653 View Gene Set 4.481e-06 42 0.0004884 23 ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. www.ncbi.nlm.ni...
PMID 15489336 View Gene Set 5.057e-06 722 0.0005147 24 From ORFeome to biology: a functional genomics pipeline. www.ncbi.nlm.ni...
PMID 16381901 View Gene Set 5.133e-06 720 0.0005147 24 The LIFEdb database in 2006. www.ncbi.nlm.ni...
PMID 10810093 View Gene Set 5.651e-06 151 0.0005211 26 Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. www.ncbi.nlm.ni...
PMID 15232106 View Gene Set 5.819e-06 30 0.0005211 26 Self-assembling protein microarrays. www.ncbi.nlm.ni...
PMID 8724849 View Gene Set 5.776e-06 41 0.0005211 26 Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. www.ncbi.nlm.ni...
PMID 7584044 View Gene Set 8.496e-06 41 0.0007344 29 Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. www.ncbi.nlm.ni...
PMID 19738611 View Gene Set 1.565e-05 39 0.001308 30 Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis. www.ncbi.nlm.ni...
PMID 15778465 View Gene Set 1.646e-05 91 0.001331 31 Targeted proteomic analysis of 14-3-3 sigma a p53 effector commonly silenced in cancer. www.ncbi.nlm.ni...
PMID 12706105 View Gene Set 1.788e-05 182 0.00136 32 Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. www.ncbi.nlm.ni...
PMID 12837248 View Gene Set 1.816e-05 22 0.00136 32 The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. www.ncbi.nlm.ni...
PMID 19060904 View Gene Set 1.845e-05 130 0.00136 32 An empirical framework for binary interactome mapping. www.ncbi.nlm.ni...
PMID 15146197 View Gene Set 2.199e-05 693 0.001575 35 Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. www.ncbi.nlm.ni...
PMID 9267036 View Gene Set 2.494e-05 15 0.001736 36 Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. www.ncbi.nlm.ni...
PMID 14559993 View Gene Set 2.843e-05 51 0.001902 37 Regulation of alternative splicing by SRrp86 and its interacting proteins. www.ncbi.nlm.ni...
PMID 19183483 View Gene Set 2.89e-05 17 0.001902 37 Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort. www.ncbi.nlm.ni...
PMID 8590280 View Gene Set 2.96e-05 41 0.001902 37 Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. www.ncbi.nlm.ni...
PMID 11042152 View Gene Set 3.806e-05 315 0.002385 40 Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. www.ncbi.nlm.ni...
PMID 18228528 View Gene Set 3.942e-05 13 0.00241 41 Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm. www.ncbi.nlm.ni...
PMID 12791985 View Gene Set 4.107e-05 37 0.002452 42 Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. www.ncbi.nlm.ni...
PMID 18162579 View Gene Set 4.224e-05 22 0.002463 43 Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. www.ncbi.nlm.ni...
PMID 11279123 View Gene Set 7.362e-05 31 0.004194 44 The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 12228227 View Gene Set 9.017e-05 30 0.004914 45 Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1. www.ncbi.nlm.ni...
PMID 9455484 View Gene Set 8.833e-05 56 0.004914 45 Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. www.ncbi.nlm.ni...
PMID 20516191 View Gene Set 9.263e-05 12 0.004941 47 A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins). www.ncbi.nlm.ni...
PMID 9472028 View Gene Set 9.721e-05 12 0.005077 48 SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. www.ncbi.nlm.ni...
PMID 18485873 View Gene Set 0.0001103 13 0.005646 49 Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. www.ncbi.nlm.ni...
PMID 15345747 View Gene Set 0.000116 148 0.005704 50 Phosphoproteomic analysis of the developing mouse brain. www.ncbi.nlm.ni...
PMID 15504738 View Gene Set 0.000114 19 0.005704 50 Genes affecting the cell cycle growth maintenance and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. www.ncbi.nlm.ni...
PMID 15144186 View Gene Set 0.0001218 133 0.005871 52 Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. www.ncbi.nlm.ni...
PMID 9731529 View Gene Set 0.0001449 24 0.006854 53 Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. www.ncbi.nlm.ni...
PMID 10793135 View Gene Set 0.0001685 18 0.007821 54 Mitotic regulation of the APC activator proteins CDC20 and CDH1. www.ncbi.nlm.ni...
PMID 11535616 View Gene Set 0.0002014 18 0.008923 55 Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1 BUB3 CDC20 and MAD2. www.ncbi.nlm.ni...
PMID 12221128 View Gene Set 0.0002029 70 0.008923 55 Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex. www.ncbi.nlm.ni...
PMID 14593737 View Gene Set 0.0002014 18 0.008923 55 The mitotic checkpoint: a signaling pathway that allows a single unattached kinetochore to inhibit mitotic exit. www.ncbi.nlm.ni...
PMID 10230407 View Gene Set 0.0002092 12 0.009042 58 ROC1 a homolog of APC11 represents a family of cullin partners with an associated ubiquitin ligase activity. www.ncbi.nlm.ni...
PMID 9710619 View Gene Set 0.0002579 16 0.01096 59 A human RNA polymerase II complex containing factors that modify chromatin structure. www.ncbi.nlm.ni...
PMID 10231032 View Gene Set 0.0002783 103 0.01161 60 Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. www.ncbi.nlm.ni...
PMID 15989967 View Gene Set 0.0002872 34 0.01161 60 MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. www.ncbi.nlm.ni...
PMID 17148452 View Gene Set 0.0002836 87 0.01161 60 Characterization of the interactome of the human MutL homologues MLH1 PMS1 and PMS2. www.ncbi.nlm.ni...
PMID 14667819 View Gene Set 0.0003444 112 0.01371 63 Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. www.ncbi.nlm.ni...
PMID 16364912 View Gene Set 0.0003518 12 0.01378 64 Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. www.ncbi.nlm.ni...
PMID 11931757 View Gene Set 0.0003594 22 0.01386 65 Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. www.ncbi.nlm.ni...
PMID 12070128 View Gene Set 0.0003897 17 0.0148 66 Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1. www.ncbi.nlm.ni...
PMID 11742988 View Gene Set 0.0004242 20 0.01587 67 APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box. www.ncbi.nlm.ni...
PMID 11543634 View Gene Set 0.0004473 58 0.01617 68 The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. www.ncbi.nlm.ni...
PMID 12838346 View Gene Set 0.0004514 68 0.01617 68 Human and mouse proteases: a comparative genomic approach. www.ncbi.nlm.ni...
PMID 19710015 View Gene Set 0.0004478 48 0.01617 68 The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor. www.ncbi.nlm.ni...
PMID 14638676 View Gene Set 0.0004994 28 0.01763 71 A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2. www.ncbi.nlm.ni...
PMID 17577209 View Gene Set 0.0005202 28 0.01811 72 The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing. www.ncbi.nlm.ni...
PMID 12963728 View Gene Set 0.000532 21 0.01827 73 Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. www.ncbi.nlm.ni...
PMID 11790298 View Gene Set 0.0005642 208 0.01873 74 Directed proteomic analysis of the human nucleolus. www.ncbi.nlm.ni...
PMID 12388589 View Gene Set 0.000559 17 0.01873 74 A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. www.ncbi.nlm.ni...
PMID 9734811 View Gene Set 0.0005677 102 0.01873 74 Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. www.ncbi.nlm.ni...
PMID 17363900 View Gene Set 0.0006051 14 0.0197 77 The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. www.ncbi.nlm.ni...
PMID 15725353 View Gene Set 0.0006501 21 0.0209 78 The Vpr protein from HIV-1: distinct roles along the viral life cycle. www.ncbi.nlm.ni...
PMID 11113176 View Gene Set 0.0006648 11 0.02106 79 Studies of nematode TFIIE function reveal a link between Ser-5 phosphorylation of RNA polymerase II and the transition from transcription initiation to elongation. www.ncbi.nlm.ni...
PMID 11832478 View Gene Set 0.0006721 12 0.02106 79 Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria. www.ncbi.nlm.ni...
PMID 11331580 View Gene Set 0.000684 39 0.02117 81 The tripartite motif family identifies cell compartments. www.ncbi.nlm.ni...
PMID 9628581 View Gene Set 0.0007102 105 0.02171 82 Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. www.ncbi.nlm.ni...
PMID 16341674 View Gene Set 0.0007272 392 0.02196 83 Transcriptome analysis of human gastric cancer. www.ncbi.nlm.ni...
PMID 20056645 View Gene Set 0.0007425 32 0.022 84 Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome. www.ncbi.nlm.ni...
PMID 20174623 View Gene Set 0.000746 18 0.022 84 Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance. www.ncbi.nlm.ni...
PMID 12609982 View Gene Set 0.0007636 11 0.02226 86 TIP120A associates with cullins and modulates ubiquitin ligase activity. www.ncbi.nlm.ni...
PMID 10942595 View Gene Set 0.0008295 25 0.0239 87 A visual intracellular classification strategy for uncharacterized human proteins. www.ncbi.nlm.ni...
PMID 10318877 View Gene Set 0.0008402 10 0.02394 88 Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex. www.ncbi.nlm.ni...
PMID 10548110 View Gene Set 0.0008946 16 0.02486 89 Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex. www.ncbi.nlm.ni...
PMID 11078522 View Gene Set 0.0009197 12 0.02486 89 The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. www.ncbi.nlm.ni...
PMID 11340163 View Gene Set 0.0008946 16 0.02486 89 A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression. www.ncbi.nlm.ni...
PMID 12614612 View Gene Set 0.0009319 19 0.02486 89 Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. www.ncbi.nlm.ni...
PMID 15226314 View Gene Set 0.0009376 20 0.02486 89 Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. www.ncbi.nlm.ni...
PMID 17525332 View Gene Set 0.0009422 22 0.02486 89 ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. www.ncbi.nlm.ni...
PMID 19165527 View Gene Set 0.0009105 84 0.02486 89 Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. www.ncbi.nlm.ni...
PMID 11500380 View Gene Set 0.0009961 10 0.02601 96 A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. www.ncbi.nlm.ni...
PMID 11867769 View Gene Set 0.001033 22 0.02643 97 The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro. www.ncbi.nlm.ni...
PMID 16051665 View Gene Set 0.001023 15 0.02643 97 Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes. www.ncbi.nlm.ni...
PMID 11095689 View Gene Set 0.001107 17 0.02804 99 The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase. www.ncbi.nlm.ni...
PMID 15707391 View Gene Set 0.001173 23 0.02941 100 DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. www.ncbi.nlm.ni...
PMID 15050687 View Gene Set 0.001188 11 0.02948 101 Proliferation inhibition of astrocytes neurons and non-glial cells by intracellularly expressed human immunodeficiency virus type 1 (HIV-1) Tat protein. www.ncbi.nlm.ni...
PMID 18950845 View Gene Set 0.001257 88 0.03089 102 Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. www.ncbi.nlm.ni...
PMID 15333839 View Gene Set 0.001281 12 0.03118 103 E protein silencing by the leukemogenic AML1-ETO fusion protein. www.ncbi.nlm.ni...
PMID 15572661 View Gene Set 0.001335 22 0.03219 104 Negative modulation of androgen receptor transcriptional activity by Daxx. www.ncbi.nlm.ni...
PMID 18997788 View Gene Set 0.001364 10 0.03257 105 The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction. www.ncbi.nlm.ni...
PMID 17274640 View Gene Set 0.001386 30 0.03277 106 A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis. www.ncbi.nlm.ni...
PMID 12852856 View Gene Set 0.001441 61 0.03285 107 Polo-like kinase 1 regulates Nlp a centrosome protein involved in microtubule nucleation. www.ncbi.nlm.ni...
PMID 15808510 View Gene Set 0.001423 10 0.03285 107 Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation. www.ncbi.nlm.ni...
PMID 16462731 View Gene Set 0.001441 62 0.03285 107 The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation. www.ncbi.nlm.ni...
PMID 7790358 View Gene Set 0.001441 61 0.03285 107 Cell cycle regulation of the activity and subcellular localization of Plk1 a human protein kinase implicated in mitotic spindle function. www.ncbi.nlm.ni...
PMID 10048485 View Gene Set 0.001518 101 0.03351 111 Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. www.ncbi.nlm.ni...
PMID 10470851 View Gene Set 0.001495 103 0.03351 111 Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. www.ncbi.nlm.ni...
PMID 10601273 View Gene Set 0.001516 21 0.03351 111 Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein whereas export is due to a nuclear export signal sequence in glucokinase. www.ncbi.nlm.ni...
PMID 10866662 View Gene Set 0.001537 10 0.03351 111 A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein. www.ncbi.nlm.ni...
PMID 15175163 View Gene Set 0.001531 47 0.03351 111 A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. www.ncbi.nlm.ni...
PMID 11076968 View Gene Set 0.001552 62 0.03355 116 The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion. www.ncbi.nlm.ni...
PMID 16239144 View Gene Set 0.00159 16 0.03407 117 Integrator a multiprotein mediator of small nuclear RNA processing associates with the C-terminal repeat of RNA polymerase II. www.ncbi.nlm.ni...
PMID 9305922 View Gene Set 0.001644 12 0.03494 118 Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase II holoenzyme capable of promoter-specific initiation and responsive to transcriptional activators. www.ncbi.nlm.ni...
PMID 10704444 View Gene Set 0.001776 16 0.03741 119 PEX19 binds multiple peroxisomal membrane proteins is predominantly cytoplasmic and is required for peroxisome membrane synthesis. www.ncbi.nlm.ni...
PMID 11013263 View Gene Set 0.001808 16 0.03777 120 A novel nuclear receptor corepressor complex N-CoR contains components of the mammalian SWI/SNF complex and the corepressor KAP-1. www.ncbi.nlm.ni...
PMID 15951569 View Gene Set 0.001947 75 0.04034 121 Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. www.ncbi.nlm.ni...
PMID 11266503 View Gene Set 0.002004 13 0.04084 122 Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140. www.ncbi.nlm.ni...
PMID 12637327 View Gene Set 0.001996 12 0.04084 122 Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc cyclins and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells. www.ncbi.nlm.ni...
PMID 16097034 View Gene Set 0.002032 36 0.04108 124 Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC. www.ncbi.nlm.ni...
PMID 11285280 View Gene Set 0.00216 62 0.04332 125 Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. www.ncbi.nlm.ni...
PMID 15231747 View Gene Set 0.00223 212 0.04437 126 A protein interaction framework for human mRNA degradation. www.ncbi.nlm.ni...
PMID 11060040 View Gene Set 0.002351 15 0.04583 127 Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. www.ncbi.nlm.ni...
PMID 16109376 View Gene Set 0.002354 17 0.04583 127 The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. www.ncbi.nlm.ni...
PMID 20023658 View Gene Set 0.002358 13 0.04583 127 Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate. www.ncbi.nlm.ni...
PMID 7776974 View Gene Set 0.002376 18 0.04583 130 Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. www.ncbi.nlm.ni...
PMID 10830953 View Gene Set 0.002421 262 0.04634 131 The DNA sequence of human chromosome 21. www.ncbi.nlm.ni...
PMID 10567404 View Gene Set 0.002539 17 0.0475 132 A nuclear factor ASC-2 as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo. www.ncbi.nlm.ni...
PMID 15456888 View Gene Set 0.002535 24 0.0475 132 The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. www.ncbi.nlm.ni...
PMID 16094384 View Gene Set 0.002536 80 0.0475 132 Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. www.ncbi.nlm.ni...
PMID 11073998 View Gene Set 0.002619 15 0.04864 135 TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture. www.ncbi.nlm.ni...
PMID 19596235 View Gene Set 0.00271 85 0.04996 136 Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. www.ncbi.nlm.ni...

Gene Set Collection: ChromosomalTiles5Mb

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null chr5_65-70Mb View Gene Set 2.584e-05 13 0.01882 1 Genomic tile: chr5 ; 65000001-70000001 Mb genome.ucsc.edu...
Null chr6_15-20Mb View Gene Set 4.935e-05 12 0.01882 1 Genomic tile: chr6 ; 15000001-20000001 Mb genome.ucsc.edu...
Null chr6_80-85Mb View Gene Set 5.068e-05 14 0.01882 1 Genomic tile: chr6 ; 80000001-85000001 Mb genome.ucsc.edu...

Gene Set Collection: Prosite

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null PS50102 View Gene Set 3.719e-12 229 2.734e-09 1 RRM expasy.org/pros...
Null PS50082 View Gene Set 3.658e-08 233 8.961e-06 2 WD_REPEATS_2 expasy.org/pros...
Null PS50294 View Gene Set 2.8e-08 245 8.961e-06 2 WD_REPEATS_REGION expasy.org/pros...
Null PS50016 View Gene Set 8.399e-08 78 1.543e-05 4 ZF_PHD_2 expasy.org/pros...
Null PS00678 View Gene Set 1.752e-06 168 0.0002575 5 WD_REPEATS_1 expasy.org/pros...
Null PS00107 View Gene Set 8.912e-06 384 0.000655 6 PROTEIN_KINASE_ATP expasy.org/pros...
Null PS00108 View Gene Set 5.525e-06 316 0.000655 6 PROTEIN_KINASE_ST expasy.org/pros...
Null PS00633 View Gene Set 6.633e-06 26 0.000655 6 BROMODOMAIN_1 expasy.org/pros...
Null PS01359 View Gene Set 8.064e-06 72 0.000655 6 ZF_PHD_1 expasy.org/pros...
Null PS50011 View Gene Set 7.677e-06 493 0.000655 6 PROTEIN_KINASE_DOM expasy.org/pros...
Null PS50014 View Gene Set 1.159e-05 41 0.0007745 11 BROMODOMAIN_2 expasy.org/pros...
Null PS50089 View Gene Set 2.097e-05 301 0.001285 12 ZF_RING_2 expasy.org/pros...
Null PS50127 View Gene Set 3.15e-05 41 0.001781 13 UBIQUITIN_CONJUGAT_2 expasy.org/pros...
Null PS00036 View Gene Set 9.707e-05 35 0.005096 14 BZIP_BASIC expasy.org/pros...
Null PS50812 View Gene Set 0.0002787 22 0.01365 15 PWWP expasy.org/pros...
Null PS50097 View Gene Set 0.0003191 141 0.01466 16 BTB expasy.org/pros...
Null PS50800 View Gene Set 0.0003775 23 0.01632 17 SAP expasy.org/pros...
Null PS50217 View Gene Set 0.0004439 52 0.01813 18 BZIP expasy.org/pros...
Null PS50051 View Gene Set 0.0005393 8 0.02086 19 MCM_2 expasy.org/pros...
Null PS50237 View Gene Set 0.0005979 29 0.02197 20 HECT expasy.org/pros...
Null PS00183 View Gene Set 0.0009048 25 0.03167 21 UBIQUITIN_CONJUGAT_1 expasy.org/pros...
Null PS50202 View Gene Set 0.0009978 7 0.03333 22 MSP expasy.org/pros...
Null PS00847 View Gene Set 0.001313 6 0.03825 23 MCM_1 expasy.org/pros...
Null PS00972 View Gene Set 0.001207 72 0.03825 23 UCH_2_1 expasy.org/pros...
Null PS50005 View Gene Set 0.001353 114 0.03825 23 TPR expasy.org/pros...
Null PS50103 View Gene Set 0.00134 60 0.03825 23 ZF_C3H1 expasy.org/pros...
Null PS00292 View Gene Set 0.0017 10 0.04542 27 CYCLINS expasy.org/pros...
Null PS50235 View Gene Set 0.001778 83 0.04542 27 UCH_2_3 expasy.org/pros...
Null PS50293 View Gene Set 0.001792 134 0.04542 27 TPR_REGION expasy.org/pros...
Null PS50896 View Gene Set 0.001955 28 0.04789 30 LISH expasy.org/pros...
Null PS50868 View Gene Set 0.002046 16 0.04851 31 POST_SET expasy.org/pros...

Gene Set Collection: Enzyme

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null EC:6.3.2.19 View Gene Set 6.246e-05 79 0.009869 1 Ubiquitin--protein ligase expasy.org/enzy...

Gene Set Collection: ppi.BIND

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.SMAD4 View Gene Set 0.0001744 10 0.02573 1 Protein-protein-interaction for SMAD4 www.ncbi.nlm.ni...
Null ppi.RB1 View Gene Set 0.0002723 44 0.02573 1 Protein-protein-interaction for RB1 www.ncbi.nlm.ni...
Null ppi.CFLAR View Gene Set 0.0004389 6 0.02765 3 Protein-protein-interaction for CFLAR www.ncbi.nlm.ni...

Gene Set Collection: ppi.BioGRID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.155871 View Gene Set 3.078e-13 236 7.069e-10 1 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 1.045e-06 147 0.0008929 2 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.SRC View Gene Set 1.166e-06 91 0.0008929 2 Protein-protein-interaction for SRC www.ncbi.nlm.ni...
Null ppi.ING5 View Gene Set 1.869e-06 20 0.001073 4 Protein-protein-interaction for ING5 www.ncbi.nlm.ni...
Null ppi.RNPS1 View Gene Set 3.873e-06 38 0.001779 5 Protein-protein-interaction for RNPS1 www.ncbi.nlm.ni...
Null ppi.SRRM1 View Gene Set 5.577e-06 64 0.001988 6 Protein-protein-interaction for SRRM1 www.ncbi.nlm.ni...
Null ppi.CDT1 View Gene Set 6.059e-06 37 0.001988 6 Protein-protein-interaction for CDT1 www.ncbi.nlm.ni...
Null ppi.MED30 View Gene Set 1.522e-05 26 0.004371 8 Protein-protein-interaction for MED30 www.ncbi.nlm.ni...
Null ppi.MED21 View Gene Set 2.166e-05 21 0.005528 9 Protein-protein-interaction for MED21 www.ncbi.nlm.ni...
Null ppi.WBP4 View Gene Set 2.992e-05 35 0.006872 10 Protein-protein-interaction for WBP4 www.ncbi.nlm.ni...
Null ppi.HDAC3 View Gene Set 4.043e-05 92 0.008205 11 Protein-protein-interaction for HDAC3 www.ncbi.nlm.ni...
Null ppi.CDC16 View Gene Set 4.286e-05 10 0.008205 11 Protein-protein-interaction for CDC16 www.ncbi.nlm.ni...
Null ppi.PCNA View Gene Set 4.689e-05 40 0.008284 13 Protein-protein-interaction for PCNA www.ncbi.nlm.ni...
Null ppi.U2AF2 View Gene Set 8.626e-05 14 0.01178 14 Protein-protein-interaction for U2AF2 www.ncbi.nlm.ni...
Null ppi.MED9 View Gene Set 7.689e-05 31 0.01178 14 Protein-protein-interaction for MED9 www.ncbi.nlm.ni...
Null ppi.ITCH View Gene Set 8.716e-05 57 0.01178 14 Protein-protein-interaction for ITCH www.ncbi.nlm.ni...
Null ppi.LNX1 View Gene Set 8.166e-05 41 0.01178 14 Protein-protein-interaction for LNX1 www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 0.0001002 38 0.01279 18 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.MED28 View Gene Set 0.0001471 37 0.01779 19 Protein-protein-interaction for MED28 www.ncbi.nlm.ni...
Null ppi.MYC View Gene Set 0.0001591 42 0.01827 20 Protein-protein-interaction for MYC www.ncbi.nlm.ni...
Null ppi.YWHAQ View Gene Set 0.0001826 61 0.01917 21 Protein-protein-interaction for YWHAQ www.ncbi.nlm.ni...
Null ppi.MED19 View Gene Set 0.0001836 45 0.01917 21 Protein-protein-interaction for MED19 www.ncbi.nlm.ni...
Null ppi.GABARAPL2 View Gene Set 0.0002403 28 0.02208 23 Protein-protein-interaction for GABARAPL2 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 0.0002234 12 0.02208 23 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.NUP153 View Gene Set 0.0002334 11 0.02208 23 Protein-protein-interaction for NUP153 www.ncbi.nlm.ni...
Null ppi.LSM4 View Gene Set 0.0002647 10 0.02339 26 Protein-protein-interaction for LSM4 www.ncbi.nlm.ni...
Null ppi.SIN3A View Gene Set 0.0002856 104 0.0243 27 Protein-protein-interaction for SIN3A www.ncbi.nlm.ni...
Null ppi.MCM7 View Gene Set 0.0002973 11 0.02439 28 Protein-protein-interaction for MCM7 www.ncbi.nlm.ni...
Null ppi.TBP View Gene Set 0.0003436 67 0.02546 29 Protein-protein-interaction for TBP www.ncbi.nlm.ni...
Null ppi.72462 View Gene Set 0.0003407 42 0.02546 29 Protein-protein-interaction for 72462 www.ncbi.nlm.ni...
Null ppi.PIAS1 View Gene Set 0.0003255 25 0.02546 29 Protein-protein-interaction for PIAS1 www.ncbi.nlm.ni...
Null ppi.RBMX View Gene Set 0.0003696 15 0.02573 32 Protein-protein-interaction for RBMX www.ncbi.nlm.ni...
Null ppi.POLR2A View Gene Set 0.000364 25 0.02573 32 Protein-protein-interaction for POLR2A www.ncbi.nlm.ni...
Null ppi.PIAS3 View Gene Set 0.0004409 19 0.02624 34 Protein-protein-interaction for PIAS3 www.ncbi.nlm.ni...
Null ppi.KLF1 View Gene Set 0.0004965 13 0.02624 34 Protein-protein-interaction for KLF1 www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 0.0005053 10 0.02624 34 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.CSNK2B View Gene Set 0.000518 12 0.02624 34 Protein-protein-interaction for CSNK2B www.ncbi.nlm.ni...
Null ppi.PDS5A View Gene Set 0.0005171 6 0.02624 34 Protein-protein-interaction for PDS5A www.ncbi.nlm.ni...
Null ppi.HDAC2 View Gene Set 0.0005333 34 0.02624 34 Protein-protein-interaction for HDAC2 www.ncbi.nlm.ni...
Null ppi.USP50 View Gene Set 0.0005713 22 0.02624 34 Protein-protein-interaction for USP50 www.ncbi.nlm.ni...
Null ppi.SMAD4 View Gene Set 0.0005285 27 0.02624 34 Protein-protein-interaction for SMAD4 www.ncbi.nlm.ni...
Null ppi.NEDD9 View Gene Set 0.0004968 15 0.02624 34 Protein-protein-interaction for NEDD9 www.ncbi.nlm.ni...
Null ppi.ORC1L View Gene Set 0.0005703 9 0.02624 34 Protein-protein-interaction for ORC1L www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 0.0005281 53 0.02624 34 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.SPI1 View Gene Set 0.0004129 24 0.02624 34 Protein-protein-interaction for SPI1 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 0.000534 168 0.02624 34 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.USP7 View Gene Set 0.000539 24 0.02624 34 Protein-protein-interaction for USP7 www.ncbi.nlm.ni...
Null ppi.CDC7 View Gene Set 0.0004591 7 0.02624 34 Protein-protein-interaction for CDC7 www.ncbi.nlm.ni...
Null ppi.GTF3C3 View Gene Set 0.0004741 11 0.02624 34 Protein-protein-interaction for GTF3C3 www.ncbi.nlm.ni...
Null ppi.CLOCK View Gene Set 0.0005514 6 0.02624 34 Protein-protein-interaction for CLOCK www.ncbi.nlm.ni...
Null ppi.RARA View Gene Set 0.0005921 21 0.0264 51 Protein-protein-interaction for RARA www.ncbi.nlm.ni...
Null ppi.NCOR1 View Gene Set 0.0005978 84 0.0264 51 Protein-protein-interaction for NCOR1 www.ncbi.nlm.ni...
Null ppi.CDCA3 View Gene Set 0.0006246 6 0.02707 53 Protein-protein-interaction for CDCA3 www.ncbi.nlm.ni...
Null ppi.PUF60 View Gene Set 0.0006533 31 0.02728 54 Protein-protein-interaction for PUF60 www.ncbi.nlm.ni...
Null ppi.ZBTB16 View Gene Set 0.0006508 38 0.02728 54 Protein-protein-interaction for ZBTB16 www.ncbi.nlm.ni...
Null ppi.KBTBD7 View Gene Set 0.0006687 28 0.02743 56 Protein-protein-interaction for KBTBD7 www.ncbi.nlm.ni...
Null ppi.RUVBL2 View Gene Set 0.0008161 64 0.03249 57 Protein-protein-interaction for RUVBL2 www.ncbi.nlm.ni...
Null ppi.WDR20 View Gene Set 0.0008204 17 0.03249 57 Protein-protein-interaction for WDR20 www.ncbi.nlm.ni...
Null ppi.USP20 View Gene Set 0.0008472 29 0.03298 59 Protein-protein-interaction for USP20 www.ncbi.nlm.ni...
Null ppi.C19orf62 View Gene Set 0.000906 29 0.03469 60 Protein-protein-interaction for C19orf62 www.ncbi.nlm.ni...
Null ppi.WWOX View Gene Set 0.0009314 19 0.03507 61 Protein-protein-interaction for WWOX www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 0.001021 19 0.03572 62 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.JUN View Gene Set 0.00104 41 0.03572 62 Protein-protein-interaction for JUN www.ncbi.nlm.ni...
Null ppi.WDR48 View Gene Set 0.001047 52 0.03572 62 Protein-protein-interaction for WDR48 www.ncbi.nlm.ni...
Null ppi.SMARCC1 View Gene Set 0.001019 26 0.03572 62 Protein-protein-interaction for SMARCC1 www.ncbi.nlm.ni...
Null ppi.TAF10 View Gene Set 0.001022 27 0.03572 62 Protein-protein-interaction for TAF10 www.ncbi.nlm.ni...
Null ppi.NUP214 View Gene Set 0.001044 7 0.03572 62 Protein-protein-interaction for NUP214 www.ncbi.nlm.ni...
Null ppi.MED10 View Gene Set 0.001058 44 0.03572 62 Protein-protein-interaction for MED10 www.ncbi.nlm.ni...
Null ppi.MED18 View Gene Set 0.0011 9 0.03608 69 Protein-protein-interaction for MED18 www.ncbi.nlm.ni...
Null ppi.TAF1D View Gene Set 0.001087 21 0.03608 69 Protein-protein-interaction for TAF1D www.ncbi.nlm.ni...
Null ppi.MAP1LC3A View Gene Set 0.001131 30 0.03659 71 Protein-protein-interaction for MAP1LC3A www.ncbi.nlm.ni...
Null ppi.SF3A3 View Gene Set 0.001183 7 0.03686 72 Protein-protein-interaction for SF3A3 www.ncbi.nlm.ni...
Null ppi.STAT3 View Gene Set 0.001187 57 0.03686 72 Protein-protein-interaction for STAT3 www.ncbi.nlm.ni...
Null ppi.SNIP1 View Gene Set 0.001164 9 0.03686 72 Protein-protein-interaction for SNIP1 www.ncbi.nlm.ni...
Null ppi.TDG View Gene Set 0.001212 13 0.03713 75 Protein-protein-interaction for TDG www.ncbi.nlm.ni...
Null ppi.HIST4H4 View Gene Set 0.001317 21 0.03781 76 Protein-protein-interaction for HIST4H4 www.ncbi.nlm.ni...
Null ppi.ANAPC2 View Gene Set 0.001301 6 0.03781 76 Protein-protein-interaction for ANAPC2 www.ncbi.nlm.ni...
Null ppi.PSMC2 View Gene Set 0.001284 6 0.03781 76 Protein-protein-interaction for PSMC2 www.ncbi.nlm.ni...
Null ppi.RB1 View Gene Set 0.001298 46 0.03781 76 Protein-protein-interaction for RB1 www.ncbi.nlm.ni...
Null ppi.PRAM1 View Gene Set 0.001293 10 0.03781 76 Protein-protein-interaction for PRAM1 www.ncbi.nlm.ni...
Null ppi.STUB1 View Gene Set 0.001342 43 0.03807 81 Protein-protein-interaction for STUB1 www.ncbi.nlm.ni...
Null ppi.SF3B3 View Gene Set 0.001381 16 0.0384 82 Protein-protein-interaction for SF3B3 www.ncbi.nlm.ni...
Null ppi.NR0B2 View Gene Set 0.001388 23 0.0384 82 Protein-protein-interaction for NR0B2 www.ncbi.nlm.ni...
Null ppi.SRPK2 View Gene Set 0.001439 7 0.03935 84 Protein-protein-interaction for SRPK2 www.ncbi.nlm.ni...
Null ppi.MED29 View Gene Set 0.001481 37 0.04003 85 Protein-protein-interaction for MED29 www.ncbi.nlm.ni...
Null ppi.ESR1 View Gene Set 0.001608 22 0.0408 86 Protein-protein-interaction for ESR1 www.ncbi.nlm.ni...
Null ppi.PIM1 View Gene Set 0.001634 8 0.0408 86 Protein-protein-interaction for PIM1 www.ncbi.nlm.ni...
Null ppi.STAT1 View Gene Set 0.001577 31 0.0408 86 Protein-protein-interaction for STAT1 www.ncbi.nlm.ni...
Null ppi.VDR View Gene Set 0.001608 26 0.0408 86 Protein-protein-interaction for VDR www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 0.001599 43 0.0408 86 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.TRRAP View Gene Set 0.001621 21 0.0408 86 Protein-protein-interaction for TRRAP www.ncbi.nlm.ni...
Null ppi.SPAG9 View Gene Set 0.001626 9 0.0408 86 Protein-protein-interaction for SPAG9 www.ncbi.nlm.ni...
Null ppi.CARM1 View Gene Set 0.001715 32 0.04191 93 Protein-protein-interaction for CARM1 www.ncbi.nlm.ni...
Null ppi.SMAD3 View Gene Set 0.001711 41 0.04191 93 Protein-protein-interaction for SMAD3 www.ncbi.nlm.ni...
Null ppi.TCF12 View Gene Set 0.001745 12 0.04211 95 Protein-protein-interaction for TCF12 www.ncbi.nlm.ni...
Null ppi.CFLAR View Gene Set 0.001762 17 0.04211 95 Protein-protein-interaction for CFLAR www.ncbi.nlm.ni...
Null ppi.KAT2B View Gene Set 0.001778 71 0.04211 95 Protein-protein-interaction for KAT2B www.ncbi.nlm.ni...
Null ppi.TBPL1 View Gene Set 0.001812 12 0.04248 98 Protein-protein-interaction for TBPL1 www.ncbi.nlm.ni...
Null ppi.ANAPC1 View Gene Set 0.001874 15 0.04304 99 Protein-protein-interaction for ANAPC1 www.ncbi.nlm.ni...
Null ppi.SMC3 View Gene Set 0.001866 17 0.04304 99 Protein-protein-interaction for SMC3 www.ncbi.nlm.ni...
Null ppi.SUMO2 View Gene Set 0.001998 50 0.04544 101 Protein-protein-interaction for SUMO2 www.ncbi.nlm.ni...
Null ppi.PPARGC1A View Gene Set 0.002088 33 0.04633 102 Protein-protein-interaction for PPARGC1A www.ncbi.nlm.ni...
Null ppi.E2F1 View Gene Set 0.002097 9 0.04633 102 Protein-protein-interaction for E2F1 www.ncbi.nlm.ni...
Null ppi.RFWD2 View Gene Set 0.002087 26 0.04633 102 Protein-protein-interaction for RFWD2 www.ncbi.nlm.ni...
Null ppi.NUP50 View Gene Set 0.002293 6 0.04787 105 Protein-protein-interaction for NUP50 www.ncbi.nlm.ni...
Null ppi.SIAH1 View Gene Set 0.002241 14 0.04787 105 Protein-protein-interaction for SIAH1 www.ncbi.nlm.ni...
Null ppi.SMARCA4 View Gene Set 0.002216 59 0.04787 105 Protein-protein-interaction for SMARCA4 www.ncbi.nlm.ni...
Null ppi.STAT2 View Gene Set 0.00229 10 0.04787 105 Protein-protein-interaction for STAT2 www.ncbi.nlm.ni...
Null ppi.ZEB1 View Gene Set 0.002223 6 0.04787 105 Protein-protein-interaction for ZEB1 www.ncbi.nlm.ni...
Null ppi.TYK2 View Gene Set 0.002267 14 0.04787 105 Protein-protein-interaction for TYK2 www.ncbi.nlm.ni...
Null ppi.MEF2C View Gene Set 0.002347 6 0.04814 111 Protein-protein-interaction for MEF2C www.ncbi.nlm.ni...
Null ppi.C20orf20 View Gene Set 0.002333 15 0.04814 111 Protein-protein-interaction for C20orf20 www.ncbi.nlm.ni...
Null ppi.SF3B2 View Gene Set 0.002389 11 0.04823 113 Protein-protein-interaction for SF3B2 www.ncbi.nlm.ni...
Null ppi.PAF1 View Gene Set 0.002414 6 0.04823 113 Protein-protein-interaction for PAF1 www.ncbi.nlm.ni...
Null ppi.NCOA3 View Gene Set 0.002435 35 0.04823 113 Protein-protein-interaction for NCOA3 www.ncbi.nlm.ni...
Null ppi.CASP9 View Gene Set 0.002417 9 0.04823 113 Protein-protein-interaction for CASP9 www.ncbi.nlm.ni...
Null ppi.SS18L1 View Gene Set 0.002463 15 0.04836 117 Protein-protein-interaction for SS18L1 www.ncbi.nlm.ni...

Gene Set Collection: ppi.HPRD

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.SNIP1 View Gene Set 3.468e-06 27 0.008233 1 Protein-protein-interaction for SNIP1 www.ncbi.nlm.ni...
Null ppi.GMEB1 View Gene Set 2.127e-05 8 0.008417 2 Protein-protein-interaction for GMEB1 www.ncbi.nlm.ni...
Null ppi.MCM7 View Gene Set 1.497e-05 11 0.008417 2 Protein-protein-interaction for MCM7 www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 1.736e-05 55 0.008417 2 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.VDR View Gene Set 1.581e-05 22 0.008417 2 Protein-protein-interaction for VDR www.ncbi.nlm.ni...
Null ppi.LNX1 View Gene Set 1.823e-05 43 0.008417 2 Protein-protein-interaction for LNX1 www.ncbi.nlm.ni...
Null ppi.SFRS12 View Gene Set 3.12e-05 49 0.009306 7 Protein-protein-interaction for SFRS12 www.ncbi.nlm.ni...
Null ppi.MYC View Gene Set 3.136e-05 28 0.009306 7 Protein-protein-interaction for MYC www.ncbi.nlm.ni...
Null ppi.PABPC1 View Gene Set 4.022e-05 21 0.01061 9 Protein-protein-interaction for PABPC1 www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 6.531e-05 14 0.0155 10 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.MCM10 View Gene Set 8.539e-05 25 0.01843 11 Protein-protein-interaction for MCM10 www.ncbi.nlm.ni...
Null ppi.RB1 View Gene Set 0.0001189 77 0.02352 12 Protein-protein-interaction for RB1 www.ncbi.nlm.ni...
Null ppi.PCNA View Gene Set 0.0001739 33 0.03176 13 Protein-protein-interaction for PCNA www.ncbi.nlm.ni...
Null ppi.NCOA2 View Gene Set 0.0003586 40 0.04695 14 Protein-protein-interaction for NCOA2 www.ncbi.nlm.ni...
Null ppi.NUP62 View Gene Set 0.0004031 19 0.04695 14 Protein-protein-interaction for NUP62 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 0.000364 11 0.04695 14 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.EIF4ENIF1 View Gene Set 0.0003848 7 0.04695 14 Protein-protein-interaction for EIF4ENIF1 www.ncbi.nlm.ni...
Null ppi.KIAA1377 View Gene Set 0.0003179 62 0.04695 14 Protein-protein-interaction for KIAA1377 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 0.0002929 166 0.04695 14 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.CDC7 View Gene Set 0.0003511 13 0.04695 14 Protein-protein-interaction for CDC7 www.ncbi.nlm.ni...
Null ppi.HDAC3 View Gene Set 0.0004153 40 0.04695 14 Protein-protein-interaction for HDAC3 www.ncbi.nlm.ni...
Null ppi.STAT3 View Gene Set 0.0004577 73 0.04725 22 Protein-protein-interaction for STAT3 www.ncbi.nlm.ni...
Null ppi.YWHAG View Gene Set 0.0004551 106 0.04725 22 Protein-protein-interaction for YWHAG www.ncbi.nlm.ni...
Null ppi.SRC View Gene Set 0.0004944 134 0.0489 24 Protein-protein-interaction for SRC www.ncbi.nlm.ni...

Gene Set Collection: ppi.anyDB

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.155871 View Gene Set 1.273e-12 251 4.577e-09 1 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 9.131e-07 96 0.001252 2 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 1.045e-06 147 0.001252 2 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.SNIP1 View Gene Set 2.117e-06 28 0.001902 4 Protein-protein-interaction for SNIP1 www.ncbi.nlm.ni...
Null ppi.SRC View Gene Set 3.84e-06 171 0.0023 5 Protein-protein-interaction for SRC www.ncbi.nlm.ni...
Null ppi.CDT1 View Gene Set 3.776e-06 42 0.0023 5 Protein-protein-interaction for CDT1 www.ncbi.nlm.ni...
Null ppi.SRRM1 View Gene Set 7.821e-06 66 0.003514 7 Protein-protein-interaction for SRRM1 www.ncbi.nlm.ni...
Null ppi.RNPS1 View Gene Set 7.403e-06 44 0.003514 7 Protein-protein-interaction for RNPS1 www.ncbi.nlm.ni...
Null ppi.RARA View Gene Set 1.015e-05 28 0.003659 9 Protein-protein-interaction for RARA www.ncbi.nlm.ni...
Null ppi.VDR View Gene Set 1.09e-05 37 0.003659 9 Protein-protein-interaction for VDR www.ncbi.nlm.ni...
Null ppi.HDAC3 View Gene Set 1.12e-05 102 0.003659 9 Protein-protein-interaction for HDAC3 www.ncbi.nlm.ni...
Null ppi.MED30 View Gene Set 1.522e-05 26 0.004559 12 Protein-protein-interaction for MED30 www.ncbi.nlm.ni...
Null ppi.LNX1 View Gene Set 1.823e-05 43 0.00504 13 Protein-protein-interaction for LNX1 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 2.113e-05 15 0.005424 14 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.WBP4 View Gene Set 2.992e-05 35 0.006324 15 Protein-protein-interaction for WBP4 www.ncbi.nlm.ni...
Null ppi.SFRS12 View Gene Set 2.866e-05 50 0.006324 15 Protein-protein-interaction for SFRS12 www.ncbi.nlm.ni...
Null ppi.MYC View Gene Set 2.797e-05 56 0.006324 15 Protein-protein-interaction for MYC www.ncbi.nlm.ni...
Null ppi.MED9 View Gene Set 3.456e-05 33 0.0069 18 Protein-protein-interaction for MED9 www.ncbi.nlm.ni...
Null ppi.MCM10 View Gene Set 3.889e-05 28 0.006988 19 Protein-protein-interaction for MCM10 www.ncbi.nlm.ni...
Null ppi.ING5 View Gene Set 3.852e-05 25 0.006988 19 Protein-protein-interaction for ING5 www.ncbi.nlm.ni...
Null ppi.GMEB1 View Gene Set 4.275e-05 9 0.007216 21 Protein-protein-interaction for GMEB1 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 4.417e-05 220 0.007216 21 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.ORC1L View Gene Set 5.561e-05 11 0.008689 23 Protein-protein-interaction for ORC1L www.ncbi.nlm.ni...
Null ppi.NUP62 View Gene Set 6.002e-05 25 0.008988 24 Protein-protein-interaction for NUP62 www.ncbi.nlm.ni...
Null ppi.MED28 View Gene Set 6.338e-05 40 0.009111 25 Protein-protein-interaction for MED28 www.ncbi.nlm.ni...
Null ppi.GABARAPL2 View Gene Set 6.771e-05 31 0.009359 26 Protein-protein-interaction for GABARAPL2 www.ncbi.nlm.ni...
Null ppi.NCOA3 View Gene Set 7.437e-05 59 0.0099 27 Protein-protein-interaction for NCOA3 www.ncbi.nlm.ni...
Null ppi.PCNA View Gene Set 7.751e-05 47 0.009949 28 Protein-protein-interaction for PCNA www.ncbi.nlm.ni...
Null ppi.PABPC1 View Gene Set 8.599e-05 37 0.0103 29 Protein-protein-interaction for PABPC1 www.ncbi.nlm.ni...
Null ppi.MED21 View Gene Set 8.494e-05 27 0.0103 29 Protein-protein-interaction for MED21 www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 0.0001296 17 0.01411 31 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.RUVBL2 View Gene Set 0.000127 72 0.01411 31 Protein-protein-interaction for RUVBL2 www.ncbi.nlm.ni...
Null ppi.MCM7 View Gene Set 0.0001271 12 0.01411 31 Protein-protein-interaction for MCM7 www.ncbi.nlm.ni...
Null ppi.NCOA2 View Gene Set 0.0001488 52 0.01573 34 Protein-protein-interaction for NCOA2 www.ncbi.nlm.ni...
Null ppi.USP7 View Gene Set 0.0001563 32 0.01605 35 Protein-protein-interaction for USP7 www.ncbi.nlm.ni...
Null ppi.RB1 View Gene Set 0.000162 93 0.01617 36 Protein-protein-interaction for RB1 www.ncbi.nlm.ni...
Null ppi.NUP214 View Gene Set 0.0002268 11 0.02145 37 Protein-protein-interaction for NUP214 www.ncbi.nlm.ni...
Null ppi.NUP153 View Gene Set 0.000226 16 0.02145 37 Protein-protein-interaction for NUP153 www.ncbi.nlm.ni...
Null ppi.STUB1 View Gene Set 0.0002799 55 0.0215 39 Protein-protein-interaction for STUB1 www.ncbi.nlm.ni...
Null ppi.KLF1 View Gene Set 0.0002453 14 0.0215 39 Protein-protein-interaction for KLF1 www.ncbi.nlm.ni...
Null ppi.NUP50 View Gene Set 0.0002466 8 0.0215 39 Protein-protein-interaction for NUP50 www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 0.0002866 33 0.0215 39 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.LSM4 View Gene Set 0.0002647 11 0.0215 39 Protein-protein-interaction for LSM4 www.ncbi.nlm.ni...
Null ppi.SIN3A View Gene Set 0.0002524 116 0.0215 39 Protein-protein-interaction for SIN3A www.ncbi.nlm.ni...
Null ppi.ORC5L View Gene Set 0.0002483 11 0.0215 39 Protein-protein-interaction for ORC5L www.ncbi.nlm.ni...
Null ppi.TAF11 View Gene Set 0.0002796 19 0.0215 39 Protein-protein-interaction for TAF11 www.ncbi.nlm.ni...
Null ppi.XPO1 View Gene Set 0.0002872 43 0.0215 39 Protein-protein-interaction for XPO1 www.ncbi.nlm.ni...
Null ppi.YWHAG View Gene Set 0.0002733 119 0.0215 39 Protein-protein-interaction for YWHAG www.ncbi.nlm.ni...
Null ppi.72462 View Gene Set 0.0003407 42 0.02499 49 Protein-protein-interaction for 72462 www.ncbi.nlm.ni...
Null ppi.TPX2 View Gene Set 0.000369 5 0.02516 50 Protein-protein-interaction for TPX2 www.ncbi.nlm.ni...
Null ppi.SF3B1 View Gene Set 0.0003843 31 0.02516 50 Protein-protein-interaction for SF3B1 www.ncbi.nlm.ni...
Null ppi.RBMX View Gene Set 0.0003696 15 0.02516 50 Protein-protein-interaction for RBMX www.ncbi.nlm.ni...
Null ppi.HIPK2 View Gene Set 0.000392 33 0.02516 50 Protein-protein-interaction for HIPK2 www.ncbi.nlm.ni...
Null ppi.EIF4ENIF1 View Gene Set 0.0003848 7 0.02516 50 Protein-protein-interaction for EIF4ENIF1 www.ncbi.nlm.ni...
Null ppi.SUMO2 View Gene Set 0.0003858 55 0.02516 50 Protein-protein-interaction for SUMO2 www.ncbi.nlm.ni...
Null ppi.CDC7 View Gene Set 0.0003511 13 0.02516 50 Protein-protein-interaction for CDC7 www.ncbi.nlm.ni...
Null ppi.SF3A3 View Gene Set 0.0004109 8 0.02591 57 Protein-protein-interaction for SF3A3 www.ncbi.nlm.ni...
Null ppi.JUN View Gene Set 0.000422 55 0.02615 58 Protein-protein-interaction for JUN www.ncbi.nlm.ni...
Null ppi.USP20 View Gene Set 0.0005914 30 0.03099 59 Protein-protein-interaction for USP20 www.ncbi.nlm.ni...
Null ppi.U2AF2 View Gene Set 0.0005889 23 0.03099 59 Protein-protein-interaction for U2AF2 www.ncbi.nlm.ni...
Null ppi.MED19 View Gene Set 0.0005452 47 0.03099 59 Protein-protein-interaction for MED19 www.ncbi.nlm.ni...
Null ppi.PUF60 View Gene Set 0.0005545 35 0.03099 59 Protein-protein-interaction for PUF60 www.ncbi.nlm.ni...
Null ppi.PDS5A View Gene Set 0.0005171 6 0.03099 59 Protein-protein-interaction for PDS5A www.ncbi.nlm.ni...
Null ppi.HDAC2 View Gene Set 0.0005377 36 0.03099 59 Protein-protein-interaction for HDAC2 www.ncbi.nlm.ni...
Null ppi.USP50 View Gene Set 0.0005713 22 0.03099 59 Protein-protein-interaction for USP50 www.ncbi.nlm.ni...
Null ppi.NEDD9 View Gene Set 0.000595 16 0.03099 59 Protein-protein-interaction for NEDD9 www.ncbi.nlm.ni...
Null ppi.ANAPC7 View Gene Set 0.0005297 15 0.03099 59 Protein-protein-interaction for ANAPC7 www.ncbi.nlm.ni...
Null ppi.KIAA1377 View Gene Set 0.0005496 64 0.03099 59 Protein-protein-interaction for KIAA1377 www.ncbi.nlm.ni...
Null ppi.TBP View Gene Set 0.0005917 80 0.03099 59 Protein-protein-interaction for TBP www.ncbi.nlm.ni...
Null ppi.CDCA3 View Gene Set 0.0006246 6 0.03207 70 Protein-protein-interaction for CDCA3 www.ncbi.nlm.ni...
Null ppi.HOXA10 View Gene Set 0.0006634 6 0.03247 71 Protein-protein-interaction for HOXA10 www.ncbi.nlm.ni...
Null ppi.TYK2 View Gene Set 0.0006763 23 0.03247 71 Protein-protein-interaction for TYK2 www.ncbi.nlm.ni...
Null ppi.KBTBD7 View Gene Set 0.0006687 28 0.03247 71 Protein-protein-interaction for KBTBD7 www.ncbi.nlm.ni...
Null ppi.CDC16 View Gene Set 0.0006793 14 0.03247 71 Protein-protein-interaction for CDC16 www.ncbi.nlm.ni...
Null ppi.GTF3C3 View Gene Set 0.0006579 12 0.03247 71 Protein-protein-interaction for GTF3C3 www.ncbi.nlm.ni...
Null ppi.NCOR1 View Gene Set 0.0006866 95 0.03247 71 Protein-protein-interaction for NCOR1 www.ncbi.nlm.ni...
Null ppi.ITCH View Gene Set 0.0007062 64 0.03296 77 Protein-protein-interaction for ITCH www.ncbi.nlm.ni...
Null ppi.NR3C1 View Gene Set 0.000724 19 0.03336 78 Protein-protein-interaction for NR3C1 www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 0.0007748 46 0.03481 79 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.MYOD1 View Gene Set 0.0007655 32 0.03481 79 Protein-protein-interaction for MYOD1 www.ncbi.nlm.ni...
Null ppi.SF3B2 View Gene Set 0.0007922 12 0.03491 81 Protein-protein-interaction for SF3B2 www.ncbi.nlm.ni...
Null ppi.TAF1 View Gene Set 0.0008165 24 0.03491 81 Protein-protein-interaction for TAF1 www.ncbi.nlm.ni...
Null ppi.MAP1LC3A View Gene Set 0.0008256 33 0.03491 81 Protein-protein-interaction for MAP1LC3A www.ncbi.nlm.ni...
Null ppi.CFLAR View Gene Set 0.0008203 26 0.03491 81 Protein-protein-interaction for CFLAR www.ncbi.nlm.ni...
Null ppi.WDR20 View Gene Set 0.0008204 17 0.03491 81 Protein-protein-interaction for WDR20 www.ncbi.nlm.ni...
Null ppi.FOS View Gene Set 0.0008408 20 0.03514 86 Protein-protein-interaction for FOS www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 0.0008529 12 0.03523 87 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.NDC80 View Gene Set 0.0009247 10 0.0357 88 Protein-protein-interaction for NDC80 www.ncbi.nlm.ni...
Null ppi.ORC6L View Gene Set 0.0009338 15 0.0357 88 Protein-protein-interaction for ORC6L www.ncbi.nlm.ni...
Null ppi.C19orf62 View Gene Set 0.000906 29 0.0357 88 Protein-protein-interaction for C19orf62 www.ncbi.nlm.ni...
Null ppi.STAT3 View Gene Set 0.0009065 93 0.0357 88 Protein-protein-interaction for STAT3 www.ncbi.nlm.ni...
Null ppi.XBP1 View Gene Set 0.0009078 11 0.0357 88 Protein-protein-interaction for XBP1 www.ncbi.nlm.ni...
Null ppi.MED10 View Gene Set 0.0008909 46 0.0357 88 Protein-protein-interaction for MED10 www.ncbi.nlm.ni...
Null ppi.NCOA1 View Gene Set 0.0009287 56 0.0357 88 Protein-protein-interaction for NCOA1 www.ncbi.nlm.ni...
Null ppi.YWHAQ View Gene Set 0.0009499 104 0.03582 95 Protein-protein-interaction for YWHAQ www.ncbi.nlm.ni...
Null ppi.JUNB View Gene Set 0.0009568 11 0.03582 95 Protein-protein-interaction for JUNB www.ncbi.nlm.ni...
Null ppi.TBPL1 View Gene Set 0.001003 13 0.03715 97 Protein-protein-interaction for TBPL1 www.ncbi.nlm.ni...
Null ppi.GPSM1 View Gene Set 0.001049 5 0.03734 98 Protein-protein-interaction for GPSM1 www.ncbi.nlm.ni...
Null ppi.WDR48 View Gene Set 0.001047 52 0.03734 98 Protein-protein-interaction for WDR48 www.ncbi.nlm.ni...
Null ppi.ZEB1 View Gene Set 0.001045 8 0.03734 98 Protein-protein-interaction for ZEB1 www.ncbi.nlm.ni...
Null ppi.SPAG9 View Gene Set 0.001047 11 0.03734 98 Protein-protein-interaction for SPAG9 www.ncbi.nlm.ni...
Null ppi.PML View Gene Set 0.001086 36 0.03755 102 Protein-protein-interaction for PML www.ncbi.nlm.ni...
Null ppi.TAF10 View Gene Set 0.001078 29 0.03755 102 Protein-protein-interaction for TAF10 www.ncbi.nlm.ni...
Null ppi.TAF1D View Gene Set 0.001087 21 0.03755 102 Protein-protein-interaction for TAF1D www.ncbi.nlm.ni...
Null ppi.MED29 View Gene Set 0.001102 38 0.03761 105 Protein-protein-interaction for MED29 www.ncbi.nlm.ni...
Null ppi.TAF9 View Gene Set 0.001109 24 0.03761 105 Protein-protein-interaction for TAF9 www.ncbi.nlm.ni...
Null ppi.CNOT8 View Gene Set 0.00115 7 0.03862 107 Protein-protein-interaction for CNOT8 www.ncbi.nlm.ni...
Null ppi.YWHAB View Gene Set 0.001207 81 0.03987 108 Protein-protein-interaction for YWHAB www.ncbi.nlm.ni...
Null ppi.MAP1LC3B View Gene Set 0.001209 26 0.03987 108 Protein-protein-interaction for MAP1LC3B www.ncbi.nlm.ni...
Null ppi.THRA View Gene Set 0.00124 29 0.04015 110 Protein-protein-interaction for THRA www.ncbi.nlm.ni...
Null ppi.KEAP1 View Gene Set 0.00123 22 0.04015 110 Protein-protein-interaction for KEAP1 www.ncbi.nlm.ni...
Null ppi.PSMC2 View Gene Set 0.001284 6 0.04121 112 Protein-protein-interaction for PSMC2 www.ncbi.nlm.ni...
Null ppi.PIAS2 View Gene Set 0.001305 36 0.04151 113 Protein-protein-interaction for PIAS2 www.ncbi.nlm.ni...
Null ppi.MED15 View Gene Set 0.001363 17 0.04297 114 Protein-protein-interaction for MED15 www.ncbi.nlm.ni...
Null ppi.UBB View Gene Set 0.001388 46 0.04301 115 Protein-protein-interaction for UBB www.ncbi.nlm.ni...
Null ppi.XRCC1 View Gene Set 0.001384 11 0.04301 115 Protein-protein-interaction for XRCC1 www.ncbi.nlm.ni...
Null ppi.C13orf34 View Gene Set 0.001409 8 0.04328 117 Protein-protein-interaction for C13orf34 www.ncbi.nlm.ni...
Null ppi.SRPK2 View Gene Set 0.001439 7 0.04383 118 Protein-protein-interaction for SRPK2 www.ncbi.nlm.ni...
Null ppi.CUX1 View Gene Set 0.001463 8 0.04389 119 Protein-protein-interaction for CUX1 www.ncbi.nlm.ni...
Null ppi.TP53BP1 View Gene Set 0.001466 17 0.04389 119 Protein-protein-interaction for TP53BP1 www.ncbi.nlm.ni...
Null ppi.1460853 View Gene Set 0.001496 6 0.04443 121 Protein-protein-interaction for 1460853 www.ncbi.nlm.ni...
Null ppi.CDK2 View Gene Set 0.001593 15 0.04456 122 Protein-protein-interaction for CDK2 www.ncbi.nlm.ni...
Null ppi.BRD4 View Gene Set 0.001648 19 0.04456 122 Protein-protein-interaction for BRD4 www.ncbi.nlm.ni...
Null ppi.XRN1 View Gene Set 0.001639 25 0.04456 122 Protein-protein-interaction for XRN1 www.ncbi.nlm.ni...
Null ppi.CLSPN View Gene Set 0.001536 18 0.04456 122 Protein-protein-interaction for CLSPN www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 0.001599 43 0.04456 122 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.TRRAP View Gene Set 0.001621 21 0.04456 122 Protein-protein-interaction for TRRAP www.ncbi.nlm.ni...
Null ppi.PRAM1 View Gene Set 0.001564 11 0.04456 122 Protein-protein-interaction for PRAM1 www.ncbi.nlm.ni...
Null ppi.NR0B2 View Gene Set 0.001646 31 0.04456 122 Protein-protein-interaction for NR0B2 www.ncbi.nlm.ni...
Null ppi.TIMELESS View Gene Set 0.001644 8 0.04456 122 Protein-protein-interaction for TIMELESS www.ncbi.nlm.ni...
Null ppi.BCAR1 View Gene Set 0.00153 46 0.04456 122 Protein-protein-interaction for BCAR1 www.ncbi.nlm.ni...
Null ppi.NCOR2 View Gene Set 0.001634 74 0.04456 122 Protein-protein-interaction for NCOR2 www.ncbi.nlm.ni...
Null ppi.MED13 View Gene Set 0.001649 12 0.04456 122 Protein-protein-interaction for MED13 www.ncbi.nlm.ni...
Null ppi.ARIH1 View Gene Set 0.001674 7 0.04491 134 Protein-protein-interaction for ARIH1 www.ncbi.nlm.ni...
Null ppi.CTCF View Gene Set 0.001722 11 0.04517 135 Protein-protein-interaction for CTCF www.ncbi.nlm.ni...
Null ppi.CSNK2B View Gene Set 0.001713 17 0.04517 135 Protein-protein-interaction for CSNK2B www.ncbi.nlm.ni...
Null ppi.FZR1 View Gene Set 0.001734 15 0.04517 135 Protein-protein-interaction for FZR1 www.ncbi.nlm.ni...
Null ppi.SPI1 View Gene Set 0.001726 35 0.04517 135 Protein-protein-interaction for SPI1 www.ncbi.nlm.ni...
Null ppi.WWOX View Gene Set 0.001766 26 0.04532 139 Protein-protein-interaction for WWOX www.ncbi.nlm.ni...
Null ppi.ZBTB16 View Gene Set 0.001759 50 0.04532 139 Protein-protein-interaction for ZBTB16 www.ncbi.nlm.ni...
Null ppi.SRCAP View Gene Set 0.001781 7 0.0454 141 Protein-protein-interaction for SRCAP www.ncbi.nlm.ni...
Null ppi.CDKN1A View Gene Set 0.001844 20 0.0455 142 Protein-protein-interaction for CDKN1A www.ncbi.nlm.ni...
Null ppi.ORC4L View Gene Set 0.001868 10 0.0455 142 Protein-protein-interaction for ORC4L www.ncbi.nlm.ni...
Null ppi.POLR2A View Gene Set 0.001846 49 0.0455 142 Protein-protein-interaction for POLR2A www.ncbi.nlm.ni...
Null ppi.CHFR View Gene Set 0.001831 22 0.0455 142 Protein-protein-interaction for CHFR www.ncbi.nlm.ni...
Null ppi.ANAPC1 View Gene Set 0.001874 15 0.0455 142 Protein-protein-interaction for ANAPC1 www.ncbi.nlm.ni...
Null ppi.NRIP1 View Gene Set 0.001866 39 0.0455 142 Protein-protein-interaction for NRIP1 www.ncbi.nlm.ni...
Null ppi.SMC3 View Gene Set 0.001866 17 0.0455 142 Protein-protein-interaction for SMC3 www.ncbi.nlm.ni...
Null ppi.COPS8 View Gene Set 0.001916 13 0.04622 149 Protein-protein-interaction for COPS8 www.ncbi.nlm.ni...
Null ppi.CBLC View Gene Set 0.00203 13 0.04651 150 Protein-protein-interaction for CBLC www.ncbi.nlm.ni...
Null ppi.PACSIN1 View Gene Set 0.002013 27 0.04651 150 Protein-protein-interaction for PACSIN1 www.ncbi.nlm.ni...
Null ppi.MAX View Gene Set 0.002039 16 0.04651 150 Protein-protein-interaction for MAX www.ncbi.nlm.ni...
Null ppi.NUP98 View Gene Set 0.002038 12 0.04651 150 Protein-protein-interaction for NUP98 www.ncbi.nlm.ni...
Null ppi.PBRM1 View Gene Set 0.002017 7 0.04651 150 Protein-protein-interaction for PBRM1 www.ncbi.nlm.ni...
Null ppi.RAD23A View Gene Set 0.002046 9 0.04651 150 Protein-protein-interaction for RAD23A www.ncbi.nlm.ni...
Null ppi.RAN View Gene Set 0.001982 15 0.04651 150 Protein-protein-interaction for RAN www.ncbi.nlm.ni...
Null ppi.SMARCC1 View Gene Set 0.001979 27 0.04651 150 Protein-protein-interaction for SMARCC1 www.ncbi.nlm.ni...
Null ppi.TDG View Gene Set 0.002 17 0.04651 150 Protein-protein-interaction for TDG www.ncbi.nlm.ni...
Null ppi.TRIM24 View Gene Set 0.002058 25 0.04651 150 Protein-protein-interaction for TRIM24 www.ncbi.nlm.ni...
Null ppi.RFWD2 View Gene Set 0.002087 26 0.04687 160 Protein-protein-interaction for RFWD2 www.ncbi.nlm.ni...
Null ppi.MAPK9 View Gene Set 0.0021 21 0.04688 161 Protein-protein-interaction for MAPK9 www.ncbi.nlm.ni...
Null ppi.FOSL1 View Gene Set 0.002123 12 0.0471 162 Protein-protein-interaction for FOSL1 www.ncbi.nlm.ni...
Null ppi.PIAS1 View Gene Set 0.00225 52 0.04961 163 Protein-protein-interaction for PIAS1 www.ncbi.nlm.ni...

Gene Set Collection: pathwayCommons.cell-map

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null TGFBR View Gene Set 1.055e-10 124 1.055e-09 1 CELL_MAP - TGFBR gene set www.pathwaycomm...
Null AndrogenReceptor View Gene Set 3.064e-08 78 1.532e-07 2 CELL_MAP - AndrogenReceptor gene set www.pathwaycomm...
Null TNF alpha/NF-kB View Gene Set 0.0008922 170 0.002974 3 CELL_MAP - TNF alpha/NF-kB gene set www.pathwaycomm...
Null Wnt View Gene Set 0.00264 81 0.0066 4 CELL_MAP - Wnt gene set www.pathwaycomm...
Null ID View Gene Set 0.01025 14 0.01708 5 CELL_MAP - ID gene set www.pathwaycomm...
Null NOTCH View Gene Set 0.009668 58 0.01708 5 CELL_MAP - NOTCH gene set www.pathwaycomm...
Null EGFR1 View Gene Set 0.02903 137 0.04147 7 CELL_MAP - EGFR1 gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.humancyc

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null superpathway of cholesterol biosynthesis View Gene Set 2.138e-05 25 0.00556 1 HUMANCYC - superpathway of cholesterol biosynthesis gene set www.pathwaycomm...
Null cholesterol biosynthesis II (via 24 25-dihydrolanosterol) View Gene Set 8.928e-05 13 0.005803 2 HUMANCYC - cholesterol biosynthesis II (via 24 25-dihydrolanosterol) gene set www.pathwaycomm... 25-dihydrolanos...
Null cholesterol biosynthesis I View Gene Set 8.928e-05 13 0.005803 2 HUMANCYC - cholesterol biosynthesis I gene set www.pathwaycomm...
Null cholesterol biosynthesis III (via desmosterol) View Gene Set 8.928e-05 13 0.005803 2 HUMANCYC - cholesterol biosynthesis III (via desmosterol) gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.nci-nature

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Glypican pathway View Gene Set 4.571e-14 937 8.501e-12 1 NCI_NATURE - Glypican pathway gene set www.pathwaycomm...
Null Glypican 1 network View Gene Set 4.228e-11 796 3.624e-09 2 NCI_NATURE - Glypican 1 network gene set www.pathwaycomm...
Null Proteogylcan syndecan-mediated signaling events View Gene Set 5.846e-11 875 3.624e-09 2 NCI_NATURE - Proteogylcan syndecan-mediated signaling events gene set www.pathwaycomm...
Null ErbB1 downstream signaling View Gene Set 1.742e-09 812 5.399e-08 4 NCI_NATURE - ErbB1 downstream signaling gene set www.pathwaycomm...
Null EGF receptor (ErbB1) signaling pathway View Gene Set 1.742e-09 812 5.399e-08 4 NCI_NATURE - EGF receptor (ErbB1) signaling pathway gene set www.pathwaycomm...
Null Internalization of ErbB1 View Gene Set 1.742e-09 812 5.399e-08 4 NCI_NATURE - Internalization of ErbB1 gene set www.pathwaycomm...
Null IFN-gamma pathway View Gene Set 6.46e-09 590 1.502e-07 7 NCI_NATURE - IFN-gamma pathway gene set www.pathwaycomm...
Null ErbB receptor signaling network View Gene Set 6.31e-09 841 1.502e-07 7 NCI_NATURE - ErbB receptor signaling network gene set www.pathwaycomm...
Null Regulation of Androgen receptor activity View Gene Set 7.722e-09 108 1.596e-07 9 NCI_NATURE - Regulation of Androgen receptor activity gene set www.pathwaycomm...
Null Class I PI3K signaling events mediated by Akt View Gene Set 6.772e-08 532 1.26e-06 10 NCI_NATURE - Class I PI3K signaling events mediated by Akt gene set www.pathwaycomm...
Null TRAIL signaling pathway View Gene Set 1.027e-07 686 1.736e-06 11 NCI_NATURE - TRAIL signaling pathway gene set www.pathwaycomm...
Null Androgen-mediated signaling View Gene Set 1.85e-07 130 2.418e-06 12 NCI_NATURE - Androgen-mediated signaling gene set www.pathwaycomm...
Null Regulation of Wnt-mediated beta catenin signaling and target gene transcription View Gene Set 1.908e-07 135 2.418e-06 12 NCI_NATURE - Regulation of Wnt-mediated beta catenin signaling and target gene transcription gene set www.pathwaycomm...
Null Canonical Wnt signaling pathway View Gene Set 2.08e-07 156 2.418e-06 12 NCI_NATURE - Canonical Wnt signaling pathway gene set www.pathwaycomm...
Null Syndecan-4-mediated signaling events View Gene Set 1.796e-07 212 2.418e-06 12 NCI_NATURE - Syndecan-4-mediated signaling events gene set www.pathwaycomm...
Null Noncanonical Wnt signaling pathway View Gene Set 1.952e-07 185 2.418e-06 12 NCI_NATURE - Noncanonical Wnt signaling pathway gene set www.pathwaycomm...
Null TGF-beta receptor signaling View Gene Set 2.635e-07 306 2.579e-06 17 NCI_NATURE - TGF-beta receptor signaling gene set www.pathwaycomm...
Null Regulation of nuclear SMAD2/3 signaling View Gene Set 2.635e-07 306 2.579e-06 17 NCI_NATURE - Regulation of nuclear SMAD2/3 signaling gene set www.pathwaycomm...
Null Regulation of cytoplasmic and nuclear SMAD2/3 signaling View Gene Set 2.635e-07 306 2.579e-06 17 NCI_NATURE - Regulation of cytoplasmic and nuclear SMAD2/3 signaling gene set www.pathwaycomm...
Null Coregulation of Androgen receptor activity View Gene Set 5.535e-07 61 5.148e-06 20 NCI_NATURE - Coregulation of Androgen receptor activity gene set www.pathwaycomm...
Null Polo-like kinase signaling events in the cell cycle View Gene Set 6.379e-07 109 5.65e-06 21 NCI_NATURE - Polo-like kinase signaling events in the cell cycle gene set www.pathwaycomm...
Null ALK1 pathway View Gene Set 1.101e-06 324 8.659e-06 22 NCI_NATURE - ALK1 pathway gene set www.pathwaycomm...
Null p53 pathway View Gene Set 1.117e-06 190 8.659e-06 22 NCI_NATURE - p53 pathway gene set www.pathwaycomm...
Null ALK1 signaling events View Gene Set 1.106e-06 322 8.659e-06 22 NCI_NATURE - ALK1 signaling events gene set www.pathwaycomm...
Null Wnt signaling network View Gene Set 2.089e-06 203 1.554e-05 25 NCI_NATURE - Wnt signaling network gene set www.pathwaycomm...
Null Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) View Gene Set 2.288e-06 677 1.636e-05 26 NCI_NATURE - Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) gene set www.pathwaycomm...
Null Class I PI3K signaling events View Gene Set 2.398e-06 632 1.652e-05 27 NCI_NATURE - Class I PI3K signaling events gene set www.pathwaycomm...
Null Syndecan-1-mediated signaling events View Gene Set 3.086e-06 688 2.05e-05 28 NCI_NATURE - Syndecan-1-mediated signaling events gene set www.pathwaycomm...
Null TNF receptor signaling pathway View Gene Set 3.385e-06 299 2.104e-05 29 NCI_NATURE - TNF receptor signaling pathway gene set www.pathwaycomm...
Null Glypican 3 network View Gene Set 3.394e-06 209 2.104e-05 29 NCI_NATURE - Glypican 3 network gene set www.pathwaycomm...
Null PLK1 signaling events View Gene Set 3.628e-06 104 2.177e-05 31 NCI_NATURE - PLK1 signaling events gene set www.pathwaycomm...
Null Signaling events mediated by focal adhesion kinase View Gene Set 6.598e-06 660 3.835e-05 32 NCI_NATURE - Signaling events mediated by focal adhesion kinase gene set www.pathwaycomm...
Null Signaling by Aurora kinases View Gene Set 7.099e-06 98 4.001e-05 33 NCI_NATURE - Signaling by Aurora kinases gene set www.pathwaycomm...
Null Direct p53 effectors View Gene Set 2.466e-05 139 0.0001349 34 NCI_NATURE - Direct p53 effectors gene set www.pathwaycomm...
Null Regulation of retinoblastoma protein View Gene Set 2.639e-05 66 0.0001402 35 NCI_NATURE - Regulation of retinoblastoma protein gene set www.pathwaycomm...
Null LKB1 signaling events View Gene Set 2.931e-05 372 0.0001514 36 NCI_NATURE - LKB1 signaling events gene set www.pathwaycomm...
Null C-MYC pathway View Gene Set 6.256e-05 149 0.0003145 37 NCI_NATURE - C-MYC pathway gene set www.pathwaycomm...
Null E2F transcription factor network View Gene Set 8.136e-05 73 0.0003982 38 NCI_NATURE - E2F transcription factor network gene set www.pathwaycomm...
Null FAS (CD95) signaling pathway View Gene Set 9.743e-05 130 0.0004647 39 NCI_NATURE - FAS (CD95) signaling pathway gene set www.pathwaycomm...
Null Aurora B signaling View Gene Set 0.0001079 41 0.0005019 40 NCI_NATURE - Aurora B signaling gene set www.pathwaycomm...
Null EGFR-dependent Endothelin signaling events View Gene Set 0.0001141 345 0.0005178 41 NCI_NATURE - EGFR-dependent Endothelin signaling events gene set www.pathwaycomm...
Null mTOR signaling pathway View Gene Set 0.0001371 343 0.000607 42 NCI_NATURE - mTOR signaling pathway gene set www.pathwaycomm...
Null Aurora A signaling View Gene Set 0.000246 64 0.001064 43 NCI_NATURE - Aurora A signaling gene set www.pathwaycomm...
Null Retinoic acid receptors-mediated signaling View Gene Set 0.0002742 47 0.001159 44 NCI_NATURE - Retinoic acid receptors-mediated signaling gene set www.pathwaycomm...
Null Regulation of CDC42 activity View Gene Set 0.0002902 231 0.001199 45 NCI_NATURE - Regulation of CDC42 activity gene set www.pathwaycomm...
Null IL1-mediated signaling events View Gene Set 0.0003065 234 0.001239 46 NCI_NATURE - IL1-mediated signaling events gene set www.pathwaycomm...
Null BMP receptor signaling View Gene Set 0.0003301 226 0.001306 47 NCI_NATURE - BMP receptor signaling gene set www.pathwaycomm...
Null Regulation of Telomerase View Gene Set 0.0004637 68 0.001797 48 NCI_NATURE - Regulation of Telomerase gene set www.pathwaycomm...
Null Validated targets of C-MYC transcriptional activation View Gene Set 0.0005061 80 0.001921 49 NCI_NATURE - Validated targets of C-MYC transcriptional activation gene set www.pathwaycomm...
Null Signaling events mediated by HDAC Class I View Gene Set 0.0008815 114 0.003279 50 NCI_NATURE - Signaling events mediated by HDAC Class I gene set www.pathwaycomm...
Null FOXM1 transcription factor network View Gene Set 0.001083 42 0.003949 51 NCI_NATURE - FOXM1 transcription factor network gene set www.pathwaycomm...
Null EphrinB-EPHB pathway View Gene Set 0.001336 57 0.004779 52 NCI_NATURE - EphrinB-EPHB pathway gene set www.pathwaycomm...
Null p38 MAPK signaling pathway View Gene Set 0.001861 189 0.006531 53 NCI_NATURE - p38 MAPK signaling pathway gene set www.pathwaycomm...
Null Nectin adhesion pathway View Gene Set 0.001917 126 0.006602 54 NCI_NATURE - Nectin adhesion pathway gene set www.pathwaycomm...
Null Sumoylation by RanBP2 regulates transcriptional repression View Gene Set 0.002076 15 0.00702 55 NCI_NATURE - Sumoylation by RanBP2 regulates transcriptional repression gene set www.pathwaycomm...
Null p75(NTR)-mediated signaling View Gene Set 0.002154 180 0.007153 56 NCI_NATURE - p75(NTR)-mediated signaling gene set www.pathwaycomm...
Null Ephrin B reverse signaling View Gene Set 0.002278 28 0.007433 57 NCI_NATURE - Ephrin B reverse signaling gene set www.pathwaycomm...
Null CDC42 signaling events View Gene Set 0.002689 219 0.008625 58 NCI_NATURE - CDC42 signaling events gene set www.pathwaycomm...
Null Signaling events mediated by HDAC Class II View Gene Set 0.002952 38 0.009305 59 NCI_NATURE - Signaling events mediated by HDAC Class II gene set www.pathwaycomm...
Null Sphingosine 1-phosphate (S1P) pathway View Gene Set 0.003048 138 0.009448 60 NCI_NATURE - Sphingosine 1-phosphate (S1P) pathway gene set www.pathwaycomm...
Null Endothelins View Gene Set 0.003244 439 0.009833 61 NCI_NATURE - Endothelins gene set www.pathwaycomm...
Null Syndecan-2-mediated signaling events View Gene Set 0.003278 77 0.009833 61 NCI_NATURE - Syndecan-2-mediated signaling events gene set www.pathwaycomm...
Null FoxO family signaling View Gene Set 0.004168 49 0.01231 63 NCI_NATURE - FoxO family signaling gene set www.pathwaycomm...
Null Validated targets of C-MYC transcriptional repression View Gene Set 0.00467 64 0.01336 64 NCI_NATURE - Validated targets of C-MYC transcriptional repression gene set www.pathwaycomm...
Null IL2-mediated signaling events View Gene Set 0.004613 116 0.01336 64 NCI_NATURE - IL2-mediated signaling events gene set www.pathwaycomm...
Null HIV-1 Nef: Negative effector of Fas and TNF-alpha View Gene Set 0.005293 35 0.01492 66 NCI_NATURE - HIV-1 Nef: Negative effector of Fas and TNF-alpha gene set www.pathwaycomm...
Null Hedgehog signaling events mediated by Gli proteins View Gene Set 0.00632 48 0.01755 67 NCI_NATURE - Hedgehog signaling events mediated by Gli proteins gene set www.pathwaycomm...
Null Circadian rhythm pathway View Gene Set 0.006692 14 0.01831 68 NCI_NATURE - Circadian rhythm pathway gene set www.pathwaycomm...
Null RAC1 signaling pathway View Gene Set 0.007167 194 0.01852 69 NCI_NATURE - RAC1 signaling pathway gene set www.pathwaycomm...
Null Regulation of RAC1 activity View Gene Set 0.007167 194 0.01852 69 NCI_NATURE - Regulation of RAC1 activity gene set www.pathwaycomm...
Null Regulation of RhoA activity View Gene Set 0.007167 194 0.01852 69 NCI_NATURE - Regulation of RhoA activity gene set www.pathwaycomm...
Null RhoA signaling pathway View Gene Set 0.007167 194 0.01852 69 NCI_NATURE - RhoA signaling pathway gene set www.pathwaycomm...
Null Regulation of p38-alpha and p38-beta View Gene Set 0.00884 164 0.02252 73 NCI_NATURE - Regulation of p38-alpha and p38-beta gene set www.pathwaycomm...
Null FGF signaling pathway View Gene Set 0.009677 48 0.02432 74 NCI_NATURE - FGF signaling pathway gene set www.pathwaycomm...
Null Ceramide signaling pathway View Gene Set 0.00982 49 0.02435 75 NCI_NATURE - Ceramide signaling pathway gene set www.pathwaycomm...
Null PDGFR-beta signaling pathway View Gene Set 0.01038 55 0.02541 76 NCI_NATURE - PDGFR-beta signaling pathway gene set www.pathwaycomm...
Null PLK2 and PLK4 events View Gene Set 0.01145 2 0.0273 77 NCI_NATURE - PLK2 and PLK4 events gene set www.pathwaycomm...
Null S1P1 pathway View Gene Set 0.01138 71 0.0273 77 NCI_NATURE - S1P1 pathway gene set www.pathwaycomm...
Null Signaling mediated by p38-alpha and p38-beta View Gene Set 0.01465 50 0.0345 79 NCI_NATURE - Signaling mediated by p38-alpha and p38-beta gene set www.pathwaycomm...
Null IL6-mediated signaling events View Gene Set 0.01677 48 0.03899 80 NCI_NATURE - IL6-mediated signaling events gene set www.pathwaycomm...
Null IL2 signaling events mediated by PI3K View Gene Set 0.01736 68 0.03987 81 NCI_NATURE - IL2 signaling events mediated by PI3K gene set www.pathwaycomm...
Null Signaling events mediated by the Hedgehog family View Gene Set 0.01804 65 0.04091 82 NCI_NATURE - Signaling events mediated by the Hedgehog family gene set www.pathwaycomm...
Null C-MYB transcription factor network View Gene Set 0.01866 85 0.04181 83 NCI_NATURE - C-MYB transcription factor network gene set www.pathwaycomm...
Null RXR and RAR heterodimerization with other nuclear receptor View Gene Set 0.02062 26 0.04565 84 NCI_NATURE - RXR and RAR heterodimerization with other nuclear receptor gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.reactome

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Cell Cycle Mitotic View Gene Set 7.844e-17 312 8.762e-14 1 REACTOME - Cell Cycle Mitotic gene set www.pathwaycomm... Mitotic&format=...
Null mRNA Processing View Gene Set 5.015e-13 158 1.867e-10 2 REACTOME - mRNA Processing gene set www.pathwaycomm...
Null Processing of Capped Intron-Containing Pre-mRNA View Gene Set 3.516e-13 138 1.867e-10 2 REACTOME - Processing of Capped Intron-Containing Pre-mRNA gene set www.pathwaycomm...
Null Formation and Maturation of mRNA Transcript View Gene Set 1.636e-12 185 4.569e-10 4 REACTOME - Formation and Maturation of mRNA Transcript gene set www.pathwaycomm...
Null DNA Replication View Gene Set 1.977e-11 200 4.417e-09 5 REACTOME - DNA Replication gene set www.pathwaycomm...
Null Metabolism of RNA View Gene Set 3.783e-10 174 7.044e-08 6 REACTOME - Metabolism of RNA gene set www.pathwaycomm...
Null Mitotic M-M/G1 phases View Gene Set 5.029e-10 180 8.025e-08 7 REACTOME - Mitotic M-M/G1 phases gene set www.pathwaycomm...
Null mRNA Splicing - Major Pathway View Gene Set 6.212e-09 107 7.455e-07 8 REACTOME - mRNA Splicing - Major Pathway gene set www.pathwaycomm...
Null mRNA Splicing View Gene Set 6.212e-09 107 7.455e-07 8 REACTOME - mRNA Splicing gene set www.pathwaycomm...
Null Transport of Mature Transcript to Cytoplasm View Gene Set 6.706e-09 55 7.455e-07 8 REACTOME - Transport of Mature Transcript to Cytoplasm gene set www.pathwaycomm...
Null Mitotic G2-G2/M phases View Gene Set 7.342e-09 98 7.455e-07 8 REACTOME - Mitotic G2-G2/M phases gene set www.pathwaycomm...
Null Transport of Mature mRNA derived from an Intron-Containing Transcript View Gene Set 1.057e-08 51 9.836e-07 12 REACTOME - Transport of Mature mRNA derived from an Intron-Containing Transcript gene set www.pathwaycomm...
Null G2/M Transition View Gene Set 1.244e-08 96 1.069e-06 13 REACTOME - G2/M Transition gene set www.pathwaycomm...
Null M Phase View Gene Set 2.218e-08 90 1.77e-06 14 REACTOME - M Phase gene set www.pathwaycomm...
Null Mitotic Prometaphase View Gene Set 5.963e-08 86 4.441e-06 15 REACTOME - Mitotic Prometaphase gene set www.pathwaycomm...
Null Cell Cycle Checkpoints View Gene Set 1.266e-07 124 8.838e-06 16 REACTOME - Cell Cycle Checkpoints gene set www.pathwaycomm...
Null Phosphorylation of the APC/C View Gene Set 2.819e-07 26 1.852e-05 17 REACTOME - Phosphorylation of the APC/C gene set www.pathwaycomm...
Null Regulation of mitotic cell cycle View Gene Set 4.999e-07 95 2.939e-05 18 REACTOME - Regulation of mitotic cell cycle gene set www.pathwaycomm...
Null APC/C-mediated degradation of cell cycle proteins View Gene Set 4.999e-07 95 2.939e-05 18 REACTOME - APC/C-mediated degradation of cell cycle proteins gene set www.pathwaycomm...
Null Metabolism of mRNA View Gene Set 1.201e-06 125 6.707e-05 20 REACTOME - Metabolism of mRNA gene set www.pathwaycomm...
Null G1/S Transition View Gene Set 2.126e-06 104 0.0001131 21 REACTOME - G1/S Transition gene set www.pathwaycomm...
Null S Phase View Gene Set 2.444e-06 113 0.0001241 22 REACTOME - S Phase gene set www.pathwaycomm...
Null Transport of the SLBP Dependant Mature mRNA View Gene Set 4.18e-06 33 0.0001776 23 REACTOME - Transport of the SLBP Dependant Mature mRNA gene set www.pathwaycomm...
Null Post-Elongation Processing of the Transcript View Gene Set 4.004e-06 43 0.0001776 23 REACTOME - Post-Elongation Processing of the Transcript gene set www.pathwaycomm...
Null Cleavage of Growing Transcript in the Termination Region View Gene Set 4.004e-06 43 0.0001776 23 REACTOME - Cleavage of Growing Transcript in the Termination Region gene set www.pathwaycomm...
Null RNA Polymerase II Transcription Termination View Gene Set 4.004e-06 43 0.0001776 23 REACTOME - RNA Polymerase II Transcription Termination gene set www.pathwaycomm...
Null Export of Viral Ribonucleoproteins from Nucleus View Gene Set 4.293e-06 31 0.0001776 23 REACTOME - Export of Viral Ribonucleoproteins from Nucleus gene set www.pathwaycomm...
Null Transport of Mature mRNAs Derived from Intronless Transcripts View Gene Set 5.586e-06 36 0.0002228 28 REACTOME - Transport of Mature mRNAs Derived from Intronless Transcripts gene set www.pathwaycomm...
Null Gene Expression View Gene Set 6.079e-06 381 0.0002289 29 REACTOME - Gene Expression gene set www.pathwaycomm...
Null Deadenylation-dependent mRNA decay View Gene Set 6.147e-06 46 0.0002289 29 REACTOME - Deadenylation-dependent mRNA decay gene set www.pathwaycomm...
Null Interactions of Rev with host cellular proteins View Gene Set 7.268e-06 33 0.000248 31 REACTOME - Interactions of Rev with host cellular proteins gene set www.pathwaycomm...
Null Cholesterol biosynthesis View Gene Set 7.253e-06 20 0.000248 31 REACTOME - Cholesterol biosynthesis gene set www.pathwaycomm...
Null Mitotic G1-G1/S phases View Gene Set 7.327e-06 113 0.000248 31 REACTOME - Mitotic G1-G1/S phases gene set www.pathwaycomm...
Null Transport of the SLBP independent Mature mRNA View Gene Set 8.896e-06 32 0.0002923 34 REACTOME - Transport of the SLBP independent Mature mRNA gene set www.pathwaycomm...
Null Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 9.694e-06 86 0.0003094 35 REACTOME - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null Nuclear import of Rev protein View Gene Set 1.073e-05 30 0.0003211 36 REACTOME - Nuclear import of Rev protein gene set www.pathwaycomm...
Null Transport of Ribonucleoproteins into the Host Nucleus View Gene Set 1.084e-05 29 0.0003211 36 REACTOME - Transport of Ribonucleoproteins into the Host Nucleus gene set www.pathwaycomm...
Null Regulation of APC/C activators between G1/S and early anaphase View Gene Set 1.092e-05 88 0.0003211 36 REACTOME - Regulation of APC/C activators between G1/S and early anaphase gene set www.pathwaycomm...
Null Transport of Mature mRNA Derived from an Intronless Transcript View Gene Set 1.174e-05 35 0.0003284 39 REACTOME - Transport of Mature mRNA Derived from an Intronless Transcript gene set www.pathwaycomm...
Null NEP/NS2 Interacts with the Cellular Export Machinery View Gene Set 1.176e-05 29 0.0003284 39 REACTOME - NEP/NS2 Interacts with the Cellular Export Machinery gene set www.pathwaycomm...
Null snRNP Assembly View Gene Set 1.375e-05 50 0.0003657 41 REACTOME - snRNP Assembly gene set www.pathwaycomm...
Null Metabolism of non-coding RNA View Gene Set 1.375e-05 50 0.0003657 41 REACTOME - Metabolism of non-coding RNA gene set www.pathwaycomm...
Null Post-Elongation Processing of Intron-Containing pre-mRNA View Gene Set 1.452e-05 34 0.0003685 43 REACTOME - Post-Elongation Processing of Intron-Containing pre-mRNA gene set www.pathwaycomm...
Null mRNA 3'-end processing View Gene Set 1.452e-05 34 0.0003685 43 REACTOME - mRNA 3'-end processing gene set www.pathwaycomm...
Null G2/M Checkpoints View Gene Set 1.563e-05 43 0.0003715 45 REACTOME - G2/M Checkpoints gene set www.pathwaycomm...
Null Cyclin A/B1 associated events during G2/M transition View Gene Set 1.551e-05 19 0.0003715 45 REACTOME - Cyclin A/B1 associated events during G2/M transition gene set www.pathwaycomm...
Null Transcriptional Regulation of White Adipocyte Differentiation View Gene Set 1.505e-05 69 0.0003715 45 REACTOME - Transcriptional Regulation of White Adipocyte Differentiation gene set www.pathwaycomm...
Null RNA Polymerase II Transcription View Gene Set 1.811e-05 101 0.0004214 48 REACTOME - RNA Polymerase II Transcription gene set www.pathwaycomm...
Null Rev-mediated nuclear export of HIV-1 RNA View Gene Set 2.079e-05 32 0.0004738 49 REACTOME - Rev-mediated nuclear export of HIV-1 RNA gene set www.pathwaycomm...
Null Transcription View Gene Set 2.557e-05 178 0.0005713 50 REACTOME - Transcription gene set www.pathwaycomm...
Null Deadenylation of mRNA View Gene Set 2.794e-05 22 0.000612 51 REACTOME - Deadenylation of mRNA gene set www.pathwaycomm...
Null Interactions of Vpr with host cellular proteins View Gene Set 3.033e-05 34 0.0006515 52 REACTOME - Interactions of Vpr with host cellular proteins gene set www.pathwaycomm...
Null Activation of ATR in response to replication stress View Gene Set 4.107e-05 37 0.0008656 53 REACTOME - Activation of ATR in response to replication stress gene set www.pathwaycomm...
Null Vpr-mediated nuclear import of PICs View Gene Set 4.415e-05 31 0.0009023 54 REACTOME - Vpr-mediated nuclear import of PICs gene set www.pathwaycomm...
Null Phosphorylation of Emi1 View Gene Set 4.443e-05 12 0.0009023 54 REACTOME - Phosphorylation of Emi1 gene set www.pathwaycomm...
Null Late Phase of HIV Life Cycle View Gene Set 4.779e-05 92 0.0009378 56 REACTOME - Late Phase of HIV Life Cycle gene set www.pathwaycomm...
Null Mitotic Metaphase/Anaphase Transition View Gene Set 4.785e-05 8 0.0009378 56 REACTOME - Mitotic Metaphase/Anaphase Transition gene set www.pathwaycomm...
Null Mitotic Telophase /Cytokinesis View Gene Set 6.636e-05 10 0.001278 58 REACTOME - Mitotic Telophase /Cytokinesis gene set www.pathwaycomm...
Null HIV Life Cycle View Gene Set 7.499e-05 103 0.00142 59 REACTOME - HIV Life Cycle gene set www.pathwaycomm...
Null Kinesins View Gene Set 0.0001041 22 0.001938 60 REACTOME - Kinesins gene set www.pathwaycomm...
Null Synthesis of DNA View Gene Set 0.0001088 102 0.001993 61 REACTOME - Synthesis of DNA gene set www.pathwaycomm...
Null Recruitment of mitotic centrosome proteins and complexes View Gene Set 0.0001332 72 0.002399 62 REACTOME - Recruitment of mitotic centrosome proteins and complexes gene set www.pathwaycomm...
Null HIV Infection View Gene Set 0.0001456 194 0.002581 63 REACTOME - HIV Infection gene set www.pathwaycomm...
Null Mitotic Spindle Checkpoint View Gene Set 0.0001582 19 0.002761 64 REACTOME - Mitotic Spindle Checkpoint gene set www.pathwaycomm...
Null Apoptosis View Gene Set 0.0001647 148 0.00283 65 REACTOME - Apoptosis gene set www.pathwaycomm...
Null Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components View Gene Set 0.0002014 18 0.003358 66 REACTOME - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components gene set www.pathwaycomm...
Null Inactivation of APC/C via direct inhibition of the APC/C complex View Gene Set 0.0002014 18 0.003358 66 REACTOME - Inactivation of APC/C via direct inhibition of the APC/C complex gene set www.pathwaycomm...
Null Regulation of Glucokinase by Glucokinase Regulatory Protein View Gene Set 0.0002308 29 0.003791 68 REACTOME - Regulation of Glucokinase by Glucokinase Regulatory Protein gene set www.pathwaycomm...
Null Polo-like kinase mediated events View Gene Set 0.0003037 10 0.004916 69 REACTOME - Polo-like kinase mediated events gene set www.pathwaycomm...
Null APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 View Gene Set 0.000314 77 0.005011 70 REACTOME - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 gene set www.pathwaycomm...
Null Centrosome maturation View Gene Set 0.0003209 73 0.005049 71 REACTOME - Centrosome maturation gene set www.pathwaycomm...
Null Activation of the pre-replicative complex View Gene Set 0.000402 30 0.006236 72 REACTOME - Activation of the pre-replicative complex gene set www.pathwaycomm...
Null DNA strand elongation View Gene Set 0.0004371 31 0.006688 73 REACTOME - DNA strand elongation gene set www.pathwaycomm...
Null Apoptotic execution phase View Gene Set 0.0004456 49 0.006727 74 REACTOME - Apoptotic execution phase gene set www.pathwaycomm...
Null G2/M DNA damage checkpoint View Gene Set 0.0004971 29 0.007403 75 REACTOME - G2/M DNA damage checkpoint gene set www.pathwaycomm...
Null Interleukin-1 signaling View Gene Set 0.0005147 38 0.007565 76 REACTOME - Interleukin-1 signaling gene set www.pathwaycomm...
Null Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase View Gene Set 0.0005379 16 0.007803 77 REACTOME - Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase gene set www.pathwaycomm...
Null mRNA Splicing - Minor Pathway View Gene Set 0.000606 42 0.008678 78 REACTOME - mRNA Splicing - Minor Pathway gene set www.pathwaycomm...
Null Activation of DNA fragmentation factor View Gene Set 0.0006521 8 0.008883 79 REACTOME - Activation of DNA fragmentation factor gene set www.pathwaycomm...
Null Apoptosis induced DNA fragmentation View Gene Set 0.0006521 8 0.008883 79 REACTOME - Apoptosis induced DNA fragmentation gene set www.pathwaycomm...
Null DNA Replication Pre-Initiation View Gene Set 0.0006435 90 0.008883 79 REACTOME - DNA Replication Pre-Initiation gene set www.pathwaycomm...
Null M/G1 Transition View Gene Set 0.0006435 90 0.008883 79 REACTOME - M/G1 Transition gene set www.pathwaycomm...
Null Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide LLO) and transfer to a nascent protein View Gene Set 0.0007996 30 0.01076 83 REACTOME - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide LLO) and transfer to a nascent protein gene set www.pathwaycomm... LLO) and transf...
Null APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 0.0008719 77 0.01146 84 REACTOME - APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null Removal of licensing factors from origins View Gene Set 0.0008705 78 0.01146 84 REACTOME - Removal of licensing factors from origins gene set www.pathwaycomm...
Null Unwinding of DNA View Gene Set 0.001034 11 0.01343 86 REACTOME - Unwinding of DNA gene set www.pathwaycomm...
Null Cyclin A:Cdk2-associated events at S phase entry View Gene Set 0.001116 62 0.01423 87 REACTOME - Cyclin A:Cdk2-associated events at S phase entry gene set www.pathwaycomm...
Null Regulation of DNA replication View Gene Set 0.001121 81 0.01423 87 REACTOME - Regulation of DNA replication gene set www.pathwaycomm...
Null E2F mediated regulation of DNA replication View Gene Set 0.001306 28 0.01639 89 REACTOME - E2F mediated regulation of DNA replication gene set www.pathwaycomm...
Null Switching of origins to a post-replicative state View Gene Set 0.001479 76 0.01816 90 REACTOME - Switching of origins to a post-replicative state gene set www.pathwaycomm...
Null Orc1 removal from chromatin View Gene Set 0.001479 76 0.01816 90 REACTOME - Orc1 removal from chromatin gene set www.pathwaycomm...
Null RNA Polymerase III Transcription View Gene Set 0.001735 34 0.02084 92 REACTOME - RNA Polymerase III Transcription gene set www.pathwaycomm...
Null RNA Polymerase III Abortive And Retractive Initiation View Gene Set 0.001735 34 0.02084 92 REACTOME - RNA Polymerase III Abortive And Retractive Initiation gene set www.pathwaycomm...
Null Regulation of mRNA Stability by Proteins that Bind AU-rich Elements View Gene Set 0.001754 95 0.02085 94 REACTOME - Regulation of mRNA Stability by Proteins that Bind AU-rich Elements gene set www.pathwaycomm...
Null Glucose transport View Gene Set 0.001996 38 0.02347 95 REACTOME - Glucose transport gene set www.pathwaycomm...
Null Cdc20:Phospho-APC/C mediated degradation of Cyclin A View Gene Set 0.002107 75 0.02451 96 REACTOME - Cdc20:Phospho-APC/C mediated degradation of Cyclin A gene set www.pathwaycomm...
Null Autodegradation of Cdh1 by Cdh1:APC/C View Gene Set 0.002178 67 0.02508 97 REACTOME - Autodegradation of Cdh1 by Cdh1:APC/C gene set www.pathwaycomm...
Null Host Interactions of HIV factors View Gene Set 0.002297 132 0.02618 98 REACTOME - Host Interactions of HIV factors gene set www.pathwaycomm...
Null RNA Polymerase III Transcription Initiation View Gene Set 0.002433 29 0.02745 99 REACTOME - RNA Polymerase III Transcription Initiation gene set www.pathwaycomm...
Null Generic Transcription Pathway View Gene Set 0.002519 35 0.02813 100 REACTOME - Generic Transcription Pathway gene set www.pathwaycomm...
Null Synthesis of substrates in N-glycan biosythesis View Gene Set 0.002705 16 0.02962 101 REACTOME - Synthesis of substrates in N-glycan biosythesis gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of Securin View Gene Set 0.002692 72 0.02962 101 REACTOME - APC/C:Cdc20 mediated degradation of Securin gene set www.pathwaycomm...
Null Cyclin E associated events during G1/S transition View Gene Set 0.003249 64 0.03524 103 REACTOME - Cyclin E associated events during G1/S transition gene set www.pathwaycomm...
Null Post-Elongation Processing of Intronless pre-mRNA View Gene Set 0.003336 23 0.03549 104 REACTOME - Post-Elongation Processing of Intronless pre-mRNA gene set www.pathwaycomm...
Null Processing of Capped Intronless Pre-mRNA View Gene Set 0.003336 23 0.03549 104 REACTOME - Processing of Capped Intronless Pre-mRNA gene set www.pathwaycomm...
Null Sphingolipid metabolism View Gene Set 0.003646 29 0.03842 106 REACTOME - Sphingolipid metabolism gene set www.pathwaycomm...
Null Pyrimidine biosynthesis View Gene Set 0.003683 6 0.03844 107 REACTOME - Pyrimidine biosynthesis gene set www.pathwaycomm...
Null Host Interactions with Influenza Factors View Gene Set 0.003832 5 0.03964 108 REACTOME - Host Interactions with Influenza Factors gene set www.pathwaycomm...
Null TRAIL signaling View Gene Set 0.003956 6 0.04054 109 REACTOME - TRAIL signaling gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of Cyclin B View Gene Set 0.004562 22 0.04633 110 REACTOME - APC/C:Cdc20 mediated degradation of Cyclin B gene set www.pathwaycomm...
Null Loss of proteins required for interphase microtubule organization from the centrosome View Gene Set 0.004836 62 0.04823 111 REACTOME - Loss of proteins required for interphase microtubule organization from the centrosome gene set www.pathwaycomm...
Null Loss of Nlp from mitotic centrosomes View Gene Set 0.004836 62 0.04823 111 REACTOME - Loss of Nlp from mitotic centrosomes gene set www.pathwaycomm...
Null Breakdown of the nuclear lamina View Gene Set 0.005071 3 0.04954 113 REACTOME - Breakdown of the nuclear lamina gene set www.pathwaycomm...
Null Assembly of the pre-replicative complex View Gene Set 0.005054 75 0.04954 113 REACTOME - Assembly of the pre-replicative complex gene set www.pathwaycomm...
Null APC-Cdc20 mediated degradation of Nek2A View Gene Set 0.0051 23 0.04954 113 REACTOME - APC-Cdc20 mediated degradation of Nek2A gene set www.pathwaycomm...

Gene Set Collection: miranda.targets

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-548c-3p View Gene Set 7.396e-42 3130 3.72e-39 1 microRNA targets for hsa-miR-548c-3p from miranda.targets www.mirbase.org...
Null hsa-miR-590-3p View Gene Set 1.099e-41 3575 3.72e-39 1 microRNA targets for hsa-miR-590-3p from miranda.targets www.mirbase.org...
Null hsa-miR-548n View Gene Set 1.73e-41 3830 3.903e-39 3 microRNA targets for hsa-miR-548n from miranda.targets www.mirbase.org...
Null hsa-miR-559 View Gene Set 1.833e-37 2900 3.103e-35 4 microRNA targets for hsa-miR-559 from miranda.targets www.mirbase.org...
Null hsa-miR-548g View Gene Set 3.579e-36 2114 4.847e-34 5 microRNA targets for hsa-miR-548g from miranda.targets www.mirbase.org...
Null hsa-miR-548a-3p View Gene Set 4.512e-34 2420 5.091e-32 6 microRNA targets for hsa-miR-548a-3p from miranda.targets www.mirbase.org...
Null hsa-miR-548d-3p View Gene Set 7.8e-34 2210 6.779e-32 7 microRNA targets for hsa-miR-548d-3p from miranda.targets www.mirbase.org...
Null hsa-miR-548p View Gene Set 8.011e-34 2743 6.779e-32 7 microRNA targets for hsa-miR-548p from miranda.targets www.mirbase.org...
Null hsa-miR-561 View Gene Set 1.587e-32 2925 1.194e-30 9 microRNA targets for hsa-miR-561 from miranda.targets www.mirbase.org...
Null hsa-miR-513a-3p View Gene Set 3.622e-32 2711 2.452e-30 10 microRNA targets for hsa-miR-513a-3p from miranda.targets www.mirbase.org...
Null hsa-miR-548f View Gene Set 1.221e-31 2082 7.512e-30 11 microRNA targets for hsa-miR-548f from miranda.targets www.mirbase.org...
Null hsa-miR-548e View Gene Set 5.206e-31 2325 2.937e-29 12 microRNA targets for hsa-miR-548e from miranda.targets www.mirbase.org...
Null hsa-miR-548a-5p View Gene Set 6.862e-31 2983 3.573e-29 13 microRNA targets for hsa-miR-548a-5p from miranda.targets www.mirbase.org...
Null hsa-miR-1283 View Gene Set 8.049e-31 1960 3.892e-29 14 microRNA targets for hsa-miR-1283 from miranda.targets www.mirbase.org...
Null hsa-miR-548i View Gene Set 1.14e-30 2860 4.824e-29 15 microRNA targets for hsa-miR-548i from miranda.targets www.mirbase.org...
Null hsa-miR-655 View Gene Set 1.09e-30 1858 4.824e-29 15 microRNA targets for hsa-miR-655 from miranda.targets www.mirbase.org...
Null hsa-miR-548l View Gene Set 1.478e-30 2599 5.885e-29 17 microRNA targets for hsa-miR-548l from miranda.targets www.mirbase.org...
Null hsa-miR-548d-5p View Gene Set 4.294e-30 3270 1.615e-28 18 microRNA targets for hsa-miR-548d-5p from miranda.targets www.mirbase.org...
Null hsa-miR-570 View Gene Set 6.08e-30 3124 2.166e-28 19 microRNA targets for hsa-miR-570 from miranda.targets www.mirbase.org...
Null hsa-miR-548o View Gene Set 1.451e-29 2216 4.91e-28 20 microRNA targets for hsa-miR-548o from miranda.targets www.mirbase.org...
Null hsa-miR-548b-5p View Gene Set 2.12e-28 3175 6.835e-27 21 microRNA targets for hsa-miR-548b-5p from miranda.targets www.mirbase.org...
Null hsa-miR-548j View Gene Set 2.319e-28 2652 7.137e-27 22 microRNA targets for hsa-miR-548j from miranda.targets www.mirbase.org...
Null hsa-miR-524-5p View Gene Set 1.309e-27 2574 3.854e-26 23 microRNA targets for hsa-miR-524-5p from miranda.targets www.mirbase.org...
Null hsa-miR-1252 View Gene Set 1.557e-27 3125 4.392e-26 24 microRNA targets for hsa-miR-1252 from miranda.targets www.mirbase.org...
Null hsa-miR-577 View Gene Set 1.737e-27 2745 4.705e-26 25 microRNA targets for hsa-miR-577 from miranda.targets www.mirbase.org...
Null hsa-miR-19a View Gene Set 2.516e-27 2189 6.55e-26 26 microRNA targets for hsa-miR-19a from miranda.targets www.mirbase.org...
Null hsa-miR-19b View Gene Set 5.747e-27 2017 1.441e-25 27 microRNA targets for hsa-miR-19b from miranda.targets www.mirbase.org...
Null hsa-miR-548c-5p View Gene Set 8.921e-27 2909 2.157e-25 28 microRNA targets for hsa-miR-548c-5p from miranda.targets www.mirbase.org...
Null hsa-miR-106a View Gene Set 9.585e-27 2173 2.163e-25 29 microRNA targets for hsa-miR-106a from miranda.targets www.mirbase.org...
Null hsa-miR-17 View Gene Set 9.585e-27 2173 2.163e-25 29 microRNA targets for hsa-miR-17 from miranda.targets www.mirbase.org...
Null hsa-miR-142-5p View Gene Set 1.114e-26 2312 2.432e-25 31 microRNA targets for hsa-miR-142-5p from miranda.targets www.mirbase.org...
Null hsa-miR-607 View Gene Set 1.326e-26 2322 2.805e-25 32 microRNA targets for hsa-miR-607 from miranda.targets www.mirbase.org...
Null hsa-miR-545 View Gene Set 1.43e-26 2246 2.933e-25 33 microRNA targets for hsa-miR-545 from miranda.targets www.mirbase.org...
Null hsa-miR-582-5p View Gene Set 1.517e-26 1971 3.02e-25 34 microRNA targets for hsa-miR-582-5p from miranda.targets www.mirbase.org...
Null hsa-miR-548h View Gene Set 4.513e-26 2539 8.73e-25 35 microRNA targets for hsa-miR-548h from miranda.targets www.mirbase.org...
Null hsa-miR-1323 View Gene Set 4.645e-26 2071 8.736e-25 36 microRNA targets for hsa-miR-1323 from miranda.targets www.mirbase.org...
Null hsa-miR-30c View Gene Set 1.298e-25 1792 2.376e-24 37 microRNA targets for hsa-miR-30c from miranda.targets www.mirbase.org...
Null hsa-miR-20b View Gene Set 2.236e-25 2122 3.984e-24 38 microRNA targets for hsa-miR-20b from miranda.targets www.mirbase.org...
Null hsa-miR-30a View Gene Set 3.418e-25 1611 5.933e-24 39 microRNA targets for hsa-miR-30a from miranda.targets www.mirbase.org...
Null hsa-miR-641 View Gene Set 5.098e-25 2384 8.629e-24 40 microRNA targets for hsa-miR-641 from miranda.targets www.mirbase.org...
Null hsa-miR-548k View Gene Set 5.23e-25 1874 8.636e-24 41 microRNA targets for hsa-miR-548k from miranda.targets www.mirbase.org...
Null hsa-miR-340 View Gene Set 5.533e-25 2504 8.919e-24 42 microRNA targets for hsa-miR-340 from miranda.targets www.mirbase.org...
Null hsa-miR-200b View Gene Set 7.365e-25 1789 1.16e-23 43 microRNA targets for hsa-miR-200b from miranda.targets www.mirbase.org...
Null hsa-miR-200c View Gene Set 1.598e-24 1794 2.459e-23 44 microRNA targets for hsa-miR-200c from miranda.targets www.mirbase.org...
Null hsa-miR-181c View Gene Set 1.897e-24 1844 2.854e-23 45 microRNA targets for hsa-miR-181c from miranda.targets www.mirbase.org...
Null hsa-miR-548m View Gene Set