Results

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Go to: Gene Set Collection: KEGG
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Go to: Gene Set Collection: Broad.c1.CYTOBAND
Go to: Gene Set Collection: Broad.c2.CGP
Go to: Gene Set Collection: Broad.c2.CP.BIOCARTA
Go to: Gene Set Collection: Broad.c2.CP.KEGG
Go to: Gene Set Collection: Broad.c2.CP.REACTOME
Go to: Gene Set Collection: Broad.c3.MIR
Go to: Gene Set Collection: Broad.c3.TFT
Go to: Gene Set Collection: Broad.c4.CGN
Go to: Gene Set Collection: Broad.c4.CM
Go to: Gene Set Collection: Broad.c5.BP
Go to: Gene Set Collection: Broad.c5.CC
Go to: Gene Set Collection: Broad.c5.MF
Go to: Gene Set Collection: PMID
Go to: Gene Set Collection: ChromosomalTiles5Mb
Go to: Gene Set Collection: Prosite
Go to: Gene Set Collection: Enzyme
Go to: Gene Set Collection: ppi.BIND
Go to: Gene Set Collection: ppi.BioGRID
Go to: Gene Set Collection: ppi.anyDB
Go to: Gene Set Collection: pathwayCommons.cell-map
Go to: Gene Set Collection: pathwayCommons.nci-nature
Go to: Gene Set Collection: pathwayCommons.reactome
Go to: Gene Set Collection: miranda.targets
Go to: Gene Set Collection: mirbase.targets
Go to: Gene Set Collection: targetscan.targets
Go to: Gene Set Collection: miRNAtargetUnion
Go to: Gene Set Collection: hprdBatch.UP
Go to: Gene Set Collection: hprdBatch.DIFFERENT

AFA results for: miR.1vsControl.ls

Click on the heading for any column to sort by that column.

Gene Set Collection: KEGG

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
KEGG 04141 View Gene Set 7.114e-13 167 1.522e-10 1 Protein processing in endoplasmic reticulum www.genome.jp/d...
KEGG 05012 View Gene Set 5.082e-07 132 5.438e-05 2 Parkinson's disease www.genome.jp/d...
KEGG 00190 View Gene Set 1.073e-06 134 5.885e-05 3 Oxidative phosphorylation www.genome.jp/d...
KEGG 00970 View Gene Set 1.375e-06 41 5.885e-05 3 Aminoacyl-tRNA biosynthesis www.genome.jp/d...
KEGG 04120 View Gene Set 1.37e-06 139 5.885e-05 3 Ubiquitin mediated proteolysis www.genome.jp/d...
KEGG 05016 View Gene Set 3.054e-06 184 0.0001089 6 Huntington's disease www.genome.jp/d...
KEGG 03050 View Gene Set 1.588e-05 48 0.0004853 7 Proteasome www.genome.jp/d...
KEGG 01100 View Gene Set 2.252e-05 1120 0.0006023 8 Metabolic pathways www.genome.jp/d...
KEGG 05010 View Gene Set 5.585e-05 168 0.001328 9 Alzheimer's disease www.genome.jp/d...
KEGG 04962 View Gene Set 0.0001513 44 0.003238 10 Vasopressin-regulated water reabsorption www.genome.jp/d...
KEGG 00020 View Gene Set 0.0005108 31 0.008565 11 Citrate cycle (TCA cycle) www.genome.jp/d...
KEGG 03060 View Gene Set 0.0005053 24 0.008565 11 Protein export www.genome.jp/d...
KEGG 04910 View Gene Set 0.0005203 137 0.008565 11 Insulin signaling pathway www.genome.jp/d...
KEGG 04664 View Gene Set 0.001102 79 0.01685 14 Fc epsilon RI signaling pathway www.genome.jp/d...
KEGG 03010 View Gene Set 0.002842 88 0.04055 15 Ribosome www.genome.jp/d...

Gene Set Collection: GO

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
GO GO:0005739 View Gene Set 2.552e-30 1274 3.409e-26 1 mitochondrion amigo.geneontol...
GO GO:0044444 View Gene Set 2.215e-23 5184 1.48e-19 2 cytoplasmic part amigo.geneontol...
GO GO:0005737 View Gene Set 4.281e-23 7676 1.907e-19 3 cytoplasm amigo.geneontol...
GO GO:0044429 View Gene Set 5.47e-21 619 1.827e-17 4 mitochondrial part amigo.geneontol...
GO GO:0044424 View Gene Set 7.144e-20 10976 1.909e-16 5 intracellular part amigo.geneontol...
GO GO:0006412 View Gene Set 2.1e-19 412 4.677e-16 6 translation amigo.geneontol...
GO GO:0005622 View Gene Set 1.747e-18 11329 3.334e-15 7 intracellular amigo.geneontol...
GO GO:0043231 View Gene Set 2.559e-18 8376 4.273e-15 8 intracellular membrane-bounded organelle amigo.geneontol...
GO GO:0043227 View Gene Set 3.328e-18 8383 4.941e-15 9 membrane-bounded organelle amigo.geneontol...
GO GO:0044422 View Gene Set 4.002e-18 5089 5.346e-15 10 organelle part amigo.geneontol...
GO GO:0044446 View Gene Set 7.963e-18 5019 9.671e-15 11 intracellular organelle part amigo.geneontol...
GO GO:0043229 View Gene Set 9.6e-17 9346 1.069e-13 12 intracellular organelle amigo.geneontol...
GO GO:0043226 View Gene Set 1.515e-16 9360 1.557e-13 13 organelle amigo.geneontol...
GO GO:0070013 View Gene Set 1.576e-15 1845 1.504e-12 14 intracellular organelle lumen amigo.geneontol...
GO GO:0044267 View Gene Set 2.797e-15 2465 2.491e-12 15 cellular protein metabolic process amigo.geneontol...
GO GO:0031974 View Gene Set 6.903e-15 1917 5.764e-12 16 membrane-enclosed lumen amigo.geneontol...
GO GO:0005740 View Gene Set 7.961e-15 444 6.256e-12 17 mitochondrial envelope amigo.geneontol...
GO GO:0031966 View Gene Set 2.672e-14 420 1.983e-11 18 mitochondrial membrane amigo.geneontol...
GO GO:0019538 View Gene Set 3.772e-14 2935 2.519e-11 19 protein metabolic process amigo.geneontol...
GO GO:0030529 View Gene Set 3.716e-14 504 2.519e-11 19 ribonucleoprotein complex amigo.geneontol...
GO GO:0005743 View Gene Set 7.782e-14 305 4.951e-11 21 mitochondrial inner membrane amigo.geneontol...
GO GO:0043233 View Gene Set 8.641e-14 1881 5.247e-11 22 organelle lumen amigo.geneontol...
GO GO:0034660 View Gene Set 1.015e-13 236 5.895e-11 23 ncRNA metabolic process amigo.geneontol...
GO GO:0032991 View Gene Set 1.985e-13 3237 1.105e-10 24 macromolecular complex amigo.geneontol...
GO GO:0019866 View Gene Set 1.006e-12 334 5.378e-10 25 organelle inner membrane amigo.geneontol...
GO GO:0005759 View Gene Set 6.749e-12 223 3.339e-09 26 mitochondrial matrix amigo.geneontol...
GO GO:0031980 View Gene Set 6.749e-12 223 3.339e-09 26 mitochondrial lumen amigo.geneontol...
GO GO:0044455 View Gene Set 2.312e-11 133 1.103e-08 28 mitochondrial membrane part amigo.geneontol...
GO GO:0031967 View Gene Set 2.787e-11 672 1.284e-08 29 organelle envelope amigo.geneontol...
GO GO:0044237 View Gene Set 1.716e-10 7431 7.642e-08 30 cellular metabolic process amigo.geneontol...
GO GO:0006457 View Gene Set 1.883e-10 172 7.862e-08 31 protein folding amigo.geneontol...
GO GO:0022613 View Gene Set 1.883e-10 194 7.862e-08 31 ribonucleoprotein complex biogenesis amigo.geneontol...
GO GO:0031975 View Gene Set 1.97e-10 685 7.975e-08 33 envelope amigo.geneontol...
GO GO:0005730 View Gene Set 2.776e-10 734 1.091e-07 34 nucleolus amigo.geneontol...
GO GO:0030163 View Gene Set 3.697e-10 398 1.411e-07 35 protein catabolic process amigo.geneontol...
GO GO:0042254 View Gene Set 4.533e-10 130 1.682e-07 36 ribosome biogenesis amigo.geneontol...
GO GO:0044257 View Gene Set 1.071e-09 349 3.869e-07 37 cellular protein catabolic process amigo.geneontol...
GO GO:0003723 View Gene Set 1.123e-09 732 3.95e-07 38 RNA binding amigo.geneontol...
GO GO:0005840 View Gene Set 1.21e-09 198 4.144e-07 39 ribosome amigo.geneontol...
GO GO:0031090 View Gene Set 1.323e-09 1905 4.418e-07 40 organelle membrane amigo.geneontol...
GO GO:0051603 View Gene Set 1.536e-09 346 5.006e-07 41 proteolysis involved in cellular protein catabolic process amigo.geneontol...
GO GO:0006399 View Gene Set 2.136e-09 118 6.795e-07 42 tRNA metabolic process amigo.geneontol...
GO GO:0016567 View Gene Set 2.215e-09 286 6.881e-07 43 protein ubiquitination amigo.geneontol...
GO GO:0010498 View Gene Set 2.347e-09 166 7.127e-07 44 proteasomal protein catabolic process amigo.geneontol...
GO GO:0006396 View Gene Set 2.718e-09 578 8.069e-07 45 RNA processing amigo.geneontol...
GO GO:0070647 View Gene Set 4.819e-09 356 1.4e-06 46 protein modification by small protein conjugation or removal amigo.geneontol...
GO GO:0008152 View Gene Set 5.125e-09 8439 1.457e-06 47 metabolic process amigo.geneontol...
GO GO:0006511 View Gene Set 5.62e-09 296 1.564e-06 48 ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0034470 View Gene Set 9.286e-09 193 2.532e-06 49 ncRNA processing amigo.geneontol...
GO GO:0019941 View Gene Set 1.056e-08 302 2.661e-06 50 modification-dependent protein catabolic process amigo.geneontol...
GO GO:0043161 View Gene Set 1.016e-08 162 2.661e-06 50 proteasomal ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0043632 View Gene Set 1.056e-08 302 2.661e-06 50 modification-dependent macromolecule catabolic process amigo.geneontol...
GO GO:0046907 View Gene Set 1.03e-08 753 2.661e-06 50 intracellular transport amigo.geneontol...
GO GO:0045333 View Gene Set 1.335e-08 100 3.304e-06 54 cellular respiration amigo.geneontol...
GO GO:0032446 View Gene Set 1.942e-08 310 4.717e-06 55 protein modification by small protein conjugation amigo.geneontol...
GO GO:0009057 View Gene Set 2.733e-08 570 6.405e-06 56 macromolecule catabolic process amigo.geneontol...
GO GO:0044260 View Gene Set 2.69e-08 5699 6.405e-06 56 cellular macromolecule metabolic process amigo.geneontol...
GO GO:0006418 View Gene Set 4.38e-08 45 9.752e-06 58 tRNA aminoacylation for protein translation amigo.geneontol...
GO GO:0043038 View Gene Set 4.38e-08 45 9.752e-06 58 amino acid activation amigo.geneontol...
GO GO:0043039 View Gene Set 4.38e-08 45 9.752e-06 58 tRNA aminoacylation amigo.geneontol...
GO GO:0044238 View Gene Set 4.612e-08 7629 1.01e-05 61 primary metabolic process amigo.geneontol...
GO GO:0004812 View Gene Set 4.933e-08 46 1.03e-05 62 aminoacyl-tRNA ligase activity amigo.geneontol...
GO GO:0016875 View Gene Set 4.933e-08 46 1.03e-05 62 ligase activity forming carbon-oxygen bonds amigo.geneontol...
GO GO:0016876 View Gene Set 4.933e-08 46 1.03e-05 62 ligase activity forming aminoacyl-tRNA and related compounds amigo.geneontol...
GO GO:0044265 View Gene Set 6.667e-08 479 1.361e-05 65 cellular macromolecule catabolic process amigo.geneontol...
GO GO:0031981 View Gene Set 6.723e-08 1518 1.361e-05 65 nuclear lumen amigo.geneontol...
GO GO:0043170 View Gene Set 7.038e-08 6274 1.403e-05 67 macromolecule metabolic process amigo.geneontol...
GO GO:0003824 View Gene Set 7.521e-08 5198 1.478e-05 68 catalytic activity amigo.geneontol...
GO GO:0044428 View Gene Set 1.542e-07 1938 2.985e-05 69 nuclear part amigo.geneontol...
GO GO:0051443 View Gene Set 1.732e-07 71 3.307e-05 70 positive regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0051437 View Gene Set 1.842e-07 64 3.466e-05 71 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0022900 View Gene Set 2.473e-07 115 4.525e-05 72 electron transport chain amigo.geneontol...
GO GO:0070469 View Gene Set 2.456e-07 77 4.525e-05 72 respiratory chain amigo.geneontol...
GO GO:0005829 View Gene Set 2.691e-07 1323 4.858e-05 74 cytosol amigo.geneontol...
GO GO:0033279 View Gene Set 3.783e-07 121 6.65e-05 75 ribosomal subunit amigo.geneontol...
GO GO:0008135 View Gene Set 3.781e-07 86 6.65e-05 75 translation factor activity nucleic acid binding amigo.geneontol...
GO GO:0003735 View Gene Set 4.147e-07 158 7.196e-05 77 structural constituent of ribosome amigo.geneontol...
GO GO:0006364 View Gene Set 4.942e-07 97 8.466e-05 78 rRNA processing amigo.geneontol...
GO GO:0006091 View Gene Set 5.141e-07 339 8.695e-05 79 generation of precursor metabolites and energy amigo.geneontol...
GO GO:0000502 View Gene Set 5.266e-07 63 8.795e-05 80 proteasome complex amigo.geneontol...
GO GO:0010467 View Gene Set 6.406e-07 3806 0.0001057 81 gene expression amigo.geneontol...
GO GO:0006413 View Gene Set 7.073e-07 62 0.0001152 82 translational initiation amigo.geneontol...
GO GO:0006417 View Gene Set 7.617e-07 151 0.0001212 83 regulation of translation amigo.geneontol...
GO GO:0051351 View Gene Set 7.554e-07 74 0.0001212 83 positive regulation of ligase activity amigo.geneontol...
GO GO:0000313 View Gene Set 8.108e-07 49 0.000126 85 organellar ribosome amigo.geneontol...
GO GO:0005761 View Gene Set 8.108e-07 49 0.000126 85 mitochondrial ribosome amigo.geneontol...
GO GO:0016874 View Gene Set 1.004e-06 436 0.0001542 87 ligase activity amigo.geneontol...
GO GO:0051082 View Gene Set 1.233e-06 113 0.0001873 88 unfolded protein binding amigo.geneontol...
GO GO:0015980 View Gene Set 1.264e-06 163 0.0001897 89 energy derivation by oxidation of organic compounds amigo.geneontol...
GO GO:0003743 View Gene Set 1.296e-06 52 0.0001925 90 translation initiation factor activity amigo.geneontol...
GO GO:0016072 View Gene Set 1.437e-06 101 0.0002109 91 rRNA metabolic process amigo.geneontol...
GO GO:0031398 View Gene Set 1.557e-06 95 0.0002262 92 positive regulation of protein ubiquitination amigo.geneontol...
GO GO:0051439 View Gene Set 1.795e-06 68 0.0002579 93 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0031145 View Gene Set 2.006e-06 64 0.0002851 94 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0070936 View Gene Set 2.559e-06 26 0.0003595 95 protein K48-linked ubiquitination amigo.geneontol...
GO GO:0005746 View Gene Set 2.583e-06 70 0.0003595 95 mitochondrial respiratory chain amigo.geneontol...
GO GO:0051436 View Gene Set 2.65e-06 62 0.0003651 97 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0022904 View Gene Set 5.566e-06 65 0.0007587 98 respiratory electron transport chain amigo.geneontol...
GO GO:0051438 View Gene Set 5.679e-06 82 0.0007664 99 regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0015935 View Gene Set 6.691e-06 59 0.0008939 100 small ribosomal subunit amigo.geneontol...
GO GO:0043234 View Gene Set 7.076e-06 2680 0.000936 101 protein complex amigo.geneontol...
GO GO:0015031 View Gene Set 7.863e-06 888 0.00103 102 protein transport amigo.geneontol...
GO GO:0048193 View Gene Set 1.033e-05 137 0.00134 103 Golgi vesicle transport amigo.geneontol...
GO GO:0005741 View Gene Set 1.109e-05 90 0.001424 104 mitochondrial outer membrane amigo.geneontol...
GO GO:0042773 View Gene Set 1.144e-05 57 0.001442 105 ATP synthesis coupled electron transport amigo.geneontol...
GO GO:0042775 View Gene Set 1.144e-05 57 0.001442 105 mitochondrial ATP synthesis coupled electron transport amigo.geneontol...
GO GO:0006508 View Gene Set 1.352e-05 783 0.001688 107 proteolysis amigo.geneontol...
GO GO:0006839 View Gene Set 1.375e-05 75 0.0017 108 mitochondrial transport amigo.geneontol...
GO GO:0045184 View Gene Set 1.492e-05 904 0.001828 109 establishment of protein localization amigo.geneontol...
GO GO:0051340 View Gene Set 1.74e-05 85 0.002113 110 regulation of ligase activity amigo.geneontol...
GO GO:0019787 View Gene Set 2.095e-05 210 0.002521 111 small conjugating protein ligase activity amigo.geneontol...
GO GO:0004842 View Gene Set 2.778e-05 191 0.003313 112 ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0070979 View Gene Set 2.918e-05 25 0.00345 113 protein K11-linked ubiquitination amigo.geneontol...
GO GO:0031396 View Gene Set 3.001e-05 121 0.003517 114 regulation of protein ubiquitination amigo.geneontol...
GO GO:0005793 View Gene Set 3.128e-05 52 0.003633 115 ER-Golgi intermediate compartment amigo.geneontol...
GO GO:0005747 View Gene Set 3.213e-05 46 0.003638 116 mitochondrial respiratory chain complex I amigo.geneontol...
GO GO:0030964 View Gene Set 3.213e-05 46 0.003638 116 NADH dehydrogenase complex amigo.geneontol...
GO GO:0045271 View Gene Set 3.213e-05 46 0.003638 116 respiratory chain complex I amigo.geneontol...
GO GO:0006120 View Gene Set 3.384e-05 43 0.0038 119 mitochondrial electron transport NADH to ubiquinone amigo.geneontol...
GO GO:0051352 View Gene Set 3.678e-05 66 0.004061 120 negative regulation of ligase activity amigo.geneontol...
GO GO:0051444 View Gene Set 3.678e-05 66 0.004061 120 negative regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0009295 View Gene Set 3.944e-05 31 0.004284 122 nucleoid amigo.geneontol...
GO GO:0042645 View Gene Set 3.944e-05 31 0.004284 122 mitochondrial nucleoid amigo.geneontol...
GO GO:0006626 View Gene Set 4.314e-05 32 0.004611 124 protein targeting to mitochondrion amigo.geneontol...
GO GO:0070585 View Gene Set 4.314e-05 32 0.004611 124 protein localization in mitochondrion amigo.geneontol...
GO GO:0051246 View Gene Set 4.482e-05 652 0.004752 126 regulation of protein metabolic process amigo.geneontol...
GO GO:0000049 View Gene Set 4.975e-05 24 0.005233 127 tRNA binding amigo.geneontol...
GO GO:0006903 View Gene Set 5.169e-05 22 0.005395 128 vesicle targeting amigo.geneontol...
GO GO:0003954 View Gene Set 5.636e-05 44 0.005747 129 NADH dehydrogenase activity amigo.geneontol...
GO GO:0008137 View Gene Set 5.636e-05 44 0.005747 129 NADH dehydrogenase (ubiquinone) activity amigo.geneontol...
GO GO:0050136 View Gene Set 5.636e-05 44 0.005747 129 NADH dehydrogenase (quinone) activity amigo.geneontol...
GO GO:0006368 View Gene Set 6.835e-05 49 0.006918 132 RNA elongation from RNA polymerase II promoter amigo.geneontol...
GO GO:0031397 View Gene Set 6.911e-05 78 0.006942 133 negative regulation of protein ubiquitination amigo.geneontol...
GO GO:0006119 View Gene Set 7.253e-05 104 0.007231 134 oxidative phosphorylation amigo.geneontol...
GO GO:0031968 View Gene Set 7.778e-05 110 0.007698 135 organelle outer membrane amigo.geneontol...
GO GO:0006886 View Gene Set 8.406e-05 439 0.008258 136 intracellular protein transport amigo.geneontol...
GO GO:0006612 View Gene Set 0.0001004 36 0.009667 137 protein targeting to membrane amigo.geneontol...
GO GO:0006613 View Gene Set 0.0001003 12 0.009667 137 cotranslational protein targeting to membrane amigo.geneontol...
GO GO:0051536 View Gene Set 0.0001013 54 0.009667 137 iron-sulfur cluster binding amigo.geneontol...
GO GO:0051540 View Gene Set 0.0001013 54 0.009667 137 metal cluster binding amigo.geneontol...
GO GO:0044249 View Gene Set 0.0001036 4326 0.009818 141 cellular biosynthetic process amigo.geneontol...
GO GO:0006446 View Gene Set 0.0001117 45 0.01051 142 regulation of translational initiation amigo.geneontol...
GO GO:0006414 View Gene Set 0.00012 104 0.01121 143 translational elongation amigo.geneontol...
GO GO:0007031 View Gene Set 0.0001296 22 0.01194 144 peroxisome organization amigo.geneontol...
GO GO:0008033 View Gene Set 0.0001294 78 0.01194 144 tRNA processing amigo.geneontol...
GO GO:0051650 View Gene Set 0.0001345 33 0.01231 146 establishment of vesicle localization amigo.geneontol...
GO GO:0043021 View Gene Set 0.0001356 39 0.01233 147 ribonucleoprotein binding amigo.geneontol...
GO GO:0044248 View Gene Set 0.0001672 1005 0.01509 148 cellular catabolic process amigo.geneontol...
GO GO:0009060 View Gene Set 0.0001745 34 0.01554 149 aerobic respiration amigo.geneontol...
GO GO:0048199 View Gene Set 0.0001742 12 0.01554 149 vesicle targeting to from or within Golgi amigo.geneontol...
GO GO:0009058 View Gene Set 0.0001857 4436 0.01643 151 biosynthetic process amigo.geneontol...
GO GO:0030134 View Gene Set 0.000187 16 0.01643 152 ER to Golgi transport vesicle amigo.geneontol...
GO GO:0019867 View Gene Set 0.0001886 115 0.01647 153 outer membrane amigo.geneontol...
GO GO:0030433 View Gene Set 0.0001929 27 0.01673 154 ER-associated protein catabolic process amigo.geneontol...
GO GO:0006354 View Gene Set 0.0001986 53 0.01712 155 RNA elongation amigo.geneontol...
GO GO:0016070 View Gene Set 0.0002227 2596 0.01907 156 RNA metabolic process amigo.geneontol...
GO GO:0032269 View Gene Set 0.0002354 205 0.02004 157 negative regulation of cellular protein metabolic process amigo.geneontol...
GO GO:0051188 View Gene Set 0.0002601 112 0.02185 158 cofactor biosynthetic process amigo.geneontol...
GO GO:0044445 View Gene Set 0.0002586 148 0.02185 158 cytosolic part amigo.geneontol...
GO GO:0007005 View Gene Set 0.0002779 139 0.02321 160 mitochondrion organization amigo.geneontol...
GO GO:0016879 View Gene Set 0.0002812 273 0.02333 161 ligase activity forming carbon-nitrogen bonds amigo.geneontol...
GO GO:0008380 View Gene Set 0.0003374 300 0.02783 162 RNA splicing amigo.geneontol...
GO GO:0016881 View Gene Set 0.0003445 245 0.02824 163 acid-amino acid ligase activity amigo.geneontol...
GO GO:0016558 View Gene Set 0.0003913 10 0.03188 164 protein import into peroxisome matrix amigo.geneontol...
GO GO:0048194 View Gene Set 0.0004096 10 0.03277 165 Golgi vesicle budding amigo.geneontol...
GO GO:0048200 View Gene Set 0.0004096 10 0.03277 165 Golgi transport vesicle coating amigo.geneontol...
GO GO:0048205 View Gene Set 0.0004096 10 0.03277 165 COPI coating of Golgi vesicle amigo.geneontol...
GO GO:0007006 View Gene Set 0.0004205 29 0.03344 168 mitochondrial membrane organization amigo.geneontol...
GO GO:0044085 View Gene Set 0.0004256 1167 0.03365 169 cellular component biogenesis amigo.geneontol...
GO GO:0051248 View Gene Set 0.0004287 218 0.03369 170 negative regulation of protein metabolic process amigo.geneontol...
GO GO:0005744 View Gene Set 0.0004485 12 0.03504 171 mitochondrial inner membrane presequence translocase complex amigo.geneontol...
GO GO:0016591 View Gene Set 0.0004739 77 0.03681 172 DNA-directed RNA polymerase II holoenzyme amigo.geneontol...
GO GO:0010608 View Gene Set 0.0004927 247 0.03805 173 posttranscriptional regulation of gene expression amigo.geneontol...
GO GO:0043574 View Gene Set 0.000543 15 0.04169 174 peroxisomal transport amigo.geneontol...
GO GO:0016417 View Gene Set 0.0005516 6 0.04211 175 S-acyltransferase activity amigo.geneontol...
GO GO:0005852 View Gene Set 0.0005633 14 0.04276 176 eukaryotic translation initiation factor 3 complex amigo.geneontol...
GO GO:0006891 View Gene Set 0.000609 19 0.04571 177 intra-Golgi vesicle-mediated transport amigo.geneontol...
GO GO:0070727 View Gene Set 0.0006083 503 0.04571 177 cellular macromolecule localization amigo.geneontol...
GO GO:0051649 View Gene Set 0.0006363 1116 0.04749 179 establishment of localization in cell amigo.geneontol...
GO GO:0000209 View Gene Set 0.0006483 42 0.04812 180 protein polyubiquitination amigo.geneontol...

Gene Set Collection: Broad.c1.CYTOBAND

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad chr19p13 View Gene Set 0.0001114 514 0.03633 1 Genes in cytogenetic band chr19p13 www.broad.mit.e...

Gene Set Collection: Broad.c2.CGP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP View Gene Set 1.186e-33 1353 2.836e-30 1 Genes up-regulated in CD34+ [Gene ID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients compared to those from normal donors. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN View Gene Set 8.867e-25 920 1.061e-21 2 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h. www.broad.mit.e...
Broad MOOTHA_MITOCHONDRIA View Gene Set 1.348e-20 433 1.075e-17 3 Mitochondrial genes www.broad.mit.e...
Broad MOOTHA_HUMAN_MITODB_6_2002 View Gene Set 3.272e-19 420 1.957e-16 4 Mitochondrial genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN View Gene Set 2.066e-18 832 9.885e-16 5 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. www.broad.mit.e...
Broad SHEN_SMARCA2_TARGETS_UP View Gene Set 1.723e-16 406 6.867e-14 6 Genes whose expression positively correlated with that of SMARCA2 [Gene ID=6595] in prostate cancer samples. www.broad.mit.e...
Broad CAIRO_HEPATOBLASTOMA_CLASSES_UP View Gene Set 6.346e-15 577 2.169e-12 7 Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). www.broad.mit.e...
Broad BENPORATH_MYC_MAX_TARGETS View Gene Set 4.878e-14 768 1.458e-11 8 Set 'Myc targets2': targets of c-Myc [Gene ID=4609] and Max [Gene ID=4149] identified by ChIP on chip in a Burkitt???s lymphoma cell line; overlap set. www.broad.mit.e...
Broad LIU_SOX4_TARGETS_DN View Gene Set 6.684e-14 297 1.776e-11 9 Genes down-regulated in LNCaP cells (prostate cancer) by overexpression of SOX4 [Gene ID=6659] and up-regulated by its RNAi knockdown. www.broad.mit.e...
Broad ELVIDGE_HYPOXIA_DN View Gene Set 2.342e-13 136 5.603e-11 10 Genes down-regulated in MCF7 cells (breast cancer) under hypoxia conditions. www.broad.mit.e...
Broad WONG_MITOCHONDRIA_GENE_MODULE View Gene Set 3.282e-13 208 7.136e-11 11 Genes that comprise the mitochondria gene module www.broad.mit.e...
Broad DANG_BOUND_BY_MYC View Gene Set 4.637e-13 1045 9.244e-11 12 Genes whose promoters are bound by MYC [Gene ID=4609] according to MYC Target Gene Database. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM View Gene Set 7.106e-13 154 1.307e-10 13 Cluster 7: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] and down-regulated by the combination of MYC and serum. www.broad.mit.e...
Broad BLUM_RESPONSE_TO_SALIRASIB_UP View Gene Set 2.086e-12 240 3.564e-10 14 Selected genes up-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [Gene ID=3265]. www.broad.mit.e...
Broad MOOTHA_PGC View Gene Set 3.366e-11 329 5.367e-09 15 Genes up-regulated in differentiating C2C12 cells (myoblasts) upon expression of PPARGC1A [Gene ID=10891] off an adenoviral vector. www.broad.mit.e...
Broad ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP View Gene Set 4.29e-11 806 6.413e-09 16 Genes up-regulated in liver tumor compared to the normal adjacent tissue. www.broad.mit.e...
Broad GRADE_COLON_CANCER_UP View Gene Set 1.32e-10 711 1.857e-08 17 Up-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples. www.broad.mit.e...
Broad GARY_CD5_TARGETS_UP View Gene Set 4.136e-10 463 5.496e-08 18 Genes up-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. www.broad.mit.e...
Broad PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_UP View Gene Set 8.65e-10 63 1.089e-07 19 Antigen processing and presentation genes up-regulated in JY cells (B lymphocytes) treated with TSA [PubChem=5562]. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 View Gene Set 9.899e-10 131 1.184e-07 20 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 14. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP View Gene Set 1.391e-09 869 1.584e-07 21 Genes up-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 View Gene Set 4.024e-09 165 4.375e-07 22 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 17. www.broad.mit.e...
Broad WEI_MYCN_TARGETS_WITH_E_BOX View Gene Set 1.024e-08 757 1.065e-06 23 Genes whose promoters contain E-box motifs and whose expression changed in MYCN-3 cells (neuroblastoma) upon induction of MYCN [Gene ID=4613]. www.broad.mit.e...
Broad STEIN_ESRRA_TARGETS_UP View Gene Set 1.207e-08 368 1.203e-06 24 Genes up-regulated by ESRRA [Gene ID=2101] only. www.broad.mit.e...
Broad STEIN_ESRRA_TARGETS View Gene Set 1.787e-08 508 1.71e-06 25 Genes regulated by ESRRA [Gene ID=2101] in MCF-7 cells (breast cancer). www.broad.mit.e...
Broad BORCZUK_MALIGNANT_MESOTHELIOMA_UP View Gene Set 2.173e-08 290 2e-06 26 Genes up-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma. www.broad.mit.e...
Broad SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY View Gene Set 4.849e-08 31 4.296e-06 27 Cluster 3: genes strongly up-regulated in B493-6 cells (B lymphocytes) by a combination of MYC [Gene ID=4609] and serum but not by each of them alone. www.broad.mit.e...
Broad STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN View Gene Set 6.095e-08 437 5.207e-06 28 Genes down-regulated in prefrontal cortex (PFC) of mice carrying a hemizygotic microdeletion in the 22q11.2 region. www.broad.mit.e...
Broad MILI_PSEUDOPODIA_CHEMOTAXIS_DN View Gene Set 7.348e-08 430 6.061e-06 29 Transcripts depleted in pseudopodia of NIH/3T3 cells (fibroblast) in response to the chemotactic migration stimulus by lysophosphatidic acid (LPA) [PubChem=3988]. www.broad.mit.e...
Broad MOOTHA_VOXPHOS View Gene Set 1.052e-07 82 8.389e-06 30 Genes involved in oxidative phosphorylation; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. www.broad.mit.e...
Broad MILI_PSEUDOPODIA_HAPTOTAXIS_DN View Gene Set 1.918e-07 607 1.48e-05 31 Transcripts depleted from pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin FN1 [Gene ID=2335]. www.broad.mit.e...
Broad BLALOCK_ALZHEIMERS_DISEASE_DN View Gene Set 2.117e-07 1209 1.583e-05 32 Genes down-regulated in brain from patients with Alzheimer's disease. www.broad.mit.e...
Broad PUJANA_BRCA1_PCC_NETWORK View Gene Set 3.945e-07 1582 2.859e-05 33 Genes constituting the BRCA1-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA1 [Gene ID=672] across a compendium of normal tissues. www.broad.mit.e...
Broad GARY_CD5_TARGETS_DN View Gene Set 5.964e-07 415 4.196e-05 34 Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. www.broad.mit.e...
Broad ELVIDGE_HIF1A_TARGETS_UP View Gene Set 1.006e-06 64 6.879e-05 35 Genes up-regulated in MCF7 cells (breast cancer) after knockdown of HIF1A [Gene ID=3091] by RNAi. www.broad.mit.e...
Broad RAMALHO_STEMNESS_UP View Gene Set 1.075e-06 192 7.143e-05 36 Genes enriched in embryonic neural and hematopoietic stem cells. www.broad.mit.e...
Broad SCHLOSSER_SERUM_RESPONSE_AUGMENTED_BY_MYC View Gene Set 1.164e-06 101 7.41e-05 37 Cluster 2: genes up-regulated in B493-6 cells (B lymphocytes) by serum alone or in combination with MYC [Gene ID=4609] but not by MYC alone. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7 View Gene Set 1.177e-06 65 7.41e-05 37 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 7. www.broad.mit.e...
Broad SCHLOSSER_SERUM_RESPONSE_DN View Gene Set 1.583e-06 666 9.564e-05 39 Cluster 4: genes down-regulated in B493-6 cells (B lymphocytes) upon serum stimulation but not affected by MYC [Gene ID=4609]. www.broad.mit.e...
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN View Gene Set 1.599e-06 571 9.564e-05 39 Genes down-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP View Gene Set 2.716e-06 45 0.0001584 41 Cluster 5: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] alone or in combination with serum but not by serum alone. www.broad.mit.e...
Broad AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP View Gene Set 3.123e-06 288 0.0001779 42 Up-regulated genes whose expression correlates with copy number gains in pancreatic adenocarcinoma cell lines and primary tumor specimens. www.broad.mit.e...
Broad MORI_PLASMA_CELL_UP View Gene Set 3.832e-06 37 0.0002131 43 Up-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: plasma cell. www.broad.mit.e...
Broad TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP View Gene Set 6.238e-06 76 0.0003391 44 Genes up-regulated in plasma cells compared with B lymphocytes. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_24HR_DN View Gene Set 1.388e-05 208 0.0007377 45 Genes down-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h. www.broad.mit.e...
Broad WANG_LMO4_TARGETS_DN View Gene Set 2.129e-05 327 0.001107 46 Genes down-regulated in MCF7 cells (breast cancer) engineered to conditionally express LMO4 [Gene ID=8543] by a Tet Off system. www.broad.mit.e...
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_UP View Gene Set 2.42e-05 301 0.001231 47 Genes up-regulated in fibroblasts expressing mutant forms of ERCC3 [Gene ID=2071] after UV irradiation. www.broad.mit.e...
Broad SESTO_RESPONSE_TO_UV_C0 View Gene Set 2.762e-05 106 0.001376 48 Cluster 0: genes changed in primary keratinocytes by UVB irradiation. www.broad.mit.e...
Broad DAIRKEE_TERT_TARGETS_UP View Gene Set 3.13e-05 317 0.001528 49 Genes up-regulated in non-spontaneously immortalizing (NSI) primary breast cancer tumor cultures upon expression of TERT [Gene ID=7015] off a retroviral vector. www.broad.mit.e...
Broad PENG_GLUTAMINE_DEPRIVATION_DN View Gene Set 3.248e-05 84 0.001554 50 Genes down-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation. www.broad.mit.e...
Broad FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP View Gene Set 3.372e-05 147 0.001582 51 Genes upreglated in peripheral blood lymphocytes (PBL) from patients with well functioning kidneys more than 1-year post transplant compared to those from normal living kidney donors. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 View Gene Set 3.754e-05 158 0.001727 52 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 13. www.broad.mit.e...
Broad JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_UP View Gene Set 4.24e-05 45 0.001913 53 Up-regulated genes distinguishing between breast cancer tumors with mutated BRCA1 [Gene ID=672] from those with mutated BRCA2 [Gene ID=675]. www.broad.mit.e...
Broad ACEVEDO_LIVER_CANCER_UP View Gene Set 5.327e-05 915 0.00236 54 Genes up-regulated in hepatocellular carcinoma (HCC) compared to normal liver samples. www.broad.mit.e...
Broad GOLDRATH_HOMEOSTATIC_PROLIFERATION View Gene Set 6.139e-05 154 0.00267 55 Up-regulated in CD8+ [Gene ID=925] T lymphocytes undergoing homeostatic proliferation (HP) versus the naive cells; these genes are not up-regulated versus effector or memory cell population. www.broad.mit.e...
Broad MILI_PSEUDOPODIA_HAPTOTAXIS_UP View Gene Set 6.489e-05 452 0.002772 56 Transcripts enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin FN1 [Gene ID=2335]. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP View Gene Set 8.707e-05 184 0.003654 57 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G3 defined by unsupervised clustering. www.broad.mit.e...
Broad PENG_RAPAMYCIN_RESPONSE_DN View Gene Set 9.272e-05 69 0.003824 58 Genes down-regulated in BJUB cells (B-lymphoma) in response to rapamycin [PubChem=6610346] treatment. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 View Gene Set 0.0001119 93 0.004537 59 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 11. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_UP View Gene Set 0.0001182 104 0.004711 60 Genes up-regulated in metastatic breast cancer tumors having type 2 amplification in the 20q13 region; involves MYBL2 STK6 and ZNF217 [Gene ID=4605 6790 7764] www.broad.mit.e...
Broad DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER View Gene Set 0.0001276 91 0.005003 61 The lung adenocarcinoma TSP (tumor sequencing project) genes showing strong correlation between DNA copy number variation and gene expression. www.broad.mit.e...
Broad CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP View Gene Set 0.0001309 51 0.00505 62 Protein biosynthesis transport or catabolism genes up-regulated in hyperploid multiple myeloma (MM) compared to the non-hyperploid MM samples. www.broad.mit.e...
Broad MOOTHA_TCA View Gene Set 0.0001482 15 0.005626 63 Tricarboxylic acid related genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. www.broad.mit.e...
Broad LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER View Gene Set 0.000158 167 0.005905 64 Overexpressed genes with amplified copy number across 27 non-small cell lung cancer (NSCLC) cell lines. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN View Gene Set 0.0001762 308 0.006483 65 Genes down-regulated in non-metastatic breast cancer tumors having type 1 amplification in the 20q13 region; involves ZNF217 [Gene ID=7764] locus only. www.broad.mit.e...
Broad DOUGLAS_BMI1_TARGETS_UP View Gene Set 0.0001805 497 0.006543 66 Genes up-regulated in A4573 cells (Ewing's sarcoma ESFT) after knockdown of BMI1 [Gene ID=648] by RNAi. www.broad.mit.e...
Broad FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN View Gene Set 0.0001897 532 0.006774 67 Genes differentially expressed in kidney biopsies from patients with acute transplant rejection compared to the biopsies from patients with well functioning kidneys more than 1-year post transplant. www.broad.mit.e...
Broad IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR View Gene Set 0.0002088 100 0.007345 68 Genes in the expression cluster 'Early Progenitors Shared': up-regulated in hematopoietic progenitors from adult bone marrow and from fetal liver. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP View Gene Set 0.0002358 589 0.008176 69 Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. www.broad.mit.e...
Broad SHEPARD_CRUSH_AND_BURN_MUTANT_UP View Gene Set 0.0002993 135 0.01001 70 Human orthologs of genes up-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [Gene ID=4605]. www.broad.mit.e...
Broad ELLWOOD_MYC_TARGETS_DN View Gene Set 0.0003048 34 0.01001 70 Genes down-regulated in transgenic mice expressing human MYC [Gene ID=4609] in prostate. www.broad.mit.e...
Broad HSIAO_HOUSEKEEPING_GENES View Gene Set 0.0003054 384 0.01001 70 Housekeeping genes identified as expressed across 19 normal tissues. www.broad.mit.e...
Broad ROME_INSULIN_TARGETS_IN_MUSCLE_UP View Gene Set 0.000305 89 0.01001 70 Genes up-regulated by 3 h of euglycemic hyperinsulinemic clamp in the vastus lateralis muscle of healthy lean subjects. www.broad.mit.e...
Broad WONG_PROTEASOME_GENE_MODULE View Gene Set 0.0003345 46 0.01081 74 Genes that comprise the proteasome gene module www.broad.mit.e...
Broad LUI_THYROID_CANCER_CLUSTER_3 View Gene Set 0.0003492 26 0.01114 75 Cluster 3: genes with similar expression profiles across follicular thyrorid carcinoma (FTC) samples; genes in this cluster correlated well with the presence of PAX8-PPARG [Gene ID=7849 5468] fusion protein. www.broad.mit.e...
Broad CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP View Gene Set 0.0004276 34 0.01346 76 Genes in the AKT1 [Gene ID=207] pathway which are independent of MTOR [Gene ID=2475] insensitive to RAD001 (everolimus) [PubChem=6442177]. www.broad.mit.e...
Broad PENG_LEUCINE_DEPRIVATION_DN View Gene Set 0.0005242 50 0.01629 77 Genes down-regulated in BJAB cells (B-lymphoma) after leucine [PubChem=857] deprivation. www.broad.mit.e...
Broad NOUZOVA_TRETINOIN_AND_H4_ACETYLATION View Gene Set 0.0005543 124 0.017 78 Genes whose CpG islands showed greatly increased histone H4 acetylation in NB4 cells (acute promyelocytic leukemia APL) upon treatment with tretinoin [PubChem=5538]. www.broad.mit.e...
Broad SENESE_HDAC1_TARGETS_UP View Gene Set 0.0005851 427 0.01772 79 Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [Gene ID=3065] by RNAi. www.broad.mit.e...
Broad MANALO_HYPOXIA_DN View Gene Set 0.0006517 276 0.01949 80 Genes down-regulated in response to both hypoxia and overexpression of an active form of HIF1A [Gene ID=3091]. www.broad.mit.e...
Broad ENK_UV_RESPONSE_KERATINOCYTE_DN View Gene Set 0.0006948 475 0.02002 81 Genes down-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation. www.broad.mit.e...
Broad LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP View Gene Set 0.0006883 168 0.02002 81 Genes with copy number gains in primary neuroblastoma tumors. www.broad.mit.e...
Broad LU_AGING_BRAIN_UP View Gene Set 0.000679 146 0.02002 81 Genes up-regulated in postmortem brain frontal cortex samples from old subjects compared to those from the young ones. www.broad.mit.e...
Broad MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN View Gene Set 0.0007976 121 0.02271 84 Genes distinguishing in multiple myeloma (MM) samples with lower expression of TACI [Gene ID=23495]. www.broad.mit.e...
Broad NIKOLSKY_BREAST_CANCER_22Q13_AMPLICON View Gene Set 0.0008262 17 0.02325 85 Genes within amplicon 22q13 identified in a copy number alterations study of 191 breast tumor samples. www.broad.mit.e...
Broad LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN View Gene Set 0.0008617 742 0.02369 86 Genes with copy number losses in primary neuroblastoma tumors. www.broad.mit.e...
Broad GUTIERREZ_MULTIPLE_MYELOMA_DN View Gene Set 0.0008584 34 0.02369 86 Genes exclusively down-regulated in plasma cells from MM (multiple myeloma) patients but with a similiar expression pattern in the normal cells and in the cells from WM (Waldenstroem's macroblobulinemia) patients. www.broad.mit.e...
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP View Gene Set 0.001128 17 0.03009 88 Genes from the red module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC). www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN View Gene Set 0.001119 46 0.03009 88 Cluster 6: genes down-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] in combination with serum but not affected by serum alone; they are also up-regulated by MYC alone. www.broad.mit.e...
Broad SCHUHMACHER_MYC_TARGETS_UP View Gene Set 0.001132 68 0.03009 88 Genes up-regulated in P493-6 cells (Burkitt's lymphoma) induced to express MYC [Gene ID=4609]. www.broad.mit.e...
Broad BILD_MYC_ONCOGENIC_SIGNATURE View Gene Set 0.001173 187 0.03082 91 Genes selected in supervised analyses to discriminate cells expressing c-Myc [Gene ID=4609] from control cells expressing GFP. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_6HR_DN View Gene Set 0.001244 160 0.03164 92 Genes down-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 6h. www.broad.mit.e...
Broad AMIT_EGF_RESPONSE_480_HELA View Gene Set 0.001243 159 0.03164 92 Genes whose expression peaked at 480 min after stimulation of HeLa cells with EGF [Gene ID=1950]. www.broad.mit.e...
Broad BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS View Gene Set 0.001228 805 0.03164 92 Transcripts in hematopoietic stem cells (HSC) which are trans-regulated (i.e. modulated by a QTL (quantitative trait locus) not in a close proximity to the gene). www.broad.mit.e...
Broad ACEVEDO_METHYLATED_IN_LIVER_CANCER_UP View Gene Set 0.001286 2268 0.03238 95 Genes whose DNA is hypo-methylated in hepatocellular carcinoma (HCC) compared to normal liver. www.broad.mit.e...
Broad PARENT_MTOR_SIGNALING_UP View Gene Set 0.001341 541 0.03277 96 Genes up-regulated in HepaRG cells (liver cancer) expressing constituvely active form of MTOR [Gene ID=2475]. www.broad.mit.e...
Broad PENG_LEUCINE_DEPRIVATION_UP View Gene Set 0.001343 22 0.03277 96 Genes up-regulated in BJAB cells (B-lymphoma) after leucine [PubChem=857] deprivation. www.broad.mit.e...
Broad CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP View Gene Set 0.001333 47 0.03277 96 Genes up-regulated by 2-methoxyestradiol (2ME2) [PubChem=1573] in the MM.1S cell line (multiple myeloma) sensitive to dexamethasone [PubChem=5743]. www.broad.mit.e...
Broad ENK_UV_RESPONSE_KERATINOCYTE_UP View Gene Set 0.001424 517 0.0344 99 Genes up-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation. www.broad.mit.e...
Broad WELCSH_BRCA1_TARGETS_1_UP View Gene Set 0.001452 171 0.03472 100 Upregulated by induction of exogenous BRCA1 in EcR-293 cells www.broad.mit.e...
Broad PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP View Gene Set 0.001516 257 0.03555 101 Genes up-regulated in post-GC BCL6 [Gene ID=604] dependent B cell non-Hodgkin's lymphoma (B-NHL) vs MYC [Gene ID=4609] driven pre-GC lymphoma; GC = germinal center. www.broad.mit.e...
Broad KAYO_AGING_MUSCLE_DN View Gene Set 0.001514 107 0.03555 101 Downregulated in the vastus lateralis muscle of aged vs young adult rhesus monkeys www.broad.mit.e...
Broad NAGY_PCAF_COMPONENTS_HUMAN View Gene Set 0.001563 5 0.03629 103 Composition of the 2 MDa human PCAF complex. www.broad.mit.e...
Broad MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_22 View Gene Set 0.001623 11 0.03733 104 Amplification hot spot 22: colocolized fragile sites and cancer genes in the 22q11.1-q13s region. www.broad.mit.e...
Broad KIM_GASTRIC_CANCER_CHEMOSENSITIVITY View Gene Set 0.001883 97 0.04291 105 Genes up-regulated in gastric cancer patients refractory to chemotherapy treatment with 5-fluorouracil and cisplatin [PubChem=3385 2767] compared to the sensitive state. www.broad.mit.e...
Broad PUJANA_CHEK2_PCC_NETWORK View Gene Set 0.002061 744 0.04651 106 Genes constituting the CHEK2-PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient PCC >= 0.4) with that of CHEK2 [Gene ID=11200]. www.broad.mit.e...
Broad OSMAN_BLADDER_CANCER_UP View Gene Set 0.002187 387 0.04889 107 Genes up-regulated in blood samples from bladder cancer patients. www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.BIOCARTA

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad BIOCARTA_PROTEASOME_PATHWAY View Gene Set 4.91e-05 19 0.01065 1 Proteasome Complex www.broad.mit.e...
Broad BIOCARTA_MTOR_PATHWAY View Gene Set 0.0001565 23 0.01132 2 mTOR Signaling Pathway www.broad.mit.e...
Broad BIOCARTA_IGF1MTOR_PATHWAY View Gene Set 0.0001499 20 0.01132 2 Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway www.broad.mit.e...
Broad BIOCARTA_IGF1R_PATHWAY View Gene Set 0.0003078 23 0.0167 4 Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation www.broad.mit.e...
Broad BIOCARTA_INTEGRIN_PATHWAY View Gene Set 0.0007593 38 0.03295 5 Integrin Signaling Pathway www.broad.mit.e...
Broad BIOCARTA_EIF4_PATHWAY View Gene Set 0.0009488 24 0.03431 6 Regulation of eIF4e and p70 S6 Kinase www.broad.mit.e...
Broad BIOCARTA_EIF_PATHWAY View Gene Set 0.001335 16 0.04137 7 Eukaryotic protein translation www.broad.mit.e...
Broad BIOCARTA_HCMV_PATHWAY View Gene Set 0.001573 17 0.04268 8 Human Cytomegalovirus and Map Kinase Pathways www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.KEGG

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad KEGG_OXIDATIVE_PHOSPHORYLATION View Gene Set 1.073e-06 135 6.394e-05 1 Oxidative phosphorylation www.broad.mit.e...
Broad KEGG_AMINOACYL_TRNA_BIOSYNTHESIS View Gene Set 1.375e-06 41 6.394e-05 1 Aminoacyl-tRNA biosynthesis www.broad.mit.e...
Broad KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS View Gene Set 7.478e-07 138 6.394e-05 1 Ubiquitin mediated proteolysis www.broad.mit.e...
Broad KEGG_PARKINSONS_DISEASE View Gene Set 5.082e-07 133 6.394e-05 1 Parkinson's disease www.broad.mit.e...
Broad KEGG_HUNTINGTONS_DISEASE View Gene Set 3.054e-06 185 0.0001136 5 Huntington's disease www.broad.mit.e...
Broad KEGG_PROTEASOME View Gene Set 1.588e-05 48 0.0004921 6 Proteasome www.broad.mit.e...
Broad KEGG_ALZHEIMERS_DISEASE View Gene Set 5.585e-05 169 0.001484 7 Alzheimer's disease www.broad.mit.e...
Broad KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION View Gene Set 0.0001513 44 0.003518 8 Vasopressin-regulated water reabsorption www.broad.mit.e...
Broad KEGG_CITRATE_CYCLE_TCA_CYCLE View Gene Set 0.0005108 32 0.008798 9 Citrate cycle (TCA cycle) www.broad.mit.e...
Broad KEGG_PROTEIN_EXPORT View Gene Set 0.0005053 24 0.008798 9 Protein export www.broad.mit.e...
Broad KEGG_INSULIN_SIGNALING_PATHWAY View Gene Set 0.0005203 137 0.008798 9 Insulin signaling pathway www.broad.mit.e...
Broad KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY View Gene Set 0.001102 79 0.01708 12 Fc epsilon RI signaling pathway www.broad.mit.e...
Broad KEGG_RIBOSOME View Gene Set 0.002842 88 0.04066 13 Ribosome www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.REACTOME

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC View Gene Set 1.507e-08 57 3.239e-06 1 Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_PROTEINS View Gene Set 1.24e-08 215 3.239e-06 1 Genes involved in Metabolism of proteins www.broad.mit.e...
Broad REACTOME_GENE_EXPRESSION View Gene Set 2.691e-08 415 3.857e-06 3 Genes involved in Gene Expression www.broad.mit.e...
Broad REACTOME_TRNA_AMINOACYLATION View Gene Set 7.589e-08 40 8.158e-06 4 Genes involved in tRNA Aminoacylation www.broad.mit.e...
Broad REACTOME_DIABETES_PATHWAYS View Gene Set 1.029e-07 383 8.231e-06 5 Genes involved in Diabetes pathways www.broad.mit.e...
Broad REACTOME_ELECTRON_TRANSPORT_CHAIN View Gene Set 1.148e-07 75 8.231e-06 5 Genes involved in Electron Transport Chain www.broad.mit.e...
Broad REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION View Gene Set 2.319e-07 23 1.425e-05 7 Genes involved in Cytosolic tRNA aminoacylation www.broad.mit.e...
Broad REACTOME_INTEGRATION_OF_ENERGY_METABOLISM View Gene Set 5.5e-07 229 2.956e-05 8 Genes involved in Integration of energy metabolism www.broad.mit.e...
Broad REACTOME_TRANSLATION View Gene Set 1.01e-06 120 4.824e-05 9 Genes involved in Translation www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION View Gene Set 1.478e-06 188 6.356e-05 10 Genes involved in Transcription www.broad.mit.e...
Broad REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE View Gene Set 2.014e-06 47 7.873e-05 11 Genes involved in Regulation of ornithine decarboxylase (ODC) www.broad.mit.e...
Broad REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 View Gene Set 3.566e-06 48 0.0001194 12 Genes involved in SCF-beta-TrCP mediated degradation of Emi1 www.broad.mit.e...
Broad REACTOME_SIGNALING_BY_WNT View Gene Set 3.611e-06 58 0.0001194 12 Genes involved in Signaling by Wnt www.broad.mit.e...
Broad REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION View Gene Set 4.471e-06 161 0.000134 14 Genes involved in Glucose Regulation of Insulin Secretion www.broad.mit.e...
Broad REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G View Gene Set 4.673e-06 47 0.000134 14 Genes involved in Vif-mediated degradation of APOBEC3G www.broad.mit.e...
Broad REACTOME_PYRUVATE_METABOLISM_AND_TCA_CYCLE View Gene Set 9.499e-06 36 0.0002553 16 Genes involved in Pyruvate metabolism and TCA cycle www.broad.mit.e...
Broad REACTOME_HIV_INFECTION View Gene Set 1.056e-05 183 0.0002671 17 Genes involved in HIV Infection www.broad.mit.e...
Broad REACTOME_REGULATION_OF_APC_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE View Gene Set 1.182e-05 71 0.0002824 18 Genes involved in Regulation of APC/C activators between G1/S and early anaphase www.broad.mit.e...
Broad REACTOME_CDC20_PHOSPHO_APC_MEDIATED_DEGRADATION_OF_CYCLIN_A View Gene Set 1.363e-05 63 0.0003084 19 Genes involved in Cdc20:Phospho-APC/C mediated degradation of Cyclin A www.broad.mit.e...
Broad REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX View Gene Set 1.51e-05 49 0.0003093 20 Genes involved in Formation of the ternary complex and subsequently the 43S complex www.broad.mit.e...
Broad REACTOME_INSULIN_SYNTHESIS_AND_SECRETION View Gene Set 1.478e-05 129 0.0003093 20 Genes involved in Insulin Synthesis and Secretion www.broad.mit.e...
Broad REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT View Gene Set 1.657e-05 106 0.0003238 22 Genes involved in GTP hydrolysis and joining of the 60S ribosomal subunit www.broad.mit.e...
Broad REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE View Gene Set 2.285e-05 43 0.0004272 23 Genes involved in p53-Independent DNA Damage Response www.broad.mit.e...
Broad REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION View Gene Set 2.756e-05 56 0.0004938 24 Genes involved in Translation initiation complex formation www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING_MINOR_PATHWAY View Gene Set 5.531e-05 38 0.0009513 25 Genes involved in mRNA Splicing - Minor Pathway www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_III_AND_MITOCHONDRIAL_TRANSCRIPTION View Gene Set 6.267e-05 120 0.001036 26 Genes involved in RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription www.broad.mit.e...
Broad REACTOME_HIV1_TRANSCRIPTION_ELONGATION View Gene Set 6.781e-05 41 0.00108 27 Genes involved in HIV-1 Transcription Elongation www.broad.mit.e...
Broad REACTOME_STABILIZATION_OF_P53 View Gene Set 9.653e-05 46 0.001482 28 Genes involved in Stabilization of p53 www.broad.mit.e...
Broad REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION View Gene Set 0.0001064 100 0.001578 29 Genes involved in Influenza Viral RNA Transcription and Replication www.broad.mit.e...
Broad REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX View Gene Set 0.0001214 52 0.001741 30 Genes involved in CDT1 association with the CDC6:ORC:origin complex www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_AMINO_ACIDS View Gene Set 0.0001373 162 0.001905 31 Genes involved in Metabolism of amino acids www.broad.mit.e...
Broad REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS View Gene Set 0.0001664 120 0.002236 32 Genes involved in Host Interactions of HIV factors www.broad.mit.e...
Broad REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS View Gene Set 0.0002408 95 0.003138 33 Genes involved in Formation of a pool of free 40S subunits www.broad.mit.e...
Broad REACTOME_APOPTOSIS View Gene Set 0.000292 129 0.003693 34 Genes involved in Apoptosis www.broad.mit.e...
Broad REACTOME_FORMATION_OF_THE_EARLY_ELONGATION_COMPLEX View Gene Set 0.0003037 32 0.003731 35 Genes involved in Formation of the Early Elongation Complex www.broad.mit.e...
Broad REACTOME_CHOLESTEROL_BIOSYNTHESIS View Gene Set 0.000345 21 0.004009 36 Genes involved in Cholesterol biosynthesis www.broad.mit.e...
Broad REACTOME_TAT_MEDIATED_HIV1_ELONGATION_ARREST_AND_RECOVERY View Gene Set 0.0003391 30 0.004009 36 Genes involved in Tat-mediated HIV-1 elongation arrest and recovery www.broad.mit.e...
Broad REACTOME_COPI_MEDIATED_TRANSPORT View Gene Set 0.0004096 10 0.004635 38 Genes involved in COPI Mediated Transport www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME View Gene Set 0.0004879 59 0.00538 39 Genes involved in Transcription of the HIV genome www.broad.mit.e...
Broad REACTOME_INFLUENZA_LIFE_CYCLE View Gene Set 0.00053 137 0.005614 40 Genes involved in Influenza Life Cycle www.broad.mit.e...
Broad REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21 View Gene Set 0.0005353 52 0.005614 40 Genes involved in SCF(Skp2)-mediated degradation of p2721 www.broad.mit.e...
Broad REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION View Gene Set 0.0006121 24 0.006123 42 Genes involved in Nuclear Events (kinase and transcription factor activation) www.broad.mit.e...
Broad REACTOME_PACKAGING_OF_TELOMERE_ENDS View Gene Set 0.0006123 49 0.006123 42 Genes involved in Packaging Of Telomere Ends www.broad.mit.e...
Broad REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT View Gene Set 0.0006654 23 0.006358 44 Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat www.broad.mit.e...
Broad REACTOME_CITRIC_ACID_CYCLE View Gene Set 0.000652 19 0.006358 44 Genes involved in Citric acid cycle (TCA cycle) www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION View Gene Set 0.0008586 34 0.008026 46 Genes involved in RNA Polymerase III Transcription www.broad.mit.e...
Broad REACTOME_HIV1_TRANSCRIPTION_INITIATION View Gene Set 0.0009357 39 0.008561 47 Genes involved in HIV-1 Transcription Initiation www.broad.mit.e...
Broad REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ View Gene Set 0.001027 58 0.008941 48 Genes involved in Cyclin E associated events during G1/S transition www.broad.mit.e...
Broad REACTOME_REGULATION_OF_INSULIN_SECRETION View Gene Set 0.00104 212 0.008941 48 Genes involved in Regulation of Insulin Secretion www.broad.mit.e...
Broad REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE View Gene Set 0.001029 103 0.008941 48 Genes involved in TRKA signalling from the plasma membrane www.broad.mit.e...
Broad REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS View Gene Set 0.001219 14 0.01028 51 Genes involved in Viral Messenger RNA Synthesis www.broad.mit.e...
Broad REACTOME_PYRUVATE_METABOLISM View Gene Set 0.001384 18 0.01144 52 Genes involved in Pyruvate metabolism www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION View Gene Set 0.001863 29 0.01511 53 Genes involved in RNA Polymerase III Transcription Initiation www.broad.mit.e...
Broad REACTOME_SIGNALLING_BY_NGF View Gene Set 0.002069 216 0.01647 54 Genes involved in Signalling by NGF www.broad.mit.e...
Broad REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS View Gene Set 0.002324 124 0.01817 55 Genes involved in Elongation and Processing of Capped Transcripts www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION View Gene Set 0.002605 83 0.02 56 Genes involved in RNA Polymerase II Transcription www.broad.mit.e...
Broad REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT View Gene Set 0.003278 142 0.02473 57 Genes involved in Formation and Maturation of mRNA Transcript www.broad.mit.e...
Broad REACTOME_CONVERSION_FROM_APC_CDC20_TO_APC_CDH1_IN_LATE_ANAPHASE View Gene Set 0.003566 17 0.02644 58 Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase www.broad.mit.e...
Broad REACTOME_ERK_MAPK_TARGETS View Gene Set 0.003812 21 0.02778 59 Genes involved in ERK/MAPK targets www.broad.mit.e...
Broad REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_COMPLEX View Gene Set 0.004427 12 0.03173 60 Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex www.broad.mit.e...
Broad REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES View Gene Set 0.004522 30 0.03188 61 Genes involved in MAPK targets/Nuclear events mediated by MAP kinases www.broad.mit.e...
Broad REACTOME_PEPTIDE_CHAIN_ELONGATION View Gene Set 0.004696 84 0.03257 62 Genes involved in Peptide chain elongation www.broad.mit.e...
Broad REACTOME_DUAL_INCISION_REACTION_IN_TC_NER View Gene Set 0.004938 28 0.0337 63 Genes involved in Dual incision reaction in TC-NER www.broad.mit.e...
Broad REACTOME_RNA_POL_II_CTD_PHOSPHORYLATION_AND_INTERACTION_WITH_CE View Gene Set 0.005166 26 0.03471 64 Genes involved in RNA Pol II CTD phosphorylation and interaction with CE www.broad.mit.e...
Broad REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE View Gene Set 0.00551 90 0.0359 65 Genes involved in Late Phase of HIV Life Cycle www.broad.mit.e...
Broad REACTOME_MAP_KINASES_ACTIVATION_IN_TLR_CASCADE View Gene Set 0.005464 44 0.0359 65 Genes involved in MAP kinases activation in TLR cascade www.broad.mit.e...
Broad REACTOME_SIGNALLING_TO_RAS View Gene Set 0.005702 26 0.0366 67 Genes involved in Signalling to RAS www.broad.mit.e...
Broad REACTOME_M_G1_TRANSITION View Gene Set 0.006556 61 0.04114 68 Genes involved in M/G1 Transition www.broad.mit.e...
Broad REACTOME_VIRAL_MRNA_TRANSLATION View Gene Set 0.006602 84 0.04114 68 Genes involved in Viral mRNA Translation www.broad.mit.e...
Broad REACTOME_UNFOLDED_PROTEIN_RESPONSE View Gene Set 0.006879 19 0.04226 70 Genes involved in Unfolded Protein Response www.broad.mit.e...
Broad REACTOME_PHOSPHORYLATION_OF_THE_APC View Gene Set 0.00737 17 0.04464 71 Genes involved in Phosphorylation of the APC/C www.broad.mit.e...
Broad REACTOME_MEMBRANE_TRAFFICKING View Gene Set 0.007561 78 0.0447 72 Genes involved in Membrane Trafficking www.broad.mit.e...
Broad REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC View Gene Set 0.007588 28 0.0447 72 Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC www.broad.mit.e...

Gene Set Collection: Broad.c3.MIR

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad ATACTGT MIR-144 View Gene Set 0.000407 173 0.04498 1 Targets of MicroRNA ATACTGT MIR-144 www.broad.mit.e... MIR-144...
Broad CCAGGGG MIR-331 View Gene Set 0.0003337 83 0.04498 1 Targets of MicroRNA CCAGGGG MIR-331 www.broad.mit.e... MIR-331...

Gene Set Collection: Broad.c3.TFT

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad SCGGAAGY_V$ELK1_02 View Gene Set 1.488e-10 784 9.151e-08 1 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SCGGAAGY which matches annotation for ELK1: ELK1 member of ETS oncogene family www.broad.mit.e...
Broad RCGCANGCGY_V$NRF1_Q6 View Gene Set 1.095e-06 580 0.0003366 2 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RCGCANGCGY which matches annotation for NRF1: nuclear respiratory factor 1 www.broad.mit.e...
Broad GGGCGGR_V$SP1_Q6 View Gene Set 8.683e-06 2120 0.00178 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGGCGGR which matches annotation for SP1: Sp1 transcription factor www.broad.mit.e...
Broad V$ELK1_02 View Gene Set 1.334e-05 170 0.001925 4 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNCCGGAARTNN which matches annotation for ELK1: ELK1 member of ETS oncogene family www.broad.mit.e...
Broad GTGACGY_V$E4F1_Q6 View Gene Set 1.565e-05 462 0.001925 4 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GTGACGY which matches annotation for E4F1: E4F transcription factor 1 www.broad.mit.e...
Broad GCCATNTTG_V$YY1_Q6 View Gene Set 2.864e-05 289 0.002936 6 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTG which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad GGAANCGGAANY_UNKNOWN View Gene Set 0.0002324 79 0.02012 7 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGAANCGGAANY. Motif does not match any known transcription factor www.broad.mit.e...
Broad TCCCRNNRTGC_UNKNOWN View Gene Set 0.0002617 130 0.02012 7 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TCCCRNNRTGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$YY1_01 View Gene Set 0.0004337 190 0.02964 9 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNCCATNTWNNNWN which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad V$YY1_Q6 View Gene Set 0.0005156 166 0.03171 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTN which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad V$NFMUE1_Q6 View Gene Set 0.0007309 175 0.04086 11 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CGGCCATCT. Motif does not match any known transcription factor www.broad.mit.e...

Gene Set Collection: Broad.c4.CGN

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad MORF_SOD1 View Gene Set 2.512e-13 247 1.072e-10 1 Neighborhood of SOD1 www.broad.mit.e...
Broad MORF_PRKAG1 View Gene Set 2.698e-12 202 5.759e-10 2 Neighborhood of PRKAG1 www.broad.mit.e...
Broad MORF_DDB1 View Gene Set 1.224e-10 220 1.742e-08 3 Neighborhood of DDB1 www.broad.mit.e...
Broad MORF_EIF3S2 View Gene Set 2.15e-10 220 2.295e-08 4 Neighborhood of EIF3S2 www.broad.mit.e...
Broad MORF_CSNK2B View Gene Set 3.39e-10 256 2.895e-08 5 Neighborhood of CSNK2B www.broad.mit.e...
Broad MORF_DAP3 View Gene Set 6.064e-09 175 4.315e-07 6 Neighborhood of DAP3 www.broad.mit.e...
Broad MORF_DEAF1 View Gene Set 7.467e-09 54 4.555e-07 7 Neighborhood of DEAF1 www.broad.mit.e...
Broad MORF_RAD23A View Gene Set 1.321e-08 316 7.051e-07 8 Neighborhood of RAD23A www.broad.mit.e...
Broad MORF_RAN View Gene Set 1.921e-08 242 9.114e-07 9 Neighborhood of RAN www.broad.mit.e...
Broad MORF_EI24 View Gene Set 4.915e-07 136 2.099e-05 10 Neighborhood of EI24 www.broad.mit.e...
Broad MORF_AP3D1 View Gene Set 1.101e-06 119 4.273e-05 11 Neighborhood of AP3D1 www.broad.mit.e...
Broad MORF_BUB3 View Gene Set 1.513e-06 256 5.041e-05 12 Neighborhood of BUB3 www.broad.mit.e...
Broad MORF_AATF View Gene Set 1.653e-06 179 5.041e-05 12 Neighborhood of AATF www.broad.mit.e...
Broad MORF_CDC16 View Gene Set 1.602e-06 67 5.041e-05 12 Neighborhood of CDC16 www.broad.mit.e...
Broad MORF_GNB1 View Gene Set 3.215e-06 276 8.58e-05 15 Neighborhood of GNB1 www.broad.mit.e...
Broad MORF_MAP2K2 View Gene Set 3.105e-06 123 8.58e-05 15 Neighborhood of MAP2K2 www.broad.mit.e...
Broad MORF_HDAC2 View Gene Set 5.04e-06 256 0.0001266 17 Neighborhood of HDAC2 www.broad.mit.e...
Broad MORF_GMPS View Gene Set 6.527e-06 48 0.0001548 18 Neighborhood of GMPS www.broad.mit.e...
Broad MORF_HDAC1 View Gene Set 7.088e-06 222 0.0001593 19 Neighborhood of HDAC1 www.broad.mit.e...
Broad MORF_FBL View Gene Set 8.09e-06 121 0.0001659 20 Neighborhood of FBL www.broad.mit.e...
Broad MORF_TPR View Gene Set 8.16e-06 131 0.0001659 20 Neighborhood of TPR www.broad.mit.e...
Broad MORF_RAD23B View Gene Set 1.002e-05 159 0.0001944 22 Neighborhood of RAD23B www.broad.mit.e...
Broad MORF_PPP1CA View Gene Set 1.437e-05 145 0.0002669 23 Neighborhood of PPP1CA www.broad.mit.e...
Broad MORF_PSMC1 View Gene Set 1.826e-05 162 0.000315 24 Neighborhood of PSMC1 www.broad.mit.e...
Broad MORF_UBE2I View Gene Set 1.844e-05 208 0.000315 24 Neighborhood of UBE2I www.broad.mit.e...
Broad MORF_ACP1 View Gene Set 2.037e-05 178 0.0003346 26 Neighborhood of ACP1 www.broad.mit.e...
Broad GNF2_NS View Gene Set 2.164e-05 35 0.0003422 27 Neighborhood of NS www.broad.mit.e...
Broad MORF_GSPT1 View Gene Set 2.329e-05 41 0.0003551 28 Neighborhood of GSPT1 www.broad.mit.e...
Broad GCM_NF2 View Gene Set 2.952e-05 235 0.0004347 29 Neighborhood of NF2 www.broad.mit.e...
Broad MORF_UBE2N View Gene Set 3.476e-05 79 0.0004948 30 Neighborhood of UBE2N www.broad.mit.e...
Broad GCM_USP6 View Gene Set 5.099e-05 54 0.0007024 31 Neighborhood of USP6 www.broad.mit.e...
Broad MORF_HAT1 View Gene Set 5.942e-05 155 0.0007929 32 Neighborhood of HAT1 www.broad.mit.e...
Broad MORF_RAD21 View Gene Set 6.389e-05 157 0.0008074 33 Neighborhood of RAD21 www.broad.mit.e...
Broad MORF_RAC1 View Gene Set 6.467e-05 196 0.0008074 33 Neighborhood of RAC1 www.broad.mit.e...
Broad GCM_BCL2L1 View Gene Set 6.618e-05 25 0.0008074 33 Neighborhood of BCL2L1 www.broad.mit.e...
Broad MORF_ERH View Gene Set 7.717e-05 103 0.0009153 36 Neighborhood of ERH www.broad.mit.e...
Broad MORF_PRKDC View Gene Set 8.734e-05 173 0.001008 37 Neighborhood of PRKDC www.broad.mit.e...
Broad MORF_PPP2R4 View Gene Set 9.278e-05 44 0.001043 38 Neighborhood of PPP2R4 www.broad.mit.e...
Broad MORF_XPC View Gene Set 0.000107 55 0.001142 39 Neighborhood of XPC www.broad.mit.e...
Broad MORF_PTPN11 View Gene Set 0.0001047 93 0.001142 39 Neighborhood of PTPN11 www.broad.mit.e...
Broad MORF_XRCC5 View Gene Set 0.0001191 210 0.001241 41 Neighborhood of XRCC5 www.broad.mit.e...
Broad MORF_NME2 View Gene Set 0.0001276 145 0.001248 42 Neighborhood of NME2 www.broad.mit.e...
Broad MORF_RAB1A View Gene Set 0.0001276 179 0.001248 42 Neighborhood of RAB1A www.broad.mit.e...
Broad MORF_SKP1A View Gene Set 0.0001286 175 0.001248 42 Neighborhood of SKP1A www.broad.mit.e...
Broad GCM_HBP1 View Gene Set 0.0001517 54 0.00144 45 Neighborhood of HBP1 www.broad.mit.e...
Broad GNF2_RAN View Gene Set 0.0001597 78 0.001482 46 Neighborhood of RAN www.broad.mit.e...
Broad MORF_PRDX3 View Gene Set 0.0002161 79 0.001963 47 Neighborhood of PRDX3 www.broad.mit.e...
Broad MORF_DEK View Gene Set 0.0002405 229 0.00214 48 Neighborhood of DEK www.broad.mit.e...
Broad MORF_ANP32B View Gene Set 0.0002619 174 0.002282 49 Neighborhood of ANP32B www.broad.mit.e...
Broad MORF_PRKAR1A View Gene Set 0.0003055 133 0.002609 50 Neighborhood of PRKAR1A www.broad.mit.e...
Broad GCM_CHUK View Gene Set 0.0003705 61 0.003102 51 Neighborhood of CHUK www.broad.mit.e...
Broad GNF2_NPM1 View Gene Set 0.0003823 57 0.003139 52 Neighborhood of NPM1 www.broad.mit.e...
Broad MORF_GPX4 View Gene Set 0.0004203 49 0.003386 53 Neighborhood of GPX4 www.broad.mit.e...
Broad GCM_ACTG1 View Gene Set 0.0004608 113 0.003644 54 Neighborhood of ACTG1 www.broad.mit.e...
Broad MORF_MTA1 View Gene Set 0.0004955 95 0.003847 55 Neighborhood of MTA1 www.broad.mit.e...
Broad MORF_BECN1 View Gene Set 0.0005393 93 0.004112 56 Neighborhood of BECN1 www.broad.mit.e...
Broad MORF_PPP2R5E View Gene Set 0.0005507 76 0.004125 57 Neighborhood of PPP2R5E www.broad.mit.e...
Broad MORF_ATOX1 View Gene Set 0.0005649 72 0.004159 58 Neighborhood of ATOX1 www.broad.mit.e...
Broad MORF_CSNK1D View Gene Set 0.0006337 65 0.004516 59 Neighborhood of CSNK1D www.broad.mit.e...
Broad GCM_BECN1 View Gene Set 0.0006345 59 0.004516 59 Neighborhood of BECN1 www.broad.mit.e...
Broad GCM_NPM1 View Gene Set 0.0006854 108 0.004798 61 Neighborhood of NPM1 www.broad.mit.e...
Broad MORF_DAP View Gene Set 0.0007555 72 0.00512 62 Neighborhood of DAP www.broad.mit.e...
Broad MORF_REV3L View Gene Set 0.0007551 52 0.00512 62 Neighborhood of REV3L www.broad.mit.e...
Broad MORF_UNG View Gene Set 0.0008161 65 0.005399 64 Neighborhood of UNG www.broad.mit.e...
Broad MORF_PHB View Gene Set 0.0008219 112 0.005399 64 Neighborhood of PHB www.broad.mit.e...
Broad MORF_PPP6C View Gene Set 0.0009815 88 0.006224 66 Neighborhood of PPP6C www.broad.mit.e...
Broad GCM_UBE2N View Gene Set 0.0009912 125 0.006224 66 Neighborhood of UBE2N www.broad.mit.e...
Broad GNF2_EIF3S6 View Gene Set 0.0009823 109 0.006224 66 Neighborhood of EIF3S6 www.broad.mit.e...
Broad GCM_SMO View Gene Set 0.00108 49 0.006682 69 Neighborhood of SMO www.broad.mit.e...
Broad GCM_DFFA View Gene Set 0.001289 100 0.007866 70 Neighborhood of DFFA www.broad.mit.e...
Broad MORF_CTBP1 View Gene Set 0.001701 149 0.01011 71 Neighborhood of CTBP1 www.broad.mit.e...
Broad GCM_TPT1 View Gene Set 0.001705 69 0.01011 71 Neighborhood of TPT1 www.broad.mit.e...
Broad MORF_G22P1 View Gene Set 0.001873 145 0.01096 73 Neighborhood of G22P1 www.broad.mit.e...
Broad MORF_AP2M1 View Gene Set 0.001978 197 0.01141 74 Neighborhood of AP2M1 www.broad.mit.e...
Broad MORF_NPM1 View Gene Set 0.002143 152 0.0122 75 Neighborhood of NPM1 www.broad.mit.e...
Broad GCM_DDX11 View Gene Set 0.002281 38 0.01281 76 Neighborhood of DDX11 www.broad.mit.e...
Broad MORF_SS18 View Gene Set 0.002491 55 0.01381 77 Neighborhood of SS18 www.broad.mit.e...
Broad MORF_MBD4 View Gene Set 0.002625 76 0.01437 78 Neighborhood of MBD4 www.broad.mit.e...
Broad MORF_PPP1CC View Gene Set 0.002709 150 0.01464 79 Neighborhood of PPP1CC www.broad.mit.e...
Broad GCM_DDX5 View Gene Set 0.002744 52 0.01464 80 Neighborhood of DDX5 www.broad.mit.e...
Broad MORF_ERCC2 View Gene Set 0.003236 91 0.01639 81 Neighborhood of ERCC2 www.broad.mit.e...
Broad MORF_PSMC2 View Gene Set 0.003191 100 0.01639 81 Neighborhood of PSMC2 www.broad.mit.e...
Broad MORF_RPA2 View Gene Set 0.003182 170 0.01639 81 Neighborhood of RPA2 www.broad.mit.e...
Broad MORF_BMI1 View Gene Set 0.003235 71 0.01639 81 Neighborhood of BMI1 www.broad.mit.e...
Broad MORF_EIF4E View Gene Set 0.003264 76 0.01639 81 Neighborhood of EIF4E www.broad.mit.e...
Broad MORF_EIF4A2 View Gene Set 0.003585 120 0.0178 86 Neighborhood of EIF4A2 www.broad.mit.e...
Broad MORF_TPT1 View Gene Set 0.004804 100 0.02358 87 Neighborhood of TPT1 www.broad.mit.e...
Broad MORF_IKBKG View Gene Set 0.00522 119 0.02533 88 Neighborhood of IKBKG www.broad.mit.e...
Broad MORF_EIF3S6 View Gene Set 0.007932 108 0.03806 89 Neighborhood of EIF3S6 www.broad.mit.e...
Broad GCM_APEX1 View Gene Set 0.008897 102 0.04221 90 Neighborhood of APEX1 www.broad.mit.e...
Broad MORF_PPP2CA View Gene Set 0.009099 110 0.0427 91 Neighborhood of PPP2CA www.broad.mit.e...
Broad MORF_RFC1 View Gene Set 0.01019 98 0.04678 92 Neighborhood of RFC1 www.broad.mit.e...
Broad GCM_MLL View Gene Set 0.01014 130 0.04678 92 Neighborhood of MLL www.broad.mit.e...

Gene Set Collection: Broad.c4.CM

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad module_83 View Gene Set 4.609e-11 296 2.093e-08 1 Genes in module_83 www.broad.mit.e...
Broad module_62 View Gene Set 1.181e-06 88 0.000268 2 Genes in module_62 www.broad.mit.e...
Broad module_28 View Gene Set 2.762e-06 32 0.0003311 3 Genes in module_28 www.broad.mit.e...
Broad module_32 View Gene Set 3.579e-06 227 0.0003311 3 Genes in module_32 www.broad.mit.e...
Broad module_91 View Gene Set 3.647e-06 37 0.0003311 3 Genes in module_91 www.broad.mit.e...
Broad module_114 View Gene Set 4.741e-06 314 0.0003587 6 Genes in module_114 www.broad.mit.e...
Broad module_4 View Gene Set 8.112e-06 21 0.0005101 7 Genes in module_4 www.broad.mit.e...
Broad module_82 View Gene Set 9.346e-06 24 0.0005101 7 Genes in module_82 www.broad.mit.e...
Broad module_133 View Gene Set 1.011e-05 15 0.0005101 7 Genes in module_133 www.broad.mit.e...
Broad module_22 View Gene Set 1.797e-05 45 0.0008157 10 Genes in module_22 www.broad.mit.e...
Broad module_151 View Gene Set 2.142e-05 297 0.0008841 11 Genes in module_151 www.broad.mit.e...
Broad module_152 View Gene Set 2.96e-05 121 0.00112 12 Genes in module_152 www.broad.mit.e...
Broad module_160 View Gene Set 5.206e-05 15 0.001818 13 Genes in module_160 www.broad.mit.e...
Broad module_239 View Gene Set 7.854e-05 112 0.002547 14 Genes in module_239 www.broad.mit.e...
Broad module_149 View Gene Set 0.0001585 36 0.004798 15 Genes in module_149 www.broad.mit.e...
Broad module_159 View Gene Set 0.0001723 81 0.004889 16 Genes in module_159 www.broad.mit.e...
Broad module_35 View Gene Set 0.0003053 16 0.008152 17 Genes in module_35 www.broad.mit.e...
Broad module_350 View Gene Set 0.0003596 57 0.00907 18 Genes in module_350 www.broad.mit.e...
Broad module_17 View Gene Set 0.0004555 351 0.01088 19 Genes in module_17 www.broad.mit.e...
Broad module_42 View Gene Set 0.0006389 25 0.0145 20 Genes in module_42 www.broad.mit.e...
Broad module_110 View Gene Set 0.0007469 15 0.01615 21 Genes in module_110 www.broad.mit.e...
Broad module_77 View Gene Set 0.0007863 28 0.01623 22 Genes in module_77 www.broad.mit.e...
Broad module_233 View Gene Set 0.001159 22 0.02287 23 Genes in module_233 www.broad.mit.e...
Broad module_50 View Gene Set 0.001286 13 0.02433 24 Genes in module_50 www.broad.mit.e...
Broad module_155 View Gene Set 0.001476 25 0.02652 25 Genes in module_155 www.broad.mit.e...
Broad module_278 View Gene Set 0.001519 34 0.02652 25 Genes in module_278 www.broad.mit.e...
Broad module_115 View Gene Set 0.001725 27 0.02901 27 Genes in module_115 www.broad.mit.e...
Broad module_81 View Gene Set 0.002426 20 0.03934 28 Genes in module_81 www.broad.mit.e...

Gene Set Collection: Broad.c5.BP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad CELLULAR_PROTEIN_METABOLIC_PROCESS View Gene Set 7.826e-08 1085 4.448e-05 1 Genes annotated by the GO term GO:0044267. The chemical reactions and pathways involving a specific protein rather than of proteins in general occurring at the level of an individual cell. Includes protein modification. www.broad.mit.e...
Broad CELLULAR_MACROMOLECULE_METABOLIC_PROCESS View Gene Set 1.078e-07 1099 4.448e-05 1 Genes annotated by the GO term GO:0044260. The chemical reactions and pathways involving macromolecules large molecules including proteins nucleic acids and carbohydrates as carried out by individual cells. www.broad.mit.e...
Broad INTRACELLULAR_TRANSPORT View Gene Set 1.789e-07 271 4.919e-05 3 Genes annotated by the GO term GO:0046907. The directed movement of substances within a cell. www.broad.mit.e...
Broad PROTEIN_METABOLIC_PROCESS View Gene Set 7.482e-07 1198 0.0001543 4 Genes annotated by the GO term GO:0019538. The chemical reactions and pathways involving a specific protein rather than of proteins in general. Includes protein modification. www.broad.mit.e...
Broad BIOSYNTHETIC_PROCESS View Gene Set 4.488e-06 459 0.0007405 5 Genes annotated by the GO term GO:0009058. The energy-requiring part of metabolism in which simpler substances are transformed into more complex ones as in growth and other biosynthetic processes. www.broad.mit.e...
Broad INTRACELLULAR_PROTEIN_TRANSPORT View Gene Set 1.682e-05 138 0.002313 6 Genes annotated by the GO term GO:0006886. The directed movement of proteins in a cell including the movement of proteins between specific compartments or structures within a cell such as organelles of a eukaryotic cell. www.broad.mit.e...
Broad TRANSLATIONAL_INITIATION View Gene Set 3.334e-05 39 0.003438 7 Genes annotated by the GO term GO:0006413. The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome mRNA and an initiation complex that contains the first aminoacyl-tRNA. www.broad.mit.e...
Broad PROTEIN_TRANSPORT View Gene Set 2.988e-05 150 0.003438 7 Genes annotated by the GO term GO:0015031. The directed movement of proteins into out of within or between cells. www.broad.mit.e...
Broad PROTEIN_CATABOLIC_PROCESS View Gene Set 3.819e-05 68 0.0035 9 Genes annotated by the GO term GO:0030163. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native active configuration with or without the hydrolysis of peptide bonds. www.broad.mit.e...
Broad CELLULAR_PROTEIN_CATABOLIC_PROCESS View Gene Set 6.657e-05 58 0.005492 10 Genes annotated by the GO term GO:0044257. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. www.broad.mit.e...
Broad CELLULAR_BIOSYNTHETIC_PROCESS View Gene Set 0.0001046 311 0.007846 11 Genes annotated by the GO term GO:0044249. The chemical reactions and pathways resulting in the formation of substances carried out by individual cells. www.broad.mit.e...
Broad ESTABLISHMENT_OF_CELLULAR_LOCALIZATION View Gene Set 0.0001274 342 0.007885 12 Genes annotated by the GO term GO:0051649. The directed movement of a substance or cellular entity such as a protein complex or organelle to a specific location within or in the membrane of a cell. www.broad.mit.e...
Broad REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0001351 124 0.007885 12 Genes annotated by the GO term GO:0051128. Any process that modulates the frequency rate or extent of the processes involved in the formation arrangement of constituent parts or disassembly of cell structures including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. www.broad.mit.e...
Broad MITOCHONDRION_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0001256 47 0.007885 12 Genes annotated by the GO term GO:0007005. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a mitochondrion; includes mitochondrial morphology and distribution and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. www.broad.mit.e...
Broad MACROMOLECULE_BIOSYNTHETIC_PROCESS View Gene Set 0.0001434 313 0.007885 12 Genes annotated by the GO term GO:0009059. The chemical reactions and pathways resulting in the formation of macromolecules large molecules including proteins nucleic acids and carbohydrates. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY View Gene Set 0.000156 74 0.008044 16 Genes annotated by the GO term GO:0022613. The cellular process by which a complex containing RNA and proteins is synthesized aggregates and bonds together. www.broad.mit.e...
Broad GOLGI_VESICLE_TRANSPORT View Gene Set 0.0001721 47 0.008229 17 Genes annotated by the GO term GO:0048193. The directed movement of substances into out of or within the Golgi apparatus mediated by vesicles. www.broad.mit.e...
Broad CELLULAR_LOCALIZATION View Gene Set 0.0001796 360 0.008229 17 Genes annotated by the GO term GO:0051641. The processes by which a substance or cellular entity such as a protein complex or organelle is transported to and/or maintained in a specific location within or in the membrane of a cell. www.broad.mit.e...
Broad BIOPOLYMER_CATABOLIC_PROCESS View Gene Set 0.0001972 115 0.008562 19 Genes annotated by the GO term GO:0043285. The chemical reactions and pathways resulting in the breakdown of biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. www.broad.mit.e...
Broad TRANSLATION View Gene Set 0.0002464 177 0.01016 20 Genes annotated by the GO term GO:0006412. The chemical reactions and pathways resulting in the formation of a protein. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. www.broad.mit.e...
Broad PROTEIN_TARGETING View Gene Set 0.0002626 103 0.01032 21 Genes annotated by the GO term GO:0006605. The process of targeting specific proteins to particular membrane-bound subcellular organelles. Usually requires an organelle specific protein sequence motif. www.broad.mit.e...
Broad PROTEOLYSIS View Gene Set 0.0002966 187 0.01112 22 Genes annotated by the GO term GO:0006508. The hydrolysis of a peptide bond or bonds within a protein. www.broad.mit.e...
Broad PROTEIN_LOCALIZATION View Gene Set 0.0004166 207 0.01494 23 Genes annotated by the GO term GO:0008104. The processes by which a protein is transported to or maintained in a specific location. www.broad.mit.e...
Broad PEROXISOME_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0005186 15 0.01723 24 Genes annotated by the GO term GO:0007031. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a peroxisome. www.broad.mit.e...
Broad PROTEIN_RNA_COMPLEX_ASSEMBLY View Gene Set 0.0005221 59 0.01723 24 Genes annotated by the GO term GO:0022618. The aggregation arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. www.broad.mit.e...
Broad ESTABLISHMENT_OF_PROTEIN_LOCALIZATION View Gene Set 0.0007364 183 0.02337 26 Genes annotated by the GO term GO:0045184. The directed movement of a protein to a specific location. www.broad.mit.e...
Broad REGULATION_OF_TRANSLATIONAL_INITIATION View Gene Set 0.0007852 31 0.02399 27 Genes annotated by the GO term GO:0006446. Any process that modulates the frequency rate or extent of translational initiation. www.broad.mit.e...
Broad PROTEIN_TARGETING_TO_MEMBRANE View Gene Set 0.0008341 11 0.02458 28 Genes annotated by the GO term GO:0006612. The process of directing proteins towards a membrane using signals contained within the protein. www.broad.mit.e...
Broad PROTEIN_TARGETING_TO_MITOCHONDRION View Gene Set 0.0008648 10 0.0246 29 Genes annotated by the GO term GO:0006626. The process of directing proteins towards and into the mitochondrion mediated by mitochondrial proteins that recognize signals contained within the imported protein. www.broad.mit.e...
Broad PROTEIN_FOLDING View Gene Set 0.001787 56 0.04914 30 Genes annotated by the GO term GO:0006457. The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. www.broad.mit.e...

Gene Set Collection: Broad.c5.CC

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad CYTOPLASMIC_PART View Gene Set 6.498e-14 1350 1.101e-11 1 Genes annotated by the GO term GO:0044444. Any constituent part of the cytoplasm all of the contents of a cell excluding the plasma membrane and nucleus but including other subcellular structures. www.broad.mit.e...
Broad MITOCHONDRION View Gene Set 9.453e-14 335 1.101e-11 1 Genes annotated by the GO term GO:0005739. A semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. www.broad.mit.e...
Broad CYTOPLASM View Gene Set 1.595e-12 2054 1.239e-10 3 Genes annotated by the GO term GO:0005737. All of the contents of a cell excluding the plasma membrane and nucleus but including other subcellular structures. www.broad.mit.e...
Broad MITOCHONDRIAL_PART View Gene Set 4.291e-11 140 2.5e-09 4 Genes annotated by the GO term GO:0044429. Any constituent part of a mitochondrion a semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. www.broad.mit.e...
Broad ORGANELLE_MEMBRANE View Gene Set 1.483e-09 290 6.911e-08 5 Genes annotated by the GO term GO:0031090. The lipid bilayer surrounding an organelle. www.broad.mit.e...
Broad MITOCHONDRIAL_MEMBRANE_PART View Gene Set 5.818e-09 52 2.259e-07 6 Genes annotated by the GO term GO:0044455. Any constituent part of the mitochondrial membrane either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. www.broad.mit.e...
Broad MITOCHONDRIAL_MEMBRANE View Gene Set 3.495e-08 85 1.07e-06 7 Genes annotated by the GO term GO:0031966. Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. www.broad.mit.e...
Broad ENVELOPE View Gene Set 4.594e-08 165 1.07e-06 7 Genes annotated by the GO term GO:0031975. A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers and may include a cell wall layer also includes the space between layers. www.broad.mit.e...
Broad ORGANELLE_ENVELOPE View Gene Set 4.594e-08 165 1.07e-06 7 Genes annotated by the GO term GO:0031967. A double membrane structure enclosing an organelle including two lipid bilayers and the region between them. In some cases an organelle envelope may have more than two membranes. www.broad.mit.e...
Broad MITOCHONDRIAL_ENVELOPE View Gene Set 4.006e-08 95 1.07e-06 7 Genes annotated by the GO term GO:0005740. The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space. www.broad.mit.e...
Broad ORGANELLE_PART View Gene Set 7.553e-08 1149 1.6e-06 11 Genes annotated by the GO term GO:0044422. Any constituent part of an organelle an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad INTRACELLULAR_ORGANELLE_PART View Gene Set 1.005e-07 1144 1.952e-06 12 Genes annotated by the GO term GO:0044446. A constituent part of an intracellular organelle an organized structure of distinctive morphology and function occurring within the cell. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad MITOCHONDRIAL_INNER_MEMBRANE View Gene Set 2.038e-06 66 3.652e-05 13 Genes annotated by the GO term GO:0005743. The inner i.e. lumen-facing lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. www.broad.mit.e...
Broad ORGANELLE_INNER_MEMBRANE View Gene Set 4.721e-06 74 7.858e-05 14 Genes annotated by the GO term GO:0019866. The inner i.e. lumen-facing lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites. www.broad.mit.e...
Broad ENDOPLASMIC_RETICULUM View Gene Set 7.947e-06 282 0.0001234 15 Genes annotated by the GO term GO:0005783. The irregular network of unit membranes visible only by electron microscopy that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels which are often expanded into slitlike cavities called cisternae. The ER takes two forms rough (or granular) with ribosomes adhering to the outer surface and smooth (with no ribosomes attached). www.broad.mit.e...
Broad ORGANELLE_LUMEN View Gene Set 1.033e-05 434 0.0001416 16 Genes annotated by the GO term GO:0043233. The volume enclosed by the membranes of a particular organelle e.g. endoplasmic reticulum lumen or the space between the two lipid bilayers of a double membrane surrounding an organelle e.g. nuclear membrane lumen. www.broad.mit.e...
Broad MEMBRANE_ENCLOSED_LUMEN View Gene Set 1.033e-05 434 0.0001416 16 Genes annotated by the GO term GO:0031974. The enclosed volume within a sealed membrane or between two sealed membranes. www.broad.mit.e...
Broad MITOCHONDRIAL_MATRIX View Gene Set 0.0001199 46 0.001397 18 Genes annotated by the GO term GO:0005759. The gel-like material with considerable fine structure that lies in the matrix space or lumen of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and in some organisms the enzymes concerned with fatty-acid oxidation. www.broad.mit.e...
Broad MITOCHONDRIAL_LUMEN View Gene Set 0.0001199 46 0.001397 18 Genes annotated by the GO term GO:0031980. The volume enclosed by the mitochondrial inner membrane. www.broad.mit.e...
Broad ER_GOLGI_INTERMEDIATE_COMPARTMENT View Gene Set 0.0001119 22 0.001397 18 Genes annotated by the GO term GO:0005793. A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex with a distinctive membrane protein composition; involved in ER-to-Golgi transport. www.broad.mit.e...
Broad NADH_DEHYDROGENASE_COMPLEX View Gene Set 0.0003784 15 0.003833 21 Genes annotated by the GO term GO:0030964. An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyses the transfer of a pair of electrons from NADH to a quinone. www.broad.mit.e...
Broad MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I View Gene Set 0.0003784 15 0.003833 21 Genes annotated by the GO term GO:0005747. A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits including NADH dehydrogenase (ubiquinone) flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III) and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. www.broad.mit.e...
Broad RESPIRATORY_CHAIN_COMPLEX_I View Gene Set 0.0003784 15 0.003833 21 Genes annotated by the GO term GO:0045271. Respiratory chain complex I is an enzyme of the respiratory chain. It consists of at least 34 polypeptide chains and is L-shaped with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex. www.broad.mit.e...
Broad NUCLEOLAR_PART View Gene Set 0.0004042 16 0.003924 24 Genes annotated by the GO term GO:0044452. Any constituent part of a nucleolus a small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. www.broad.mit.e...
Broad ORGANELLE_OUTER_MEMBRANE View Gene Set 0.0004704 24 0.004384 25 Genes annotated by the GO term GO:0031968. The outer i.e. cytoplasm-facing lipid bilayer of an organelle envelope. www.broad.mit.e...
Broad MITOCHONDRIAL_OUTER_MEMBRANE View Gene Set 0.0005343 18 0.004446 26 Genes annotated by the GO term GO:0005741. The outer i.e. cytoplasm-facing lipid bilayer of the mitochondrial envelope. www.broad.mit.e...
Broad MITOCHONDRIAL_RESPIRATORY_CHAIN View Gene Set 0.0005027 24 0.004446 26 Genes annotated by the GO term GO:0005746. The protein complexes that form the mitochondrial electron transport system (the respiratory chain). Complexes I III and IV can transport protons if embedded in an oriented membrane such as an intact mitochondrial inner membrane. www.broad.mit.e...
Broad NUCLEOLUS View Gene Set 0.00052 116 0.004446 26 Genes annotated by the GO term GO:0005730. A small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA the processing of this RNA into 5.8S 18S and 28S components of ribosomal RNA and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. www.broad.mit.e...
Broad OUTER_MEMBRANE View Gene Set 0.0005758 25 0.004626 29 Genes annotated by the GO term GO:0019867. The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. www.broad.mit.e...
Broad EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX View Gene Set 0.0007564 10 0.005875 30 Genes annotated by the GO term GO:0005852. A complex of several polypeptides that plays at least two important roles in protein synthesis: First eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. www.broad.mit.e...
Broad PROTEASOME_COMPLEX View Gene Set 0.0008915 23 0.006701 31 Genes annotated by the GO term GO:0000502. A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. www.broad.mit.e...
Broad ORGANELLAR_RIBOSOME View Gene Set 0.001577 22 0.01113 32 Genes annotated by the GO term GO:0000313. A ribosome contained within a subcellular organelle. www.broad.mit.e...
Broad MITOCHONDRIAL_RIBOSOME View Gene Set 0.001577 22 0.01113 32 Genes annotated by the GO term GO:0005761. A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. www.broad.mit.e...
Broad NUCLEAR_LUMEN View Gene Set 0.002167 365 0.01485 34 Genes annotated by the GO term GO:0031981. The volume enclosed by the nuclear inner membrane. www.broad.mit.e...
Broad OLIGOSACCHARYL_TRANSFERASE_COMPLEX View Gene Set 0.002316 9 0.01542 35 Genes annotated by the GO term GO:0008250. A multisubunit protein complex in the endoplasmic reticulum membrane of eukaryotes that transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins; includes at least nine different subunits at least in yeast. www.broad.mit.e...
Broad NUCLEAR_PART View Gene Set 0.002882 543 0.01767 36 Genes annotated by the GO term GO:0044428. Any constituent part of the nucleus a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX View Gene Set 0.002882 914 0.01767 36 Genes annotated by the GO term GO:0032991. A stable assembly of two or more macromolecules i.e. proteins nucleic acids carbohydrates or lipids in which the constituent parts function together. www.broad.mit.e...
Broad ENDOPLASMIC_RETICULUM_PART View Gene Set 0.002782 93 0.01767 36 Genes annotated by the GO term GO:0044432. Any constituent part of the endoplasmic reticulum the irregular network of unit membranes visible only by electron microscopy that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels which are often expanded into slitlike cavities called cisternae. www.broad.mit.e...
Broad GOLGI_APPARATUS View Gene Set 0.003236 222 0.01933 39 Genes annotated by the GO term GO:0005794. A compound membranous cytoplasmic organelle of eukaryotic cells consisting of flattened ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle while in invertebrates and plants where they are known usually as dictyosomes there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis in the vicinity of the cis face trans in the vicinity of the trans face and medial lying between the cis and trans regions. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX View Gene Set 0.003659 129 0.02087 40 Genes annotated by the GO term GO:0030529. A macromolecular complex containing both protein and RNA molecules. www.broad.mit.e...
Broad ENDOMEMBRANE_SYSTEM View Gene Set 0.003673 213 0.02087 40 Genes annotated by the GO term GO:0012505. A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum Golgi bodies vesicles cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. www.broad.mit.e...
Broad ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.004262 11 0.02257 42 Genes annotated by the GO term GO:0000314. The smaller of the two subunits of an organellar ribosome. www.broad.mit.e...
Broad MITOCHONDRIAL_SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.004262 11 0.02257 42 Genes annotated by the GO term GO:0005763. The smaller of the two subunits of a mitochondrial ribosome. www.broad.mit.e...
Broad SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.004262 11 0.02257 42 Genes annotated by the GO term GO:0015935. The smaller of the two subunits of a ribosome. www.broad.mit.e...
Broad PEROXISOMAL_MEMBRANE View Gene Set 0.004697 12 0.02328 45 Genes annotated by the GO term GO:0005778. The lipid bilayer surrounding a peroxisome. www.broad.mit.e...
Broad MICROBODY_MEMBRANE View Gene Set 0.004697 12 0.02328 45 Genes annotated by the GO term GO:0031903. The lipid bilayer surrounding a microbody. www.broad.mit.e...
Broad RIBOSOMAL_SUBUNIT View Gene Set 0.004599 20 0.02328 45 Genes annotated by the GO term GO:0033279. Either of the two ribonucleoprotein complexes that associate to form a ribosome. www.broad.mit.e...
Broad NUCLEAR_SPECK View Gene Set 0.005783 10 0.02807 48 Genes annotated by the GO term GO:0016607. A discrete extra-nucleolar subnuclear domain 20-50 in number in which splicing factors are seen to be localized by immunofluorescence microscopy. www.broad.mit.e...
Broad NUCLEAR_ENVELOPE_ENDOPLASMIC_RETICULUM_NETWORK View Gene Set 0.006984 91 0.03321 49 Genes annotated by the GO term GO:0042175. The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum. www.broad.mit.e...
Broad MICROTUBULE View Gene Set 0.009937 31 0.0454 50 Genes annotated by the GO term GO:0005874. Any of the long generally straight hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation e.g. in the spindle. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE View Gene Set 0.009751 48 0.0454 50 Genes annotated by the GO term GO:0031965. Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. www.broad.mit.e...

Gene Set Collection: Broad.c5.MF

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad TRANSLATION_INITIATION_FACTOR_ACTIVITY View Gene Set 4.158e-05 24 0.01646 1 Genes annotated by the GO term GO:0003743. Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. www.broad.mit.e...
Broad LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS View Gene Set 0.0002365 14 0.04682 2 Genes annotated by the GO term GO:0016875. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. www.broad.mit.e...
Broad TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING View Gene Set 0.0003726 39 0.04919 3 Genes annotated by the GO term GO:0008135. Functions during translation by binding nucleic acids during polypeptide synthesis at the ribosome. www.broad.mit.e...

Gene Set Collection: PMID

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
PMID 12429849 View Gene Set 6.752e-13 106 1.693e-09 1 Functional proteomic analysis of human nucleolus. www.ncbi.nlm.ni...
PMID 11790298 View Gene Set 2.486e-09 208 2.077e-06 2 Directed proteomic analysis of the human nucleolus. www.ncbi.nlm.ni...
PMID 12706105 View Gene Set 1.737e-09 182 2.077e-06 2 Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. www.ncbi.nlm.ni...
PMID 15029244 View Gene Set 1.507e-08 57 9.442e-06 4 Mammalian Cdh1/Fzr mediates its own degradation. www.ncbi.nlm.ni...
PMID 11543634 View Gene Set 3.086e-08 58 1.547e-05 5 The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. www.ncbi.nlm.ni...
PMID 15635413 View Gene Set 6.94e-08 421 2.9e-05 6 Nucleolar proteome dynamics. www.ncbi.nlm.ni...
PMID 17643375 View Gene Set 9.117e-08 391 3.265e-05 7 Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. www.ncbi.nlm.ni...
PMID 17220478 View Gene Set 7.735e-07 63 0.0002424 8 Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells. www.ncbi.nlm.ni...
PMID 10893419 View Gene Set 1.766e-06 41 0.0003163 9 Degradation of HIV-1 integrase by the N-end rule pathway. www.ncbi.nlm.ni...
PMID 11337588 View Gene Set 1.478e-06 17 0.0003163 9 Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. www.ncbi.nlm.ni...
PMID 12419264 View Gene Set 1.766e-06 41 0.0003163 9 The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing. www.ncbi.nlm.ni...
PMID 14550573 View Gene Set 1.766e-06 41 0.0003163 9 Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits. www.ncbi.nlm.ni...
PMID 14564014 View Gene Set 1.183e-06 47 0.0003163 9 Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. www.ncbi.nlm.ni...
PMID 9079628 View Gene Set 1.766e-06 41 0.0003163 9 HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation. www.ncbi.nlm.ni...
PMID 11279123 View Gene Set 2.052e-06 31 0.000343 15 The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 10810093 View Gene Set 3.147e-06 151 0.000358 16 Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. www.ncbi.nlm.ni...
PMID 12719574 View Gene Set 3.57e-06 42 0.000358 16 Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions. www.ncbi.nlm.ni...
PMID 12750511 View Gene Set 3.57e-06 42 0.000358 16 Hypermutation of HIV-1 DNA in the absence of the Vif protein. www.ncbi.nlm.ni...
PMID 12830140 View Gene Set 3.57e-06 42 0.000358 16 DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses. www.ncbi.nlm.ni...
PMID 12840737 View Gene Set 3.57e-06 42 0.000358 16 Good to CU. www.ncbi.nlm.ni...
PMID 12914693 View Gene Set 3.57e-06 42 0.000358 16 Death by deamination: a novel host restriction system for HIV-1. www.ncbi.nlm.ni...
PMID 12920286 View Gene Set 3.57e-06 42 0.000358 16 Virology. Weapons of mutational destruction. www.ncbi.nlm.ni...
PMID 14614829 View Gene Set 3.57e-06 42 0.000358 16 The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G. www.ncbi.nlm.ni...
PMID 9811770 View Gene Set 3.57e-06 42 0.000358 16 An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein. www.ncbi.nlm.ni...
PMID 9846577 View Gene Set 3.57e-06 42 0.000358 16 Evidence for a newly discovered cellular anti-HIV-1 phenotype. www.ncbi.nlm.ni...
PMID 12167863 View Gene Set 5.232e-06 43 0.0003858 26 Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. www.ncbi.nlm.ni...
PMID 12808465 View Gene Set 5.232e-06 43 0.0003858 26 The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. www.ncbi.nlm.ni...
PMID 12808466 View Gene Set 5.232e-06 43 0.0003858 26 Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. www.ncbi.nlm.ni...
PMID 12809610 View Gene Set 5.232e-06 43 0.0003858 26 DNA deamination mediates innate immunity to retroviral infection. www.ncbi.nlm.ni...
PMID 12970355 View Gene Set 5.232e-06 43 0.0003858 26 The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity. www.ncbi.nlm.ni...
PMID 14527406 View Gene Set 5.232e-06 43 0.0003858 26 HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. www.ncbi.nlm.ni...
PMID 14528300 View Gene Set 5.232e-06 43 0.0003858 26 The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. www.ncbi.nlm.ni...
PMID 14528301 View Gene Set 5.232e-06 43 0.0003858 26 HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. www.ncbi.nlm.ni...
PMID 14557625 View Gene Set 5.232e-06 43 0.0003858 26 The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15) a cellular inhibitor of virus infectivity. www.ncbi.nlm.ni...
PMID 11285280 View Gene Set 6.636e-06 62 0.0004753 35 Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. www.ncbi.nlm.ni...
PMID 11031247 View Gene Set 8.242e-06 51 0.000574 36 Secretory protein trafficking and organelle dynamics in living cells. www.ncbi.nlm.ni...
PMID 12481031 View Gene Set 1.015e-05 21 0.0006877 37 CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex. www.ncbi.nlm.ni...
PMID 15231748 View Gene Set 1.053e-05 519 0.0006948 38 Functional proteomics mapping of a human signaling pathway. www.ncbi.nlm.ni...
PMID 15461802 View Gene Set 1.532e-05 293 0.0009849 39 A genome annotation-driven approach to cloning the human ORFeome. www.ncbi.nlm.ni...
PMID 12791267 View Gene Set 1.59e-05 50 0.0009879 40 Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. www.ncbi.nlm.ni...
PMID 19064571 View Gene Set 1.616e-05 75 0.0009879 40 Polymorphisms in mitochondrial genes and prostate cancer risk. www.ncbi.nlm.ni...
PMID 11042152 View Gene Set 2.884e-05 315 0.001722 42 Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. www.ncbi.nlm.ni...
PMID 12859895 View Gene Set 3.012e-05 47 0.001756 43 Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. www.ncbi.nlm.ni...
PMID 12588972 View Gene Set 3.481e-05 56 0.001984 44 Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region. www.ncbi.nlm.ni...
PMID 12665801 View Gene Set 3.635e-05 261 0.002025 45 Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. www.ncbi.nlm.ni...
PMID 8811196 View Gene Set 4.383e-05 37 0.002389 46 Structure and functions of the 20S and 26S proteasomes. www.ncbi.nlm.ni...
PMID 9151826 View Gene Set 4.515e-05 14 0.002408 47 The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix. www.ncbi.nlm.ni...
PMID 12676794 View Gene Set 6.718e-05 33 0.003437 48 The RNA polymerase II elongation complex. www.ncbi.nlm.ni...
PMID 14667819 View Gene Set 6.652e-05 112 0.003437 48 Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. www.ncbi.nlm.ni...
PMID 12611891 View Gene Set 7.622e-05 40 0.003822 50 The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. www.ncbi.nlm.ni...
PMID 9878551 View Gene Set 8.038e-05 34 0.003951 51 cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. www.ncbi.nlm.ni...
PMID 15644312 View Gene Set 0.0001079 10 0.005105 52 Dissection of the mitochondrial import and assembly pathway for human Tom40. www.ncbi.nlm.ni...
PMID 18063578 View Gene Set 0.0001066 31 0.005105 52 The layered structure of human mitochondrial DNA nucleoids. www.ncbi.nlm.ni...
PMID 14743216 View Gene Set 0.0001572 132 0.007251 54 A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. www.ncbi.nlm.ni...
PMID 15308636 View Gene Set 0.0001591 25 0.007251 54 Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32 a new cycling protein that interacts with human Erv46. www.ncbi.nlm.ni...
PMID 10591208 View Gene Set 0.0001838 299 0.008226 56 The DNA sequence of human chromosome 22. www.ncbi.nlm.ni...
PMID 17588522 View Gene Set 0.0001871 14 0.008231 57 E3-independent monoubiquitination of ubiquitin-binding proteins. www.ncbi.nlm.ni...
PMID 11252894 View Gene Set 0.0002086 44 0.008716 58 Three ways to make a vesicle. www.ncbi.nlm.ni...
PMID 16806233 View Gene Set 0.0002078 66 0.008716 58 Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects. www.ncbi.nlm.ni...
PMID 19450687 View Gene Set 0.0002086 11 0.008716 58 High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes. www.ncbi.nlm.ni...
PMID 10230407 View Gene Set 0.0002434 12 0.01 61 ROC1 a homolog of APC11 represents a family of cullin partners with an associated ubiquitin ligase activity. www.ncbi.nlm.ni...
PMID 15592455 View Gene Set 0.0002538 317 0.01026 62 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. www.ncbi.nlm.ni...
PMID 15302935 View Gene Set 0.0002592 773 0.01031 63 Large-scale characterization of HeLa cell nuclear phosphoproteins. www.ncbi.nlm.ni...
PMID 19549727 View Gene Set 0.0002741 10 0.01074 64 Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. www.ncbi.nlm.ni...
PMID 10500174 View Gene Set 0.0003028 10 0.01168 65 Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons. www.ncbi.nlm.ni...
PMID 12609982 View Gene Set 0.0003142 11 0.01176 66 TIP120A associates with cullins and modulates ubiquitin ligase activity. www.ncbi.nlm.ni...
PMID 18660489 View Gene Set 0.0003098 250 0.01176 66 Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. www.ncbi.nlm.ni...
PMID 11500364 View Gene Set 0.0004043 11 0.01467 68 Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. www.ncbi.nlm.ni...
PMID 16956762 View Gene Set 0.0004096 10 0.01467 68 Insights into COPI coat assembly and function in living cells. www.ncbi.nlm.ni...
PMID 19183483 View Gene Set 0.0004021 17 0.01467 68 Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort. www.ncbi.nlm.ni...
PMID 9222609 View Gene Set 0.0004469 10 0.01578 71 A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor Fes tyrosine kinase heat shock transcription factor Hsf1 and the aryl hydrocarbon receptor. www.ncbi.nlm.ni...
PMID 9674425 View Gene Set 0.0004978 11 0.01733 72 Histone-like TAFs within the PCAF histone acetylase complex. www.ncbi.nlm.ni...
PMID 10617616 View Gene Set 0.0005196 25 0.01785 73 Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription. www.ncbi.nlm.ni...
PMID 16501559 View Gene Set 0.0005729 12 0.01941 74 Analysis of the human protein interactome and comparison with yeast worm and fly interaction datasets. www.ncbi.nlm.ni...
PMID 11124703 View Gene Set 0.0006484 18 0.02167 75 Characterization of 16 novel human genes showing high similarity to yeast sequences. www.ncbi.nlm.ni...
PMID 8849451 View Gene Set 0.0006697 46 0.02209 76 Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat. www.ncbi.nlm.ni...
PMID 15189447 View Gene Set 0.000704 11 0.02263 77 Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones. www.ncbi.nlm.ni...
PMID 17168834 View Gene Set 0.0006997 18 0.02263 77 Will diverse Tat interactions lead to novel antiretroviral drug targets? www.ncbi.nlm.ni...
PMID 10922056 View Gene Set 0.0007593 12 0.02332 79 The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex. www.ncbi.nlm.ni...
PMID 11080476 View Gene Set 0.0007966 87 0.02332 79 Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. www.ncbi.nlm.ni...
PMID 11714285 View Gene Set 0.0008187 11 0.02332 79 The appended C-domain of human methionyl-tRNA synthetase has a tRNA-sequestering function. www.ncbi.nlm.ni...
PMID 12956947 View Gene Set 0.0007582 15 0.02332 79 TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. www.ncbi.nlm.ni...
PMID 16055448 View Gene Set 0.0008187 11 0.02332 79 The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex. www.ncbi.nlm.ni...
PMID 8052601 View Gene Set 0.0008187 11 0.02332 79 Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit. www.ncbi.nlm.ni...
PMID 8078941 View Gene Set 0.0008187 11 0.02332 79 Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer. www.ncbi.nlm.ni...
PMID 8188258 View Gene Set 0.0008187 11 0.02332 79 The human EPRS locus (formerly the QARS locus): a gene encoding a class I and a class II aminoacyl-tRNA synthetase. www.ncbi.nlm.ni...
PMID 8449960 View Gene Set 0.0008187 11 0.02332 79 Expression of human aspartyl-tRNA synthetase in Escherichia coli. Functional analysis of the N-terminal putative amphiphilic helix. www.ncbi.nlm.ni...
PMID 9278442 View Gene Set 0.0008187 11 0.02332 79 Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant. www.ncbi.nlm.ni...
PMID 11829477 View Gene Set 0.0008712 13 0.02454 89 Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex. www.ncbi.nlm.ni...
PMID 18715871 View Gene Set 0.0009358 20 0.02493 90 PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4. www.ncbi.nlm.ni...
PMID 1939271 View Gene Set 0.0009357 39 0.02493 90 Abortive initiation is increased only for the weakest members of a set of down mutants of the adenovirus 2 major late promoter. www.ncbi.nlm.ni...
PMID 2449431 View Gene Set 0.0009357 39 0.02493 90 ATP activates transcription initiation from promoters by RNA polymerase II in a reversible step prior to RNA synthesis. www.ncbi.nlm.ni...
PMID 8946909 View Gene Set 0.0009357 39 0.02493 90 The general transcription factors of RNA polymerase II. www.ncbi.nlm.ni...
PMID 9405375 View Gene Set 0.0009357 39 0.02493 90 Three transitions in the RNA polymerase II transcription complex during initiation. www.ncbi.nlm.ni...
PMID 9878398 View Gene Set 0.0009446 13 0.02493 90 Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. www.ncbi.nlm.ni...
PMID 12522145 View Gene Set 0.001041 19 0.02718 96 Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif. www.ncbi.nlm.ni...
PMID 10548110 View Gene Set 0.001086 16 0.02728 97 Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex. www.ncbi.nlm.ni...
PMID 11340163 View Gene Set 0.001086 16 0.02728 97 A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression. www.ncbi.nlm.ni...
PMID 11551941 View Gene Set 0.001111 26 0.02728 97 The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 12732143 View Gene Set 0.001087 14 0.02728 97 The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. www.ncbi.nlm.ni...
PMID 8934526 View Gene Set 0.001104 25 0.02728 97 Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain. www.ncbi.nlm.ni...
PMID 9150948 View Gene Set 0.001088 15 0.02728 97 A two-dimensional gel database of human colon carcinoma proteins. www.ncbi.nlm.ni...
PMID 9852112 View Gene Set 0.001121 20 0.02728 97 Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes. www.ncbi.nlm.ni...
PMID 11402041 View Gene Set 0.001268 16 0.03057 104 Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28 S small subunit. www.ncbi.nlm.ni...
PMID 12628923 View Gene Set 0.001312 12 0.03133 105 Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome. www.ncbi.nlm.ni...
PMID 14657027 View Gene Set 0.001347 74 0.03186 106 Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. www.ncbi.nlm.ni...
PMID 11438723 View Gene Set 0.001509 10 0.03535 107 Visualization of biochemical networks in living cells. www.ncbi.nlm.ni...
PMID 9763677 View Gene Set 0.001683 15 0.03906 108 Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. www.ncbi.nlm.ni...
PMID 16713569 View Gene Set 0.001711 570 0.03935 109 A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. www.ncbi.nlm.ni...
PMID 16097034 View Gene Set 0.001828 36 0.04114 110 Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC. www.ncbi.nlm.ni...
PMID 17322308 View Gene Set 0.001838 13 0.04114 110 Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry. www.ncbi.nlm.ni...
PMID 18599441 View Gene Set 0.001838 13 0.04114 110 Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3. www.ncbi.nlm.ni...
PMID 11113628 View Gene Set 0.001914 11 0.04245 113 Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation. www.ncbi.nlm.ni...
PMID 15189156 View Gene Set 0.001985 88 0.04365 114 The molecular mechanics of eukaryotic translation. www.ncbi.nlm.ni...
PMID 10713718 View Gene Set 0.002069 10 0.0451 115 The HIV-1 vpr protein induces anoikis-resistance by modulating cell adhesion process and microfilament system assembly. www.ncbi.nlm.ni...
PMID 12535645 View Gene Set 0.002094 11 0.04526 116 Structural determinants of Rab and Rab Escort Protein interaction: Rab family motifs define a conserved binding surface. www.ncbi.nlm.ni...
PMID 9822659 View Gene Set 0.002161 11 0.0463 117 Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3. www.ncbi.nlm.ni...
PMID 14519125 View Gene Set 0.002302 12 0.04891 118 Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3. www.ncbi.nlm.ni...

Gene Set Collection: ChromosomalTiles5Mb

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null chr22_47.5-52.5Mb View Gene Set 2.85e-05 21 0.03175 1 Genomic tile: chr22 ; 47500001-52500001 Mb genome.ucsc.edu...
Null chr11_62.5-67.5Mb View Gene Set 0.0001103 119 0.03414 2 Genomic tile: chr11 ; 62500001-67500001 Mb genome.ucsc.edu...
Null chr22_45-50Mb View Gene Set 9.293e-05 26 0.03414 2 Genomic tile: chr22 ; 45000001-50000001 Mb genome.ucsc.edu...
Null chrX_115-120Mb View Gene Set 0.0001226 23 0.03414 2 Genomic tile: chrX ; 115000001-120000001 Mb genome.ucsc.edu...

Gene Set Collection: Prosite

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null PS50293 View Gene Set 3.55e-07 134 0.0002609 1 TPR_REGION expasy.org/pros...
Null PS50005 View Gene Set 8.881e-07 114 0.0003264 2 TPR expasy.org/pros...
Null PS50127 View Gene Set 1.658e-06 41 0.0004061 3 UBIQUITIN_CONJUGAT_2 expasy.org/pros...
Null PS00183 View Gene Set 3.001e-06 25 0.0005514 4 UBIQUITIN_CONJUGAT_1 expasy.org/pros...
Null PS50862 View Gene Set 2.807e-05 18 0.004126 5 AA_TRNA_LIGASE_II expasy.org/pros...
Null PS01132 View Gene Set 0.0001945 21 0.02382 6 ACTINS_ACT_LIKE expasy.org/pros...
Null PS50069 View Gene Set 0.0002839 10 0.02981 7 CULLIN_2 expasy.org/pros...
Null PS50330 View Gene Set 0.0003875 22 0.0356 8 UIM expasy.org/pros...
Null PS50866 View Gene Set 0.0005358 19 0.04375 9 GOLD expasy.org/pros...
Null PS50961 View Gene Set 0.0006126 8 0.04502 10 HTH_LA expasy.org/pros...

Gene Set Collection: Enzyme

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null EC:6.3.2.19 View Gene Set 7.937e-06 79 0.001254 1 Ubiquitin--protein ligase expasy.org/enzy...
Null EC:1.6.5.3 View Gene Set 9.847e-05 43 0.005186 2 NADH dehydrogenase (ubiquinone) expasy.org/enzy...
Null EC:1.6.99.3 View Gene Set 9.847e-05 35 0.005186 2 NADH dehydrogenase expasy.org/enzy...
Null EC:3.1.3.16 View Gene Set 0.0003339 24 0.01319 4 Phosphoprotein phosphatase expasy.org/enzy...
Null EC:1.10.2.2 View Gene Set 0.001547 13 0.04889 5 Ubiquinol--cytochrome-c reductase expasy.org/enzy...

Gene Set Collection: ppi.BIND

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.PEX19 View Gene Set 0.0001244 7 0.0235 1 Protein-protein-interaction for PEX19 www.ncbi.nlm.ni...

Gene Set Collection: ppi.BioGRID

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.G3BP1 View Gene Set 1.516e-05 18 0.00381 1 Protein-protein-interaction for G3BP1 www.ncbi.nlm.ni...
Null ppi.BIRC8 View Gene Set 8.977e-06 12 0.00381 1 Protein-protein-interaction for BIRC8 www.ncbi.nlm.ni...
Null ppi.ZNRF4 View Gene Set 1.13e-05 10 0.00381 1 Protein-protein-interaction for ZNRF4 www.ncbi.nlm.ni...
Null ppi.RNF167 View Gene Set 1.063e-05 8 0.00381 1 Protein-protein-interaction for RNF167 www.ncbi.nlm.ni...
Null ppi.RNF114 View Gene Set 1.825e-05 13 0.00381 1 Protein-protein-interaction for RNF114 www.ncbi.nlm.ni...
Null ppi.TRIM39 View Gene Set 3.903e-06 15 0.00381 1 Protein-protein-interaction for TRIM39 www.ncbi.nlm.ni...
Null ppi.DDA1 View Gene Set 8.487e-06 44 0.00381 1 Protein-protein-interaction for DDA1 www.ncbi.nlm.ni...
Null ppi.ZNRF1 View Gene Set 1.824e-05 12 0.00381 1 Protein-protein-interaction for ZNRF1 www.ncbi.nlm.ni...
Null ppi.CADPS2 View Gene Set 1.324e-05 9 0.00381 1 Protein-protein-interaction for CADPS2 www.ncbi.nlm.ni...
Null ppi.DZIP3 View Gene Set 1.791e-05 18 0.00381 1 Protein-protein-interaction for DZIP3 www.ncbi.nlm.ni...
Null ppi.PSMD6 View Gene Set 6.406e-06 21 0.00381 1 Protein-protein-interaction for PSMD6 www.ncbi.nlm.ni...
Null ppi.DTX3 View Gene Set 4.239e-05 15 0.00691 12 Protein-protein-interaction for DTX3 www.ncbi.nlm.ni...
Null ppi.RNF165 View Gene Set 4.137e-05 9 0.00691 12 Protein-protein-interaction for RNF165 www.ncbi.nlm.ni...
Null ppi.UCHL5 View Gene Set 4.512e-05 33 0.00691 12 Protein-protein-interaction for UCHL5 www.ncbi.nlm.ni...
Null ppi.THAP1 View Gene Set 4.235e-05 11 0.00691 12 Protein-protein-interaction for THAP1 www.ncbi.nlm.ni...
Null ppi.UBOX5 View Gene Set 5.939e-05 11 0.008526 16 Protein-protein-interaction for UBOX5 www.ncbi.nlm.ni...
Null ppi.PSMD13 View Gene Set 6.802e-05 20 0.00919 17 Protein-protein-interaction for PSMD13 www.ncbi.nlm.ni...
Null ppi.RNF166 View Gene Set 7.516e-05 11 0.009592 18 Protein-protein-interaction for RNF166 www.ncbi.nlm.ni...
Null ppi.DTX3L View Gene Set 9.782e-05 16 0.009769 19 Protein-protein-interaction for DTX3L www.ncbi.nlm.ni...
Null ppi.GIGYF2 View Gene Set 9.254e-05 17 0.009769 19 Protein-protein-interaction for GIGYF2 www.ncbi.nlm.ni...
Null ppi.COPS4 View Gene Set 8.651e-05 12 0.009769 19 Protein-protein-interaction for COPS4 www.ncbi.nlm.ni...
Null ppi.RNF181 View Gene Set 9.458e-05 7 0.009769 19 Protein-protein-interaction for RNF181 www.ncbi.nlm.ni...
Null ppi.RNF14 View Gene Set 9.47e-05 9 0.009769 19 Protein-protein-interaction for RNF14 www.ncbi.nlm.ni...
Null ppi.PEX19 View Gene Set 0.0001244 7 0.01143 24 Protein-protein-interaction for PEX19 www.ncbi.nlm.ni...
Null ppi.TLN1 View Gene Set 0.0001205 11 0.01143 24 Protein-protein-interaction for TLN1 www.ncbi.nlm.ni...
Null ppi.LYAR View Gene Set 0.0001368 26 0.01209 26 Protein-protein-interaction for LYAR www.ncbi.nlm.ni...
Null ppi.TRIM5 View Gene Set 0.0001835 14 0.01561 27 Protein-protein-interaction for TRIM5 www.ncbi.nlm.ni...
Null ppi.RNF185 View Gene Set 0.0002066 13 0.01694 28 Protein-protein-interaction for RNF185 www.ncbi.nlm.ni...
Null ppi.RNF130 View Gene Set 0.0002574 9 0.02039 29 Protein-protein-interaction for RNF130 www.ncbi.nlm.ni...
Null ppi.RMND5B View Gene Set 0.0003076 8 0.02356 30 Protein-protein-interaction for RMND5B www.ncbi.nlm.ni...
Null ppi.USP49 View Gene Set 0.0003186 24 0.0236 31 Protein-protein-interaction for USP49 www.ncbi.nlm.ni...
Null ppi.TRIM2 View Gene Set 0.000339 9 0.02433 32 Protein-protein-interaction for TRIM2 www.ncbi.nlm.ni...
Null ppi.PSMD14 View Gene Set 0.0003613 16 0.02441 33 Protein-protein-interaction for PSMD14 www.ncbi.nlm.ni...
Null ppi.USP14 View Gene Set 0.0003548 22 0.02441 33 Protein-protein-interaction for USP14 www.ncbi.nlm.ni...
Null ppi.TRIM43 View Gene Set 0.0003784 7 0.02484 35 Protein-protein-interaction for TRIM43 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 0.0004144 147 0.02573 36 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.RPS6KA5 View Gene Set 0.0004069 7 0.02573 36 Protein-protein-interaction for RPS6KA5 www.ncbi.nlm.ni...
Null ppi.PAAF1 View Gene Set 0.0004375 20 0.02645 38 Protein-protein-interaction for PAAF1 www.ncbi.nlm.ni...
Null ppi.LRSAM1 View Gene Set 0.000456 18 0.02686 39 Protein-protein-interaction for LRSAM1 www.ncbi.nlm.ni...
Null ppi.SRRM2 View Gene Set 0.0004757 101 0.02732 40 Protein-protein-interaction for SRRM2 www.ncbi.nlm.ni...
Null ppi.ANAPC4 View Gene Set 0.0005139 8 0.02879 41 Protein-protein-interaction for ANAPC4 www.ncbi.nlm.ni...
Null ppi.APC2 View Gene Set 0.0005478 8 0.02927 42 Protein-protein-interaction for APC2 www.ncbi.nlm.ni...
Null ppi.MKRN3 View Gene Set 0.000548 14 0.02927 42 Protein-protein-interaction for MKRN3 www.ncbi.nlm.ni...
Null ppi.TNKS View Gene Set 0.0005789 6 0.03022 44 Protein-protein-interaction for TNKS www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 0.0006166 43 0.03148 45 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.PEX5 View Gene Set 0.0006825 9 0.03408 46 Protein-protein-interaction for PEX5 www.ncbi.nlm.ni...
Null ppi.SUN2 View Gene Set 0.0008548 6 0.04177 47 Protein-protein-interaction for SUN2 www.ncbi.nlm.ni...
Null ppi.TRIM35 View Gene Set 0.0009257 6 0.04179 48 Protein-protein-interaction for TRIM35 www.ncbi.nlm.ni...
Null ppi.RPAP1 View Gene Set 0.0009544 24 0.04179 48 Protein-protein-interaction for RPAP1 www.ncbi.nlm.ni...
Null ppi.FBXW2 View Gene Set 0.0008991 7 0.04179 48 Protein-protein-interaction for FBXW2 www.ncbi.nlm.ni...
Null ppi.RAB6A View Gene Set 0.0009034 8 0.04179 48 Protein-protein-interaction for RAB6A www.ncbi.nlm.ni...
Null ppi.DCAF11 View Gene Set 0.0009393 8 0.04179 48 Protein-protein-interaction for DCAF11 www.ncbi.nlm.ni...
Null ppi.RNF7 View Gene Set 0.0009642 9 0.04179 48 Protein-protein-interaction for RNF7 www.ncbi.nlm.ni...
Null ppi.UBA5 View Gene Set 0.0009886 35 0.04205 54 Protein-protein-interaction for UBA5 www.ncbi.nlm.ni...
Null ppi.RPAP3 View Gene Set 0.00106 29 0.04427 55 Protein-protein-interaction for RPAP3 www.ncbi.nlm.ni...
Null ppi.RNF126 View Gene Set 0.001203 7 0.04936 56 Protein-protein-interaction for RNF126 www.ncbi.nlm.ni...

Gene Set Collection: ppi.anyDB

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.BIRC8 View Gene Set 8.977e-06 12 0.005802 1 Protein-protein-interaction for BIRC8 www.ncbi.nlm.ni...
Null ppi.ZNRF4 View Gene Set 1.13e-05 10 0.005802 1 Protein-protein-interaction for ZNRF4 www.ncbi.nlm.ni...
Null ppi.UBOX5 View Gene Set 4.59e-06 13 0.005802 1 Protein-protein-interaction for UBOX5 www.ncbi.nlm.ni...
Null ppi.RNF167 View Gene Set 1.063e-05 8 0.005802 1 Protein-protein-interaction for RNF167 www.ncbi.nlm.ni...
Null ppi.TRIM39 View Gene Set 5.276e-06 16 0.005802 1 Protein-protein-interaction for TRIM39 www.ncbi.nlm.ni...
Null ppi.DDA1 View Gene Set 8.487e-06 44 0.005802 1 Protein-protein-interaction for DDA1 www.ncbi.nlm.ni...
Null ppi.DZIP3 View Gene Set 9.526e-06 20 0.005802 1 Protein-protein-interaction for DZIP3 www.ncbi.nlm.ni...
Null ppi.THAP1 View Gene Set 1.942e-05 12 0.006347 8 Protein-protein-interaction for THAP1 www.ncbi.nlm.ni...
Null ppi.RNF114 View Gene Set 1.825e-05 13 0.006347 8 Protein-protein-interaction for RNF114 www.ncbi.nlm.ni...
Null ppi.ZNRF1 View Gene Set 1.824e-05 12 0.006347 8 Protein-protein-interaction for ZNRF1 www.ncbi.nlm.ni...
Null ppi.PSMD6 View Gene Set 1.578e-05 23 0.006347 8 Protein-protein-interaction for PSMD6 www.ncbi.nlm.ni...
Null ppi.NDRG1 View Gene Set 2.509e-05 58 0.007514 12 Protein-protein-interaction for NDRG1 www.ncbi.nlm.ni...
Null ppi.GIGYF2 View Gene Set 3.645e-05 19 0.009383 13 Protein-protein-interaction for GIGYF2 www.ncbi.nlm.ni...
Null ppi.RNF165 View Gene Set 4.137e-05 9 0.009383 13 Protein-protein-interaction for RNF165 www.ncbi.nlm.ni...
Null ppi.COPS4 View Gene Set 4.177e-05 17 0.009383 13 Protein-protein-interaction for COPS4 www.ncbi.nlm.ni...
Null ppi.UCHL5 View Gene Set 3.902e-05 34 0.009383 13 Protein-protein-interaction for UCHL5 www.ncbi.nlm.ni...
Null ppi.PSMD13 View Gene Set 6.802e-05 20 0.01398 17 Protein-protein-interaction for PSMD13 www.ncbi.nlm.ni...
Null ppi.PDHX View Gene Set 7.002e-05 7 0.01398 17 Protein-protein-interaction for PDHX www.ncbi.nlm.ni...
Null ppi.RNF166 View Gene Set 7.516e-05 11 0.01422 19 Protein-protein-interaction for RNF166 www.ncbi.nlm.ni...
Null ppi.DTX3L View Gene Set 9.782e-05 16 0.01585 20 Protein-protein-interaction for DTX3L www.ncbi.nlm.ni...
Null ppi.DTX3 View Gene Set 0.0001015 17 0.01585 20 Protein-protein-interaction for DTX3 www.ncbi.nlm.ni...
Null ppi.UBQLN2 View Gene Set 0.000101 11 0.01585 20 Protein-protein-interaction for UBQLN2 www.ncbi.nlm.ni...
Null ppi.RNF181 View Gene Set 9.458e-05 7 0.01585 20 Protein-protein-interaction for RNF181 www.ncbi.nlm.ni...
Null ppi.G3BP1 View Gene Set 0.0001127 19 0.01621 24 Protein-protein-interaction for G3BP1 www.ncbi.nlm.ni...
Null ppi.PKD1 View Gene Set 0.0001127 13 0.01621 24 Protein-protein-interaction for PKD1 www.ncbi.nlm.ni...
Null ppi.TRIM2 View Gene Set 0.0001267 10 0.0168 26 Protein-protein-interaction for TRIM2 www.ncbi.nlm.ni...
Null ppi.PPID View Gene Set 0.0001332 10 0.0168 26 Protein-protein-interaction for PPID www.ncbi.nlm.ni...
Null ppi.LYAR View Gene Set 0.0001368 26 0.0168 26 Protein-protein-interaction for LYAR www.ncbi.nlm.ni...
Null ppi.TRIM5 View Gene Set 0.0001334 16 0.0168 26 Protein-protein-interaction for TRIM5 www.ncbi.nlm.ni...
Null ppi.CADPS2 View Gene Set 0.0001402 13 0.0168 26 Protein-protein-interaction for CADPS2 www.ncbi.nlm.ni...
Null ppi.RNF185 View Gene Set 0.0002066 13 0.02395 31 Protein-protein-interaction for RNF185 www.ncbi.nlm.ni...
Null ppi.ASCC2 View Gene Set 0.0002798 39 0.03143 32 Protein-protein-interaction for ASCC2 www.ncbi.nlm.ni...
Null ppi.PSMD14 View Gene Set 0.0003613 16 0.0371 33 Protein-protein-interaction for PSMD14 www.ncbi.nlm.ni...
Null ppi.RNF126 View Gene Set 0.0003486 8 0.0371 33 Protein-protein-interaction for RNF126 www.ncbi.nlm.ni...
Null ppi.USP14 View Gene Set 0.0003548 22 0.0371 33 Protein-protein-interaction for USP14 www.ncbi.nlm.ni...
Null ppi.TRIM43 View Gene Set 0.0003784 7 0.03778 36 Protein-protein-interaction for TRIM43 www.ncbi.nlm.ni...
Null ppi.USP49 View Gene Set 0.0004013 25 0.03898 37 Protein-protein-interaction for USP49 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 0.0004144 147 0.0392 38 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.POLR2G View Gene Set 0.0004423 9 0.03974 39 Protein-protein-interaction for POLR2G www.ncbi.nlm.ni...
Null ppi.PAAF1 View Gene Set 0.0004375 20 0.03974 39 Protein-protein-interaction for PAAF1 www.ncbi.nlm.ni...
Null ppi.SRRM2 View Gene Set 0.0004757 101 0.0409 41 Protein-protein-interaction for SRRM2 www.ncbi.nlm.ni...
Null ppi.GORASP2 View Gene Set 0.000478 19 0.0409 41 Protein-protein-interaction for GORASP2 www.ncbi.nlm.ni...
Null ppi.ANAPC4 View Gene Set 0.0005139 8 0.04295 43 Protein-protein-interaction for ANAPC4 www.ncbi.nlm.ni...
Null ppi.APC2 View Gene Set 0.0005478 8 0.04377 44 Protein-protein-interaction for APC2 www.ncbi.nlm.ni...
Null ppi.MKRN3 View Gene Set 0.000548 14 0.04377 44 Protein-protein-interaction for MKRN3 www.ncbi.nlm.ni...
Null ppi.TNKS View Gene Set 0.0005789 6 0.04523 46 Protein-protein-interaction for TNKS www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 0.0006166 43 0.04715 47 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...

Gene Set Collection: pathwayCommons.cell-map

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null AndrogenReceptor View Gene Set 7.287e-05 78 0.0007287 1 CELL_MAP - AndrogenReceptor gene set www.pathwaycomm...
Null TNF alpha/NF-kB View Gene Set 0.0003396 170 0.001698 2 CELL_MAP - TNF alpha/NF-kB gene set www.pathwaycomm...
Null EGFR1 View Gene Set 0.009516 137 0.03172 3 CELL_MAP - EGFR1 gene set www.pathwaycomm...
Null KitReceptor View Gene Set 0.01672 54 0.03364 4 CELL_MAP - KitReceptor gene set www.pathwaycomm...
Null TGFBR View Gene Set 0.01682 124 0.03364 4 CELL_MAP - TGFBR gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.nci-nature

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null LKB1 signaling events View Gene Set 2.723e-06 372 0.0005065 1 NCI_NATURE - LKB1 signaling events gene set www.pathwaycomm...
Null mTOR signaling pathway View Gene Set 2.761e-05 343 0.001712 2 NCI_NATURE - mTOR signaling pathway gene set www.pathwaycomm...
Null EGFR-dependent Endothelin signaling events View Gene Set 2.559e-05 345 0.001712 2 NCI_NATURE - EGFR-dependent Endothelin signaling events gene set www.pathwaycomm...
Null IGF1 pathway View Gene Set 0.0003004 271 0.01397 4 NCI_NATURE - IGF1 pathway gene set www.pathwaycomm...
Null Plasma membrane estrogen receptor signaling View Gene Set 0.000828 297 0.0154 5 NCI_NATURE - Plasma membrane estrogen receptor signaling gene set www.pathwaycomm...
Null Insulin Pathway View Gene Set 0.0007138 263 0.0154 5 NCI_NATURE - Insulin Pathway gene set www.pathwaycomm...
Null Arf6 signaling events View Gene Set 0.0007138 263 0.0154 5 NCI_NATURE - Arf6 signaling events gene set www.pathwaycomm...
Null ErbB2/ErbB3 signaling events View Gene Set 0.000715 38 0.0154 5 NCI_NATURE - ErbB2/ErbB3 signaling events gene set www.pathwaycomm...
Null Arf6 trafficking events View Gene Set 0.0007138 263 0.0154 5 NCI_NATURE - Arf6 trafficking events gene set www.pathwaycomm...
Null Arf1 pathway View Gene Set 0.0007608 20 0.0154 5 NCI_NATURE - Arf1 pathway gene set www.pathwaycomm...
Null Signaling events mediated by HDAC Class I View Gene Set 0.001101 114 0.01862 11 NCI_NATURE - Signaling events mediated by HDAC Class I gene set www.pathwaycomm...
Null Endothelins View Gene Set 0.001828 439 0.02834 12 NCI_NATURE - Endothelins gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.reactome

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Metabolism of proteins View Gene Set 2.267e-14 263 2.532e-11 1 REACTOME - Metabolism of proteins gene set www.pathwaycomm...
Null Gene Expression View Gene Set 1.72e-09 381 9.608e-07 2 REACTOME - Gene Expression gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of Securin View Gene Set 1.777e-08 72 5.81e-06 3 REACTOME - APC/C:Cdc20 mediated degradation of Securin gene set www.pathwaycomm...
Null Respiratory electron transport ATP synthesis by chemiosmotic coupling and heat production by uncoupling proteins. View Gene Set 2.081e-08 91 5.81e-06 3 REACTOME - Respiratory electron transport ATP synthesis by chemiosmotic coupling and heat production by uncoupling proteins. gene set www.pathwaycomm... ATP synthesis b... and heat produc...
Null tRNA Aminoacylation View Gene Set 3.932e-08 42 8.559e-06 5 REACTOME - tRNA Aminoacylation gene set www.pathwaycomm...
Null Asparagine N-linked glycosylation View Gene Set 5.364e-08 77 8.559e-06 5 REACTOME - Asparagine N-linked glycosylation gene set www.pathwaycomm...
Null APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 View Gene Set 4.958e-08 77 8.559e-06 5 REACTOME - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 gene set www.pathwaycomm...
Null Cytosolic tRNA aminoacylation View Gene Set 8.162e-08 24 1.013e-05 8 REACTOME - Cytosolic tRNA aminoacylation gene set www.pathwaycomm...
Null Autodegradation of Cdh1 by Cdh1:APC/C View Gene Set 7.714e-08 67 1.013e-05 8 REACTOME - Autodegradation of Cdh1 by Cdh1:APC/C gene set www.pathwaycomm...
Null Respiratory electron transport View Gene Set 1.148e-07 76 1.283e-05 10 REACTOME - Respiratory electron transport gene set www.pathwaycomm...
Null Regulation of ornithine decarboxylase (ODC) View Gene Set 1.732e-07 62 1.759e-05 11 REACTOME - Regulation of ornithine decarboxylase (ODC) gene set www.pathwaycomm...
Null Regulation of activated PAK-2p34 by proteasome mediated degradation View Gene Set 3.042e-07 57 2.831e-05 12 REACTOME - Regulation of activated PAK-2p34 by proteasome mediated degradation gene set www.pathwaycomm...
Null Vif-mediated degradation of APOBEC3G View Gene Set 4.574e-07 61 3.718e-05 13 REACTOME - Vif-mediated degradation of APOBEC3G gene set www.pathwaycomm...
Null Cdc20:Phospho-APC/C mediated degradation of Cyclin A View Gene Set 4.66e-07 75 3.718e-05 13 REACTOME - Cdc20:Phospho-APC/C mediated degradation of Cyclin A gene set www.pathwaycomm...
Null Post-translational protein modification View Gene Set 5.78e-07 114 4.304e-05 15 REACTOME - Post-translational protein modification gene set www.pathwaycomm...
Null Degradation of beta-catenin by the destruction complex View Gene Set 6.884e-07 56 4.523e-05 16 REACTOME - Degradation of beta-catenin by the destruction complex gene set www.pathwaycomm...
Null Signaling by Wnt View Gene Set 6.884e-07 56 4.523e-05 16 REACTOME - Signaling by Wnt gene set www.pathwaycomm...
Null HIV Infection View Gene Set 7.441e-07 194 4.561e-05 18 REACTOME - HIV Infection gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 7.758e-07 77 4.561e-05 18 REACTOME - APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null Regulation of Apoptosis View Gene Set 1.012e-06 66 5.322e-05 20 REACTOME - Regulation of Apoptosis gene set www.pathwaycomm...
Null Vpu mediated degradation of CD4 View Gene Set 1.048e-06 57 5.322e-05 20 REACTOME - Vpu mediated degradation of CD4 gene set www.pathwaycomm...
Null Translation View Gene Set 1.01e-06 120 5.322e-05 20 REACTOME - Translation gene set www.pathwaycomm...
Null SCF-beta-TrCP mediated degradation of Emi1 View Gene Set 1.261e-06 60 5.869e-05 23 REACTOME - SCF-beta-TrCP mediated degradation of Emi1 gene set www.pathwaycomm...
Null Destabilization of mRNA by AUF1 (hnRNP D0) View Gene Set 1.239e-06 63 5.869e-05 23 REACTOME - Destabilization of mRNA by AUF1 (hnRNP D0) gene set www.pathwaycomm...
Null Insulin Synthesis and Processing View Gene Set 1.353e-06 132 6.043e-05 25 REACTOME - Insulin Synthesis and Processing gene set www.pathwaycomm...
Null Regulation of mRNA Stability by Proteins that Bind AU-rich Elements View Gene Set 1.492e-06 95 6.408e-05 26 REACTOME - Regulation of mRNA Stability by Proteins that Bind AU-rich Elements gene set www.pathwaycomm...
Null Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 1.855e-06 86 7.676e-05 27 REACTOME - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null Ubiquitin-dependent degradation of Cyclin D1 View Gene Set 2.921e-06 59 0.0001125 28 REACTOME - Ubiquitin-dependent degradation of Cyclin D1 gene set www.pathwaycomm...
Null Ubiquitin-dependent degradation of Cyclin D View Gene Set 2.921e-06 59 0.0001125 28 REACTOME - Ubiquitin-dependent degradation of Cyclin D gene set www.pathwaycomm...
Null CDK-mediated phosphorylation and removal of Cdc6 View Gene Set 3.058e-06 58 0.0001139 30 REACTOME - CDK-mediated phosphorylation and removal of Cdc6 gene set www.pathwaycomm...
Null Membrane Trafficking View Gene Set 3.515e-06 84 0.0001197 31 REACTOME - Membrane Trafficking gene set www.pathwaycomm...
Null Cap-dependent Translation Initiation View Gene Set 3.536e-06 113 0.0001197 31 REACTOME - Cap-dependent Translation Initiation gene set www.pathwaycomm...
Null Eukaryotic Translation Initiation View Gene Set 3.536e-06 113 0.0001197 31 REACTOME - Eukaryotic Translation Initiation gene set www.pathwaycomm...
Null Autodegradation of the E3 ubiquitin ligase COP1 View Gene Set 4.07e-06 60 0.0001337 34 REACTOME - Autodegradation of the E3 ubiquitin ligase COP1 gene set www.pathwaycomm...
Null Ubiquitin Mediated Degradation of Phosphorylated Cdc25A View Gene Set 4.705e-06 61 0.0001476 35 REACTOME - Ubiquitin Mediated Degradation of Phosphorylated Cdc25A gene set www.pathwaycomm...
Null Regulation of APC/C activators between G1/S and early anaphase View Gene Set 4.756e-06 88 0.0001476 35 REACTOME - Regulation of APC/C activators between G1/S and early anaphase gene set www.pathwaycomm...
Null ER to Golgi Transport View Gene Set 7.183e-06 9 0.0002111 37 REACTOME - ER to Golgi Transport gene set www.pathwaycomm...
Null COPII (Coat Protein 2) Mediated Vesicle Transport View Gene Set 7.183e-06 9 0.0002111 37 REACTOME - COPII (Coat Protein 2) Mediated Vesicle Transport gene set www.pathwaycomm...
Null Ribosomal scanning and start codon recognition View Gene Set 9.901e-06 56 0.0002836 39 REACTOME - Ribosomal scanning and start codon recognition gene set www.pathwaycomm...
Null Metabolism of RNA View Gene Set 1.071e-05 174 0.0002983 40 REACTOME - Metabolism of RNA gene set www.pathwaycomm...
Null Metabolism of mRNA View Gene Set 1.095e-05 125 0.0002983 40 REACTOME - Metabolism of mRNA gene set www.pathwaycomm...
Null Stabilization of p53 View Gene Set 1.139e-05 61 0.0003029 42 REACTOME - Stabilization of p53 gene set www.pathwaycomm...
Null CDT1 association with the CDC6:ORC:origin complex View Gene Set 1.197e-05 66 0.0003111 43 REACTOME - CDT1 association with the CDC6:ORC:origin complex gene set www.pathwaycomm...
Null p53-Independent G1/S DNA damage checkpoint View Gene Set 1.471e-05 62 0.0003651 44 REACTOME - p53-Independent G1/S DNA damage checkpoint gene set www.pathwaycomm...
Null p53-Independent DNA Damage Response View Gene Set 1.471e-05 62 0.0003651 44 REACTOME - p53-Independent DNA Damage Response gene set www.pathwaycomm...
Null Formation of the ternary complex and subsequently the 43S complex View Gene Set 1.51e-05 49 0.0003668 46 REACTOME - Formation of the ternary complex and subsequently the 43S complex gene set www.pathwaycomm... and subsequentl... the 43S complex...
Null GTP hydrolysis and joining of the 60S ribosomal subunit View Gene Set 1.657e-05 106 0.0003937 47 REACTOME - GTP hydrolysis and joining of the 60S ribosomal subunit gene set www.pathwaycomm...
Null Activation of the mRNA upon binding of the cap-binding complex and eIFs and subsequent binding to 43S View Gene Set 1.724e-05 57 0.0004012 48 REACTOME - Activation of the mRNA upon binding of the cap-binding complex and eIFs and subsequent binding to 43S gene set www.pathwaycomm... and subsequent ...
Null SCF(Skp2)-mediated degradation of p27/p21 View Gene Set 2.192e-05 52 0.0004997 49 REACTOME - SCF(Skp2)-mediated degradation of p27/p21 gene set www.pathwaycomm...
Null Translation initiation complex formation View Gene Set 2.756e-05 56 0.0006157 50 REACTOME - Translation initiation complex formation gene set www.pathwaycomm...
Null Formation of HIV-1 elongation complex in the absence of HIV-1 Tat View Gene Set 2.986e-05 42 0.0006294 51 REACTOME - Formation of HIV-1 elongation complex in the absence of HIV-1 Tat gene set www.pathwaycomm...
Null Formation of RNA Pol II elongation complex View Gene Set 2.986e-05 42 0.0006294 51 REACTOME - Formation of RNA Pol II elongation complex gene set www.pathwaycomm...
Null RNA Polymerase II Transcription Elongation View Gene Set 2.986e-05 42 0.0006294 51 REACTOME - RNA Polymerase II Transcription Elongation gene set www.pathwaycomm...
Null Regulation of mitotic cell cycle View Gene Set 3.226e-05 95 0.0006551 54 REACTOME - Regulation of mitotic cell cycle gene set www.pathwaycomm...
Null APC/C-mediated degradation of cell cycle proteins View Gene Set 3.226e-05 95 0.0006551 54 REACTOME - APC/C-mediated degradation of cell cycle proteins gene set www.pathwaycomm...
Null Pyruvate metabolism and Citric Acid (TCA) cycle View Gene Set 3.729e-05 31 0.0007218 56 REACTOME - Pyruvate metabolism and Citric Acid (TCA) cycle gene set www.pathwaycomm...
Null p53-Dependent G1/S DNA damage checkpoint View Gene Set 3.748e-05 64 0.0007218 56 REACTOME - p53-Dependent G1/S DNA damage checkpoint gene set www.pathwaycomm...
Null p53-Dependent G1 DNA Damage Response View Gene Set 3.748e-05 64 0.0007218 56 REACTOME - p53-Dependent G1 DNA Damage Response gene set www.pathwaycomm...
Null RNA Polymerase II Pre-transcription Events View Gene Set 3.969e-05 58 0.0007514 59 REACTOME - RNA Polymerase II Pre-transcription Events gene set www.pathwaycomm...
Null Host Interactions of HIV factors View Gene Set 4.062e-05 132 0.0007562 60 REACTOME - Host Interactions of HIV factors gene set www.pathwaycomm...
Null Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding View Gene Set 4.18e-05 15 0.0007655 61 REACTOME - Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding gene set www.pathwaycomm...
Null Unfolded Protein Response View Gene Set 4.777e-05 63 0.000847 62 REACTOME - Unfolded Protein Response gene set www.pathwaycomm...
Null Diabetes pathways View Gene Set 4.749e-05 320 0.000847 62 REACTOME - Diabetes pathways gene set www.pathwaycomm...
Null Activation of Chaperones by IRE1alpha View Gene Set 5.026e-05 45 0.0008773 64 REACTOME - Activation of Chaperones by IRE1alpha gene set www.pathwaycomm...
Null 3' -UTR-mediated translational regulation View Gene Set 5.193e-05 105 0.0008789 65 REACTOME - 3' -UTR-mediated translational regulation gene set www.pathwaycomm...
Null L13a-mediated translational silencing of Ceruloplasmin expression View Gene Set 5.193e-05 105 0.0008789 65 REACTOME - L13a-mediated translational silencing of Ceruloplasmin expression gene set www.pathwaycomm...
Null Formation of HIV-1 elongation complex containing HIV-1 Tat View Gene Set 6.545e-05 41 0.001044 67 REACTOME - Formation of HIV-1 elongation complex containing HIV-1 Tat gene set www.pathwaycomm...
Null Tat-mediated elongation of the HIV-1 transcript View Gene Set 6.545e-05 41 0.001044 67 REACTOME - Tat-mediated elongation of the HIV-1 transcript gene set www.pathwaycomm...
Null HIV-1 Transcription Elongation View Gene Set 6.545e-05 41 0.001044 67 REACTOME - HIV-1 Transcription Elongation gene set www.pathwaycomm...
Null Apoptosis View Gene Set 6.523e-05 148 0.001044 67 REACTOME - Apoptosis gene set www.pathwaycomm...
Null Prefoldin mediated transfer of substrate to CCT/TriC View Gene Set 8.879e-05 14 0.001397 71 REACTOME - Prefoldin mediated transfer of substrate to CCT/TriC gene set www.pathwaycomm...
Null Metabolism of amino acids and derivatives View Gene Set 0.0001015 201 0.001575 72 REACTOME - Metabolism of amino acids and derivatives gene set www.pathwaycomm...
Null Influenza Viral RNA Transcription and Replication View Gene Set 0.0001064 101 0.001628 73 REACTOME - Influenza Viral RNA Transcription and Replication gene set www.pathwaycomm...
Null Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide LLO) and transfer to a nascent protein View Gene Set 0.0001201 30 0.001813 74 REACTOME - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide LLO) and transfer to a nascent protein gene set www.pathwaycomm... LLO) and transf...
Null mRNA Splicing - Minor Pathway View Gene Set 0.0001409 42 0.00203 75 REACTOME - mRNA Splicing - Minor Pathway gene set www.pathwaycomm...
Null Pausing and recovery of elongation View Gene Set 0.0001436 30 0.00203 75 REACTOME - Pausing and recovery of elongation gene set www.pathwaycomm...
Null Elongation arrest and recovery View Gene Set 0.0001436 30 0.00203 75 REACTOME - Elongation arrest and recovery gene set www.pathwaycomm...
Null HIV-1 elongation arrest and recovery View Gene Set 0.0001436 30 0.00203 75 REACTOME - HIV-1 elongation arrest and recovery gene set www.pathwaycomm...
Null Pausing and recovery of HIV-1 elongation View Gene Set 0.0001436 30 0.00203 75 REACTOME - Pausing and recovery of HIV-1 elongation gene set www.pathwaycomm...
Null Chaperonin-mediated protein folding View Gene Set 0.0002103 16 0.002937 80 REACTOME - Chaperonin-mediated protein folding gene set www.pathwaycomm...
Null G1/S DNA Damage Checkpoints View Gene Set 0.0002187 68 0.003016 81 REACTOME - G1/S DNA Damage Checkpoints gene set www.pathwaycomm...
Null Transcription View Gene Set 0.0002287 178 0.003115 82 REACTOME - Transcription gene set www.pathwaycomm...
Null Formation of a pool of free 40S subunits View Gene Set 0.0002408 95 0.003202 83 REACTOME - Formation of a pool of free 40S subunits gene set www.pathwaycomm...
Null NGF signalling via TRKA from the plasma membrane View Gene Set 0.0002386 110 0.003202 83 REACTOME - NGF signalling via TRKA from the plasma membrane gene set www.pathwaycomm...
Null Transcription of the HIV genome View Gene Set 0.0002682 60 0.003525 85 REACTOME - Transcription of the HIV genome gene set www.pathwaycomm...
Null Formation of the HIV-1 Early Elongation Complex View Gene Set 0.0002913 32 0.003677 86 REACTOME - Formation of the HIV-1 Early Elongation Complex gene set www.pathwaycomm...
Null Formation of the Early Elongation Complex View Gene Set 0.0002913 32 0.003677 86 REACTOME - Formation of the Early Elongation Complex gene set www.pathwaycomm...
Null Cyclin A:Cdk2-associated events at S phase entry View Gene Set 0.0002903 62 0.003677 86 REACTOME - Cyclin A:Cdk2-associated events at S phase entry gene set www.pathwaycomm...
Null Synthesis Secretion and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) View Gene Set 0.000293 107 0.003677 86 REACTOME - Synthesis Secretion and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) gene set www.pathwaycomm... Secretion... and Inactivatio...
Null Pausing and recovery of Tat-mediated HIV-1 elongation View Gene Set 0.0003246 29 0.003985 90 REACTOME - Pausing and recovery of Tat-mediated HIV-1 elongation gene set www.pathwaycomm...
Null Tat-mediated HIV-1 elongation arrest and recovery View Gene Set 0.0003246 29 0.003985 90 REACTOME - Tat-mediated HIV-1 elongation arrest and recovery gene set www.pathwaycomm...
Null Synthesis of GDP-mannose View Gene Set 0.0003557 5 0.004318 92 REACTOME - Synthesis of GDP-mannose gene set www.pathwaycomm...
Null Switching of origins to a post-replicative state View Gene Set 0.0003941 76 0.004683 93 REACTOME - Switching of origins to a post-replicative state gene set www.pathwaycomm...
Null Orc1 removal from chromatin View Gene Set 0.0003941 76 0.004683 93 REACTOME - Orc1 removal from chromatin gene set www.pathwaycomm...
Null Golgi to ER Retrograde Transport View Gene Set 0.0004096 10 0.004766 95 REACTOME - Golgi to ER Retrograde Transport gene set www.pathwaycomm...
Null COPI Mediated Transport View Gene Set 0.0004096 10 0.004766 95 REACTOME - COPI Mediated Transport gene set www.pathwaycomm...
Null Influenza Life Cycle View Gene Set 0.00053 138 0.006103 97 REACTOME - Influenza Life Cycle gene set www.pathwaycomm...
Null Protein folding View Gene Set 0.0005365 29 0.006115 98 REACTOME - Protein folding gene set www.pathwaycomm...
Null Folding of actin by CCT/TriC View Gene Set 0.0005678 9 0.006406 99 REACTOME - Folding of actin by CCT/TriC gene set www.pathwaycomm...
Null Synthesis of substrates in N-glycan biosythesis View Gene Set 0.0005968 16 0.006666 100 REACTOME - Synthesis of substrates in N-glycan biosythesis gene set www.pathwaycomm...
Null Abortive elongation of HIV-1 transcript in the absence of Tat View Gene Set 0.0006224 22 0.006883 101 REACTOME - Abortive elongation of HIV-1 transcript in the absence of Tat gene set www.pathwaycomm...
Null Citric acid cycle (TCA cycle) View Gene Set 0.000652 19 0.00714 102 REACTOME - Citric acid cycle (TCA cycle) gene set www.pathwaycomm...
Null Signalling by NGF View Gene Set 0.0007652 146 0.008299 103 REACTOME - Signalling by NGF gene set www.pathwaycomm...
Null HIV-1 Transcription Initiation View Gene Set 0.0009357 40 0.009035 104 REACTOME - HIV-1 Transcription Initiation gene set www.pathwaycomm...
Null RNA Polymerase II HIV-1 Promoter Escape View Gene Set 0.0009357 40 0.009035 104 REACTOME - RNA Polymerase II HIV-1 Promoter Escape gene set www.pathwaycomm...
Null RNA Polymerase III Transcription View Gene Set 0.0008586 34 0.009035 104 REACTOME - RNA Polymerase III Transcription gene set www.pathwaycomm...
Null RNA Polymerase III Abortive And Retractive Initiation View Gene Set 0.0008586 34 0.009035 104 REACTOME - RNA Polymerase III Abortive And Retractive Initiation gene set www.pathwaycomm...
Null RNA Polymerase II Promoter Escape View Gene Set 0.0009357 40 0.009035 104 REACTOME - RNA Polymerase II Promoter Escape gene set www.pathwaycomm...
Null RNA Polymerase II Transcription Initiation And Promoter Clearance View Gene Set 0.0009357 40 0.009035 104 REACTOME - RNA Polymerase II Transcription Initiation And Promoter Clearance gene set www.pathwaycomm...
Null RNA Polymerase II Transcription Initiation View Gene Set 0.0009357 40 0.009035 104 REACTOME - RNA Polymerase II Transcription Initiation gene set www.pathwaycomm...
Null RNA Polymerase II Transcription Pre-Initiation And Promoter Opening View Gene Set 0.0009357 40 0.009035 104 REACTOME - RNA Polymerase II Transcription Pre-Initiation And Promoter Opening gene set www.pathwaycomm...
Null Cholesterol biosynthesis View Gene Set 0.0009382 20 0.009035 104 REACTOME - Cholesterol biosynthesis gene set www.pathwaycomm...
Null Purine ribonucleoside monophosphate biosynthesis View Gene Set 0.0009086 7 0.009035 104 REACTOME - Purine ribonucleoside monophosphate biosynthesis gene set www.pathwaycomm...
Null Assembly of the pre-replicative complex View Gene Set 0.000881 75 0.009035 104 REACTOME - Assembly of the pre-replicative complex gene set www.pathwaycomm...
Null Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase View Gene Set 0.0009297 16 0.009035 104 REACTOME - Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase gene set www.pathwaycomm...
Null Removal of licensing factors from origins View Gene Set 0.0008421 78 0.009035 104 REACTOME - Removal of licensing factors from origins gene set www.pathwaycomm...
Null Recycling of eIF2:GDP View Gene Set 0.000951 8 0.009079 117 REACTOME - Recycling of eIF2:GDP gene set www.pathwaycomm...
Null Influenza Infection View Gene Set 0.00122 143 0.01145 118 REACTOME - Influenza Infection gene set www.pathwaycomm...
Null Viral Messenger RNA Synthesis View Gene Set 0.001219 14 0.01145 118 REACTOME - Viral Messenger RNA Synthesis gene set www.pathwaycomm...
Null Formation of tubulin folding intermediates by CCT/TriC View Gene Set 0.001243 8 0.01157 120 REACTOME - Formation of tubulin folding intermediates by CCT/TriC gene set www.pathwaycomm...
Null Regulation of DNA replication View Gene Set 0.001313 81 0.01212 121 REACTOME - Regulation of DNA replication gene set www.pathwaycomm...
Null Lysine catabolism View Gene Set 0.001467 8 0.01343 122 REACTOME - Lysine catabolism gene set www.pathwaycomm...
Null RSK activation View Gene Set 0.001694 7 0.01539 123 REACTOME - RSK activation gene set www.pathwaycomm...
Null RNA Polymerase III Transcription Initiation View Gene Set 0.001863 29 0.01665 124 REACTOME - RNA Polymerase III Transcription Initiation gene set www.pathwaycomm...
Null CREB phosphorylation View Gene Set 0.001853 7 0.01665 124 REACTOME - CREB phosphorylation gene set www.pathwaycomm...
Null Eukaryotic Translation Elongation View Gene Set 0.001985 88 0.0176 126 REACTOME - Eukaryotic Translation Elongation gene set www.pathwaycomm...
Null IRS-mediated signalling View Gene Set 0.002028 51 0.01784 127 REACTOME - IRS-mediated signalling gene set www.pathwaycomm...
Null Insulin receptor signalling cascade View Gene Set 0.002181 56 0.01896 128 REACTOME - Insulin receptor signalling cascade gene set www.pathwaycomm...
Null IRS-related events View Gene Set 0.00219 53 0.01896 128 REACTOME - IRS-related events gene set www.pathwaycomm...
Null mRNA Capping View Gene Set 0.002415 29 0.02075 130 REACTOME - mRNA Capping gene set www.pathwaycomm...
Null Transport to the Golgi and subsequent modification View Gene Set 0.002587 28 0.02206 131 REACTOME - Transport to the Golgi and subsequent modification gene set www.pathwaycomm...
Null RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription View Gene Set 0.002699 93 0.02284 132 REACTOME - RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription gene set www.pathwaycomm... RNA Polymerase ... and Mitochondri...
Null Synthesis Secretion and Deacylation of Ghrelin View Gene Set 0.002778 109 0.02333 133 REACTOME - Synthesis Secretion and Deacylation of Ghrelin gene set www.pathwaycomm... Secretion... and Deacylation...
Null Late Phase of HIV Life Cycle View Gene Set 0.002875 92 0.02396 134 REACTOME - Late Phase of HIV Life Cycle gene set www.pathwaycomm...
Null Synthesis Secretion and Inactivation of Glucagon-like Peptide-1 (GLP-1) View Gene Set 0.002951 112 0.02442 135 REACTOME - Synthesis Secretion and Inactivation of Glucagon-like Peptide-1 (GLP-1) gene set www.pathwaycomm... Secretion... and Inactivatio...
Null ChREBP activates metabolic gene expression View Gene Set 0.003339 6 0.02723 136 REACTOME - ChREBP activates metabolic gene expression gene set www.pathwaycomm...
Null Eukaryotic Translation Termination View Gene Set 0.003339 85 0.02723 136 REACTOME - Eukaryotic Translation Termination gene set www.pathwaycomm...
Null Incretin Synthesis Secretion and Inactivation View Gene Set 0.004076 115 0.03299 138 REACTOME - Incretin Synthesis Secretion and Inactivation gene set www.pathwaycomm... Secretion... and Inactivatio...
Null Nuclear Events (kinase and transcription factor activation) View Gene Set 0.004263 16 0.03426 139 REACTOME - Nuclear Events (kinase and transcription factor activation) gene set www.pathwaycomm...
Null Cyclin E associated events during G1/S transition View Gene Set 0.004298 64 0.03429 140 REACTOME - Cyclin E associated events during G1/S transition gene set www.pathwaycomm...
Null Pyruvate metabolism View Gene Set 0.004474 10 0.03545 141 REACTOME - Pyruvate metabolism gene set www.pathwaycomm...
Null Integration of energy metabolism View Gene Set 0.004691 176 0.03668 142 REACTOME - Integration of energy metabolism gene set www.pathwaycomm...
Null Peptide chain elongation View Gene Set 0.004696 85 0.03668 142 REACTOME - Peptide chain elongation gene set www.pathwaycomm...
Null Formation of transcription-coupled NER (TC-NER) repair complex View Gene Set 0.004938 29 0.03804 144 REACTOME - Formation of transcription-coupled NER (TC-NER) repair complex gene set www.pathwaycomm...
Null Dual incision reaction in TC-NER View Gene Set 0.004938 29 0.03804 144 REACTOME - Dual incision reaction in TC-NER gene set www.pathwaycomm...
Null RNA Pol II CTD phosphorylation and interaction with CE View Gene Set 0.005166 27 0.03926 146 REACTOME - RNA Pol II CTD phosphorylation and interaction with CE gene set www.pathwaycomm...
Null RNA Pol II CTD phosphorylation and interaction with CE - 11 View Gene Set 0.005166 27 0.03926 146 REACTOME - RNA Pol II CTD phosphorylation and interaction with CE - 11 gene set www.pathwaycomm...
Null Metabolism of folate and pterines View Gene Set 0.005269 8 0.03977 148 REACTOME - Metabolism of folate and pterines gene set www.pathwaycomm...
Null Viral mRNA Translation View Gene Set 0.006602 85 0.04917 149 REACTOME - Viral mRNA Translation gene set www.pathwaycomm...
Null Association of TriC/CCT with target proteins during biosynthesis View Gene Set 0.006647 9 0.04917 149 REACTOME - Association of TriC/CCT with target proteins during biosynthesis gene set www.pathwaycomm...
Null Activation of PKB View Gene Set 0.006626 4 0.04917 149 REACTOME - Activation of PKB gene set www.pathwaycomm...

Gene Set Collection: miranda.targets

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-663 View Gene Set 2.499e-06 993 0.001692 1 microRNA targets for hsa-miR-663 from miranda.targets www.mirbase.org...

Gene Set Collection: mirbase.targets

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-296-5p View Gene Set 2.37e-05 755 0.008424 1 microRNA targets for hsa-miR-296-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-484 View Gene Set 2.076e-05 733 0.008424 1 microRNA targets for hsa-miR-484 from mirbase.targets www.mirbase.org...
Null hsa-miR-612 View Gene Set 5.422e-05 685 0.009638 3 microRNA targets for hsa-miR-612 from mirbase.targets www.mirbase.org...
Null hsa-miR-940 View Gene Set 4.369e-05 660 0.009638 3 microRNA targets for hsa-miR-940 from mirbase.targets www.mirbase.org...
Null hsa-miR-661 View Gene Set 0.0001001 575 0.01423 5 microRNA targets for hsa-miR-661 from mirbase.targets www.mirbase.org...
Null hsa-miR-149 View Gene Set 0.0002696 602 0.03194 6 microRNA targets for hsa-miR-149 from mirbase.targets www.mirbase.org...
Null hsa-miR-324-3p View Gene Set 0.000333 788 0.03382 7 microRNA targets for hsa-miR-324-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-328 View Gene Set 0.0004731 685 0.03738 8 microRNA targets for hsa-miR-328 from mirbase.targets www.mirbase.org...
Null hsa-miR-615-3p View Gene Set 0.0004543 757 0.03738 8 microRNA targets for hsa-miR-615-3p from mirbase.targets www.mirbase.org...

Gene Set Collection: targetscan.targets

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-100 View Gene Set 0.000439 40 0.0357 1 microRNA targets for hsa-miR-100 from targetscan.targets www.mirbase.org...
Null hsa-miR-99a View Gene Set 0.000439 40 0.0357 1 microRNA targets for hsa-miR-99a from targetscan.targets www.mirbase.org...
Null hsa-miR-99b View Gene Set 0.000439 40 0.0357 1 microRNA targets for hsa-miR-99b from targetscan.targets www.mirbase.org...

Gene Set Collection: miRNAtargetUnion

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-296-5p View Gene Set 2.008e-05 1519 0.03132 1 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-296-5p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-663 View Gene Set 2.707e-05 1582 0.03132 1 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-663 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-615-3p View Gene Set 8.81e-05 1113 0.03593 3 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-615-3p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.targetscan.targetsUnion.hsa-miR-615-3p View Gene Set 9.318e-05 1112 0.03593 3 microRNA targets for miranda.mirbase.targetscan.targetsUnion.hsa-miR-615-3p from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-99a View Gene Set 8.159e-05 700 0.03593 3 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-99a from miRNAtargetUnion www.mirbase.org...
Null mirbase.pictar.targetscan.targetsUnion.hsa-miR-99a View Gene Set 5.31e-05 701 0.03593 3 microRNA targets for mirbase.pictar.targetscan.targetsUnion.hsa-miR-99a from miRNAtargetUnion www.mirbase.org...
Null mirbase.pictar.targetscan.targetsUnion.hsa-miR-99b View Gene Set 0.000113 744 0.03736 7 microRNA targets for mirbase.pictar.targetscan.targetsUnion.hsa-miR-99b from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-484 View Gene Set 0.0001946 1853 0.04164 8 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-484 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-572 View Gene Set 0.0001978 825 0.04164 8 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-572 from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.pictar.targetsUnion.hsa-miR-324-3p View Gene Set 0.000198 1096 0.04164 8 microRNA targets for mirbase.mirtarget2.pictar.targetsUnion.hsa-miR-324-3p from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-99b View Gene Set 0.0001486 744 0.04164 8 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-99b from miRNAtargetUnion www.mirbase.org...

Gene Set Collection: hprdBatch.UP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Androgen Receptor Signaling Pathway View Gene Set 0.0001752 437 0.003505 1 From NetPath for Androgen Receptor Signaling Pathway www.netpath.org...

Gene Set Collection: hprdBatch.DIFFERENT

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Androgen Receptor Signaling Pathway View Gene Set 0.0002622 586 0.005244 1 From NetPath for Androgen Receptor Signaling Pathway www.netpath.org...