Results

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Go to: Gene Set Collection: KEGG
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AFA results for: tSAHAda4DU

Click on the heading for any column to sort by that column.

Gene Set Collection: KEGG

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
KEGG 03040 View Gene Set 5.501e-15 128 1.177e-12 1 Spliceosome www.genome.jp/d...
KEGG 04110 View Gene Set 1.692e-07 128 1.811e-05 2 Cell cycle www.genome.jp/d...
KEGG 03050 View Gene Set 1.528e-06 48 0.000109 3 Proteasome www.genome.jp/d...
KEGG 00240 View Gene Set 4.463e-06 99 0.000191 4 Pyrimidine metabolism www.genome.jp/d...
KEGG 00970 View Gene Set 3.673e-06 41 0.000191 4 Aminoacyl-tRNA biosynthesis www.genome.jp/d...
KEGG 03018 View Gene Set 9.206e-06 59 0.0002814 6 RNA degradation www.genome.jp/d...
KEGG 03440 View Gene Set 8.323e-06 28 0.0002814 6 Homologous recombination www.genome.jp/d...
KEGG 03430 View Gene Set 4.218e-05 23 0.001128 8 Mismatch repair www.genome.jp/d...
KEGG 05016 View Gene Set 9.166e-05 184 0.00218 9 Huntington's disease www.genome.jp/d...
KEGG 03020 View Gene Set 0.0001784 29 0.003817 10 RNA polymerase www.genome.jp/d...
KEGG 03030 View Gene Set 0.0002105 36 0.004094 11 DNA replication www.genome.jp/d...
KEGG 05012 View Gene Set 0.0003035 132 0.005412 12 Parkinson's disease www.genome.jp/d...
KEGG 03420 View Gene Set 0.000344 44 0.005663 13 Nucleotide excision repair www.genome.jp/d...
KEGG 03410 View Gene Set 0.00128 34 0.01956 14 Base excision repair www.genome.jp/d...
KEGG 00310 View Gene Set 0.002566 46 0.0366 15 Lysine degradation www.genome.jp/d...
KEGG 00130 View Gene Set 0.002896 7 0.03874 16 Ubiquinone and other terpenoid-quinone biosynthesis www.genome.jp/d...
KEGG 00020 View Gene Set 0.003462 31 0.04358 17 Citrate cycle (TCA cycle) www.genome.jp/d...
KEGG 00290 View Gene Set 0.003717 11 0.04419 18 Valine leucine and isoleucine biosynthesis www.genome.jp/d...

Gene Set Collection: GO

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
GO GO:0044428 View Gene Set 2.021e-50 1938 2.7e-46 1 nuclear part amigo.geneontol...
GO GO:0005634 View Gene Set 8.022e-49 5198 5.359e-45 2 nucleus amigo.geneontol...
GO GO:0031974 View Gene Set 1.029e-47 1917 4.585e-44 3 membrane-enclosed lumen amigo.geneontol...
GO GO:0070013 View Gene Set 9.383e-46 1845 3.134e-42 4 intracellular organelle lumen amigo.geneontol...
GO GO:0043233 View Gene Set 2.419e-45 1881 6.463e-42 5 organelle lumen amigo.geneontol...
GO GO:0031981 View Gene Set 6.824e-39 1518 1.519e-35 6 nuclear lumen amigo.geneontol...
GO GO:0003676 View Gene Set 2.926e-38 2979 5.584e-35 7 nucleic acid binding amigo.geneontol...
GO GO:0006396 View Gene Set 8.991e-38 578 1.502e-34 8 RNA processing amigo.geneontol...
GO GO:0090304 View Gene Set 4.497e-35 3724 6.675e-32 9 nucleic acid metabolic process amigo.geneontol...
GO GO:0030529 View Gene Set 2.747e-32 504 3.67e-29 10 ribonucleoprotein complex amigo.geneontol...
GO GO:0034641 View Gene Set 8.866e-31 4584 1.077e-27 11 cellular nitrogen compound metabolic process amigo.geneontol...
GO GO:0006139 View Gene Set 5.736e-30 4294 6.386e-27 12 nucleobase nucleoside nucleotide and nucleic acid metabolic process amigo.geneontol...
GO GO:0044260 View Gene Set 6.821e-29 5699 7.01e-26 13 cellular macromolecule metabolic process amigo.geneontol...
GO GO:0006807 View Gene Set 4.53e-28 4698 4.323e-25 14 nitrogen compound metabolic process amigo.geneontol...
GO GO:0003723 View Gene Set 5.931e-28 732 5.283e-25 15 RNA binding amigo.geneontol...
GO GO:0000279 View Gene Set 1.488e-27 406 1.196e-24 16 M phase amigo.geneontol...
GO GO:0008380 View Gene Set 1.521e-27 300 1.196e-24 16 RNA splicing amigo.geneontol...
GO GO:0043227 View Gene Set 1.264e-26 8383 9.381e-24 18 membrane-bounded organelle amigo.geneontol...
GO GO:0043231 View Gene Set 2.868e-26 8376 2.016e-23 19 intracellular membrane-bounded organelle amigo.geneontol...
GO GO:0005654 View Gene Set 3.388e-26 939 2.263e-23 20 nucleoplasm amigo.geneontol...
GO GO:0043228 View Gene Set 4.765e-26 2690 2.894e-23 21 non-membrane-bounded organelle amigo.geneontol...
GO GO:0043232 View Gene Set 4.765e-26 2690 2.894e-23 21 intracellular non-membrane-bounded organelle amigo.geneontol...
GO GO:0005694 View Gene Set 5.88e-26 507 3.415e-23 23 chromosome amigo.geneontol...
GO GO:0043226 View Gene Set 2.099e-25 9360 1.168e-22 24 organelle amigo.geneontol...
GO GO:0043229 View Gene Set 2.585e-25 9346 1.381e-22 25 intracellular organelle amigo.geneontol...
GO GO:0022402 View Gene Set 3.429e-25 676 1.762e-22 26 cell cycle process amigo.geneontol...
GO GO:0000087 View Gene Set 8.521e-25 286 4.216e-22 27 M phase of mitotic cell cycle amigo.geneontol...
GO GO:0048285 View Gene Set 9.371e-25 286 4.471e-22 28 organelle fission amigo.geneontol...
GO GO:0000278 View Gene Set 1.689e-24 489 7.522e-22 29 mitotic cell cycle amigo.geneontol...
GO GO:0010467 View Gene Set 1.686e-24 3806 7.522e-22 29 gene expression amigo.geneontol...
GO GO:0000280 View Gene Set 2.865e-24 276 1.196e-21 31 nuclear division amigo.geneontol...
GO GO:0007067 View Gene Set 2.865e-24 276 1.196e-21 31 mitosis amigo.geneontol...
GO GO:0022403 View Gene Set 5.406e-24 522 2.189e-21 33 cell cycle phase amigo.geneontol...
GO GO:0043170 View Gene Set 1.055e-23 6274 4.145e-21 34 macromolecule metabolic process amigo.geneontol...
GO GO:0044427 View Gene Set 6.443e-23 420 2.459e-20 35 chromosomal part amigo.geneontol...
GO GO:0044237 View Gene Set 8.229e-23 7431 3.054e-20 36 cellular metabolic process amigo.geneontol...
GO GO:0000775 View Gene Set 1.924e-22 146 6.947e-20 37 chromosome centromeric region amigo.geneontol...
GO GO:0016071 View Gene Set 2.155e-22 381 7.575e-20 38 mRNA metabolic process amigo.geneontol...
GO GO:0007049 View Gene Set 1.255e-21 1006 4.299e-19 39 cell cycle amigo.geneontol...
GO GO:0005739 View Gene Set 1.74e-21 1274 5.813e-19 40 mitochondrion amigo.geneontol...
GO GO:0016070 View Gene Set 2.391e-21 2596 7.793e-19 41 RNA metabolic process amigo.geneontol...
GO GO:0044446 View Gene Set 3.013e-21 5019 9.583e-19 42 intracellular organelle part amigo.geneontol...
GO GO:0044422 View Gene Set 1.041e-20 5089 3.234e-18 43 organelle part amigo.geneontol...
GO GO:0006397 View Gene Set 1.877e-20 317 5.7e-18 44 mRNA processing amigo.geneontol...
GO GO:0032991 View Gene Set 2.492e-20 3237 7.398e-18 45 macromolecular complex amigo.geneontol...
GO GO:0000793 View Gene Set 7.69e-20 136 2.233e-17 46 condensed chromosome amigo.geneontol...
GO GO:0034660 View Gene Set 3.009e-19 236 8.554e-17 47 ncRNA metabolic process amigo.geneontol...
GO GO:0022613 View Gene Set 4.126e-19 194 1.148e-16 48 ribonucleoprotein complex biogenesis amigo.geneontol...
GO GO:0000776 View Gene Set 4.326e-19 92 1.179e-16 49 kinetochore amigo.geneontol...
GO GO:0044424 View Gene Set 1.551e-18 10976 4.144e-16 50 intracellular part amigo.geneontol...
GO GO:0005681 View Gene Set 3.477e-18 135 9.109e-16 51 spliceosomal complex amigo.geneontol...
GO GO:0005730 View Gene Set 4.065e-18 734 1.044e-15 52 nucleolus amigo.geneontol...
GO GO:0044238 View Gene Set 6.559e-18 7629 1.653e-15 53 primary metabolic process amigo.geneontol...
GO GO:0000777 View Gene Set 2.136e-17 74 5.284e-15 54 condensed chromosome kinetochore amigo.geneontol...
GO GO:0051276 View Gene Set 2.598e-17 548 6.31e-15 55 chromosome organization amigo.geneontol...
GO GO:0051301 View Gene Set 3.467e-17 358 8.271e-15 56 cell division amigo.geneontol...
GO GO:0000779 View Gene Set 4.262e-17 79 9.99e-15 57 condensed chromosome centromeric region amigo.geneontol...
GO GO:0034470 View Gene Set 5.853e-17 193 1.348e-14 58 ncRNA processing amigo.geneontol...
GO GO:0008152 View Gene Set 3.107e-16 8439 7.035e-14 59 metabolic process amigo.geneontol...
GO GO:0006996 View Gene Set 3.47e-16 1501 7.726e-14 60 organelle organization amigo.geneontol...
GO GO:0006259 View Gene Set 4.42e-16 592 9.68e-14 61 DNA metabolic process amigo.geneontol...
GO GO:0005622 View Gene Set 4.982e-16 11329 1.073e-13 62 intracellular amigo.geneontol...
GO GO:0005819 View Gene Set 2.626e-15 167 5.569e-13 63 spindle amigo.geneontol...
GO GO:0000375 View Gene Set 3.047e-15 106 6.36e-13 64 RNA splicing via transesterification reactions amigo.geneontol...
GO GO:0005759 View Gene Set 7.037e-15 223 1.424e-12 65 mitochondrial matrix amigo.geneontol...
GO GO:0031980 View Gene Set 7.037e-15 223 1.424e-12 65 mitochondrial lumen amigo.geneontol...
GO GO:0006281 View Gene Set 1.202e-14 309 2.396e-12 67 DNA repair amigo.geneontol...
GO GO:0007059 View Gene Set 3.417e-14 94 6.714e-12 68 chromosome segregation amigo.geneontol...
GO GO:0034645 View Gene Set 3.653e-14 3529 7.072e-12 69 cellular macromolecule biosynthetic process amigo.geneontol...
GO GO:0044429 View Gene Set 5.532e-14 619 1.056e-11 70 mitochondrial part amigo.geneontol...
GO GO:0044451 View Gene Set 8.793e-14 600 1.655e-11 71 nucleoplasm part amigo.geneontol...
GO GO:0009059 View Gene Set 1.189e-13 3597 2.206e-11 72 macromolecule biosynthetic process amigo.geneontol...
GO GO:0000377 View Gene Set 1.343e-13 97 2.424e-11 73 RNA splicing via transesterification reactions with bulged adenosine as nucleophile amigo.geneontol...
GO GO:0000398 View Gene Set 1.343e-13 97 2.424e-11 73 nuclear mRNA splicing via spliceosome amigo.geneontol...
GO GO:0006974 View Gene Set 1.595e-13 412 2.841e-11 75 response to DNA damage stimulus amigo.geneontol...
GO GO:0007051 View Gene Set 4.295e-13 57 7.549e-11 76 spindle organization amigo.geneontol...
GO GO:0044249 View Gene Set 6.38e-13 4326 1.107e-10 77 cellular biosynthetic process amigo.geneontol...
GO GO:0000166 View Gene Set 1.557e-12 2257 2.667e-10 78 nucleotide binding amigo.geneontol...
GO GO:0042254 View Gene Set 2.329e-12 130 3.939e-10 79 ribosome biogenesis amigo.geneontol...
GO GO:0007017 View Gene Set 2.382e-12 281 3.978e-10 80 microtubule-based process amigo.geneontol...
GO GO:0005815 View Gene Set 2.828e-12 277 4.665e-10 81 microtubule organizing center amigo.geneontol...
GO GO:0003677 View Gene Set 3.059e-12 2028 4.984e-10 82 DNA binding amigo.geneontol...
GO GO:0006399 View Gene Set 3.806e-12 118 6.127e-10 83 tRNA metabolic process amigo.geneontol...
GO GO:0006412 View Gene Set 4.132e-12 412 6.572e-10 84 translation amigo.geneontol...
GO GO:0009058 View Gene Set 8.595e-12 4436 1.351e-09 85 biosynthetic process amigo.geneontol...
GO GO:0000228 View Gene Set 9.62e-12 177 1.495e-09 86 nuclear chromosome amigo.geneontol...
GO GO:0016072 View Gene Set 1.072e-11 101 1.647e-09 87 rRNA metabolic process amigo.geneontol...
GO GO:0006364 View Gene Set 1.585e-11 97 2.406e-09 88 rRNA processing amigo.geneontol...
GO GO:0000226 View Gene Set 2.768e-11 178 4.154e-09 89 microtubule cytoskeleton organization amigo.geneontol...
GO GO:0000922 View Gene Set 3.605e-11 63 5.352e-09 90 spindle pole amigo.geneontol...
GO GO:0015630 View Gene Set 4.978e-11 587 7.308e-09 91 microtubule cytoskeleton amigo.geneontol...
GO GO:0022618 View Gene Set 6.108e-11 76 8.87e-09 92 ribonucleoprotein complex assembly amigo.geneontol...
GO GO:0005840 View Gene Set 1.091e-10 198 1.567e-08 93 ribosome amigo.geneontol...
GO GO:0005876 View Gene Set 1.979e-10 35 2.813e-08 94 spindle microtubule amigo.geneontol...
GO GO:0051028 View Gene Set 5.73e-10 90 8.058e-08 95 mRNA transport amigo.geneontol...
GO GO:0044454 View Gene Set 6.623e-10 139 9.217e-08 96 nuclear chromosome part amigo.geneontol...
GO GO:0050657 View Gene Set 8.57e-10 102 1.157e-07 97 nucleic acid transport amigo.geneontol...
GO GO:0050658 View Gene Set 8.57e-10 102 1.157e-07 97 RNA transport amigo.geneontol...
GO GO:0051236 View Gene Set 8.57e-10 102 1.157e-07 97 establishment of RNA localization amigo.geneontol...
GO GO:0008033 View Gene Set 1.296e-09 78 1.731e-07 100 tRNA processing amigo.geneontol...
GO GO:0006260 View Gene Set 1.388e-09 239 1.818e-07 101 DNA replication amigo.geneontol...
GO GO:0034621 View Gene Set 1.38e-09 458 1.818e-07 101 cellular macromolecular complex subunit organization amigo.geneontol...
GO GO:0006261 View Gene Set 1.522e-09 74 1.974e-07 103 DNA-dependent DNA replication amigo.geneontol...
GO GO:0031967 View Gene Set 1.719e-09 672 2.208e-07 104 organelle envelope amigo.geneontol...
GO GO:0031975 View Gene Set 2.312e-09 685 2.941e-07 105 envelope amigo.geneontol...
GO GO:0000070 View Gene Set 4.851e-09 37 6.058e-07 106 mitotic sister chromatid segregation amigo.geneontol...
GO GO:0006403 View Gene Set 4.831e-09 104 6.058e-07 106 RNA localization amigo.geneontol...
GO GO:0030554 View Gene Set 7.303e-09 1584 9.034e-07 108 adenyl nucleotide binding amigo.geneontol...
GO GO:0034622 View Gene Set 8.302e-09 393 1.018e-06 109 cellular macromolecular complex assembly amigo.geneontol...
GO GO:0031145 View Gene Set 9.069e-09 64 1.101e-06 110 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0051437 View Gene Set 9.445e-09 64 1.137e-06 111 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0046930 View Gene Set 1.038e-08 85 1.238e-06 112 pore complex amigo.geneontol...
GO GO:0000313 View Gene Set 1.144e-08 49 1.341e-06 113 organellar ribosome amigo.geneontol...
GO GO:0005761 View Gene Set 1.144e-08 49 1.341e-06 113 mitochondrial ribosome amigo.geneontol...
GO GO:0051439 View Gene Set 1.415e-08 68 1.633e-06 115 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0005643 View Gene Set 1.418e-08 71 1.633e-06 115 nuclear pore amigo.geneontol...
GO GO:0051351 View Gene Set 1.519e-08 74 1.734e-06 117 positive regulation of ligase activity amigo.geneontol...
GO GO:0000819 View Gene Set 1.876e-08 38 2.106e-06 118 sister chromatid segregation amigo.geneontol...
GO GO:0051443 View Gene Set 1.861e-08 71 2.106e-06 118 positive regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0032559 View Gene Set 2.279e-08 1503 2.537e-06 120 adenyl ribonucleotide binding amigo.geneontol...
GO GO:0031023 View Gene Set 2.892e-08 41 3.194e-06 121 microtubule organizing center organization amigo.geneontol...
GO GO:0016569 View Gene Set 3.411e-08 165 3.717e-06 122 covalent chromatin modification amigo.geneontol...
GO GO:0016570 View Gene Set 3.422e-08 162 3.717e-06 122 histone modification amigo.geneontol...
GO GO:0051436 View Gene Set 4.094e-08 62 4.411e-06 124 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0005524 View Gene Set 4.936e-08 1480 5.276e-06 125 ATP binding amigo.geneontol...
GO GO:0001883 View Gene Set 5.756e-08 1620 6.103e-06 126 purine nucleoside binding amigo.geneontol...
GO GO:0015931 View Gene Set 7.334e-08 118 7.691e-06 127 nucleobase nucleoside nucleotide and nucleic acid transport amigo.geneontol...
GO GO:0001882 View Gene Set 7.368e-08 1630 7.691e-06 127 nucleoside binding amigo.geneontol...
GO GO:0044455 View Gene Set 8.696e-08 133 9.006e-06 129 mitochondrial membrane part amigo.geneontol...
GO GO:0051297 View Gene Set 8.83e-08 40 9.074e-06 130 centrosome organization amigo.geneontol...
GO GO:0051340 View Gene Set 1.481e-07 85 1.511e-05 131 regulation of ligase activity amigo.geneontol...
GO GO:0005743 View Gene Set 1.612e-07 305 1.632e-05 132 mitochondrial inner membrane amigo.geneontol...
GO GO:0003735 View Gene Set 1.669e-07 158 1.677e-05 133 structural constituent of ribosome amigo.geneontol...
GO GO:0016568 View Gene Set 1.908e-07 324 1.891e-05 134 chromatin modification amigo.geneontol...
GO GO:0051438 View Gene Set 1.911e-07 82 1.891e-05 134 regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0016604 View Gene Set 1.973e-07 198 1.938e-05 136 nuclear body amigo.geneontol...
GO GO:0017076 View Gene Set 2.321e-07 1934 2.263e-05 137 purine nucleotide binding amigo.geneontol...
GO GO:0015030 View Gene Set 2.506e-07 43 2.426e-05 138 Cajal body amigo.geneontol...
GO GO:0006325 View Gene Set 2.573e-07 425 2.474e-05 139 chromatin organization amigo.geneontol...
GO GO:0033554 View Gene Set 2.676e-07 698 2.554e-05 140 cellular response to stress amigo.geneontol...
GO GO:0006310 View Gene Set 3.117e-07 130 2.951e-05 141 DNA recombination amigo.geneontol...
GO GO:0051352 View Gene Set 3.158e-07 66 2.951e-05 141 negative regulation of ligase activity amigo.geneontol...
GO GO:0051444 View Gene Set 3.158e-07 66 2.951e-05 141 negative regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0000502 View Gene Set 3.498e-07 63 3.245e-05 144 proteasome complex amigo.geneontol...
GO GO:0000075 View Gene Set 4.529e-07 109 4.173e-05 145 cell cycle checkpoint amigo.geneontol...
GO GO:0030532 View Gene Set 4.56e-07 32 4.173e-05 145 small nuclear ribonucleoprotein complex amigo.geneontol...
GO GO:0005740 View Gene Set 4.898e-07 444 4.452e-05 147 mitochondrial envelope amigo.geneontol...
GO GO:0044085 View Gene Set 5.091e-07 1167 4.595e-05 148 cellular component biogenesis amigo.geneontol...
GO GO:0030261 View Gene Set 6.127e-07 27 5.494e-05 149 chromosome condensation amigo.geneontol...
GO GO:0004386 View Gene Set 6.398e-07 144 5.698e-05 150 helicase activity amigo.geneontol...
GO GO:0007005 View Gene Set 6.906e-07 139 6.11e-05 151 mitochondrion organization amigo.geneontol...
GO GO:0031966 View Gene Set 8.969e-07 420 7.883e-05 152 mitochondrial membrane amigo.geneontol...
GO GO:0016741 View Gene Set 9.141e-07 179 7.982e-05 153 transferase activity transferring one-carbon groups amigo.geneontol...
GO GO:0032553 View Gene Set 9.268e-07 1851 7.988e-05 154 ribonucleotide binding amigo.geneontol...
GO GO:0032555 View Gene Set 9.268e-07 1851 7.988e-05 154 purine ribonucleotide binding amigo.geneontol...
GO GO:0006626 View Gene Set 9.906e-07 32 8.323e-05 156 protein targeting to mitochondrion amigo.geneontol...
GO GO:0031398 View Gene Set 9.733e-07 95 8.323e-05 156 positive regulation of protein ubiquitination amigo.geneontol...
GO GO:0070585 View Gene Set 9.906e-07 32 8.323e-05 156 protein localization in mitochondrion amigo.geneontol...
GO GO:0070925 View Gene Set 9.859e-07 57 8.323e-05 156 organelle assembly amigo.geneontol...
GO GO:0033279 View Gene Set 9.995e-07 121 8.346e-05 160 ribosomal subunit amigo.geneontol...
GO GO:0008026 View Gene Set 1.035e-06 105 8.537e-05 161 ATP-dependent helicase activity amigo.geneontol...
GO GO:0070035 View Gene Set 1.035e-06 105 8.537e-05 161 purine NTP-dependent helicase activity amigo.geneontol...
GO GO:0043234 View Gene Set 1.055e-06 2680 8.651e-05 163 protein complex amigo.geneontol...
GO GO:0006350 View Gene Set 1.171e-06 2744 9.483e-05 164 transcription amigo.geneontol...
GO GO:0003697 View Gene Set 1.167e-06 58 9.483e-05 164 single-stranded DNA binding amigo.geneontol...
GO GO:0031397 View Gene Set 1.234e-06 78 9.933e-05 166 negative regulation of protein ubiquitination amigo.geneontol...
GO GO:0000387 View Gene Set 1.35e-06 31 0.000108 167 spliceosomal snRNP assembly amigo.geneontol...
GO GO:0000792 View Gene Set 1.406e-06 52 0.0001118 168 heterochromatin amigo.geneontol...
GO GO:0043933 View Gene Set 1.443e-06 836 0.0001141 169 macromolecular complex subunit organization amigo.geneontol...
GO GO:0019866 View Gene Set 1.667e-06 334 0.000131 170 organelle inner membrane amigo.geneontol...
GO GO:0005813 View Gene Set 1.885e-06 166 0.0001472 171 centrosome amigo.geneontol...
GO GO:0006839 View Gene Set 1.938e-06 75 0.0001505 172 mitochondrial transport amigo.geneontol...
GO GO:0008168 View Gene Set 1.963e-06 176 0.0001516 173 methyltransferase activity amigo.geneontol...
GO GO:0045333 View Gene Set 2.101e-06 100 0.0001613 174 cellular respiration amigo.geneontol...
GO GO:0065003 View Gene Set 2.604e-06 763 0.0001988 175 macromolecular complex assembly amigo.geneontol...
GO GO:0006473 View Gene Set 2.897e-06 61 0.0002199 176 protein amino acid acetylation amigo.geneontol...
GO GO:0051225 View Gene Set 3.215e-06 22 0.0002427 177 spindle assembly amigo.geneontol...
GO GO:0044265 View Gene Set 3.287e-06 479 0.0002467 178 cellular macromolecule catabolic process amigo.geneontol...
GO GO:0010498 View Gene Set 3.415e-06 166 0.0002535 179 proteasomal protein catabolic process amigo.geneontol...
GO GO:0000940 View Gene Set 3.402e-06 12 0.0002535 179 outer kinetochore of condensed chromosome amigo.geneontol...
GO GO:0007006 View Gene Set 3.993e-06 29 0.0002948 181 mitochondrial membrane organization amigo.geneontol...
GO GO:0071103 View Gene Set 4.036e-06 140 0.0002963 182 DNA conformation change amigo.geneontol...
GO GO:0004812 View Gene Set 4.555e-06 46 0.0003289 183 aminoacyl-tRNA ligase activity amigo.geneontol...
GO GO:0016875 View Gene Set 4.555e-06 46 0.0003289 183 ligase activity forming carbon-oxygen bonds amigo.geneontol...
GO GO:0016876 View Gene Set 4.555e-06 46 0.0003289 183 ligase activity forming aminoacyl-tRNA and related compounds amigo.geneontol...
GO GO:0043967 View Gene Set 4.628e-06 25 0.0003324 186 histone H4 acetylation amigo.geneontol...
GO GO:0044452 View Gene Set 5.131e-06 28 0.0003665 187 nucleolar part amigo.geneontol...
GO GO:0008094 View Gene Set 5.243e-06 61 0.0003726 188 DNA-dependent ATPase activity amigo.geneontol...
GO GO:0006511 View Gene Set 5.274e-06 296 0.0003728 189 ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0009451 View Gene Set 5.488e-06 51 0.0003859 190 RNA modification amigo.geneontol...
GO GO:0019941 View Gene Set 5.634e-06 302 0.00039 191 modification-dependent protein catabolic process amigo.geneontol...
GO GO:0043632 View Gene Set 5.634e-06 302 0.00039 191 modification-dependent macromolecule catabolic process amigo.geneontol...
GO GO:0035267 View Gene Set 5.611e-06 14 0.00039 191 NuA4 histone acetyltransferase complex amigo.geneontol...
GO GO:0004527 View Gene Set 5.671e-06 57 0.0003905 194 exonuclease activity amigo.geneontol...
GO GO:0010556 View Gene Set 5.843e-06 2901 0.0004003 195 regulation of macromolecule biosynthetic process amigo.geneontol...
GO GO:0060255 View Gene Set 6.107e-06 3411 0.0004163 196 regulation of macromolecule metabolic process amigo.geneontol...
GO GO:0043161 View Gene Set 6.461e-06 162 0.0004382 197 proteasomal ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0043189 View Gene Set 6.585e-06 15 0.0004443 198 H4/H2A histone acetyltransferase complex amigo.geneontol...
GO GO:0005874 View Gene Set 6.798e-06 284 0.0004564 199 microtubule amigo.geneontol...
GO GO:0031396 View Gene Set 7.682e-06 121 0.0005132 200 regulation of protein ubiquitination amigo.geneontol...

Gene Set Collection: Broad.c1.CYTOBAND

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad chr22q13 View Gene Set 6.668e-06 179 0.002174 1 Genes in cytogenetic band chr22q13 www.broad.mit.e...
Broad chr4p16 View Gene Set 2.55e-05 126 0.004156 2 Genes in cytogenetic band chr4p16 www.broad.mit.e...
Broad chr19p13 View Gene Set 0.0001317 514 0.01006 3 Genes in cytogenetic band chr19p13 www.broad.mit.e...
Broad chr10q26 View Gene Set 0.0001433 102 0.01006 3 Genes in cytogenetic band chr10q26 www.broad.mit.e...
Broad chr9q34 View Gene Set 0.0001652 204 0.01006 3 Genes in cytogenetic band chr9q34 www.broad.mit.e...
Broad chr16p13 View Gene Set 0.0001852 254 0.01006 3 Genes in cytogenetic band chr16p13 www.broad.mit.e...
Broad chr17q25 View Gene Set 0.0004468 172 0.02081 7 Genes in cytogenetic band chr17q25 www.broad.mit.e...

Gene Set Collection: Broad.c2.CGP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad PUJANA_BRCA1_PCC_NETWORK View Gene Set 8.942e-59 1582 2.139e-55 1 Genes constituting the BRCA1-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA1 [Gene ID=672] across a compendium of normal tissues. www.broad.mit.e...
Broad PUJANA_CHEK2_PCC_NETWORK View Gene Set 5.568e-58 744 6.659e-55 2 Genes constituting the CHEK2-PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient PCC >= 0.4) with that of CHEK2 [Gene ID=11200]. www.broad.mit.e...
Broad KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP View Gene Set 1.051e-56 1180 6.287e-54 3 Genes up-regulated in TC71 and EWS502 cells (Ewing's sarcoma) upon knockdown of the EWSR1-FLII fusion [Gene ID=2130 2314]. www.broad.mit.e...
Broad CAIRO_HEPATOBLASTOMA_CLASSES_UP View Gene Set 9.381e-57 577 6.287e-54 3 Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). www.broad.mit.e...
Broad MANALO_HYPOXIA_DN View Gene Set 1.011e-53 276 4.838e-51 5 Genes down-regulated in response to both hypoxia and overexpression of an active form of HIF1A [Gene ID=3091]. www.broad.mit.e...
Broad DODD_NASOPHARYNGEAL_CARCINOMA_DN View Gene Set 1.673e-46 1253 6.671e-44 6 Genes down-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN View Gene Set 2.33e-40 920 7.961e-38 7 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h. www.broad.mit.e...
Broad WONG_EMBRYONIC_STEM_CELL_CORE View Gene Set 7.053e-38 331 2.109e-35 8 The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module. www.broad.mit.e...
Broad PUJANA_BRCA2_PCC_NETWORK View Gene Set 1.782e-34 410 4.737e-32 9 Genes constituting the BRCA2-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA2 [Gene ID=675] across a compendium of normal tissues. www.broad.mit.e...
Broad SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP View Gene Set 5.826e-34 143 1.394e-31 10 Up-regulated genes whose expression correlated with histologic grade of invasive breast cancer tumors: comparison of grade 1 vs grade 3. www.broad.mit.e...
Broad WEI_MYCN_TARGETS_WITH_E_BOX View Gene Set 1.76e-32 757 3.827e-30 11 Genes whose promoters contain E-box motifs and whose expression changed in MYCN-3 cells (neuroblastoma) upon induction of MYCN [Gene ID=4613]. www.broad.mit.e...
Broad ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER View Gene Set 4.501e-32 138 8.971e-30 12 The 'Cervical Cancer Proliferation Cluster' (CCPC): genes whose expression in cervical carcinoma positively correlates with that of the HPV E6 and E7 oncogenes; they are also differentially expressed according to disease outcome. www.broad.mit.e...
Broad MUELLER_PLURINET View Gene Set 9.636e-31 294 1.773e-28 13 Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells embryonical carcinomas and induced pluripotent cells). www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN View Gene Set 9.28e-29 832 1.585e-26 14 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. www.broad.mit.e...
Broad SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 View Gene Set 4.631e-28 435 7.385e-26 15 Cluster 6 of method A: up-regulation of these genes in patients with non???small cell lung cancer (NSCLC) predicts poor survival outcome. www.broad.mit.e...
Broad BENPORATH_PROLIFERATION View Gene Set 3.979e-27 140 5.949e-25 16 Set 'Proliferation Cluster': genes defined in human breast tumor expression data. www.broad.mit.e...
Broad KOBAYASHI_EGFR_SIGNALING_24HR_DN View Gene Set 9.274e-27 243 1.305e-24 17 Genes down-regulated in H1975 cells (non-small cell lung cancer NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 24h. www.broad.mit.e...
Broad BERENJENO_TRANSFORMED_BY_RHOA_UP View Gene Set 6.073e-26 485 8.07e-24 18 Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [Gene ID=387] off plasmid vector. www.broad.mit.e...
Broad TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C View Gene Set 7.151e-26 436 9.003e-24 19 Genes down-regulated in HCT116 cells (colon cancer) upon expression of MIR34B or MIR34C [Gene ID=407041 407042] microRNAs. www.broad.mit.e...
Broad BENPORATH_CYCLING_GENES View Gene Set 5.653e-25 630 6.761e-23 20 Genes showing cell-cycle stage-specific expression [PMID=12058064]. www.broad.mit.e...
Broad PUJANA_XPRSS_INT_NETWORK View Gene Set 5.513e-24 164 6.279e-22 21 Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200] in a compendium of normal tissues. www.broad.mit.e...
Broad MISSIAGLIA_REGULATED_BY_METHYLATION_DN View Gene Set 7.231e-24 96 7.862e-22 22 Genes down-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668] a DNA hypomethylating agent similar to azacitidine [PubChem=9444]. www.broad.mit.e...
Broad CROONQUIST_IL6_DEPRIVATION_DN View Gene Set 2.222e-23 80 2.311e-21 23 Genes down-regulated in the ANBL-6 cell line (multiple myeloma MM) after withdrawal of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad WINNEPENNINCKX_MELANOMA_METASTASIS_UP View Gene Set 1.934e-22 152 1.928e-20 24 Genes from the 254-gene classifier which were up-regulated in melanoma patients with a reported distant metastasis within 4 years. www.broad.mit.e...
Broad WHITEFORD_PEDIATRIC_CANCER_MARKERS View Gene Set 7.009e-22 92 6.706e-20 25 Differentially expressed genes in a panel of xenografts representing 8 common pediatric tumors compared to the normal tissues. www.broad.mit.e...
Broad NUYTTEN_EZH2_TARGETS_DN View Gene Set 1.246e-21 859 1.147e-19 26 Genes down-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [Gene ID=2146] by RNAi. www.broad.mit.e...
Broad BLUM_RESPONSE_TO_SALIRASIB_DN View Gene Set 2.034e-21 332 1.802e-19 27 Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [Gene ID=3265]. www.broad.mit.e...
Broad CROONQUIST_NRAS_SIGNALING_DN View Gene Set 5.317e-20 62 4.542e-18 28 Genes down-regulated in ANBL-6 cell line (multiple myeloma MM) expressing a constantly active form of NRAS [Gene ID=4893] off a plasmid vector compared to those grown in the presence of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP View Gene Set 1.243e-19 180 1.025e-17 29 Genes up-regulated in quiescent CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors compared to the dividing cells from CML (chronic myeloid leukemia) patients. www.broad.mit.e...
Broad KANG_DOXORUBICIN_RESISTANCE_UP View Gene Set 4.723e-19 53 3.766e-17 30 Genes differentialy expressed in gastric cancer cell lines: doxorubicin [PubChem=31703] resistant vs sensitive. www.broad.mit.e...
Broad FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP View Gene Set 6.452e-19 144 4.979e-17 31 Genes up-regulated in genomically unstable Ewing's sarcoma tumors compared to the stable ones. www.broad.mit.e...
Broad VECCHI_GASTRIC_CANCER_EARLY_UP View Gene Set 7.601e-19 408 5.682e-17 32 Up-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. www.broad.mit.e...
Broad MOOTHA_MITOCHONDRIA View Gene Set 1.534e-18 433 1.112e-16 33 Mitochondrial genes www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_24HR_UP View Gene Set 1.606e-18 537 1.13e-16 34 Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h. www.broad.mit.e...
Broad HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP View Gene Set 5.007e-18 93 3.422e-16 35 Genes up-regulated during differentiation from large pre-BII to small pre-BII lymphocyte. www.broad.mit.e...
Broad KAUFFMANN_MELANOMA_RELAPSE_UP View Gene Set 7.406e-17 57 4.921e-15 36 DNA repair and replication genes up-regulated in melanoma patients who will relapse vs patients who will not. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP View Gene Set 1.589e-16 589 1.027e-14 37 Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. www.broad.mit.e...
Broad CHANG_CYCLING_GENES View Gene Set 1.925e-16 49 1.212e-14 38 Fibroblast serum response genes showing periodic expression during the cell cycle; excluded from the core serum response signature. www.broad.mit.e...
Broad MOOTHA_HUMAN_MITODB_6_2002 View Gene Set 3.588e-16 420 2.201e-14 39 Mitochondrial genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. www.broad.mit.e...
Broad PUJANA_BRCA_CENTERED_NETWORK View Gene Set 9.72e-16 92 5.812e-14 40 Genes constituting the BRCA-centered network (BCN). www.broad.mit.e...
Broad GRADE_COLON_CANCER_UP View Gene Set 1.192e-15 711 6.954e-14 41 Up-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples. www.broad.mit.e...
Broad TARTE_PLASMA_CELL_VS_PLASMABLAST_DN View Gene Set 2.177e-15 303 1.24e-13 42 Genes down-regulated in mature plasma cells compared with plasmablastic B lymphocytes. www.broad.mit.e...
Broad KAUFFMANN_DNA_REPAIR_GENES View Gene Set 3.28e-15 205 1.824e-13 43 Genes involved in DNA repair compiled manually by the authors. www.broad.mit.e...
Broad HORIUCHI_WTAP_TARGETS_DN View Gene Set 1.399e-14 289 7.606e-13 44 Genes down-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [Gene ID=9589] by RNAi. www.broad.mit.e...
Broad GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN View Gene Set 1.473e-14 86 7.828e-13 45 Genes down-regulated in quiescent vs dividing CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors. www.broad.mit.e...
Broad ZHAN_MULTIPLE_MYELOMA_PR_UP View Gene Set 1.547e-14 43 8.042e-13 46 Top 50 up-regulated genes in cluster PR of multiple myeloma samples characterized by increased expression of proliferation and cell cycle genes. www.broad.mit.e...
Broad CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN View Gene Set 1.82e-14 639 9.265e-13 47 Genes down-regulated in APL (acute promyeolocytic leukemia) blasts expressing PML-RARA fusion [Gene ID=5371 5914] compared to normal promyeloblasts. www.broad.mit.e...
Broad FARMER_BREAST_CANCER_CLUSTER_2 View Gene Set 2.105e-14 33 1.028e-12 48 Cluster 2: selected proliferation and 8q amplicon genes clustered together across breast cancer samples. www.broad.mit.e...
Broad AMUNDSON_GAMMA_RADIATION_RESPONSE View Gene Set 2.068e-14 36 1.028e-12 48 Genes down-regulated across the entire panel of NCI-60 cell lines in response to gamma radiation. www.broad.mit.e...
Broad MARKEY_RB1_ACUTE_LOF_DN View Gene Set 2.402e-14 201 1.149e-12 50 Genes down-regulated in adult fibroblasts with inactivated RB1 [Gene ID=5925] by Cre-lox: acute loss of function (LOF) of RB1. www.broad.mit.e...
Broad GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN View Gene Set 3.185e-14 148 1.494e-12 51 Genes down-regulated in the A673 cells (Ewing sarcoma) after double knockdown of both FLI1 and DAX1 [Gene ID=2313 190] by RNAi. www.broad.mit.e...
Broad ODONNELL_TFRC_TARGETS_DN View Gene Set 4.889e-14 131 2.249e-12 52 Genes dpwn-regulated in P493-6 cells (B lymphocyte) upon knockdown of TFRC [Gene ID=7037] by RNAi. www.broad.mit.e...
Broad PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP View Gene Set 5.754e-14 53 2.597e-12 53 The XPRSS-Int network genes up-regulated in breast tumors from patients with germline mutations in BRCA1 [Gene ID=672] compared to those with the wild type allele. www.broad.mit.e...
Broad GARY_CD5_TARGETS_DN View Gene Set 1.447e-13 415 6.408e-12 54 Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. www.broad.mit.e...
Broad PUJANA_ATM_PCC_NETWORK View Gene Set 3.672e-13 1375 1.597e-11 55 Genes constituting the ATM-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of ATM [Gene ID=472] across a compendium of normal tissues. www.broad.mit.e...
Broad BASAKI_YBX1_TARGETS_UP View Gene Set 6.191e-13 279 2.645e-11 56 Genes up-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [Gene ID=4904] knockdown by RNAi. www.broad.mit.e...
Broad LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN View Gene Set 1.617e-12 158 6.786e-11 57 Genes down-regulated in Wilm's tumor samples compared to fetal kidney. www.broad.mit.e...
Broad RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN View Gene Set 3.132e-12 351 1.281e-10 58 Genes down-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids. www.broad.mit.e...
Broad FUJII_YBX1_TARGETS_DN View Gene Set 3.159e-12 139 1.281e-10 58 Genes down-regulated in MCF-7 cells (breast cancer) after knockdown of YBX1 [Gene ID=4904] by RNAi. www.broad.mit.e...
Broad MORI_LARGE_PRE_BII_LYMPHOCYTE_UP View Gene Set 4.85e-12 52 1.934e-10 60 Up-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Large Pre-BII stage. www.broad.mit.e...
Broad LINDGREN_BLADDER_CANCER_CLUSTER_3_UP View Gene Set 5.301e-12 314 2.079e-10 61 Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM View Gene Set 5.444e-12 154 2.1e-10 62 Cluster 7: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] and down-regulated by the combination of MYC and serum. www.broad.mit.e...
Broad FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN View Gene Set 7.421e-12 43 2.818e-10 63 Genes down-regulated in MCF-7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4-hydroxytamoxifen raloxifene or ICI 182780 but not by estradiol [PubChem=44959 5035 3478439 5757]. www.broad.mit.e...
Broad YU_MYC_TARGETS_UP View Gene Set 9.776e-12 37 3.654e-10 64 Genes up-regulated in B cell lymphoma tumors expressing an activated form of MYC [Gene ID=4609]. www.broad.mit.e...
Broad PAL_PRMT5_TARGETS_UP View Gene Set 1.339e-11 178 4.926e-10 65 Genes up-regulated in NIH-3T3 cells (fibroblast) after knockdown of PRMT5 [Gene ID=10419] by RNAi. www.broad.mit.e...
Broad FOURNIER_ACINAR_DEVELOPMENT_LATE_2 View Gene Set 1.58e-11 265 5.726e-10 66 Genes identified by method 2 as coordinately down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro. www.broad.mit.e...
Broad MITSIADES_RESPONSE_TO_APLIDIN_DN View Gene Set 1.957e-11 241 6.988e-10 67 Genes down-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164] a marine-derived compound with potential anti-cancer properties. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP View Gene Set 3.2e-11 184 1.126e-09 68 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G3 defined by unsupervised clustering. www.broad.mit.e...
Broad KAUFFMANN_DNA_REPLICATION_GENES View Gene Set 5.539e-11 128 1.92e-09 69 Genes involved in DNA replication compiled manually by the authors. www.broad.mit.e...
Broad DANG_BOUND_BY_MYC View Gene Set 7.667e-11 1045 2.62e-09 70 Genes whose promoters are bound by MYC [Gene ID=4609] according to MYC Target Gene Database. www.broad.mit.e...
Broad WONG_MITOCHONDRIA_GENE_MODULE View Gene Set 8.98e-11 208 3.025e-09 71 Genes that comprise the mitochondria gene module www.broad.mit.e...
Broad WELCSH_BRCA1_TARGETS_1_DN View Gene Set 1.194e-10 124 3.912e-09 72 Upregulated by induction of exogenous BRCA1 in EcR-293 cells www.broad.mit.e...
Broad LEE_EARLY_T_LYMPHOCYTE_UP View Gene Set 1.179e-10 80 3.912e-09 72 Genes up-regulated at early stages of progenitor T lymphocyte maturation compared to the late stages. www.broad.mit.e...
Broad MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN View Gene Set 4.424e-10 53 1.43e-08 74 Genes commonly down-regulated in SK-N-BE cells (neuroblastoma) after RNAi knockdown of CCND1 and CDK4 [Gene ID=595 1019]. www.broad.mit.e...
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP View Gene Set 5.23e-10 469 1.668e-08 75 Genes up-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. www.broad.mit.e...
Broad CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP View Gene Set 5.504e-10 135 1.732e-08 76 Top 200 marker genes up-regulated in the 'proliferation' subclass of hepatocellular carcinoma (HCC); characterized by increased proliferation high levels of serum AFP [Gene ID=174] and chromosomal instability. www.broad.mit.e...
Broad LE_EGR2_TARGETS_UP View Gene Set 5.712e-10 100 1.774e-08 77 Genes up-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [Gene ID=1959]. www.broad.mit.e...
Broad RHODES_UNDIFFERENTIATED_CANCER View Gene Set 6.756e-10 60 2.072e-08 78 Genes commonly up-regulated in undifferentiated cancer relative to well-differentiated cancer based on the meta-analysis of the OncoMine gene expression database. www.broad.mit.e...
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN View Gene Set 9.032e-10 51 2.735e-08 79 Genes from the turquoise module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphocholine (oxPAPC). www.broad.mit.e...
Broad REN_BOUND_BY_E2F View Gene Set 1.353e-09 47 4.045e-08 80 Genes whose promoters were bound by E2F1 [Gene ID=1869] and E2F4 [Gene ID=1874] in the primary fibroblasts WI-38 by ChIP on chip assay. www.broad.mit.e...
Broad CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP View Gene Set 1.685e-09 135 4.976e-08 81 Genes up-regulated in CD4+ [Gene ID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]. www.broad.mit.e...
Broad ZHANG_BREAST_CANCER_PROGENITORS_UP View Gene Set 2.066e-09 370 6.026e-08 82 Genes changed in cancer stem cells isolated from mammary tumors compared to the non-tumorigenic cells. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN View Gene Set 2.569e-09 308 7.404e-08 83 Genes down-regulated in non-metastatic breast cancer tumors having type 1 amplification in the 20q13 region; involves ZNF217 [Gene ID=7764] locus only. www.broad.mit.e...
Broad SCHUHMACHER_MYC_TARGETS_UP View Gene Set 4.372e-09 68 1.245e-07 84 Genes up-regulated in P493-6 cells (Burkitt's lymphoma) induced to express MYC [Gene ID=4609]. www.broad.mit.e...
Broad LY_AGING_MIDDLE_DN View Gene Set 4.91e-09 15 1.382e-07 85 Genes down-regulated in fibroblasts from middle-age individuals compared to those from the young donors. www.broad.mit.e...
Broad WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 View Gene Set 6.369e-09 36 1.771e-07 86 Genes downstream of both CDKN1A and TP53 [Gene ID=1026 7157] in 2774qw1 cells (ovarian cancer). www.broad.mit.e...
Broad BIDUS_METASTASIS_UP View Gene Set 1.193e-08 203 3.279e-07 87 Genes up-regulated in endometroid endometrial tumors from patients with lymph node metastases compared to those without the metastases. www.broad.mit.e...
Broad DANG_MYC_TARGETS_UP View Gene Set 1.496e-08 127 4.067e-07 88 Genes up-regulated by MYC [Gene ID=4609] and whose promoters are bound by MYC according to MYC Target Gene Database. www.broad.mit.e...
Broad ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN View Gene Set 2.456e-08 42 6.602e-07 89 Genes down-regulated in P493-6 cells (B lymphocyte) by MYC [Gene ID=4609] and up-regulated by RNAi knockdown of TFRC [Gene ID=7037]. www.broad.mit.e...
Broad SONG_TARGETS_OF_IE86_CMV_PROTEIN View Gene Set 2.967e-08 49 7.885e-07 90 Cellular genes up-regulated in forskin fibroblasts by expression of CMV EI86 protein off an adenovirus vector. www.broad.mit.e...
Broad LY_AGING_OLD_DN View Gene Set 7.734e-08 47 2.033e-06 91 Genes up-regulated in fibroblasts from old individuals compared to those from young donors. www.broad.mit.e...
Broad EGUCHI_CELL_CYCLE_RB1_TARGETS View Gene Set 8.064e-08 19 2.097e-06 92 RB1 [Gene ID=5925] target genes involved in cell cycle regulation: genes down-regulated by doxorubicin [PubChem=31703] only in cells expressing RB1. www.broad.mit.e...
Broad MORI_IMMATURE_B_LYMPHOCYTE_DN View Gene Set 9.43e-08 52 2.426e-06 93 Down-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the immature B stage. www.broad.mit.e...
Broad FURUKAWA_DUSP6_TARGETS_PCI35_DN View Gene Set 1.068e-07 66 2.719e-06 94 Genes down-regulated in PCI-35 cells (pancreatic cancer lack endogenous DUSP6 [Gene ID=1848]) upon expression of DUSP6 off an adenoviral vector. www.broad.mit.e...
Broad BENPORATH_MYC_MAX_TARGETS View Gene Set 1.812e-07 768 4.561e-06 95 Set 'Myc targets2': targets of c-Myc [Gene ID=4609] and Max [Gene ID=4149] identified by ChIP on chip in a Burkitt???s lymphoma cell line; overlap set. www.broad.mit.e...
Broad GRADE_COLON_AND_RECTAL_CANCER_UP View Gene Set 2.259e-07 213 5.628e-06 96 Up-regulated genes in both rectal and colon carcinoma compared to normal mucosa samples. www.broad.mit.e...
Broad KUMAMOTO_RESPONSE_TO_NUTLIN_3A_DN View Gene Set 2.296e-07 10 5.663e-06 97 Genes down-regulated in response to nutlin-3a [PubChem=216345] an inhibitor of MDM2 [Gene ID=4193] in skin fibroblast cultures after knockdown of TP53 [Gene ID=7157] by RNAi. www.broad.mit.e...
Broad WEST_ADRENOCORTICAL_TUMOR_UP View Gene Set 2.592e-07 283 6.328e-06 98 Up-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue. www.broad.mit.e...
Broad FINETTI_BREAST_CANCER_KINOME_RED View Gene Set 3.135e-07 15 7.498e-06 99 Genes in the red cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. www.broad.mit.e...
Broad FINETTI_BREAST_CANCER_BASAL_VS_LUMINAL View Gene Set 3.135e-07 15 7.498e-06 99 Protein kinases distinguishing between basal and luminal A subtypes of breast cancer. www.broad.mit.e...
Broad ELVIDGE_HYPOXIA_DN View Gene Set 3.595e-07 136 8.515e-06 101 Genes down-regulated in MCF7 cells (breast cancer) under hypoxia conditions. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 View Gene Set 4.063e-07 131 9.528e-06 102 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 14. www.broad.mit.e...
Broad SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY View Gene Set 7.581e-07 31 1.761e-05 103 Cluster 3: genes strongly up-regulated in B493-6 cells (B lymphocytes) by a combination of MYC [Gene ID=4609] and serum but not by each of them alone. www.broad.mit.e...
Broad DAIRKEE_TERT_TARGETS_UP View Gene Set 8.571e-07 317 1.971e-05 104 Genes up-regulated in non-spontaneously immortalizing (NSI) primary breast cancer tumor cultures upon expression of TERT [Gene ID=7015] off a retroviral vector. www.broad.mit.e...
Broad BENPORATH_ES_1 View Gene Set 1.04e-06 367 2.369e-05 105 Set 'ES exp1': genes overexpressed in human embryonic stem cells according to 5 or more out of 20 profiling studies. www.broad.mit.e...
Broad RUIZ_TNC_TARGETS_DN View Gene Set 1.119e-06 138 2.524e-05 106 Genes down-regulated in T98G cells (glioblastoma) by TNC [Gene ID=3371]. www.broad.mit.e...
Broad NADERI_BREAST_CANCER_PROGNOSIS_UP View Gene Set 1.347e-06 37 3.012e-05 107 Up-regulated genes in the breast cancer prognostic signature of 70 genes that significantly correlated with survival. www.broad.mit.e...
Broad RHODES_CANCER_META_SIGNATURE View Gene Set 1.567e-06 54 3.439e-05 108 Genes commonly up-regulated in cancer relative to normal tissue according to the meta-analysis of the OncoMine gene expression database. www.broad.mit.e...
Broad ZHANG_RESPONSE_TO_CANTHARIDIN_DN View Gene Set 1.558e-06 60 3.439e-05 108 Genes down-regulated in HL-60 cells (promyeloid leukemia) by cantharidin [PubChem=6708701]. www.broad.mit.e...
Broad PUJANA_BREAST_CANCER_LIT_INT_NETWORK View Gene Set 1.627e-06 100 3.538e-05 110 Genes constituting the LIT-Int network of proteins interacting with breast cancer reference proteins BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200]; the interactions were manually curated from the literature. www.broad.mit.e...
Broad SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN View Gene Set 1.735e-06 22 3.74e-05 111 Cell cycle genes changed in H1299 cells (lung cancer) after overexpression of either P53 [Gene ID=7157] or P73 [Gene ID=7161]. www.broad.mit.e...
Broad WAKASUGI_HAVE_ZNF143_BINDING_SITES View Gene Set 1.857e-06 55 3.966e-05 112 DNA repair genes whose promoters contain putative ZNF143 [Gene ID=7702] binding sites. www.broad.mit.e...
Broad DANG_REGULATED_BY_MYC_UP View Gene Set 1.899e-06 65 4.02e-05 113 Genes up-regulated by MYC [Gene ID=4609] according to the MYC Target Gene Database. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP View Gene Set 2.01e-06 45 4.217e-05 114 Cluster 5: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] alone or in combination with serum but not by serum alone. www.broad.mit.e...
Broad MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP View Gene Set 2.22e-06 10 4.618e-05 115 Up-regulated genes predicting poor survival of patients with thyroid carcinoma. www.broad.mit.e...
Broad WONG_PROTEASOME_GENE_MODULE View Gene Set 2.376e-06 46 4.9e-05 116 Genes that comprise the proteasome gene module www.broad.mit.e...
Broad RIZ_ERYTHROID_DIFFERENTIATION View Gene Set 2.42e-06 71 4.947e-05 117 Selected gradually up-regulated genes in the TLX1 [Gene ID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). www.broad.mit.e...
Broad RAMALHO_STEMNESS_UP View Gene Set 3.02e-06 192 6.122e-05 118 Genes enriched in embryonic neural and hematopoietic stem cells. www.broad.mit.e...
Broad NAKAMURA_CANCER_MICROENVIRONMENT_DN View Gene Set 3.69e-06 45 7.418e-05 119 Genes down-regulated in pancreatic cancer cells grown in orthotopic xenograft tumors compared to those grown in vitro. www.broad.mit.e...
Broad IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR View Gene Set 3.872e-06 100 7.718e-05 120 Genes in the expression cluster 'Early Progenitors Shared': up-regulated in hematopoietic progenitors from adult bone marrow and from fetal liver. www.broad.mit.e...
Broad ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN View Gene Set 4.135e-06 61 8.175e-05 121 Genes down-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]. www.broad.mit.e...
Broad TANG_SENESCENCE_TP53_TARGETS_DN View Gene Set 5.198e-06 40 0.0001019 122 Genes down-regulated in WI-38 cells (senescent primary fibroblasts) after inactivation of TP53 [Gene ID=7157] by GSE56 polypeptide. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 View Gene Set 5.402e-06 165 0.0001051 123 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 17. www.broad.mit.e...
Broad MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN View Gene Set 5.561e-06 121 0.0001073 124 Genes distinguishing in multiple myeloma (MM) samples with lower expression of TACI [Gene ID=23495]. www.broad.mit.e...
Broad DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP View Gene Set 6.41e-06 1353 0.0001227 125 Genes up-regulated in CD34+ [Gene ID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients compared to those from normal donors. www.broad.mit.e...
Broad MOOTHA_PGC View Gene Set 7.621e-06 329 0.0001447 126 Genes up-regulated in differentiating C2C12 cells (myoblasts) upon expression of PPARGC1A [Gene ID=10891] off an adenoviral vector. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN View Gene Set 8.118e-06 46 0.0001529 127 Cluster 6: genes down-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] in combination with serum but not affected by serum alone; they are also up-regulated by MYC alone. www.broad.mit.e...
Broad SEMBA_FHIT_TARGETS_DN View Gene Set 8.923e-06 10 0.0001667 128 Genes down-regulated in H1299 cells (non-small cell lung cancer NSCLC) expressing the Y144F mutant form of FHIT [Gene ID=2272]. www.broad.mit.e...
Broad HESS_TARGETS_OF_HOXA9_AND_MEIS1_UP View Gene Set 1.152e-05 59 0.0002136 129 Genes up-regulated in hematopoietic precursor cells conditionally expressing HOXA9 and MEIS1 [Gene ID=3205 4211]. www.broad.mit.e...
Broad CAFFAREL_RESPONSE_TO_THC_DN View Gene Set 1.182e-05 25 0.0002174 130 Genes down-regulated in EVSA-T cells (breast cancer) treated THC (delta-9-tetrahydrocannabinol) [PubChem=6610319]. www.broad.mit.e...
Broad SMID_BREAST_CANCER_LUMINAL_A_DN View Gene Set 1.65e-05 17 0.0003013 131 Genes down-regulated in the luminal A subtype of breast cancer. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP View Gene Set 2.039e-05 52 0.0003695 132 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G23 defined by unsupervised clustering. www.broad.mit.e...
Broad GOLDRATH_HOMEOSTATIC_PROLIFERATION View Gene Set 2.345e-05 154 0.0004217 133 Up-regulated in CD8+ [Gene ID=925] T lymphocytes undergoing homeostatic proliferation (HP) versus the naive cells; these genes are not up-regulated versus effector or memory cell population. www.broad.mit.e...
Broad SU_TESTIS View Gene Set 2.374e-05 75 0.0004237 134 Genes up-regulated specifically in human testis tissue. www.broad.mit.e...
Broad CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP View Gene Set 4.198e-05 47 0.0007438 135 Genes up-regulated by 2-methoxyestradiol (2ME2) [PubChem=1573] in the MM.1S cell line (multiple myeloma) sensitive to dexamethasone [PubChem=5743]. www.broad.mit.e...
Broad NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP View Gene Set 4.717e-05 87 0.0008296 136 Top 100 probe sets contrubuting to the positive side of the 2nd principal component; associated with adipocytic differentiation. www.broad.mit.e...
Broad CHANG_CORE_SERUM_RESPONSE_UP View Gene Set 5.13e-05 66 0.0008957 137 Up-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group. www.broad.mit.e...
Broad BHATTACHARYA_EMBRYONIC_STEM_CELL View Gene Set 6.187e-05 76 0.001072 138 The 'stemnes' signature: genes up-regulated and common to 6 human embryonic stem cell lines tested. www.broad.mit.e...
Broad FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN View Gene Set 6.491e-05 76 0.001117 139 Top 100 genes positively (UP) and negatively (DN) associated with T-cell acute lymphoblastic leukemia MLL T-ALL) expressing MLL-ENL fusion [Gene ID=4297 4298]. www.broad.mit.e...
Broad MATTIOLI_MGUS_VS_PCL View Gene Set 8.7e-05 109 0.001486 140 Genes changed in MGUS (monoclonal gammopathy of undetermined significance) compared to PCL (plasma cell leukemia) samples. www.broad.mit.e...
Broad MENSSEN_MYC_TARGETS View Gene Set 9.306e-05 16 0.001579 141 Genes up-regulated by adenoviral expression of c-MYC [Gene ID=4609] in HUVEC cells (umbilical vein endothelium). www.broad.mit.e...
Broad MOOTHA_VOXPHOS View Gene Set 0.0001003 82 0.00169 142 Genes involved in oxidative phosphorylation; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. www.broad.mit.e...
Broad STEIN_ESRRA_TARGETS_UP View Gene Set 0.0001025 368 0.001715 143 Genes up-regulated by ESRRA [Gene ID=2101] only. www.broad.mit.e...
Broad CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN View Gene Set 0.000109 155 0.00181 144 Marker genes down-regulated in the 'unannotated' subclass of hepatocellular carcinoma (HCC) samples. www.broad.mit.e...
Broad BENPORATH_MYC_TARGETS_WITH_EBOX View Gene Set 0.0001245 229 0.002054 145 Set 'Myc targets1': targets of c-Myc [Gene ID=4609] identified by ChIP on chip in cultured cell lines focusing on E-box???containing genes; high affinity bound subset www.broad.mit.e...
Broad LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN View Gene Set 0.0001401 742 0.002295 146 Genes with copy number losses in primary neuroblastoma tumors. www.broad.mit.e...
Broad LIU_SOX4_TARGETS_DN View Gene Set 0.0001546 297 0.002515 147 Genes down-regulated in LNCaP cells (prostate cancer) by overexpression of SOX4 [Gene ID=6659] and up-regulated by its RNAi knockdown. www.broad.mit.e...
Broad ZHAN_MULTIPLE_MYELOMA_SUBGROUPS View Gene Set 0.000204 28 0.003297 148 Top genes up-regulated in MM4 vs MM1 subgroup of multiple myeloma samples. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN View Gene Set 0.0002054 160 0.003298 149 Genes down-regulated in metastatic breast cancer tumors having type 2 amplification in the 20q13 region; involves MYBL2 STK6 and ZNF217 [Gene ID=4605 6790 7764] www.broad.mit.e...
Broad MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP View Gene Set 0.0002382 359 0.003799 150 The postradiation tumor escape signature: genes up-regulated in tumors from irradiated stroma vs those from non-irradiated stroma. www.broad.mit.e...
Broad HOSHIDA_LIVER_CANCER_SUBCLASS_S2 View Gene Set 0.0002614 114 0.004141 151 Genes from 'subtype S2' signature of hepatocellular carcinoma (HCC): proliferation MYC and AKT1 [Gene ID=4609 207] activation. www.broad.mit.e...
Broad GOLDRATH_ANTIGEN_RESPONSE View Gene Set 0.0002725 315 0.004289 152 Genes up-regulated at the peak of an antigen response of naive CD8+ [Gene ID=925 926] T-cells. www.broad.mit.e...
Broad GALE_APL_WITH_FLT3_MUTATED_UP View Gene Set 0.0002836 52 0.004433 153 Genes up-regulated in acute promyelocytic leukemia (APL) patients with mutated FLT3 [Gene ID=2322]. www.broad.mit.e...
Broad BORCZUK_MALIGNANT_MESOTHELIOMA_UP View Gene Set 0.0003316 290 0.005151 154 Genes up-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma. www.broad.mit.e...
Broad PENG_GLUTAMINE_DEPRIVATION_DN View Gene Set 0.0003401 84 0.005249 155 Genes down-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation. www.broad.mit.e...
Broad GRADE_METASTASIS_DN View Gene Set 0.0003452 44 0.005294 156 Down-regulated genes in colon carcinoma tumors with lymph node metastases. www.broad.mit.e...
Broad KIM_WT1_TARGETS_DN View Gene Set 0.0003881 431 0.005913 157 Genes down-regulated in UB27 cells (osteosarcoma) at any time point after inducing the expression of a mutant form of WT1 [Gene ID=7490]. www.broad.mit.e...
Broad CAMPS_COLON_CANCER_COPY_NUMBER_UP View Gene Set 0.0004696 75 0.007109 158 Genes from chromosomal copy number gains in a panel of 51 primary colon carcinoma samples. www.broad.mit.e...
Broad BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP View Gene Set 0.0005063 190 0.007524 159 Genes up-regulated in medullary breast cancer (MBC) relative to ductal breast cancer (DBD). www.broad.mit.e...
Broad FOURNIER_ACINAR_DEVELOPMENT_LATE_DN View Gene Set 0.0005037 21 0.007524 159 Genes down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro. www.broad.mit.e...
Broad BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN View Gene Set 0.0005064 599 0.007524 159 Genes down-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress. www.broad.mit.e...
Broad UDAYAKUMAR_MED1_TARGETS_UP View Gene Set 0.000517 129 0.007634 162 Genes up-regulated in HeLa cells after knockdown of MED1 [Gene ID=5469] by RNAi. www.broad.mit.e...
Broad ELVIDGE_HIF1A_TARGETS_UP View Gene Set 0.0005277 64 0.007744 163 Genes up-regulated in MCF7 cells (breast cancer) after knockdown of HIF1A [Gene ID=3091] by RNAi. www.broad.mit.e...
Broad RIZ_ERYTHROID_DIFFERENTIATION_CCNE1 View Gene Set 0.0005935 38 0.008572 164 Selected gradually up-regulated genes whose expression profile follows that of CCNE1 [Gene ID=898] in the TLX1 [Gene ID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP View Gene Set 0.0005997 36 0.008572 164 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_DN View Gene Set 0.0005997 36 0.008572 164 Down-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors. www.broad.mit.e...
Broad STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN View Gene Set 0.000602 437 0.008572 164 Genes down-regulated in prefrontal cortex (PFC) of mice carrying a hemizygotic microdeletion in the 22q11.2 region. www.broad.mit.e...
Broad LEE_METASTASIS_AND_RNA_PROCESSING_UP View Gene Set 0.000589 15 0.008572 164 Components of RNA post-transcriptional modification machinery up-regulated in MDA-MB-435 cells (breast cancer) whose metastatic potential has been reduced by expression of NME1 [Gene ID=4830]. www.broad.mit.e...
Broad CHUANG_OXIDATIVE_STRESS_RESPONSE_DN View Gene Set 0.0006658 10 0.009423 169 Genes down-regulated in MCF7 cells (breast cancer) after treatment with the oxydants: hydrogen peroxyde menadione and t-butyl hydroperoxyde [PubChem=784 4055 6410]. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP View Gene Set 0.0008455 220 0.0119 170 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors. www.broad.mit.e...
Broad DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2 View Gene Set 0.0009993 111 0.01398 171 'Cancer prone response profile' (CPRP): genes common to estradiol and bisphenol A [PubChem=5757 6623] response of epithelial cell cultures from patients at high risk of breast cancer. www.broad.mit.e...
Broad DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER View Gene Set 0.001063 91 0.01478 172 The lung adenocarcinoma TSP (tumor sequencing project) genes showing strong correlation between DNA copy number variation and gene expression. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 View Gene Set 0.001154 158 0.01596 173 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 13. www.broad.mit.e...
Broad GAJATE_RESPONSE_TO_TRABECTEDIN_DN View Gene Set 0.001177 16 0.01619 174 Genes down-regulated in HeLa cells (cervical carcinoma) by trabectedin [PubChem=3199]. www.broad.mit.e...
Broad CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN View Gene Set 0.001229 81 0.0168 175 Genes down-regulated in ANBL-6 cell line (multiple myeloma MM) expressing an activated form of NRAS [Gene ID=4893] off a plasmid vector compared to those co-cultured with bone marrow stromal cells. www.broad.mit.e...
Broad SHEPARD_BMYB_TARGETS View Gene Set 0.00128 60 0.01739 176 Human orthologs of BMYB [Gene ID=4605] target genes in zebra fish identified as commonly changed in the BMYB loss of function mutant crb ('crush and burn') and after knockdown of BMYB by morpholino. www.broad.mit.e...
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_DN View Gene Set 0.001338 24 0.01808 177 Genes from the green module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC). www.broad.mit.e...
Broad RASHI_RESPONSE_TO_IONIZING_RADIATION_4 View Gene Set 0.001396 48 0.01876 178 Cluster 4: genes repressed by ionizing radiation regardless of ATM [Gene ID=472] status. www.broad.mit.e...
Broad MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN View Gene Set 0.00158 212 0.02112 179 Genes down-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199]. www.broad.mit.e...
Broad LOPEZ_MBD_TARGETS View Gene Set 0.001607 855 0.02136 180 Genes up-regulated in HeLa cells (cervical cancer) after simultaneus knockdown of all three MBD (methyl-CpG binding domain) proteins MeCP2 MBD1 and MBD2 [Gene ID=4204 4152 8932] by RNAi. www.broad.mit.e...
Broad VANTVEER_BREAST_CANCER_METASTASIS_DN View Gene Set 0.001621 104 0.02143 181 Genes whose expression is significantly and negatively correlated with poor breast cancer clinical outcome (defined as developing distant metastases in less than 5 years). www.broad.mit.e...
Broad LINDGREN_BLADDER_CANCER_CLUSTER_1_DN View Gene Set 0.001906 368 0.02491 182 Genes whose expression profile is specific to Custer I of urothelial cell carcinoma (UCC) tumors. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP View Gene Set 0.001896 44 0.02491 182 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G123 defined by unsupervised clustering. www.broad.mit.e...
Broad GEORGES_CELL_CYCLE_MIR192_TARGETS View Gene Set 0.002194 59 0.02852 184 Experimentally validated direct targets of MIR192 [Gene ID=406967] microRNA; MIR192 caused cell cycle arrest in HCT116 cells (colon cancer). www.broad.mit.e...
Broad GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP View Gene Set 0.002244 86 0.0287 185 Genes up-regulated in quiescent (G0) CD34+ [Gene ID=8842] cells isolated from peripheral blood of CML (chronic myeloid leukemia) patients compared to the quiescent cells from normal donors. www.broad.mit.e...
Broad MEINHOLD_OVARIAN_CANCER_LOW_GRADE_DN View Gene Set 0.002229 18 0.0287 185 Genes down-regulated in low grade (LMP and G1) serous ovarian carcinomas vs the higher grade invasive tumors (G2 and G3). www.broad.mit.e...
Broad BASSO_B_LYMPHOCYTE_NETWORK View Gene Set 0.002236 136 0.0287 185 Genes which comprise the top 1% of highly interconnected genes (major hubs) that account for most of gene interactions in the reconstructed regulatory networks from expression profiles in B lymphocytes. www.broad.mit.e...
Broad WILCOX_PRESPONSE_TO_ROGESTERONE_UP View Gene Set 0.002288 143 0.02911 188 Genes up-regulated in primary cultures of ovarian surface epithlium cells exposed to progesterone [PubChem=5994] for 5 days. www.broad.mit.e...
Broad GAL_LEUKEMIC_STEM_CELL_DN View Gene Set 0.002307 239 0.0292 189 Genes down-regulated in leukemic stem cells (LSC) defined as CD34+CD38- [Gene ID=947 952] cells from AML (acute myeloid leukemia patients) compared to the CD34+CD38+ cells. www.broad.mit.e...
Broad NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON View Gene Set 0.002409 150 0.03033 190 Genes within amplicon 8q23-q24 identified in a copy number alterations study of 191 breast tumor samples. www.broad.mit.e...
Broad ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP View Gene Set 0.002726 806 0.03414 191 Genes up-regulated in liver tumor compared to the normal adjacent tissue. www.broad.mit.e...
Broad MANN_RESPONSE_TO_AMIFOSTINE_DN View Gene Set 0.002803 9 0.03492 192 Genes down-regulated in HCT116 cells (colon cancer) after treatment with amifostine [PubChem=2141] depending on the presence of TP53 [Gene ID=7157]: TP53-positive vs TP53-null cells. www.broad.mit.e...
Broad BILD_MYC_ONCOGENIC_SIGNATURE View Gene Set 0.002913 187 0.0361 193 Genes selected in supervised analyses to discriminate cells expressing c-Myc [Gene ID=4609] from control cells expressing GFP. www.broad.mit.e...
Broad WALLACE_JAK2_TARGETS_UP View Gene Set 0.00316 21 0.03896 194 Genes changed more than 7-fold by expressing JAK2 [Gene ID=3717] in the JAK2 null cell line. www.broad.mit.e...
Broad ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_DN View Gene Set 0.003533 17 0.04334 195 Genes in discrete regions of loss within 16q region detected in individual invasive breast cancer tumors. www.broad.mit.e...
Broad KALMA_E2F1_TARGETS View Gene Set 0.003627 11 0.04404 196 DNA replication genes up-regulated in a Rat-1a cell line (fibroblast) by expression of E2F1 [Gene ID=1869]. www.broad.mit.e...
Broad JISON_SICKLE_CELL_DISEASE_DN View Gene Set 0.003614 168 0.04404 196 Genes down-regulated in peripheral blood mononuclear cells (PBMC) from sickle cell disease patients compared to those from healthy subjects. www.broad.mit.e...
Broad MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP View Gene Set 0.00372 92 0.04477 198 Genes correlated with the early tumor onset in the Emu-myc transgenic mouse lymphoma model. www.broad.mit.e...
Broad LIN_APC_TARGETS View Gene Set 0.003725 52 0.04477 198 Genes up-regulated by forced expression of APC [Gene ID=324] in the APC-deficient SW480 cell line (colon cancer). www.broad.mit.e...
Broad MODY_HIPPOCAMPUS_PRENATAL View Gene Set 0.003891 27 0.04653 200 Genes highly expressed in prenatal hippocampus (cluster 1). www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.BIOCARTA

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad BIOCARTA_ATRBRCA_PATHWAY View Gene Set 1.018e-06 21 0.0001454 1 Role of BRCA1 BRCA2 and ATR in Cancer Susceptibility www.broad.mit.e...
Broad BIOCARTA_RANMS_PATHWAY View Gene Set 1.34e-06 10 0.0001454 1 Role of Ran in mitotic spindle regulation www.broad.mit.e...
Broad BIOCARTA_SRCRPTP_PATHWAY View Gene Set 0.001301 11 0.04707 3 Activation of Src by Protein-tyrosine phosphatase alpha www.broad.mit.e...
Broad BIOCARTA_DNAFRAGMENT_PATHWAY View Gene Set 0.001233 10 0.04707 3 Apoptotic DNA fragmentation and tissue homeostasis www.broad.mit.e...
Broad BIOCARTA_G2_PATHWAY View Gene Set 0.001186 24 0.04707 3 Cell Cycle: G2/M Checkpoint www.broad.mit.e...
Broad BIOCARTA_PTC1_PATHWAY View Gene Set 0.0009022 11 0.04707 3 Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.KEGG

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad KEGG_SPLICEOSOME View Gene Set 1.355e-13 118 2.52e-11 1 Spliceosome www.broad.mit.e...
Broad KEGG_CELL_CYCLE View Gene Set 1.692e-07 128 1.574e-05 2 Cell cycle www.broad.mit.e...
Broad KEGG_PROTEASOME View Gene Set 1.528e-06 48 9.474e-05 3 Proteasome www.broad.mit.e...
Broad KEGG_PYRIMIDINE_METABOLISM View Gene Set 4.463e-06 98 0.000166 4 Pyrimidine metabolism www.broad.mit.e...
Broad KEGG_AMINOACYL_TRNA_BIOSYNTHESIS View Gene Set 3.673e-06 41 0.000166 4 Aminoacyl-tRNA biosynthesis www.broad.mit.e...
Broad KEGG_RNA_DEGRADATION View Gene Set 9.206e-06 59 0.0002446 6 RNA degradation www.broad.mit.e...
Broad KEGG_HOMOLOGOUS_RECOMBINATION View Gene Set 8.323e-06 28 0.0002446 6 Homologous recombination www.broad.mit.e...
Broad KEGG_MISMATCH_REPAIR View Gene Set 4.218e-05 23 0.0009806 8 Mismatch repair www.broad.mit.e...
Broad KEGG_HUNTINGTONS_DISEASE View Gene Set 9.166e-05 185 0.001894 9 Huntington's disease www.broad.mit.e...
Broad KEGG_RNA_POLYMERASE View Gene Set 0.0001784 29 0.003318 10 RNA polymerase www.broad.mit.e...
Broad KEGG_DNA_REPLICATION View Gene Set 0.0002105 36 0.003559 11 DNA replication www.broad.mit.e...
Broad KEGG_PARKINSONS_DISEASE View Gene Set 0.0003035 133 0.004704 12 Parkinson's disease www.broad.mit.e...
Broad KEGG_NUCLEOTIDE_EXCISION_REPAIR View Gene Set 0.000344 44 0.004922 13 Nucleotide excision repair www.broad.mit.e...
Broad KEGG_BASE_EXCISION_REPAIR View Gene Set 0.00128 35 0.017 14 Base excision repair www.broad.mit.e...
Broad KEGG_CITRATE_CYCLE_TCA_CYCLE View Gene Set 0.003462 32 0.04293 15 Citrate cycle (TCA cycle) www.broad.mit.e...
Broad KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS View Gene Set 0.003717 11 0.04321 16 Valine leucine and isoleucine biosynthesis www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.REACTOME

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad REACTOME_CELL_CYCLE_MITOTIC View Gene Set 1.882e-40 306 8.091e-38 1 Genes involved in Cell Cycle Mitotic www.broad.mit.e...
Broad REACTOME_MITOTIC_M_M_G1_PHASES View Gene Set 2.658e-31 157 5.714e-29 2 Genes involved in Mitotic M-M/G1 phases www.broad.mit.e...
Broad REACTOME_MITOTIC_PROMETAPHASE View Gene Set 3.76e-21 92 5.39e-19 3 Genes involved in Mitotic Prometaphase www.broad.mit.e...
Broad REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA View Gene Set 5.329e-21 128 5.729e-19 4 Genes involved in Processing of Capped Intron-Containing Pre-mRNA www.broad.mit.e...
Broad REACTOME_GENE_EXPRESSION View Gene Set 7.11e-20 415 6.115e-18 5 Genes involved in Gene Expression www.broad.mit.e...
Broad REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS View Gene Set 4.706e-18 124 3.372e-16 6 Genes involved in Elongation and Processing of Capped Transcripts www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING View Gene Set 1.133e-16 97 6.96e-15 7 Genes involved in mRNA Splicing www.broad.mit.e...
Broad REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT View Gene Set 1.43e-15 142 7.688e-14 8 Genes involved in Formation and Maturation of mRNA Transcript www.broad.mit.e...
Broad REACTOME_CELL_CYCLE_CHECKPOINTS View Gene Set 4.2e-15 110 2.007e-13 9 Genes involved in Cell Cycle Checkpoints www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_RNA View Gene Set 1.665e-13 95 7.161e-12 10 Genes involved in Metabolism of RNA www.broad.mit.e...
Broad REACTOME_G2_M_TRANSITION View Gene Set 5.659e-12 84 2.212e-10 11 Genes involved in G2/M Transition www.broad.mit.e...
Broad REACTOME_G2_M_CHECKPOINTS View Gene Set 6.388e-12 43 2.289e-10 12 Genes involved in G2/M Checkpoints www.broad.mit.e...
Broad REACTOME_G1_S_TRANSITION View Gene Set 1.101e-11 102 3.641e-10 13 Genes involved in G1/S Transition www.broad.mit.e...
Broad REACTOME_HIV_INFECTION View Gene Set 1.51e-11 183 4.639e-10 14 Genes involved in HIV Infection www.broad.mit.e...
Broad REACTOME_M_G1_TRANSITION View Gene Set 1.111e-10 61 3.186e-09 15 Genes involved in M/G1 Transition www.broad.mit.e...
Broad REACTOME_DNA_REPLICATION_PRE_INITIATION View Gene Set 1.243e-10 76 3.342e-09 16 Genes involved in DNA Replication Pre-Initiation www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS View Gene Set 1.432e-10 37 3.622e-09 17 Genes involved in Activation of ATR in response to replication stress www.broad.mit.e...
Broad REACTOME_SYNTHESIS_OF_DNA View Gene Set 1.772e-10 89 4.234e-09 18 Genes involved in Synthesis of DNA www.broad.mit.e...
Broad REACTOME_DNA_REPAIR View Gene Set 3.113e-10 102 7.046e-09 19 Genes involved in DNA Repair www.broad.mit.e...
Broad REACTOME_CENTROSOME_MATURATION View Gene Set 4.83e-10 72 1.039e-08 20 Genes involved in Centrosome maturation www.broad.mit.e...
Broad REACTOME_S_PHASE View Gene Set 6.191e-10 103 1.268e-08 21 Genes involved in S Phase www.broad.mit.e...
Broad REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX View Gene Set 9.255e-10 52 1.809e-08 22 Genes involved in CDT1 association with the CDC6:ORC:origin complex www.broad.mit.e...
Broad REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS View Gene Set 1.113e-09 120 2.08e-08 23 Genes involved in Host Interactions of HIV factors www.broad.mit.e...
Broad REACTOME_SNRNP_ASSEMBLY View Gene Set 6.938e-09 50 1.243e-07 24 Genes involved in snRNP Assembly www.broad.mit.e...
Broad REACTOME_REGULATION_OF_APC_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE View Gene Set 1.213e-08 71 2.087e-07 25 Genes involved in Regulation of APC/C activators between G1/S and early anaphase www.broad.mit.e...
Broad REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES View Gene Set 1.592e-08 62 2.633e-07 26 Genes involved in Loss of Nlp from mitotic centrosomes www.broad.mit.e...
Broad REACTOME_ORC1_REMOVAL_FROM_CHROMATIN View Gene Set 1.695e-08 63 2.699e-07 27 Genes involved in Orc1 removal from chromatin www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRON_CONTAINING_TRANSCRIPT View Gene Set 2.178e-08 42 3.345e-07 28 Genes involved in Transport of Mature mRNA derived from an Intron-Containing Transcript www.broad.mit.e...
Broad REACTOME_CDC20_PHOSPHO_APC_MEDIATED_DEGRADATION_OF_CYCLIN_A View Gene Set 2.944e-08 63 4.366e-07 29 Genes involved in Cdc20:Phospho-APC/C mediated degradation of Cyclin A www.broad.mit.e...
Broad REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 View Gene Set 1.32e-07 48 1.892e-06 30 Genes involved in SCF-beta-TrCP mediated degradation of Emi1 www.broad.mit.e...
Broad REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC View Gene Set 1.384e-07 57 1.919e-06 31 Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C www.broad.mit.e...
Broad REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE View Gene Set 3.97e-07 43 5.334e-06 32 Genes involved in p53-Independent DNA Damage Response www.broad.mit.e...
Broad REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN View Gene Set 4.679e-07 30 6.096e-06 33 Genes involved in Nuclear import of Rev protein www.broad.mit.e...
Broad REACTOME_REV_MEDIATED_NUCLEAR_EXPORT_OF_HIV1_RNA View Gene Set 7.18e-07 31 9.081e-06 34 Genes involved in Rev-mediated nuclear export of HIV-1 RNA www.broad.mit.e...
Broad REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G View Gene Set 8.239e-07 47 1.012e-05 35 Genes involved in Vif-mediated degradation of APOBEC3G www.broad.mit.e...
Broad REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE View Gene Set 8.654e-07 90 1.034e-05 36 Genes involved in Late Phase of HIV Life Cycle www.broad.mit.e...
Broad REACTOME_HIV_LIFE_CYCLE View Gene Set 9.678e-07 103 1.125e-05 37 Genes involved in HIV Life Cycle www.broad.mit.e...
Broad REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY View Gene Set 1.583e-06 29 1.792e-05 38 Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_MRNA View Gene Set 2.267e-06 45 2.5e-05 39 Genes involved in Metabolism of mRNA www.broad.mit.e...
Broad REACTOME_STABILIZATION_OF_P53 View Gene Set 2.433e-06 46 2.615e-05 40 Genes involved in Stabilization of p53 www.broad.mit.e...
Broad REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE View Gene Set 2.584e-06 47 2.71e-05 41 Genes involved in Regulation of ornithine decarboxylase (ODC) www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS View Gene Set 3.006e-06 29 3.078e-05 42 Genes involved in Transport of Ribonucleoproteins into the Host Nucleus www.broad.mit.e...
Broad REACTOME_SIGNALING_BY_WNT View Gene Set 3.301e-06 58 3.301e-05 43 Genes involved in Signaling by Wnt www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION View Gene Set 4.23e-06 83 4.134e-05 44 Genes involved in RNA Polymerase II Transcription www.broad.mit.e...
Broad REACTOME_MRNA_3_END_PROCESSING View Gene Set 4.666e-06 25 4.459e-05 45 Genes involved in mRNA 3-end processing www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING_MINOR_PATHWAY View Gene Set 6.432e-06 38 6.013e-05 46 Genes involved in mRNA Splicing - Minor Pathway www.broad.mit.e...
Broad REACTOME_TRNA_AMINOACYLATION View Gene Set 8.122e-06 40 7.431e-05 47 Genes involved in tRNA Aminoacylation www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_THE_SLBP_INDEPENDENT_MATURE_MRNA View Gene Set 1.037e-05 32 9.293e-05 48 Genes involved in Transport of the SLBP independent Mature mRNA www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION_COUPLED_NER View Gene Set 1.302e-05 44 0.0001142 49 Genes involved in Transcription-coupled NER (TC-NER) www.broad.mit.e...
Broad REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN View Gene Set 1.388e-05 29 0.0001193 50 Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein www.broad.mit.e...
Broad REACTOME_NUCLEOTIDE_EXCISION_REPAIR View Gene Set 3.593e-05 49 0.0003029 51 Genes involved in Nucleotide Excision Repair www.broad.mit.e...
Broad REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION View Gene Set 3.692e-05 20 0.0003053 52 Genes involved in Mitochondrial tRNA aminoacylation www.broad.mit.e...
Broad REACTOME_VPR_MEDIATED_NUCLEAR_IMPORT_OF_PICS View Gene Set 4.081e-05 31 0.0003311 53 Genes involved in Vpr-mediated nuclear import of PICs www.broad.mit.e...
Broad REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21 View Gene Set 4.339e-05 52 0.0003455 54 Genes involved in SCF(Skp2)-mediated degradation of p2721 www.broad.mit.e...
Broad REACTOME_DNA_STRAND_ELONGATION View Gene Set 7.52e-05 31 0.0005879 55 Genes involved in DNA strand elongation www.broad.mit.e...
Broad REACTOME_CYCLIN_A1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION View Gene Set 7.863e-05 15 0.0005913 56 Genes involved in Cyclin A1 associated events during G2/M transition www.broad.mit.e...
Broad REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION View Gene Set 7.713e-05 33 0.0005913 56 Genes involved in E2F mediated regulation of DNA replication www.broad.mit.e...
Broad REACTOME_E2F_TRANSCRIPTIONAL_TARGETS_AT_G1_S View Gene Set 7.975e-05 22 0.0005913 56 Genes involved in E2F transcriptional targets at G1/S www.broad.mit.e...
Broad REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ View Gene Set 8.22e-05 58 0.0005991 59 Genes involved in Cyclin E associated events during G1/S transition www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX View Gene Set 0.0001002 30 0.0007179 60 Genes involved in Activation of the pre-replicative complex www.broad.mit.e...
Broad REACTOME_GLUCOSE_TRANSPORT View Gene Set 0.0001024 38 0.0007221 61 Genes involved in Glucose transport www.broad.mit.e...
Broad REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION View Gene Set 0.0001093 161 0.0007578 62 Genes involved in Glucose Regulation of Insulin Secretion www.broad.mit.e...
Broad REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION View Gene Set 0.0001412 10 0.0009637 63 Genes involved in E2F-enabled inhibition of pre-replication complex formation www.broad.mit.e...
Broad REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE View Gene Set 0.0001474 11 0.0009905 64 Genes involved in mRNA Decay by 3' to 5' Exoribonuclease www.broad.mit.e...
Broad REACTOME_DOUBLE_STRAND_BREAK_REPAIR View Gene Set 0.0001557 21 0.00103 65 Genes involved in Double-Strand Break Repair www.broad.mit.e...
Broad REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC View Gene Set 0.0001677 22 0.001092 66 Genes involved in Formation of tubulin folding intermediates by CCT/TriC www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION View Gene Set 0.0001717 188 0.001102 67 Genes involved in Transcription www.broad.mit.e...
Broad REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY View Gene Set 0.0002064 19 0.001305 68 Genes involved in Post-chaperonin tubulin folding pathway www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_PROTEINS View Gene Set 0.0002215 215 0.00138 69 Genes involved in Metabolism of proteins www.broad.mit.e...
Broad REACTOME_INFLUENZA_LIFE_CYCLE View Gene Set 0.0002701 137 0.001659 70 Genes involved in Influenza Life Cycle www.broad.mit.e...
Broad REACTOME_EXTENSION_OF_TELOMERES View Gene Set 0.0002931 28 0.001751 71 Genes involved in Extension of Telomeres www.broad.mit.e...
Broad REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES View Gene Set 0.0002912 11 0.001751 71 Genes involved in Recruitment of NuMA to mitotic centrosomes www.broad.mit.e...
Broad REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR View Gene Set 0.0003034 15 0.001787 73 Genes involved in Homologous Recombination Repair www.broad.mit.e...
Broad REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING View Gene Set 0.0003977 50 0.002311 74 Genes involved in Chaperonin-mediated protein folding www.broad.mit.e...
Broad REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC View Gene Set 0.0004127 28 0.002366 75 Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC www.broad.mit.e...
Broad REACTOME_MICRORNA_BIOGENESIS View Gene Set 0.0005554 18 0.003143 76 Genes involved in MicroRNA biogenesis www.broad.mit.e...
Broad REACTOME_FORMATION_OF_THE_EARLY_ELONGATION_COMPLEX View Gene Set 0.0005711 32 0.003189 77 Genes involved in Formation of the Early Elongation Complex www.broad.mit.e...
Broad REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC:ORIGIN_COMPLEX View Gene Set 0.0006225 11 0.003432 78 Genes involved in CDC6 association with the ORC:origin complex www.broad.mit.e...
Broad REACTOME_CITRIC_ACID_CYCLE View Gene Set 0.0006453 19 0.003513 79 Genes involved in Citric acid cycle (TCA cycle) www.broad.mit.e...
Broad REACTOME_TRANSLATION View Gene Set 0.0006553 120 0.003522 80 Genes involved in Translation www.broad.mit.e...
Broad REACTOME_UNWINDING_OF_DNA View Gene Set 0.0006963 11 0.003697 81 Genes involved in Unwinding of DNA www.broad.mit.e...
Broad REACTOME_HIV1_TRANSCRIPTION_ELONGATION View Gene Set 0.0007862 41 0.004123 82 Genes involved in HIV-1 Transcription Elongation www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_CARBOHYDRATES View Gene Set 0.0008143 119 0.004219 83 Genes involved in Metabolism of carbohydrates www.broad.mit.e...
Broad REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PREREPLICATIVE_COMPLEX View Gene Set 0.0009716 12 0.004974 84 Genes involved in Association of licensing factors with the pre-replicative complex www.broad.mit.e...
Broad REACTOME_APOPTOSIS View Gene Set 0.001059 129 0.005356 85 Genes involved in Apoptosis www.broad.mit.e...
Broad REACTOME_FANCONI_ANEMIA_PATHWAY View Gene Set 0.001174 15 0.005869 86 Genes involved in Fanconi Anemia pathway www.broad.mit.e...
Broad REACTOME_TELOMERE_MAINTENANCE View Gene Set 0.00156 77 0.00771 87 Genes involved in Telomere Maintenance www.broad.mit.e...
Broad REACTOME_DUAL_INCISION_REACTION_IN_TC_NER View Gene Set 0.001676 28 0.008188 88 Genes involved in Dual incision reaction in TC-NER www.broad.mit.e...
Broad REACTOME_GLOBAL_GENOMIC_NER View Gene Set 0.001955 33 0.009448 89 Genes involved in Global Genomic NER (GG-NER) www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_AMINO_ACIDS View Gene Set 0.002628 162 0.0125 90 Genes involved in Metabolism of amino acids www.broad.mit.e...
Broad REACTOME_DEADENYLATION_OF_MRNA View Gene Set 0.002645 21 0.0125 90 Genes involved in Deadenylation of mRNA www.broad.mit.e...
Broad REACTOME_REPAIR_SYNTHESIS_OF_PATCH_27_30_BASES_LONG_BY_DNA_POLYMERASE View Gene Set 0.003025 15 0.01414 92 Genes involved in Repair synthesis of patch ~27-30 bases long by DNA polymerase www.broad.mit.e...
Broad REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION View Gene Set 0.003197 23 0.01478 93 Genes involved in Cytosolic tRNA aminoacylation www.broad.mit.e...
Broad REACTOME_TAT_MEDIATED_HIV1_ELONGATION_ARREST_AND_RECOVERY View Gene Set 0.003371 30 0.01542 94 Genes involved in Tat-mediated HIV-1 elongation arrest and recovery www.broad.mit.e...
Broad REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT View Gene Set 0.003668 23 0.0166 95 Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat www.broad.mit.e...
Broad REACTOME_INTEGRATION_OF_ENERGY_METABOLISM View Gene Set 0.004159 229 0.01863 96 Genes involved in Integration of energy metabolism www.broad.mit.e...
Broad REACTOME_MTORC1_MEDIATED_SIGNALLING View Gene Set 0.004606 11 0.02021 97 Genes involved in mTORC1-mediated signalling www.broad.mit.e...
Broad REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION View Gene Set 0.004561 56 0.02021 97 Genes involved in Translation initiation complex formation www.broad.mit.e...
Broad REACTOME_APCDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B View Gene Set 0.004906 18 0.02131 99 Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B www.broad.mit.e...
Broad REACTOME_ELECTRON_TRANSPORT_CHAIN View Gene Set 0.00497 75 0.02137 100 Genes involved in Electron Transport Chain www.broad.mit.e...
Broad REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT View Gene Set 0.005023 106 0.02139 101 Genes involved in GTP hydrolysis and joining of the 60S ribosomal subunit www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME View Gene Set 0.007583 59 0.03197 102 Genes involved in Transcription of the HIV genome www.broad.mit.e...
Broad REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX View Gene Set 0.007736 49 0.03214 103 Genes involved in Formation of the ternary complex and subsequently the 43S complex www.broad.mit.e...
Broad REACTOME_PHOSPHORYLATION_OF_THE_APC View Gene Set 0.007772 17 0.03214 103 Genes involved in Phosphorylation of the APC/C www.broad.mit.e...
Broad REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM View Gene Set 0.00846 17 0.03464 105 Genes involved in Branched-chain amino acid catabolism www.broad.mit.e...
Broad REACTOME_METABLISM_OF_NUCLEOTIDES View Gene Set 0.009929 71 0.04028 106 Genes involved in Metablism of nucleotides www.broad.mit.e...
Broad REACTOME_LAGGING_STRAND_SYNTHESIS View Gene Set 0.01043 20 0.04192 107 Genes involved in Lagging Strand Synthesis www.broad.mit.e...
Broad REACTOME_REGULATION_OF_INSULIN_SECRETION View Gene Set 0.0116 212 0.04618 108 Genes involved in Regulation of Insulin Secretion www.broad.mit.e...
Broad REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND View Gene Set 0.01185 10 0.04675 109 Genes involved in Removal of the Flap Intermediate from the C-strand www.broad.mit.e...
Broad REACTOME_INACTIVATION_OF_APC_VIA_DIRECT_INHIBITION_OF_THE_APCOMPLEX View Gene Set 0.01209 18 0.04726 110 Genes involved in Inactivation of APC/C via direct inhibition of the APC/C complex www.broad.mit.e...

Gene Set Collection: Broad.c3.TFT

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad SCGGAAGY_V$ELK1_02 View Gene Set 2.411e-08 784 1.483e-05 1 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SCGGAAGY which matches annotation for ELK1: ELK1 member of ETS oncogene family www.broad.mit.e...
Broad V$E2F_Q4 View Gene Set 1.932e-06 166 0.0005942 2 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F_Q6 View Gene Set 7.862e-06 165 0.001209 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F_Q4_01 View Gene Set 6.68e-06 171 0.001209 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCSCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1DP1RB_01 View Gene Set 1.994e-05 168 0.002044 5 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) www.broad.mit.e...
Broad V$E2F1_Q6_01 View Gene Set 1.912e-05 177 0.002044 5 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTTCGCGCS which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F_Q3_01 View Gene Set 2.612e-05 171 0.002044 7 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1_Q4_01 View Gene Set 2.659e-05 167 0.002044 7 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$MYCMAX_01 View Gene Set 3.342e-05 189 0.002284 9 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNACCACGTGGTNN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X www.broad.mit.e...
Broad CACGTG_V$MYC_Q2 View Gene Set 4.084e-05 734 0.002512 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CACGTG which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian) www.broad.mit.e...
Broad V$E2F_Q6_01 View Gene Set 8.538e-05 167 0.004773 11 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKCGCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad GCCATNTTG_V$YY1_Q6 View Gene Set 9.346e-05 289 0.00479 12 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTG which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad V$E2F_02 View Gene Set 0.0002163 169 0.008638 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1_Q3 View Gene Set 0.0002256 176 0.008638 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKTSSCGC which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F_03 View Gene Set 0.0002809 171 0.008638 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGCGMNR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1DP1_01 View Gene Set 0.0002558 169 0.008638 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1DP2_01 View Gene Set 0.0002558 169 0.008638 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) www.broad.mit.e...
Broad V$E2F4DP1_01 View Gene Set 0.0002779 174 0.008638 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F4DP2_01 View Gene Set 0.0002558 169 0.008638 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) www.broad.mit.e...
Broad SGCGSSAAA_V$E2F1DP2_01 View Gene Set 0.0002453 122 0.008638 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SGCGSSAAA which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) www.broad.mit.e...
Broad V$E2F1_Q6 View Gene Set 0.0003744 167 0.01096 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGS which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$NFMUE1_Q6 View Gene Set 0.0009409 175 0.0263 22 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CGGCCATCT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F_Q3 View Gene Set 0.001403 162 0.03752 23 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTCGCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF2_Q6 View Gene Set 0.001475 182 0.03779 24 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CASGYG. Motif does not match any known transcription factor www.broad.mit.e...

Gene Set Collection: Broad.c4.CGN

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad MORF_BUB3 View Gene Set 1.272e-34 256 5.432e-32 1 Neighborhood of BUB3 www.broad.mit.e...
Broad MORF_EIF3S2 View Gene Set 1.672e-28 220 3.57e-26 2 Neighborhood of EIF3S2 www.broad.mit.e...
Broad MORF_RAD23A View Gene Set 2.218e-27 316 3.157e-25 3 Neighborhood of RAD23A www.broad.mit.e...
Broad GNF2_CDC20 View Gene Set 1.572e-26 52 1.678e-24 4 Neighborhood of CDC20 www.broad.mit.e...
Broad GNF2_CCNB2 View Gene Set 2.516e-26 53 2.149e-24 5 Neighborhood of CCNB2 www.broad.mit.e...
Broad GNF2_RRM1 View Gene Set 8.322e-26 82 5.922e-24 6 Neighborhood of RRM1 www.broad.mit.e...
Broad GNF2_CENPF View Gene Set 6.528e-25 56 3.982e-23 7 Neighborhood of CENPF www.broad.mit.e...
Broad GNF2_CCNA2 View Gene Set 5.689e-23 62 3.037e-21 8 Neighborhood of CCNA2 www.broad.mit.e...
Broad GNF2_PCNA View Gene Set 2.946e-22 62 1.398e-20 9 Neighborhood of PCNA www.broad.mit.e...
Broad MORF_PRKDC View Gene Set 1.977e-21 173 8.44e-20 10 Neighborhood of PRKDC www.broad.mit.e...
Broad GNF2_SMC4L1 View Gene Set 2.589e-21 75 1.005e-19 11 Neighborhood of SMC4L1 www.broad.mit.e...
Broad GNF2_HMMR View Gene Set 4.364e-21 43 1.553e-19 12 Neighborhood of HMMR www.broad.mit.e...
Broad GNF2_CDC2 View Gene Set 1.201e-20 56 3.946e-19 13 Neighborhood of CDC2 www.broad.mit.e...
Broad MORF_DNMT1 View Gene Set 1.272e-19 105 3.88e-18 14 Neighborhood of DNMT1 www.broad.mit.e...
Broad GNF2_RFC4 View Gene Set 3.404e-19 57 9.69e-18 15 Neighborhood of RFC4 www.broad.mit.e...
Broad MORF_RFC4 View Gene Set 7.019e-19 137 1.873e-17 16 Neighborhood of RFC4 www.broad.mit.e...
Broad MORF_UBE2I View Gene Set 2.473e-18 208 6.213e-17 17 Neighborhood of UBE2I www.broad.mit.e...
Broad MORF_FBL View Gene Set 3.082e-18 121 7.312e-17 18 Neighborhood of FBL www.broad.mit.e...
Broad MORF_HDAC2 View Gene Set 4.737e-18 256 9.632e-17 19 Neighborhood of HDAC2 www.broad.mit.e...
Broad GNF2_ESPL1 View Gene Set 4.618e-18 35 9.632e-17 19 Neighborhood of ESPL1 www.broad.mit.e...
Broad GNF2_MCM4 View Gene Set 4.475e-18 50 9.632e-17 19 Neighborhood of MCM4 www.broad.mit.e...
Broad GNF2_BUB1B View Gene Set 2.05e-17 46 3.978e-16 22 Neighborhood of BUB1B www.broad.mit.e...
Broad MORF_ANP32B View Gene Set 3.651e-17 174 6.778e-16 23 Neighborhood of ANP32B www.broad.mit.e...
Broad GNF2_FEN1 View Gene Set 4.403e-17 49 7.834e-16 24 Neighborhood of FEN1 www.broad.mit.e...
Broad MORF_ACP1 View Gene Set 5.48e-17 178 9.36e-16 25 Neighborhood of ACP1 www.broad.mit.e...
Broad GNF2_CENPE View Gene Set 6.718e-17 37 1.103e-15 26 Neighborhood of CENPE www.broad.mit.e...
Broad MORF_PPP1CC View Gene Set 9.594e-17 150 1.517e-15 27 Neighborhood of PPP1CC www.broad.mit.e...
Broad MORF_CSNK2B View Gene Set 2.07e-16 256 3.157e-15 28 Neighborhood of CSNK2B www.broad.mit.e...
Broad GNF2_RRM2 View Gene Set 2.214e-16 36 3.259e-15 29 Neighborhood of RRM2 www.broad.mit.e...
Broad GNF2_CKS2 View Gene Set 4.938e-16 45 7.028e-15 30 Neighborhood of CKS2 www.broad.mit.e...
Broad MORF_XRCC5 View Gene Set 8.138e-16 210 1.121e-14 31 Neighborhood of XRCC5 www.broad.mit.e...
Broad GNF2_TTK View Gene Set 1.34e-15 34 1.788e-14 32 Neighborhood of TTK www.broad.mit.e...
Broad GNF2_PA2G4 View Gene Set 1.4e-15 73 1.812e-14 33 Neighborhood of PA2G4 www.broad.mit.e...
Broad MORF_SOD1 View Gene Set 1.65e-15 247 2.073e-14 34 Neighborhood of SOD1 www.broad.mit.e...
Broad MORF_HAT1 View Gene Set 3.662e-15 155 4.468e-14 35 Neighborhood of HAT1 www.broad.mit.e...
Broad GNF2_RFC3 View Gene Set 4.287e-15 38 5.085e-14 36 Neighborhood of RFC3 www.broad.mit.e...
Broad GNF2_CKS1B View Gene Set 4.417e-15 36 5.097e-14 37 Neighborhood of CKS1B www.broad.mit.e...
Broad MORF_GNB1 View Gene Set 1.687e-14 276 1.896e-13 38 Neighborhood of GNB1 www.broad.mit.e...
Broad GNF2_RAN View Gene Set 2.754e-14 78 3.015e-13 39 Neighborhood of RAN www.broad.mit.e...
Broad GNF2_APEX1 View Gene Set 4.881e-14 72 5.21e-13 40 Neighborhood of APEX1 www.broad.mit.e...
Broad GNF2_MKI67 View Gene Set 6.048e-14 26 6.299e-13 41 Neighborhood of MKI67 www.broad.mit.e...
Broad MORF_RRM1 View Gene Set 6.726e-14 90 6.839e-13 42 Neighborhood of RRM1 www.broad.mit.e...
Broad GNF2_SMC2L1 View Gene Set 8.617e-14 30 8.557e-13 43 Neighborhood of SMC2L1 www.broad.mit.e...
Broad MORF_RAD54L View Gene Set 9.458e-14 94 9.179e-13 44 Neighborhood of RAD54L www.broad.mit.e...
Broad MORF_BUB1 View Gene Set 1.464e-13 49 1.389e-12 45 Neighborhood of BUB1 www.broad.mit.e...
Broad MORF_RAN View Gene Set 2.104e-13 242 1.953e-12 46 Neighborhood of RAN www.broad.mit.e...
Broad GNF2_BUB1 View Gene Set 2.272e-13 25 2.064e-12 47 Neighborhood of BUB1 www.broad.mit.e...
Broad GNF2_H2AFX View Gene Set 2.865e-13 28 2.548e-12 48 Neighborhood of H2AFX www.broad.mit.e...
Broad MORF_ESPL1 View Gene Set 5.872e-13 58 5.117e-12 49 Neighborhood of ESPL1 www.broad.mit.e...
Broad MORF_AATF View Gene Set 7.531e-13 179 6.431e-12 50 Neighborhood of AATF www.broad.mit.e...
Broad GNF2_DEK View Gene Set 1.746e-12 45 1.462e-11 51 Neighborhood of DEK www.broad.mit.e...
Broad MORF_G22P1 View Gene Set 3.756e-12 145 3.084e-11 52 Neighborhood of G22P1 www.broad.mit.e...
Broad GCM_APEX1 View Gene Set 2.034e-11 102 1.639e-10 53 Neighborhood of APEX1 www.broad.mit.e...
Broad MORF_UNG View Gene Set 4.184e-11 65 3.308e-10 54 Neighborhood of UNG www.broad.mit.e...
Broad GNF2_MCM5 View Gene Set 4.429e-11 51 3.438e-10 55 Neighborhood of MCM5 www.broad.mit.e...
Broad GNF2_XRCC5 View Gene Set 5.461e-11 61 4.164e-10 56 Neighborhood of XRCC5 www.broad.mit.e...
Broad MORF_PCNA View Gene Set 5.628e-11 71 4.216e-10 57 Neighborhood of PCNA www.broad.mit.e...
Broad MORF_PTPN11 View Gene Set 9.88e-11 93 7.274e-10 58 Neighborhood of PTPN11 www.broad.mit.e...
Broad MORF_DEK View Gene Set 2.743e-10 229 1.986e-09 59 Neighborhood of DEK www.broad.mit.e...
Broad MORF_EI24 View Gene Set 3.233e-10 136 2.301e-09 60 Neighborhood of EI24 www.broad.mit.e...
Broad MORF_DEAF1 View Gene Set 3.945e-10 54 2.762e-09 61 Neighborhood of DEAF1 www.broad.mit.e...
Broad MORF_FEN1 View Gene Set 4.422e-10 58 3.046e-09 62 Neighborhood of FEN1 www.broad.mit.e...
Broad MORF_HDAC1 View Gene Set 6.777e-10 222 4.594e-09 63 Neighborhood of HDAC1 www.broad.mit.e...
Broad MORF_RPA2 View Gene Set 8.037e-10 170 5.362e-09 64 Neighborhood of RPA2 www.broad.mit.e...
Broad MORF_DDB1 View Gene Set 1.018e-09 220 6.686e-09 65 Neighborhood of DDB1 www.broad.mit.e...
Broad MORF_UBE2N View Gene Set 1.882e-09 79 1.217e-08 66 Neighborhood of UBE2N www.broad.mit.e...
Broad GNF2_HAT1 View Gene Set 2.209e-09 45 1.408e-08 67 Neighborhood of HAT1 www.broad.mit.e...
Broad MORF_BUB1B View Gene Set 2.777e-09 61 1.744e-08 68 Neighborhood of BUB1B www.broad.mit.e...
Broad GNF2_RBBP6 View Gene Set 3.425e-09 54 2.119e-08 69 Neighborhood of RBBP6 www.broad.mit.e...
Broad MORF_RAD21 View Gene Set 4.133e-09 157 2.521e-08 70 Neighborhood of RAD21 www.broad.mit.e...
Broad GCM_CSNK2B View Gene Set 5.237e-09 88 3.15e-08 71 Neighborhood of CSNK2B www.broad.mit.e...
Broad MORF_CDC16 View Gene Set 1.96e-08 67 1.163e-07 72 Neighborhood of CDC16 www.broad.mit.e...
Broad MORF_GMPS View Gene Set 2.147e-08 48 1.256e-07 73 Neighborhood of GMPS www.broad.mit.e...
Broad MORF_EIF3S6 View Gene Set 2.234e-08 108 1.289e-07 74 Neighborhood of EIF3S6 www.broad.mit.e...
Broad GCM_ACTG1 View Gene Set 2.288e-08 113 1.303e-07 75 Neighborhood of ACTG1 www.broad.mit.e...
Broad MORF_MSH2 View Gene Set 3.031e-08 52 1.681e-07 76 Neighborhood of MSH2 www.broad.mit.e...
Broad MORF_MAP2K2 View Gene Set 2.996e-08 123 1.681e-07 76 Neighborhood of MAP2K2 www.broad.mit.e...
Broad MORF_PRKAG1 View Gene Set 3.898e-08 202 2.134e-07 78 Neighborhood of PRKAG1 www.broad.mit.e...
Broad MORF_DAP3 View Gene Set 3.971e-08 175 2.146e-07 79 Neighborhood of DAP3 www.broad.mit.e...
Broad GNF2_ANP32B View Gene Set 6.566e-08 29 3.505e-07 80 Neighborhood of ANP32B www.broad.mit.e...
Broad MORF_NPM1 View Gene Set 8.979e-08 152 4.733e-07 81 Neighborhood of NPM1 www.broad.mit.e...
Broad GNF2_NPM1 View Gene Set 1.508e-07 57 7.85e-07 82 Neighborhood of NPM1 www.broad.mit.e...
Broad GNF2_KPNB1 View Gene Set 1.533e-07 52 7.889e-07 83 Neighborhood of KPNB1 www.broad.mit.e...
Broad MORF_EIF4A2 View Gene Set 1.726e-07 120 8.773e-07 84 Neighborhood of EIF4A2 www.broad.mit.e...
Broad MORF_SART1 View Gene Set 2.022e-07 55 1.016e-06 85 Neighborhood of SART1 www.broad.mit.e...
Broad GNF2_FBL View Gene Set 2.106e-07 119 1.045e-06 86 Neighborhood of FBL www.broad.mit.e...
Broad GCM_PPP1CC View Gene Set 3.34e-07 47 1.639e-06 87 Neighborhood of PPP1CC www.broad.mit.e...
Broad GNF2_DAP3 View Gene Set 4.062e-07 98 1.971e-06 88 Neighborhood of DAP3 www.broad.mit.e...
Broad GNF2_NS View Gene Set 4.328e-07 35 2.076e-06 89 Neighborhood of NS www.broad.mit.e...
Broad MORF_SNRP70 View Gene Set 4.998e-07 50 2.371e-06 90 Neighborhood of SNRP70 www.broad.mit.e...
Broad GCM_CBFB View Gene Set 5.211e-07 59 2.445e-06 91 Neighborhood of CBFB www.broad.mit.e...
Broad MORF_MTA1 View Gene Set 5.575e-07 95 2.588e-06 92 Neighborhood of MTA1 www.broad.mit.e...
Broad MORF_GSPT1 View Gene Set 1.146e-06 41 5.261e-06 93 Neighborhood of GSPT1 www.broad.mit.e...
Broad GNF2_MSH6 View Gene Set 1.186e-06 30 5.39e-06 94 Neighborhood of MSH6 www.broad.mit.e...
Broad MORF_PHB View Gene Set 1.515e-06 112 6.81e-06 95 Neighborhood of PHB www.broad.mit.e...
Broad MORF_RPA1 View Gene Set 1.572e-06 55 6.992e-06 96 Neighborhood of RPA1 www.broad.mit.e...
Broad MORF_PPP1CA View Gene Set 2.064e-06 145 9.087e-06 97 Neighborhood of PPP1CA www.broad.mit.e...
Broad MORF_CCNI View Gene Set 2.417e-06 76 1.053e-05 98 Neighborhood of CCNI www.broad.mit.e...
Broad GNF2_ST13 View Gene Set 7.337e-06 56 3.165e-05 99 Neighborhood of ST13 www.broad.mit.e...
Broad GNF2_HDAC1 View Gene Set 7.686e-06 85 3.282e-05 100 Neighborhood of HDAC1 www.broad.mit.e...
Broad MORF_CDK2 View Gene Set 1.071e-05 63 4.527e-05 101 Neighborhood of CDK2 www.broad.mit.e...
Broad MORF_ERH View Gene Set 1.163e-05 103 4.868e-05 102 Neighborhood of ERH www.broad.mit.e...
Broad GNF2_MSH2 View Gene Set 1.238e-05 26 5.133e-05 103 Neighborhood of MSH2 www.broad.mit.e...
Broad MORF_SMC1L1 View Gene Set 1.692e-05 47 6.879e-05 104 Neighborhood of SMC1L1 www.broad.mit.e...
Broad GNF2_SMC1L1 View Gene Set 1.677e-05 24 6.879e-05 104 Neighborhood of SMC1L1 www.broad.mit.e...
Broad MORF_SKP1A View Gene Set 2.161e-05 175 8.705e-05 106 Neighborhood of SKP1A www.broad.mit.e...
Broad GCM_NPM1 View Gene Set 2.732e-05 108 0.000109 107 Neighborhood of NPM1 www.broad.mit.e...
Broad MORF_CDC10 View Gene Set 2.985e-05 120 0.000118 108 Neighborhood of CDC10 www.broad.mit.e...
Broad GCM_PSME1 View Gene Set 3.375e-05 76 0.0001322 109 Neighborhood of PSME1 www.broad.mit.e...
Broad GNF2_RPA1 View Gene Set 3.642e-05 20 0.0001414 110 Neighborhood of RPA1 www.broad.mit.e...
Broad GNF2_G22P1 View Gene Set 3.86e-05 29 0.0001485 111 Neighborhood of G22P1 www.broad.mit.e...
Broad MORF_CTBP1 View Gene Set 3.945e-05 149 0.0001491 112 Neighborhood of CTBP1 www.broad.mit.e...
Broad MORF_NME2 View Gene Set 3.91e-05 145 0.0001491 112 Neighborhood of NME2 www.broad.mit.e...
Broad MORF_PSMC1 View Gene Set 4.16e-05 162 0.0001558 114 Neighborhood of PSMC1 www.broad.mit.e...
Broad GNF2_MLH1 View Gene Set 4.406e-05 36 0.0001636 115 Neighborhood of MLH1 www.broad.mit.e...
Broad MORF_TERF1 View Gene Set 4.982e-05 57 0.0001834 116 Neighborhood of TERF1 www.broad.mit.e...
Broad MORF_USP5 View Gene Set 7.552e-05 46 0.0002756 117 Neighborhood of USP5 www.broad.mit.e...
Broad MORF_CCNF View Gene Set 0.0001064 65 0.0003849 118 Neighborhood of CCNF www.broad.mit.e...
Broad GNF2_EIF3S6 View Gene Set 0.0001287 109 0.0004616 119 Neighborhood of EIF3S6 www.broad.mit.e...
Broad GCM_DFFA View Gene Set 0.0001438 100 0.0005118 120 Neighborhood of DFFA www.broad.mit.e...
Broad GNF2_UBE2I View Gene Set 0.0001537 33 0.0005425 121 Neighborhood of UBE2I www.broad.mit.e...
Broad GNF2_DENR View Gene Set 0.0001866 39 0.000653 122 Neighborhood of DENR www.broad.mit.e...
Broad GNF2_BUB3 View Gene Set 0.0001947 22 0.0006758 123 Neighborhood of BUB3 www.broad.mit.e...
Broad MORF_FANCG View Gene Set 0.0002945 148 0.001014 124 Neighborhood of FANCG www.broad.mit.e...
Broad MORF_CUL1 View Gene Set 0.0003108 62 0.001062 125 Neighborhood of CUL1 www.broad.mit.e...
Broad MORF_PPP2R5E View Gene Set 0.0003188 76 0.00108 126 Neighborhood of PPP2R5E www.broad.mit.e...
Broad GNF2_ELAC2 View Gene Set 0.0004107 32 0.001381 127 Neighborhood of ELAC2 www.broad.mit.e...
Broad GNF2_TDG View Gene Set 0.0006761 23 0.002256 128 Neighborhood of TDG www.broad.mit.e...
Broad MORF_TPR View Gene Set 0.0007637 131 0.002528 129 Neighborhood of TPR www.broad.mit.e...
Broad MORF_RAB11A View Gene Set 0.0007795 53 0.00256 130 Neighborhood of RAB11A www.broad.mit.e...
Broad GCM_NF2 View Gene Set 0.0009597 235 0.003128 131 Neighborhood of NF2 www.broad.mit.e...
Broad GCM_DDX5 View Gene Set 0.001024 52 0.003312 132 Neighborhood of DDX5 www.broad.mit.e...
Broad GCM_AIP View Gene Set 0.0017 36 0.005458 133 Neighborhood of AIP www.broad.mit.e...
Broad MORF_ACTG1 View Gene Set 0.001804 134 0.00575 134 Neighborhood of ACTG1 www.broad.mit.e...
Broad GCM_MYST2 View Gene Set 0.002096 138 0.006628 135 Neighborhood of MYST2 www.broad.mit.e...
Broad MORF_RFC1 View Gene Set 0.002122 98 0.006663 136 Neighborhood of RFC1 www.broad.mit.e...
Broad MORF_EIF4E View Gene Set 0.002766 76 0.008623 137 Neighborhood of EIF4E www.broad.mit.e...
Broad MORF_RAF1 View Gene Set 0.003512 94 0.01087 138 Neighborhood of RAF1 www.broad.mit.e...
Broad MORF_BMI1 View Gene Set 0.003821 71 0.01174 139 Neighborhood of BMI1 www.broad.mit.e...
Broad MORF_SS18 View Gene Set 0.004589 55 0.014 140 Neighborhood of SS18 www.broad.mit.e...
Broad GCM_TPR View Gene Set 0.004688 29 0.0142 141 Neighborhood of TPR www.broad.mit.e...
Broad MORF_RAD23B View Gene Set 0.004958 159 0.01491 142 Neighborhood of RAD23B www.broad.mit.e...
Broad MORF_REV3L View Gene Set 0.005052 52 0.01509 143 Neighborhood of REV3L www.broad.mit.e...
Broad GCM_BECN1 View Gene Set 0.005536 59 0.01642 144 Neighborhood of BECN1 www.broad.mit.e...
Broad GCM_RBM8A View Gene Set 0.005934 64 0.01747 145 Neighborhood of RBM8A www.broad.mit.e...
Broad GCM_GSPT1 View Gene Set 0.00602 129 0.01761 146 Neighborhood of GSPT1 www.broad.mit.e...
Broad MORF_AP2M1 View Gene Set 0.007387 197 0.02146 147 Neighborhood of AP2M1 www.broad.mit.e...
Broad GCM_VAV1 View Gene Set 0.009134 46 0.02635 148 Neighborhood of VAV1 www.broad.mit.e...
Broad GCM_PFN1 View Gene Set 0.00992 47 0.02843 149 Neighborhood of PFN1 www.broad.mit.e...
Broad GCM_SMO View Gene Set 0.01009 49 0.02871 150 Neighborhood of SMO www.broad.mit.e...
Broad GCM_DENR View Gene Set 0.01116 40 0.03157 151 Neighborhood of DENR www.broad.mit.e...
Broad GCM_ING1 View Gene Set 0.01309 50 0.03678 152 Neighborhood of ING1 www.broad.mit.e...
Broad MORF_ORC1L View Gene Set 0.01372 61 0.03828 153 Neighborhood of ORC1L www.broad.mit.e...
Broad MORF_AP3D1 View Gene Set 0.01403 119 0.03892 154 Neighborhood of AP3D1 www.broad.mit.e...
Broad MORF_BECN1 View Gene Set 0.016 93 0.04408 155 Neighborhood of BECN1 www.broad.mit.e...
Broad GCM_RAD21 View Gene Set 0.01666 30 0.04531 156 Neighborhood of RAD21 www.broad.mit.e...
Broad GNF2_PPP6C View Gene Set 0.01661 33 0.04531 156 Neighborhood of PPP6C www.broad.mit.e...
Broad MORF_PPP2CA View Gene Set 0.01697 110 0.04586 158 Neighborhood of PPP2CA www.broad.mit.e...
Broad MORF_IKBKG View Gene Set 0.01775 119 0.04768 159 Neighborhood of IKBKG www.broad.mit.e...

Gene Set Collection: Broad.c4.CM

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad module_54 View Gene Set 1.749e-33 242 7.94e-31 1 Genes in module_54 www.broad.mit.e...
Broad module_17 View Gene Set 2.361e-15 351 5.359e-13 2 Genes in module_17 www.broad.mit.e...
Broad module_198 View Gene Set 1.173e-14 288 1.775e-12 3 Genes in module_198 www.broad.mit.e...
Broad module_98 View Gene Set 1.17e-13 375 1.181e-11 4 Genes in module_98 www.broad.mit.e...
Broad module_252 View Gene Set 1.3e-13 224 1.181e-11 4 Genes in module_252 www.broad.mit.e...
Broad module_244 View Gene Set 1.039e-12 182 7.861e-11 6 Genes in module_244 www.broad.mit.e...
Broad module_403 View Gene Set 1.116e-09 44 7.237e-08 7 Genes in module_403 www.broad.mit.e...
Broad module_32 View Gene Set 2.114e-09 227 1.2e-07 8 Genes in module_32 www.broad.mit.e...
Broad module_124 View Gene Set 2.749e-09 92 1.387e-07 9 Genes in module_124 www.broad.mit.e...
Broad module_397 View Gene Set 2.961e-08 114 1.345e-06 10 Genes in module_397 www.broad.mit.e...
Broad module_320 View Gene Set 5.15e-08 19 2.126e-06 11 Genes in module_320 www.broad.mit.e...
Broad module_126 View Gene Set 7.224e-08 173 2.733e-06 12 Genes in module_126 www.broad.mit.e...
Broad module_219 View Gene Set 1.259e-07 26 4.396e-06 13 Genes in module_219 www.broad.mit.e...
Broad module_158 View Gene Set 2.207e-07 41 6.681e-06 14 Genes in module_158 www.broad.mit.e...
Broad module_183 View Gene Set 2.11e-07 52 6.681e-06 14 Genes in module_183 www.broad.mit.e...
Broad module_125 View Gene Set 3.138e-07 42 8.905e-06 16 Genes in module_125 www.broad.mit.e...
Broad module_315 View Gene Set 3.794e-07 15 1.013e-05 17 Genes in module_315 www.broad.mit.e...
Broad module_337 View Gene Set 4.222e-07 59 1.065e-05 18 Genes in module_337 www.broad.mit.e...
Broad module_392 View Gene Set 8.056e-07 18 1.925e-05 19 Genes in module_392 www.broad.mit.e...
Broad module_28 View Gene Set 2.444e-06 32 5.548e-05 20 Genes in module_28 www.broad.mit.e...
Broad module_91 View Gene Set 4.266e-06 37 9.223e-05 21 Genes in module_91 www.broad.mit.e...
Broad module_197 View Gene Set 5.1e-06 170 0.0001053 22 Genes in module_197 www.broad.mit.e...
Broad module_57 View Gene Set 5.709e-06 54 0.000108 23 Genes in module_57 www.broad.mit.e...
Broad module_451 View Gene Set 5.571e-06 29 0.000108 23 Genes in module_451 www.broad.mit.e...
Broad module_35 View Gene Set 4.691e-05 16 0.0008518 25 Genes in module_35 www.broad.mit.e...
Broad module_110 View Gene Set 5.659e-05 15 0.0009881 26 Genes in module_110 www.broad.mit.e...
Broad module_388 View Gene Set 8.037e-05 17 0.001351 27 Genes in module_388 www.broad.mit.e...
Broad module_133 View Gene Set 8.874e-05 15 0.001439 28 Genes in module_133 www.broad.mit.e...
Broad module_160 View Gene Set 0.0001077 15 0.001687 29 Genes in module_160 www.broad.mit.e...
Broad module_61 View Gene Set 0.000148 50 0.002239 30 Genes in module_61 www.broad.mit.e...
Broad module_352 View Gene Set 0.0001652 17 0.00242 31 Genes in module_352 www.broad.mit.e...
Broad module_83 View Gene Set 0.0004431 296 0.006287 32 Genes in module_83 www.broad.mit.e...
Broad module_102 View Gene Set 0.0004993 18 0.006869 33 Genes in module_102 www.broad.mit.e...
Broad module_253 View Gene Set 0.0008645 21 0.01096 34 Genes in module_253 www.broad.mit.e...
Broad module_273 View Gene Set 0.0008668 50 0.01096 34 Genes in module_273 www.broad.mit.e...
Broad module_278 View Gene Set 0.0008688 34 0.01096 34 Genes in module_278 www.broad.mit.e...
Broad module_457 View Gene Set 0.0008978 9 0.01102 37 Genes in module_457 www.broad.mit.e...
Broad module_363 View Gene Set 0.001048 48 0.01252 38 Genes in module_363 www.broad.mit.e...
Broad module_21 View Gene Set 0.001246 10 0.0145 39 Genes in module_21 www.broad.mit.e...
Broad module_421 View Gene Set 0.001325 23 0.01504 40 Genes in module_421 www.broad.mit.e...
Broad module_152 View Gene Set 0.001526 121 0.01689 41 Genes in module_152 www.broad.mit.e...
Broad module_105 View Gene Set 0.001787 192 0.01932 42 Genes in module_105 www.broad.mit.e...
Broad module_50 View Gene Set 0.001958 13 0.02067 43 Genes in module_50 www.broad.mit.e...
Broad module_127 View Gene Set 0.002055 26 0.0212 44 Genes in module_127 www.broad.mit.e...
Broad module_3 View Gene Set 0.002288 374 0.02307 45 Genes in module_3 www.broad.mit.e...
Broad module_168 View Gene Set 0.002358 22 0.02307 45 Genes in module_168 www.broad.mit.e...
Broad module_485 View Gene Set 0.002388 44 0.02307 45 Genes in module_485 www.broad.mit.e...
Broad module_222 View Gene Set 0.002722 22 0.02574 48 Genes in module_222 www.broad.mit.e...
Broad module_203 View Gene Set 0.003133 16 0.02903 49 Genes in module_203 www.broad.mit.e...
Broad module_196 View Gene Set 0.003497 23 0.03175 50 Genes in module_196 www.broad.mit.e...
Broad module_299 View Gene Set 0.00378 33 0.03365 51 Genes in module_299 www.broad.mit.e...
Broad module_90 View Gene Set 0.004066 17 0.0355 52 Genes in module_90 www.broad.mit.e...
Broad module_155 View Gene Set 0.004519 25 0.03871 53 Genes in module_155 www.broad.mit.e...
Broad module_331 View Gene Set 0.004962 65 0.04172 54 Genes in module_331 www.broad.mit.e...
Broad module_72 View Gene Set 0.005445 293 0.04494 55 Genes in module_72 www.broad.mit.e...
Broad module_207 View Gene Set 0.005995 195 0.0486 56 Genes in module_207 www.broad.mit.e...

Gene Set Collection: Broad.c5.BP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad CELL_CYCLE_PROCESS View Gene Set 4.902e-13 187 4.044e-10 1 Genes annotated by the GO term GO:0022402. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. www.broad.mit.e...
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 2.021e-12 1197 4.201e-10 2 Genes annotated by the GO term GO:0006139. The chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad MITOSIS View Gene Set 2.037e-12 81 4.201e-10 2 Genes annotated by the GO term GO:0007067. Progression through mitosis the division of the eukaryotic cell nucleus to produce two daughter nuclei that usually contain the identical chromosome complement to their mother. www.broad.mit.e...
Broad M_PHASE_OF_MITOTIC_CELL_CYCLE View Gene Set 1.875e-12 83 4.201e-10 2 Genes annotated by the GO term GO:0000087. Progression through M phase the part of the mitotic cell cycle during which mitosis takes place. www.broad.mit.e...
Broad M_PHASE View Gene Set 6.993e-12 111 1.154e-09 5 Genes annotated by the GO term GO:0000279. Progression through M phase the part of the cell cycle comprising nuclear division. www.broad.mit.e...
Broad RNA_PROCESSING View Gene Set 1.377e-11 147 1.894e-09 6 Genes annotated by the GO term GO:0006396. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. www.broad.mit.e...
Broad MITOTIC_CELL_CYCLE View Gene Set 2.957e-10 148 3.485e-08 7 Genes annotated by the GO term GO:0000278. Progression through the phases of the mitotic cell cycle the most common eukaryotic cell cycle which canonically comprises four successive phases called G1 S G2 and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division or G1 and G2 phases may be absent. www.broad.mit.e...
Broad CELL_CYCLE_PHASE View Gene Set 1.79e-09 167 1.846e-07 8 Genes annotated by the GO term GO:0022403. A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. www.broad.mit.e...
Broad CELL_CYCLE_GO_0007049 View Gene Set 2.873e-09 304 2.634e-07 9 Genes annotated by the GO term GO:0007049. The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. www.broad.mit.e...
Broad RNA_SPLICING View Gene Set 4.348e-08 73 3.587e-06 10 Genes annotated by the GO term GO:0008380. The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. www.broad.mit.e...
Broad DNA_METABOLIC_PROCESS View Gene Set 5.139e-08 253 3.854e-06 11 Genes annotated by the GO term GO:0006259. The chemical reactions and pathways involving DNA deoxyribonucleic acid one of the two main types of nucleic acid consisting of a long unbranched macromolecule formed from one or more commonly two strands of linked deoxyribonucleotides. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY View Gene Set 1.354e-07 74 9.307e-06 12 Genes annotated by the GO term GO:0022613. The cellular process by which a complex containing RNA and proteins is synthesized aggregates and bonds together. www.broad.mit.e...
Broad DNA_REPAIR View Gene Set 8.284e-07 123 5.257e-05 13 Genes annotated by the GO term GO:0006281. The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations chemical mutagens fungal and bacterial toxins etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal base excision repair nucleotide excision repair photoreactivation bypass double-strand break repair pathway and mismatch repair pathway. www.broad.mit.e...
Broad RNA_METABOLIC_PROCESS View Gene Set 1.679e-06 801 9.892e-05 14 Genes annotated by the GO term GO:0016070. The chemical reactions and pathways involving RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. www.broad.mit.e...
Broad BIOPOLYMER_METABOLIC_PROCESS View Gene Set 1.847e-06 1623 0.0001016 15 Genes annotated by the GO term GO:0043283. The chemical reactions and pathways involving biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. www.broad.mit.e...
Broad MRNA_PROCESSING_GO_0006397 View Gene Set 3.483e-06 59 0.0001796 16 Genes annotated by the GO term GO:0006397. Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. www.broad.mit.e...
Broad RESPONSE_TO_DNA_DAMAGE_STIMULUS View Gene Set 5.945e-06 159 0.0002885 17 Genes annotated by the GO term GO:0006974. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. www.broad.mit.e...
Broad TRANSLATION View Gene Set 6.554e-06 177 0.0003004 18 Genes annotated by the GO term GO:0006412. The chemical reactions and pathways resulting in the formation of a protein. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. www.broad.mit.e...
Broad CHROMOSOME_ORGANIZATION_AND_BIOGENESIS View Gene Set 8.112e-06 117 0.0003523 19 Genes annotated by the GO term GO:0051276. A process that is carried out at the cellular level that results in the formation arrangement of constituent parts or disassembly of chromosomes structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. www.broad.mit.e...
Broad PROTEIN_RNA_COMPLEX_ASSEMBLY View Gene Set 1.239e-05 59 0.0004992 20 Genes annotated by the GO term GO:0022618. The aggregation arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. www.broad.mit.e...
Broad MRNA_METABOLIC_PROCESS View Gene Set 1.271e-05 70 0.0004992 20 Genes annotated by the GO term GO:0016071. The chemical reactions and pathways involving mRNA messenger RNA which is responsible for carrying the coded genetic 'message' transcribed from DNA to sites of protein assembly at the ribosomes. www.broad.mit.e...
Broad RESPONSE_TO_ENDOGENOUS_STIMULUS View Gene Set 1.675e-05 197 0.000628 22 Genes annotated by the GO term GO:0009719. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of an endogenous stimulus. www.broad.mit.e...
Broad CELLULAR_BIOSYNTHETIC_PROCESS View Gene Set 2.063e-05 311 0.000725 23 Genes annotated by the GO term GO:0044249. The chemical reactions and pathways resulting in the formation of substances carried out by individual cells. www.broad.mit.e...
Broad CELL_CYCLE_CHECKPOINT_GO_0000075 View Gene Set 2.109e-05 47 0.000725 23 Genes annotated by the GO term GO:0000075. A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. www.broad.mit.e...
Broad REGULATION_OF_MITOSIS View Gene Set 5.497e-05 40 0.001814 25 Genes annotated by the GO term GO:0007088. Any process that modulates the frequency rate or extent of mitosis. www.broad.mit.e...
Broad RIBOSOME_BIOGENESIS_AND_ASSEMBLY View Gene Set 5.757e-05 14 0.001827 26 Genes annotated by the GO term GO:0042254. The process of the formation of the constituents of the ribosome subunits their assembly and their transport to the sites of protein synthesis. www.broad.mit.e...
Broad RRNA_METABOLIC_PROCESS View Gene Set 8.859e-05 12 0.002707 27 Genes annotated by the GO term GO:0016072. The chemical reactions and pathways involving rRNA ribosomal RNA a structural constituent of ribosomes. www.broad.mit.e...
Broad ORGANELLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 9.822e-05 458 0.002848 28 Genes annotated by the GO term GO:0006996. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of any organelle within a cell. www.broad.mit.e...
Broad RRNA_PROCESSING View Gene Set 0.0001001 11 0.002848 28 Genes annotated by the GO term GO:0006364. Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. www.broad.mit.e...
Broad MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0001375 34 0.003781 30 Genes annotated by the GO term GO:0000226. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. www.broad.mit.e...
Broad MITOTIC_SISTER_CHROMATID_SEGREGATION View Gene Set 0.0001595 16 0.004245 31 Genes annotated by the GO term GO:0000070. The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome composed of two sister chromatids aligns at the cell equator paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. www.broad.mit.e...
Broad MITOTIC_CELL_CYCLE_CHECKPOINT View Gene Set 0.0001907 21 0.004916 32 Genes annotated by the GO term GO:0007093. A signal transduction-based surveillance mechanism that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage. www.broad.mit.e...
Broad RNA_SPLICINGVIA_TRANSESTERIFICATION_REACTIONS View Gene Set 0.0002279 27 0.005697 33 Genes annotated by the GO term GO:0000375. Splicing of RNA via a series of two transesterification reactions. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX_ASSEMBLY View Gene Set 0.0002691 271 0.006529 34 Genes annotated by the GO term GO:0065003. The aggregation arrangement and bonding together of a set of macromolecules to form a complex. www.broad.mit.e...
Broad PROTEIN_FOLDING View Gene Set 0.0003567 56 0.008409 35 Genes annotated by the GO term GO:0006457. The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. www.broad.mit.e...
Broad MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0003932 16 0.00901 36 Genes annotated by the GO term GO:0031023. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a microtubule organizing center a structure from which microtubules grow. www.broad.mit.e...
Broad PROTEIN_CATABOLIC_PROCESS View Gene Set 0.0004293 68 0.009418 37 Genes annotated by the GO term GO:0030163. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native active configuration with or without the hydrolysis of peptide bonds. www.broad.mit.e...
Broad BASE_EXCISION_REPAIR View Gene Set 0.0004338 16 0.009418 37 Genes annotated by the GO term GO:0006284. In base excision repair an altered base is removed by a DNA glycosylase enzyme followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. www.broad.mit.e...
Broad COENZYME_METABOLIC_PROCESS View Gene Set 0.0004482 37 0.009481 39 Genes annotated by the GO term GO:0006732. The chemical reactions and pathways involving coenzymes any of various nonprotein organic cofactors that are required in addition to an enzyme and a substrate for an enzymatic reaction to proceed. www.broad.mit.e...
Broad SPINDLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0004745 10 0.009786 40 Genes annotated by the GO term GO:0007051. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the spindle the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. www.broad.mit.e...
Broad COFACTOR_METABOLIC_PROCESS View Gene Set 0.0005421 53 0.01065 41 Genes annotated by the GO term GO:0051186. The chemical reactions and pathways involving a cofactor a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic such as the metal atoms zinc iron and copper in certain forms or organic in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. www.broad.mit.e...
Broad SISTER_CHROMATID_SEGREGATION View Gene Set 0.0005405 17 0.01065 41 Genes annotated by the GO term GO:0000819. The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets. www.broad.mit.e...
Broad CHROMOSOME_CONDENSATION View Gene Set 0.0005841 10 0.01121 43 Genes annotated by the GO term GO:0030261. The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division or during apoptosis in eukaryotic cells. www.broad.mit.e...
Broad MITOCHONDRION_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0006019 47 0.01129 44 Genes annotated by the GO term GO:0007005. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a mitochondrion; includes mitochondrial morphology and distribution and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. www.broad.mit.e...
Broad CELLULAR_PROTEIN_CATABOLIC_PROCESS View Gene Set 0.000664 58 0.01217 45 Genes annotated by the GO term GO:0044257. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. www.broad.mit.e...
Broad DNA_RECOMBINATION View Gene Set 0.0007146 47 0.01282 46 Genes annotated by the GO term GO:0006310. The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment intrachromosomal recombination or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation conjugation transduction or F-duction. www.broad.mit.e...
Broad CELLULAR_COMPONENT_ASSEMBLY View Gene Set 0.000765 288 0.01343 47 Genes annotated by the GO term GO:0022607. A cellular process that results in the assembly of a part of the cell. www.broad.mit.e...
Broad TRANSLATIONAL_INITIATION View Gene Set 0.0009461 39 0.01593 48 Genes annotated by the GO term GO:0006413. The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome mRNA and an initiation complex that contains the first aminoacyl-tRNA. www.broad.mit.e...
Broad MITOTIC_SPINDLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0009405 9 0.01593 48 Genes annotated by the GO term GO:0007052. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the microtubule spindle during a mitotic cell cycle. www.broad.mit.e...
Broad BIOPOLYMER_CATABOLIC_PROCESS View Gene Set 0.001104 115 0.01821 50 Genes annotated by the GO term GO:0043285. The chemical reactions and pathways resulting in the breakdown of biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. www.broad.mit.e...
Broad MITOCHONDRIAL_TRANSPORT View Gene Set 0.001162 20 0.01879 51 Genes annotated by the GO term GO:0006839. Transport of substances into out of or within a mitochondrion. www.broad.mit.e...
Broad TRNA_METABOLIC_PROCESS View Gene Set 0.001197 18 0.01899 52 Genes annotated by the GO term GO:0006399. The chemical reactions and pathways involving tRNA transfer RNA a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases the function of which has not been completely established. www.broad.mit.e...
Broad CENTROSOME_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.001271 15 0.01978 53 Genes annotated by the GO term GO:0051297. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a centrosome a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. www.broad.mit.e...
Broad DNA_REPLICATION_INITIATION View Gene Set 0.001431 15 0.02109 54 Genes annotated by the GO term GO:0006270. The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix the recruitment of DNA polymerases and the initiation of polymerase action. www.broad.mit.e...
Broad DNA_REPLICATION View Gene Set 0.001427 101 0.02109 54 Genes annotated by the GO term GO:0006260. The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. www.broad.mit.e...
Broad CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS View Gene Set 0.001392 103 0.02109 54 Genes annotated by the GO term GO:0044265. The chemical reactions and pathways resulting in the breakdown of a macromolecule any large molecule including proteins nucleic acids and carbohydrates as carried out by individual cells. www.broad.mit.e...
Broad DNA_INTEGRITY_CHECKPOINT View Gene Set 0.001724 23 0.02373 57 Genes annotated by the GO term GO:0031570. Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure. www.broad.mit.e...
Broad RESPONSE_TO_CARBOHYDRATE_STIMULUS View Gene Set 0.001655 12 0.02373 57 Genes annotated by the GO term GO:0009743. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a carbohydrate stimulus. www.broad.mit.e...
Broad CHROMOSOME_SEGREGATION View Gene Set 0.001726 31 0.02373 57 Genes annotated by the GO term GO:0007059. The process by which genetic material in the form of chromosomes is organized and then physically separated and apportioned to two or more sets. www.broad.mit.e...
Broad MACROMOLECULE_CATABOLIC_PROCESS View Gene Set 0.001724 135 0.02373 57 Genes annotated by the GO term GO:0009057. The chemical reactions and pathways resulting in the breakdown of a macromolecule any large molecule including proteins nucleic acids and carbohydrates. www.broad.mit.e...
Broad CELLULAR_PROTEIN_COMPLEX_ASSEMBLY View Gene Set 0.00179 33 0.02422 61 Genes annotated by the GO term GO:0043623. The aggregation arrangement and bonding together of a set of components to form a protein complex occurring at the level of an individual cell. www.broad.mit.e...
Broad DNA_DEPENDENT_DNA_REPLICATION View Gene Set 0.001945 55 0.02588 62 Genes annotated by the GO term GO:0006261. The process whereby new strands of DNA are synthesized using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. www.broad.mit.e...
Broad AMINO_ACID_METABOLIC_PROCESS View Gene Set 0.002198 75 0.02878 63 Genes annotated by the GO term GO:0006520. The chemical reactions and pathways involving amino acids organic acids containing one or more amino substituents. www.broad.mit.e...
Broad CELLULAR_RESPIRATION View Gene Set 0.002449 19 0.03157 64 Genes annotated by the GO term GO:0045333. The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration). www.broad.mit.e...

Gene Set Collection: Broad.c5.CC

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad NUCLEAR_PART View Gene Set 3.31e-22 543 3.856e-20 1 Genes annotated by the GO term GO:0044428. Any constituent part of the nucleus a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. www.broad.mit.e...
Broad NUCLEUS View Gene Set 2.769e-22 1353 3.856e-20 1 Genes annotated by the GO term GO:0005634. A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells the nucleus contains all of the cell's chromosomes except the organellar chromosomes and is the site of RNA synthesis and processing. In some species or in specialized cell types RNA metabolism or DNA replication may be absent. www.broad.mit.e...
Broad INTRACELLULAR_ORGANELLE_PART View Gene Set 7.783e-19 1144 6.045e-17 3 Genes annotated by the GO term GO:0044446. A constituent part of an intracellular organelle an organized structure of distinctive morphology and function occurring within the cell. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad ORGANELLE_PART View Gene Set 1.475e-18 1149 8.594e-17 4 Genes annotated by the GO term GO:0044422. Any constituent part of an organelle an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad ORGANELLE_LUMEN View Gene Set 1.172e-13 434 4.549e-12 5 Genes annotated by the GO term GO:0043233. The volume enclosed by the membranes of a particular organelle e.g. endoplasmic reticulum lumen or the space between the two lipid bilayers of a double membrane surrounding an organelle e.g. nuclear membrane lumen. www.broad.mit.e...
Broad MEMBRANE_ENCLOSED_LUMEN View Gene Set 1.172e-13 434 4.549e-12 5 Genes annotated by the GO term GO:0031974. The enclosed volume within a sealed membrane or between two sealed membranes. www.broad.mit.e...
Broad MITOCHONDRION View Gene Set 2.893e-13 335 9.629e-12 7 Genes annotated by the GO term GO:0005739. A semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. www.broad.mit.e...
Broad NUCLEAR_LUMEN View Gene Set 6.315e-12 365 1.839e-10 8 Genes annotated by the GO term GO:0031981. The volume enclosed by the nuclear inner membrane. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX View Gene Set 5.58e-10 914 1.444e-08 9 Genes annotated by the GO term GO:0032991. A stable assembly of two or more macromolecules i.e. proteins nucleic acids carbohydrates or lipids in which the constituent parts function together. www.broad.mit.e...
Broad MITOCHONDRIAL_PART View Gene Set 2.799e-09 140 5.747e-08 10 Genes annotated by the GO term GO:0044429. Any constituent part of a mitochondrion a semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX View Gene Set 3.207e-09 129 5.747e-08 10 Genes annotated by the GO term GO:0030529. A macromolecular complex containing both protein and RNA molecules. www.broad.mit.e...
Broad ENVELOPE View Gene Set 3.039e-09 165 5.747e-08 10 Genes annotated by the GO term GO:0031975. A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers and may include a cell wall layer also includes the space between layers. www.broad.mit.e...
Broad ORGANELLE_ENVELOPE View Gene Set 3.039e-09 165 5.747e-08 10 Genes annotated by the GO term GO:0031967. A double membrane structure enclosing an organelle including two lipid bilayers and the region between them. In some cases an organelle envelope may have more than two membranes. www.broad.mit.e...
Broad NON_MEMBRANE_BOUND_ORGANELLE View Gene Set 5.098e-09 613 7.919e-08 14 Genes annotated by the GO term GO:0043228. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane. Includes ribosomes the cytoskeleton and chromosomes. www.broad.mit.e...
Broad INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE View Gene Set 5.098e-09 613 7.919e-08 14 Genes annotated by the GO term GO:0043232. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes the cytoskeleton and chromosomes. www.broad.mit.e...
Broad SPLICEOSOME View Gene Set 7.775e-09 44 1.132e-07 16 Genes annotated by the GO term GO:0005681. A ribonucleoprotein complex containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron. www.broad.mit.e...
Broad CHROMOSOME View Gene Set 1.252e-08 122 1.716e-07 17 Genes annotated by the GO term GO:0005694. A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. www.broad.mit.e...
Broad MICROTUBULE_CYTOSKELETON View Gene Set 3.262e-08 146 4.223e-07 18 Genes annotated by the GO term GO:0015630. The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. www.broad.mit.e...
Broad NUCLEOPLASM View Gene Set 3.581e-08 266 4.392e-07 19 Genes annotated by the GO term GO:0005654. That part of the nuclear content other than the chromosomes or the nucleolus. www.broad.mit.e...
Broad CHROMOSOMAL_PART View Gene Set 9.027e-08 95 1.052e-06 20 Genes annotated by the GO term GO:0044427. Any constituent part of a chromosome a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. www.broad.mit.e...
Broad MICROTUBULE_ORGANIZING_CENTER View Gene Set 1.541e-07 64 1.709e-06 21 Genes annotated by the GO term GO:0005815. A region in a eukaryotic cell such as a centrosome or basal body from which microtubules grow. www.broad.mit.e...
Broad MITOCHONDRIAL_MEMBRANE View Gene Set 1.923e-07 85 2.036e-06 22 Genes annotated by the GO term GO:0031966. Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. www.broad.mit.e...
Broad MITOCHONDRIAL_ENVELOPE View Gene Set 5.138e-07 95 5.205e-06 23 Genes annotated by the GO term GO:0005740. The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space. www.broad.mit.e...
Broad CENTROSOME View Gene Set 1.769e-06 55 1.718e-05 24 Genes annotated by the GO term GO:0005813. A structure comprised of a core structure (in most organisms a pair of centrioles) and peripheral material from which a microtubule-based structure such as a spindle apparatus is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells though in animal cells it changes continually during the cell-division cycle. www.broad.mit.e...
Broad MITOCHONDRIAL_MEMBRANE_PART View Gene Set 2.638e-06 52 2.459e-05 25 Genes annotated by the GO term GO:0044455. Any constituent part of the mitochondrial membrane either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. www.broad.mit.e...
Broad PROTEIN_COMPLEX View Gene Set 4.126e-06 799 3.698e-05 26 Genes annotated by the GO term GO:0043234. Any protein group composed of two or more subunits which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. www.broad.mit.e...
Broad CHROMOSOMEPERICENTRIC_REGION View Gene Set 7.926e-06 31 6.84e-05 27 Genes annotated by the GO term GO:0000775. The central region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes this region corresponds to a single area of the chromosome whereas in holocentric chromosomes it is evenly distributed along the chromosome. www.broad.mit.e...
Broad MITOCHONDRIAL_INNER_MEMBRANE View Gene Set 8.973e-06 66 7.467e-05 28 Genes annotated by the GO term GO:0005743. The inner i.e. lumen-facing lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. www.broad.mit.e...
Broad NUCLEOLUS View Gene Set 1.024e-05 116 8.23e-05 29 Genes annotated by the GO term GO:0005730. A small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA the processing of this RNA into 5.8S 18S and 28S components of ribosomal RNA and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. www.broad.mit.e...
Broad ORGANELLE_INNER_MEMBRANE View Gene Set 1.378e-05 74 0.000107 30 Genes annotated by the GO term GO:0019866. The inner i.e. lumen-facing lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites. www.broad.mit.e...
Broad SPINDLE View Gene Set 1.506e-05 37 0.0001132 31 Genes annotated by the GO term GO:0005819. The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. www.broad.mit.e...
Broad SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX View Gene Set 1.705e-05 20 0.0001242 32 Genes annotated by the GO term GO:0030532. A complex composed of RNA of the small nuclear RNA (snRNA) class and protein found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain e.g. U1 snRNP or U4/U6 snRNP. Many but not all of these complexes are involved in splicing of nuclear mRNAs. www.broad.mit.e...
Broad NUCLEOPLASM_PART View Gene Set 2.89e-05 202 0.0002041 33 Genes annotated by the GO term GO:0044451. Any constituent part of the nucleoplasm that part of the nuclear content other than the chromosomes or the nucleolus. www.broad.mit.e...
Broad CONDENSED_CHROMOSOME View Gene Set 4.159e-05 32 0.000285 34 Genes annotated by the GO term GO:0000793. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. www.broad.mit.e...
Broad CYTOSKELETAL_PART View Gene Set 7.721e-05 231 0.0004988 35 Genes annotated by the GO term GO:0044430. Any constituent part of the cytoskeleton a cellular scaffolding or skeleton that maintains cell shape enables some cell motion (using structures such as flagella and cilia) and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments microfilaments microtubules and the microtrabecular lattice. www.broad.mit.e...
Broad PROTEASOME_COMPLEX View Gene Set 7.5e-05 23 0.0004988 35 Genes annotated by the GO term GO:0000502. A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. www.broad.mit.e...
Broad KINETOCHORE View Gene Set 7.922e-05 25 0.0004988 35 Genes annotated by the GO term GO:0000776. A multisubunit complex that is located at the pericentric region of DNA and provides an attachment point for the spindle microtubules. www.broad.mit.e...
Broad TRANSCRIPTION_FACTOR_COMPLEX View Gene Set 0.0001137 84 0.0006974 38 Genes annotated by the GO term GO:0005667. Any complex distinct from RNA polymerase including one or more polypeptides capable of binding DNA at promoters or at cis-acting regulatory sequences and regulating transcription. www.broad.mit.e...
Broad NUCLEAR_ENVELOPE View Gene Set 0.0001755 71 0.001048 39 Genes annotated by the GO term GO:0005635. The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space a gap of width 20-40 nm (also called the perinuclear space). www.broad.mit.e...
Broad MICROTUBULE View Gene Set 0.0001945 31 0.001133 40 Genes annotated by the GO term GO:0005874. Any of the long generally straight hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation e.g. in the spindle. www.broad.mit.e...
Broad NUCLEAR_PORE View Gene Set 0.0003534 29 0.00198 41 Genes annotated by the GO term GO:0005643. Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell where the inner and outer nuclear membranes are joined. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE_PART View Gene Set 0.0003569 40 0.00198 41 Genes annotated by the GO term GO:0044453. Any constituent part of the nuclear membrane the envelope that surrounds the nucleus of eukaryotic cells. www.broad.mit.e...
Broad SPINDLE_MICROTUBULE View Gene Set 0.0004316 15 0.002339 43 Genes annotated by the GO term GO:0005876. Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. www.broad.mit.e...
Broad PORE_COMPLEX View Gene Set 0.0004614 34 0.002443 44 Genes annotated by the GO term GO:0046930. Any small opening in a membrane that allows the passage of gases and/or liquids. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE View Gene Set 0.0007455 48 0.00386 45 Genes annotated by the GO term GO:0031965. Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. www.broad.mit.e...
Broad MITOCHONDRIAL_MATRIX View Gene Set 0.001093 46 0.005418 46 Genes annotated by the GO term GO:0005759. The gel-like material with considerable fine structure that lies in the matrix space or lumen of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and in some organisms the enzymes concerned with fatty-acid oxidation. www.broad.mit.e...
Broad MITOCHONDRIAL_LUMEN View Gene Set 0.001093 46 0.005418 46 Genes annotated by the GO term GO:0031980. The volume enclosed by the mitochondrial inner membrane. www.broad.mit.e...
Broad CONDENSED_NUCLEAR_CHROMOSOME View Gene Set 0.001234 17 0.005992 48 Genes annotated by the GO term GO:0000794. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure that remains in the nucleus. www.broad.mit.e...
Broad MITOCHONDRIAL_OUTER_MEMBRANE View Gene Set 0.001436 18 0.00683 49 Genes annotated by the GO term GO:0005741. The outer i.e. cytoplasm-facing lipid bilayer of the mitochondrial envelope. www.broad.mit.e...
Broad NUCLEAR_CHROMOSOME View Gene Set 0.001716 53 0.007998 50 Genes annotated by the GO term GO:0000228. A chromosome found in the nucleus of a eukaryotic cell. www.broad.mit.e...
Broad NUCLEAR_CHROMOSOME_PART View Gene Set 0.001936 33 0.008843 51 Genes annotated by the GO term GO:0044454. Any constituent part of a nuclear chromosome a chromosome found in the nucleus of a eukaryotic cell. www.broad.mit.e...
Broad SPINDLE_POLE View Gene Set 0.002125 17 0.009376 52 Genes annotated by the GO term GO:0000922. Either of the ends of a spindle where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules spindle microtubules and astral microtubules. www.broad.mit.e...
Broad ORGANELLE_OUTER_MEMBRANE View Gene Set 0.002133 24 0.009376 52 Genes annotated by the GO term GO:0031968. The outer i.e. cytoplasm-facing lipid bilayer of an organelle envelope. www.broad.mit.e...
Broad OUTER_MEMBRANE View Gene Set 0.002178 25 0.009398 54 Genes annotated by the GO term GO:0019867. The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. www.broad.mit.e...
Broad ORGANELLAR_RIBOSOME View Gene Set 0.002367 22 0.009847 55 Genes annotated by the GO term GO:0000313. A ribosome contained within a subcellular organelle. www.broad.mit.e...
Broad MITOCHONDRIAL_RIBOSOME View Gene Set 0.002367 22 0.009847 55 Genes annotated by the GO term GO:0005761. A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. www.broad.mit.e...
Broad EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX View Gene Set 0.00443 10 0.01811 57 Genes annotated by the GO term GO:0005852. A complex of several polypeptides that plays at least two important roles in protein synthesis: First eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. www.broad.mit.e...
Broad HETEROGENEOUS_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX View Gene Set 0.004811 9 0.01933 58 Genes annotated by the GO term GO:0030530. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II that which is translated into protein) with protein which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA. www.broad.mit.e...
Broad CYTOSKELETON View Gene Set 0.005586 359 0.02206 59 Genes annotated by the GO term GO:0005856. Any of the various filamentous elements that form the internal framework of cells and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments microfilaments microtubules the microtrabecular lattice and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions including cellular movement cell division endocytosis and movement of organelles. www.broad.mit.e...
Broad NUCLEOLAR_PART View Gene Set 0.006167 16 0.02395 60 Genes annotated by the GO term GO:0044452. Any constituent part of a nucleolus a small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. www.broad.mit.e...
Broad MICROTUBULE_ORGANIZING_CENTER_PART View Gene Set 0.00797 19 0.03044 61 Genes annotated by the GO term GO:0044450. Any constituent part of a microtubule organizing center a region in a eukaryotic cell such as a centrosome or basal body from which microtubules grow. www.broad.mit.e...
Broad KINESIN_COMPLEX View Gene Set 0.009222 14 0.03466 62 Genes annotated by the GO term GO:0005871. Any complex that includes a dimer of molecules from the kinesin superfamily a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity or motor which converts the free energy of the gamma phosphate bond of ATP into mechanical work. www.broad.mit.e...
Broad RIBOSOMAL_SUBUNIT View Gene Set 0.009643 20 0.03566 63 Genes annotated by the GO term GO:0033279. Either of the two ribonucleoprotein complexes that associate to form a ribosome. www.broad.mit.e...

Gene Set Collection: Broad.c5.MF

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad RNA_BINDING View Gene Set 3.638e-08 236 1.441e-05 1 Genes annotated by the GO term GO:0003723. Interacting selectively with an RNA molecule or a portion thereof. www.broad.mit.e...
Broad RNA_SPLICING_FACTOR_ACTIVITYTRANSESTERIFICATION_MECHANISM View Gene Set 3.669e-05 14 0.004843 2 Genes annotated by the GO term GO:0031202. An activity which binds RNA and functions to assist splicing of substrate RNA(s) by facilitating the formation and stabilization of a catalytic conformation in which the splice junctions of the RNA(s) to be spliced are positioned for a transesterification reaction that occurs between two sites within the RNA(s) to be spliced. www.broad.mit.e...
Broad HELICASE_ACTIVITY View Gene Set 3.195e-05 49 0.004843 2 Genes annotated by the GO term GO:0004386. Catalysis of the unwinding of a DNA or RNA duplex. www.broad.mit.e...
Broad RNA_HELICASE_ACTIVITY View Gene Set 0.0002794 24 0.0214 4 Genes annotated by the GO term GO:0003724. Catalysis of the unwinding of an RNA helix. www.broad.mit.e...
Broad ATP_DEPENDENT_HELICASE_ACTIVITY View Gene Set 0.0002842 26 0.0214 4 Genes annotated by the GO term GO:0008026. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the unwinding of a DNA or RNA helix. www.broad.mit.e...
Broad RNA_DEPENDENT_ATPASE_ACTIVITY View Gene Set 0.0003243 18 0.0214 4 Genes annotated by the GO term GO:0008186. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of RNA; drives another reaction. www.broad.mit.e...
Broad ATP_DEPENDENT_RNA_HELICASE_ACTIVITY View Gene Set 0.0004821 17 0.02727 7 Genes annotated by the GO term GO:0004004. Catalysis of the reaction: ATP + H2O = ADP + phosphate driving the unwinding of an RNA helix. www.broad.mit.e...
Broad TRANSLATION_INITIATION_FACTOR_ACTIVITY View Gene Set 0.000711 24 0.0352 8 Genes annotated by the GO term GO:0003743. Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. www.broad.mit.e...
Broad STRUCTURE_SPECIFIC_DNA_BINDING View Gene Set 0.0009038 55 0.03977 9 Genes annotated by the GO term GO:0043566. Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. www.broad.mit.e...

Gene Set Collection: OMIM

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
OMIM 256000 View Gene Set 7.864e-05 12 0.03696 1 256000 LEIGH SYNDROME; LS www.ncbi.nlm.ni...

Gene Set Collection: PMID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
PMID 15635413 View Gene Set 9.196e-28 421 2.306e-24 1 Nucleolar proteome dynamics. www.ncbi.nlm.ni...
PMID 12226669 View Gene Set 2.283e-19 108 2.862e-16 2 Comprehensive proteomic analysis of the human spliceosome. www.ncbi.nlm.ni...
PMID 11790298 View Gene Set 8.801e-19 208 7.355e-16 3 Directed proteomic analysis of the human nucleolus. www.ncbi.nlm.ni...
PMID 16565220 View Gene Set 1.352e-18 210 8.471e-16 4 Phosphoproteome analysis of the human mitotic spindle. www.ncbi.nlm.ni...
PMID 17643375 View Gene Set 1.513e-16 391 7.584e-14 5 Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. www.ncbi.nlm.ni...
PMID 12429849 View Gene Set 5.93e-14 106 2.478e-11 6 Functional proteomic analysis of human nucleolus. www.ncbi.nlm.ni...
PMID 15302935 View Gene Set 9.736e-14 773 3.487e-11 7 Large-scale characterization of HeLa cell nuclear phosphoproteins. www.ncbi.nlm.ni...
PMID 16964243 View Gene Set 9.922e-13 504 3.109e-10 8 A probability-based approach for high-throughput protein phosphorylation analysis and site localization. www.ncbi.nlm.ni...
PMID 11991638 View Gene Set 2.802e-11 74 7.025e-09 9 Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. www.ncbi.nlm.ni...
PMID 12706105 View Gene Set 2.65e-11 182 7.025e-09 9 Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. www.ncbi.nlm.ni...
PMID 12791985 View Gene Set 1.432e-10 37 3.264e-08 11 Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. www.ncbi.nlm.ni...
PMID 15231747 View Gene Set 5.858e-10 212 1.224e-07 12 A protein interaction framework for human mRNA degradation. www.ncbi.nlm.ni...
PMID 14559993 View Gene Set 3.628e-09 51 6.997e-07 13 Regulation of alternative splicing by SRrp86 and its interacting proteins. www.ncbi.nlm.ni...
PMID 11543634 View Gene Set 4.044e-09 58 7.242e-07 14 The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. www.ncbi.nlm.ni...
PMID 12221128 View Gene Set 5.389e-09 70 9.008e-07 15 Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex. www.ncbi.nlm.ni...
PMID 20496165 View Gene Set 6.787e-09 68 1.063e-06 16 Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. www.ncbi.nlm.ni...
PMID 11285280 View Gene Set 9.558e-09 62 1.41e-06 17 Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. www.ncbi.nlm.ni...
PMID 11076968 View Gene Set 1.592e-08 62 1.901e-06 18 The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion. www.ncbi.nlm.ni...
PMID 12852856 View Gene Set 1.592e-08 61 1.901e-06 18 Polo-like kinase 1 regulates Nlp a centrosome protein involved in microtubule nucleation. www.ncbi.nlm.ni...
PMID 16462731 View Gene Set 1.592e-08 62 1.901e-06 18 The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation. www.ncbi.nlm.ni...
PMID 7790358 View Gene Set 1.592e-08 61 1.901e-06 18 Cell cycle regulation of the activity and subcellular localization of Plk1 a human protein kinase implicated in mitotic spindle function. www.ncbi.nlm.ni...
PMID 18162579 View Gene Set 1.781e-08 22 2.029e-06 22 Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. www.ncbi.nlm.ni...
PMID 19237606 View Gene Set 1.993e-08 84 2.173e-06 23 Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. www.ncbi.nlm.ni...
PMID 12791267 View Gene Set 2.386e-08 50 2.493e-06 24 Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. www.ncbi.nlm.ni...
PMID 12234937 View Gene Set 4.088e-08 34 4.099e-06 25 Characterization of novel SF3b and 17S U2 snRNP proteins including a human Prp5p homologue and an SF3b DEAD-box protein. www.ncbi.nlm.ni...
PMID 12171929 View Gene Set 4.604e-08 31 4.44e-06 26 A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. www.ncbi.nlm.ni...
PMID 20508983 View Gene Set 7.605e-08 102 7.062e-06 27 Centrosome-related genes genetic variation and risk of breast cancer. www.ncbi.nlm.ni...
PMID 16622419 View Gene Set 8.001e-08 16 7.163e-06 28 The human CENP-A centromeric nucleosome-associated complex. www.ncbi.nlm.ni...
PMID 15009096 View Gene Set 1.119e-07 39 9.546e-06 29 Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex while BMI-1 is transiently co-localized with the centromeric region in interphase. www.ncbi.nlm.ni...
PMID 20522537 View Gene Set 1.142e-07 73 9.546e-06 29 Variation within DNA repair pathway genes and risk of multiple sclerosis. www.ncbi.nlm.ni...
PMID 15029244 View Gene Set 1.384e-07 57 1.119e-05 31 Mammalian Cdh1/Fzr mediates its own degradation. www.ncbi.nlm.ni...
PMID 14966270 View Gene Set 3.478e-07 19 2.553e-05 32 Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. www.ncbi.nlm.ni...
PMID 15146077 View Gene Set 3.564e-07 32 2.553e-05 32 The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. www.ncbi.nlm.ni...
PMID 15592455 View Gene Set 3.261e-07 317 2.553e-05 32 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. www.ncbi.nlm.ni...
PMID 16622420 View Gene Set 3.44e-07 14 2.553e-05 32 The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. www.ncbi.nlm.ni...
PMID 12167863 View Gene Set 7.8e-07 43 3.492e-05 36 Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. www.ncbi.nlm.ni...
PMID 12719574 View Gene Set 6.6e-07 42 3.492e-05 36 Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions. www.ncbi.nlm.ni...
PMID 12750511 View Gene Set 6.6e-07 42 3.492e-05 36 Hypermutation of HIV-1 DNA in the absence of the Vif protein. www.ncbi.nlm.ni...
PMID 12808465 View Gene Set 7.8e-07 43 3.492e-05 36 The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. www.ncbi.nlm.ni...
PMID 12808466 View Gene Set 7.8e-07 43 3.492e-05 36 Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. www.ncbi.nlm.ni...
PMID 12809610 View Gene Set 7.8e-07 43 3.492e-05 36 DNA deamination mediates innate immunity to retroviral infection. www.ncbi.nlm.ni...
PMID 12830140 View Gene Set 6.6e-07 42 3.492e-05 36 DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses. www.ncbi.nlm.ni...
PMID 12840737 View Gene Set 6.6e-07 42 3.492e-05 36 Good to CU. www.ncbi.nlm.ni...
PMID 12914693 View Gene Set 6.6e-07 42 3.492e-05 36 Death by deamination: a novel host restriction system for HIV-1. www.ncbi.nlm.ni...
PMID 12920286 View Gene Set 6.6e-07 42 3.492e-05 36 Virology. Weapons of mutational destruction. www.ncbi.nlm.ni...
PMID 12970355 View Gene Set 7.8e-07 43 3.492e-05 36 The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity. www.ncbi.nlm.ni...
PMID 14527406 View Gene Set 7.8e-07 43 3.492e-05 36 HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. www.ncbi.nlm.ni...
PMID 14528300 View Gene Set 7.8e-07 43 3.492e-05 36 The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. www.ncbi.nlm.ni...
PMID 14528301 View Gene Set 7.8e-07 43 3.492e-05 36 HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. www.ncbi.nlm.ni...
PMID 14557625 View Gene Set 7.8e-07 43 3.492e-05 36 The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15) a cellular inhibitor of virus infectivity. www.ncbi.nlm.ni...
PMID 14564014 View Gene Set 6.193e-07 47 3.492e-05 36 Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. www.ncbi.nlm.ni...
PMID 14614829 View Gene Set 6.6e-07 42 3.492e-05 36 The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G. www.ncbi.nlm.ni...
PMID 17363900 View Gene Set 5.578e-07 14 3.492e-05 36 The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. www.ncbi.nlm.ni...
PMID 19468067 View Gene Set 7.39e-07 10 3.492e-05 36 Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. www.ncbi.nlm.ni...
PMID 9811770 View Gene Set 6.6e-07 42 3.492e-05 36 An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein. www.ncbi.nlm.ni...
PMID 9846577 View Gene Set 6.6e-07 42 3.492e-05 36 Evidence for a newly discovered cellular anti-HIV-1 phenotype. www.ncbi.nlm.ni...
PMID 10893419 View Gene Set 8.388e-07 41 3.505e-05 57 Degradation of HIV-1 integrase by the N-end rule pathway. www.ncbi.nlm.ni...
PMID 12419264 View Gene Set 8.388e-07 41 3.505e-05 57 The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing. www.ncbi.nlm.ni...
PMID 14550573 View Gene Set 8.388e-07 41 3.505e-05 57 Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits. www.ncbi.nlm.ni...
PMID 9079628 View Gene Set 8.388e-07 41 3.505e-05 57 HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation. www.ncbi.nlm.ni...
PMID 18270339 View Gene Set 9.991e-07 57 4.106e-05 61 Comprehensive analysis of DNA repair gene variants and risk of meningioma. www.ncbi.nlm.ni...
PMID 12614612 View Gene Set 1.17e-06 19 4.731e-05 62 Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. www.ncbi.nlm.ni...
PMID 15707391 View Gene Set 1.276e-06 23 5.079e-05 63 DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. www.ncbi.nlm.ni...
PMID 12859895 View Gene Set 2.983e-06 47 0.0001169 64 Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. www.ncbi.nlm.ni...
PMID 11279123 View Gene Set 3.527e-06 31 0.000136 65 The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 19596235 View Gene Set 3.755e-06 85 0.0001426 66 Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. www.ncbi.nlm.ni...
PMID 8811196 View Gene Set 5.246e-06 37 0.0001963 67 Structure and functions of the 20S and 26S proteasomes. www.ncbi.nlm.ni...
PMID 9731529 View Gene Set 7.563e-06 24 0.0002788 68 Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. www.ncbi.nlm.ni...
PMID 15226314 View Gene Set 7.966e-06 20 0.0002894 69 Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. www.ncbi.nlm.ni...
PMID 11095689 View Gene Set 8.418e-06 17 0.0003015 70 The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase. www.ncbi.nlm.ni...
PMID 16236267 View Gene Set 1.047e-05 77 0.0003696 71 Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. www.ncbi.nlm.ni...
PMID 14667819 View Gene Set 1.592e-05 112 0.0005542 72 Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. www.ncbi.nlm.ni...
PMID 20085707 View Gene Set 1.818e-05 42 0.0006242 73 Aire's partners in the molecular control of immunological tolerance. www.ncbi.nlm.ni...
PMID 19209188 View Gene Set 1.933e-05 13 0.0006549 74 Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study. www.ncbi.nlm.ni...
PMID 10601273 View Gene Set 1.967e-05 21 0.0006577 75 Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein whereas export is due to a nuclear export signal sequence in glucokinase. www.ncbi.nlm.ni...
PMID 16716197 View Gene Set 2.27e-05 10 0.0007489 76 Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. www.ncbi.nlm.ni...
PMID 19710015 View Gene Set 2.483e-05 48 0.0008085 77 The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor. www.ncbi.nlm.ni...
PMID 10608806 View Gene Set 2.811e-05 25 0.0009035 78 Substrate specificities and identification of putative substrates of ATM kinase family members. www.ncbi.nlm.ni...
PMID 15196461 View Gene Set 2.853e-05 11 0.0009052 79 The highly conserved and multifunctional NuA4 HAT complex. www.ncbi.nlm.ni...
PMID 15504738 View Gene Set 2.896e-05 19 0.0009076 80 Genes affecting the cell cycle growth maintenance and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. www.ncbi.nlm.ni...
PMID 11812149 View Gene Set 3.084e-05 13 0.0009545 81 Protein-protein interactions of hCsl4p with other human exosome subunits. www.ncbi.nlm.ni...
PMID 11719186 View Gene Set 3.492e-05 17 0.001068 82 AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. www.ncbi.nlm.ni...
PMID 12963728 View Gene Set 3.575e-05 21 0.00108 83 Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. www.ncbi.nlm.ni...
PMID 11829477 View Gene Set 5.036e-05 13 0.001503 84 Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex. www.ncbi.nlm.ni...
PMID 12045100 View Gene Set 5.379e-05 18 0.001586 85 DNA replication in eukaryotic cells. www.ncbi.nlm.ni...
PMID 15647280 View Gene Set 5.65e-05 17 0.001647 86 The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. www.ncbi.nlm.ni...
PMID 20226869 View Gene Set 5.803e-05 25 0.001672 87 Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations. www.ncbi.nlm.ni...
PMID 12228227 View Gene Set 6.026e-05 30 0.001717 88 Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1. www.ncbi.nlm.ni...
PMID 10436018 View Gene Set 6.75e-05 15 0.00188 89 The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells. www.ncbi.nlm.ni...
PMID 18954305 View Gene Set 6.692e-05 13 0.00188 89 Structural basis and specificity of human otubain 1-mediated deubiquitination. www.ncbi.nlm.ni...
PMID 15130578 View Gene Set 7.479e-05 22 0.00206 91 Why do cells need an assembly machine for RNA-protein complexes? www.ncbi.nlm.ni...
PMID 11500380 View Gene Set 0.000103 10 0.002776 92 A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. www.ncbi.nlm.ni...
PMID 12419256 View Gene Set 0.0001023 12 0.002776 92 Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring. www.ncbi.nlm.ni...
PMID 11110791 View Gene Set 0.0001047 12 0.002793 94 Three novel components of the human exosome. www.ncbi.nlm.ni...
PMID 18427977 View Gene Set 0.0001085 17 0.002805 95 High-throughput multiplex single-nucleotide polymorphism (SNP) analysis in genes involved in methionine metabolism. www.ncbi.nlm.ni...
PMID 18635682 View Gene Set 0.0001085 17 0.002805 95 Genetic analysis of 56 polymorphisms in 17 genes involved in methionine metabolism in patients with abdominal aortic aneurysm. www.ncbi.nlm.ni...
PMID 20458436 View Gene Set 0.0001085 17 0.002805 95 Early-onset ischaemic stroke: analysis of 58 polymorphisms in 17 genes involved in methionine metabolism. www.ncbi.nlm.ni...
PMID 11416179 View Gene Set 0.0001167 12 0.002986 98 All kinesin superfamily protein KIF genes in mouse and human. www.ncbi.nlm.ni...
PMID 11125146 View Gene Set 0.0001215 10 0.003078 99 Inhibition of eukaryotic DNA replication by geminin binding to Cdt1. www.ncbi.nlm.ni...
PMID 19536649 View Gene Set 0.0001292 15 0.00324 100 The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features. www.ncbi.nlm.ni...
PMID 12930902 View Gene Set 0.0001424 11 0.003535 101 The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. www.ncbi.nlm.ni...
PMID 14743216 View Gene Set 0.0001458 132 0.003583 102 A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. www.ncbi.nlm.ni...
PMID 11310559 View Gene Set 0.0001587 17 0.003862 103 Identification of nuclear-import and cell-cycle regulatory proteins that bind to prothymosin alpha. www.ncbi.nlm.ni...
PMID 15691386 View Gene Set 0.0001662 12 0.003968 104 HIV-1 Tat protein enhances microtubule polymerization. www.ncbi.nlm.ni...
PMID 15698476 View Gene Set 0.0001662 12 0.003968 104 HIV-1 Tat apoptosis and the mitochondria: a tubulin link? www.ncbi.nlm.ni...
PMID 16195237 View Gene Set 0.0001924 20 0.00455 106 Polymorphisms of DNA repair genes and risk of non-small cell lung cancer. www.ncbi.nlm.ni...
PMID 16359901 View Gene Set 0.0002312 14 0.005417 107 Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. www.ncbi.nlm.ni...
PMID 9878398 View Gene Set 0.0002741 13 0.006363 108 Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. www.ncbi.nlm.ni...
PMID 17148452 View Gene Set 0.0002769 87 0.006368 109 Characterization of the interactome of the human MutL homologues MLH1 PMS1 and PMS2. www.ncbi.nlm.ni...
PMID 19690177 View Gene Set 0.0003196 31 0.007283 110 Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk. www.ncbi.nlm.ni...
PMID 10851237 View Gene Set 0.0003295 11 0.007374 111 Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). www.ncbi.nlm.ni...
PMID 11931757 View Gene Set 0.0003292 22 0.007374 111 Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. www.ncbi.nlm.ni...
PMID 12788944 View Gene Set 0.0003483 11 0.007728 113 The association of the human PM/Scl-75 autoantigen with the exosome is dependent on a newly identified N terminus. www.ncbi.nlm.ni...
PMID 11714716 View Gene Set 0.0004094 13 0.008924 114 Gemin5 a novel WD repeat protein component of the SMN complex that binds Sm proteins. www.ncbi.nlm.ni...
PMID 19858780 View Gene Set 0.0004081 10 0.008924 114 Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis. www.ncbi.nlm.ni...
PMID 9852112 View Gene Set 0.0004324 20 0.009345 116 Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes. www.ncbi.nlm.ni...
PMID 18206972 View Gene Set 0.0004517 12 0.009678 117 A TFTC/STAGA module mediates histone H2A and H2B deubiquitination coactivates nuclear receptors and counteracts heterochromatin silencing. www.ncbi.nlm.ni...
PMID 7494303 View Gene Set 0.0004556 12 0.009679 118 Mutational analysis of cell cycle arrest nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr. www.ncbi.nlm.ni...
PMID 10766737 View Gene Set 0.0004968 11 0.01047 119 Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. www.ncbi.nlm.ni...
PMID 14654843 View Gene Set 0.0005177 26 0.01082 120 Proteomic characterization of the human centrosome by protein correlation profiling. www.ncbi.nlm.ni...
PMID 9878551 View Gene Set 0.0005846 34 0.01211 121 cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. www.ncbi.nlm.ni...
PMID 11205743 View Gene Set 0.0005981 15 0.01219 122 Polo-like kinase interacts with proteasomes and regulates their activity. www.ncbi.nlm.ni...
PMID 18063578 View Gene Set 0.0005965 31 0.01219 122 The layered structure of human mitochondrial DNA nucleoids. www.ncbi.nlm.ni...
PMID 10531003 View Gene Set 0.0006131 15 0.0122 124 Newly assembled snRNPs associate with coiled bodies before speckles suggesting a nuclear snRNP maturation pathway. www.ncbi.nlm.ni...
PMID 17891500 View Gene Set 0.0006101 10 0.0122 124 One-carbon metabolism gene polymorphisms and risk of non-Hodgkin lymphoma in Australia. www.ncbi.nlm.ni...
PMID 8590280 View Gene Set 0.0006127 41 0.0122 124 Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. www.ncbi.nlm.ni...
PMID 15502821 View Gene Set 0.0007261 12 0.01433 127 A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. www.ncbi.nlm.ni...
PMID 12601814 View Gene Set 0.0007381 12 0.01446 128 Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis. www.ncbi.nlm.ni...
PMID 11157797 View Gene Set 0.0007834 76 0.01523 129 Sequence structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. www.ncbi.nlm.ni...
PMID 15078818 View Gene Set 0.0008059 11 0.01542 130 Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo. www.ncbi.nlm.ni...
PMID 16702407 View Gene Set 0.0008059 11 0.01542 130 DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A. www.ncbi.nlm.ni...
PMID 11713266 View Gene Set 0.0008237 12 0.01564 132 The methylosome a 20S complex containing JBP1 and pICln produces dimethylarginine-modified Sm proteins. www.ncbi.nlm.ni...
PMID 15386022 View Gene Set 0.0008325 16 0.01569 133 Role of histone H2A ubiquitination in Polycomb silencing. www.ncbi.nlm.ni...
PMID 11551941 View Gene Set 0.0008425 26 0.01576 134 The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 9121429 View Gene Set 0.0008504 39 0.01579 135 The human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzyme. www.ncbi.nlm.ni...
PMID 11748230 View Gene Set 0.0008782 17 0.01608 136 Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. www.ncbi.nlm.ni...
PMID 18830263 View Gene Set 0.0008789 36 0.01608 136 Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma. www.ncbi.nlm.ni...
PMID 11531413 View Gene Set 0.0009035 27 0.01641 138 HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25. www.ncbi.nlm.ni...
PMID 11799066 View Gene Set 0.0009348 21 0.01686 139 Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. www.ncbi.nlm.ni...
PMID 10983978 View Gene Set 0.0009598 10 0.01719 140 Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. www.ncbi.nlm.ni...
PMID 9111189 View Gene Set 0.0009765 16 0.01736 141 Which DNA polymerases are used for DNA-repair in eukaryotes? www.ncbi.nlm.ni...
PMID 11060040 View Gene Set 0.001022 15 0.01791 142 Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. www.ncbi.nlm.ni...
PMID 15070733 View Gene Set 0.001019 16 0.01791 142 M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP. www.ncbi.nlm.ni...
PMID 20516191 View Gene Set 0.00104 12 0.0181 144 A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins). www.ncbi.nlm.ni...
PMID 14499622 View Gene Set 0.001087 53 0.01879 145 Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation cell signaling oxidative metabolism and cellular transport. www.ncbi.nlm.ni...
PMID 15324660 View Gene Set 0.001113 242 0.01911 146 Proteomic functional and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. www.ncbi.nlm.ni...
PMID 15331610 View Gene Set 0.001171 12 0.01997 147 The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis. www.ncbi.nlm.ni...
PMID 15461802 View Gene Set 0.001205 293 0.02042 148 A genome annotation-driven approach to cloning the human ORFeome. www.ncbi.nlm.ni...
PMID 19116388 View Gene Set 0.001267 37 0.02132 149 A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility. www.ncbi.nlm.ni...
PMID 9763677 View Gene Set 0.001326 15 0.02217 150 Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. www.ncbi.nlm.ni...
PMID 11013263 View Gene Set 0.001369 16 0.02272 151 A novel nuclear receptor corepressor complex N-CoR contains components of the mammalian SWI/SNF complex and the corepressor KAP-1. www.ncbi.nlm.ni...
PMID 20347428 View Gene Set 0.001564 14 0.02579 152 A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. www.ncbi.nlm.ni...
PMID 11101529 View Gene Set 0.001615 34 0.02647 153 Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. www.ncbi.nlm.ni...
PMID 16541024 View Gene Set 0.001699 12 0.02766 154 Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. www.ncbi.nlm.ni...
PMID 16387653 View Gene Set 0.001728 42 0.02772 155 ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. www.ncbi.nlm.ni...
PMID 9184228 View Gene Set 0.001736 21 0.02772 155 Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription. www.ncbi.nlm.ni...
PMID 9334327 View Gene Set 0.001736 21 0.02772 155 The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II. www.ncbi.nlm.ni...
PMID 12973351 View Gene Set 0.001751 12 0.02778 158 A novel ubiquitin ligase is deficient in Fanconi anemia. www.ncbi.nlm.ni...
PMID 15931389 View Gene Set 0.001921 12 0.03029 159 Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. www.ncbi.nlm.ni...
PMID 2288909 View Gene Set 0.001971 30 0.03089 160 Multiple genes encoding zinc finger domains are expressed in human T cells. www.ncbi.nlm.ni...
PMID 12065586 View Gene Set 0.002035 14 0.03169 161 Identification and characterization of Gemin7 a novel component of the survival of motor neuron complex. www.ncbi.nlm.ni...
PMID 18782753 View Gene Set 0.002065 45 0.03195 162 A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. www.ncbi.nlm.ni...
PMID 9674425 View Gene Set 0.002146 11 0.033 163 Histone-like TAFs within the PCAF histone acetylase complex. www.ncbi.nlm.ni...
PMID 15782160 View Gene Set 0.002213 26 0.03381 164 Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment. www.ncbi.nlm.ni...
PMID 8995409 View Gene Set 0.002238 11 0.03381 164 Conservation and diversity of eukaryotic translation initiation factor eIF3. www.ncbi.nlm.ni...
PMID 8995410 View Gene Set 0.002238 10 0.03381 164 The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170. www.ncbi.nlm.ni...
PMID 9822659 View Gene Set 0.002304 11 0.03458 167 Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3. www.ncbi.nlm.ni...
PMID 10601333 View Gene Set 0.002345 12 0.03478 168 Gemin3: A novel DEAD box protein that interacts with SMN the spinal muscular atrophy gene product and is a component of gems. www.ncbi.nlm.ni...
PMID 19450687 View Gene Set 0.002339 11 0.03478 168 High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes. www.ncbi.nlm.ni...
PMID 11112772 View Gene Set 0.00245 20 0.03614 170 DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation. www.ncbi.nlm.ni...
PMID 19270065 View Gene Set 0.002503 11 0.0367 171 MRE11 complex links RECQ5 helicase to sites of DNA damage. www.ncbi.nlm.ni...
PMID 19536092 View Gene Set 0.002587 55 0.0377 172 Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array. www.ncbi.nlm.ni...
PMID 10725331 View Gene Set 0.002614 14 0.03788 173 Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. www.ncbi.nlm.ni...
PMID 15146057 View Gene Set 0.002731 10 0.03935 174 The entire Nup107-160 complex including three new members is targeted as one entity to kinetochores in mitosis. www.ncbi.nlm.ni...
PMID 15096576 View Gene Set 0.00287 14 0.04112 175 Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex. www.ncbi.nlm.ni...
PMID 7811265 View Gene Set 0.002981 16 0.04246 176 Human proteasome subunits from 2-dimensional gels identified by partial sequencing. www.ncbi.nlm.ni...
PMID 10066804 View Gene Set 0.003085 24 0.04351 177 Tat-associated kinase (P-TEFb): a component of transcription preinitiation and elongation complexes. www.ncbi.nlm.ni...
PMID 17322308 View Gene Set 0.003106 13 0.04351 177 Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry. www.ncbi.nlm.ni...
PMID 18599441 View Gene Set 0.003106 13 0.04351 177 Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3. www.ncbi.nlm.ni...
PMID 18809582 View Gene Set 0.003178 25 0.04426 180 Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. www.ncbi.nlm.ni...
PMID 15057824 View Gene Set 0.003426 274 0.04745 181 The DNA sequence and biology of human chromosome 19. www.ncbi.nlm.ni...
PMID 10793135 View Gene Set 0.0035 18 0.04795 182 Mitotic regulation of the APC activator proteins CDC20 and CDH1. www.ncbi.nlm.ni...
PMID 10810093 View Gene Set 0.0035 151 0.04795 182 Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. www.ncbi.nlm.ni...

Gene Set Collection: ChromosomalTiles5Mb

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null chr16_0-5Mb View Gene Set 1.625e-05 113 0.01656 1 Genomic tile: chr16 ; 1-5000001 Mb genome.ucsc.edu...
Null chr17_80-85Mb View Gene Set 3.517e-05 37 0.01656 1 Genomic tile: chr17 ; 80000001-85000001 Mb genome.ucsc.edu...
Null chr8_145-150Mb View Gene Set 4.458e-05 33 0.01656 1 Genomic tile: chr8 ; 145000001-150000001 Mb genome.ucsc.edu...
Null chr17_77.5-82.5Mb View Gene Set 6.193e-05 54 0.01725 4 Genomic tile: chr17 ; 77500001-82500001 Mb genome.ucsc.edu...
Null chr16_67.5-72.5Mb View Gene Set 0.0001065 51 0.02018 5 Genomic tile: chr16 ; 67500001-72500001 Mb genome.ucsc.edu...
Null chr9_132.5-137.5Mb View Gene Set 0.0001087 53 0.02018 5 Genomic tile: chr9 ; 132500001-137500001 Mb genome.ucsc.edu...

Gene Set Collection: Prosite

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null PS50102 View Gene Set 2.463e-09 229 1.81e-06 1 RRM expasy.org/pros...
Null PS50082 View Gene Set 1.089e-07 233 2.667e-05 2 WD_REPEATS_2 expasy.org/pros...
Null PS50294 View Gene Set 8.49e-08 245 2.667e-05 2 WD_REPEATS_REGION expasy.org/pros...
Null PS00678 View Gene Set 1.51e-06 168 0.0002775 4 WD_REPEATS_1 expasy.org/pros...
Null PS50862 View Gene Set 8.012e-06 18 0.001178 5 AA_TRNA_LIGASE_II expasy.org/pros...
Null PS50805 View Gene Set 1.156e-05 415 0.001344 6 KRAB expasy.org/pros...
Null PS51194 View Gene Set 1.28e-05 113 0.001344 6 HELICASE_CTER expasy.org/pros...
Null PS51192 View Gene Set 2.184e-05 112 0.002007 8 HELICASE_ATP_BIND_1 expasy.org/pros...
Null PS50067 View Gene Set 6.068e-05 46 0.00446 9 KINESIN_MOTOR_DOMAIN2 expasy.org/pros...
Null PS50174 View Gene Set 5.829e-05 25 0.00446 9 G_PATCH expasy.org/pros...
Null PS00046 View Gene Set 0.0001022 21 0.006829 11 HISTONE_H2A expasy.org/pros...
Null PS51195 View Gene Set 0.0002494 37 0.01528 12 Q_MOTIF expasy.org/pros...
Null PS00411 View Gene Set 0.0002906 42 0.01643 13 KINESIN_MOTOR_DOMAIN1 expasy.org/pros...
Null PS00227 View Gene Set 0.0005514 26 0.02895 14 TUBULIN expasy.org/pros...
Null PS00178 View Gene Set 0.0008746 15 0.04285 15 AA_TRNA_LIGASE_I expasy.org/pros...

Gene Set Collection: ppi.BIND

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.E2F4 View Gene Set 4.336e-05 14 0.003788 1 Protein-protein-interaction for E2F4 www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 4.448e-05 7 0.003788 1 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.RAD51 View Gene Set 6.013e-05 7 0.003788 1 Protein-protein-interaction for RAD51 www.ncbi.nlm.ni...
Null ppi.E2F1 View Gene Set 0.0003572 12 0.01688 4 Protein-protein-interaction for E2F1 www.ncbi.nlm.ni...

Gene Set Collection: ppi.BioGRID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.155871 View Gene Set 1.617e-18 236 3.714e-15 1 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.SRRM2 View Gene Set 1.039e-11 101 1.193e-08 2 Protein-protein-interaction for SRRM2 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 4.747e-09 147 3.634e-06 3 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.SRRM1 View Gene Set 9.07e-08 64 5.208e-05 4 Protein-protein-interaction for SRRM1 www.ncbi.nlm.ni...
Null ppi.GPN1 View Gene Set 6.045e-07 27 0.0002777 5 Protein-protein-interaction for GPN1 www.ncbi.nlm.ni...
Null ppi.72462 View Gene Set 1.482e-06 42 0.0005674 6 Protein-protein-interaction for 72462 www.ncbi.nlm.ni...
Null ppi.RNU12-2P View Gene Set 2.266e-06 18 0.0006508 7 Protein-protein-interaction for RNU12-2P www.ncbi.nlm.ni...
Null ppi.RNU11 View Gene Set 2.266e-06 18 0.0006508 7 Protein-protein-interaction for RNU11 www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 6.455e-06 40 0.001647 9 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.USP36 View Gene Set 1.17e-05 17 0.002686 10 Protein-protein-interaction for USP36 www.ncbi.nlm.ni...
Null ppi.PSMD14 View Gene Set 1.339e-05 16 0.002796 11 Protein-protein-interaction for PSMD14 www.ncbi.nlm.ni...
Null ppi.CDT1 View Gene Set 1.545e-05 37 0.002958 12 Protein-protein-interaction for CDT1 www.ncbi.nlm.ni...
Null ppi.TP53BP1 View Gene Set 1.839e-05 13 0.00325 13 Protein-protein-interaction for TP53BP1 www.ncbi.nlm.ni...
Null ppi.RRP1B View Gene Set 2.1e-05 21 0.003445 14 Protein-protein-interaction for RRP1B www.ncbi.nlm.ni...
Null ppi.ORC6L View Gene Set 2.296e-05 11 0.003516 15 Protein-protein-interaction for ORC6L www.ncbi.nlm.ni...
Null ppi.FANCA View Gene Set 3.377e-05 14 0.004563 16 Protein-protein-interaction for FANCA www.ncbi.nlm.ni...
Null ppi.SF3B3 View Gene Set 3.234e-05 16 0.004563 16 Protein-protein-interaction for SF3B3 www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 3.653e-05 14 0.004661 18 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.TERF2 View Gene Set 3.982e-05 9 0.004814 19 Protein-protein-interaction for TERF2 www.ncbi.nlm.ni...
Null ppi.FEN1 View Gene Set 6.866e-05 11 0.007431 20 Protein-protein-interaction for FEN1 www.ncbi.nlm.ni...
Null ppi.HIST2H2AC View Gene Set 6.937e-05 13 0.007431 20 Protein-protein-interaction for HIST2H2AC www.ncbi.nlm.ni...
Null ppi.ATRIP View Gene Set 7.117e-05 9 0.007431 20 Protein-protein-interaction for ATRIP www.ncbi.nlm.ni...
Null ppi.MED26 View Gene Set 7.481e-05 22 0.007471 23 Protein-protein-interaction for MED26 www.ncbi.nlm.ni...
Null ppi.SMNDC1 View Gene Set 9.017e-05 8 0.00863 24 Protein-protein-interaction for SMNDC1 www.ncbi.nlm.ni...
Null ppi.UCHL5 View Gene Set 9.683e-05 33 0.008897 25 Protein-protein-interaction for UCHL5 www.ncbi.nlm.ni...
Null ppi.C20orf20 View Gene Set 0.0001052 15 0.009294 26 Protein-protein-interaction for C20orf20 www.ncbi.nlm.ni...
Null ppi.TH1L View Gene Set 0.0001214 26 0.009297 27 Protein-protein-interaction for TH1L www.ncbi.nlm.ni...
Null ppi.CHTF18 View Gene Set 0.0001194 13 0.009297 27 Protein-protein-interaction for CHTF18 www.ncbi.nlm.ni...
Null ppi.WDR77 View Gene Set 0.0001137 15 0.009297 27 Protein-protein-interaction for WDR77 www.ncbi.nlm.ni...
Null ppi.DPY30 View Gene Set 0.0001206 9 0.009297 27 Protein-protein-interaction for DPY30 www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 0.0001471 9 0.01056 31 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.RPA1 View Gene Set 0.0001431 23 0.01056 31 Protein-protein-interaction for RPA1 www.ncbi.nlm.ni...
Null ppi.HIST2H2BE View Gene Set 0.0001675 17 0.01166 33 Protein-protein-interaction for HIST2H2BE www.ncbi.nlm.ni...
Null ppi.PSMD6 View Gene Set 0.0001731 21 0.0117 34 Protein-protein-interaction for PSMD6 www.ncbi.nlm.ni...
Null ppi.ING3 View Gene Set 0.0002163 10 0.0142 35 Protein-protein-interaction for ING3 www.ncbi.nlm.ni...
Null ppi.PTCD3 View Gene Set 0.0002289 6 0.01421 36 Protein-protein-interaction for PTCD3 www.ncbi.nlm.ni...
Null ppi.MIS12 View Gene Set 0.0002254 9 0.01421 36 Protein-protein-interaction for MIS12 www.ncbi.nlm.ni...
Null ppi.WBP4 View Gene Set 0.0002522 35 0.01524 38 Protein-protein-interaction for WBP4 www.ncbi.nlm.ni...
Null ppi.LYAR View Gene Set 0.0003104 26 0.01828 39 Protein-protein-interaction for LYAR www.ncbi.nlm.ni...
Null ppi.CHD1L View Gene Set 0.0003581 15 0.02057 40 Protein-protein-interaction for CHD1L www.ncbi.nlm.ni...
Null ppi.MYSM1 View Gene Set 0.0003844 13 0.02106 41 Protein-protein-interaction for MYSM1 www.ncbi.nlm.ni...
Null ppi.PCNA View Gene Set 0.000385 40 0.02106 41 Protein-protein-interaction for PCNA www.ncbi.nlm.ni...
Null ppi.CHAF1A View Gene Set 0.0004251 19 0.02219 43 Protein-protein-interaction for CHAF1A www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 0.0004185 53 0.02219 43 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.CDCA8 View Gene Set 0.0004773 8 0.02309 45 Protein-protein-interaction for CDCA8 www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 0.0004684 11 0.02309 45 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.GIYD2 View Gene Set 0.0004824 32 0.02309 45 Protein-protein-interaction for GIYD2 www.ncbi.nlm.ni...
Null ppi.MED13 View Gene Set 0.0004576 10 0.02309 45 Protein-protein-interaction for MED13 www.ncbi.nlm.ni...
Null ppi.KHDRBS2 View Gene Set 0.0005263 46 0.02325 49 Protein-protein-interaction for KHDRBS2 www.ncbi.nlm.ni...
Null ppi.KAT2A View Gene Set 0.000504 12 0.02325 49 Protein-protein-interaction for KAT2A www.ncbi.nlm.ni...
Null ppi.PAAF1 View Gene Set 0.0005252 20 0.02325 49 Protein-protein-interaction for PAAF1 www.ncbi.nlm.ni...
Null ppi.MDC1 View Gene Set 0.0005208 20 0.02325 49 Protein-protein-interaction for MDC1 www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 0.0005638 43 0.02443 53 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.RNMTL1 View Gene Set 0.0006009 8 0.02556 54 Protein-protein-interaction for RNMTL1 www.ncbi.nlm.ni...
Null ppi.SF3A2 View Gene Set 0.0006448 16 0.02645 55 Protein-protein-interaction for SF3A2 www.ncbi.nlm.ni...
Null ppi.SUPT3H View Gene Set 0.0006345 14 0.02645 55 Protein-protein-interaction for SUPT3H www.ncbi.nlm.ni...
Null ppi.FANCD2 View Gene Set 0.000675 6 0.0272 57 Protein-protein-interaction for FANCD2 www.ncbi.nlm.ni...
Null ppi.FAM173A View Gene Set 0.0006901 10 0.02733 58 Protein-protein-interaction for FAM173A www.ncbi.nlm.ni...
Null ppi.SUMO2 View Gene Set 0.0007401 50 0.02881 59 Protein-protein-interaction for SUMO2 www.ncbi.nlm.ni...
Null ppi.RAD17 View Gene Set 0.0008056 13 0.03084 60 Protein-protein-interaction for RAD17 www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 0.0008422 19 0.0312 61 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.MRE11A View Gene Set 0.0008351 13 0.0312 61 Protein-protein-interaction for MRE11A www.ncbi.nlm.ni...
Null ppi.MUS81 View Gene Set 0.0008696 6 0.03171 63 Protein-protein-interaction for MUS81 www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 0.0009482 15 0.03351 64 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.EIF3B View Gene Set 0.000945 10 0.03351 64 Protein-protein-interaction for EIF3B www.ncbi.nlm.ni...
Null ppi.USP14 View Gene Set 0.001022 22 0.03558 66 Protein-protein-interaction for USP14 www.ncbi.nlm.ni...
Null ppi.GSTK1 View Gene Set 0.001062 26 0.03586 67 Protein-protein-interaction for GSTK1 www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 0.001052 24 0.03586 67 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.PPP4R2 View Gene Set 0.001136 7 0.03781 69 Protein-protein-interaction for PPP4R2 www.ncbi.nlm.ni...
Null ppi.RUVBL2 View Gene Set 0.001237 64 0.03848 70 Protein-protein-interaction for RUVBL2 www.ncbi.nlm.ni...
Null ppi.FANCM View Gene Set 0.001193 13 0.03848 70 Protein-protein-interaction for FANCM www.ncbi.nlm.ni...
Null ppi.RFC5 View Gene Set 0.00124 8 0.03848 70 Protein-protein-interaction for RFC5 www.ncbi.nlm.ni...
Null ppi.ATXN7 View Gene Set 0.001236 10 0.03848 70 Protein-protein-interaction for ATXN7 www.ncbi.nlm.ni...
Null ppi.USF2 View Gene Set 0.001207 13 0.03848 70 Protein-protein-interaction for USF2 www.ncbi.nlm.ni...
Null ppi.WWOX View Gene Set 0.001264 19 0.03872 75 Protein-protein-interaction for WWOX www.ncbi.nlm.ni...
Null ppi.POLR2C View Gene Set 0.001322 7 0.03985 76 Protein-protein-interaction for POLR2C www.ncbi.nlm.ni...
Null ppi.OTUD5 View Gene Set 0.001336 13 0.03985 76 Protein-protein-interaction for OTUD5 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 0.001354 12 0.03988 78 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.MCPH1 View Gene Set 0.001394 17 0.04053 79 Protein-protein-interaction for MCPH1 www.ncbi.nlm.ni...
Null ppi.PSMD13 View Gene Set 0.001529 20 0.04336 80 Protein-protein-interaction for PSMD13 www.ncbi.nlm.ni...
Null ppi.SNRPE View Gene Set 0.001517 7 0.04336 80 Protein-protein-interaction for SNRPE www.ncbi.nlm.ni...
Null ppi.854067 View Gene Set 0.001564 15 0.04381 82 Protein-protein-interaction for 854067 www.ncbi.nlm.ni...
Null ppi.SRSF9 View Gene Set 0.001639 6 0.04536 83 Protein-protein-interaction for SRSF9 www.ncbi.nlm.ni...
Null ppi.MCM7 View Gene Set 0.001691 11 0.04623 84 Protein-protein-interaction for MCM7 www.ncbi.nlm.ni...
Null ppi.BAZ1B View Gene Set 0.001737 30 0.04694 85 Protein-protein-interaction for BAZ1B www.ncbi.nlm.ni...
Null ppi.RAD50 View Gene Set 0.001863 20 0.04936 86 Protein-protein-interaction for RAD50 www.ncbi.nlm.ni...
Null ppi.RPA4 View Gene Set 0.00187 7 0.04936 86 Protein-protein-interaction for RPA4 www.ncbi.nlm.ni...

Gene Set Collection: ppi.HPRD

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.SFRS12 View Gene Set 8.094e-09 49 1.922e-05 1 Protein-protein-interaction for SFRS12 www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 7.119e-07 18 0.0008451 2 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 3.082e-05 13 0.01219 3 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.SUMO4 View Gene Set 2.331e-05 76 0.01219 3 Protein-protein-interaction for SUMO4 www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 3.077e-05 17 0.01219 3 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 2.798e-05 26 0.01219 3 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 9.322e-05 27 0.03162 7 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.NUP50 View Gene Set 0.0001151 6 0.03415 8 Protein-protein-interaction for NUP50 www.ncbi.nlm.ni...
Null ppi.RAD17 View Gene Set 0.0001688 9 0.04452 9 Protein-protein-interaction for RAD17 www.ncbi.nlm.ni...

Gene Set Collection: ppi.anyDB

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.155871 View Gene Set 1.123e-18 251 4.035e-15 1 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.SRRM2 View Gene Set 1.039e-11 101 1.866e-08 2 Protein-protein-interaction for SRRM2 www.ncbi.nlm.ni...
Null ppi.SFRS12 View Gene Set 3.366e-09 50 4.032e-06 3 Protein-protein-interaction for SFRS12 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 4.747e-09 147 4.265e-06 4 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.SRRM1 View Gene Set 1.444e-07 66 0.0001038 5 Protein-protein-interaction for SRRM1 www.ncbi.nlm.ni...
Null ppi.GPN1 View Gene Set 6.045e-07 27 0.0003621 6 Protein-protein-interaction for GPN1 www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 8.094e-07 20 0.0004156 7 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.72462 View Gene Set 1.482e-06 42 0.0006658 8 Protein-protein-interaction for 72462 www.ncbi.nlm.ni...
Null ppi.RNU12-2P View Gene Set 2.266e-06 18 0.0008146 9 Protein-protein-interaction for RNU12-2P www.ncbi.nlm.ni...
Null ppi.RNU11 View Gene Set 2.266e-06 18 0.0008146 9 Protein-protein-interaction for RNU11 www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 2.538e-06 16 0.0008293 11 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.CDT1 View Gene Set 3.896e-06 42 0.001167 12 Protein-protein-interaction for CDT1 www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 7.871e-06 52 0.002176 13 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.USP36 View Gene Set 1.17e-05 17 0.003002 14 Protein-protein-interaction for USP36 www.ncbi.nlm.ni...
Null ppi.PSMD14 View Gene Set 1.339e-05 16 0.003008 15 Protein-protein-interaction for PSMD14 www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 1.305e-05 21 0.003008 15 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 1.986e-05 33 0.004192 17 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.RRP1B View Gene Set 2.1e-05 21 0.004192 17 Protein-protein-interaction for RRP1B www.ncbi.nlm.ni...
Null ppi.SUMO4 View Gene Set 2.331e-05 76 0.00441 19 Protein-protein-interaction for SUMO4 www.ncbi.nlm.ni...
Null ppi.FANCA View Gene Set 3.377e-05 14 0.006068 20 Protein-protein-interaction for FANCA www.ncbi.nlm.ni...
Null ppi.ORC6L View Gene Set 3.565e-05 15 0.006102 21 Protein-protein-interaction for ORC6L www.ncbi.nlm.ni...
Null ppi.ING3 View Gene Set 3.918e-05 12 0.0064 22 Protein-protein-interaction for ING3 www.ncbi.nlm.ni...
Null ppi.SF3B3 View Gene Set 4.222e-05 19 0.006597 23 Protein-protein-interaction for SF3B3 www.ncbi.nlm.ni...
Null ppi.SMNDC1 View Gene Set 5.963e-05 10 0.008929 24 Protein-protein-interaction for SMNDC1 www.ncbi.nlm.ni...
Null ppi.C20orf20 View Gene Set 6.553e-05 16 0.009421 25 Protein-protein-interaction for C20orf20 www.ncbi.nlm.ni...
Null ppi.FEN1 View Gene Set 6.866e-05 11 0.009491 26 Protein-protein-interaction for FEN1 www.ncbi.nlm.ni...
Null ppi.TH1L View Gene Set 9.497e-05 29 0.01264 27 Protein-protein-interaction for TH1L www.ncbi.nlm.ni...
Null ppi.UCHL5 View Gene Set 0.0001184 34 0.0148 28 Protein-protein-interaction for UCHL5 www.ncbi.nlm.ni...
Null ppi.CHTF18 View Gene Set 0.0001194 13 0.0148 28 Protein-protein-interaction for CHTF18 www.ncbi.nlm.ni...
Null ppi.CDC20 View Gene Set 0.0001279 5 0.01533 30 Protein-protein-interaction for CDC20 www.ncbi.nlm.ni...
Null ppi.XRCC3 View Gene Set 0.0001397 6 0.01619 31 Protein-protein-interaction for XRCC3 www.ncbi.nlm.ni...
Null ppi.TP53BP1 View Gene Set 0.000157 17 0.01763 32 Protein-protein-interaction for TP53BP1 www.ncbi.nlm.ni...
Null ppi.FANCD2 View Gene Set 0.0002311 7 0.02443 33 Protein-protein-interaction for FANCD2 www.ncbi.nlm.ni...
Null ppi.MIS12 View Gene Set 0.0002254 9 0.02443 33 Protein-protein-interaction for MIS12 www.ncbi.nlm.ni...
Null ppi.RAD17 View Gene Set 0.000245 14 0.02515 35 Protein-protein-interaction for RAD17 www.ncbi.nlm.ni...
Null ppi.WBP4 View Gene Set 0.0002522 35 0.02517 36 Protein-protein-interaction for WBP4 www.ncbi.nlm.ni...
Null ppi.KHDRBS2 View Gene Set 0.0002749 48 0.02533 37 Protein-protein-interaction for KHDRBS2 www.ncbi.nlm.ni...
Null ppi.PCNA View Gene Set 0.0002727 47 0.02533 37 Protein-protein-interaction for PCNA www.ncbi.nlm.ni...
Null ppi.ATRIP View Gene Set 0.000273 13 0.02533 37 Protein-protein-interaction for ATRIP www.ncbi.nlm.ni...
Null ppi.KAT2A View Gene Set 0.0003078 14 0.02594 40 Protein-protein-interaction for KAT2A www.ncbi.nlm.ni...
Null ppi.NAA38 View Gene Set 0.0002974 28 0.02594 40 Protein-protein-interaction for NAA38 www.ncbi.nlm.ni...
Null ppi.LYAR View Gene Set 0.0003104 26 0.02594 40 Protein-protein-interaction for LYAR www.ncbi.nlm.ni...
Null ppi.TERF2 View Gene Set 0.0002991 10 0.02594 40 Protein-protein-interaction for TERF2 www.ncbi.nlm.ni...
Null ppi.MED26 View Gene Set 0.0003186 23 0.02603 44 Protein-protein-interaction for MED26 www.ncbi.nlm.ni...
Null ppi.E2F4 View Gene Set 0.0003461 16 0.02747 45 Protein-protein-interaction for E2F4 www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 0.0003668 21 0.02747 45 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.TP53BP2 View Gene Set 0.000365 17 0.02747 45 Protein-protein-interaction for TP53BP2 www.ncbi.nlm.ni...
Null ppi.CHD1L View Gene Set 0.0003581 15 0.02747 45 Protein-protein-interaction for CHD1L www.ncbi.nlm.ni...
Null ppi.THOC4 View Gene Set 0.000377 5 0.02747 49 Protein-protein-interaction for THOC4 www.ncbi.nlm.ni...
Null ppi.MYSM1 View Gene Set 0.0003844 13 0.02747 49 Protein-protein-interaction for MYSM1 www.ncbi.nlm.ni...
Null ppi.RAD1 View Gene Set 0.0003898 6 0.02747 49 Protein-protein-interaction for RAD1 www.ncbi.nlm.ni...
Null ppi.SGOL1 View Gene Set 0.0004404 24 0.02986 52 Protein-protein-interaction for SGOL1 www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 0.0004348 25 0.02986 52 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.TPX2 View Gene Set 0.0004745 5 0.03042 54 Protein-protein-interaction for TPX2 www.ncbi.nlm.ni...
Null ppi.CDCA8 View Gene Set 0.0004773 8 0.03042 54 Protein-protein-interaction for CDCA8 www.ncbi.nlm.ni...
Null ppi.GIYD2 View Gene Set 0.0004824 32 0.03042 54 Protein-protein-interaction for GIYD2 www.ncbi.nlm.ni...
Null ppi.PSMD6 View Gene Set 0.0004765 23 0.03042 54 Protein-protein-interaction for PSMD6 www.ncbi.nlm.ni...
Null ppi.HIST2H2AC View Gene Set 0.0005152 14 0.03193 58 Protein-protein-interaction for HIST2H2AC www.ncbi.nlm.ni...
Null ppi.PAAF1 View Gene Set 0.0005252 20 0.03199 59 Protein-protein-interaction for PAAF1 www.ncbi.nlm.ni...
Null ppi.EXOSC4 View Gene Set 0.0005632 21 0.03233 60 Protein-protein-interaction for EXOSC4 www.ncbi.nlm.ni...
Null ppi.SMURF1 View Gene Set 0.0005635 76 0.03233 60 Protein-protein-interaction for SMURF1 www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 0.0005638 43 0.03233 60 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.SRSF9 View Gene Set 0.0005668 8 0.03233 60 Protein-protein-interaction for SRSF9 www.ncbi.nlm.ni...
Null ppi.LSM2 View Gene Set 0.0005848 26 0.03239 64 Protein-protein-interaction for LSM2 www.ncbi.nlm.ni...
Null ppi.RPA1 View Gene Set 0.0005857 24 0.03239 64 Protein-protein-interaction for RPA1 www.ncbi.nlm.ni...
Null ppi.RNMTL1 View Gene Set 0.0006009 8 0.03272 66 Protein-protein-interaction for RNMTL1 www.ncbi.nlm.ni...
Null ppi.DNAJC7 View Gene Set 0.0006141 8 0.03294 67 Protein-protein-interaction for DNAJC7 www.ncbi.nlm.ni...
Null ppi.SF3A2 View Gene Set 0.0006448 16 0.03327 68 Protein-protein-interaction for SF3A2 www.ncbi.nlm.ni...
Null ppi.SUPT3H View Gene Set 0.0006345 14 0.03327 68 Protein-protein-interaction for SUPT3H www.ncbi.nlm.ni...
Null ppi.EIF2S2 View Gene Set 0.000648 17 0.03327 68 Protein-protein-interaction for EIF2S2 www.ncbi.nlm.ni...
Null ppi.XRN2 View Gene Set 0.0007018 9 0.03409 71 Protein-protein-interaction for XRN2 www.ncbi.nlm.ni...
Null ppi.KIF4A View Gene Set 0.000699 7 0.03409 71 Protein-protein-interaction for KIF4A www.ncbi.nlm.ni...
Null ppi.FAM173A View Gene Set 0.0006901 10 0.03409 71 Protein-protein-interaction for FAM173A www.ncbi.nlm.ni...
Null ppi.DSCC1 View Gene Set 0.0006843 6 0.03409 71 Protein-protein-interaction for DSCC1 www.ncbi.nlm.ni...
Null ppi.MLH1 View Gene Set 0.0007867 12 0.0372 75 Protein-protein-interaction for MLH1 www.ncbi.nlm.ni...
Null ppi.UBA1 View Gene Set 0.0007841 11 0.0372 75 Protein-protein-interaction for UBA1 www.ncbi.nlm.ni...
Null ppi.PDHX View Gene Set 0.0008063 7 0.03763 77 Protein-protein-interaction for PDHX www.ncbi.nlm.ni...
Null ppi.GTF2H2 View Gene Set 0.0008668 7 0.03828 78 Protein-protein-interaction for GTF2H2 www.ncbi.nlm.ni...
Null ppi.OTUD5 View Gene Set 0.0008517 14 0.03828 78 Protein-protein-interaction for OTUD5 www.ncbi.nlm.ni...
Null ppi.XRCC1 View Gene Set 0.0008735 11 0.03828 78 Protein-protein-interaction for XRCC1 www.ncbi.nlm.ni...
Null ppi.MUS81 View Gene Set 0.0008696 6 0.03828 78 Protein-protein-interaction for MUS81 www.ncbi.nlm.ni...
Null ppi.SIP1 View Gene Set 0.0008377 17 0.03828 78 Protein-protein-interaction for SIP1 www.ncbi.nlm.ni...
Null ppi.NUP50 View Gene Set 0.0008963 8 0.03881 83 Protein-protein-interaction for NUP50 www.ncbi.nlm.ni...
Null ppi.SF3A3 View Gene Set 0.0009953 8 0.04208 84 Protein-protein-interaction for SF3A3 www.ncbi.nlm.ni...
Null ppi.MCM7 View Gene Set 0.0009929 12 0.04208 84 Protein-protein-interaction for MCM7 www.ncbi.nlm.ni...
Null ppi.RAD50 View Gene Set 0.001021 21 0.04223 86 Protein-protein-interaction for RAD50 www.ncbi.nlm.ni...
Null ppi.USP14 View Gene Set 0.001022 22 0.04223 86 Protein-protein-interaction for USP14 www.ncbi.nlm.ni...
Null ppi.HSPH1 View Gene Set 0.001058 12 0.04287 88 Protein-protein-interaction for HSPH1 www.ncbi.nlm.ni...
Null ppi.GSTK1 View Gene Set 0.001062 26 0.04287 88 Protein-protein-interaction for GSTK1 www.ncbi.nlm.ni...
Null ppi.ATXN7 View Gene Set 0.00109 11 0.04307 90 Protein-protein-interaction for ATXN7 www.ncbi.nlm.ni...
Null ppi.BUB1B View Gene Set 0.00108 6 0.04307 90 Protein-protein-interaction for BUB1B www.ncbi.nlm.ni...
Null ppi.PPP4R2 View Gene Set 0.001136 7 0.04409 92 Protein-protein-interaction for PPP4R2 www.ncbi.nlm.ni...
Null ppi.XPO1 View Gene Set 0.001153 43 0.04409 92 Protein-protein-interaction for XPO1 www.ncbi.nlm.ni...
Null ppi.EIF3C View Gene Set 0.001151 9 0.04409 92 Protein-protein-interaction for EIF3C www.ncbi.nlm.ni...
Null ppi.FANCM View Gene Set 0.001193 13 0.04515 95 Protein-protein-interaction for FANCM www.ncbi.nlm.ni...
Null ppi.MRE11A View Gene Set 0.001232 16 0.04534 96 Protein-protein-interaction for MRE11A www.ncbi.nlm.ni...
Null ppi.PTMA View Gene Set 0.001249 21 0.04534 96 Protein-protein-interaction for PTMA www.ncbi.nlm.ni...
Null ppi.RFC5 View Gene Set 0.00124 8 0.04534 96 Protein-protein-interaction for RFC5 www.ncbi.nlm.ni...
Null ppi.TERF1 View Gene Set 0.00123 18 0.04534 96 Protein-protein-interaction for TERF1 www.ncbi.nlm.ni...
Null ppi.EIF3B View Gene Set 0.001281 11 0.04603 100 Protein-protein-interaction for EIF3B www.ncbi.nlm.ni...
Null ppi.POLR2C View Gene Set 0.001322 7 0.04703 101 Protein-protein-interaction for POLR2C www.ncbi.nlm.ni...
Null ppi.MED13 View Gene Set 0.001361 12 0.04796 102 Protein-protein-interaction for MED13 www.ncbi.nlm.ni...
Null ppi.NCOA6 View Gene Set 0.001434 61 0.04861 103 Protein-protein-interaction for NCOA6 www.ncbi.nlm.ni...
Null ppi.GEMIN5 View Gene Set 0.001422 14 0.04861 103 Protein-protein-interaction for GEMIN5 www.ncbi.nlm.ni...
Null ppi.MPP6 View Gene Set 0.001423 19 0.04861 103 Protein-protein-interaction for MPP6 www.ncbi.nlm.ni...
Null ppi.MCPH1 View Gene Set 0.001394 17 0.04861 103 Protein-protein-interaction for MCPH1 www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 0.001455 46 0.04886 107 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.PSMD13 View Gene Set 0.001529 20 0.04931 108 Protein-protein-interaction for PSMD13 www.ncbi.nlm.ni...
Null ppi.RAD51 View Gene Set 0.001549 20 0.04931 108 Protein-protein-interaction for RAD51 www.ncbi.nlm.ni...
Null ppi.SNRPE View Gene Set 0.001517 7 0.04931 108 Protein-protein-interaction for SNRPE www.ncbi.nlm.ni...
Null ppi.WDR77 View Gene Set 0.001564 18 0.04931 108 Protein-protein-interaction for WDR77 www.ncbi.nlm.ni...
Null ppi.HIST2H2BE View Gene Set 0.001521 27 0.04931 108 Protein-protein-interaction for HIST2H2BE www.ncbi.nlm.ni...
Null ppi.854067 View Gene Set 0.001564 15 0.04931 108 Protein-protein-interaction for 854067 www.ncbi.nlm.ni...
Null ppi.MDC1 View Gene Set 0.001557 24 0.04931 108 Protein-protein-interaction for MDC1 www.ncbi.nlm.ni...
Null ppi.AIMP2 View Gene Set 0.001587 13 0.04958 115 Protein-protein-interaction for AIMP2 www.ncbi.nlm.ni...

Gene Set Collection: pathwayCommons.cell-map

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null TNF alpha/NF-kB View Gene Set 0.0009552 170 0.009552 1 CELL_MAP - TNF alpha/NF-kB gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.humancyc

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null pyrimidine deoxyribonucleotides de novo biosynthesis View Gene Set 0.0001349 14 0.03506 1 HUMANCYC - pyrimidine deoxyribonucleotides de novo biosynthesis gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.nci-nature

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Aurora B signaling View Gene Set 5.124e-08 41 9.53e-06 1 NCI_NATURE - Aurora B signaling gene set www.pathwaycomm...
Null Validated targets of C-MYC transcriptional activation View Gene Set 1.534e-05 80 0.001426 2 NCI_NATURE - Validated targets of C-MYC transcriptional activation gene set www.pathwaycomm...
Null Signaling by Aurora kinases View Gene Set 2.925e-05 98 0.001814 3 NCI_NATURE - Signaling by Aurora kinases gene set www.pathwaycomm...
Null PLK1 signaling events View Gene Set 5.378e-05 104 0.002501 4 NCI_NATURE - PLK1 signaling events gene set www.pathwaycomm...
Null Polo-like kinase signaling events in the cell cycle View Gene Set 0.0001617 109 0.006014 5 NCI_NATURE - Polo-like kinase signaling events in the cell cycle gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.reactome

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Cell Cycle Mitotic View Gene Set 1.065e-40 312 1.189e-37 1 REACTOME - Cell Cycle Mitotic gene set www.pathwaycomm... Mitotic&format=...
Null DNA Replication View Gene Set 1.344e-31 200 7.508e-29 2 REACTOME - DNA Replication gene set www.pathwaycomm...
Null Mitotic M-M/G1 phases View Gene Set 3.746e-30 180 1.395e-27 3 REACTOME - Mitotic M-M/G1 phases gene set www.pathwaycomm...
Null Gene Expression View Gene Set 9.43e-25 381 2.633e-22 4 REACTOME - Gene Expression gene set www.pathwaycomm...
Null mRNA Processing View Gene Set 6.987e-24 158 1.561e-21 5 REACTOME - mRNA Processing gene set www.pathwaycomm...
Null Processing of Capped Intron-Containing Pre-mRNA View Gene Set 1.084e-23 138 2.018e-21 6 REACTOME - Processing of Capped Intron-Containing Pre-mRNA gene set www.pathwaycomm...
Null M Phase View Gene Set 9.985e-23 90 1.593e-20 7 REACTOME - M Phase gene set www.pathwaycomm...
Null Formation and Maturation of mRNA Transcript View Gene Set 2.432e-22 185 3.396e-20 8 REACTOME - Formation and Maturation of mRNA Transcript gene set www.pathwaycomm...
Null Mitotic Prometaphase View Gene Set 3.894e-21 86 4.833e-19 9 REACTOME - Mitotic Prometaphase gene set www.pathwaycomm...
Null mRNA Splicing - Major Pathway View Gene Set 2.246e-19 107 2.281e-17 10 REACTOME - mRNA Splicing - Major Pathway gene set www.pathwaycomm...
Null mRNA Splicing View Gene Set 2.246e-19 107 2.281e-17 10 REACTOME - mRNA Splicing gene set www.pathwaycomm...
Null Metabolism of RNA View Gene Set 4.347e-17 174 4.046e-15 12 REACTOME - Metabolism of RNA gene set www.pathwaycomm...
Null Cell Cycle Checkpoints View Gene Set 1.33e-16 124 1.143e-14 13 REACTOME - Cell Cycle Checkpoints gene set www.pathwaycomm...
Null Transport of Mature Transcript to Cytoplasm View Gene Set 2.985e-12 55 2.381e-10 14 REACTOME - Transport of Mature Transcript to Cytoplasm gene set www.pathwaycomm...
Null HIV Infection View Gene Set 3.734e-12 194 2.781e-10 15 REACTOME - HIV Infection gene set www.pathwaycomm...
Null G2/M Checkpoints View Gene Set 6.388e-12 43 4.197e-10 16 REACTOME - G2/M Checkpoints gene set www.pathwaycomm...
Null G2/M Transition View Gene Set 6.38e-12 96 4.197e-10 16 REACTOME - G2/M Transition gene set www.pathwaycomm...
Null Mitotic G2-G2/M phases View Gene Set 7.938e-12 98 4.926e-10 18 REACTOME - Mitotic G2-G2/M phases gene set www.pathwaycomm...
Null Centrosome maturation View Gene Set 1.722e-11 73 9.619e-10 19 REACTOME - Centrosome maturation gene set www.pathwaycomm...
Null Recruitment of mitotic centrosome proteins and complexes View Gene Set 1.722e-11 72 9.619e-10 19 REACTOME - Recruitment of mitotic centrosome proteins and complexes gene set www.pathwaycomm...
Null S Phase View Gene Set 2.712e-11 113 1.443e-09 21 REACTOME - S Phase gene set www.pathwaycomm...
Null G1/S Transition View Gene Set 2.932e-11 104 1.489e-09 22 REACTOME - G1/S Transition gene set www.pathwaycomm...
Null Transport of Mature mRNA derived from an Intron-Containing Transcript View Gene Set 5.365e-11 51 2.605e-09 23 REACTOME - Transport of Mature mRNA derived from an Intron-Containing Transcript gene set www.pathwaycomm...
Null Synthesis of DNA View Gene Set 6.75e-11 102 3.142e-09 24 REACTOME - Synthesis of DNA gene set www.pathwaycomm...
Null Regulation of mitotic cell cycle View Gene Set 7.851e-11 95 3.373e-09 25 REACTOME - Regulation of mitotic cell cycle gene set www.pathwaycomm...
Null APC/C-mediated degradation of cell cycle proteins View Gene Set 7.851e-11 95 3.373e-09 25 REACTOME - APC/C-mediated degradation of cell cycle proteins gene set www.pathwaycomm...
Null DNA Repair View Gene Set 8.638e-11 108 3.574e-09 27 REACTOME - DNA Repair gene set www.pathwaycomm...
Null Mitotic G1-G1/S phases View Gene Set 9.344e-11 113 3.727e-09 28 REACTOME - Mitotic G1-G1/S phases gene set www.pathwaycomm...
Null DNA Replication Pre-Initiation View Gene Set 1.245e-10 90 4.635e-09 29 REACTOME - DNA Replication Pre-Initiation gene set www.pathwaycomm...
Null M/G1 Transition View Gene Set 1.245e-10 90 4.635e-09 29 REACTOME - M/G1 Transition gene set www.pathwaycomm...
Null Activation of ATR in response to replication stress View Gene Set 1.432e-10 37 5.16e-09 31 REACTOME - Activation of ATR in response to replication stress gene set www.pathwaycomm...
Null Assembly of the pre-replicative complex View Gene Set 1.618e-10 75 5.648e-09 32 REACTOME - Assembly of the pre-replicative complex gene set www.pathwaycomm...
Null Host Interactions of HIV factors View Gene Set 2.402e-10 132 7.892e-09 33 REACTOME - Host Interactions of HIV factors gene set www.pathwaycomm...
Null Metabolism of mRNA View Gene Set 2.398e-10 125 7.892e-09 33 REACTOME - Metabolism of mRNA gene set www.pathwaycomm...
Null Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 4.023e-10 86 1.284e-08 35 REACTOME - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 View Gene Set 5.967e-10 77 1.851e-08 36 REACTOME - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 gene set www.pathwaycomm...
Null Regulation of DNA replication View Gene Set 1.058e-09 81 3.194e-08 37 REACTOME - Regulation of DNA replication gene set www.pathwaycomm...
Null Post-Elongation Processing of the Transcript View Gene Set 1.521e-09 43 4.143e-08 38 REACTOME - Post-Elongation Processing of the Transcript gene set www.pathwaycomm...
Null Cleavage of Growing Transcript in the Termination Region View Gene Set 1.521e-09 43 4.143e-08 38 REACTOME - Cleavage of Growing Transcript in the Termination Region gene set www.pathwaycomm...
Null RNA Polymerase II Transcription Termination View Gene Set 1.521e-09 43 4.143e-08 38 REACTOME - RNA Polymerase II Transcription Termination gene set www.pathwaycomm...
Null CDT1 association with the CDC6:ORC:origin complex View Gene Set 1.454e-09 66 4.143e-08 38 REACTOME - CDT1 association with the CDC6:ORC:origin complex gene set www.pathwaycomm...
Null Removal of licensing factors from origins View Gene Set 1.695e-09 78 4.507e-08 42 REACTOME - Removal of licensing factors from origins gene set www.pathwaycomm...
Null Regulation of APC/C activators between G1/S and early anaphase View Gene Set 2.579e-09 88 6.699e-08 43 REACTOME - Regulation of APC/C activators between G1/S and early anaphase gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 3.524e-09 77 8.946e-08 44 REACTOME - APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null Switching of origins to a post-replicative state View Gene Set 6.747e-09 76 1.614e-07 45 REACTOME - Switching of origins to a post-replicative state gene set www.pathwaycomm...
Null Orc1 removal from chromatin View Gene Set 6.747e-09 76 1.614e-07 45 REACTOME - Orc1 removal from chromatin gene set www.pathwaycomm...
Null snRNP Assembly View Gene Set 6.938e-09 50 1.614e-07 45 REACTOME - snRNP Assembly gene set www.pathwaycomm...
Null Metabolism of non-coding RNA View Gene Set 6.938e-09 50 1.614e-07 45 REACTOME - Metabolism of non-coding RNA gene set www.pathwaycomm...
Null RNA Polymerase II Transcription View Gene Set 8.751e-09 101 1.995e-07 49 REACTOME - RNA Polymerase II Transcription gene set www.pathwaycomm...
Null Post-Elongation Processing of Intron-Containing pre-mRNA View Gene Set 1.009e-08 34 2.209e-07 50 REACTOME - Post-Elongation Processing of Intron-Containing pre-mRNA gene set www.pathwaycomm...
Null mRNA 3'-end processing View Gene Set 1.009e-08 34 2.209e-07 50 REACTOME - mRNA 3'-end processing gene set www.pathwaycomm...
Null Cdc20:Phospho-APC/C mediated degradation of Cyclin A View Gene Set 1.775e-08 75 3.812e-07 52 REACTOME - Cdc20:Phospho-APC/C mediated degradation of Cyclin A gene set www.pathwaycomm...
Null Chromosome Maintenance View Gene Set 3.134e-08 69 6.604e-07 53 REACTOME - Chromosome Maintenance gene set www.pathwaycomm...
Null p53-Independent G1/S DNA damage checkpoint View Gene Set 3.863e-08 62 7.706e-07 54 REACTOME - p53-Independent G1/S DNA damage checkpoint gene set www.pathwaycomm...
Null p53-Independent DNA Damage Response View Gene Set 3.863e-08 62 7.706e-07 54 REACTOME - p53-Independent DNA Damage Response gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of Securin View Gene Set 3.852e-08 72 7.706e-07 54 REACTOME - APC/C:Cdc20 mediated degradation of Securin gene set www.pathwaycomm...
Null Loss of proteins required for interphase microtubule organization from the centrosome View Gene Set 4.164e-08 62 8.02e-07 57 REACTOME - Loss of proteins required for interphase microtubule organization from the centrosome gene set www.pathwaycomm...
Null Loss of Nlp from mitotic centrosomes View Gene Set 4.164e-08 62 8.02e-07 57 REACTOME - Loss of Nlp from mitotic centrosomes gene set www.pathwaycomm...
Null G2/M DNA damage checkpoint View Gene Set 6.036e-08 29 1.143e-06 59 REACTOME - G2/M DNA damage checkpoint gene set www.pathwaycomm...
Null Interactions of Rev with host cellular proteins View Gene Set 8.042e-08 33 1.497e-06 60 REACTOME - Interactions of Rev with host cellular proteins gene set www.pathwaycomm...
Null Autodegradation of Cdh1 by Cdh1:APC/C View Gene Set 8.523e-08 67 1.536e-06 61 REACTOME - Autodegradation of Cdh1 by Cdh1:APC/C gene set www.pathwaycomm...
Null Regulation of mRNA Stability by Proteins that Bind AU-rich Elements View Gene Set 8.506e-08 95 1.536e-06 61 REACTOME - Regulation of mRNA Stability by Proteins that Bind AU-rich Elements gene set www.pathwaycomm...
Null SCF-beta-TrCP mediated degradation of Emi1 View Gene Set 9.338e-08 60 1.656e-06 63 REACTOME - SCF-beta-TrCP mediated degradation of Emi1 gene set www.pathwaycomm...
Null Ubiquitin Mediated Degradation of Phosphorylated Cdc25A View Gene Set 9.525e-08 61 1.662e-06 64 REACTOME - Ubiquitin Mediated Degradation of Phosphorylated Cdc25A gene set www.pathwaycomm...
Null Rev-mediated nuclear export of HIV-1 RNA View Gene Set 2.302e-07 32 3.955e-06 65 REACTOME - Rev-mediated nuclear export of HIV-1 RNA gene set www.pathwaycomm...
Null Regulation of activated PAK-2p34 by proteasome mediated degradation View Gene Set 2.996e-07 57 5.07e-06 66 REACTOME - Regulation of activated PAK-2p34 by proteasome mediated degradation gene set www.pathwaycomm...
Null SCF(Skp2)-mediated degradation of p27/p21 View Gene Set 3.661e-07 52 6.103e-06 67 REACTOME - SCF(Skp2)-mediated degradation of p27/p21 gene set www.pathwaycomm...
Null Vpu mediated degradation of CD4 View Gene Set 3.99e-07 57 6.554e-06 68 REACTOME - Vpu mediated degradation of CD4 gene set www.pathwaycomm...
Null mRNA Splicing - Minor Pathway View Gene Set 4.373e-07 42 7.08e-06 69 REACTOME - mRNA Splicing - Minor Pathway gene set www.pathwaycomm...
Null Nuclear import of Rev protein View Gene Set 4.872e-07 30 7.774e-06 70 REACTOME - Nuclear import of Rev protein gene set www.pathwaycomm...
Null Degradation of beta-catenin by the destruction complex View Gene Set 5.168e-07 56 8.017e-06 71 REACTOME - Degradation of beta-catenin by the destruction complex gene set www.pathwaycomm...
Null Signaling by Wnt View Gene Set 5.168e-07 56 8.017e-06 71 REACTOME - Signaling by Wnt gene set www.pathwaycomm...
Null HIV Life Cycle View Gene Set 5.364e-07 103 8.207e-06 73 REACTOME - HIV Life Cycle gene set www.pathwaycomm...
Null Ubiquitin-dependent degradation of Cyclin D1 View Gene Set 5.741e-07 59 8.551e-06 74 REACTOME - Ubiquitin-dependent degradation of Cyclin D1 gene set www.pathwaycomm...
Null Ubiquitin-dependent degradation of Cyclin D View Gene Set 5.741e-07 59 8.551e-06 74 REACTOME - Ubiquitin-dependent degradation of Cyclin D gene set www.pathwaycomm...
Null Autodegradation of the E3 ubiquitin ligase COP1 View Gene Set 6.406e-07 60 9.416e-06 76 REACTOME - Autodegradation of the E3 ubiquitin ligase COP1 gene set www.pathwaycomm...
Null Transport of Mature mRNAs Derived from Intronless Transcripts View Gene Set 6.586e-07 36 9.553e-06 77 REACTOME - Transport of Mature mRNAs Derived from Intronless Transcripts gene set www.pathwaycomm...
Null G1/S DNA Damage Checkpoints View Gene Set 6.723e-07 68 9.628e-06 78 REACTOME - G1/S DNA Damage Checkpoints gene set www.pathwaycomm...
Null Vif-mediated degradation of APOBEC3G View Gene Set 7.008e-07 61 9.909e-06 79 REACTOME - Vif-mediated degradation of APOBEC3G gene set www.pathwaycomm...
Null CDK-mediated phosphorylation and removal of Cdc6 View Gene Set 7.564e-07 58 1.056e-05 80 REACTOME - CDK-mediated phosphorylation and removal of Cdc6 gene set www.pathwaycomm...
Null Transport of Mature mRNA Derived from an Intronless Transcript View Gene Set 7.82e-07 35 1.078e-05 81 REACTOME - Transport of Mature mRNA Derived from an Intronless Transcript gene set www.pathwaycomm...
Null Late Phase of HIV Life Cycle View Gene Set 9.879e-07 92 1.346e-05 82 REACTOME - Late Phase of HIV Life Cycle gene set www.pathwaycomm...
Null Stabilization of p53 View Gene Set 1.103e-06 61 1.485e-05 83 REACTOME - Stabilization of p53 gene set www.pathwaycomm...
Null Regulation of ornithine decarboxylase (ODC) View Gene Set 1.519e-06 62 2.02e-05 84 REACTOME - Regulation of ornithine decarboxylase (ODC) gene set www.pathwaycomm...
Null NEP/NS2 Interacts with the Cellular Export Machinery View Gene Set 1.583e-06 29 2.056e-05 85 REACTOME - NEP/NS2 Interacts with the Cellular Export Machinery gene set www.pathwaycomm...
Null Destabilization of mRNA by AUF1 (hnRNP D0) View Gene Set 1.579e-06 63 2.056e-05 85 REACTOME - Destabilization of mRNA by AUF1 (hnRNP D0) gene set www.pathwaycomm...
Null Transcription View Gene Set 1.844e-06 178 2.368e-05 87 REACTOME - Transcription gene set www.pathwaycomm...
Null Deadenylation-dependent mRNA decay View Gene Set 2.267e-06 46 2.878e-05 88 REACTOME - Deadenylation-dependent mRNA decay gene set www.pathwaycomm...
Null Cyclin A:Cdk2-associated events at S phase entry View Gene Set 2.44e-06 62 3.062e-05 89 REACTOME - Cyclin A:Cdk2-associated events at S phase entry gene set www.pathwaycomm...
Null Transport of Ribonucleoproteins into the Host Nucleus View Gene Set 3.006e-06 29 3.69e-05 90 REACTOME - Transport of Ribonucleoproteins into the Host Nucleus gene set www.pathwaycomm...
Null Export of Viral Ribonucleoproteins from Nucleus View Gene Set 2.983e-06 31 3.69e-05 90 REACTOME - Export of Viral Ribonucleoproteins from Nucleus gene set www.pathwaycomm...
Null Regulation of Apoptosis View Gene Set 3.552e-06 66 4.312e-05 92 REACTOME - Regulation of Apoptosis gene set www.pathwaycomm...
Null p53-Dependent G1/S DNA damage checkpoint View Gene Set 5.434e-06 64 6.457e-05 93 REACTOME - p53-Dependent G1/S DNA damage checkpoint gene set www.pathwaycomm...
Null p53-Dependent G1 DNA Damage Response View Gene Set 5.434e-06 64 6.457e-05 93 REACTOME - p53-Dependent G1 DNA Damage Response gene set www.pathwaycomm...
Null Fanconi Anemia pathway View Gene Set 7.479e-06 22 8.775e-05 95 REACTOME - Fanconi Anemia pathway gene set www.pathwaycomm...
Null Recruitment of NuMA to mitotic centrosomes View Gene Set 7.542e-06 14 8.775e-05 95 REACTOME - Recruitment of NuMA to mitotic centrosomes gene set www.pathwaycomm...
Null Transport of the SLBP Dependant Mature mRNA View Gene Set 8.623e-06 33 9.829e-05 97 REACTOME - Transport of the SLBP Dependant Mature mRNA gene set www.pathwaycomm...
Null tRNA Aminoacylation View Gene Set 8.587e-06 42 9.829e-05 97 REACTOME - tRNA Aminoacylation gene set www.pathwaycomm...
Null Transport of the SLBP independent Mature mRNA View Gene Set 1.037e-05 32 0.000117 99 REACTOME - Transport of the SLBP independent Mature mRNA gene set www.pathwaycomm...
Null Kinesins View Gene Set 1.06e-05 22 0.0001184 100 REACTOME - Kinesins gene set www.pathwaycomm...
Null Interactions of Vpr with host cellular proteins View Gene Set 1.273e-05 34 0.0001408 101 REACTOME - Interactions of Vpr with host cellular proteins gene set www.pathwaycomm...
Null Transcription-coupled NER (TC-NER) View Gene Set 1.302e-05 45 0.0001425 102 REACTOME - Transcription-coupled NER (TC-NER) gene set www.pathwaycomm...
Null Regulation of Glucokinase by Glucokinase Regulatory Protein View Gene Set 1.388e-05 29 0.0001505 103 REACTOME - Regulation of Glucokinase by Glucokinase Regulatory Protein gene set www.pathwaycomm...
Null Cyclin E associated events during G1/S transition View Gene Set 1.489e-05 64 0.0001599 104 REACTOME - Cyclin E associated events during G1/S transition gene set www.pathwaycomm...
Null Mitochondrial tRNA aminoacylation View Gene Set 1.528e-05 21 0.0001626 105 REACTOME - Mitochondrial tRNA aminoacylation gene set www.pathwaycomm...
Null Nucleotide Excision Repair View Gene Set 3.593e-05 51 0.0003786 106 REACTOME - Nucleotide Excision Repair gene set www.pathwaycomm...
Null Vpr-mediated nuclear import of PICs View Gene Set 4.081e-05 31 0.000426 107 REACTOME - Vpr-mediated nuclear import of PICs gene set www.pathwaycomm...
Null Influenza Infection View Gene Set 4.644e-05 143 0.0004803 108 REACTOME - Influenza Infection gene set www.pathwaycomm...
Null Deposition of New CENPA-containing Nucleosomes at the Centromere View Gene Set 6.495e-05 35 0.0006595 109 REACTOME - Deposition of New CENPA-containing Nucleosomes at the Centromere gene set www.pathwaycomm...
Null Nucleosome assembly View Gene Set 6.495e-05 35 0.0006595 109 REACTOME - Nucleosome assembly gene set www.pathwaycomm...
Null Pyrimidine biosynthesis View Gene Set 6.885e-05 6 0.0006929 111 REACTOME - Pyrimidine biosynthesis gene set www.pathwaycomm...
Null DNA strand elongation View Gene Set 7.52e-05 31 0.00075 112 REACTOME - DNA strand elongation gene set www.pathwaycomm...
Null Association of licensing factors with the pre-replicative complex View Gene Set 8.547e-05 15 0.0008449 113 REACTOME - Association of licensing factors with the pre-replicative complex gene set www.pathwaycomm...
Null Activation of the pre-replicative complex View Gene Set 0.0001002 30 0.0009815 114 REACTOME - Activation of the pre-replicative complex gene set www.pathwaycomm...
Null Glucose transport View Gene Set 0.0001157 38 0.001123 115 REACTOME - Glucose transport gene set www.pathwaycomm...
Null Hexose transport View Gene Set 0.0001249 40 0.001202 116 REACTOME - Hexose transport gene set www.pathwaycomm...
Null Apoptosis View Gene Set 0.0001371 148 0.001309 117 REACTOME - Apoptosis gene set www.pathwaycomm...
Null E2F-enabled inhibition of pre-replication complex formation View Gene Set 0.0001412 10 0.001337 118 REACTOME - E2F-enabled inhibition of pre-replication complex formation gene set www.pathwaycomm...
Null mRNA Decay by 3' to 5' Exoribonuclease View Gene Set 0.0001474 11 0.001384 119 REACTOME - mRNA Decay by 3' to 5' Exoribonuclease gene set www.pathwaycomm...
Null Activation of DNA fragmentation factor View Gene Set 0.0001654 8 0.001527 120 REACTOME - Activation of DNA fragmentation factor gene set www.pathwaycomm...
Null Apoptosis induced DNA fragmentation View Gene Set 0.0001654 8 0.001527 120 REACTOME - Apoptosis induced DNA fragmentation gene set www.pathwaycomm...
Null Homologous Recombination Repair View Gene Set 0.000197 22 0.001789 122 REACTOME - Homologous Recombination Repair gene set www.pathwaycomm...
Null Homologous recombination repair of replication-independent double-strand breaks View Gene Set 0.000197 22 0.001789 122 REACTOME - Homologous recombination repair of replication-independent double-strand breaks gene set www.pathwaycomm...
Null Metabolism of folate and pterines View Gene Set 0.0002134 8 0.001922 124 REACTOME - Metabolism of folate and pterines gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of Cyclin B View Gene Set 0.000222 22 0.001984 125 REACTOME - APC/C:Cdc20 mediated degradation of Cyclin B gene set www.pathwaycomm...
Null Double-Strand Break Repair View Gene Set 0.0002435 27 0.002158 126 REACTOME - Double-Strand Break Repair gene set www.pathwaycomm...
Null Influenza Life Cycle View Gene Set 0.0002701 138 0.002375 127 REACTOME - Influenza Life Cycle gene set www.pathwaycomm...
Null Extension of Telomeres View Gene Set 0.0002931 28 0.002558 128 REACTOME - Extension of Telomeres gene set www.pathwaycomm...
Null Metabolism of carbohydrates View Gene Set 0.0003198 93 0.002769 129 REACTOME - Metabolism of carbohydrates gene set www.pathwaycomm...
Null E2F mediated regulation of DNA replication View Gene Set 0.000387 28 0.003326 130 REACTOME - E2F mediated regulation of DNA replication gene set www.pathwaycomm...
Null G1/S-Specific Transcription View Gene Set 0.000482 16 0.00411 131 REACTOME - G1/S-Specific Transcription gene set www.pathwaycomm...
Null APC-Cdc20 mediated degradation of Nek2A View Gene Set 0.0005194 23 0.004396 132 REACTOME - APC-Cdc20 mediated degradation of Nek2A gene set www.pathwaycomm...
Null Cyclin B2 mediated events View Gene Set 0.0006015 5 0.005052 133 REACTOME - Cyclin B2 mediated events gene set www.pathwaycomm...
Null Telomere Maintenance View Gene Set 0.0006162 49 0.005099 134 REACTOME - Telomere Maintenance gene set www.pathwaycomm...
Null Protein folding View Gene Set 0.0006119 29 0.005099 134 REACTOME - Protein folding gene set www.pathwaycomm...
Null CDC6 association with the ORC:origin complex View Gene Set 0.0006225 11 0.005113 136 REACTOME - CDC6 association with the ORC:origin complex gene set www.pathwaycomm...
Null Citric acid cycle (TCA cycle) View Gene Set 0.0006453 19 0.005224 137 REACTOME - Citric acid cycle (TCA cycle) gene set www.pathwaycomm...
Null Phosphorylation of the APC/C View Gene Set 0.0006445 26 0.005224 137 REACTOME - Phosphorylation of the APC/C gene set www.pathwaycomm...
Null Translation View Gene Set 0.0006553 120 0.005266 139 REACTOME - Translation gene set www.pathwaycomm...
Null Unwinding of DNA View Gene Set 0.0006963 11 0.005556 140 REACTOME - Unwinding of DNA gene set www.pathwaycomm...
Null Post-Elongation Processing of Intronless pre-mRNA View Gene Set 0.0007147 23 0.005587 141 REACTOME - Post-Elongation Processing of Intronless pre-mRNA gene set www.pathwaycomm...
Null Processing of Capped Intronless Pre-mRNA View Gene Set 0.0007147 23 0.005587 141 REACTOME - Processing of Capped Intronless Pre-mRNA gene set www.pathwaycomm...
Null Pyruvate metabolism and Citric Acid (TCA) cycle View Gene Set 0.0007153 31 0.005587 141 REACTOME - Pyruvate metabolism and Citric Acid (TCA) cycle gene set www.pathwaycomm...
Null Metabolism of nucleotides View Gene Set 0.0007645 66 0.00593 144 REACTOME - Metabolism of nucleotides gene set www.pathwaycomm...
Null Respiratory electron transport ATP synthesis by chemiosmotic coupling and heat production by uncoupling proteins. View Gene Set 0.0007846 91 0.006044 145 REACTOME - Respiratory electron transport ATP synthesis by chemiosmotic coupling and heat production by uncoupling proteins. gene set www.pathwaycomm... ATP synthesis b... and heat produc...
Null Phosphorylation of Emi1 View Gene Set 0.000902 12 0.006901 146 REACTOME - Phosphorylation of Emi1 gene set www.pathwaycomm...
Null Formation of the HIV-1 Early Elongation Complex View Gene Set 0.0009201 32 0.006944 147 REACTOME - Formation of the HIV-1 Early Elongation Complex gene set www.pathwaycomm...
Null Formation of the Early Elongation Complex View Gene Set 0.0009201 32 0.006944 147 REACTOME - Formation of the Early Elongation Complex gene set www.pathwaycomm...
Null Gap-filling DNA repair synthesis and ligation in TC-NER View Gene Set 0.0009765 16 0.007271 149 REACTOME - Gap-filling DNA repair synthesis and ligation in TC-NER gene set www.pathwaycomm...
Null Gap-filling DNA repair synthesis and ligation in GG-NER View Gene Set 0.0009765 16 0.007271 149 REACTOME - Gap-filling DNA repair synthesis and ligation in GG-NER gene set www.pathwaycomm...
Null Recycling of eIF2:GDP View Gene Set 0.001137 8 0.00841 151 REACTOME - Recycling of eIF2:GDP gene set www.pathwaycomm...
Null Cap-dependent Translation Initiation View Gene Set 0.001158 113 0.008457 152 REACTOME - Cap-dependent Translation Initiation gene set www.pathwaycomm...
Null Eukaryotic Translation Initiation View Gene Set 0.001158 113 0.008457 152 REACTOME - Eukaryotic Translation Initiation gene set www.pathwaycomm...
Null Formation of HIV-1 elongation complex containing HIV-1 Tat View Gene Set 0.001211 41 0.00867 154 REACTOME - Formation of HIV-1 elongation complex containing HIV-1 Tat gene set www.pathwaycomm...
Null Tat-mediated elongation of the HIV-1 transcript View Gene Set 0.001211 41 0.00867 154 REACTOME - Tat-mediated elongation of the HIV-1 transcript gene set www.pathwaycomm...
Null HIV-1 Transcription Elongation View Gene Set 0.001211 41 0.00867 154 REACTOME - HIV-1 Transcription Elongation gene set www.pathwaycomm...
Null Telomere Extension By Telomerase View Gene Set 0.001229 6 0.008741 157 REACTOME - Telomere Extension By Telomerase gene set www.pathwaycomm...
Null Regulation of the Fanconi anemia pathway View Gene Set 0.001326 8 0.009372 158 REACTOME - Regulation of the Fanconi anemia pathway gene set www.pathwaycomm...
Null Ribosomal scanning and start codon recognition View Gene Set 0.001504 56 0.01057 159 REACTOME - Ribosomal scanning and start codon recognition gene set www.pathwaycomm...
Null Formation of transcription-coupled NER (TC-NER) repair complex View Gene Set 0.001676 29 0.01163 160 REACTOME - Formation of transcription-coupled NER (TC-NER) repair complex gene set www.pathwaycomm...
Null Dual incision reaction in TC-NER View Gene Set 0.001676 29 0.01163 160 REACTOME - Dual incision reaction in TC-NER gene set www.pathwaycomm...
Null Formation of HIV-1 elongation complex in the absence of HIV-1 Tat View Gene Set 0.001869 42 0.01273 162 REACTOME - Formation of HIV-1 elongation complex in the absence of HIV-1 Tat gene set www.pathwaycomm...
Null Formation of RNA Pol II elongation complex View Gene Set 0.001869 42 0.01273 162 REACTOME - Formation of RNA Pol II elongation complex gene set www.pathwaycomm...
Null RNA Polymerase II Transcription Elongation View Gene Set 0.001869 42 0.01273 162 REACTOME - RNA Polymerase II Transcription Elongation gene set www.pathwaycomm...
Null Global Genomic NER (GG-NER) View Gene Set 0.001955 35 0.01324 165 REACTOME - Global Genomic NER (GG-NER) gene set www.pathwaycomm...
Null Purine metabolism View Gene Set 0.002112 24 0.01421 166 REACTOME - Purine metabolism gene set www.pathwaycomm...
Null Destabilization of mRNA by KSRP View Gene Set 0.002153 18 0.0144 167 REACTOME - Destabilization of mRNA by KSRP gene set www.pathwaycomm...
Null Pentose phosphate pathway (hexose monophosphate shunt) View Gene Set 0.002463 6 0.01638 168 REACTOME - Pentose phosphate pathway (hexose monophosphate shunt) gene set www.pathwaycomm...
Null Deadenylation of mRNA View Gene Set 0.002645 22 0.01748 169 REACTOME - Deadenylation of mRNA gene set www.pathwaycomm...
Null Repair synthesis for gap-filling by DNA polymerase in TC-NER View Gene Set 0.003025 15 0.01976 170 REACTOME - Repair synthesis for gap-filling by DNA polymerase in TC-NER gene set www.pathwaycomm...
Null Repair synthesis of patch ~27-30 bases long by DNA polymerase View Gene Set 0.003025 15 0.01976 170 REACTOME - Repair synthesis of patch ~27-30 bases long by DNA polymerase gene set www.pathwaycomm...
Null Homologous DNA pairing and strand exchange View Gene Set 0.003102 7 0.02015 172 REACTOME - Homologous DNA pairing and strand exchange gene set www.pathwaycomm...
Null Activation of the mRNA upon binding of the cap-binding complex and eIFs and subsequent binding to 43S View Gene Set 0.003231 57 0.02086 173 REACTOME - Activation of the mRNA upon binding of the cap-binding complex and eIFs and subsequent binding to 43S gene set www.pathwaycomm... and subsequent ...
Null Processive synthesis on the C-strand of the telomere View Gene Set 0.003391 11 0.02165 174 REACTOME - Processive synthesis on the C-strand of the telomere gene set www.pathwaycomm...
Null S6K1-mediated signalling View Gene Set 0.003381 9 0.02165 174 REACTOME - S6K1-mediated signalling gene set www.pathwaycomm...
Null Host Interactions with Influenza Factors View Gene Set 0.003906 5 0.02479 176 REACTOME - Host Interactions with Influenza Factors gene set www.pathwaycomm...
Null Presynaptic phase of homologous DNA pairing and strand exchange View Gene Set 0.004242 6 0.02677 177 REACTOME - Presynaptic phase of homologous DNA pairing and strand exchange gene set www.pathwaycomm...
Null Translation initiation complex formation View Gene Set 0.004561 56 0.02862 178 REACTOME - Translation initiation complex formation gene set www.pathwaycomm...
Null mTORC1-mediated signalling View Gene Set 0.004606 11 0.02874 179 REACTOME - mTORC1-mediated signalling gene set www.pathwaycomm...
Null RNA Polymerase II Pre-transcription Events View Gene Set 0.004774 58 0.02962 180 REACTOME - RNA Polymerase II Pre-transcription Events gene set www.pathwaycomm...
Null Assembly of the ORC complex at the origin of replication View Gene Set 0.004912 6 0.03031 181 REACTOME - Assembly of the ORC complex at the origin of replication gene set www.pathwaycomm...
Null Respiratory electron transport View Gene Set 0.00497 76 0.03051 182 REACTOME - Respiratory electron transport gene set www.pathwaycomm...
Null GTP hydrolysis and joining of the 60S ribosomal subunit View Gene Set 0.005023 106 0.03066 183 REACTOME - GTP hydrolysis and joining of the 60S ribosomal subunit gene set www.pathwaycomm...
Null Pausing and recovery of Tat-mediated HIV-1 elongation View Gene Set 0.005253 29 0.03172 184 REACTOME - Pausing and recovery of Tat-mediated HIV-1 elongation gene set www.pathwaycomm...
Null Tat-mediated HIV-1 elongation arrest and recovery View Gene Set 0.005253 29 0.03172 184 REACTOME - Tat-mediated HIV-1 elongation arrest and recovery gene set www.pathwaycomm...
Null Mitotic Telophase /Cytokinesis View Gene Set 0.0053 10 0.03173 186 REACTOME - Mitotic Telophase /Cytokinesis gene set www.pathwaycomm...
Null Cyclin A/B1 associated events during G2/M transition View Gene Set 0.005312 19 0.03173 186 REACTOME - Cyclin A/B1 associated events during G2/M transition gene set www.pathwaycomm...
Null Methylation View Gene Set 0.005639 6 0.0335 188 REACTOME - Methylation gene set www.pathwaycomm...
Null Abortive elongation of HIV-1 transcript in the absence of Tat View Gene Set 0.00595 22 0.03516 189 REACTOME - Abortive elongation of HIV-1 transcript in the absence of Tat gene set www.pathwaycomm...
Null Cytosolic tRNA aminoacylation View Gene Set 0.005986 24 0.03519 190 REACTOME - Cytosolic tRNA aminoacylation gene set www.pathwaycomm...
Null 3' -UTR-mediated translational regulation View Gene Set 0.006655 105 0.03872 191 REACTOME - 3' -UTR-mediated translational regulation gene set www.pathwaycomm...
Null L13a-mediated translational silencing of Ceruloplasmin expression View Gene Set 0.006655 105 0.03872 191 REACTOME - L13a-mediated translational silencing of Ceruloplasmin expression gene set www.pathwaycomm...
Null S6K1 signalling View Gene Set 0.006937 5 0.04015 193 REACTOME - S6K1 signalling gene set www.pathwaycomm...
Null MicroRNA (miRNA) Biogenesis View Gene Set 0.007026 22 0.04025 194 REACTOME - MicroRNA (miRNA) Biogenesis gene set www.pathwaycomm...
Null Regulatory RNA pathways View Gene Set 0.007026 22 0.04025 194 REACTOME - Regulatory RNA pathways gene set www.pathwaycomm...
Null Processing of Intronless Pre-mRNAs View Gene Set 0.007311 14 0.04167 196 REACTOME - Processing of Intronless Pre-mRNAs gene set www.pathwaycomm...
Null Formation of the ternary complex and subsequently the 43S complex View Gene Set 0.007736 49 0.04386 197 REACTOME - Formation of the ternary complex and subsequently the 43S complex gene set www.pathwaycomm... and subsequentl... the 43S complex...
Null Pausing and recovery of elongation View Gene Set 0.008146 30 0.04517 198 REACTOME - Pausing and recovery of elongation gene set www.pathwaycomm...
Null Metabolism of amino acids and derivatives View Gene Set 0.008169 201 0.04517 198 REACTOME - Metabolism of amino acids and derivatives gene set www.pathwaycomm...
Null Elongation arrest and recovery View Gene Set 0.008146 30 0.04517 198 REACTOME - Elongation arrest and recovery gene set www.pathwaycomm...

Gene Set Collection: mirbase.targets

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-566 View Gene Set 2.154e-09 787 1.532e-06 1 microRNA targets for hsa-miR-566 from mirbase.targets www.mirbase.org...
Null hsa-miR-146b-3p View Gene Set 1.495e-07 695 5.315e-05 2 microRNA targets for hsa-miR-146b-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-941 View Gene Set 3.225e-06 590 0.0007643 3 microRNA targets for hsa-miR-941 from mirbase.targets www.mirbase.org...
Null hsa-miR-214 View Gene Set 2.33e-05 797 0.004142 4 microRNA targets for hsa-miR-214 from mirbase.targets www.mirbase.org...
Null hsa-miR-324-3p View Gene Set 3.761e-05 788 0.005348 5 microRNA targets for hsa-miR-324-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-611 View Gene Set 5.503e-05 671 0.005589 6 microRNA targets for hsa-miR-611 from mirbase.targets www.mirbase.org...
Null hsa-miR-874 View Gene Set 5.306e-05 722 0.005589 6 microRNA targets for hsa-miR-874 from mirbase.targets www.mirbase.org...
Null hsa-miR-486-3p View Gene Set 9.054e-05 773 0.006911 8 microRNA targets for hsa-miR-486-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-650 View Gene Set 9.72e-05 693 0.006911 8 microRNA targets for hsa-miR-650 from mirbase.targets www.mirbase.org...
Null hsa-miR-940 View Gene Set 8.559e-05 660 0.006911 8 microRNA targets for hsa-miR-940 from mirbase.targets www.mirbase.org...
Null hsa-miR-483-5p View Gene Set 0.0001112 717 0.00719 11 microRNA targets for hsa-miR-483-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-497 View Gene Set 0.0001299 805 0.007696 12 microRNA targets for hsa-miR-497 from mirbase.targets www.mirbase.org...
Null hsa-miR-323-5p View Gene Set 0.0001778 763 0.009568 13 microRNA targets for hsa-miR-323-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-552 View Gene Set 0.0001884 683 0.009568 13 microRNA targets for hsa-miR-552 from mirbase.targets www.mirbase.org...
Null hsa-let-7b View Gene Set 0.000237 775 0.01123 15 microRNA targets for hsa-let-7b from mirbase.targets www.mirbase.org...
Null hsa-let-7c View Gene Set 0.0002836 760 0.01253 16 microRNA targets for hsa-let-7c from mirbase.targets www.mirbase.org...
Null hsa-miR-99b View Gene Set 0.0002997 708 0.01253 16 microRNA targets for hsa-miR-99b from mirbase.targets www.mirbase.org...
Null hsa-miR-758 View Gene Set 0.0003445 660 0.01361 18 microRNA targets for hsa-miR-758 from mirbase.targets www.mirbase.org...
Null hsa-miR-602 View Gene Set 0.0003888 710 0.01455 19 microRNA targets for hsa-miR-602 from mirbase.targets www.mirbase.org...
Null hsa-miR-665 View Gene Set 0.0004234 617 0.01505 20 microRNA targets for hsa-miR-665 from mirbase.targets www.mirbase.org...
Null hsa-miR-604 View Gene Set 0.000598 691 0.01982 21 microRNA targets for hsa-miR-604 from mirbase.targets www.mirbase.org...
Null hsa-miR-886-3p View Gene Set 0.0006133 745 0.01982 21 microRNA targets for hsa-miR-886-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-518f View Gene Set 0.000674 948 0.02083 23 microRNA targets for hsa-miR-518f from mirbase.targets www.mirbase.org...
Null hsa-let-7g* View Gene Set 0.0007458 827 0.0221 24 microRNA targets for hsa-let-7g* from mirbase.targets www.mirbase.org...
Null hsa-miR-597 View Gene Set 0.0008613 645 0.0245 25 microRNA targets for hsa-miR-597 from mirbase.targets www.mirbase.org...
Null hsa-miR-331-3p View Gene Set 0.0009277 712 0.02537 26 microRNA targets for hsa-miR-331-3p from mirbase.targets www.mirbase.org...
Null hsa-let-7a View Gene Set 0.001342 808 0.03307 27 microRNA targets for hsa-let-7a from mirbase.targets www.mirbase.org...
Null hsa-miR-187 View Gene Set 0.001292 683 0.03307 27 microRNA targets for hsa-miR-187 from mirbase.targets www.mirbase.org...
Null hsa-miR-548d-3p View Gene Set 0.001349 978 0.03307 27 microRNA targets for hsa-miR-548d-3p from mirbase.targets www.mirbase.org...
Null hsa-let-7e View Gene Set 0.001534 778 0.03519 30 microRNA targets for hsa-let-7e from mirbase.targets www.mirbase.org...
Null hsa-let-7i View Gene Set 0.001502 808 0.03519 30 microRNA targets for hsa-let-7i from mirbase.targets www.mirbase.org...
Null hsa-miR-671-5p View Gene Set 0.001807 813 0.04014 32 microRNA targets for hsa-miR-671-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-523 View Gene Set 0.001927 655 0.04152 33 microRNA targets for hsa-miR-523 from mirbase.targets www.mirbase.org...
Null hsa-let-7d View Gene Set 0.002011 796 0.04206 34 microRNA targets for hsa-let-7d from mirbase.targets www.mirbase.org...
Null hsa-miR-107 View Gene Set 0.002542 725 0.04418 35 microRNA targets for hsa-miR-107 from mirbase.targets www.mirbase.org...
Null hsa-miR-186* View Gene Set 0.002589 485 0.04418 35 microRNA targets for hsa-miR-186* from mirbase.targets www.mirbase.org...
Null hsa-miR-329 View Gene Set 0.00239 652 0.04418 35 microRNA targets for hsa-miR-329 from mirbase.targets www.mirbase.org...
Null hsa-miR-512-3p View Gene Set 0.002443 697 0.04418 35 microRNA targets for hsa-miR-512-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-596 View Gene Set 0.00261 644 0.04418 35 microRNA targets for hsa-miR-596 from mirbase.targets www.mirbase.org...
Null hsa-miR-615-3p View Gene Set 0.002253 757 0.04418 35 microRNA targets for hsa-miR-615-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-661 View Gene Set 0.002207 575 0.04418 35 microRNA targets for hsa-miR-661 from mirbase.targets www.mirbase.org...
Null hsa-miR-744 View Gene Set 0.002417 715 0.04418 35 microRNA targets for hsa-miR-744 from mirbase.targets www.mirbase.org...
Null hsa-miR-31 View Gene Set 0.002869 683 0.04637 43 microRNA targets for hsa-miR-31 from mirbase.targets www.mirbase.org...
Null hsa-miR-518a-3p View Gene Set 0.002834 925 0.04637 43 microRNA targets for hsa-miR-518a-3p from mirbase.targets www.mirbase.org...

Gene Set Collection: miRNAtargetUnion

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-566 View Gene Set 2.219e-06 1066 0.005134 1 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-566 from miRNAtargetUnion www.mirbase.org...