Results

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Go to: Gene Set Collection: KEGG
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Go to: Gene Set Collection: Broad.c2.CP.KEGG
Go to: Gene Set Collection: Broad.c2.CP.REACTOME
Go to: Gene Set Collection: Broad.c3.TFT
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Go to: Gene Set Collection: Broad.c4.CM
Go to: Gene Set Collection: Broad.c5.BP
Go to: Gene Set Collection: Broad.c5.CC
Go to: Gene Set Collection: Broad.c5.MF
Go to: Gene Set Collection: PMID
Go to: Gene Set Collection: ChromosomalTiles5Mb
Go to: Gene Set Collection: Prosite
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Go to: Gene Set Collection: ppi.BIND
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Go to: Gene Set Collection: ppi.anyDB
Go to: Gene Set Collection: pathwayCommons.cell-map
Go to: Gene Set Collection: pathwayCommons.nci-nature
Go to: Gene Set Collection: pathwayCommons.reactome
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Go to: Gene Set Collection: miRNAtargetUnion
Go to: Gene Set Collection: hprdBatch.UP
Go to: Gene Set Collection: hprdBatch.DIFFERENT
Go to: Gene Set Collection: hprdManual.UP

AFA results for: tVPAda2DU

Click on the heading for any column to sort by that column.

Gene Set Collection: KEGG

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
KEGG 03040 View Gene Set 1.215e-22 128 2.601e-20 1 Spliceosome www.genome.jp/d...
KEGG 04110 View Gene Set 2.883e-09 128 3.085e-07 2 Cell cycle www.genome.jp/d...
KEGG 03050 View Gene Set 1.585e-07 48 1.13e-05 3 Proteasome www.genome.jp/d...
KEGG 00240 View Gene Set 1.368e-06 99 6.762e-05 4 Pyrimidine metabolism www.genome.jp/d...
KEGG 03018 View Gene Set 1.58e-06 59 6.762e-05 4 RNA degradation www.genome.jp/d...
KEGG 03030 View Gene Set 2.28e-06 36 8.132e-05 6 DNA replication www.genome.jp/d...
KEGG 00970 View Gene Set 1.077e-05 41 0.0003292 7 Aminoacyl-tRNA biosynthesis www.genome.jp/d...
KEGG 03430 View Gene Set 5.145e-05 23 0.001223 8 Mismatch repair www.genome.jp/d...
KEGG 04740 View Gene Set 4.785e-05 388 0.001223 8 Olfactory transduction www.genome.jp/d...
KEGG 03440 View Gene Set 6.087e-05 28 0.001303 10 Homologous recombination www.genome.jp/d...
KEGG 03410 View Gene Set 8.025e-05 34 0.001561 11 Base excision repair www.genome.jp/d...
KEGG 03010 View Gene Set 0.0003302 88 0.005889 12 Ribosome www.genome.jp/d...
KEGG 00670 View Gene Set 0.0006498 17 0.0107 13 One carbon pool by folate www.genome.jp/d...
KEGG 03420 View Gene Set 0.002296 44 0.03509 14 Nucleotide excision repair www.genome.jp/d...

Gene Set Collection: GO

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
GO GO:0044428 View Gene Set 7.431e-88 1938 9.928e-84 1 nuclear part amigo.geneontol...
GO GO:0005634 View Gene Set 3.429e-76 5198 2.291e-72 2 nucleus amigo.geneontol...
GO GO:0031981 View Gene Set 1.18e-73 1518 5.253e-70 3 nuclear lumen amigo.geneontol...
GO GO:0070013 View Gene Set 7.162e-67 1845 2.392e-63 4 intracellular organelle lumen amigo.geneontol...
GO GO:0043233 View Gene Set 1.76e-64 1881 4.702e-61 5 organelle lumen amigo.geneontol...
GO GO:0031974 View Gene Set 5.065e-64 1917 1.049e-60 6 membrane-enclosed lumen amigo.geneontol...
GO GO:0003676 View Gene Set 5.499e-64 2979 1.049e-60 6 nucleic acid binding amigo.geneontol...
GO GO:0006396 View Gene Set 3.557e-63 578 5.941e-60 8 RNA processing amigo.geneontol...
GO GO:0090304 View Gene Set 3.786e-62 3724 5.62e-59 9 nucleic acid metabolic process amigo.geneontol...
GO GO:0006139 View Gene Set 1.92e-54 4294 2.565e-51 10 nucleobase nucleoside nucleotide and nucleic acid metabolic process amigo.geneontol...
GO GO:0003723 View Gene Set 1.385e-53 732 1.683e-50 11 RNA binding amigo.geneontol...
GO GO:0010467 View Gene Set 8.766e-53 3806 9.218e-50 12 gene expression amigo.geneontol...
GO GO:0034641 View Gene Set 8.97e-53 4584 9.218e-50 12 cellular nitrogen compound metabolic process amigo.geneontol...
GO GO:0006807 View Gene Set 9.008e-49 4698 8.596e-46 14 nitrogen compound metabolic process amigo.geneontol...
GO GO:0030529 View Gene Set 1.268e-48 504 1.129e-45 15 ribonucleoprotein complex amigo.geneontol...
GO GO:0044260 View Gene Set 2.481e-48 5699 2.071e-45 16 cellular macromolecule metabolic process amigo.geneontol...
GO GO:0016070 View Gene Set 2.127e-43 2596 1.671e-40 17 RNA metabolic process amigo.geneontol...
GO GO:0005730 View Gene Set 6.696e-43 734 4.97e-40 18 nucleolus amigo.geneontol...
GO GO:0008380 View Gene Set 7.829e-42 300 5.505e-39 19 RNA splicing amigo.geneontol...
GO GO:0005654 View Gene Set 8.485e-42 939 5.668e-39 20 nucleoplasm amigo.geneontol...
GO GO:0043170 View Gene Set 2.329e-40 6274 1.482e-37 21 macromolecule metabolic process amigo.geneontol...
GO GO:0016071 View Gene Set 3.903e-39 381 2.37e-36 22 mRNA metabolic process amigo.geneontol...
GO GO:0006397 View Gene Set 5.247e-35 317 2.943e-32 23 mRNA processing amigo.geneontol...
GO GO:0022613 View Gene Set 5.287e-35 194 2.943e-32 23 ribonucleoprotein complex biogenesis amigo.geneontol...
GO GO:0043228 View Gene Set 3.402e-34 2690 1.748e-31 25 non-membrane-bounded organelle amigo.geneontol...
GO GO:0043232 View Gene Set 3.402e-34 2690 1.748e-31 25 intracellular non-membrane-bounded organelle amigo.geneontol...
GO GO:0009059 View Gene Set 1.682e-31 3597 8.323e-29 27 macromolecule biosynthetic process amigo.geneontol...
GO GO:0034645 View Gene Set 6.214e-31 3529 2.965e-28 28 cellular macromolecule biosynthetic process amigo.geneontol...
GO GO:0005694 View Gene Set 4.078e-30 507 1.879e-27 29 chromosome amigo.geneontol...
GO GO:0044451 View Gene Set 1.555e-27 600 6.923e-25 30 nucleoplasm part amigo.geneontol...
GO GO:0034660 View Gene Set 1.111e-26 236 4.788e-24 31 ncRNA metabolic process amigo.geneontol...
GO GO:0042254 View Gene Set 2.162e-26 130 9.026e-24 32 ribosome biogenesis amigo.geneontol...
GO GO:0044249 View Gene Set 4.082e-26 4326 1.652e-23 33 cellular biosynthetic process amigo.geneontol...
GO GO:0032991 View Gene Set 9.556e-26 3237 3.755e-23 34 macromolecular complex amigo.geneontol...
GO GO:0009058 View Gene Set 2.683e-25 4436 1.024e-22 35 biosynthetic process amigo.geneontol...
GO GO:0044427 View Gene Set 3.415e-25 420 1.267e-22 36 chromosomal part amigo.geneontol...
GO GO:0022402 View Gene Set 1.869e-24 676 6.75e-22 37 cell cycle process amigo.geneontol...
GO GO:0005681 View Gene Set 2.912e-24 135 1.024e-21 38 spliceosomal complex amigo.geneontol...
GO GO:0044237 View Gene Set 4.385e-24 7431 1.502e-21 39 cellular metabolic process amigo.geneontol...
GO GO:0034470 View Gene Set 5.304e-24 193 1.771e-21 40 ncRNA processing amigo.geneontol...
GO GO:0044238 View Gene Set 5.918e-24 7629 1.928e-21 41 primary metabolic process amigo.geneontol...
GO GO:0000279 View Gene Set 2.358e-23 406 7.499e-21 42 M phase amigo.geneontol...
GO GO:0000775 View Gene Set 3.066e-22 146 9.526e-20 43 chromosome centromeric region amigo.geneontol...
GO GO:0007049 View Gene Set 5.871e-22 1006 1.783e-19 44 cell cycle amigo.geneontol...
GO GO:0000375 View Gene Set 8.368e-22 106 2.484e-19 45 RNA splicing via transesterification reactions amigo.geneontol...
GO GO:0000278 View Gene Set 9.613e-22 489 2.792e-19 46 mitotic cell cycle amigo.geneontol...
GO GO:0000793 View Gene Set 1.609e-21 136 4.573e-19 47 condensed chromosome amigo.geneontol...
GO GO:0022403 View Gene Set 2.587e-21 522 7.201e-19 48 cell cycle phase amigo.geneontol...
GO GO:0051276 View Gene Set 2.721e-21 548 7.42e-19 49 chromosome organization amigo.geneontol...
GO GO:0003677 View Gene Set 7.644e-21 2028 2.042e-18 50 DNA binding amigo.geneontol...
GO GO:0016072 View Gene Set 3.014e-20 101 7.896e-18 51 rRNA metabolic process amigo.geneontol...
GO GO:0006412 View Gene Set 3.076e-20 412 7.902e-18 52 translation amigo.geneontol...
GO GO:0000377 View Gene Set 1.135e-19 97 2.808e-17 53 RNA splicing via transesterification reactions with bulged adenosine as nucleophile amigo.geneontol...
GO GO:0000398 View Gene Set 1.135e-19 97 2.808e-17 53 nuclear mRNA splicing via spliceosome amigo.geneontol...
GO GO:0006364 View Gene Set 2.421e-19 97 5.88e-17 55 rRNA processing amigo.geneontol...
GO GO:0000087 View Gene Set 4.766e-19 286 1.137e-16 56 M phase of mitotic cell cycle amigo.geneontol...
GO GO:0000280 View Gene Set 6.374e-19 276 1.468e-16 57 nuclear division amigo.geneontol...
GO GO:0007067 View Gene Set 6.374e-19 276 1.468e-16 57 mitosis amigo.geneontol...
GO GO:0007059 View Gene Set 1.59e-18 94 3.6e-16 59 chromosome segregation amigo.geneontol...
GO GO:0048285 View Gene Set 1.687e-18 286 3.757e-16 60 organelle fission amigo.geneontol...
GO GO:0006259 View Gene Set 6.079e-18 592 1.331e-15 61 DNA metabolic process amigo.geneontol...
GO GO:0000776 View Gene Set 2.433e-17 92 5.242e-15 62 kinetochore amigo.geneontol...
GO GO:0043227 View Gene Set 4.225e-17 8383 8.961e-15 63 membrane-bounded organelle amigo.geneontol...
GO GO:0060255 View Gene Set 6.725e-17 3411 1.404e-14 64 regulation of macromolecule metabolic process amigo.geneontol...
GO GO:0043231 View Gene Set 7.166e-17 8376 1.473e-14 65 intracellular membrane-bounded organelle amigo.geneontol...
GO GO:0008152 View Gene Set 1.205e-16 8439 2.44e-14 66 metabolic process amigo.geneontol...
GO GO:0010556 View Gene Set 4.384e-16 2901 8.743e-14 67 regulation of macromolecule biosynthetic process amigo.geneontol...
GO GO:0016604 View Gene Set 5.233e-16 198 1.028e-13 68 nuclear body amigo.geneontol...
GO GO:0006350 View Gene Set 6.311e-16 2744 1.222e-13 69 transcription amigo.geneontol...
GO GO:0031326 View Gene Set 1.926e-15 3048 3.676e-13 70 regulation of cellular biosynthetic process amigo.geneontol...
GO GO:0010468 View Gene Set 2.902e-15 2958 5.461e-13 71 regulation of gene expression amigo.geneontol...
GO GO:0009889 View Gene Set 3.438e-15 3070 6.379e-13 72 regulation of biosynthetic process amigo.geneontol...
GO GO:0006260 View Gene Set 6.37e-15 239 1.166e-12 73 DNA replication amigo.geneontol...
GO GO:0000777 View Gene Set 8.275e-15 74 1.494e-12 74 condensed chromosome kinetochore amigo.geneontol...
GO GO:0050657 View Gene Set 9.114e-15 102 1.581e-12 75 nucleic acid transport amigo.geneontol...
GO GO:0050658 View Gene Set 9.114e-15 102 1.581e-12 75 RNA transport amigo.geneontol...
GO GO:0051236 View Gene Set 9.114e-15 102 1.581e-12 75 establishment of RNA localization amigo.geneontol...
GO GO:0044446 View Gene Set 1.509e-14 5019 2.585e-12 78 intracellular organelle part amigo.geneontol...
GO GO:0000779 View Gene Set 1.846e-14 79 3.122e-12 79 condensed chromosome centromeric region amigo.geneontol...
GO GO:0006403 View Gene Set 1.988e-14 104 3.32e-12 80 RNA localization amigo.geneontol...
GO GO:0015931 View Gene Set 2.31e-14 118 3.811e-12 81 nucleobase nucleoside nucleotide and nucleic acid transport amigo.geneontol...
GO GO:0005819 View Gene Set 3.662e-14 167 5.967e-12 82 spindle amigo.geneontol...
GO GO:0044422 View Gene Set 4.764e-14 5089 7.668e-12 83 organelle part amigo.geneontol...
GO GO:0043229 View Gene Set 6.358e-14 9346 1.011e-11 84 intracellular organelle amigo.geneontol...
GO GO:0000166 View Gene Set 6.646e-14 2257 1.045e-11 85 nucleotide binding amigo.geneontol...
GO GO:0005840 View Gene Set 7.745e-14 198 1.203e-11 86 ribosome amigo.geneontol...
GO GO:0080090 View Gene Set 9.477e-14 3585 1.455e-11 87 regulation of primary metabolic process amigo.geneontol...
GO GO:0043226 View Gene Set 1.15e-13 9360 1.746e-11 88 organelle amigo.geneontol...
GO GO:0022618 View Gene Set 1.461e-13 76 2.193e-11 89 ribonucleoprotein complex assembly amigo.geneontol...
GO GO:0000819 View Gene Set 2.731e-13 38 4.055e-11 90 sister chromatid segregation amigo.geneontol...
GO GO:0051171 View Gene Set 3.012e-13 3066 4.422e-11 91 regulation of nitrogen compound metabolic process amigo.geneontol...
GO GO:0019219 View Gene Set 4.272e-13 3040 6.204e-11 92 regulation of nucleobase nucleoside nucleotide and nucleic acid metabolic process amigo.geneontol...
GO GO:0006974 View Gene Set 4.391e-13 412 6.241e-11 93 response to DNA damage stimulus amigo.geneontol...
GO GO:0034621 View Gene Set 4.345e-13 458 6.241e-11 93 cellular macromolecular complex subunit organization amigo.geneontol...
GO GO:0000070 View Gene Set 5.601e-13 37 7.876e-11 95 mitotic sister chromatid segregation amigo.geneontol...
GO GO:0044085 View Gene Set 7.523e-13 1167 1.047e-10 96 cellular component biogenesis amigo.geneontol...
GO GO:0006281 View Gene Set 7.822e-13 309 1.074e-10 97 DNA repair amigo.geneontol...
GO GO:0034622 View Gene Set 7.878e-13 393 1.074e-10 97 cellular macromolecular complex assembly amigo.geneontol...
GO GO:0006996 View Gene Set 9.867e-13 1501 1.331e-10 99 organelle organization amigo.geneontol...
GO GO:0045449 View Gene Set 1.148e-12 2647 1.533e-10 100 regulation of transcription amigo.geneontol...
GO GO:0031323 View Gene Set 1.446e-12 3768 1.913e-10 101 regulation of cellular metabolic process amigo.geneontol...
GO GO:0007051 View Gene Set 1.625e-12 57 2.128e-10 102 spindle organization amigo.geneontol...
GO GO:0071103 View Gene Set 4.444e-12 140 5.764e-10 103 DNA conformation change amigo.geneontol...
GO GO:0051028 View Gene Set 5.407e-12 90 6.945e-10 104 mRNA transport amigo.geneontol...
GO GO:0051301 View Gene Set 6.197e-12 358 7.884e-10 105 cell division amigo.geneontol...
GO GO:0019222 View Gene Set 2.455e-11 4060 3.094e-09 106 regulation of metabolic process amigo.geneontol...
GO GO:0003735 View Gene Set 3.696e-11 158 4.615e-09 107 structural constituent of ribosome amigo.geneontol...
GO GO:0005524 View Gene Set 4.343e-11 1480 5.373e-09 108 ATP binding amigo.geneontol...
GO GO:0006325 View Gene Set 4.541e-11 425 5.566e-09 109 chromatin organization amigo.geneontol...
GO GO:0006399 View Gene Set 4.739e-11 118 5.756e-09 110 tRNA metabolic process amigo.geneontol...
GO GO:0032559 View Gene Set 9.16e-11 1503 1.103e-08 111 adenyl ribonucleotide binding amigo.geneontol...
GO GO:0031145 View Gene Set 9.376e-11 64 1.118e-08 112 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0033279 View Gene Set 1.005e-10 121 1.188e-08 113 ribosomal subunit amigo.geneontol...
GO GO:0030554 View Gene Set 1.62e-10 1584 1.898e-08 114 adenyl nucleotide binding amigo.geneontol...
GO GO:0051439 View Gene Set 1.68e-10 68 1.952e-08 115 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0000228 View Gene Set 1.992e-10 177 2.294e-08 116 nuclear chromosome amigo.geneontol...
GO GO:0016607 View Gene Set 2.857e-10 116 3.262e-08 117 nuclear speck amigo.geneontol...
GO GO:0051436 View Gene Set 3.763e-10 62 4.26e-08 118 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0005643 View Gene Set 5.642e-10 71 6.335e-08 119 nuclear pore amigo.geneontol...
GO GO:0008026 View Gene Set 6.59e-10 105 7.277e-08 120 ATP-dependent helicase activity amigo.geneontol...
GO GO:0070035 View Gene Set 6.59e-10 105 7.277e-08 120 purine NTP-dependent helicase activity amigo.geneontol...
GO GO:0051168 View Gene Set 7.305e-10 71 8e-08 122 nuclear export amigo.geneontol...
GO GO:0051352 View Gene Set 8.892e-10 66 9.581e-08 123 negative regulation of ligase activity amigo.geneontol...
GO GO:0051444 View Gene Set 8.892e-10 66 9.581e-08 123 negative regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0031397 View Gene Set 9.023e-10 78 9.644e-08 125 negative regulation of protein ubiquitination amigo.geneontol...
GO GO:0051437 View Gene Set 1.022e-09 64 1.083e-07 126 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0005488 View Gene Set 1.231e-09 12334 1.295e-07 127 binding amigo.geneontol...
GO GO:0006323 View Gene Set 1.354e-09 119 1.414e-07 128 DNA packaging amigo.geneontol...
GO GO:0046930 View Gene Set 1.553e-09 85 1.609e-07 129 pore complex amigo.geneontol...
GO GO:0006261 View Gene Set 1.832e-09 74 1.883e-07 130 DNA-dependent DNA replication amigo.geneontol...
GO GO:0008135 View Gene Set 1.882e-09 86 1.92e-07 131 translation factor activity nucleic acid binding amigo.geneontol...
GO GO:0003743 View Gene Set 2.052e-09 52 2.077e-07 132 translation initiation factor activity amigo.geneontol...
GO GO:0051340 View Gene Set 2.196e-09 85 2.206e-07 133 regulation of ligase activity amigo.geneontol...
GO GO:0051438 View Gene Set 2.431e-09 82 2.424e-07 134 regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0004386 View Gene Set 3.267e-09 144 3.233e-07 135 helicase activity amigo.geneontol...
GO GO:0044424 View Gene Set 3.608e-09 10976 3.545e-07 136 intracellular part amigo.geneontol...
GO GO:0000502 View Gene Set 3.894e-09 63 3.797e-07 137 proteasome complex amigo.geneontol...
GO GO:0000785 View Gene Set 4.115e-09 213 3.984e-07 138 chromatin amigo.geneontol...
GO GO:0051351 View Gene Set 4.163e-09 74 4.001e-07 139 positive regulation of ligase activity amigo.geneontol...
GO GO:0051443 View Gene Set 4.468e-09 71 4.264e-07 140 positive regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0000226 View Gene Set 5.735e-09 178 5.434e-07 141 microtubule cytoskeleton organization amigo.geneontol...
GO GO:0015030 View Gene Set 5.945e-09 43 5.594e-07 142 Cajal body amigo.geneontol...
GO GO:0001882 View Gene Set 7.071e-09 1630 6.606e-07 143 nucleoside binding amigo.geneontol...
GO GO:0000922 View Gene Set 1.017e-08 63 9.435e-07 144 spindle pole amigo.geneontol...
GO GO:0006405 View Gene Set 1.204e-08 44 1.109e-06 145 RNA export from nucleus amigo.geneontol...
GO GO:0065003 View Gene Set 1.257e-08 763 1.15e-06 146 macromolecular complex assembly amigo.geneontol...
GO GO:0001883 View Gene Set 1.301e-08 1620 1.183e-06 147 purine nucleoside binding amigo.geneontol...
GO GO:0006351 View Gene Set 1.712e-08 1949 1.545e-06 148 transcription DNA-dependent amigo.geneontol...
GO GO:0050000 View Gene Set 2.098e-08 17 1.869e-06 149 chromosome localization amigo.geneontol...
GO GO:0051303 View Gene Set 2.098e-08 17 1.869e-06 149 establishment of chromosome localization amigo.geneontol...
GO GO:0043933 View Gene Set 2.339e-08 836 2.069e-06 151 macromolecular complex subunit organization amigo.geneontol...
GO GO:0032774 View Gene Set 2.376e-08 1953 2.074e-06 152 RNA biosynthetic process amigo.geneontol...
GO GO:0000794 View Gene Set 2.37e-08 52 2.074e-06 152 condensed nuclear chromosome amigo.geneontol...
GO GO:0005876 View Gene Set 2.463e-08 35 2.137e-06 154 spindle microtubule amigo.geneontol...
GO GO:0016568 View Gene Set 2.527e-08 324 2.178e-06 155 chromatin modification amigo.geneontol...
GO GO:0003697 View Gene Set 2.635e-08 58 2.257e-06 156 single-stranded DNA binding amigo.geneontol...
GO GO:0044452 View Gene Set 2.913e-08 28 2.478e-06 157 nucleolar part amigo.geneontol...
GO GO:0030532 View Gene Set 4.34e-08 32 3.669e-06 158 small nuclear ribonucleoprotein complex amigo.geneontol...
GO GO:0000387 View Gene Set 8.8e-08 31 7.395e-06 159 spliceosomal snRNP assembly amigo.geneontol...
GO GO:0008033 View Gene Set 9.659e-08 78 8.065e-06 160 tRNA processing amigo.geneontol...
GO GO:0005622 View Gene Set 1.016e-07 11329 8.433e-06 161 intracellular amigo.geneontol...
GO GO:0051321 View Gene Set 1.567e-07 115 1.292e-05 162 meiotic cell cycle amigo.geneontol...
GO GO:0051310 View Gene Set 2.374e-07 13 1.946e-05 163 metaphase plate congression amigo.geneontol...
GO GO:0006401 View Gene Set 2.575e-07 74 2.096e-05 164 RNA catabolic process amigo.geneontol...
GO GO:0007126 View Gene Set 2.604e-07 113 2.096e-05 164 meiosis amigo.geneontol...
GO GO:0051327 View Gene Set 2.604e-07 113 2.096e-05 164 M phase of meiotic cell cycle amigo.geneontol...
GO GO:0004518 View Gene Set 2.772e-07 161 2.198e-05 167 nuclease activity amigo.geneontol...
GO GO:0032553 View Gene Set 2.781e-07 1851 2.198e-05 167 ribonucleotide binding amigo.geneontol...
GO GO:0032555 View Gene Set 2.781e-07 1851 2.198e-05 167 purine ribonucleotide binding amigo.geneontol...
GO GO:0000075 View Gene Set 2.956e-07 109 2.323e-05 170 cell cycle checkpoint amigo.geneontol...
GO GO:0043566 View Gene Set 3.176e-07 149 2.481e-05 171 structure-specific DNA binding amigo.geneontol...
GO GO:0016741 View Gene Set 3.442e-07 179 2.674e-05 172 transferase activity transferring one-carbon groups amigo.geneontol...
GO GO:0008168 View Gene Set 4.054e-07 176 3.131e-05 173 methyltransferase activity amigo.geneontol...
GO GO:0017076 View Gene Set 4.9e-07 1934 3.763e-05 174 purine nucleotide binding amigo.geneontol...
GO GO:0033554 View Gene Set 4.942e-07 698 3.773e-05 175 cellular response to stress amigo.geneontol...
GO GO:0006366 View Gene Set 6.26e-07 919 4.752e-05 176 transcription from RNA polymerase II promoter amigo.geneontol...
GO GO:0000184 View Gene Set 6.733e-07 30 5.082e-05 177 nuclear-transcribed mRNA catabolic process nonsense-mediated decay amigo.geneontol...
GO GO:0007606 View Gene Set 6.825e-07 478 5.123e-05 178 sensory perception of chemical stimulus amigo.geneontol...
GO GO:0005515 View Gene Set 6.959e-07 8146 5.194e-05 179 protein binding amigo.geneontol...
GO GO:0008408 View Gene Set 7.575e-07 27 5.623e-05 180 3'-5' exonuclease activity amigo.geneontol...
GO GO:0031396 View Gene Set 7.895e-07 121 5.827e-05 181 regulation of protein ubiquitination amigo.geneontol...
GO GO:0000313 View Gene Set 9.961e-07 49 7.272e-05 182 organellar ribosome amigo.geneontol...
GO GO:0005761 View Gene Set 9.961e-07 49 7.272e-05 182 mitochondrial ribosome amigo.geneontol...
GO GO:0044454 View Gene Set 1.059e-06 139 7.689e-05 184 nuclear chromosome part amigo.geneontol...
GO GO:0006413 View Gene Set 1.241e-06 62 8.962e-05 185 translational initiation amigo.geneontol...
GO GO:0004527 View Gene Set 1.345e-06 57 9.663e-05 186 exonuclease activity amigo.geneontol...
GO GO:0000940 View Gene Set 1.367e-06 12 9.767e-05 187 outer kinetochore of condensed chromosome amigo.geneontol...
GO GO:0006333 View Gene Set 1.378e-06 129 9.79e-05 188 chromatin assembly or disassembly amigo.geneontol...
GO GO:0003678 View Gene Set 1.412e-06 44 9.984e-05 189 DNA helicase activity amigo.geneontol...
GO GO:0006310 View Gene Set 1.425e-06 130 0.0001002 190 DNA recombination amigo.geneontol...
GO GO:0044265 View Gene Set 1.708e-06 479 0.0001194 191 cellular macromolecule catabolic process amigo.geneontol...
GO GO:0043234 View Gene Set 1.777e-06 2680 0.0001236 192 protein complex amigo.geneontol...
GO GO:0031023 View Gene Set 1.813e-06 41 0.0001252 193 microtubule organizing center organization amigo.geneontol...
GO GO:0043021 View Gene Set 1.818e-06 39 0.0001252 193 ribonucleoprotein binding amigo.geneontol...
GO GO:0004984 View Gene Set 1.9e-06 419 0.0001302 195 olfactory receptor activity amigo.geneontol...
GO GO:0015934 View Gene Set 1.959e-06 64 0.0001335 196 large ribosomal subunit amigo.geneontol...
GO GO:0007080 View Gene Set 2.063e-06 11 0.0001392 197 mitotic metaphase plate congression amigo.geneontol...
GO GO:0015935 View Gene Set 2.058e-06 59 0.0001392 197 small ribosomal subunit amigo.geneontol...
GO GO:0043161 View Gene Set 2.143e-06 162 0.0001439 199 proteasomal ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0007608 View Gene Set 2.209e-06 432 0.0001476 200 sensory perception of smell amigo.geneontol...

Gene Set Collection: Broad.c1.CYTOBAND

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad chr11q12 View Gene Set 7.007e-06 179 0.002284 1 Genes in cytogenetic band chr11q12 www.broad.mit.e...
Broad chr9q34 View Gene Set 3.509e-05 204 0.003813 2 Genes in cytogenetic band chr9q34 www.broad.mit.e...
Broad chr17q25 View Gene Set 3.071e-05 172 0.003813 2 Genes in cytogenetic band chr17q25 www.broad.mit.e...
Broad chr19q13 View Gene Set 5.155e-05 765 0.004202 4 Genes in cytogenetic band chr19q13 www.broad.mit.e...
Broad chr17p13 View Gene Set 0.0003639 225 0.02372 5 Genes in cytogenetic band chr17p13 www.broad.mit.e...

Gene Set Collection: Broad.c2.CGP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad PUJANA_BRCA1_PCC_NETWORK View Gene Set 1.866e-78 1582 4.464e-75 1 Genes constituting the BRCA1-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA1 [Gene ID=672] across a compendium of normal tissues. www.broad.mit.e...
Broad PUJANA_CHEK2_PCC_NETWORK View Gene Set 6.178e-71 744 7.389e-68 2 Genes constituting the CHEK2-PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient PCC >= 0.4) with that of CHEK2 [Gene ID=11200]. www.broad.mit.e...
Broad MANALO_HYPOXIA_DN View Gene Set 5.924e-66 276 4.723e-63 3 Genes down-regulated in response to both hypoxia and overexpression of an active form of HIF1A [Gene ID=3091]. www.broad.mit.e...
Broad CAIRO_HEPATOBLASTOMA_CLASSES_UP View Gene Set 1.246e-65 577 7.451e-63 4 Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). www.broad.mit.e...
Broad DODD_NASOPHARYNGEAL_CARCINOMA_DN View Gene Set 1.159e-58 1253 5.546e-56 5 Genes down-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. www.broad.mit.e...
Broad KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP View Gene Set 2.919e-56 1180 1.164e-53 6 Genes up-regulated in TC71 and EWS502 cells (Ewing's sarcoma) upon knockdown of the EWSR1-FLII fusion [Gene ID=2130 2314]. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN View Gene Set 6.198e-45 920 2.118e-42 7 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h. www.broad.mit.e...
Broad WEI_MYCN_TARGETS_WITH_E_BOX View Gene Set 1.321e-42 757 3.949e-40 8 Genes whose promoters contain E-box motifs and whose expression changed in MYCN-3 cells (neuroblastoma) upon induction of MYCN [Gene ID=4613]. www.broad.mit.e...
Broad BERENJENO_TRANSFORMED_BY_RHOA_UP View Gene Set 5.998e-41 485 1.594e-38 9 Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [Gene ID=387] off plasmid vector. www.broad.mit.e...
Broad SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP View Gene Set 1.076e-40 143 2.573e-38 10 Up-regulated genes whose expression correlated with histologic grade of invasive breast cancer tumors: comparison of grade 1 vs grade 3. www.broad.mit.e...
Broad WONG_EMBRYONIC_STEM_CELL_CORE View Gene Set 3.547e-40 331 7.714e-38 11 The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module. www.broad.mit.e...
Broad KOBAYASHI_EGFR_SIGNALING_24HR_DN View Gene Set 1.454e-39 243 2.898e-37 12 Genes down-regulated in H1975 cells (non-small cell lung cancer NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 24h. www.broad.mit.e...
Broad PUJANA_BRCA2_PCC_NETWORK View Gene Set 3.908e-38 410 7.191e-36 13 Genes constituting the BRCA2-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA2 [Gene ID=675] across a compendium of normal tissues. www.broad.mit.e...
Broad ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER View Gene Set 7.701e-36 138 1.316e-33 14 The 'Cervical Cancer Proliferation Cluster' (CCPC): genes whose expression in cervical carcinoma positively correlates with that of the HPV E6 and E7 oncogenes; they are also differentially expressed according to disease outcome. www.broad.mit.e...
Broad SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 View Gene Set 4.439e-35 435 7.078e-33 15 Cluster 6 of method A: up-regulation of these genes in patients with non???small cell lung cancer (NSCLC) predicts poor survival outcome. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN View Gene Set 3.33e-29 832 4.978e-27 16 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. www.broad.mit.e...
Broad MUELLER_PLURINET View Gene Set 1.346e-28 294 1.894e-26 17 Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells embryonical carcinomas and induced pluripotent cells). www.broad.mit.e...
Broad BENPORATH_CYCLING_GENES View Gene Set 5.077e-28 630 6.746e-26 18 Genes showing cell-cycle stage-specific expression [PMID=12058064]. www.broad.mit.e...
Broad TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C View Gene Set 1.419e-26 436 1.786e-24 19 Genes down-regulated in HCT116 cells (colon cancer) upon expression of MIR34B or MIR34C [Gene ID=407041 407042] microRNAs. www.broad.mit.e...
Broad VECCHI_GASTRIC_CANCER_EARLY_UP View Gene Set 1.684e-26 408 2.013e-24 20 Up-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. www.broad.mit.e...
Broad PUJANA_XPRSS_INT_NETWORK View Gene Set 6.187e-26 164 7.047e-24 21 Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200] in a compendium of normal tissues. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP View Gene Set 1.394e-25 589 1.516e-23 22 Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. www.broad.mit.e...
Broad CROONQUIST_IL6_DEPRIVATION_DN View Gene Set 3.501e-25 80 3.642e-23 23 Genes down-regulated in the ANBL-6 cell line (multiple myeloma MM) after withdrawal of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad PUJANA_ATM_PCC_NETWORK View Gene Set 8.103e-24 1375 8.076e-22 24 Genes constituting the ATM-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of ATM [Gene ID=472] across a compendium of normal tissues. www.broad.mit.e...
Broad WINNEPENNINCKX_MELANOMA_METASTASIS_UP View Gene Set 3.544e-23 152 3.391e-21 25 Genes from the 254-gene classifier which were up-regulated in melanoma patients with a reported distant metastasis within 4 years. www.broad.mit.e...
Broad BIDUS_METASTASIS_UP View Gene Set 1.3e-22 203 1.196e-20 26 Genes up-regulated in endometroid endometrial tumors from patients with lymph node metastases compared to those without the metastases. www.broad.mit.e...
Broad GARY_CD5_TARGETS_DN View Gene Set 1.41e-22 415 1.249e-20 27 Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. www.broad.mit.e...
Broad WHITEFORD_PEDIATRIC_CANCER_MARKERS View Gene Set 1.63e-22 92 1.393e-20 28 Differentially expressed genes in a panel of xenografts representing 8 common pediatric tumors compared to the normal tissues. www.broad.mit.e...
Broad CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN View Gene Set 3.952e-22 639 3.26e-20 29 Genes down-regulated in APL (acute promyeolocytic leukemia) blasts expressing PML-RARA fusion [Gene ID=5371 5914] compared to normal promyeloblasts. www.broad.mit.e...
Broad BASAKI_YBX1_TARGETS_UP View Gene Set 7.614e-22 279 6.071e-20 30 Genes up-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [Gene ID=4904] knockdown by RNAi. www.broad.mit.e...
Broad KANG_DOXORUBICIN_RESISTANCE_UP View Gene Set 8.215e-22 53 6.339e-20 31 Genes differentialy expressed in gastric cancer cell lines: doxorubicin [PubChem=31703] resistant vs sensitive. www.broad.mit.e...
Broad FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP View Gene Set 1.517e-21 144 1.134e-19 32 Genes up-regulated in genomically unstable Ewing's sarcoma tumors compared to the stable ones. www.broad.mit.e...
Broad CROONQUIST_NRAS_SIGNALING_DN View Gene Set 2.762e-21 62 2.002e-19 33 Genes down-regulated in ANBL-6 cell line (multiple myeloma MM) expressing a constantly active form of NRAS [Gene ID=4893] off a plasmid vector compared to those grown in the presence of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad PUJANA_BRCA_CENTERED_NETWORK View Gene Set 5.17e-21 92 3.637e-19 34 Genes constituting the BRCA-centered network (BCN). www.broad.mit.e...
Broad GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP View Gene Set 6.635e-21 180 4.535e-19 35 Genes up-regulated in quiescent CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors compared to the dividing cells from CML (chronic myeloid leukemia) patients. www.broad.mit.e...
Broad FOURNIER_ACINAR_DEVELOPMENT_LATE_2 View Gene Set 4.026e-20 265 2.675e-18 36 Genes identified by method 2 as coordinately down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro. www.broad.mit.e...
Broad MISSIAGLIA_REGULATED_BY_METHYLATION_DN View Gene Set 5.696e-20 96 3.682e-18 37 Genes down-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668] a DNA hypomethylating agent similar to azacitidine [PubChem=9444]. www.broad.mit.e...
Broad GRADE_COLON_CANCER_UP View Gene Set 1.623e-19 711 1.022e-17 38 Up-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP View Gene Set 1.671e-19 184 1.025e-17 39 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G3 defined by unsupervised clustering. www.broad.mit.e...
Broad HORIUCHI_WTAP_TARGETS_DN View Gene Set 3.083e-19 289 1.843e-17 40 Genes down-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [Gene ID=9589] by RNAi. www.broad.mit.e...
Broad GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN View Gene Set 4.811e-19 86 2.807e-17 41 Genes down-regulated in quiescent vs dividing CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors. www.broad.mit.e...
Broad MARKEY_RB1_ACUTE_LOF_DN View Gene Set 8.726e-19 201 4.97e-17 42 Genes down-regulated in adult fibroblasts with inactivated RB1 [Gene ID=5925] by Cre-lox: acute loss of function (LOF) of RB1. www.broad.mit.e...
Broad HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP View Gene Set 2.41e-18 93 1.34e-16 43 Genes up-regulated during differentiation from large pre-BII to small pre-BII lymphocyte. www.broad.mit.e...
Broad TARTE_PLASMA_CELL_VS_PLASMABLAST_DN View Gene Set 6.876e-18 303 3.738e-16 44 Genes down-regulated in mature plasma cells compared with plasmablastic B lymphocytes. www.broad.mit.e...
Broad GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN View Gene Set 1.317e-17 148 6.998e-16 45 Genes down-regulated in the A673 cells (Ewing sarcoma) after double knockdown of both FLI1 and DAX1 [Gene ID=2313 190] by RNAi. www.broad.mit.e...
Broad BENPORATH_PROLIFERATION View Gene Set 2.323e-17 140 1.208e-15 46 Set 'Proliferation Cluster': genes defined in human breast tumor expression data. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM View Gene Set 4.125e-17 154 2.099e-15 47 Cluster 7: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] and down-regulated by the combination of MYC and serum. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN View Gene Set 6.687e-17 308 3.332e-15 48 Genes down-regulated in non-metastatic breast cancer tumors having type 1 amplification in the 20q13 region; involves ZNF217 [Gene ID=7764] locus only. www.broad.mit.e...
Broad BLUM_RESPONSE_TO_SALIRASIB_DN View Gene Set 1.086e-16 332 5.301e-15 49 Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [Gene ID=3265]. www.broad.mit.e...
Broad LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN View Gene Set 2.984e-16 158 1.427e-14 50 Genes down-regulated in Wilm's tumor samples compared to fetal kidney. www.broad.mit.e...
Broad FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN View Gene Set 3.216e-16 43 1.508e-14 51 Genes down-regulated in MCF-7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4-hydroxytamoxifen raloxifene or ICI 182780 but not by estradiol [PubChem=44959 5035 3478439 5757]. www.broad.mit.e...
Broad DANG_MYC_TARGETS_UP View Gene Set 1.064e-15 127 4.895e-14 52 Genes up-regulated by MYC [Gene ID=4609] and whose promoters are bound by MYC according to MYC Target Gene Database. www.broad.mit.e...
Broad MITSIADES_RESPONSE_TO_APLIDIN_DN View Gene Set 3.144e-15 241 1.419e-13 53 Genes down-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164] a marine-derived compound with potential anti-cancer properties. www.broad.mit.e...
Broad RUIZ_TNC_TARGETS_DN View Gene Set 5.853e-15 138 2.593e-13 54 Genes down-regulated in T98G cells (glioblastoma) by TNC [Gene ID=3371]. www.broad.mit.e...
Broad WELCSH_BRCA1_TARGETS_1_DN View Gene Set 6.527e-15 124 2.839e-13 55 Upregulated by induction of exogenous BRCA1 in EcR-293 cells www.broad.mit.e...
Broad FUJII_YBX1_TARGETS_DN View Gene Set 1.652e-14 139 7.055e-13 56 Genes down-regulated in MCF-7 cells (breast cancer) after knockdown of YBX1 [Gene ID=4904] by RNAi. www.broad.mit.e...
Broad CHANG_CYCLING_GENES View Gene Set 2.813e-14 49 1.181e-12 57 Fibroblast serum response genes showing periodic expression during the cell cycle; excluded from the core serum response signature. www.broad.mit.e...
Broad AMUNDSON_GAMMA_RADIATION_RESPONSE View Gene Set 3.548e-14 36 1.463e-12 58 Genes down-regulated across the entire panel of NCI-60 cell lines in response to gamma radiation. www.broad.mit.e...
Broad MORI_LARGE_PRE_BII_LYMPHOCYTE_UP View Gene Set 4.58e-14 52 1.857e-12 59 Up-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Large Pre-BII stage. www.broad.mit.e...
Broad CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP View Gene Set 1.12e-13 135 4.465e-12 60 Genes up-regulated in CD4+ [Gene ID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]. www.broad.mit.e...
Broad ODONNELL_TFRC_TARGETS_DN View Gene Set 2.658e-13 131 1.042e-11 61 Genes dpwn-regulated in P493-6 cells (B lymphocyte) upon knockdown of TFRC [Gene ID=7037] by RNAi. www.broad.mit.e...
Broad PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP View Gene Set 2.791e-13 53 1.077e-11 62 The XPRSS-Int network genes up-regulated in breast tumors from patients with germline mutations in BRCA1 [Gene ID=672] compared to those with the wild type allele. www.broad.mit.e...
Broad ZHAN_MULTIPLE_MYELOMA_PR_UP View Gene Set 4.457e-13 43 1.692e-11 63 Top 50 up-regulated genes in cluster PR of multiple myeloma samples characterized by increased expression of proliferation and cell cycle genes. www.broad.mit.e...
Broad FURUKAWA_DUSP6_TARGETS_PCI35_DN View Gene Set 1.272e-12 66 4.679e-11 64 Genes down-regulated in PCI-35 cells (pancreatic cancer lack endogenous DUSP6 [Gene ID=1848]) upon expression of DUSP6 off an adenoviral vector. www.broad.mit.e...
Broad KAUFFMANN_DNA_REPLICATION_GENES View Gene Set 1.259e-12 128 4.679e-11 64 Genes involved in DNA replication compiled manually by the authors. www.broad.mit.e...
Broad DANG_BOUND_BY_MYC View Gene Set 1.501e-12 1045 5.44e-11 66 Genes whose promoters are bound by MYC [Gene ID=4609] according to MYC Target Gene Database. www.broad.mit.e...
Broad REN_BOUND_BY_E2F View Gene Set 1.543e-12 47 5.508e-11 67 Genes whose promoters were bound by E2F1 [Gene ID=1869] and E2F4 [Gene ID=1874] in the primary fibroblasts WI-38 by ChIP on chip assay. www.broad.mit.e...
Broad MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP View Gene Set 8.525e-12 359 2.999e-10 68 The postradiation tumor escape signature: genes up-regulated in tumors from irradiated stroma vs those from non-irradiated stroma. www.broad.mit.e...
Broad MORI_IMMATURE_B_LYMPHOCYTE_DN View Gene Set 9.863e-12 52 3.406e-10 69 Down-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the immature B stage. www.broad.mit.e...
Broad WEST_ADRENOCORTICAL_TUMOR_UP View Gene Set 9.966e-12 283 3.406e-10 69 Up-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue. www.broad.mit.e...
Broad FARMER_BREAST_CANCER_CLUSTER_2 View Gene Set 1.083e-11 33 3.649e-10 71 Cluster 2: selected proliferation and 8q amplicon genes clustered together across breast cancer samples. www.broad.mit.e...
Broad ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN View Gene Set 1.434e-11 42 4.706e-10 72 Genes down-regulated in P493-6 cells (B lymphocyte) by MYC [Gene ID=4609] and up-regulated by RNAi knockdown of TFRC [Gene ID=7037]. www.broad.mit.e...
Broad LY_AGING_OLD_DN View Gene Set 1.436e-11 47 4.706e-10 72 Genes up-regulated in fibroblasts from old individuals compared to those from young donors. www.broad.mit.e...
Broad PENG_GLUTAMINE_DEPRIVATION_DN View Gene Set 1.959e-11 84 6.333e-10 74 Genes down-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation. www.broad.mit.e...
Broad KAUFFMANN_MELANOMA_RELAPSE_UP View Gene Set 3.039e-11 57 9.691e-10 75 DNA repair and replication genes up-regulated in melanoma patients who will relapse vs patients who will not. www.broad.mit.e...
Broad GRADE_COLON_AND_RECTAL_CANCER_UP View Gene Set 3.261e-11 213 1.026e-09 76 Up-regulated genes in both rectal and colon carcinoma compared to normal mucosa samples. www.broad.mit.e...
Broad MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN View Gene Set 3.764e-11 53 1.169e-09 77 Genes commonly down-regulated in SK-N-BE cells (neuroblastoma) after RNAi knockdown of CCND1 and CDK4 [Gene ID=595 1019]. www.broad.mit.e...
Broad LINDGREN_BLADDER_CANCER_CLUSTER_3_UP View Gene Set 6.697e-11 314 2.054e-09 78 Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_24HR_UP View Gene Set 1.356e-10 537 4.106e-09 79 Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h. www.broad.mit.e...
Broad SONG_TARGETS_OF_IE86_CMV_PROTEIN View Gene Set 1.403e-10 49 4.195e-09 80 Cellular genes up-regulated in forskin fibroblasts by expression of CMV EI86 protein off an adenovirus vector. www.broad.mit.e...
Broad KAUFFMANN_DNA_REPAIR_GENES View Gene Set 2.295e-10 205 6.776e-09 81 Genes involved in DNA repair compiled manually by the authors. www.broad.mit.e...
Broad PAL_PRMT5_TARGETS_UP View Gene Set 4.374e-10 178 1.276e-08 82 Genes up-regulated in NIH-3T3 cells (fibroblast) after knockdown of PRMT5 [Gene ID=10419] by RNAi. www.broad.mit.e...
Broad EGUCHI_CELL_CYCLE_RB1_TARGETS View Gene Set 8.966e-10 19 2.584e-08 83 RB1 [Gene ID=5925] target genes involved in cell cycle regulation: genes down-regulated by doxorubicin [PubChem=31703] only in cells expressing RB1. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP View Gene Set 1.052e-09 681 2.996e-08 84 Genes up-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue. www.broad.mit.e...
Broad BENPORATH_ES_1 View Gene Set 1.279e-09 367 3.601e-08 85 Set 'ES exp1': genes overexpressed in human embryonic stem cells according to 5 or more out of 20 profiling studies. www.broad.mit.e...
Broad YU_MYC_TARGETS_UP View Gene Set 1.463e-09 37 4.069e-08 86 Genes up-regulated in B cell lymphoma tumors expressing an activated form of MYC [Gene ID=4609]. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP View Gene Set 2.249e-09 45 6.184e-08 87 Cluster 5: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] alone or in combination with serum but not by serum alone. www.broad.mit.e...
Broad NUYTTEN_EZH2_TARGETS_DN View Gene Set 2.347e-09 859 6.38e-08 88 Genes down-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [Gene ID=2146] by RNAi. www.broad.mit.e...
Broad SCHUHMACHER_MYC_TARGETS_UP View Gene Set 3.246e-09 68 8.723e-08 89 Genes up-regulated in P493-6 cells (Burkitt's lymphoma) induced to express MYC [Gene ID=4609]. www.broad.mit.e...
Broad LEE_EARLY_T_LYMPHOCYTE_UP View Gene Set 6.854e-09 80 1.822e-07 90 Genes up-regulated at early stages of progenitor T lymphocyte maturation compared to the late stages. www.broad.mit.e...
Broad DANG_REGULATED_BY_MYC_UP View Gene Set 8.606e-09 65 2.262e-07 91 Genes up-regulated by MYC [Gene ID=4609] according to the MYC Target Gene Database. www.broad.mit.e...
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN View Gene Set 1.096e-08 51 2.848e-07 92 Genes from the turquoise module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphocholine (oxPAPC). www.broad.mit.e...
Broad LY_AGING_MIDDLE_DN View Gene Set 1.15e-08 15 2.958e-07 93 Genes down-regulated in fibroblasts from middle-age individuals compared to those from the young donors. www.broad.mit.e...
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP View Gene Set 1.222e-08 469 3.109e-07 94 Genes up-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. www.broad.mit.e...
Broad PUJANA_BREAST_CANCER_LIT_INT_NETWORK View Gene Set 2.197e-08 100 5.531e-07 95 Genes constituting the LIT-Int network of proteins interacting with breast cancer reference proteins BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200]; the interactions were manually curated from the literature. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN View Gene Set 4.982e-08 46 1.241e-06 96 Cluster 6: genes down-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] in combination with serum but not affected by serum alone; they are also up-regulated by MYC alone. www.broad.mit.e...
Broad ELVIDGE_HYPOXIA_DN View Gene Set 7.076e-08 136 1.745e-06 97 Genes down-regulated in MCF7 cells (breast cancer) under hypoxia conditions. www.broad.mit.e...
Broad RHODES_UNDIFFERENTIATED_CANCER View Gene Set 8.101e-08 60 1.977e-06 98 Genes commonly up-regulated in undifferentiated cancer relative to well-differentiated cancer based on the meta-analysis of the OncoMine gene expression database. www.broad.mit.e...
Broad MATTIOLI_MGUS_VS_PCL View Gene Set 9.639e-08 109 2.329e-06 99 Genes changed in MGUS (monoclonal gammopathy of undetermined significance) compared to PCL (plasma cell leukemia) samples. www.broad.mit.e...
Broad RIZ_ERYTHROID_DIFFERENTIATION View Gene Set 1.104e-07 71 2.641e-06 100 Selected gradually up-regulated genes in the TLX1 [Gene ID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). www.broad.mit.e...
Broad WONG_PROTEASOME_GENE_MODULE View Gene Set 1.711e-07 46 4.053e-06 101 Genes that comprise the proteasome gene module www.broad.mit.e...
Broad NAKAMURA_CANCER_MICROENVIRONMENT_DN View Gene Set 1.861e-07 45 4.364e-06 102 Genes down-regulated in pancreatic cancer cells grown in orthotopic xenograft tumors compared to those grown in vitro. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN View Gene Set 2.207e-07 160 5.125e-06 103 Genes down-regulated in metastatic breast cancer tumors having type 2 amplification in the 20q13 region; involves MYBL2 STK6 and ZNF217 [Gene ID=4605 6790 7764] www.broad.mit.e...
Broad ZHANG_BREAST_CANCER_PROGENITORS_UP View Gene Set 4.398e-07 370 1.011e-05 104 Genes changed in cancer stem cells isolated from mammary tumors compared to the non-tumorigenic cells. www.broad.mit.e...
Broad DAIRKEE_TERT_TARGETS_UP View Gene Set 4.756e-07 317 1.084e-05 105 Genes up-regulated in non-spontaneously immortalizing (NSI) primary breast cancer tumor cultures upon expression of TERT [Gene ID=7015] off a retroviral vector. www.broad.mit.e...
Broad CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP View Gene Set 5.261e-07 47 1.187e-05 106 Genes up-regulated by 2-methoxyestradiol (2ME2) [PubChem=1573] in the MM.1S cell line (multiple myeloma) sensitive to dexamethasone [PubChem=5743]. www.broad.mit.e...
Broad WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 View Gene Set 5.916e-07 36 1.322e-05 107 Genes downstream of both CDKN1A and TP53 [Gene ID=1026 7157] in 2774qw1 cells (ovarian cancer). www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 View Gene Set 6.603e-07 131 1.462e-05 108 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 14. www.broad.mit.e...
Broad BENPORATH_MYC_MAX_TARGETS View Gene Set 7.195e-07 768 1.579e-05 109 Set 'Myc targets2': targets of c-Myc [Gene ID=4609] and Max [Gene ID=4149] identified by ChIP on chip in a Burkitt???s lymphoma cell line; overlap set. www.broad.mit.e...
Broad FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN View Gene Set 7.861e-07 76 1.709e-05 110 Top 100 genes positively (UP) and negatively (DN) associated with T-cell acute lymphoblastic leukemia MLL T-ALL) expressing MLL-ENL fusion [Gene ID=4297 4298]. www.broad.mit.e...
Broad RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN View Gene Set 8.009e-07 351 1.726e-05 111 Genes down-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids. www.broad.mit.e...
Broad TANG_SENESCENCE_TP53_TARGETS_DN View Gene Set 1.023e-06 40 2.184e-05 112 Genes down-regulated in WI-38 cells (senescent primary fibroblasts) after inactivation of TP53 [Gene ID=7157] by GSE56 polypeptide. www.broad.mit.e...
Broad MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP View Gene Set 1.097e-06 92 2.323e-05 113 Genes correlated with the early tumor onset in the Emu-myc transgenic mouse lymphoma model. www.broad.mit.e...
Broad MENSSEN_MYC_TARGETS View Gene Set 1.158e-06 16 2.43e-05 114 Genes up-regulated by adenoviral expression of c-MYC [Gene ID=4609] in HUVEC cells (umbilical vein endothelium). www.broad.mit.e...
Broad SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY View Gene Set 1.566e-06 31 3.256e-05 115 Cluster 3: genes strongly up-regulated in B493-6 cells (B lymphocytes) by a combination of MYC [Gene ID=4609] and serum but not by each of them alone. www.broad.mit.e...
Broad CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP View Gene Set 2.374e-06 51 4.896e-05 116 Protein biosynthesis transport or catabolism genes up-regulated in hyperploid multiple myeloma (MM) compared to the non-hyperploid MM samples. www.broad.mit.e...
Broad CHANG_CORE_SERUM_RESPONSE_UP View Gene Set 2.57e-06 66 5.255e-05 117 Up-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group. www.broad.mit.e...
Broad BENPORATH_MYC_TARGETS_WITH_EBOX View Gene Set 3.383e-06 229 6.858e-05 118 Set 'Myc targets1': targets of c-Myc [Gene ID=4609] identified by ChIP on chip in cultured cell lines focusing on E-box???containing genes; high affinity bound subset www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP View Gene Set 3.467e-06 44 6.969e-05 119 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G123 defined by unsupervised clustering. www.broad.mit.e...
Broad LY_AGING_PREMATURE_DN View Gene Set 3.549e-06 24 7.075e-05 120 Genes down-regulated in fibroblasts from patients with Hutchinson-Gilford progeria (premature aging) compared to those from normal young individuals. www.broad.mit.e...
Broad NADERI_BREAST_CANCER_PROGNOSIS_UP View Gene Set 3.901e-06 37 7.711e-05 121 Up-regulated genes in the breast cancer prognostic signature of 70 genes that significantly correlated with survival. www.broad.mit.e...
Broad FINETTI_BREAST_CANCER_KINOME_RED View Gene Set 3.986e-06 15 7.753e-05 122 Genes in the red cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. www.broad.mit.e...
Broad FINETTI_BREAST_CANCER_BASAL_VS_LUMINAL View Gene Set 3.986e-06 15 7.753e-05 122 Protein kinases distinguishing between basal and luminal A subtypes of breast cancer. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 View Gene Set 4.351e-06 165 8.394e-05 124 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 17. www.broad.mit.e...
Broad LE_EGR2_TARGETS_UP View Gene Set 4.569e-06 100 8.742e-05 125 Genes up-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [Gene ID=1959]. www.broad.mit.e...
Broad SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN View Gene Set 5.792e-06 22 0.00011 126 Cell cycle genes changed in H1299 cells (lung cancer) after overexpression of either P53 [Gene ID=7157] or P73 [Gene ID=7161]. www.broad.mit.e...
Broad ZHANG_RESPONSE_TO_CANTHARIDIN_DN View Gene Set 6.262e-06 60 0.0001179 127 Genes down-regulated in HL-60 cells (promyeloid leukemia) by cantharidin [PubChem=6708701]. www.broad.mit.e...
Broad CAFFAREL_RESPONSE_TO_THC_DN View Gene Set 6.916e-06 25 0.0001292 128 Genes down-regulated in EVSA-T cells (breast cancer) treated THC (delta-9-tetrahydrocannabinol) [PubChem=6610319]. www.broad.mit.e...
Broad SMID_BREAST_CANCER_LUMINAL_A_DN View Gene Set 7.117e-06 17 0.000132 129 Genes down-regulated in the luminal A subtype of breast cancer. www.broad.mit.e...
Broad HESS_TARGETS_OF_HOXA9_AND_MEIS1_UP View Gene Set 7.511e-06 59 0.0001382 130 Genes up-regulated in hematopoietic precursor cells conditionally expressing HOXA9 and MEIS1 [Gene ID=3205 4211]. www.broad.mit.e...
Broad MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN View Gene Set 9.9e-06 42 0.0001808 131 Genes down-regulated in normal bone marrow plasma cells (BMPC) compared to polyclonal plasmablasts (PPC) that also distinguished multiple myeloma (MM) samples by expression of levels of TACI [Gene ID=23495]. www.broad.mit.e...
Broad MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN View Gene Set 1.17e-05 212 0.0002119 132 Genes down-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199]. www.broad.mit.e...
Broad POMEROY_MEDULLOBLASTOMA_PROGNOSIS_DN View Gene Set 1.263e-05 39 0.0002272 133 Top marker genes in medulloblastoma associated with poor response to treatment (poor outcome). www.broad.mit.e...
Broad PENG_RAPAMYCIN_RESPONSE_DN View Gene Set 1.304e-05 69 0.0002327 134 Genes down-regulated in BJUB cells (B-lymphoma) in response to rapamycin [PubChem=6610346] treatment. www.broad.mit.e...
Broad DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2 View Gene Set 1.585e-05 111 0.00028 135 'Cancer prone response profile' (CPRP): genes common to estradiol and bisphenol A [PubChem=5757 6623] response of epithelial cell cultures from patients at high risk of breast cancer. www.broad.mit.e...
Broad CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP View Gene Set 1.592e-05 135 0.00028 135 Top 200 marker genes up-regulated in the 'proliferation' subclass of hepatocellular carcinoma (HCC); characterized by increased proliferation high levels of serum AFP [Gene ID=174] and chromosomal instability. www.broad.mit.e...
Broad GEORGES_CELL_CYCLE_MIR192_TARGETS View Gene Set 1.914e-05 59 0.0003342 137 Experimentally validated direct targets of MIR192 [Gene ID=406967] microRNA; MIR192 caused cell cycle arrest in HCT116 cells (colon cancer). www.broad.mit.e...
Broad LEE_METASTASIS_AND_RNA_PROCESSING_UP View Gene Set 2.026e-05 15 0.0003512 138 Components of RNA post-transcriptional modification machinery up-regulated in MDA-MB-435 cells (breast cancer) whose metastatic potential has been reduced by expression of NME1 [Gene ID=4830]. www.broad.mit.e...
Broad RHODES_CANCER_META_SIGNATURE View Gene Set 2.091e-05 54 0.0003598 139 Genes commonly up-regulated in cancer relative to normal tissue according to the meta-analysis of the OncoMine gene expression database. www.broad.mit.e...
Broad BHATTACHARYA_EMBRYONIC_STEM_CELL View Gene Set 2.303e-05 76 0.0003935 140 The 'stemnes' signature: genes up-regulated and common to 6 human embryonic stem cell lines tested. www.broad.mit.e...
Broad PENG_LEUCINE_DEPRIVATION_DN View Gene Set 2.406e-05 50 0.0004081 141 Genes down-regulated in BJAB cells (B-lymphoma) after leucine [PubChem=857] deprivation. www.broad.mit.e...
Broad KUMAMOTO_RESPONSE_TO_NUTLIN_3A_DN View Gene Set 3.128e-05 10 0.000527 142 Genes down-regulated in response to nutlin-3a [PubChem=216345] an inhibitor of MDM2 [Gene ID=4193] in skin fibroblast cultures after knockdown of TP53 [Gene ID=7157] by RNAi. www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_14HR_UP View Gene Set 3.346e-05 150 0.0005596 143 Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not up-regulated at the previous time point 12 h. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP View Gene Set 3.793e-05 52 0.0006301 144 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G23 defined by unsupervised clustering. www.broad.mit.e...
Broad RIZ_ERYTHROID_DIFFERENTIATION_CCNE1 View Gene Set 4.726e-05 38 0.0007797 145 Selected gradually up-regulated genes whose expression profile follows that of CCNE1 [Gene ID=898] in the TLX1 [Gene ID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). www.broad.mit.e...
Broad SCHLOSSER_SERUM_RESPONSE_AUGMENTED_BY_MYC View Gene Set 4.883e-05 101 0.0008 146 Cluster 2: genes up-regulated in B493-6 cells (B lymphocytes) by serum alone or in combination with MYC [Gene ID=4609] but not by MYC alone. www.broad.mit.e...
Broad HSIAO_HOUSEKEEPING_GENES View Gene Set 5.889e-05 384 0.0009582 147 Housekeeping genes identified as expressed across 19 normal tissues. www.broad.mit.e...
Broad ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN View Gene Set 6.586e-05 61 0.001064 148 Genes down-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 View Gene Set 6.712e-05 93 0.001077 149 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 11. www.broad.mit.e...
Broad BILD_MYC_ONCOGENIC_SIGNATURE View Gene Set 7.795e-05 187 0.001243 150 Genes selected in supervised analyses to discriminate cells expressing c-Myc [Gene ID=4609] from control cells expressing GFP. www.broad.mit.e...
Broad SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP View Gene Set 8.623e-05 269 0.001366 151 Genes up-regulated in nsopharyngeal carcinoma relative to the normal tissue. www.broad.mit.e...
Broad LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP View Gene Set 8.771e-05 168 0.00138 152 Genes with copy number gains in primary neuroblastoma tumors. www.broad.mit.e...
Broad SEMBA_FHIT_TARGETS_DN View Gene Set 9.143e-05 10 0.001429 153 Genes down-regulated in H1299 cells (non-small cell lung cancer NSCLC) expressing the Y144F mutant form of FHIT [Gene ID=2272]. www.broad.mit.e...
Broad MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP View Gene Set 0.0001176 10 0.001827 154 Up-regulated genes predicting poor survival of patients with thyroid carcinoma. www.broad.mit.e...
Broad ZHAN_MULTIPLE_MYELOMA_SUBGROUPS View Gene Set 0.0001604 28 0.002475 155 Top genes up-regulated in MM4 vs MM1 subgroup of multiple myeloma samples. www.broad.mit.e...
Broad DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP View Gene Set 0.0001715 1353 0.00263 156 Genes up-regulated in CD34+ [Gene ID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients compared to those from normal donors. www.broad.mit.e...
Broad STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN View Gene Set 0.0001985 41 0.003006 157 Genes down-regulated by estradiol [PubChem=5757] and down-regulated by ESRRA [Gene ID=2101] in MCF-7 cells (breast cancer). www.broad.mit.e...
Broad RAMALHO_STEMNESS_UP View Gene Set 0.000198 192 0.003006 157 Genes enriched in embryonic neural and hematopoietic stem cells. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP View Gene Set 0.0002183 36 0.003263 159 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_DN View Gene Set 0.0002183 36 0.003263 159 Down-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors. www.broad.mit.e...
Broad CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN View Gene Set 0.0002807 81 0.004152 161 Genes down-regulated in ANBL-6 cell line (multiple myeloma MM) expressing an activated form of NRAS [Gene ID=4893] off a plasmid vector compared to those co-cultured with bone marrow stromal cells. www.broad.mit.e...
Broad LEE_LIVER_CANCER_SURVIVAL_DN View Gene Set 0.0002812 123 0.004152 161 Genes highly expressed in hepatocellular carcinoma with poor survival. www.broad.mit.e...
Broad GOLDRATH_ANTIGEN_RESPONSE View Gene Set 0.0002881 315 0.004202 163 Genes up-regulated at the peak of an antigen response of naive CD8+ [Gene ID=925 926] T-cells. www.broad.mit.e...
Broad CHIARETTI_T_ALL_RELAPSE_PROGNOSIS View Gene Set 0.0002867 12 0.004202 163 Genes whose expression predicted relapse in less than 2 years after chemotherapy for adult patients with T-ALL (T cell lymphoblastic leukemia). www.broad.mit.e...
Broad SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP View Gene Set 0.0003377 45 0.004895 165 Top 50 up-regulated markers distinguishing diffuse large B-cell lymphoma (DLBCL) from follicular lymphoma (FL) samples. www.broad.mit.e...
Broad NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP View Gene Set 0.000358 263 0.005133 166 Up-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone. www.broad.mit.e...
Broad OLSSON_E2F3_TARGETS_DN View Gene Set 0.0003583 28 0.005133 166 Genes down-regulated in the 5637 cell line (bladder cancer) after knockdown of E2F3 [Gene ID=1871] by RNAi. www.broad.mit.e...
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_DN View Gene Set 0.0003925 24 0.005588 168 Genes from the green module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC). www.broad.mit.e...
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP View Gene Set 0.0004019 26 0.005655 169 Genes from the magenta module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC). www.broad.mit.e...
Broad KIM_GASTRIC_CANCER_CHEMOSENSITIVITY View Gene Set 0.0003998 97 0.005655 169 Genes up-regulated in gastric cancer patients refractory to chemotherapy treatment with 5-fluorouracil and cisplatin [PubChem=3385 2767] compared to the sensitive state. www.broad.mit.e...
Broad OHASHI_AURKB_TARGETS View Gene Set 0.0004076 8 0.005702 171 Candidate substrate proteins of AURKB [Gene ID=9212]. www.broad.mit.e...
Broad BORCZUK_MALIGNANT_MESOTHELIOMA_UP View Gene Set 0.0004184 290 0.005819 172 Genes up-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma. www.broad.mit.e...
Broad LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER View Gene Set 0.0004224 167 0.005841 173 Overexpressed genes with amplified copy number across 27 non-small cell lung cancer (NSCLC) cell lines. www.broad.mit.e...
Broad ELVIDGE_HIF1A_TARGETS_UP View Gene Set 0.0004759 64 0.006543 174 Genes up-regulated in MCF7 cells (breast cancer) after knockdown of HIF1A [Gene ID=3091] by RNAi. www.broad.mit.e...
Broad PODAR_RESPONSE_TO_ADAPHOSTIN_DN View Gene Set 0.0005008 17 0.006846 175 Down-regulated genes in MM1.S cells (multiple myeloma) treated with adaphostin [PubChem=387042] a tyrosine kinase inhibitor with anticancer properties. www.broad.mit.e...
Broad LOPEZ_MBD_TARGETS View Gene Set 0.0005206 855 0.007076 176 Genes up-regulated in HeLa cells (cervical cancer) after simultaneus knockdown of all three MBD (methyl-CpG binding domain) proteins MeCP2 MBD1 and MBD2 [Gene ID=4204 4152 8932] by RNAi. www.broad.mit.e...
Broad WAKASUGI_HAVE_ZNF143_BINDING_SITES View Gene Set 0.0005442 55 0.007355 177 DNA repair genes whose promoters contain putative ZNF143 [Gene ID=7702] binding sites. www.broad.mit.e...
Broad BASSO_B_LYMPHOCYTE_NETWORK View Gene Set 0.0005801 136 0.007796 178 Genes which comprise the top 1% of highly interconnected genes (major hubs) that account for most of gene interactions in the reconstructed regulatory networks from expression profiles in B lymphocytes. www.broad.mit.e...
Broad MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN View Gene Set 0.0005868 121 0.007841 179 Genes distinguishing in multiple myeloma (MM) samples with lower expression of TACI [Gene ID=23495]. www.broad.mit.e...
Broad JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_UP View Gene Set 0.00059 45 0.007841 179 Up-regulated genes distinguishing between breast cancer tumors with mutated BRCA1 [Gene ID=672] from those with mutated BRCA2 [Gene ID=675]. www.broad.mit.e...
Broad JISON_SICKLE_CELL_DISEASE_DN View Gene Set 0.0006644 168 0.008781 181 Genes down-regulated in peripheral blood mononuclear cells (PBMC) from sickle cell disease patients compared to those from healthy subjects. www.broad.mit.e...
Broad LIN_APC_TARGETS View Gene Set 0.0007192 52 0.009453 182 Genes up-regulated by forced expression of APC [Gene ID=324] in the APC-deficient SW480 cell line (colon cancer). www.broad.mit.e...
Broad PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP View Gene Set 0.0008379 175 0.01095 183 Up-regulated genes in head and neck cancer compared to cervical carcinoma samples. www.broad.mit.e...
Broad SHEPARD_CRUSH_AND_BURN_MUTANT_DN View Gene Set 0.000876 147 0.01139 184 Human orthologs of genes down-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [Gene ID=4605]. www.broad.mit.e...
Broad SHEPARD_BMYB_TARGETS View Gene Set 0.0009119 60 0.01179 185 Human orthologs of BMYB [Gene ID=4605] target genes in zebra fish identified as commonly changed in the BMYB loss of function mutant crb ('crush and burn') and after knockdown of BMYB by morpholino. www.broad.mit.e...
Broad MORI_MATURE_B_LYMPHOCYTE_DN View Gene Set 0.000923 56 0.01187 186 Down-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the mature B www.broad.mit.e...
Broad HEIDENBLAD_AMPLICON_8Q24_UP View Gene Set 0.0009397 29 0.01196 187 Up-regulated genes whose expression is associated with amplification of the 8q24 chromosome region in pancreatic cancer cell lines. www.broad.mit.e...
Broad BENPORATH_ES_2 View Gene Set 0.000936 39 0.01196 187 Set 'Set 'ES exp2': genes overexpressed in human embryonic stem cells according to a meta-analysis of 8 profiling studies. www.broad.mit.e...
Broad COLDREN_GEFITINIB_RESISTANCE_UP View Gene Set 0.0009701 74 0.01228 189 Genes up-regulated in NSCLC (non-small cell lung carcinoma) cell lines resistant to gefitinib [PubChem=123631] compared to the sensitive ones. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_6HR_UP View Gene Set 0.001064 50 0.01339 190 Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 6h. www.broad.mit.e...
Broad SU_TESTIS View Gene Set 0.001134 75 0.0142 191 Genes up-regulated specifically in human testis tissue. www.broad.mit.e...
Broad NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP View Gene Set 0.001188 87 0.0148 192 Top 100 probe sets contrubuting to the positive side of the 2nd principal component; associated with adipocytic differentiation. www.broad.mit.e...
Broad IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR View Gene Set 0.001195 100 0.01481 193 Genes in the expression cluster 'Early Progenitors Shared': up-regulated in hematopoietic progenitors from adult bone marrow and from fetal liver. www.broad.mit.e...
Broad MEINHOLD_OVARIAN_CANCER_LOW_GRADE_DN View Gene Set 0.001484 18 0.0183 194 Genes down-regulated in low grade (LMP and G1) serous ovarian carcinomas vs the higher grade invasive tumors (G2 and G3). www.broad.mit.e...
Broad GOLDRATH_HOMEOSTATIC_PROLIFERATION View Gene Set 0.001581 154 0.01939 195 Up-regulated in CD8+ [Gene ID=925] T lymphocytes undergoing homeostatic proliferation (HP) versus the naive cells; these genes are not up-regulated versus effector or memory cell population. www.broad.mit.e...
Broad SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP View Gene Set 0.001761 16 0.02149 196 Genes up-regulated in MCF10A cells (breast cancer) grown at low (mesenchymal phenotype) compared to those grown at high (epithelial basal-like phenotype) confluency. www.broad.mit.e...
Broad LIU_SOX4_TARGETS_DN View Gene Set 0.001814 297 0.02203 197 Genes down-regulated in LNCaP cells (prostate cancer) by overexpression of SOX4 [Gene ID=6659] and up-regulated by its RNAi knockdown. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7 View Gene Set 0.001978 65 0.0239 198 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 7. www.broad.mit.e...
Broad FOURNIER_ACINAR_DEVELOPMENT_LATE_DN View Gene Set 0.002093 21 0.02516 199 Genes down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro. www.broad.mit.e...
Broad PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN View Gene Set 0.002292 49 0.02741 200 Antigen processing and presentation genes down-regulated in JY cells (B lymphocytes) treated with trichostatin A (TSA) [PubChem=5562]. www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.BIOCARTA

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad BIOCARTA_RANMS_PATHWAY View Gene Set 1.153e-06 10 0.0002501 1 Role of Ran in mitotic spindle regulation www.broad.mit.e...
Broad BIOCARTA_EIF_PATHWAY View Gene Set 8.108e-06 16 0.0008797 2 Eukaryotic protein translation www.broad.mit.e...
Broad BIOCARTA_ATRBRCA_PATHWAY View Gene Set 0.0001698 21 0.01228 3 Role of BRCA1 BRCA2 and ATR in Cancer Susceptibility www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.KEGG

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad KEGG_SPLICEOSOME View Gene Set 1.009e-20 118 1.877e-18 1 Spliceosome www.broad.mit.e...
Broad KEGG_CELL_CYCLE View Gene Set 2.883e-09 128 2.682e-07 2 Cell cycle www.broad.mit.e...
Broad KEGG_PROTEASOME View Gene Set 1.585e-07 48 9.825e-06 3 Proteasome www.broad.mit.e...
Broad KEGG_PYRIMIDINE_METABOLISM View Gene Set 1.368e-06 98 5.877e-05 4 Pyrimidine metabolism www.broad.mit.e...
Broad KEGG_RNA_DEGRADATION View Gene Set 1.58e-06 59 5.877e-05 4 RNA degradation www.broad.mit.e...
Broad KEGG_DNA_REPLICATION View Gene Set 2.28e-06 36 7.068e-05 6 DNA replication www.broad.mit.e...
Broad KEGG_AMINOACYL_TRNA_BIOSYNTHESIS View Gene Set 1.077e-05 41 0.0002861 7 Aminoacyl-tRNA biosynthesis www.broad.mit.e...
Broad KEGG_MISMATCH_REPAIR View Gene Set 5.145e-05 23 0.001063 8 Mismatch repair www.broad.mit.e...
Broad KEGG_OLFACTORY_TRANSDUCTION View Gene Set 4.785e-05 389 0.001063 8 Olfactory transduction www.broad.mit.e...
Broad KEGG_HOMOLOGOUS_RECOMBINATION View Gene Set 6.087e-05 28 0.001132 10 Homologous recombination www.broad.mit.e...
Broad KEGG_BASE_EXCISION_REPAIR View Gene Set 8.025e-05 35 0.001357 11 Base excision repair www.broad.mit.e...
Broad KEGG_RIBOSOME View Gene Set 0.0003302 88 0.005118 12 Ribosome www.broad.mit.e...
Broad KEGG_ONE_CARBON_POOL_BY_FOLATE View Gene Set 0.0006498 17 0.009297 13 One carbon pool by folate www.broad.mit.e...
Broad KEGG_NUCLEOTIDE_EXCISION_REPAIR View Gene Set 0.002296 44 0.0305 14 Nucleotide excision repair www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.REACTOME

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad REACTOME_CELL_CYCLE_MITOTIC View Gene Set 8.399e-34 306 1.806e-31 1 Genes involved in Cell Cycle Mitotic www.broad.mit.e...
Broad REACTOME_GENE_EXPRESSION View Gene Set 7.961e-34 415 1.806e-31 1 Genes involved in Gene Expression www.broad.mit.e...
Broad REACTOME_MITOTIC_M_M_G1_PHASES View Gene Set 8.067e-33 157 1.156e-30 3 Genes involved in Mitotic M-M/G1 phases www.broad.mit.e...
Broad REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA View Gene Set 3.469e-25 128 3.729e-23 4 Genes involved in Processing of Capped Intron-Containing Pre-mRNA www.broad.mit.e...
Broad REACTOME_MITOTIC_PROMETAPHASE View Gene Set 5.478e-20 92 4.711e-18 5 Genes involved in Mitotic Prometaphase www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING View Gene Set 7.859e-20 97 5.632e-18 6 Genes involved in mRNA Splicing www.broad.mit.e...
Broad REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS View Gene Set 6.532e-19 124 4.012e-17 7 Genes involved in Elongation and Processing of Capped Transcripts www.broad.mit.e...
Broad REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT View Gene Set 6.356e-17 142 3.416e-15 8 Genes involved in Formation and Maturation of mRNA Transcript www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_RNA View Gene Set 4.564e-16 95 2.181e-14 9 Genes involved in Metabolism of RNA www.broad.mit.e...
Broad REACTOME_CELL_CYCLE_CHECKPOINTS View Gene Set 3.384e-15 110 1.455e-13 10 Genes involved in Cell Cycle Checkpoints www.broad.mit.e...
Broad REACTOME_M_G1_TRANSITION View Gene Set 3.621e-13 61 1.416e-11 11 Genes involved in M/G1 Transition www.broad.mit.e...
Broad REACTOME_G1_S_TRANSITION View Gene Set 1.508e-12 102 4.99e-11 12 Genes involved in G1/S Transition www.broad.mit.e...
Broad REACTOME_SYNTHESIS_OF_DNA View Gene Set 1.458e-12 89 4.99e-11 12 Genes involved in Synthesis of DNA www.broad.mit.e...
Broad REACTOME_DNA_REPLICATION_PRE_INITIATION View Gene Set 1.845e-12 76 5.667e-11 14 Genes involved in DNA Replication Pre-Initiation www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION View Gene Set 3.446e-12 188 9.878e-11 15 Genes involved in Transcription www.broad.mit.e...
Broad REACTOME_TRANSLATION View Gene Set 8.477e-12 120 2.278e-10 16 Genes involved in Translation www.broad.mit.e...
Broad REACTOME_S_PHASE View Gene Set 1.017e-11 103 2.573e-10 17 Genes involved in S Phase www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_PROTEINS View Gene Set 9.985e-11 215 2.385e-09 18 Genes involved in Metabolism of proteins www.broad.mit.e...
Broad REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX View Gene Set 2.783e-10 52 6.299e-09 19 Genes involved in CDT1 association with the CDC6:ORC:origin complex www.broad.mit.e...
Broad REACTOME_ORC1_REMOVAL_FROM_CHROMATIN View Gene Set 5.868e-10 63 1.201e-08 20 Genes involved in Orc1 removal from chromatin www.broad.mit.e...
Broad REACTOME_SNRNP_ASSEMBLY View Gene Set 5.765e-10 50 1.201e-08 20 Genes involved in snRNP Assembly www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRON_CONTAINING_TRANSCRIPT View Gene Set 7.448e-10 42 1.456e-08 22 Genes involved in Transport of Mature mRNA derived from an Intron-Containing Transcript www.broad.mit.e...
Broad REACTOME_REGULATION_OF_APC_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE View Gene Set 1.112e-09 71 2.079e-08 23 Genes involved in Regulation of APC/C activators between G1/S and early anaphase www.broad.mit.e...
Broad REACTOME_G2_M_CHECKPOINTS View Gene Set 2.43e-09 43 4.353e-08 24 Genes involved in G2/M Checkpoints www.broad.mit.e...
Broad REACTOME_CDC20_PHOSPHO_APC_MEDIATED_DEGRADATION_OF_CYCLIN_A View Gene Set 2.982e-09 63 5.129e-08 25 Genes involved in Cdc20:Phospho-APC/C mediated degradation of Cyclin A www.broad.mit.e...
Broad REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT View Gene Set 5.457e-09 106 8.694e-08 26 Genes involved in GTP hydrolysis and joining of the 60S ribosomal subunit www.broad.mit.e...
Broad REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS View Gene Set 5.459e-09 120 8.694e-08 26 Genes involved in Host Interactions of HIV factors www.broad.mit.e...
Broad REACTOME_TELOMERE_MAINTENANCE View Gene Set 1.007e-08 77 1.547e-07 28 Genes involved in Telomere Maintenance www.broad.mit.e...
Broad REACTOME_HIV_INFECTION View Gene Set 1.624e-08 183 2.408e-07 29 Genes involved in HIV Infection www.broad.mit.e...
Broad REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 View Gene Set 2.429e-08 48 3.482e-07 30 Genes involved in SCF-beta-TrCP mediated degradation of Emi1 www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS View Gene Set 3.925e-08 37 5.31e-07 31 Genes involved in Activation of ATR in response to replication stress www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_III_AND_MITOCHONDRIAL_TRANSCRIPTION View Gene Set 3.951e-08 120 5.31e-07 31 Genes involved in RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription www.broad.mit.e...
Broad REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC View Gene Set 4.941e-08 57 6.438e-07 33 Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_MRNA View Gene Set 7.625e-08 45 9.643e-07 34 Genes involved in Metabolism of mRNA www.broad.mit.e...
Broad REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION View Gene Set 1.434e-07 56 1.762e-06 35 Genes involved in Translation initiation complex formation www.broad.mit.e...
Broad REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE View Gene Set 1.592e-07 43 1.85e-06 36 Genes involved in p53-Independent DNA Damage Response www.broad.mit.e...
Broad REACTOME_TRNA_AMINOACYLATION View Gene Set 1.589e-07 40 1.85e-06 36 Genes involved in tRNA Aminoacylation www.broad.mit.e...
Broad REACTOME_INFLUENZA_LIFE_CYCLE View Gene Set 1.855e-07 137 2.045e-06 38 Genes involved in Influenza Life Cycle www.broad.mit.e...
Broad REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE View Gene Set 1.814e-07 47 2.045e-06 38 Genes involved in Regulation of ornithine decarboxylase (ODC) www.broad.mit.e...
Broad REACTOME_REV_MEDIATED_NUCLEAR_EXPORT_OF_HIV1_RNA View Gene Set 3.14e-07 31 3.375e-06 40 Genes involved in Rev-mediated nuclear export of HIV-1 RNA www.broad.mit.e...
Broad REACTOME_STABILIZATION_OF_P53 View Gene Set 3.242e-07 46 3.4e-06 41 Genes involved in Stabilization of p53 www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_THE_SLBP_INDEPENDENT_MATURE_MRNA View Gene Set 3.354e-07 32 3.434e-06 42 Genes involved in Transport of the SLBP independent Mature mRNA www.broad.mit.e...
Broad REACTOME_SIGNALING_BY_WNT View Gene Set 3.86e-07 58 3.86e-06 43 Genes involved in Signaling by Wnt www.broad.mit.e...
Broad REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN View Gene Set 4.433e-07 30 4.333e-06 44 Genes involved in Nuclear import of Rev protein www.broad.mit.e...
Broad REACTOME_MRNA_3_END_PROCESSING View Gene Set 5.142e-07 25 4.913e-06 45 Genes involved in mRNA 3-end processing www.broad.mit.e...
Broad REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION View Gene Set 6.264e-07 23 5.855e-06 46 Genes involved in Cytosolic tRNA aminoacylation www.broad.mit.e...
Broad REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G View Gene Set 1.28e-06 47 1.147e-05 47 Genes involved in Vif-mediated degradation of APOBEC3G www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS View Gene Set 1.279e-06 29 1.147e-05 47 Genes involved in Transport of Ribonucleoproteins into the Host Nucleus www.broad.mit.e...
Broad REACTOME_OLFACTORY_SIGNALING_PATHWAY View Gene Set 1.532e-06 371 1.344e-05 49 Genes involved in Olfactory Signaling Pathway www.broad.mit.e...
Broad REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21 View Gene Set 1.614e-06 52 1.38e-05 50 Genes involved in SCF(Skp2)-mediated degradation of p2721 www.broad.mit.e...
Broad REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY View Gene Set 1.637e-06 29 1.38e-05 50 Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery www.broad.mit.e...
Broad REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS View Gene Set 2.36e-06 95 1.951e-05 52 Genes involved in Formation of a pool of free 40S subunits www.broad.mit.e...
Broad REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING View Gene Set 4.102e-06 50 3.328e-05 53 Genes involved in Chaperonin-mediated protein folding www.broad.mit.e...
Broad REACTOME_DNA_STRAND_ELONGATION View Gene Set 1.39e-05 31 0.0001107 54 Genes involved in DNA strand elongation www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_PROMOTER_OPENING View Gene Set 1.445e-05 59 0.000113 55 Genes involved in RNA Polymerase I Promoter Opening www.broad.mit.e...
Broad REACTOME_METABLISM_OF_NUCLEOTIDES View Gene Set 1.769e-05 71 0.0001348 56 Genes involved in Metablism of nucleotides www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_PROMOTER_CLEARANCE View Gene Set 1.787e-05 82 0.0001348 56 Genes involved in RNA PolymerasePromoter Clearance www.broad.mit.e...
Broad REACTOME_PACKAGING_OF_TELOMERE_ENDS View Gene Set 2.087e-05 49 0.0001547 58 Genes involved in Packaging Of Telomere Ends www.broad.mit.e...
Broad REACTOME_G2_M_TRANSITION View Gene Set 2.258e-05 84 0.0001646 59 Genes involved in G2/M Transition www.broad.mit.e...
Broad REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC View Gene Set 2.301e-05 22 0.0001649 60 Genes involved in Formation of tubulin folding intermediates by CCT/TriC www.broad.mit.e...
Broad REACTOME_VPR_MEDIATED_NUCLEAR_IMPORT_OF_PICS View Gene Set 2.402e-05 31 0.0001693 61 Genes involved in Vpr-mediated nuclear import of PICs www.broad.mit.e...
Broad REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX View Gene Set 2.849e-05 49 0.0001976 62 Genes involved in Formation of the ternary complex and subsequently the 43S complex www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX View Gene Set 3.174e-05 30 0.0002166 63 Genes involved in Activation of the pre-replicative complex www.broad.mit.e...
Broad REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE View Gene Set 3.286e-05 90 0.0002174 64 Genes involved in Late Phase of HIV Life Cycle www.broad.mit.e...
Broad REACTOME_UNWINDING_OF_DNA View Gene Set 3.273e-05 11 0.0002174 64 Genes involved in Unwinding of DNA www.broad.mit.e...
Broad REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION View Gene Set 3.764e-05 33 0.0002415 66 Genes involved in E2F mediated regulation of DNA replication www.broad.mit.e...
Broad REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN View Gene Set 3.718e-05 29 0.0002415 66 Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING_MINOR_PATHWAY View Gene Set 3.877e-05 38 0.0002452 68 Genes involved in mRNA Splicing - Minor Pathway www.broad.mit.e...
Broad REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC View Gene Set 4.265e-05 28 0.0002658 69 Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC www.broad.mit.e...
Broad REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS View Gene Set 4.642e-05 29 0.0002852 70 Genes involved in Association of TriC/CCT with target proteins during biosynthesis www.broad.mit.e...
Broad REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ View Gene Set 4.89e-05 58 0.0002921 71 Genes involved in Cyclin E associated events during G1/S transition www.broad.mit.e...
Broad REACTOME_E2F_TRANSCRIPTIONAL_TARGETS_AT_G1_S View Gene Set 4.835e-05 22 0.0002921 71 Genes involved in E2F transcriptional targets at G1/S www.broad.mit.e...
Broad REACTOME_EXTENSION_OF_TELOMERES View Gene Set 5.178e-05 28 0.000305 73 Genes involved in Extension of Telomeres www.broad.mit.e...
Broad REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC:ORIGIN_COMPLEX View Gene Set 5.566e-05 11 0.0003234 74 Genes involved in CDC6 association with the ORC:origin complex www.broad.mit.e...
Broad REACTOME_PEPTIDE_CHAIN_ELONGATION View Gene Set 6.426e-05 84 0.0003684 75 Genes involved in Peptide chain elongation www.broad.mit.e...
Broad REACTOME_HIV_LIFE_CYCLE View Gene Set 7.942e-05 103 0.0004493 76 Genes involved in HIV Life Cycle www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION View Gene Set 8.572e-05 83 0.0004787 77 Genes involved in RNA Polymerase II Transcription www.broad.mit.e...
Broad REACTOME_CENTROSOME_MATURATION View Gene Set 8.866e-05 72 0.0004887 78 Genes involved in Centrosome maturation www.broad.mit.e...
Broad REACTOME_GLUCOSE_TRANSPORT View Gene Set 0.0001053 38 0.000573 79 Genes involved in Glucose transport www.broad.mit.e...
Broad REACTOME_DNA_REPAIR View Gene Set 0.0001611 102 0.0008661 80 Genes involved in DNA Repair www.broad.mit.e...
Broad REACTOME_APOPTOSIS View Gene Set 0.000377 129 0.002001 81 Genes involved in Apoptosis www.broad.mit.e...
Broad REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES View Gene Set 0.0004154 11 0.002178 82 Genes involved in Recruitment of NuMA to mitotic centrosomes www.broad.mit.e...
Broad REACTOME_DOUBLE_STRAND_BREAK_REPAIR View Gene Set 0.0004295 21 0.002225 83 Genes involved in Double-Strand Break Repair www.broad.mit.e...
Broad REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR View Gene Set 0.0004377 15 0.002241 84 Genes involved in Homologous Recombination Repair www.broad.mit.e...
Broad REACTOME_DEADENYLATION_OF_MRNA View Gene Set 0.0004563 21 0.002308 85 Genes involved in Deadenylation of mRNA www.broad.mit.e...
Broad REACTOME_VIRAL_MRNA_TRANSLATION View Gene Set 0.0004762 84 0.002381 86 Genes involved in Viral mRNA Translation www.broad.mit.e...
Broad REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PREREPLICATIVE_COMPLEX View Gene Set 0.0005504 12 0.00272 87 Genes involved in Association of licensing factors with the pre-replicative complex www.broad.mit.e...
Broad REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION View Gene Set 0.0006359 100 0.003107 88 Genes involved in Influenza Viral RNA Transcription and Replication www.broad.mit.e...
Broad REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS View Gene Set 0.0007446 11 0.003597 89 Genes involved in Purine ribonucleoside monophosphate biosynthesis www.broad.mit.e...
Broad REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES View Gene Set 0.0008785 18 0.004197 90 Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates www.broad.mit.e...
Broad REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION View Gene Set 0.001133 10 0.005352 91 Genes involved in E2F-enabled inhibition of pre-replication complex formation www.broad.mit.e...
Broad REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT View Gene Set 0.001163 114 0.005435 92 Genes involved in Regulation of beta-cell development www.broad.mit.e...
Broad REACTOME_REPAIR_SYNTHESIS_OF_PATCH_27_30_BASES_LONG_BY_DNA_POLYMERASE View Gene Set 0.001277 15 0.005905 93 Genes involved in Repair synthesis of patch ~27-30 bases long by DNA polymerase www.broad.mit.e...
Broad REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE View Gene Set 0.001872 11 0.008564 94 Genes involved in mRNA Decay by 3' to 5' Exoribonuclease www.broad.mit.e...
Broad REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE View Gene Set 0.002096 13 0.009485 95 Genes involved in mRNA Decay by 5' to 3' Exoribonuclease www.broad.mit.e...
Broad REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS View Gene Set 0.002198 101 0.009844 96 Genes involved in Regulation of gene expression in beta cells www.broad.mit.e...
Broad REACTOME_PYRIMIDINE_METABOLISM View Gene Set 0.002396 22 0.01062 97 Genes involved in Pyrimidine metabolism www.broad.mit.e...
Broad REACTOME_INACTIVATION_OF_APC_VIA_DIRECT_INHIBITION_OF_THE_APCOMPLEX View Gene Set 0.00277 18 0.01215 98 Genes involved in Inactivation of APC/C via direct inhibition of the APC/C complex www.broad.mit.e...
Broad REACTOME_MTOR_SIGNALLING View Gene Set 0.003064 27 0.01331 99 Genes involved in mTOR signalling www.broad.mit.e...
Broad REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES View Gene Set 0.00324 62 0.01393 100 Genes involved in Loss of Nlp from mitotic centrosomes www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_CARBOHYDRATES View Gene Set 0.007494 119 0.03191 101 Genes involved in Metabolism of carbohydrates www.broad.mit.e...
Broad REACTOME_CYCLIN_A1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION View Gene Set 0.007868 15 0.03317 102 Genes involved in Cyclin A1 associated events during G2/M transition www.broad.mit.e...
Broad REACTOME_MTORC1_MEDIATED_SIGNALLING View Gene Set 0.009374 11 0.03914 103 Genes involved in mTORC1-mediated signalling www.broad.mit.e...
Broad REACTOME_MICRORNA_BIOGENESIS View Gene Set 0.01047 18 0.0433 104 Genes involved in MicroRNA biogenesis www.broad.mit.e...
Broad REACTOME_NUCLEOTIDE_EXCISION_REPAIR View Gene Set 0.01087 49 0.0445 105 Genes involved in Nucleotide Excision Repair www.broad.mit.e...
Broad REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION View Gene Set 0.0121 20 0.04908 106 Genes involved in Mitochondrial tRNA aminoacylation www.broad.mit.e...

Gene Set Collection: Broad.c3.TFT

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad V$E2F_Q4 View Gene Set 2.868e-15 166 1.764e-12 1 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F_Q6 View Gene Set 9.038e-15 165 2.779e-12 2 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1_Q6_01 View Gene Set 1.655e-13 177 3.394e-11 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTTCGCGCS which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F1_Q4_01 View Gene Set 2.707e-13 167 4.161e-11 4 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1_Q6 View Gene Set 1.544e-12 167 1.899e-10 5 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGS which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F_03 View Gene Set 2.408e-12 171 2.468e-10 6 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGCGMNR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F_Q3_01 View Gene Set 2.974e-12 171 2.613e-10 7 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F_Q4_01 View Gene Set 1.117e-11 171 7.992e-10 8 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCSCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F_Q6_01 View Gene Set 1.169e-11 167 7.992e-10 8 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKCGCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F_Q3 View Gene Set 2.297e-11 162 1.413e-09 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTCGCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1_Q3 View Gene Set 3.344e-11 176 1.869e-09 11 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKTSSCGC which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F_02 View Gene Set 5.816e-11 169 2.425e-09 12 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1DP1_01 View Gene Set 5.914e-11 169 2.425e-09 12 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1DP2_01 View Gene Set 5.914e-11 169 2.425e-09 12 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) www.broad.mit.e...
Broad V$E2F4DP2_01 View Gene Set 5.914e-11 169 2.425e-09 12 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) www.broad.mit.e...
Broad V$E2F1DP1RB_01 View Gene Set 1.094e-10 168 4.207e-09 16 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) www.broad.mit.e...
Broad CACGTG_V$MYC_Q2 View Gene Set 1.29e-10 734 4.666e-09 17 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CACGTG which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian) www.broad.mit.e...
Broad GCCATNTTG_V$YY1_Q6 View Gene Set 4.121e-10 289 1.408e-08 18 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTG which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad V$MYCMAX_01 View Gene Set 5.359e-10 189 1.735e-08 19 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNACCACGTGGTNN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X www.broad.mit.e...
Broad SGCGSSAAA_V$E2F1DP2_01 View Gene Set 7.931e-10 122 2.439e-08 20 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SGCGSSAAA which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) www.broad.mit.e...
Broad V$E2F4DP1_01 View Gene Set 1.298e-09 174 3.801e-08 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1_Q4 View Gene Set 1.876e-06 178 5.245e-05 22 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTSGCGG which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad SCGGAAGY_V$ELK1_02 View Gene Set 2.106e-06 784 5.632e-05 23 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SCGGAAGY which matches annotation for ELK1: ELK1 member of ETS oncogene family www.broad.mit.e...
Broad RCGCANGCGY_V$NRF1_Q6 View Gene Set 2.259e-06 580 5.789e-05 24 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RCGCANGCGY which matches annotation for NRF1: nuclear respiratory factor 1 www.broad.mit.e...
Broad V$NFMUE1_Q6 View Gene Set 4.306e-06 175 0.0001059 25 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CGGCCATCT. Motif does not match any known transcription factor www.broad.mit.e...
Broad KRCTCNNNNMANAGC_UNKNOWN View Gene Set 5.673e-06 60 0.0001342 26 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KRCTCNNNNMANAGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MAX_01 View Gene Set 1.311e-05 194 0.0002987 27 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNANCACGTGNTNN which matches annotation for MAX: MYC associated factor X www.broad.mit.e...
Broad V$YY1_Q6 View Gene Set 1.365e-05 166 0.0002997 28 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTN which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad V$E2F_01 View Gene Set 2.003e-05 55 0.0004247 29 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TWSGCGCGAAAAYKR. Motif does not match any known transcription factor www.broad.mit.e...
Broad GCGSCMNTTT_UNKNOWN View Gene Set 3.809e-05 49 0.0007809 30 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GCGSCMNTTT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF_01 View Gene Set 4.12e-05 186 0.0008174 31 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNRYCACGTGRYNN. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF_C View Gene Set 6.581e-05 211 0.001265 32 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NCACGTGN. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$ARNT_01 View Gene Set 0.0001424 196 0.002654 33 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NDDNNCACGTGNNNNN which matches annotation for ARNT: aryl hydrocarbon receptor nuclear translocator www.broad.mit.e...
Broad V$MYC_Q2 View Gene Set 0.0001897 135 0.003432 34 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CACGTGS which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian) www.broad.mit.e...
Broad TCCCRNNRTGC_UNKNOWN View Gene Set 0.0002823 130 0.00496 35 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TCCCRNNRTGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad KTGGYRSGAA_UNKNOWN View Gene Set 0.0004094 53 0.006993 36 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KTGGYRSGAA. Motif does not match any known transcription factor www.broad.mit.e...
Broad GGCNKCCATNK_UNKNOWN View Gene Set 0.0004387 84 0.007293 37 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGCNKCCATNK. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$NMYC_01 View Gene Set 0.0004589 201 0.007426 38 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNCCACGTGNNN which matches annotation for MYCN: v-myc myelocytomatosis viral related oncogene neuroblastoma derived (avian) www.broad.mit.e...
Broad KCCGNSWTTT_UNKNOWN View Gene Set 0.0004953 76 0.007615 39 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KCCGNSWTTT. Motif does not match any known transcription factor www.broad.mit.e...
Broad RRCCGTTA_UNKNOWN View Gene Set 0.0004843 53 0.007615 39 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif RRCCGTTA. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF2_Q6 View Gene Set 0.0005506 182 0.008259 41 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CASGYG. Motif does not match any known transcription factor www.broad.mit.e...
Broad GATGKMRGCG_UNKNOWN View Gene Set 0.0006934 47 0.01015 42 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GATGKMRGCG. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$YY1_02 View Gene Set 0.0009953 168 0.01424 43 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNCGGCCATCTTGNCTSNW which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad ATCMNTCCGY_UNKNOWN View Gene Set 0.001077 36 0.01506 44 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ATCMNTCCGY. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$GABP_B View Gene Set 0.001207 162 0.01649 45 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif VCCGGAAGNGCR which matches annotation for GABPA: GA binding protein transcription factor alpha subunit 60kDa<br> GABPB2: GA binding protein transcription factor beta subunit 2 www.broad.mit.e...
Broad V$GR_01 View Gene Set 0.001279 154 0.0171 46 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNNNGKACNNNNTGTTCTNNNNNN which matches annotation for NR3C1: nuclear receptor subfamily 3 group C member 1 (glucocorticoid receptor) www.broad.mit.e...
Broad V$ARNT_02 View Gene Set 0.001412 179 0.01809 47 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNRTCACGTGAYNNNNN which matches annotation for ARNT: aryl hydrocarbon receptor nuclear translocator www.broad.mit.e...
Broad V$USF_Q6_01 View Gene Set 0.001388 168 0.01809 47 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NRCCACGTGASN. Motif does not match any known transcription factor www.broad.mit.e...
Broad AAGWWRNYGGC_UNKNOWN View Gene Set 0.001632 85 0.02007 49 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif AAGWWRNYGGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MYCMAX_B View Gene Set 0.001627 193 0.02007 49 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCAYGYGSN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X www.broad.mit.e...
Broad TTCNRGNNNNTTC_V$HSF_Q6 View Gene Set 0.001777 111 0.02143 51 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTCNRGNNNNTTC. Motif does not match any known transcription factor www.broad.mit.e...
Broad GKCGCNNNNNNNTGAYG_UNKNOWN View Gene Set 0.001944 41 0.023 52 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GKCGCNNNNNNNTGAYG. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF_Q6 View Gene Set 0.002113 178 0.02452 53 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GYCACGTGNC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MYCMAX_03 View Gene Set 0.002949 187 0.03358 54 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNNNCACGTGNNNNNNN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X www.broad.mit.e...
Broad V$CMYB_01 View Gene Set 0.003495 179 0.03908 55 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCNRNNGRCNGTTGGKGG which matches annotation for MYB: v-myb myeloblastosis viral oncogene homolog (avian) www.broad.mit.e...
Broad V$MAZ_Q6 View Gene Set 0.003561 135 0.03911 56 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGGGAGGG which matches annotation for MAZ: MYC-associated zinc finger protein (purine-binding transcription factor) www.broad.mit.e...
Broad GGAANCGGAANY_UNKNOWN View Gene Set 0.004248 79 0.04583 57 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGAANCGGAANY. Motif does not match any known transcription factor www.broad.mit.e...
Broad TAANNYSGCG_UNKNOWN View Gene Set 0.004359 60 0.04622 58 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TAANNYSGCG. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF_02 View Gene Set 0.004751 197 0.04952 59 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNRNCACGTGNYNN. Motif does not match any known transcription factor www.broad.mit.e...

Gene Set Collection: Broad.c4.CGN

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad MORF_BUB3 View Gene Set 4.519e-34 256 1.93e-31 1 Neighborhood of BUB3 www.broad.mit.e...
Broad MORF_EIF3S2 View Gene Set 4.146e-32 220 8.852e-30 2 Neighborhood of EIF3S2 www.broad.mit.e...
Broad MORF_UBE2I View Gene Set 4.557e-30 208 6.486e-28 3 Neighborhood of UBE2I www.broad.mit.e...
Broad GNF2_SMC4L1 View Gene Set 2.168e-28 75 2.314e-26 4 Neighborhood of SMC4L1 www.broad.mit.e...
Broad MORF_FBL View Gene Set 7.698e-28 121 6.574e-26 5 Neighborhood of FBL www.broad.mit.e...
Broad GNF2_RRM1 View Gene Set 1.239e-27 82 8.82e-26 6 Neighborhood of RRM1 www.broad.mit.e...
Broad MORF_PRKDC View Gene Set 9.687e-27 173 5.909e-25 7 Neighborhood of PRKDC www.broad.mit.e...
Broad MORF_AATF View Gene Set 1.197e-26 179 6.387e-25 8 Neighborhood of AATF www.broad.mit.e...
Broad MORF_RAD23A View Gene Set 1.388e-26 316 6.586e-25 9 Neighborhood of RAD23A www.broad.mit.e...
Broad GNF2_CCNB2 View Gene Set 6.742e-26 53 2.879e-24 10 Neighborhood of CCNB2 www.broad.mit.e...
Broad GNF2_CCNA2 View Gene Set 1.424e-25 62 5.527e-24 11 Neighborhood of CCNA2 www.broad.mit.e...
Broad GNF2_CDC20 View Gene Set 1.617e-25 52 5.754e-24 12 Neighborhood of CDC20 www.broad.mit.e...
Broad GNF2_PCNA View Gene Set 5.759e-25 62 1.892e-23 13 Neighborhood of PCNA www.broad.mit.e...
Broad GNF2_CENPF View Gene Set 2.056e-24 56 6.27e-23 14 Neighborhood of CENPF www.broad.mit.e...
Broad MORF_HDAC2 View Gene Set 1.396e-23 256 3.975e-22 15 Neighborhood of HDAC2 www.broad.mit.e...
Broad GNF2_RAN View Gene Set 2.321e-23 78 6.195e-22 16 Neighborhood of RAN www.broad.mit.e...
Broad GNF2_CDC2 View Gene Set 4.147e-23 56 1.042e-21 17 Neighborhood of CDC2 www.broad.mit.e...
Broad GNF2_PA2G4 View Gene Set 3.407e-22 73 8.083e-21 18 Neighborhood of PA2G4 www.broad.mit.e...
Broad MORF_ANP32B View Gene Set 9.274e-22 174 2.084e-20 19 Neighborhood of ANP32B www.broad.mit.e...
Broad GNF2_MCM4 View Gene Set 2.185e-21 50 4.664e-20 20 Neighborhood of MCM4 www.broad.mit.e...
Broad GNF2_HMMR View Gene Set 6.056e-21 43 1.231e-19 21 Neighborhood of HMMR www.broad.mit.e...
Broad MORF_ACP1 View Gene Set 7.531e-21 178 1.462e-19 22 Neighborhood of ACP1 www.broad.mit.e...
Broad GNF2_BUB1B View Gene Set 3.938e-20 46 7.311e-19 23 Neighborhood of BUB1B www.broad.mit.e...
Broad MORF_RFC4 View Gene Set 6.68e-20 137 1.189e-18 24 Neighborhood of RFC4 www.broad.mit.e...
Broad GNF2_FEN1 View Gene Set 1.004e-19 49 1.714e-18 25 Neighborhood of FEN1 www.broad.mit.e...
Broad GNF2_RFC4 View Gene Set 1.505e-19 57 2.472e-18 26 Neighborhood of RFC4 www.broad.mit.e...
Broad MORF_CSNK2B View Gene Set 1.922e-19 256 3.04e-18 27 Neighborhood of CSNK2B www.broad.mit.e...
Broad MORF_DNMT1 View Gene Set 7.785e-19 105 1.187e-17 28 Neighborhood of DNMT1 www.broad.mit.e...
Broad MORF_DEK View Gene Set 1.08e-18 229 1.591e-17 29 Neighborhood of DEK www.broad.mit.e...
Broad MORF_PPP1CC View Gene Set 1.99e-18 150 2.833e-17 30 Neighborhood of PPP1CC www.broad.mit.e...
Broad GNF2_ESPL1 View Gene Set 6.134e-18 35 8.45e-17 31 Neighborhood of ESPL1 www.broad.mit.e...
Broad GNF2_CKS2 View Gene Set 7.288e-18 45 9.725e-17 32 Neighborhood of CKS2 www.broad.mit.e...
Broad MORF_RAD54L View Gene Set 9.51e-18 94 1.23e-16 33 Neighborhood of RAD54L www.broad.mit.e...
Broad GNF2_RRM2 View Gene Set 2.635e-17 36 3.31e-16 34 Neighborhood of RRM2 www.broad.mit.e...
Broad GCM_APEX1 View Gene Set 2.971e-17 102 3.624e-16 35 Neighborhood of APEX1 www.broad.mit.e...
Broad MORF_HAT1 View Gene Set 6.841e-17 155 7.894e-16 36 Neighborhood of HAT1 www.broad.mit.e...
Broad GNF2_TTK View Gene Set 6.815e-17 34 7.894e-16 36 Neighborhood of TTK www.broad.mit.e...
Broad MORF_PCNA View Gene Set 7.129e-17 71 8.011e-16 38 Neighborhood of PCNA www.broad.mit.e...
Broad GNF2_MCM5 View Gene Set 8.031e-17 51 8.793e-16 39 Neighborhood of MCM5 www.broad.mit.e...
Broad MORF_SOD1 View Gene Set 1.018e-16 247 1.087e-15 40 Neighborhood of SOD1 www.broad.mit.e...
Broad GNF2_CENPE View Gene Set 2.14e-16 37 2.228e-15 41 Neighborhood of CENPE www.broad.mit.e...
Broad GNF2_CKS1B View Gene Set 2.464e-16 36 2.505e-15 42 Neighborhood of CKS1B www.broad.mit.e...
Broad MORF_XRCC5 View Gene Set 2.726e-16 210 2.707e-15 43 Neighborhood of XRCC5 www.broad.mit.e...
Broad GNF2_APEX1 View Gene Set 4.51e-16 72 4.377e-15 44 Neighborhood of APEX1 www.broad.mit.e...
Broad GNF2_NPM1 View Gene Set 7.487e-16 57 7.104e-15 45 Neighborhood of NPM1 www.broad.mit.e...
Broad GNF2_DEK View Gene Set 9.558e-16 45 8.872e-15 46 Neighborhood of DEK www.broad.mit.e...
Broad MORF_G22P1 View Gene Set 1.078e-15 145 9.797e-15 47 Neighborhood of G22P1 www.broad.mit.e...
Broad MORF_ESPL1 View Gene Set 1.772e-15 58 1.577e-14 48 Neighborhood of ESPL1 www.broad.mit.e...
Broad MORF_NPM1 View Gene Set 2.114e-15 152 1.842e-14 49 Neighborhood of NPM1 www.broad.mit.e...
Broad MORF_RAN View Gene Set 2.422e-15 242 2.068e-14 50 Neighborhood of RAN www.broad.mit.e...
Broad GNF2_FBL View Gene Set 3.74e-15 119 3.132e-14 51 Neighborhood of FBL www.broad.mit.e...
Broad MORF_RRM1 View Gene Set 1.729e-14 90 1.42e-13 52 Neighborhood of RRM1 www.broad.mit.e...
Broad GNF2_RFC3 View Gene Set 2.287e-14 38 1.843e-13 53 Neighborhood of RFC3 www.broad.mit.e...
Broad MORF_FEN1 View Gene Set 4.075e-14 58 3.222e-13 54 Neighborhood of FEN1 www.broad.mit.e...
Broad MORF_RPA2 View Gene Set 4.31e-14 170 3.346e-13 55 Neighborhood of RPA2 www.broad.mit.e...
Broad GNF2_H2AFX View Gene Set 6.015e-14 28 4.587e-13 56 Neighborhood of H2AFX www.broad.mit.e...
Broad GNF2_BUB1 View Gene Set 6.905e-14 25 5.172e-13 57 Neighborhood of BUB1 www.broad.mit.e...
Broad MORF_GNB1 View Gene Set 7.28e-14 276 5.36e-13 58 Neighborhood of GNB1 www.broad.mit.e...
Broad MORF_CDK2 View Gene Set 3.597e-13 63 2.603e-12 59 Neighborhood of CDK2 www.broad.mit.e...
Broad GNF2_MKI67 View Gene Set 7.145e-13 26 5.085e-12 60 Neighborhood of MKI67 www.broad.mit.e...
Broad MORF_DDB1 View Gene Set 8.914e-13 220 6.139e-12 61 Neighborhood of DDB1 www.broad.mit.e...
Broad GNF2_MLH1 View Gene Set 8.831e-13 36 6.139e-12 61 Neighborhood of MLH1 www.broad.mit.e...
Broad GCM_ACTG1 View Gene Set 1.04e-12 113 7.05e-12 63 Neighborhood of ACTG1 www.broad.mit.e...
Broad MORF_PHB View Gene Set 2.177e-12 112 1.453e-11 64 Neighborhood of PHB www.broad.mit.e...
Broad GNF2_MSH6 View Gene Set 2.662e-12 30 1.749e-11 65 Neighborhood of MSH6 www.broad.mit.e...
Broad MORF_UNG View Gene Set 3.073e-12 65 1.988e-11 66 Neighborhood of UNG www.broad.mit.e...
Broad GCM_CSNK2B View Gene Set 6.194e-12 88 3.947e-11 67 Neighborhood of CSNK2B www.broad.mit.e...
Broad MORF_SART1 View Gene Set 6.982e-12 55 4.384e-11 68 Neighborhood of SART1 www.broad.mit.e...
Broad GNF2_SMC2L1 View Gene Set 9.354e-12 30 5.788e-11 69 Neighborhood of SMC2L1 www.broad.mit.e...
Broad GNF2_HAT1 View Gene Set 1.9e-11 45 1.159e-10 70 Neighborhood of HAT1 www.broad.mit.e...
Broad GNF2_KPNB1 View Gene Set 2.398e-11 52 1.442e-10 71 Neighborhood of KPNB1 www.broad.mit.e...
Broad MORF_MSH2 View Gene Set 3.371e-11 52 1.999e-10 72 Neighborhood of MSH2 www.broad.mit.e...
Broad MORF_EI24 View Gene Set 5.094e-11 136 2.98e-10 73 Neighborhood of EI24 www.broad.mit.e...
Broad MORF_HDAC1 View Gene Set 5.64e-11 222 3.255e-10 74 Neighborhood of HDAC1 www.broad.mit.e...
Broad MORF_SMC1L1 View Gene Set 6.261e-11 47 3.565e-10 75 Neighborhood of SMC1L1 www.broad.mit.e...
Broad GNF2_XRCC5 View Gene Set 8.421e-11 61 4.731e-10 76 Neighborhood of XRCC5 www.broad.mit.e...
Broad GNF2_HDAC1 View Gene Set 1.129e-10 85 6.259e-10 77 Neighborhood of HDAC1 www.broad.mit.e...
Broad MORF_BUB1B View Gene Set 1.262e-10 61 6.909e-10 78 Neighborhood of BUB1B www.broad.mit.e...
Broad MORF_USP5 View Gene Set 1.859e-10 46 1.005e-09 79 Neighborhood of USP5 www.broad.mit.e...
Broad MORF_BUB1 View Gene Set 2.585e-10 49 1.38e-09 80 Neighborhood of BUB1 www.broad.mit.e...
Broad MORF_PPP2CA View Gene Set 3.129e-10 110 1.65e-09 81 Neighborhood of PPP2CA www.broad.mit.e...
Broad GCM_NPM1 View Gene Set 4.345e-10 108 2.262e-09 82 Neighborhood of NPM1 www.broad.mit.e...
Broad MORF_CUL1 View Gene Set 4.55e-10 62 2.341e-09 83 Neighborhood of CUL1 www.broad.mit.e...
Broad MORF_DAP3 View Gene Set 7.222e-10 175 3.671e-09 84 Neighborhood of DAP3 www.broad.mit.e...
Broad MORF_PRKAG1 View Gene Set 9.968e-10 202 5.008e-09 85 Neighborhood of PRKAG1 www.broad.mit.e...
Broad GNF2_DAP3 View Gene Set 1.28e-09 98 6.354e-09 86 Neighborhood of DAP3 www.broad.mit.e...
Broad GNF2_ANP32B View Gene Set 1.732e-09 29 8.499e-09 87 Neighborhood of ANP32B www.broad.mit.e...
Broad GNF2_NS View Gene Set 1.863e-09 35 9.038e-09 88 Neighborhood of NS www.broad.mit.e...
Broad MORF_NME2 View Gene Set 2.364e-09 145 1.134e-08 89 Neighborhood of NME2 www.broad.mit.e...
Broad MORF_ACTG1 View Gene Set 4.112e-09 134 1.951e-08 90 Neighborhood of ACTG1 www.broad.mit.e...
Broad MORF_CCNI View Gene Set 4.568e-09 76 2.143e-08 91 Neighborhood of CCNI www.broad.mit.e...
Broad GNF2_MSH2 View Gene Set 7.667e-09 26 3.559e-08 92 Neighborhood of MSH2 www.broad.mit.e...
Broad MORF_RAD21 View Gene Set 8.376e-09 157 3.846e-08 93 Neighborhood of RAD21 www.broad.mit.e...
Broad MORF_CTBP1 View Gene Set 1.016e-08 149 4.613e-08 94 Neighborhood of CTBP1 www.broad.mit.e...
Broad GNF2_G22P1 View Gene Set 1.047e-08 29 4.705e-08 95 Neighborhood of G22P1 www.broad.mit.e...
Broad GNF2_EIF3S6 View Gene Set 1.425e-08 109 6.337e-08 96 Neighborhood of EIF3S6 www.broad.mit.e...
Broad GNF2_RBBP6 View Gene Set 1.685e-08 54 7.419e-08 97 Neighborhood of RBBP6 www.broad.mit.e...
Broad MORF_PTPN11 View Gene Set 1.9e-08 93 8.278e-08 98 Neighborhood of PTPN11 www.broad.mit.e...
Broad MORF_GSPT1 View Gene Set 1.941e-08 41 8.37e-08 99 Neighborhood of GSPT1 www.broad.mit.e...
Broad MORF_EIF3S6 View Gene Set 2.054e-08 108 8.769e-08 100 Neighborhood of EIF3S6 www.broad.mit.e...
Broad MORF_CDC16 View Gene Set 2.584e-08 67 1.092e-07 101 Neighborhood of CDC16 www.broad.mit.e...
Broad MORF_GMPS View Gene Set 2.613e-08 48 1.094e-07 102 Neighborhood of GMPS www.broad.mit.e...
Broad MORF_RAF1 View Gene Set 2.65e-08 94 1.099e-07 103 Neighborhood of RAF1 www.broad.mit.e...
Broad MORF_EIF4A2 View Gene Set 2.836e-08 120 1.142e-07 104 Neighborhood of EIF4A2 www.broad.mit.e...
Broad MORF_UBE2N View Gene Set 2.801e-08 79 1.142e-07 104 Neighborhood of UBE2N www.broad.mit.e...
Broad GNF2_TDG View Gene Set 2.819e-08 23 1.142e-07 104 Neighborhood of TDG www.broad.mit.e...
Broad MORF_MAP2K2 View Gene Set 4.021e-08 123 1.605e-07 107 Neighborhood of MAP2K2 www.broad.mit.e...
Broad MORF_TERF1 View Gene Set 4.762e-08 57 1.883e-07 108 Neighborhood of TERF1 www.broad.mit.e...
Broad MORF_CDC10 View Gene Set 5.737e-08 120 2.247e-07 109 Neighborhood of CDC10 www.broad.mit.e...
Broad GNF2_ST13 View Gene Set 7.169e-08 56 2.783e-07 110 Neighborhood of ST13 www.broad.mit.e...
Broad GCM_PPP1CC View Gene Set 7.551e-08 47 2.905e-07 111 Neighborhood of PPP1CC www.broad.mit.e...
Broad MORF_SNRP70 View Gene Set 1.306e-07 50 4.98e-07 112 Neighborhood of SNRP70 www.broad.mit.e...
Broad MORF_ERH View Gene Set 1.668e-07 103 6.304e-07 113 Neighborhood of ERH www.broad.mit.e...
Broad GNF2_ELAC2 View Gene Set 1.923e-07 32 7.204e-07 114 Neighborhood of ELAC2 www.broad.mit.e...
Broad GCM_RAF1 View Gene Set 2.562e-07 34 9.513e-07 115 Neighborhood of RAF1 www.broad.mit.e...
Broad GCM_CBFB View Gene Set 2.723e-07 59 1.002e-06 116 Neighborhood of CBFB www.broad.mit.e...
Broad GNF2_DENR View Gene Set 3.417e-07 39 1.247e-06 117 Neighborhood of DENR www.broad.mit.e...
Broad GNF2_RPA1 View Gene Set 4.801e-07 20 1.737e-06 118 Neighborhood of RPA1 www.broad.mit.e...
Broad MORF_DEAF1 View Gene Set 5.153e-07 54 1.849e-06 119 Neighborhood of DEAF1 www.broad.mit.e...
Broad GCM_PSME1 View Gene Set 5.854e-07 76 2.083e-06 120 Neighborhood of PSME1 www.broad.mit.e...
Broad GCM_DDX5 View Gene Set 1.138e-06 52 4.015e-06 121 Neighborhood of DDX5 www.broad.mit.e...
Broad MORF_RPA1 View Gene Set 1.497e-06 55 5.24e-06 122 Neighborhood of RPA1 www.broad.mit.e...
Broad GNF2_PPP6C View Gene Set 2.326e-06 33 8.076e-06 123 Neighborhood of PPP6C www.broad.mit.e...
Broad MORF_CCNF View Gene Set 2.449e-06 65 8.434e-06 124 Neighborhood of CCNF www.broad.mit.e...
Broad GNF2_BUB3 View Gene Set 3.025e-06 22 1.033e-05 125 Neighborhood of BUB3 www.broad.mit.e...
Broad GCM_ANP32B View Gene Set 3.823e-06 32 1.295e-05 126 Neighborhood of ANP32B www.broad.mit.e...
Broad MORF_PSMC1 View Gene Set 4.067e-06 162 1.367e-05 127 Neighborhood of PSMC1 www.broad.mit.e...
Broad MORF_PPP1CA View Gene Set 9.427e-06 145 3.145e-05 128 Neighborhood of PPP1CA www.broad.mit.e...
Broad MORF_SKP1A View Gene Set 9.873e-06 175 3.268e-05 129 Neighborhood of SKP1A www.broad.mit.e...
Broad MORF_AP2M1 View Gene Set 1.303e-05 197 4.26e-05 130 Neighborhood of AP2M1 www.broad.mit.e...
Broad GNF2_UBE2I View Gene Set 1.307e-05 33 4.26e-05 130 Neighborhood of UBE2I www.broad.mit.e...
Broad MORF_MTA1 View Gene Set 1.511e-05 95 4.886e-05 132 Neighborhood of MTA1 www.broad.mit.e...
Broad MORF_FANCG View Gene Set 1.594e-05 148 5.116e-05 133 Neighborhood of FANCG www.broad.mit.e...
Broad GCM_DFFA View Gene Set 1.666e-05 100 5.308e-05 134 Neighborhood of DFFA www.broad.mit.e...
Broad MORF_TPT1 View Gene Set 1.989e-05 100 6.292e-05 135 Neighborhood of TPT1 www.broad.mit.e...
Broad MORF_TERF2IP View Gene Set 3.168e-05 99 9.947e-05 136 Neighborhood of TERF2IP www.broad.mit.e...
Broad GCM_MYST2 View Gene Set 3.55e-05 138 0.0001106 137 Neighborhood of MYST2 www.broad.mit.e...
Broad MORF_BMI1 View Gene Set 3.796e-05 71 0.0001175 138 Neighborhood of BMI1 www.broad.mit.e...
Broad GCM_RAD21 View Gene Set 4.23e-05 30 0.0001299 139 Neighborhood of RAD21 www.broad.mit.e...
Broad GNF2_SMC1L1 View Gene Set 5.428e-05 24 0.0001655 140 Neighborhood of SMC1L1 www.broad.mit.e...
Broad MORF_SS18 View Gene Set 7.383e-05 55 0.0002236 141 Neighborhood of SS18 www.broad.mit.e...
Broad GCM_PFN1 View Gene Set 7.911e-05 47 0.0002379 142 Neighborhood of PFN1 www.broad.mit.e...
Broad MORF_RFC1 View Gene Set 0.0004193 98 0.001252 143 Neighborhood of RFC1 www.broad.mit.e...
Broad MORF_EIF4E View Gene Set 0.000425 76 0.00126 144 Neighborhood of EIF4E www.broad.mit.e...
Broad MORF_AP3D1 View Gene Set 0.0005244 119 0.001544 145 Neighborhood of AP3D1 www.broad.mit.e...
Broad GCM_TPT1 View Gene Set 0.0005587 69 0.001634 146 Neighborhood of TPT1 www.broad.mit.e...
Broad GCM_SMARCC1 View Gene Set 0.000664 33 0.001929 147 Neighborhood of SMARCC1 www.broad.mit.e...
Broad GCM_MAX View Gene Set 0.0009268 28 0.002674 148 Neighborhood of MAX www.broad.mit.e...
Broad MORF_RAD23B View Gene Set 0.001463 159 0.004192 149 Neighborhood of RAD23B www.broad.mit.e...
Broad MORF_JUND View Gene Set 0.001604 63 0.004566 150 Neighborhood of JUND www.broad.mit.e...
Broad GCM_AIP View Gene Set 0.001998 36 0.00565 151 Neighborhood of AIP www.broad.mit.e...
Broad GCM_DENR View Gene Set 0.002042 40 0.005735 152 Neighborhood of DENR www.broad.mit.e...
Broad GCM_NF2 View Gene Set 0.002185 235 0.006099 153 Neighborhood of NF2 www.broad.mit.e...
Broad GCM_PPM1D View Gene Set 0.00221 22 0.006128 154 Neighborhood of PPM1D www.broad.mit.e...
Broad GCM_MLL View Gene Set 0.002229 130 0.006142 155 Neighborhood of MLL www.broad.mit.e...
Broad MORF_IKBKG View Gene Set 0.002372 119 0.006492 156 Neighborhood of IKBKG www.broad.mit.e...
Broad MORF_FDXR View Gene Set 0.003229 205 0.008782 157 Neighborhood of FDXR www.broad.mit.e...
Broad GCM_TPR View Gene Set 0.00352 29 0.009513 158 Neighborhood of TPR www.broad.mit.e...
Broad MORF_ORC1L View Gene Set 0.003799 61 0.01015 159 Neighborhood of ORC1L www.broad.mit.e...
Broad GCM_FANCC View Gene Set 0.003805 120 0.01015 159 Neighborhood of FANCC www.broad.mit.e...
Broad GCM_RBM8A View Gene Set 0.004032 64 0.01069 161 Neighborhood of RBM8A www.broad.mit.e...
Broad MORF_TPR View Gene Set 0.004115 131 0.01085 162 Neighborhood of TPR www.broad.mit.e...
Broad MORF_REV3L View Gene Set 0.004466 52 0.0117 163 Neighborhood of REV3L www.broad.mit.e...
Broad GCM_PRKCG View Gene Set 0.005059 60 0.01317 164 Neighborhood of PRKCG www.broad.mit.e...
Broad GCM_UBE2N View Gene Set 0.005167 125 0.01337 165 Neighborhood of UBE2N www.broad.mit.e...
Broad MORF_SP3 View Gene Set 0.005406 69 0.0139 166 Neighborhood of SP3 www.broad.mit.e...
Broad GNF2_GLTSCR2 View Gene Set 0.005511 31 0.01409 167 Neighborhood of GLTSCR2 www.broad.mit.e...
Broad MORF_PTEN View Gene Set 0.006361 80 0.01617 168 Neighborhood of PTEN www.broad.mit.e...
Broad MORF_PPP5C View Gene Set 0.00984 81 0.02486 169 Neighborhood of PPP5C www.broad.mit.e...
Broad GCM_CASP2 View Gene Set 0.01024 21 0.02572 170 Neighborhood of CASP2 www.broad.mit.e...
Broad GCM_HBP1 View Gene Set 0.01064 54 0.02658 171 Neighborhood of HBP1 www.broad.mit.e...
Broad MORF_HEAB View Gene Set 0.01089 71 0.02704 172 Neighborhood of HEAB www.broad.mit.e...
Broad MORF_RBBP8 View Gene Set 0.01148 190 0.02834 173 Neighborhood of RBBP8 www.broad.mit.e...
Broad GCM_RING1 View Gene Set 0.01171 106 0.02874 174 Neighborhood of RING1 www.broad.mit.e...
Broad GCM_ZNF198 View Gene Set 0.0123 98 0.03002 175 Neighborhood of ZNF198 www.broad.mit.e...
Broad MORF_DDX11 View Gene Set 0.01355 138 0.03286 176 Neighborhood of DDX11 www.broad.mit.e...
Broad MORF_RFC5 View Gene Set 0.01398 69 0.03373 177 Neighborhood of RFC5 www.broad.mit.e...
Broad MORF_BECN1 View Gene Set 0.01412 93 0.03387 178 Neighborhood of BECN1 www.broad.mit.e...
Broad GCM_CSNK1A1 View Gene Set 0.01644 28 0.03923 179 Neighborhood of CSNK1A1 www.broad.mit.e...
Broad GCM_HDAC1 View Gene Set 0.01823 30 0.04325 180 Neighborhood of HDAC1 www.broad.mit.e...

Gene Set Collection: Broad.c4.CM

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad module_54 View Gene Set 1.085e-27 242 4.928e-25 1 Genes in module_54 www.broad.mit.e...
Broad module_198 View Gene Set 5.361e-21 288 1.217e-18 2 Genes in module_198 www.broad.mit.e...
Broad module_252 View Gene Set 2.66e-19 224 4.025e-17 3 Genes in module_252 www.broad.mit.e...
Broad module_98 View Gene Set 1.991e-18 375 2.26e-16 4 Genes in module_98 www.broad.mit.e...
Broad module_17 View Gene Set 5.711e-18 351 5.185e-16 5 Genes in module_17 www.broad.mit.e...
Broad module_32 View Gene Set 7.115e-18 227 5.384e-16 6 Genes in module_32 www.broad.mit.e...
Broad module_244 View Gene Set 7.229e-13 182 4.689e-11 7 Genes in module_244 www.broad.mit.e...
Broad module_183 View Gene Set 2.856e-10 52 1.621e-08 8 Genes in module_183 www.broad.mit.e...
Broad module_126 View Gene Set 4.369e-10 173 2.204e-08 9 Genes in module_126 www.broad.mit.e...
Broad module_57 View Gene Set 2.872e-09 54 1.304e-07 10 Genes in module_57 www.broad.mit.e...
Broad module_124 View Gene Set 1.35e-08 92 5.573e-07 11 Genes in module_124 www.broad.mit.e...
Broad module_158 View Gene Set 2.267e-08 41 7.983e-07 12 Genes in module_158 www.broad.mit.e...
Broad module_403 View Gene Set 2.286e-08 44 7.983e-07 12 Genes in module_403 www.broad.mit.e...
Broad module_91 View Gene Set 3.252e-08 37 1.055e-06 14 Genes in module_91 www.broad.mit.e...
Broad module_3 View Gene Set 4.929e-08 374 1.399e-06 15 Genes in module_3 www.broad.mit.e...
Broad module_397 View Gene Set 4.782e-08 114 1.399e-06 15 Genes in module_397 www.broad.mit.e...
Broad module_125 View Gene Set 7.308e-08 42 1.952e-06 17 Genes in module_125 www.broad.mit.e...
Broad module_28 View Gene Set 8.487e-08 32 2.141e-06 18 Genes in module_28 www.broad.mit.e...
Broad module_337 View Gene Set 1.081e-07 59 2.583e-06 19 Genes in module_337 www.broad.mit.e...
Broad module_115 View Gene Set 2.285e-07 27 5.187e-06 20 Genes in module_115 www.broad.mit.e...
Broad module_61 View Gene Set 6.363e-07 50 1.376e-05 21 Genes in module_61 www.broad.mit.e...
Broad module_278 View Gene Set 1.25e-06 34 2.58e-05 22 Genes in module_278 www.broad.mit.e...
Broad module_219 View Gene Set 1.316e-06 26 2.597e-05 23 Genes in module_219 www.broad.mit.e...
Broad module_392 View Gene Set 1.428e-06 18 2.701e-05 24 Genes in module_392 www.broad.mit.e...
Broad module_315 View Gene Set 1.862e-06 15 3.382e-05 25 Genes in module_315 www.broad.mit.e...
Broad module_197 View Gene Set 1.971e-06 170 3.442e-05 26 Genes in module_197 www.broad.mit.e...
Broad module_18 View Gene Set 2.379e-06 434 4e-05 27 Genes in module_18 www.broad.mit.e...
Broad module_35 View Gene Set 3.45e-06 16 5.595e-05 28 Genes in module_35 www.broad.mit.e...
Broad module_352 View Gene Set 4.916e-06 17 7.696e-05 29 Genes in module_352 www.broad.mit.e...
Broad module_110 View Gene Set 7.972e-06 15 0.0001206 30 Genes in module_110 www.broad.mit.e...
Broad module_451 View Gene Set 8.767e-06 29 0.0001284 31 Genes in module_451 www.broad.mit.e...
Broad module_102 View Gene Set 1.365e-05 18 0.0001878 32 Genes in module_102 www.broad.mit.e...
Broad module_133 View Gene Set 1.358e-05 15 0.0001878 32 Genes in module_133 www.broad.mit.e...
Broad module_160 View Gene Set 1.426e-05 15 0.0001904 34 Genes in module_160 www.broad.mit.e...
Broad module_127 View Gene Set 1.578e-05 26 0.000199 35 Genes in module_127 www.broad.mit.e...
Broad module_189 View Gene Set 1.567e-05 23 0.000199 35 Genes in module_189 www.broad.mit.e...
Broad module_81 View Gene Set 2.133e-05 20 0.0002617 37 Genes in module_81 www.broad.mit.e...
Broad module_320 View Gene Set 2.502e-05 19 0.0002989 38 Genes in module_320 www.broad.mit.e...
Broad module_149 View Gene Set 3.084e-05 36 0.0003591 39 Genes in module_149 www.broad.mit.e...
Broad module_83 View Gene Set 3.502e-05 296 0.0003975 40 Genes in module_83 www.broad.mit.e...
Broad module_552 View Gene Set 9.119e-05 18 0.00101 41 Genes in module_552 www.broad.mit.e...
Broad module_388 View Gene Set 0.0001496 17 0.001617 42 Genes in module_388 www.broad.mit.e...
Broad module_16 View Gene Set 0.0001586 495 0.001675 43 Genes in module_16 www.broad.mit.e...
Broad module_90 View Gene Set 0.0001654 17 0.001706 44 Genes in module_90 www.broad.mit.e...
Broad module_457 View Gene Set 0.000189 9 0.001907 45 Genes in module_457 www.broad.mit.e...
Broad module_421 View Gene Set 0.0002462 23 0.00243 46 Genes in module_421 www.broad.mit.e...
Broad module_203 View Gene Set 0.000341 16 0.003294 47 Genes in module_203 www.broad.mit.e...
Broad module_159 View Gene Set 0.0003625 81 0.003428 48 Genes in module_159 www.broad.mit.e...
Broad module_50 View Gene Set 0.0003803 13 0.003524 49 Genes in module_50 www.broad.mit.e...
Broad module_204 View Gene Set 0.0006182 82 0.005613 50 Genes in module_204 www.broad.mit.e...
Broad module_168 View Gene Set 0.0006765 22 0.006022 51 Genes in module_168 www.broad.mit.e...
Broad module_222 View Gene Set 0.0007002 22 0.006113 52 Genes in module_222 www.broad.mit.e...
Broad module_355 View Gene Set 0.001089 28 0.009327 53 Genes in module_355 www.broad.mit.e...
Broad module_432 View Gene Set 0.0012 15 0.01009 54 Genes in module_432 www.broad.mit.e...
Broad module_53 View Gene Set 0.001252 389 0.01034 55 Genes in module_53 www.broad.mit.e...
Broad module_299 View Gene Set 0.001587 33 0.01287 56 Genes in module_299 www.broad.mit.e...
Broad module_89 View Gene Set 0.002285 14 0.0182 57 Genes in module_89 www.broad.mit.e...
Broad module_155 View Gene Set 0.002943 25 0.02294 58 Genes in module_155 www.broad.mit.e...
Broad module_538 View Gene Set 0.002981 8 0.02294 58 Genes in module_538 www.broad.mit.e...
Broad module_8 View Gene Set 0.003249 403 0.02426 60 Genes in module_8 www.broad.mit.e...
Broad module_233 View Gene Set 0.00326 22 0.02426 60 Genes in module_233 www.broad.mit.e...
Broad module_534 View Gene Set 0.003766 15 0.02758 62 Genes in module_534 www.broad.mit.e...
Broad module_528 View Gene Set 0.004252 10 0.03064 63 Genes in module_528 www.broad.mit.e...
Broad module_450 View Gene Set 0.006049 9 0.04291 64 Genes in module_450 www.broad.mit.e...
Broad module_56 View Gene Set 0.006568 12 0.0455 65 Genes in module_56 www.broad.mit.e...
Broad module_447 View Gene Set 0.006614 35 0.0455 65 Genes in module_447 www.broad.mit.e...

Gene Set Collection: Broad.c5.BP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 2.288e-25 1197 1.888e-22 1 Genes annotated by the GO term GO:0006139. The chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad RNA_METABOLIC_PROCESS View Gene Set 2.151e-20 801 8.874e-18 2 Genes annotated by the GO term GO:0016070. The chemical reactions and pathways involving RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. www.broad.mit.e...
Broad RNA_PROCESSING View Gene Set 6.001e-20 147 1.65e-17 3 Genes annotated by the GO term GO:0006396. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. www.broad.mit.e...
Broad BIOPOLYMER_METABOLIC_PROCESS View Gene Set 4.421e-15 1623 9.118e-13 4 Genes annotated by the GO term GO:0043283. The chemical reactions and pathways involving biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. www.broad.mit.e...
Broad CELL_CYCLE_PROCESS View Gene Set 1.383e-14 187 2.283e-12 5 Genes annotated by the GO term GO:0022402. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. www.broad.mit.e...
Broad M_PHASE View Gene Set 1.192e-12 111 1.64e-10 6 Genes annotated by the GO term GO:0000279. Progression through M phase the part of the cell cycle comprising nuclear division. www.broad.mit.e...
Broad RNA_SPLICING View Gene Set 4.262e-12 73 5.023e-10 7 Genes annotated by the GO term GO:0008380. The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. www.broad.mit.e...
Broad CELL_CYCLE_PHASE View Gene Set 2.407e-11 167 2.482e-09 8 Genes annotated by the GO term GO:0022403. A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. www.broad.mit.e...
Broad M_PHASE_OF_MITOTIC_CELL_CYCLE View Gene Set 9.966e-11 83 9.136e-09 9 Genes annotated by the GO term GO:0000087. Progression through M phase the part of the mitotic cell cycle during which mitosis takes place. www.broad.mit.e...
Broad MITOSIS View Gene Set 2.904e-10 81 2.396e-08 10 Genes annotated by the GO term GO:0007067. Progression through mitosis the division of the eukaryotic cell nucleus to produce two daughter nuclei that usually contain the identical chromosome complement to their mother. www.broad.mit.e...
Broad MRNA_PROCESSING_GO_0006397 View Gene Set 3.323e-10 59 2.492e-08 11 Genes annotated by the GO term GO:0006397. Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. www.broad.mit.e...
Broad MITOTIC_CELL_CYCLE View Gene Set 6.434e-10 148 3.792e-08 12 Genes annotated by the GO term GO:0000278. Progression through the phases of the mitotic cell cycle the most common eukaryotic cell cycle which canonically comprises four successive phases called G1 S G2 and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division or G1 and G2 phases may be absent. www.broad.mit.e...
Broad CELL_CYCLE_GO_0007049 View Gene Set 6.061e-10 304 3.792e-08 12 Genes annotated by the GO term GO:0007049. The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. www.broad.mit.e...
Broad MRNA_METABOLIC_PROCESS View Gene Set 5.718e-10 70 3.792e-08 12 Genes annotated by the GO term GO:0016071. The chemical reactions and pathways involving mRNA messenger RNA which is responsible for carrying the coded genetic 'message' transcribed from DNA to sites of protein assembly at the ribosomes. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY View Gene Set 2.83e-09 74 1.557e-07 15 Genes annotated by the GO term GO:0022613. The cellular process by which a complex containing RNA and proteins is synthesized aggregates and bonds together. www.broad.mit.e...
Broad TRANSCRIPTION View Gene Set 6.309e-09 738 3.253e-07 16 Genes annotated by the GO term GO:0006350. The synthesis of either RNA on a template of DNA or DNA on a template of RNA. www.broad.mit.e...
Broad TRANSCRIPTION_DNA_DEPENDENT View Gene Set 1.336e-08 623 6.482e-07 17 Genes annotated by the GO term GO:0006351. The synthesis of RNA on a template of DNA. www.broad.mit.e...
Broad RNA_BIOSYNTHETIC_PROCESS View Gene Set 1.932e-08 625 8.857e-07 18 Genes annotated by the GO term GO:0032774. The chemical reactions and pathways resulting in the formation of RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. www.broad.mit.e...
Broad TRANSLATION View Gene Set 7.881e-08 177 3.422e-06 19 Genes annotated by the GO term GO:0006412. The chemical reactions and pathways resulting in the formation of a protein. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. www.broad.mit.e...
Broad DNA_METABOLIC_PROCESS View Gene Set 2.155e-07 253 8.891e-06 20 Genes annotated by the GO term GO:0006259. The chemical reactions and pathways involving DNA deoxyribonucleic acid one of the two main types of nucleic acid consisting of a long unbranched macromolecule formed from one or more commonly two strands of linked deoxyribonucleotides. www.broad.mit.e...
Broad PROTEIN_RNA_COMPLEX_ASSEMBLY View Gene Set 6.652e-07 59 2.613e-05 21 Genes annotated by the GO term GO:0022618. The aggregation arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. www.broad.mit.e...
Broad TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 3.352e-06 449 0.0001257 22 Genes annotated by the GO term GO:0006366. The synthesis of RNA from a DNA template by RNA polymerase II (Pol II) originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX_ASSEMBLY View Gene Set 3.945e-06 271 0.0001308 23 Genes annotated by the GO term GO:0065003. The aggregation arrangement and bonding together of a set of macromolecules to form a complex. www.broad.mit.e...
Broad REGULATION_OF_GENE_EXPRESSION View Gene Set 3.964e-06 660 0.0001308 23 Genes annotated by the GO term GO:0010468. Any process that modulates the frequency rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. www.broad.mit.e...
Broad CHROMOSOME_ORGANIZATION_AND_BIOGENESIS View Gene Set 3.858e-06 117 0.0001308 23 Genes annotated by the GO term GO:0051276. A process that is carried out at the cellular level that results in the formation arrangement of constituent parts or disassembly of chromosomes structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. www.broad.mit.e...
Broad REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 7.099e-06 601 0.0002253 26 Genes annotated by the GO term GO:0019219. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad RIBOSOME_BIOGENESIS_AND_ASSEMBLY View Gene Set 7.69e-06 14 0.000235 27 Genes annotated by the GO term GO:0042254. The process of the formation of the constituents of the ribosome subunits their assembly and their transport to the sites of protein synthesis. www.broad.mit.e...
Broad SPINDLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 1.739e-05 10 0.0005123 28 Genes annotated by the GO term GO:0007051. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the spindle the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. www.broad.mit.e...
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_TRANSPORT View Gene Set 2.155e-05 31 0.0005927 29 Genes annotated by the GO term GO:0015931. The directed movement of nucleobases nucleosides nucleotides and nucleic acids into out of within or between cells. www.broad.mit.e...
Broad CELLULAR_COMPONENT_ASSEMBLY View Gene Set 2.135e-05 288 0.0005927 29 Genes annotated by the GO term GO:0022607. A cellular process that results in the assembly of a part of the cell. www.broad.mit.e...
Broad DNA_REPLICATION View Gene Set 2.235e-05 101 0.0005949 31 Genes annotated by the GO term GO:0006260. The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. www.broad.mit.e...
Broad RRNA_METABOLIC_PROCESS View Gene Set 2.384e-05 12 0.0006146 32 Genes annotated by the GO term GO:0016072. The chemical reactions and pathways involving rRNA ribosomal RNA a structural constituent of ribosomes. www.broad.mit.e...
Broad REGULATION_OF_CELLULAR_METABOLIC_PROCESS View Gene Set 2.946e-05 767 0.0007348 33 Genes annotated by the GO term GO:0031323. Any process that modulates the frequency rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. www.broad.mit.e...
Broad RRNA_PROCESSING View Gene Set 3.1e-05 11 0.0007348 33 Genes annotated by the GO term GO:0006364. Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. www.broad.mit.e...
Broad REGULATION_OF_METABOLIC_PROCESS View Gene Set 3.117e-05 779 0.0007348 33 Genes annotated by the GO term GO:0019222. Any process that modulates the frequency rate or extent of the chemical reactions and pathways within a cell or an organism. www.broad.mit.e...
Broad RNA_SPLICINGVIA_TRANSESTERIFICATION_REACTIONS View Gene Set 3.338e-05 27 0.000765 36 Genes annotated by the GO term GO:0000375. Splicing of RNA via a series of two transesterification reactions. www.broad.mit.e...
Broad MITOTIC_SPINDLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 4.194e-05 9 0.0009353 37 Genes annotated by the GO term GO:0007052. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the microtubule spindle during a mitotic cell cycle. www.broad.mit.e...
Broad CELLULAR_BIOSYNTHETIC_PROCESS View Gene Set 4.843e-05 311 0.001052 38 Genes annotated by the GO term GO:0044249. The chemical reactions and pathways resulting in the formation of substances carried out by individual cells. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTION View Gene Set 6.685e-05 555 0.001414 39 Genes annotated by the GO term GO:0045449. Any process that modulates the frequency rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. www.broad.mit.e...
Broad DNA_REPAIR View Gene Set 8.65e-05 123 0.001784 40 Genes annotated by the GO term GO:0006281. The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations chemical mutagens fungal and bacterial toxins etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal base excision repair nucleotide excision repair photoreactivation bypass double-strand break repair pathway and mismatch repair pathway. www.broad.mit.e...
Broad SISTER_CHROMATID_SEGREGATION View Gene Set 9.884e-05 17 0.001989 41 Genes annotated by the GO term GO:0000819. The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets. www.broad.mit.e...
Broad RESPONSE_TO_ENDOGENOUS_STIMULUS View Gene Set 0.0001019 197 0.002001 42 Genes annotated by the GO term GO:0009719. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of an endogenous stimulus. www.broad.mit.e...
Broad CELL_CYCLE_CHECKPOINT_GO_0000075 View Gene Set 0.0001088 47 0.002087 43 Genes annotated by the GO term GO:0000075. A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. www.broad.mit.e...
Broad NUCLEOCYTOPLASMIC_TRANSPORT View Gene Set 0.000114 83 0.002138 44 Genes annotated by the GO term GO:0006913. The directed movement of molecules between the nucleus and the cytoplasm. www.broad.mit.e...
Broad RESPONSE_TO_DNA_DAMAGE_STIMULUS View Gene Set 0.0001355 159 0.002484 45 Genes annotated by the GO term GO:0006974. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. www.broad.mit.e...
Broad NUCLEAR_TRANSPORT View Gene Set 0.0001923 84 0.003449 46 Genes annotated by the GO term GO:0051169. The directed movement of substances into out of or within the nucleus. www.broad.mit.e...
Broad MITOTIC_SISTER_CHROMATID_SEGREGATION View Gene Set 0.0002 16 0.003511 47 Genes annotated by the GO term GO:0000070. The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome composed of two sister chromatids aligns at the cell equator paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. www.broad.mit.e...
Broad RNA_EXPORT_FROM_NUCLEUS View Gene Set 0.0002112 20 0.003556 48 Genes annotated by the GO term GO:0006405. The directed movement of RNA from the nucleus to the cytoplasm. www.broad.mit.e...
Broad REGULATION_OF_RNA_METABOLIC_PROCESS View Gene Set 0.0002104 457 0.003556 48 Genes annotated by the GO term GO:0051252. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving RNA. www.broad.mit.e...
Broad TRANSLATIONAL_INITIATION View Gene Set 0.0002458 39 0.004005 50 Genes annotated by the GO term GO:0006413. The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome mRNA and an initiation complex that contains the first aminoacyl-tRNA. www.broad.mit.e...
Broad MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0002524 34 0.004005 50 Genes annotated by the GO term GO:0000226. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT View Gene Set 0.0002511 452 0.004005 50 Genes annotated by the GO term GO:0006355. Any process that modulates the frequency rate or extent of DNA-dependent transcription. www.broad.mit.e...
Broad NUCLEAR_EXPORT View Gene Set 0.0002795 31 0.004351 53 Genes annotated by the GO term GO:0051168. The directed movement of substances out of the nucleus. www.broad.mit.e...
Broad TRNA_METABOLIC_PROCESS View Gene Set 0.0003789 18 0.005788 54 Genes annotated by the GO term GO:0006399. The chemical reactions and pathways involving tRNA transfer RNA a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases the function of which has not been completely established. www.broad.mit.e...
Broad REGULATION_OF_MITOSIS View Gene Set 0.0004029 40 0.006043 55 Genes annotated by the GO term GO:0007088. Any process that modulates the frequency rate or extent of mitosis. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 0.0005688 285 0.008379 56 Genes annotated by the GO term GO:0006357. Any process that modulates the frequency rate or extent of transcription from an RNA polymerase II promoter. www.broad.mit.e...
Broad DNA_RECOMBINATION View Gene Set 0.0006739 47 0.009754 57 Genes annotated by the GO term GO:0006310. The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment intrachromosomal recombination or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation conjugation transduction or F-duction. www.broad.mit.e...
Broad MEIOTIC_CELL_CYCLE View Gene Set 0.0009036 34 0.01285 58 Genes annotated by the GO term GO:0051321. Progression through the phases of the meiotic cell cycle in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell. www.broad.mit.e...
Broad ORGANELLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.001155 458 0.01615 59 Genes annotated by the GO term GO:0006996. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of any organelle within a cell. www.broad.mit.e...
Broad BASE_EXCISION_REPAIR View Gene Set 0.001326 16 0.01823 60 Genes annotated by the GO term GO:0006284. In base excision repair an altered base is removed by a DNA glycosylase enzyme followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. www.broad.mit.e...
Broad MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.001513 16 0.02046 61 Genes annotated by the GO term GO:0031023. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a microtubule organizing center a structure from which microtubules grow. www.broad.mit.e...
Broad DNA_INTEGRITY_CHECKPOINT View Gene Set 0.001617 23 0.02152 62 Genes annotated by the GO term GO:0031570. Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure. www.broad.mit.e...
Broad CHROMOSOME_SEGREGATION View Gene Set 0.001701 31 0.02227 63 Genes annotated by the GO term GO:0007059. The process by which genetic material in the form of chromosomes is organized and then physically separated and apportioned to two or more sets. www.broad.mit.e...
Broad NLS_BEARING_SUBSTRATE_IMPORT_INTO_NUCLEUS View Gene Set 0.00178 12 0.02295 64 Genes annotated by the GO term GO:0006607. The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus across the nuclear membrane. www.broad.mit.e...
Broad HISTONE_MODIFICATION View Gene Set 0.00185 22 0.02348 65 Genes annotated by the GO term GO:0016570. The covalent alteration of one or more amino acid residues within a histone protein. www.broad.mit.e...
Broad PROTEIN_DNA_COMPLEX_ASSEMBLY View Gene Set 0.002006 48 0.02508 66 Genes annotated by the GO term GO:0065004. The aggregation arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex. www.broad.mit.e...
Broad DNA_REPLICATION_INITIATION View Gene Set 0.002127 15 0.02619 67 Genes annotated by the GO term GO:0006270. The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix the recruitment of DNA polymerases and the initiation of polymerase action. www.broad.mit.e...
Broad CELL_DIVISION View Gene Set 0.00251 21 0.03045 68 Genes annotated by the GO term GO:0051301. The processes resulting in the physical partitioning and separation of a cell into daughter cells. www.broad.mit.e...
Broad TRANSCRIPTION_INITIATION View Gene Set 0.002569 35 0.03072 69 Genes annotated by the GO term GO:0006352. Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter. www.broad.mit.e...
Broad ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CHROMATIN_ARCHITECTURE View Gene Set 0.002705 72 0.03188 70 Genes annotated by the GO term GO:0006325. The specification formation and maintenance of the physical structure of eukaryotic chromatin. www.broad.mit.e...
Broad COVALENT_CHROMATIN_MODIFICATION View Gene Set 0.003357 23 0.039 71 Genes annotated by the GO term GO:0016569. The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups. www.broad.mit.e...
Broad MEIOSIS_I View Gene Set 0.003435 19 0.03936 72 Genes annotated by the GO term GO:0007127. Progression through the first phase of meiosis in which cells divide and homologous chromosomes are paired and segregated from each other producing two daughter cells. www.broad.mit.e...
Broad REGULATION_OF_TRANSLATIONAL_INITIATION View Gene Set 0.003749 31 0.04236 73 Genes annotated by the GO term GO:0006446. Any process that modulates the frequency rate or extent of translational initiation. www.broad.mit.e...
Broad TRNA_PROCESSING View Gene Set 0.003974 10 0.04431 74 Genes annotated by the GO term GO:0008033. The process by which a pre-tRNA molecule is converted to a mature tRNA ready for addition of an aminoacyl group. www.broad.mit.e...
Broad ANDROGEN_RECEPTOR_SIGNALING_PATHWAY View Gene Set 0.00419 12 0.04608 75 Genes annotated by the GO term GO:0030521. Any series of molecular signals generated as a consequence of an androgen binding to its receptor. www.broad.mit.e...
Broad CENTROSOME_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.004554 15 0.04943 76 Genes annotated by the GO term GO:0051297. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a centrosome a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. www.broad.mit.e...

Gene Set Collection: Broad.c5.CC

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad NUCLEUS View Gene Set 3.313e-39 1353 7.72e-37 1 Genes annotated by the GO term GO:0005634. A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells the nucleus contains all of the cell's chromosomes except the organellar chromosomes and is the site of RNA synthesis and processing. In some species or in specialized cell types RNA metabolism or DNA replication may be absent. www.broad.mit.e...
Broad NUCLEAR_PART View Gene Set 1.102e-31 543 1.284e-29 2 Genes annotated by the GO term GO:0044428. Any constituent part of the nucleus a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. www.broad.mit.e...
Broad NUCLEAR_LUMEN View Gene Set 2.672e-17 365 2.075e-15 3 Genes annotated by the GO term GO:0031981. The volume enclosed by the nuclear inner membrane. www.broad.mit.e...
Broad INTRACELLULAR_ORGANELLE_PART View Gene Set 1.064e-15 1144 6.201e-14 4 Genes annotated by the GO term GO:0044446. A constituent part of an intracellular organelle an organized structure of distinctive morphology and function occurring within the cell. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad ORGANELLE_PART View Gene Set 2.747e-15 1149 9.145e-14 5 Genes annotated by the GO term GO:0044422. Any constituent part of an organelle an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad ORGANELLE_LUMEN View Gene Set 2.393e-15 434 9.145e-14 5 Genes annotated by the GO term GO:0043233. The volume enclosed by the membranes of a particular organelle e.g. endoplasmic reticulum lumen or the space between the two lipid bilayers of a double membrane surrounding an organelle e.g. nuclear membrane lumen. www.broad.mit.e...
Broad MEMBRANE_ENCLOSED_LUMEN View Gene Set 2.393e-15 434 9.145e-14 5 Genes annotated by the GO term GO:0031974. The enclosed volume within a sealed membrane or between two sealed membranes. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX View Gene Set 1.806e-14 129 5.26e-13 8 Genes annotated by the GO term GO:0030529. A macromolecular complex containing both protein and RNA molecules. www.broad.mit.e...
Broad NUCLEOLUS View Gene Set 4.478e-12 116 1.159e-10 9 Genes annotated by the GO term GO:0005730. A small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA the processing of this RNA into 5.8S 18S and 28S components of ribosomal RNA and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX View Gene Set 1.118e-11 914 2.605e-10 10 Genes annotated by the GO term GO:0032991. A stable assembly of two or more macromolecules i.e. proteins nucleic acids carbohydrates or lipids in which the constituent parts function together. www.broad.mit.e...
Broad NON_MEMBRANE_BOUND_ORGANELLE View Gene Set 1.378e-11 613 2.675e-10 11 Genes annotated by the GO term GO:0043228. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane. Includes ribosomes the cytoskeleton and chromosomes. www.broad.mit.e...
Broad INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE View Gene Set 1.378e-11 613 2.675e-10 11 Genes annotated by the GO term GO:0043232. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes the cytoskeleton and chromosomes. www.broad.mit.e...
Broad CHROMOSOME View Gene Set 3.533e-10 122 6.332e-09 13 Genes annotated by the GO term GO:0005694. A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. www.broad.mit.e...
Broad CHROMOSOMAL_PART View Gene Set 1.388e-09 95 2.31e-08 14 Genes annotated by the GO term GO:0044427. Any constituent part of a chromosome a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. www.broad.mit.e...
Broad NUCLEOPLASM View Gene Set 7.119e-09 266 1.106e-07 15 Genes annotated by the GO term GO:0005654. That part of the nuclear content other than the chromosomes or the nucleolus. www.broad.mit.e...
Broad SPLICEOSOME View Gene Set 1.51e-08 44 2.199e-07 16 Genes annotated by the GO term GO:0005681. A ribonucleoprotein complex containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron. www.broad.mit.e...
Broad PORE_COMPLEX View Gene Set 4.6e-07 34 6.305e-06 17 Genes annotated by the GO term GO:0046930. Any small opening in a membrane that allows the passage of gases and/or liquids. www.broad.mit.e...
Broad NUCLEAR_PORE View Gene Set 5.533e-07 29 7.163e-06 18 Genes annotated by the GO term GO:0005643. Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell where the inner and outer nuclear membranes are joined. www.broad.mit.e...
Broad NUCLEOPLASM_PART View Gene Set 6.196e-07 202 7.598e-06 19 Genes annotated by the GO term GO:0044451. Any constituent part of the nucleoplasm that part of the nuclear content other than the chromosomes or the nucleolus. www.broad.mit.e...
Broad SPINDLE View Gene Set 1.471e-06 37 1.713e-05 20 Genes annotated by the GO term GO:0005819. The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE_PART View Gene Set 2.068e-06 40 2.295e-05 21 Genes annotated by the GO term GO:0044453. Any constituent part of the nuclear membrane the envelope that surrounds the nucleus of eukaryotic cells. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE View Gene Set 3.033e-06 48 3.212e-05 22 Genes annotated by the GO term GO:0031965. Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. www.broad.mit.e...
Broad PROTEIN_COMPLEX View Gene Set 3.654e-06 799 3.702e-05 23 Genes annotated by the GO term GO:0043234. Any protein group composed of two or more subunits which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. www.broad.mit.e...
Broad NUCLEOLAR_PART View Gene Set 4.842e-06 16 4.701e-05 24 Genes annotated by the GO term GO:0044452. Any constituent part of a nucleolus a small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. www.broad.mit.e...
Broad NUCLEAR_ENVELOPE View Gene Set 6.489e-06 71 6.047e-05 25 Genes annotated by the GO term GO:0005635. The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space a gap of width 20-40 nm (also called the perinuclear space). www.broad.mit.e...
Broad PROTEASOME_COMPLEX View Gene Set 7.824e-06 23 7.011e-05 26 Genes annotated by the GO term GO:0000502. A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. www.broad.mit.e...
Broad CHROMOSOMEPERICENTRIC_REGION View Gene Set 9.524e-06 31 8.219e-05 27 Genes annotated by the GO term GO:0000775. The central region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes this region corresponds to a single area of the chromosome whereas in holocentric chromosomes it is evenly distributed along the chromosome. www.broad.mit.e...
Broad NUCLEAR_CHROMOSOME View Gene Set 1.038e-05 53 8.638e-05 28 Genes annotated by the GO term GO:0000228. A chromosome found in the nucleus of a eukaryotic cell. www.broad.mit.e...
Broad CONDENSED_CHROMOSOME View Gene Set 1.591e-05 32 0.0001278 29 Genes annotated by the GO term GO:0000793. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. www.broad.mit.e...
Broad CONDENSED_NUCLEAR_CHROMOSOME View Gene Set 1.952e-05 17 0.0001516 30 Genes annotated by the GO term GO:0000794. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure that remains in the nucleus. www.broad.mit.e...
Broad SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX View Gene Set 2.466e-05 20 0.0001853 31 Genes annotated by the GO term GO:0030532. A complex composed of RNA of the small nuclear RNA (snRNA) class and protein found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain e.g. U1 snRNP or U4/U6 snRNP. Many but not all of these complexes are involved in splicing of nuclear mRNAs. www.broad.mit.e...
Broad ENVELOPE View Gene Set 8.344e-05 165 0.0005891 32 Genes annotated by the GO term GO:0031975. A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers and may include a cell wall layer also includes the space between layers. www.broad.mit.e...
Broad ORGANELLE_ENVELOPE View Gene Set 8.344e-05 165 0.0005891 32 Genes annotated by the GO term GO:0031967. A double membrane structure enclosing an organelle including two lipid bilayers and the region between them. In some cases an organelle envelope may have more than two membranes. www.broad.mit.e...
Broad KINETOCHORE View Gene Set 9.44e-05 25 0.0006469 34 Genes annotated by the GO term GO:0000776. A multisubunit complex that is located at the pericentric region of DNA and provides an attachment point for the spindle microtubules. www.broad.mit.e...
Broad NUCLEAR_CHROMOSOME_PART View Gene Set 0.0002742 33 0.001825 35 Genes annotated by the GO term GO:0044454. Any constituent part of a nuclear chromosome a chromosome found in the nucleus of a eukaryotic cell. www.broad.mit.e...
Broad SPINDLE_MICROTUBULE View Gene Set 0.0003884 15 0.002514 36 Genes annotated by the GO term GO:0005876. Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. www.broad.mit.e...
Broad EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX View Gene Set 0.0004413 10 0.002779 37 Genes annotated by the GO term GO:0005852. A complex of several polypeptides that plays at least two important roles in protein synthesis: First eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. www.broad.mit.e...
Broad HETEROGENEOUS_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX View Gene Set 0.0004715 9 0.002891 38 Genes annotated by the GO term GO:0030530. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II that which is translated into protein) with protein which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA. www.broad.mit.e...
Broad MICROTUBULE_ORGANIZING_CENTER View Gene Set 0.000561 64 0.003352 39 Genes annotated by the GO term GO:0005815. A region in a eukaryotic cell such as a centrosome or basal body from which microtubules grow. www.broad.mit.e...
Broad CENTROSOME View Gene Set 0.0008938 55 0.005206 40 Genes annotated by the GO term GO:0005813. A structure comprised of a core structure (in most organisms a pair of centrioles) and peripheral material from which a microtubule-based structure such as a spindle apparatus is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells though in animal cells it changes continually during the cell-division cycle. www.broad.mit.e...
Broad SPINDLE_POLE View Gene Set 0.0009487 17 0.005391 41 Genes annotated by the GO term GO:0000922. Either of the ends of a spindle where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules spindle microtubules and astral microtubules. www.broad.mit.e...
Broad MICROTUBULE View Gene Set 0.002249 31 0.01248 42 Genes annotated by the GO term GO:0005874. Any of the long generally straight hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation e.g. in the spindle. www.broad.mit.e...
Broad TRANSCRIPTION_FACTOR_COMPLEX View Gene Set 0.002392 84 0.01296 43 Genes annotated by the GO term GO:0005667. Any complex distinct from RNA polymerase including one or more polypeptides capable of binding DNA at promoters or at cis-acting regulatory sequences and regulating transcription. www.broad.mit.e...
Broad ORGANELLAR_RIBOSOME View Gene Set 0.00259 22 0.01341 44 Genes annotated by the GO term GO:0000313. A ribosome contained within a subcellular organelle. www.broad.mit.e...
Broad MITOCHONDRIAL_RIBOSOME View Gene Set 0.00259 22 0.01341 44 Genes annotated by the GO term GO:0005761. A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. www.broad.mit.e...
Broad RIBOSOMAL_SUBUNIT View Gene Set 0.002778 20 0.01407 46 Genes annotated by the GO term GO:0033279. Either of the two ribonucleoprotein complexes that associate to form a ribosome. www.broad.mit.e...
Broad CHROMATIN View Gene Set 0.003953 35 0.0196 47 Genes annotated by the GO term GO:0000785. The ordered and organized complex of DNA and protein that forms the chromosome. www.broad.mit.e...
Broad RIBOSOME View Gene Set 0.004417 39 0.02144 48 Genes annotated by the GO term GO:0005840. An intracellular organelle about 200 A in diameter consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits one large and one small each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients expressed in Svedberg units (symbol: S). Hence the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes eukaryotes mitochondria and chloroplasts have characteristically distinct ribosomal proteins. www.broad.mit.e...
Broad REPLICATION_FORK View Gene Set 0.005765 18 0.02741 49 Genes annotated by the GO term GO:0005657. The Y-shaped region of a replicating DNA molecule resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. www.broad.mit.e...
Broad ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.006612 11 0.02796 50 Genes annotated by the GO term GO:0000314. The smaller of the two subunits of an organellar ribosome. www.broad.mit.e...
Broad MITOCHONDRIAL_SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.006612 11 0.02796 50 Genes annotated by the GO term GO:0005763. The smaller of the two subunits of a mitochondrial ribosome. www.broad.mit.e...
Broad MEDIATOR_COMPLEX View Gene Set 0.006206 18 0.02796 50 Genes annotated by the GO term GO:0000119. A protein complex that enables the RNA polymerase II-general RNA polymerase II transcription factor complex to react to transcriptional activator proteins; also enhances the level of basal transcription. www.broad.mit.e...
Broad CELL_CORTEX_PART View Gene Set 0.006144 24 0.02796 50 Genes annotated by the GO term GO:0044448. Any constituent part of the cell cortex the region of a cell that lies just beneath the plasma membrane and often but not always contains a network of actin filaments and associated proteins. www.broad.mit.e...
Broad CELL_CORTEX View Gene Set 0.006277 38 0.02796 50 Genes annotated by the GO term GO:0005938. The region of a cell that lies just beneath the plasma membrane and often but not always contains a network of actin filaments and associated proteins. www.broad.mit.e...
Broad NUCLEAR_CHROMATIN View Gene Set 0.00672 14 0.02796 50 Genes annotated by the GO term GO:0000790. The ordered and organized complex of DNA and protein that forms the chromosome in the nucleus. www.broad.mit.e...
Broad SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.006612 11 0.02796 50 Genes annotated by the GO term GO:0015935. The smaller of the two subunits of a ribosome. www.broad.mit.e...
Broad CYTOSKELETAL_PART View Gene Set 0.009343 231 0.03819 57 Genes annotated by the GO term GO:0044430. Any constituent part of the cytoskeleton a cellular scaffolding or skeleton that maintains cell shape enables some cell motion (using structures such as flagella and cilia) and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments microfilaments microtubules and the microtrabecular lattice. www.broad.mit.e...
Broad CORTICAL_CYTOSKELETON View Gene Set 0.009824 20 0.03946 58 Genes annotated by the GO term GO:0030863. The portion of the cytoskeleton that lies just beneath the plasma membrane. www.broad.mit.e...

Gene Set Collection: Broad.c5.MF

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad RNA_BINDING View Gene Set 6.001e-19 236 2.376e-16 1 Genes annotated by the GO term GO:0003723. Interacting selectively with an RNA molecule or a portion thereof. www.broad.mit.e...
Broad TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING View Gene Set 2.557e-09 39 3.376e-07 2 Genes annotated by the GO term GO:0008135. Functions during translation by binding nucleic acids during polypeptide synthesis at the ribosome. www.broad.mit.e...
Broad DNA_BINDING View Gene Set 2.439e-09 587 3.376e-07 2 Genes annotated by the GO term GO:0003677. Interacting selectively with DNA (deoxyribonucleic acid). www.broad.mit.e...
Broad TRANSLATION_REGULATOR_ACTIVITY View Gene Set 1.213e-08 41 1.201e-06 4 Genes annotated by the GO term GO:0045182. Any substance involved in the initiation activation perpetuation repression or termination of polypeptide synthesis at the ribosome. www.broad.mit.e...
Broad TRANSLATION_INITIATION_FACTOR_ACTIVITY View Gene Set 4.971e-08 24 3.937e-06 5 Genes annotated by the GO term GO:0003743. Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. www.broad.mit.e...
Broad HELICASE_ACTIVITY View Gene Set 1.441e-06 49 9.508e-05 6 Genes annotated by the GO term GO:0004386. Catalysis of the unwinding of a DNA or RNA duplex. www.broad.mit.e...
Broad ATP_DEPENDENT_HELICASE_ACTIVITY View Gene Set 2.533e-06 26 0.0001433 7 Genes annotated by the GO term GO:0008026. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the unwinding of a DNA or RNA helix. www.broad.mit.e...
Broad RNA_HELICASE_ACTIVITY View Gene Set 1.329e-05 24 0.0006581 8 Genes annotated by the GO term GO:0003724. Catalysis of the unwinding of an RNA helix. www.broad.mit.e...
Broad RNA_SPLICING_FACTOR_ACTIVITYTRANSESTERIFICATION_MECHANISM View Gene Set 1.653e-05 14 0.0007273 9 Genes annotated by the GO term GO:0031202. An activity which binds RNA and functions to assist splicing of substrate RNA(s) by facilitating the formation and stabilization of a catalytic conformation in which the splice junctions of the RNA(s) to be spliced are positioned for a transesterification reaction that occurs between two sites within the RNA(s) to be spliced. www.broad.mit.e...
Broad SINGLE_STRANDED_DNA_BINDING View Gene Set 1.899e-05 34 0.0007518 10 Genes annotated by the GO term GO:0003697. Interacting selectively with single-stranded DNA. www.broad.mit.e...
Broad STRUCTURE_SPECIFIC_DNA_BINDING View Gene Set 2.115e-05 55 0.0007615 11 Genes annotated by the GO term GO:0043566. Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. www.broad.mit.e...
Broad RNA_DEPENDENT_ATPASE_ACTIVITY View Gene Set 2.678e-05 18 0.0008838 12 Genes annotated by the GO term GO:0008186. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of RNA; drives another reaction. www.broad.mit.e...
Broad STRUCTURAL_CONSTITUENT_OF_RIBOSOME View Gene Set 3.379e-05 80 0.001029 13 Genes annotated by the GO term GO:0003735. The action of a molecule that contributes to the structural integrity of the ribosome. www.broad.mit.e...
Broad DNA_DEPENDENT_ATPASE_ACTIVITY View Gene Set 4.223e-05 22 0.001195 14 Genes annotated by the GO term GO:0008094. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single- or double-stranded DNA; drives another reaction. www.broad.mit.e...
Broad ATP_DEPENDENT_RNA_HELICASE_ACTIVITY View Gene Set 4.536e-05 17 0.001197 15 Genes annotated by the GO term GO:0004004. Catalysis of the reaction: ATP + H2O = ADP + phosphate driving the unwinding of an RNA helix. www.broad.mit.e...
Broad DNA_HELICASE_ACTIVITY View Gene Set 8.783e-05 24 0.002174 16 Genes annotated by the GO term GO:0003678. Catalysis of the unwinding of a DNA duplex. www.broad.mit.e...
Broad CHROMATIN_BINDING View Gene Set 0.0001195 32 0.002783 17 Genes annotated by the GO term GO:0003682. Interacting selectively with chromatin the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. www.broad.mit.e...
Broad UNFOLDED_PROTEIN_BINDING View Gene Set 0.0001659 41 0.00365 18 Genes annotated by the GO term GO:0051082. Interacting selectively with an unfolded protein. www.broad.mit.e...
Broad DOUBLE_STRANDED_DNA_BINDING View Gene Set 0.0001755 32 0.003657 19 Genes annotated by the GO term GO:0003690. Interacting selectively with double-stranded DNA. www.broad.mit.e...
Broad LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS View Gene Set 0.0002812 14 0.005568 20 Genes annotated by the GO term GO:0016875. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. www.broad.mit.e...
Broad MRNA_BINDING View Gene Set 0.0005359 22 0.01011 21 Genes annotated by the GO term GO:0003729. Interacting selectively with pre-messenger RNA (pre-mRNA) or messenger RNA (mRNA). www.broad.mit.e...
Broad RIBONUCLEASE_ACTIVITY View Gene Set 0.0006511 25 0.01172 22 Genes annotated by the GO term GO:0004540. Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. www.broad.mit.e...
Broad ATP_DEPENDENT_DNA_HELICASE_ACTIVITY View Gene Set 0.001218 11 0.02097 23 Genes annotated by the GO term GO:0004003. Catalysis of the reaction: ATP + H2O = ADP + phosphate driving the unwinding of the DNA helix. www.broad.mit.e...
Broad TRANSCRIPTION_ACTIVATOR_ACTIVITY View Gene Set 0.001726 169 0.02847 24 Genes annotated by the GO term GO:0016563. Any transcription regulator activity required for initiation or upregulation of transcription. www.broad.mit.e...
Broad ENDONUCLEASE_ACTIVITY_GO_0016893 View Gene Set 0.001857 11 0.02941 25 Genes annotated by the GO term GO:0016893. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. www.broad.mit.e...
Broad LIGASE_ACTIVITY_FORMING_CARBON_NITROGEN_BONDS View Gene Set 0.00238 68 0.0325 26 Genes annotated by the GO term GO:0016879. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. www.broad.mit.e...
Broad TRANSCRIPTION_FACTOR_ACTIVITY View Gene Set 0.00236 340 0.0325 26 Genes annotated by the GO term GO:0003700. The function of binding to a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. www.broad.mit.e...
Broad TRANSCRIPTION_FACTOR_BINDING View Gene Set 0.00217 300 0.0325 26 Genes annotated by the GO term GO:0008134. Interacting selectively with a transcription factor any protein required to initiate or regulate transcription. www.broad.mit.e...
Broad HORMONE_RECEPTOR_BINDING View Gene Set 0.002267 29 0.0325 26 Genes annotated by the GO term GO:0051427. Interacting selectively with a receptor for hormones. www.broad.mit.e...
Broad TRANSCRIPTION_COFACTOR_ACTIVITY View Gene Set 0.003178 222 0.04195 30 Genes annotated by the GO term GO:0003712. The function that links a sequence-specific transcription factor to the core RNA polymerase II complex but does not bind DNA itself. www.broad.mit.e...
Broad ENDORIBONUCLEASE_ACTIVITY View Gene Set 0.00346 13 0.0442 31 Genes annotated by the GO term GO:0004521. Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. www.broad.mit.e...
Broad NUCLEASE_ACTIVITY View Gene Set 0.003679 54 0.04553 32 Genes annotated by the GO term GO:0004518. Catalysis of the hydrolysis of ester linkages within nucleic acids. www.broad.mit.e...
Broad RNA_POLYMERASE_II_TRANSCRIPTION_MEDIATOR_ACTIVITY View Gene Set 0.003852 13 0.04623 33 Genes annotated by the GO term GO:0016455. Functions to mediate the interaction of transcriptional activators with the RNA polymerase II-general RNA polymerase II transcription factor complex. www.broad.mit.e...

Gene Set Collection: PMID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
PMID 15635413 View Gene Set 1.507e-56 421 3.777e-53 1 Nucleolar proteome dynamics. www.ncbi.nlm.ni...
PMID 12429849 View Gene Set 1.434e-35 106 1.798e-32 2 Functional proteomic analysis of human nucleolus. www.ncbi.nlm.ni...
PMID 15302935 View Gene Set 5.583e-35 773 4.666e-32 3 Large-scale characterization of HeLa cell nuclear phosphoproteins. www.ncbi.nlm.ni...
PMID 17643375 View Gene Set 4.034e-33 391 2.528e-30 4 Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. www.ncbi.nlm.ni...
PMID 16565220 View Gene Set 2.346e-32 210 1.176e-29 5 Phosphoproteome analysis of the human mitotic spindle. www.ncbi.nlm.ni...
PMID 11790298 View Gene Set 5.828e-32 208 2.435e-29 6 Directed proteomic analysis of the human nucleolus. www.ncbi.nlm.ni...
PMID 16964243 View Gene Set 2.717e-29 504 9.732e-27 7 A probability-based approach for high-throughput protein phosphorylation analysis and site localization. www.ncbi.nlm.ni...
PMID 12226669 View Gene Set 7.682e-23 108 2.407e-20 8 Comprehensive proteomic analysis of the human spliceosome. www.ncbi.nlm.ni...
PMID 11991638 View Gene Set 3.011e-16 74 8.387e-14 9 Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. www.ncbi.nlm.ni...
PMID 15592455 View Gene Set 4.928e-16 317 1.235e-13 10 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. www.ncbi.nlm.ni...
PMID 14559993 View Gene Set 1.299e-14 51 2.96e-12 11 Regulation of alternative splicing by SRrp86 and its interacting proteins. www.ncbi.nlm.ni...
PMID 20085707 View Gene Set 1.649e-11 42 3.445e-09 12 Aire's partners in the molecular control of immunological tolerance. www.ncbi.nlm.ni...
PMID 16916647 View Gene Set 3.463e-11 76 6.677e-09 13 Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. www.ncbi.nlm.ni...
PMID 15231747 View Gene Set 5.902e-11 212 1.057e-08 14 A protein interaction framework for human mRNA degradation. www.ncbi.nlm.ni...
PMID 12706105 View Gene Set 3.255e-10 182 5.44e-08 15 Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. www.ncbi.nlm.ni...
PMID 11285280 View Gene Set 6.356e-10 62 9.959e-08 16 Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. www.ncbi.nlm.ni...
PMID 12171929 View Gene Set 1.54e-09 31 2.16e-07 17 A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. www.ncbi.nlm.ni...
PMID 20508983 View Gene Set 1.551e-09 102 2.16e-07 17 Centrosome-related genes genetic variation and risk of breast cancer. www.ncbi.nlm.ni...
PMID 15782174 View Gene Set 2.302e-09 31 3.038e-07 19 Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. www.ncbi.nlm.ni...
PMID 12791267 View Gene Set 5.705e-09 50 7.152e-07 20 Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. www.ncbi.nlm.ni...
PMID 18162579 View Gene Set 6.148e-09 22 7.339e-07 21 Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. www.ncbi.nlm.ni...
PMID 15009096 View Gene Set 1.781e-08 39 2.029e-06 22 Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex while BMI-1 is transiently co-localized with the centromeric region in interphase. www.ncbi.nlm.ni...
PMID 14743216 View Gene Set 2.511e-08 132 2.737e-06 23 A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. www.ncbi.nlm.ni...
PMID 16319397 View Gene Set 2.769e-08 20 2.893e-06 24 Characterization of histone H2A and H2B variants and their post-translational modifications by mass spectrometry. www.ncbi.nlm.ni...
PMID 10893419 View Gene Set 3.795e-08 41 3.113e-06 25 Degradation of HIV-1 integrase by the N-end rule pathway. www.ncbi.nlm.ni...
PMID 12419264 View Gene Set 3.795e-08 41 3.113e-06 25 The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing. www.ncbi.nlm.ni...
PMID 12791985 View Gene Set 3.925e-08 37 3.113e-06 25 Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. www.ncbi.nlm.ni...
PMID 12859895 View Gene Set 3.973e-08 47 3.113e-06 25 Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. www.ncbi.nlm.ni...
PMID 14550573 View Gene Set 3.795e-08 41 3.113e-06 25 Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits. www.ncbi.nlm.ni...
PMID 17289661 View Gene Set 3.903e-08 35 3.113e-06 25 Molecular composition of IMP1 ribonucleoprotein granules. www.ncbi.nlm.ni...
PMID 9079628 View Gene Set 3.795e-08 41 3.113e-06 25 HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation. www.ncbi.nlm.ni...
PMID 9731529 View Gene Set 3.95e-08 24 3.113e-06 25 Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. www.ncbi.nlm.ni...
PMID 15029244 View Gene Set 4.941e-08 57 3.754e-06 33 Mammalian Cdh1/Fzr mediates its own degradation. www.ncbi.nlm.ni...
PMID 15146077 View Gene Set 7.019e-08 32 5.175e-06 34 The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. www.ncbi.nlm.ni...
PMID 8811196 View Gene Set 8.049e-08 37 5.766e-06 35 Structure and functions of the 20S and 26S proteasomes. www.ncbi.nlm.ni...
PMID 12719574 View Gene Set 1.099e-07 42 6.26e-06 36 Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions. www.ncbi.nlm.ni...
PMID 12750511 View Gene Set 1.099e-07 42 6.26e-06 36 Hypermutation of HIV-1 DNA in the absence of the Vif protein. www.ncbi.nlm.ni...
PMID 12830140 View Gene Set 1.099e-07 42 6.26e-06 36 DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses. www.ncbi.nlm.ni...
PMID 12840737 View Gene Set 1.099e-07 42 6.26e-06 36 Good to CU. www.ncbi.nlm.ni...
PMID 12914693 View Gene Set 1.099e-07 42 6.26e-06 36 Death by deamination: a novel host restriction system for HIV-1. www.ncbi.nlm.ni...
PMID 12920286 View Gene Set 1.099e-07 42 6.26e-06 36 Virology. Weapons of mutational destruction. www.ncbi.nlm.ni...
PMID 14614829 View Gene Set 1.099e-07 42 6.26e-06 36 The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G. www.ncbi.nlm.ni...
PMID 9811770 View Gene Set 1.099e-07 42 6.26e-06 36 An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein. www.ncbi.nlm.ni...
PMID 9846577 View Gene Set 1.099e-07 42 6.26e-06 36 Evidence for a newly discovered cellular anti-HIV-1 phenotype. www.ncbi.nlm.ni...
PMID 12045100 View Gene Set 1.504e-07 18 8.376e-06 45 DNA replication in eukaryotic cells. www.ncbi.nlm.ni...
PMID 12167863 View Gene Set 2.085e-07 43 9.503e-06 46 Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. www.ncbi.nlm.ni...
PMID 12588972 View Gene Set 1.837e-07 56 9.503e-06 46 Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region. www.ncbi.nlm.ni...
PMID 12808465 View Gene Set 2.085e-07 43 9.503e-06 46 The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. www.ncbi.nlm.ni...
PMID 12808466 View Gene Set 2.085e-07 43 9.503e-06 46 Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. www.ncbi.nlm.ni...
PMID 12809610 View Gene Set 2.085e-07 43 9.503e-06 46 DNA deamination mediates innate immunity to retroviral infection. www.ncbi.nlm.ni...
PMID 12970355 View Gene Set 2.085e-07 43 9.503e-06 46 The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity. www.ncbi.nlm.ni...
PMID 14527406 View Gene Set 2.085e-07 43 9.503e-06 46 HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. www.ncbi.nlm.ni...
PMID 14528300 View Gene Set 2.085e-07 43 9.503e-06 46 The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. www.ncbi.nlm.ni...
PMID 14528301 View Gene Set 2.085e-07 43 9.503e-06 46 HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. www.ncbi.nlm.ni...
PMID 14557625 View Gene Set 2.085e-07 43 9.503e-06 46 The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15) a cellular inhibitor of virus infectivity. www.ncbi.nlm.ni...
PMID 11095689 View Gene Set 2.68e-07 17 1.2e-05 56 The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase. www.ncbi.nlm.ni...
PMID 16713563 View Gene Set 4.105e-07 19 1.805e-05 57 Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. www.ncbi.nlm.ni...
PMID 11543634 View Gene Set 4.22e-07 58 1.824e-05 58 The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. www.ncbi.nlm.ni...
PMID 14564014 View Gene Set 5.03e-07 47 2.137e-05 59 Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. www.ncbi.nlm.ni...
PMID 17363900 View Gene Set 5.126e-07 14 2.142e-05 60 The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. www.ncbi.nlm.ni...
PMID 12234937 View Gene Set 5.791e-07 34 2.38e-05 61 Characterization of novel SF3b and 17S U2 snRNP proteins including a human Prp5p homologue and an SF3b DEAD-box protein. www.ncbi.nlm.ni...
PMID 14657027 View Gene Set 6.589e-07 74 2.664e-05 62 Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. www.ncbi.nlm.ni...
PMID 19710015 View Gene Set 8.739e-07 48 3.478e-05 63 The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor. www.ncbi.nlm.ni...
PMID 19237606 View Gene Set 9.629e-07 84 3.772e-05 64 Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. www.ncbi.nlm.ni...
PMID 16283522 View Gene Set 9.886e-07 18 3.813e-05 65 Inhibition of core histones acetylation by carcinogenic nickel(II). www.ncbi.nlm.ni...
PMID 16627869 View Gene Set 2.243e-06 17 8.522e-05 66 Quantitative proteomic analysis of post-translational modifications of human histones. www.ncbi.nlm.ni...
PMID 16236267 View Gene Set 2.383e-06 77 8.919e-05 67 Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. www.ncbi.nlm.ni...
PMID 15707391 View Gene Set 2.888e-06 23 0.0001065 68 DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. www.ncbi.nlm.ni...
PMID 11101529 View Gene Set 3.167e-06 34 0.0001151 69 Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. www.ncbi.nlm.ni...
PMID 15324660 View Gene Set 3.456e-06 242 0.0001238 70 Proteomic functional and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. www.ncbi.nlm.ni...
PMID 10436018 View Gene Set 3.557e-06 15 0.0001256 71 The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells. www.ncbi.nlm.ni...
PMID 15226314 View Gene Set 3.679e-06 20 0.0001281 72 Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. www.ncbi.nlm.ni...
PMID 12930902 View Gene Set 3.852e-06 11 0.0001305 73 The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. www.ncbi.nlm.ni...
PMID 14983052 View Gene Set 3.825e-06 391 0.0001305 73 The human olfactory receptor gene family. www.ncbi.nlm.ni...
PMID 9566873 View Gene Set 4.076e-06 74 0.0001362 75 Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. www.ncbi.nlm.ni...
PMID 20496165 View Gene Set 4.625e-06 68 0.0001526 76 Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. www.ncbi.nlm.ni...
PMID 16307923 View Gene Set 4.714e-06 23 0.0001535 77 Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. www.ncbi.nlm.ni...
PMID 18270339 View Gene Set 6.261e-06 57 0.0002012 78 Comprehensive analysis of DNA repair gene variants and risk of meningioma. www.ncbi.nlm.ni...
PMID 15130578 View Gene Set 6.796e-06 22 0.0002157 79 Why do cells need an assembly machine for RNA-protein complexes? www.ncbi.nlm.ni...
PMID 11080476 View Gene Set 8.185e-06 87 0.0002565 80 Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. www.ncbi.nlm.ni...
PMID 17148452 View Gene Set 8.897e-06 87 0.0002754 81 Characterization of the interactome of the human MutL homologues MLH1 PMS1 and PMS2. www.ncbi.nlm.ni...
PMID 12757711 View Gene Set 9.329e-06 18 0.0002852 82 Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. www.ncbi.nlm.ni...
PMID 11689053 View Gene Set 1.013e-05 70 0.000306 83 Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA. www.ncbi.nlm.ni...
PMID 11279123 View Gene Set 1.445e-05 31 0.0004304 84 The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 15189156 View Gene Set 1.459e-05 88 0.0004304 84 The molecular mechanics of eukaryotic translation. www.ncbi.nlm.ni...
PMID 12614612 View Gene Set 1.482e-05 19 0.000432 86 Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. www.ncbi.nlm.ni...
PMID 14532270 View Gene Set 1.536e-05 12 0.0004404 87 A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. www.ncbi.nlm.ni...
PMID 18809582 View Gene Set 1.546e-05 25 0.0004404 87 Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. www.ncbi.nlm.ni...
PMID 15504738 View Gene Set 1.705e-05 19 0.0004804 89 Genes affecting the cell cycle growth maintenance and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. www.ncbi.nlm.ni...
PMID 18715871 View Gene Set 1.844e-05 20 0.0005138 90 PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4. www.ncbi.nlm.ni...
PMID 16085932 View Gene Set 1.926e-05 18 0.0005307 91 A novel evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. www.ncbi.nlm.ni...
PMID 15232106 View Gene Set 2.082e-05 30 0.0005673 92 Self-assembling protein microarrays. www.ncbi.nlm.ni...
PMID 11829477 View Gene Set 2.359e-05 13 0.000636 93 Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex. www.ncbi.nlm.ni...
PMID 9582194 View Gene Set 2.524e-05 67 0.0006732 94 A map of 75 human ribosomal protein genes. www.ncbi.nlm.ni...
PMID 17220478 View Gene Set 2.829e-05 63 0.0007465 95 Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells. www.ncbi.nlm.ni...
PMID 11719186 View Gene Set 3.103e-05 17 0.0008021 96 AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. www.ncbi.nlm.ni...
PMID 15456888 View Gene Set 3.098e-05 24 0.0008021 96 The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. www.ncbi.nlm.ni...
PMID 11310559 View Gene Set 3.19e-05 17 0.0008161 98 Identification of nuclear-import and cell-cycle regulatory proteins that bind to prothymosin alpha. www.ncbi.nlm.ni...
PMID 12388589 View Gene Set 3.544e-05 17 0.00089 99 A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. www.ncbi.nlm.ni...
PMID 16622419 View Gene Set 3.55e-05 16 0.00089 99 The human CENP-A centromeric nucleosome-associated complex. www.ncbi.nlm.ni...
PMID 16622420 View Gene Set 3.645e-05 14 0.0009047 101 The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. www.ncbi.nlm.ni...
PMID 14667819 View Gene Set 3.705e-05 112 0.0009106 102 Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. www.ncbi.nlm.ni...
PMID 18063578 View Gene Set 4.292e-05 31 0.001045 103 The layered structure of human mitochondrial DNA nucleoids. www.ncbi.nlm.ni...
PMID 20522537 View Gene Set 4.458e-05 73 0.001075 104 Variation within DNA repair pathway genes and risk of multiple sclerosis. www.ncbi.nlm.ni...
PMID 12228227 View Gene Set 5.831e-05 30 0.001392 105 Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1. www.ncbi.nlm.ni...
PMID 12962325 View Gene Set 5.962e-05 22 0.00141 106 Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. www.ncbi.nlm.ni...
PMID 11714285 View Gene Set 7.642e-05 11 0.001696 107 The appended C-domain of human methionyl-tRNA synthetase has a tRNA-sequestering function. www.ncbi.nlm.ni...
PMID 16055448 View Gene Set 7.642e-05 11 0.001696 107 The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex. www.ncbi.nlm.ni...
PMID 8052601 View Gene Set 7.642e-05 11 0.001696 107 Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit. www.ncbi.nlm.ni...
PMID 8078941 View Gene Set 7.642e-05 11 0.001696 107 Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer. www.ncbi.nlm.ni...
PMID 8188258 View Gene Set 7.642e-05 11 0.001696 107 The human EPRS locus (formerly the QARS locus): a gene encoding a class I and a class II aminoacyl-tRNA synthetase. www.ncbi.nlm.ni...
PMID 8449960 View Gene Set 7.642e-05 11 0.001696 107 Expression of human aspartyl-tRNA synthetase in Escherichia coli. Functional analysis of the N-terminal putative amphiphilic helix. www.ncbi.nlm.ni...
PMID 9278442 View Gene Set 7.642e-05 11 0.001696 107 Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant. www.ncbi.nlm.ni...
PMID 20226869 View Gene Set 8.462e-05 25 0.001861 114 Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations. www.ncbi.nlm.ni...
PMID 18997788 View Gene Set 8.844e-05 10 0.001928 115 The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction. www.ncbi.nlm.ni...
PMID 12408966 View Gene Set 9.703e-05 76 0.002097 116 The human and mouse replication-dependent histone genes. www.ncbi.nlm.ni...
PMID 14966270 View Gene Set 9.906e-05 19 0.002123 117 Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. www.ncbi.nlm.ni...
PMID 10766737 View Gene Set 0.0001011 11 0.00214 118 Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. www.ncbi.nlm.ni...
PMID 19596235 View Gene Set 0.0001016 85 0.00214 118 Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. www.ncbi.nlm.ni...
PMID 18954305 View Gene Set 0.0001102 13 0.002301 120 Structural basis and specificity of human otubain 1-mediated deubiquitination. www.ncbi.nlm.ni...
PMID 11931757 View Gene Set 0.0001296 22 0.002641 121 Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. www.ncbi.nlm.ni...
PMID 7494303 View Gene Set 0.0001289 12 0.002641 121 Mutational analysis of cell cycle arrest nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr. www.ncbi.nlm.ni...
PMID 9822659 View Gene Set 0.0001289 11 0.002641 121 Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3. www.ncbi.nlm.ni...
PMID 19468067 View Gene Set 0.0001405 10 0.002841 124 Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. www.ncbi.nlm.ni...
PMID 9562972 View Gene Set 0.0001465 11 0.002939 125 HIV-1 nuclear import: matrix protein is back on center stage this time together with Vpr. www.ncbi.nlm.ni...
PMID 11205743 View Gene Set 0.0001496 15 0.002963 126 Polo-like kinase interacts with proteasomes and regulates their activity. www.ncbi.nlm.ni...
PMID 9878398 View Gene Set 0.0001501 13 0.002963 126 Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. www.ncbi.nlm.ni...
PMID 11416179 View Gene Set 0.0001788 12 0.003502 128 All kinesin superfamily protein KIF genes in mouse and human. www.ncbi.nlm.ni...
PMID 11125146 View Gene Set 0.0001847 10 0.003589 129 Inhibition of eukaryotic DNA replication by geminin binding to Cdt1. www.ncbi.nlm.ni...
PMID 19584272 View Gene Set 0.0001902 11 0.003667 130 Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers. www.ncbi.nlm.ni...
PMID 11124703 View Gene Set 0.0001942 18 0.003677 131 Characterization of 16 novel human genes showing high similarity to yeast sequences. www.ncbi.nlm.ni...
PMID 8995409 View Gene Set 0.0001951 11 0.003677 131 Conservation and diversity of eukaryotic translation initiation factor eIF3. www.ncbi.nlm.ni...
PMID 8995410 View Gene Set 0.0001951 10 0.003677 131 The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170. www.ncbi.nlm.ni...
PMID 16716197 View Gene Set 0.0001994 10 0.00373 134 Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. www.ncbi.nlm.ni...
PMID 8722009 View Gene Set 0.000207 80 0.003843 135 Structure and evolution of mammalian ribosomal proteins. www.ncbi.nlm.ni...
PMID 11714716 View Gene Set 0.0002198 13 0.004051 136 Gemin5 a novel WD repeat protein component of the SMN complex that binds Sm proteins. www.ncbi.nlm.ni...
PMID 15461802 View Gene Set 0.000223 293 0.004082 137 A genome annotation-driven approach to cloning the human ORFeome. www.ncbi.nlm.ni...
PMID 15960975 View Gene Set 0.0002316 28 0.004207 138 Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. www.ncbi.nlm.ni...
PMID 10983978 View Gene Set 0.0002458 10 0.004433 139 Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. www.ncbi.nlm.ni...
PMID 8590280 View Gene Set 0.0002541 41 0.004551 140 Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. www.ncbi.nlm.ni...
PMID 11812149 View Gene Set 0.0002639 13 0.004693 141 Protein-protein interactions of hCsl4p with other human exosome subunits. www.ncbi.nlm.ni...
PMID 15502821 View Gene Set 0.0002718 12 0.004798 142 A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. www.ncbi.nlm.ni...
PMID 10601273 View Gene Set 0.0002894 21 0.005073 143 Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein whereas export is due to a nuclear export signal sequence in glucokinase. www.ncbi.nlm.ni...
PMID 14519125 View Gene Set 0.0002926 12 0.005094 144 Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3. www.ncbi.nlm.ni...
PMID 11799066 View Gene Set 0.0003105 21 0.005356 145 Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. www.ncbi.nlm.ni...
PMID 15078818 View Gene Set 0.000314 11 0.005356 145 Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo. www.ncbi.nlm.ni...
PMID 16702407 View Gene Set 0.000314 11 0.005356 145 DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A. www.ncbi.nlm.ni...
PMID 10531003 View Gene Set 0.0003528 15 0.005896 148 Newly assembled snRNPs associate with coiled bodies before speckles suggesting a nuclear snRNP maturation pathway. www.ncbi.nlm.ni...
PMID 17322308 View Gene Set 0.0003514 13 0.005896 148 Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry. www.ncbi.nlm.ni...
PMID 18599441 View Gene Set 0.0003514 13 0.005896 148 Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3. www.ncbi.nlm.ni...
PMID 10608806 View Gene Set 0.0003557 25 0.005906 151 Substrate specificities and identification of putative substrates of ATM kinase family members. www.ncbi.nlm.ni...
PMID 10851237 View Gene Set 0.0003909 11 0.006447 152 Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). www.ncbi.nlm.ni...
PMID 9111189 View Gene Set 0.0003954 16 0.006479 153 Which DNA polymerases are used for DNA-repair in eukaryotes? www.ncbi.nlm.ni...
PMID 11799067 View Gene Set 0.0004167 10 0.006739 154 E2F integrates cell cycle progression with DNA repair replication and G(2)/M checkpoints. www.ncbi.nlm.ni...
PMID 9472028 View Gene Set 0.000416 12 0.006739 154 SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. www.ncbi.nlm.ni...
PMID 16094384 View Gene Set 0.0004236 80 0.006807 156 Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. www.ncbi.nlm.ni...
PMID 11076961 View Gene Set 0.0004302 14 0.006869 157 Characterization of vertebrate cohesin complexes and their regulation in prophase. www.ncbi.nlm.ni...
PMID 11914277 View Gene Set 0.0004562 38 0.007239 158 miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. www.ncbi.nlm.ni...
PMID 16387653 View Gene Set 0.0005245 42 0.008271 159 ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. www.ncbi.nlm.ni...
PMID 9439656 View Gene Set 0.0006036 55 0.009458 160 The human histone gene cluster at the D6S105 locus. www.ncbi.nlm.ni...
PMID 15010469 View Gene Set 0.0006509 15 0.01007 161 Phosphorylation of histone H2A inhibits transcription on chromatin templates. www.ncbi.nlm.ni...
PMID 15196461 View Gene Set 0.0006502 11 0.01007 161 The highly conserved and multifunctional NuA4 HAT complex. www.ncbi.nlm.ni...
PMID 10064132 View Gene Set 0.0006793 14 0.01038 163 The human H2A and H2B histone gene complement. www.ncbi.nlm.ni...
PMID 14733938 View Gene Set 0.000677 13 0.01038 163 Protein-protein interactions among human 20S proteasome subunits and proteassemblin. www.ncbi.nlm.ni...
PMID 10601333 View Gene Set 0.0007092 12 0.01078 165 Gemin3: A novel DEAD box protein that interacts with SMN the spinal muscular atrophy gene product and is a component of gems. www.ncbi.nlm.ni...
PMID 12732143 View Gene Set 0.000721 14 0.01089 166 The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. www.ncbi.nlm.ni...
PMID 1574589 View Gene Set 0.0007446 11 0.01118 167 De novo purine nucleotide biosynthesis. www.ncbi.nlm.ni...
PMID 12221128 View Gene Set 0.0007963 70 0.01188 168 Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex. www.ncbi.nlm.ni...
PMID 11110791 View Gene Set 0.000812 12 0.01205 169 Three novel components of the human exosome. www.ncbi.nlm.ni...
PMID 14615539 View Gene Set 0.0008334 11 0.01229 170 Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI. www.ncbi.nlm.ni...
PMID 18377426 View Gene Set 0.0008446 20 0.01238 171 Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex. www.ncbi.nlm.ni...
PMID 14499622 View Gene Set 0.0008684 53 0.01266 172 Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation cell signaling oxidative metabolism and cellular transport. www.ncbi.nlm.ni...
PMID 11500380 View Gene Set 0.0008808 10 0.01276 173 A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. www.ncbi.nlm.ni...
PMID 12963728 View Gene Set 0.0009036 21 0.01302 174 Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. www.ncbi.nlm.ni...
PMID 12419256 View Gene Set 0.0009471 12 0.01357 175 Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring. www.ncbi.nlm.ni...
PMID 15647280 View Gene Set 0.00096 17 0.01361 176 The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. www.ncbi.nlm.ni...
PMID 17525332 View Gene Set 0.0009665 22 0.01361 176 ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. www.ncbi.nlm.ni...
PMID 17581632 View Gene Set 0.0009719 11 0.01361 176 Reconstitution reveals the functional core of mammalian eIF3. www.ncbi.nlm.ni...
PMID 19138993 View Gene Set 0.0009652 25 0.01361 176 Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. www.ncbi.nlm.ni...
PMID 16359901 View Gene Set 0.001052 14 0.01465 180 Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. www.ncbi.nlm.ni...
PMID 9119399 View Gene Set 0.001065 35 0.01475 181 Human histone gene organization: nonregular arrangement within a large cluster. www.ncbi.nlm.ni...
PMID 10725331 View Gene Set 0.001108 14 0.01527 182 Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. www.ncbi.nlm.ni...
PMID 7811265 View Gene Set 0.00113 16 0.01549 183 Human proteasome subunits from 2-dimensional gels identified by partial sequencing. www.ncbi.nlm.ni...
PMID 11060040 View Gene Set 0.001283 15 0.01749 184 Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. www.ncbi.nlm.ni...
PMID 11551941 View Gene Set 0.001296 26 0.01752 185 The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 7584028 View Gene Set 0.0013 37 0.01752 185 Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). www.ncbi.nlm.ni...
PMID 12837248 View Gene Set 0.001345 22 0.01803 187 The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. www.ncbi.nlm.ni...
PMID 11531413 View Gene Set 0.001406 27 0.01866 188 HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25. www.ncbi.nlm.ni...
PMID 11713266 View Gene Set 0.001404 12 0.01866 188 The methylosome a 20S complex containing JBP1 and pICln produces dimethylarginine-modified Sm proteins. www.ncbi.nlm.ni...
PMID 10783165 View Gene Set 0.001552 12 0.02046 190 BASC a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. www.ncbi.nlm.ni...
PMID 11073998 View Gene Set 0.001559 15 0.02046 190 TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture. www.ncbi.nlm.ni...
PMID 19270065 View Gene Set 0.001622 11 0.02118 192 MRE11 complex links RECQ5 helicase to sites of DNA damage. www.ncbi.nlm.ni...
PMID 19690177 View Gene Set 0.001631 31 0.02118 193 Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk. www.ncbi.nlm.ni...
PMID 18082152 View Gene Set 0.001735 11 0.02242 194 Human CpG binding protein interacts with MLL1 MLL2 and hSet1 and regulates Hox gene expression. www.ncbi.nlm.ni...
PMID 7584026 View Gene Set 0.00189 43 0.0243 195 Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. www.ncbi.nlm.ni...
PMID 17388661 View Gene Set 0.001981 24 0.02534 196 Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen. www.ncbi.nlm.ni...
PMID 1403646 View Gene Set 0.002067 17 0.0262 197 The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC. www.ncbi.nlm.ni...
PMID 16109376 View Gene Set 0.002069 17 0.0262 197 The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. www.ncbi.nlm.ni...
PMID 15823041 View Gene Set 0.002106 13 0.02654 199 Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes. www.ncbi.nlm.ni...
PMID 12213199 View Gene Set 0.002141 216 0.02684 200 DEFOG: a practical scheme for deciphering families of genes. www.ncbi.nlm.ni...

Gene Set Collection: ChromosomalTiles5Mb

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null chr17_77.5-82.5Mb View Gene Set 1.562e-05 54 0.0087 1 Genomic tile: chr17 ; 77500001-82500001 Mb genome.ucsc.edu...
Null chr17_80-85Mb View Gene Set 8.336e-06 37 0.0087 1 Genomic tile: chr17 ; 80000001-85000001 Mb genome.ucsc.edu...
Null chr11_60-65Mb View Gene Set 6.894e-05 104 0.0192 3 Genomic tile: chr11 ; 60000001-65000001 Mb genome.ucsc.edu...
Null chr16_67.5-72.5Mb View Gene Set 6.117e-05 51 0.0192 3 Genomic tile: chr16 ; 67500001-72500001 Mb genome.ucsc.edu...
Null chr11_57.5-62.5Mb View Gene Set 0.0001422 71 0.03169 5 Genomic tile: chr11 ; 57500001-62500001 Mb genome.ucsc.edu...

Gene Set Collection: Prosite

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null PS50102 View Gene Set 1.697e-23 229 1.247e-20 1 RRM expasy.org/pros...
Null PS51195 View Gene Set 3.565e-09 37 1.31e-06 2 Q_MOTIF expasy.org/pros...
Null PS51194 View Gene Set 2.745e-08 113 6.726e-06 3 HELICASE_CTER expasy.org/pros...
Null PS00357 View Gene Set 6.413e-08 19 1.178e-05 4 HISTONE_H2B expasy.org/pros...
Null PS51192 View Gene Set 1.128e-07 112 1.658e-05 5 HELICASE_ATP_BIND_1 expasy.org/pros...
Null PS00039 View Gene Set 7.735e-07 27 9.476e-05 6 DEAD_ATP_HELICASE expasy.org/pros...
Null PS00750 View Gene Set 2.889e-06 9 0.000236 7 TCP1_1 expasy.org/pros...
Null PS00751 View Gene Set 2.889e-06 9 0.000236 7 TCP1_2 expasy.org/pros...
Null PS00995 View Gene Set 2.889e-06 9 0.000236 7 TCP1_3 expasy.org/pros...
Null PS50262 View Gene Set 3.29e-05 765 0.002418 10 G_PROTEIN_RECEP_F1_2 expasy.org/pros...
Null PS50174 View Gene Set 8.04e-05 25 0.004924 11 G_PATCH expasy.org/pros...
Null PS50280 View Gene Set 7.44e-05 47 0.004924 11 SET expasy.org/pros...
Null PS51214 View Gene Set 0.0001276 10 0.007217 13 IBB expasy.org/pros...
Null PS00674 View Gene Set 0.0001961 29 0.01029 14 AAA expasy.org/pros...
Null PS50082 View Gene Set 0.0002644 233 0.01295 15 WD_REPEATS_2 expasy.org/pros...
Null PS50051 View Gene Set 0.0003228 8 0.01456 16 MCM_2 expasy.org/pros...
Null PS50294 View Gene Set 0.0003482 245 0.01456 16 WD_REPEATS_REGION expasy.org/pros...
Null PS50862 View Gene Set 0.0003566 18 0.01456 16 AA_TRNA_LIGASE_II expasy.org/pros...
Null PS00237 View Gene Set 0.0005068 555 0.01961 19 G_PROTEIN_RECEP_F1_1 expasy.org/pros...
Null PS00046 View Gene Set 0.0006327 21 0.02111 20 HISTONE_H2A expasy.org/pros...
Null PS00178 View Gene Set 0.0006605 15 0.02111 20 AA_TRNA_LIGASE_I expasy.org/pros...
Null PS00854 View Gene Set 0.000621 12 0.02111 20 PROTEASOME_B_1 expasy.org/pros...
Null PS50157 View Gene Set 0.0006331 811 0.02111 20 ZINC_FINGER_C2H2_2 expasy.org/pros...
Null PS00028 View Gene Set 0.0009934 830 0.03042 24 ZINC_FINGER_C2H2_1 expasy.org/pros...
Null PS01358 View Gene Set 0.00161 25 0.0424 25 ZF_RANBP2_1 expasy.org/pros...
Null PS50199 View Gene Set 0.00161 23 0.0424 25 ZF_RANBP2_2 expasy.org/pros...
Null PS51038 View Gene Set 0.001615 11 0.0424 25 BAH expasy.org/pros...
Null PS51273 View Gene Set 0.001572 6 0.0424 25 GATASE_TYPE_1 expasy.org/pros...
Null PS00847 View Gene Set 0.001799 6 0.04409 29 MCM_1 expasy.org/pros...
Null PS50128 View Gene Set 0.001785 6 0.04409 29 SURP expasy.org/pros...
Null PS51151 View Gene Set 0.001955 9 0.04635 31 NAC_AB expasy.org/pros...

Gene Set Collection: Enzyme

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null EC:3.6.4.13 View Gene Set 6.568e-05 13 0.01038 1 RNA helicase expasy.org/enzy...
Null EC:3.4.25.1 View Gene Set 0.000505 20 0.0399 2 Proteasome endopeptidase complex expasy.org/enzy...

Gene Set Collection: ppi.BIND

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.E2F1 View Gene Set 4.888e-06 12 0.0009239 1 Protein-protein-interaction for E2F1 www.ncbi.nlm.ni...
Null ppi.E2F4 View Gene Set 6.092e-05 14 0.005472 2 Protein-protein-interaction for E2F4 www.ncbi.nlm.ni...
Null ppi.RAD51 View Gene Set 8.685e-05 7 0.005472 2 Protein-protein-interaction for RAD51 www.ncbi.nlm.ni...
Null ppi.SNORD3A View Gene Set 0.0004236 9 0.01637 4 Protein-protein-interaction for SNORD3A www.ncbi.nlm.ni...
Null ppi.UXT View Gene Set 0.0004332 8 0.01637 4 Protein-protein-interaction for UXT www.ncbi.nlm.ni...
Null ppi.155871 View Gene Set 0.0006416 21 0.02021 6 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.POP1 View Gene Set 0.001258 5 0.02689 7 Protein-protein-interaction for POP1 www.ncbi.nlm.ni...
Null ppi.RIBIN View Gene Set 0.001048 8 0.02689 7 Protein-protein-interaction for RIBIN www.ncbi.nlm.ni...
Null ppi.RBL2 View Gene Set 0.00128 14 0.02689 7 Protein-protein-interaction for RBL2 www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 0.002225 7 0.04204 10 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.POLR2G View Gene Set 0.002565 5 0.04408 11 Protein-protein-interaction for POLR2G www.ncbi.nlm.ni...

Gene Set Collection: ppi.BioGRID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.155871 View Gene Set 2.76e-36 236 6.34e-33 1 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 7.954e-24 147 9.135e-21 2 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.SRRM2 View Gene Set 8.563e-19 101 6.556e-16 3 Protein-protein-interaction for SRRM2 www.ncbi.nlm.ni...
Null ppi.SRRM1 View Gene Set 2.541e-15 64 1.459e-12 4 Protein-protein-interaction for SRRM1 www.ncbi.nlm.ni...
Null ppi.WBP4 View Gene Set 4.025e-11 35 1.849e-08 5 Protein-protein-interaction for WBP4 www.ncbi.nlm.ni...
Null ppi.KHDRBS2 View Gene Set 4.731e-09 46 1.811e-06 6 Protein-protein-interaction for KHDRBS2 www.ncbi.nlm.ni...
Null ppi.CDT1 View Gene Set 1.473e-08 37 4.833e-06 7 Protein-protein-interaction for CDT1 www.ncbi.nlm.ni...
Null ppi.GPN1 View Gene Set 3.79e-08 27 9.164e-06 8 Protein-protein-interaction for GPN1 www.ncbi.nlm.ni...
Null ppi.UCHL5 View Gene Set 3.192e-08 33 9.164e-06 8 Protein-protein-interaction for UCHL5 www.ncbi.nlm.ni...
Null ppi.72462 View Gene Set 3.99e-08 42 9.164e-06 8 Protein-protein-interaction for 72462 www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 5.827e-08 53 1.217e-05 11 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.EIF3F View Gene Set 3.526e-07 22 6.749e-05 12 Protein-protein-interaction for EIF3F www.ncbi.nlm.ni...
Null ppi.RNPS1 View Gene Set 4.622e-07 38 7.79e-05 13 Protein-protein-interaction for RNPS1 www.ncbi.nlm.ni...
Null ppi.PSMD13 View Gene Set 4.748e-07 20 7.79e-05 13 Protein-protein-interaction for PSMD13 www.ncbi.nlm.ni...
Null ppi.USP39 View Gene Set 6.533e-07 15 0.0001 15 Protein-protein-interaction for USP39 www.ncbi.nlm.ni...
Null ppi.HIST1H4A View Gene Set 1.262e-06 28 0.0001812 16 Protein-protein-interaction for HIST1H4A www.ncbi.nlm.ni...
Null ppi.SUMO2 View Gene Set 1.405e-06 50 0.0001898 17 Protein-protein-interaction for SUMO2 www.ncbi.nlm.ni...
Null ppi.PSMD6 View Gene Set 1.834e-06 21 0.000234 18 Protein-protein-interaction for PSMD6 www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 1.971e-06 43 0.0002383 19 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.RUVBL2 View Gene Set 2.457e-06 64 0.0002822 20 Protein-protein-interaction for RUVBL2 www.ncbi.nlm.ni...
Null ppi.RNU12-2P View Gene Set 3.37e-06 18 0.0003518 21 Protein-protein-interaction for RNU12-2P www.ncbi.nlm.ni...
Null ppi.RNU11 View Gene Set 3.37e-06 18 0.0003518 21 Protein-protein-interaction for RNU11 www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 4.768e-06 24 0.0004563 23 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.EIF3H View Gene Set 4.639e-06 16 0.0004563 23 Protein-protein-interaction for EIF3H www.ncbi.nlm.ni...
Null ppi.RRP1B View Gene Set 5.722e-06 21 0.0005258 25 Protein-protein-interaction for RRP1B www.ncbi.nlm.ni...
Null ppi.TP53BP1 View Gene Set 8.534e-06 13 0.0007539 26 Protein-protein-interaction for TP53BP1 www.ncbi.nlm.ni...
Null ppi.GTF3C3 View Gene Set 9.626e-06 11 0.0008189 27 Protein-protein-interaction for GTF3C3 www.ncbi.nlm.ni...
Null ppi.AURKA View Gene Set 1.156e-05 9 0.0009482 28 Protein-protein-interaction for AURKA www.ncbi.nlm.ni...
Null ppi.WWOX View Gene Set 1.343e-05 19 0.001064 29 Protein-protein-interaction for WWOX www.ncbi.nlm.ni...
Null ppi.RPA1 View Gene Set 1.509e-05 23 0.001155 30 Protein-protein-interaction for RPA1 www.ncbi.nlm.ni...
Null ppi.CHTF18 View Gene Set 1.559e-05 13 0.001155 31 Protein-protein-interaction for CHTF18 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 1.613e-05 168 0.001158 32 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 1.869e-05 15 0.001301 33 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.RUVBL1 View Gene Set 2.1e-05 38 0.001419 34 Protein-protein-interaction for RUVBL1 www.ncbi.nlm.ni...
Null ppi.PSMD14 View Gene Set 2.295e-05 16 0.001506 35 Protein-protein-interaction for PSMD14 www.ncbi.nlm.ni...
Null ppi.PRKDC View Gene Set 2.527e-05 38 0.001613 36 Protein-protein-interaction for PRKDC www.ncbi.nlm.ni...
Null ppi.USP14 View Gene Set 3.038e-05 22 0.001886 37 Protein-protein-interaction for USP14 www.ncbi.nlm.ni...
Null ppi.RAD51 View Gene Set 3.345e-05 12 0.002022 38 Protein-protein-interaction for RAD51 www.ncbi.nlm.ni...
Null ppi.USP36 View Gene Set 4.611e-05 17 0.002716 39 Protein-protein-interaction for USP36 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 4.936e-05 12 0.002835 40 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.PRPF19 View Gene Set 6.883e-05 9 0.003856 41 Protein-protein-interaction for PRPF19 www.ncbi.nlm.ni...
Null ppi.PRPF8 View Gene Set 7.415e-05 12 0.004056 42 Protein-protein-interaction for PRPF8 www.ncbi.nlm.ni...
Null ppi.PSMD7 View Gene Set 7.618e-05 12 0.004069 43 Protein-protein-interaction for PSMD7 www.ncbi.nlm.ni...
Null ppi.THAP1 View Gene Set 8.995e-05 11 0.004491 44 Protein-protein-interaction for THAP1 www.ncbi.nlm.ni...
Null ppi.LYAR View Gene Set 8.936e-05 26 0.004491 44 Protein-protein-interaction for LYAR www.ncbi.nlm.ni...
Null ppi.RPAP3 View Gene Set 8.854e-05 29 0.004491 44 Protein-protein-interaction for RPAP3 www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 9.721e-05 9 0.004706 47 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.MLH1 View Gene Set 0.0001003 9 0.004706 47 Protein-protein-interaction for MLH1 www.ncbi.nlm.ni...
Null ppi.SUPT3H View Gene Set 0.0001004 14 0.004706 47 Protein-protein-interaction for SUPT3H www.ncbi.nlm.ni...
Null ppi.EIF3B View Gene Set 0.0001077 10 0.004949 50 Protein-protein-interaction for EIF3B www.ncbi.nlm.ni...
Null ppi.MGMT View Gene Set 0.0001099 28 0.004951 51 Protein-protein-interaction for MGMT www.ncbi.nlm.ni...
Null ppi.HDAC3 View Gene Set 0.0001191 92 0.005259 52 Protein-protein-interaction for HDAC3 www.ncbi.nlm.ni...
Null ppi.SF3B1 View Gene Set 0.0001418 24 0.006147 53 Protein-protein-interaction for SF3B1 www.ncbi.nlm.ni...
Null ppi.PAXIP1 View Gene Set 0.000145 18 0.006169 54 Protein-protein-interaction for PAXIP1 www.ncbi.nlm.ni...
Null ppi.NUP62 View Gene Set 0.0001517 15 0.006338 55 Protein-protein-interaction for NUP62 www.ncbi.nlm.ni...
Null ppi.KAT2A View Gene Set 0.0001561 12 0.006403 56 Protein-protein-interaction for KAT2A www.ncbi.nlm.ni...
Null ppi.SRPK2 View Gene Set 0.0001593 7 0.006418 57 Protein-protein-interaction for SRPK2 www.ncbi.nlm.ni...
Null ppi.CTCF View Gene Set 0.0001646 6 0.006423 58 Protein-protein-interaction for CTCF www.ncbi.nlm.ni...
Null ppi.TERF2 View Gene Set 0.000165 9 0.006423 58 Protein-protein-interaction for TERF2 www.ncbi.nlm.ni...
Null ppi.KLF13 View Gene Set 0.0001703 9 0.006518 60 Protein-protein-interaction for KLF13 www.ncbi.nlm.ni...
Null ppi.KAT2B View Gene Set 0.0001896 71 0.007141 61 Protein-protein-interaction for KAT2B www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 0.0001989 14 0.007367 62 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.PUF60 View Gene Set 0.0002051 31 0.007476 63 Protein-protein-interaction for PUF60 www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 0.0002218 40 0.007802 64 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.GIYD2 View Gene Set 0.0002177 32 0.007802 64 Protein-protein-interaction for GIYD2 www.ncbi.nlm.ni...
Null ppi.WDR77 View Gene Set 0.0002247 15 0.007802 64 Protein-protein-interaction for WDR77 www.ncbi.nlm.ni...
Null ppi.HIST1H3A View Gene Set 0.0002276 30 0.007802 64 Protein-protein-interaction for HIST1H3A www.ncbi.nlm.ni...
Null ppi.MED30 View Gene Set 0.0002437 26 0.008232 68 Protein-protein-interaction for MED30 www.ncbi.nlm.ni...
Null ppi.KPNA6 View Gene Set 0.000251 6 0.008356 69 Protein-protein-interaction for KPNA6 www.ncbi.nlm.ni...
Null ppi.C20orf20 View Gene Set 0.0002629 15 0.008625 70 Protein-protein-interaction for C20orf20 www.ncbi.nlm.ni...
Null ppi.POLR3C View Gene Set 0.0002765 10 0.008626 71 Protein-protein-interaction for POLR3C www.ncbi.nlm.ni...
Null ppi.DDX20 View Gene Set 0.0002779 17 0.008626 71 Protein-protein-interaction for DDX20 www.ncbi.nlm.ni...
Null ppi.GIGYF2 View Gene Set 0.0002705 17 0.008626 71 Protein-protein-interaction for GIGYF2 www.ncbi.nlm.ni...
Null ppi.C16orf53 View Gene Set 0.0002684 9 0.008626 71 Protein-protein-interaction for C16orf53 www.ncbi.nlm.ni...
Null ppi.MRE11A View Gene Set 0.0003071 13 0.00928 75 Protein-protein-interaction for MRE11A www.ncbi.nlm.ni...
Null ppi.DPY30 View Gene Set 0.0003033 9 0.00928 75 Protein-protein-interaction for DPY30 www.ncbi.nlm.ni...
Null ppi.PDS5A View Gene Set 0.0003293 6 0.009823 77 Protein-protein-interaction for PDS5A www.ncbi.nlm.ni...
Null ppi.FANCA View Gene Set 0.0003474 14 0.01006 78 Protein-protein-interaction for FANCA www.ncbi.nlm.ni...
Null ppi.BRF2 View Gene Set 0.0003502 23 0.01006 78 Protein-protein-interaction for BRF2 www.ncbi.nlm.ni...
Null ppi.PAAF1 View Gene Set 0.0003491 20 0.01006 78 Protein-protein-interaction for PAAF1 www.ncbi.nlm.ni...
Null ppi.MCPH1 View Gene Set 0.0003687 17 0.01045 81 Protein-protein-interaction for MCPH1 www.ncbi.nlm.ni...
Null ppi.TAF10 View Gene Set 0.0003841 27 0.01076 82 Protein-protein-interaction for TAF10 www.ncbi.nlm.ni...
Null ppi.WDR48 View Gene Set 0.0003974 52 0.011 83 Protein-protein-interaction for WDR48 www.ncbi.nlm.ni...
Null ppi.SUPT16H View Gene Set 0.0004093 11 0.01119 84 Protein-protein-interaction for SUPT16H www.ncbi.nlm.ni...
Null ppi.TCERG1 View Gene Set 0.0004202 35 0.01136 85 Protein-protein-interaction for TCERG1 www.ncbi.nlm.ni...
Null ppi.PSMD10 View Gene Set 0.0004441 14 0.01173 86 Protein-protein-interaction for PSMD10 www.ncbi.nlm.ni...
Null ppi.USP11 View Gene Set 0.0004392 17 0.01173 86 Protein-protein-interaction for USP11 www.ncbi.nlm.ni...
Null ppi.HIST2H2AC View Gene Set 0.0004561 13 0.0119 88 Protein-protein-interaction for HIST2H2AC www.ncbi.nlm.ni...
Null ppi.FEN1 View Gene Set 0.0004699 11 0.01213 89 Protein-protein-interaction for FEN1 www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 0.0005432 38 0.01386 90 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.PPARGC1A View Gene Set 0.0005667 33 0.01431 91 Protein-protein-interaction for PPARGC1A www.ncbi.nlm.ni...
Null ppi.MCRS1 View Gene Set 0.0006166 16 0.01507 92 Protein-protein-interaction for MCRS1 www.ncbi.nlm.ni...
Null ppi.MPP6 View Gene Set 0.0006106 13 0.01507 92 Protein-protein-interaction for MPP6 www.ncbi.nlm.ni...
Null ppi.EIF3A View Gene Set 0.0006141 12 0.01507 92 Protein-protein-interaction for EIF3A www.ncbi.nlm.ni...
Null ppi.BCL7C View Gene Set 0.0006631 11 0.01603 95 Protein-protein-interaction for BCL7C www.ncbi.nlm.ni...
Null ppi.PPP4R2 View Gene Set 0.0006764 7 0.01603 96 Protein-protein-interaction for PPP4R2 www.ncbi.nlm.ni...
Null ppi.PTCD3 View Gene Set 0.0006911 6 0.01603 96 Protein-protein-interaction for PTCD3 www.ncbi.nlm.ni...
Null ppi.EIF3G View Gene Set 0.0006843 8 0.01603 96 Protein-protein-interaction for EIF3G www.ncbi.nlm.ni...
Null ppi.MED17 View Gene Set 0.0006795 15 0.01603 96 Protein-protein-interaction for MED17 www.ncbi.nlm.ni...
Null ppi.HABP4 View Gene Set 0.0007197 16 0.01653 100 Protein-protein-interaction for HABP4 www.ncbi.nlm.ni...
Null ppi.FANCD2 View Gene Set 0.0007348 6 0.01671 101 Protein-protein-interaction for FANCD2 www.ncbi.nlm.ni...
Null ppi.MDC1 View Gene Set 0.0007437 20 0.01675 102 Protein-protein-interaction for MDC1 www.ncbi.nlm.ni...
Null ppi.CXXC1 View Gene Set 0.0007959 13 0.01763 103 Protein-protein-interaction for CXXC1 www.ncbi.nlm.ni...
Null ppi.SMARCB1 View Gene Set 0.0007982 30 0.01763 103 Protein-protein-interaction for SMARCB1 www.ncbi.nlm.ni...
Null ppi.COPS8 View Gene Set 0.0008073 8 0.01766 105 Protein-protein-interaction for COPS8 www.ncbi.nlm.ni...
Null ppi.HIST2H3C View Gene Set 0.0008543 26 0.01851 106 Protein-protein-interaction for HIST2H3C www.ncbi.nlm.ni...
Null ppi.POLR1E View Gene Set 0.00091 11 0.01954 107 Protein-protein-interaction for POLR1E www.ncbi.nlm.ni...
Null ppi.DMAP1 View Gene Set 0.0009669 13 0.02034 108 Protein-protein-interaction for DMAP1 www.ncbi.nlm.ni...
Null ppi.VIM View Gene Set 0.0009737 36 0.02034 108 Protein-protein-interaction for VIM www.ncbi.nlm.ni...
Null ppi.HIST3H3 View Gene Set 0.0009739 16 0.02034 108 Protein-protein-interaction for HIST3H3 www.ncbi.nlm.ni...
Null ppi.MCM8 View Gene Set 0.000996 6 0.02061 111 Protein-protein-interaction for MCM8 www.ncbi.nlm.ni...
Null ppi.ZNF335 View Gene Set 0.001039 8 0.02131 112 Protein-protein-interaction for ZNF335 www.ncbi.nlm.ni...
Null ppi.CDCA5 View Gene Set 0.001095 6 0.02201 113 Protein-protein-interaction for CDCA5 www.ncbi.nlm.ni...
Null ppi.CBX3 View Gene Set 0.00109 23 0.02201 113 Protein-protein-interaction for CBX3 www.ncbi.nlm.ni...
Null ppi.RFWD2 View Gene Set 0.001102 26 0.02201 113 Protein-protein-interaction for RFWD2 www.ncbi.nlm.ni...
Null ppi.NUP43 View Gene Set 0.001149 6 0.02237 116 Protein-protein-interaction for NUP43 www.ncbi.nlm.ni...
Null ppi.MYST3 View Gene Set 0.001144 9 0.02237 116 Protein-protein-interaction for MYST3 www.ncbi.nlm.ni...
Null ppi.USP42 View Gene Set 0.001131 24 0.02237 116 Protein-protein-interaction for USP42 www.ncbi.nlm.ni...
Null ppi.CD3EAP View Gene Set 0.00117 6 0.02259 119 Protein-protein-interaction for CD3EAP www.ncbi.nlm.ni...
Null ppi.MAML3 View Gene Set 0.001208 10 0.02312 120 Protein-protein-interaction for MAML3 www.ncbi.nlm.ni...
Null ppi.BRIP1 View Gene Set 0.001274 8 0.02418 121 Protein-protein-interaction for BRIP1 www.ncbi.nlm.ni...
Null ppi.ZCCHC10 View Gene Set 0.001303 6 0.02453 122 Protein-protein-interaction for ZCCHC10 www.ncbi.nlm.ni...
Null ppi.EIF3C View Gene Set 0.001323 6 0.0247 123 Protein-protein-interaction for EIF3C www.ncbi.nlm.ni...
Null ppi.FAF2 View Gene Set 0.001363 7 0.02525 124 Protein-protein-interaction for FAF2 www.ncbi.nlm.ni...
Null ppi.HNF1A View Gene Set 0.001381 12 0.02539 125 Protein-protein-interaction for HNF1A www.ncbi.nlm.ni...
Null ppi.RBMX View Gene Set 0.001455 15 0.02652 126 Protein-protein-interaction for RBMX www.ncbi.nlm.ni...
Null ppi.ATXN7 View Gene Set 0.001511 10 0.02733 127 Protein-protein-interaction for ATXN7 www.ncbi.nlm.ni...
Null ppi.RAD54B View Gene Set 0.00153 8 0.02746 128 Protein-protein-interaction for RAD54B www.ncbi.nlm.ni...
Null ppi.GAR1 View Gene Set 0.001553 9 0.02765 129 Protein-protein-interaction for GAR1 www.ncbi.nlm.ni...
Null ppi.G3BP1 View Gene Set 0.001593 18 0.02814 130 Protein-protein-interaction for G3BP1 www.ncbi.nlm.ni...
Null ppi.NAA38 View Gene Set 0.001618 21 0.02838 131 Protein-protein-interaction for NAA38 www.ncbi.nlm.ni...
Null ppi.RPAP1 View Gene Set 0.001649 24 0.02842 132 Protein-protein-interaction for RPAP1 www.ncbi.nlm.ni...
Null ppi.STAT1 View Gene Set 0.001643 31 0.02842 132 Protein-protein-interaction for STAT1 www.ncbi.nlm.ni...
Null ppi.NUDT18 View Gene Set 0.00167 26 0.02842 132 Protein-protein-interaction for NUDT18 www.ncbi.nlm.ni...
Null ppi.CDC7 View Gene Set 0.001658 7 0.02842 132 Protein-protein-interaction for CDC7 www.ncbi.nlm.ni...
Null ppi.SEH1L View Gene Set 0.001686 6 0.02848 136 Protein-protein-interaction for SEH1L www.ncbi.nlm.ni...
Null ppi.USP43 View Gene Set 0.001745 9 0.02885 137 Protein-protein-interaction for USP43 www.ncbi.nlm.ni...
Null ppi.NEDD4 View Gene Set 0.001758 18 0.02885 137 Protein-protein-interaction for NEDD4 www.ncbi.nlm.ni...
Null ppi.RNMTL1 View Gene Set 0.001758 8 0.02885 137 Protein-protein-interaction for RNMTL1 www.ncbi.nlm.ni...
Null ppi.ZRANB2 View Gene Set 0.001724 6 0.02885 137 Protein-protein-interaction for ZRANB2 www.ncbi.nlm.ni...
Null ppi.PRMT1 View Gene Set 0.001771 15 0.02885 141 Protein-protein-interaction for PRMT1 www.ncbi.nlm.ni...
Null ppi.WDR8 View Gene Set 0.001809 23 0.02926 142 Protein-protein-interaction for WDR8 www.ncbi.nlm.ni...
Null ppi.NCOR1 View Gene Set 0.001858 84 0.02985 143 Protein-protein-interaction for NCOR1 www.ncbi.nlm.ni...
Null ppi.TADA3 View Gene Set 0.00198 21 0.03014 144 Protein-protein-interaction for TADA3 www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 0.00194 9 0.03014 144 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.ORC5L View Gene Set 0.001938 8 0.03014 144 Protein-protein-interaction for ORC5L www.ncbi.nlm.ni...
Null ppi.SRRT View Gene Set 0.001948 7 0.03014 144 Protein-protein-interaction for SRRT www.ncbi.nlm.ni...
Null ppi.XRN1 View Gene Set 0.001982 12 0.03014 144 Protein-protein-interaction for XRN1 www.ncbi.nlm.ni...
Null ppi.POLR3E View Gene Set 0.001946 6 0.03014 144 Protein-protein-interaction for POLR3E www.ncbi.nlm.ni...
Null ppi.TRAF6 View Gene Set 0.00197 47 0.03014 144 Protein-protein-interaction for TRAF6 www.ncbi.nlm.ni...
Null ppi.CHD1L View Gene Set 0.001955 15 0.03014 144 Protein-protein-interaction for CHD1L www.ncbi.nlm.ni...
Null ppi.HCFC2 View Gene Set 0.002005 7 0.03025 152 Protein-protein-interaction for HCFC2 www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 0.002015 11 0.03025 152 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 0.002047 10 0.03053 154 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.MYSM1 View Gene Set 0.002138 13 0.03168 155 Protein-protein-interaction for MYSM1 www.ncbi.nlm.ni...
Null ppi.STAP1 View Gene Set 0.002191 7 0.03227 156 Protein-protein-interaction for STAP1 www.ncbi.nlm.ni...
Null ppi.UBA1 View Gene Set 0.002237 7 0.03273 157 Protein-protein-interaction for UBA1 www.ncbi.nlm.ni...
Null ppi.CD2BP2 View Gene Set 0.002257 13 0.03281 158 Protein-protein-interaction for CD2BP2 www.ncbi.nlm.ni...
Null ppi.KAT5 View Gene Set 0.002333 51 0.03295 159 Protein-protein-interaction for KAT5 www.ncbi.nlm.ni...
Null ppi.EEF1G View Gene Set 0.002293 9 0.03295 159 Protein-protein-interaction for EEF1G www.ncbi.nlm.ni...
Null ppi.SIN3A View Gene Set 0.002303 104 0.03295 159 Protein-protein-interaction for SIN3A www.ncbi.nlm.ni...
Null ppi.KPNA3 View Gene Set 0.002312 6 0.03295 159 Protein-protein-interaction for KPNA3 www.ncbi.nlm.ni...
Null ppi.ORC1L View Gene Set 0.002338 9 0.03295 159 Protein-protein-interaction for ORC1L www.ncbi.nlm.ni...
Null ppi.TERF1 View Gene Set 0.002377 15 0.03329 164 Protein-protein-interaction for TERF1 www.ncbi.nlm.ni...
Null ppi.HIST4H4 View Gene Set 0.002407 21 0.0333 165 Protein-protein-interaction for HIST4H4 www.ncbi.nlm.ni...
Null ppi.MIS12 View Gene Set 0.0024 9 0.0333 165 Protein-protein-interaction for MIS12 www.ncbi.nlm.ni...
Null ppi.MED13 View Gene Set 0.002436 10 0.0335 167 Protein-protein-interaction for MED13 www.ncbi.nlm.ni...
Null ppi.CPSF6 View Gene Set 0.002478 12 0.03359 168 Protein-protein-interaction for CPSF6 www.ncbi.nlm.ni...
Null ppi.SF3B3 View Gene Set 0.002466 16 0.03359 168 Protein-protein-interaction for SF3B3 www.ncbi.nlm.ni...
Null ppi.ZNF496 View Gene Set 0.002486 13 0.03359 168 Protein-protein-interaction for ZNF496 www.ncbi.nlm.ni...
Null ppi.FAN1 View Gene Set 0.002539 13 0.0341 171 Protein-protein-interaction for FAN1 www.ncbi.nlm.ni...
Null ppi.GEMIN5 View Gene Set 0.002707 11 0.03615 172 Protein-protein-interaction for GEMIN5 www.ncbi.nlm.ni...
Null ppi.SETD1A View Gene Set 0.002728 7 0.03622 173 Protein-protein-interaction for SETD1A www.ncbi.nlm.ni...
Null ppi.ITCH View Gene Set 0.002761 57 0.03645 174 Protein-protein-interaction for ITCH www.ncbi.nlm.ni...
Null ppi.ANAPC2 View Gene Set 0.002821 6 0.03693 175 Protein-protein-interaction for ANAPC2 www.ncbi.nlm.ni...
Null ppi.LSM7 View Gene Set 0.002843 13 0.03693 175 Protein-protein-interaction for LSM7 www.ncbi.nlm.ni...
Null ppi.HIST2H2BE View Gene Set 0.002846 17 0.03693 175 Protein-protein-interaction for HIST2H2BE www.ncbi.nlm.ni...
Null ppi.MYST1 View Gene Set 0.002887 14 0.03726 178 Protein-protein-interaction for MYST1 www.ncbi.nlm.ni...
Null ppi.NLK View Gene Set 0.003084 15 0.03958 179 Protein-protein-interaction for NLK www.ncbi.nlm.ni...
Null ppi.HUWE1 View Gene Set 0.003125 8 0.03971 180 Protein-protein-interaction for HUWE1 www.ncbi.nlm.ni...
Null ppi.PCNA View Gene Set 0.003131 40 0.03971 180 Protein-protein-interaction for PCNA www.ncbi.nlm.ni...
Null ppi.ZBTB8A View Gene Set 0.003151 18 0.03971 180 Protein-protein-interaction for ZBTB8A www.ncbi.nlm.ni...
Null ppi.TAF1A View Gene Set 0.003164 14 0.03971 180 Protein-protein-interaction for TAF1A www.ncbi.nlm.ni...
Null ppi.TAF1D View Gene Set 0.003189 21 0.03981 184 Protein-protein-interaction for TAF1D www.ncbi.nlm.ni...
Null ppi.SNUPN View Gene Set 0.003334 10 0.04071 185 Protein-protein-interaction for SNUPN www.ncbi.nlm.ni...
Null ppi.PTGES3 View Gene Set 0.00334 10 0.04071 185 Protein-protein-interaction for PTGES3 www.ncbi.nlm.ni...
Null ppi.SAFB View Gene Set 0.00335 7 0.04071 185 Protein-protein-interaction for SAFB www.ncbi.nlm.ni...
Null ppi.XPO1 View Gene Set 0.003309 24 0.04071 185 Protein-protein-interaction for XPO1 www.ncbi.nlm.ni...
Null ppi.PTTG1 View Gene Set 0.003325 11 0.04071 185 Protein-protein-interaction for PTTG1 www.ncbi.nlm.ni...
Null ppi.POLR2A View Gene Set 0.003401 25 0.0411 190 Protein-protein-interaction for POLR2A www.ncbi.nlm.ni...
Null ppi.TAF12 View Gene Set 0.003418 10 0.0411 190 Protein-protein-interaction for TAF12 www.ncbi.nlm.ni...
Null ppi.USP3 View Gene Set 0.003493 15 0.04179 192 Protein-protein-interaction for USP3 www.ncbi.nlm.ni...
Null ppi.WBP11 View Gene Set 0.003568 10 0.04233 193 Protein-protein-interaction for WBP11 www.ncbi.nlm.ni...
Null ppi.ING3 View Gene Set 0.003612 10 0.04233 193 Protein-protein-interaction for ING3 www.ncbi.nlm.ni...
Null ppi.WDR33 View Gene Set 0.003595 13 0.04233 193 Protein-protein-interaction for WDR33 www.ncbi.nlm.ni...
Null ppi.RAD17 View Gene Set 0.003611 13 0.04233 193 Protein-protein-interaction for RAD17 www.ncbi.nlm.ni...
Null ppi.MED15 View Gene Set 0.003634 15 0.04237 197 Protein-protein-interaction for MED15 www.ncbi.nlm.ni...
Null ppi.SMNDC1 View Gene Set 0.003716 8 0.04289 198 Protein-protein-interaction for SMNDC1 www.ncbi.nlm.ni...
Null ppi.MSH2 View Gene Set 0.003703 16 0.04289 198 Protein-protein-interaction for MSH2 www.ncbi.nlm.ni...
Null ppi.IMMT View Gene Set 0.003895 15 0.04451 200 Protein-protein-interaction for IMMT www.ncbi.nlm.ni...

Gene Set Collection: ppi.HPRD

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.SFRS12 View Gene Set 3.436e-14 49 8.157e-11 1 Protein-protein-interaction for SFRS12 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 8.431e-07 166 0.001001 2 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 2.431e-06 13 0.001924 3 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.SUMO4 View Gene Set 5.245e-06 76 0.002491 4 Protein-protein-interaction for SUMO4 www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 4.624e-06 55 0.002491 4 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 1.337e-05 14 0.005292 6 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.TCERG1 View Gene Set 2.351e-05 20 0.007972 7 Protein-protein-interaction for TCERG1 www.ncbi.nlm.ni...
Null ppi.NDRG1 View Gene Set 0.0002346 58 0.03419 8 Protein-protein-interaction for NDRG1 www.ncbi.nlm.ni...
Null ppi.IVNS1ABP View Gene Set 0.0001308 6 0.03419 8 Protein-protein-interaction for IVNS1ABP www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 0.0002381 22 0.03419 8 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.NUP62 View Gene Set 0.0003577 19 0.03419 8 Protein-protein-interaction for NUP62 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 0.000363 11 0.03419 8 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.ORC5L View Gene Set 0.000247 10 0.03419 8 Protein-protein-interaction for ORC5L www.ncbi.nlm.ni...
Null ppi.MPP6 View Gene Set 0.0003232 18 0.03419 8 Protein-protein-interaction for MPP6 www.ncbi.nlm.ni...
Null ppi.NAA38 View Gene Set 0.0003764 20 0.03419 8 Protein-protein-interaction for NAA38 www.ncbi.nlm.ni...
Null ppi.WBP11 View Gene Set 0.0002501 15 0.03419 8 Protein-protein-interaction for WBP11 www.ncbi.nlm.ni...
Null ppi.PLK1 View Gene Set 0.0003117 14 0.03419 8 Protein-protein-interaction for PLK1 www.ncbi.nlm.ni...
Null ppi.XRN1 View Gene Set 0.0003694 24 0.03419 8 Protein-protein-interaction for XRN1 www.ncbi.nlm.ni...
Null ppi.THAP1 View Gene Set 0.0003406 10 0.03419 8 Protein-protein-interaction for THAP1 www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 0.0002553 18 0.03419 8 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 0.0002771 13 0.03419 8 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 0.0001674 10 0.03419 8 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.DNAJC7 View Gene Set 0.0001641 8 0.03419 8 Protein-protein-interaction for DNAJC7 www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 0.0001596 17 0.03419 8 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.YWHAG View Gene Set 0.0003888 106 0.03419 8 Protein-protein-interaction for YWHAG www.ncbi.nlm.ni...
Null ppi.SNIP1 View Gene Set 0.0002331 27 0.03419 8 Protein-protein-interaction for SNIP1 www.ncbi.nlm.ni...
Null ppi.PTTG1 View Gene Set 0.0002682 8 0.03419 8 Protein-protein-interaction for PTTG1 www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 0.000404 8 0.03426 28 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.BRAP View Gene Set 0.0004574 5 0.0362 29 Protein-protein-interaction for BRAP www.ncbi.nlm.ni...
Null ppi.MDC1 View Gene Set 0.0004522 11 0.0362 29 Protein-protein-interaction for MDC1 www.ncbi.nlm.ni...
Null ppi.EIF5 View Gene Set 0.0005174 6 0.03722 31 Protein-protein-interaction for EIF5 www.ncbi.nlm.ni...
Null ppi.UPF2 View Gene Set 0.0004994 16 0.03722 31 Protein-protein-interaction for UPF2 www.ncbi.nlm.ni...
Null ppi.COIL View Gene Set 0.0005073 19 0.03722 31 Protein-protein-interaction for COIL www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 0.000565 27 0.03801 34 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.SGOL1 View Gene Set 0.0005563 20 0.03801 34 Protein-protein-interaction for SGOL1 www.ncbi.nlm.ni...
Null ppi.XRN2 View Gene Set 0.0007686 9 0.03801 34 Protein-protein-interaction for XRN2 www.ncbi.nlm.ni...
Null ppi.PUF60 View Gene Set 0.0007376 9 0.03801 34 Protein-protein-interaction for PUF60 www.ncbi.nlm.ni...
Null ppi.NCBP2 View Gene Set 0.000742 6 0.03801 34 Protein-protein-interaction for NCBP2 www.ncbi.nlm.ni...
Null ppi.SF3B1 View Gene Set 0.0007233 9 0.03801 34 Protein-protein-interaction for SF3B1 www.ncbi.nlm.ni...
Null ppi.PABPC1 View Gene Set 0.0006371 21 0.03801 34 Protein-protein-interaction for PABPC1 www.ncbi.nlm.ni...
Null ppi.PRMT1 View Gene Set 0.000626 13 0.03801 34 Protein-protein-interaction for PRMT1 www.ncbi.nlm.ni...
Null ppi.RAN View Gene Set 0.0007403 14 0.03801 34 Protein-protein-interaction for RAN www.ncbi.nlm.ni...
Null ppi.SMN2 View Gene Set 0.0006303 9 0.03801 34 Protein-protein-interaction for SMN2 www.ncbi.nlm.ni...
Null ppi.ZNF655 View Gene Set 0.0005926 8 0.03801 34 Protein-protein-interaction for ZNF655 www.ncbi.nlm.ni...
Null ppi.NUDT18 View Gene Set 0.0007029 27 0.03801 34 Protein-protein-interaction for NUDT18 www.ncbi.nlm.ni...
Null ppi.EIF3G View Gene Set 0.0006689 7 0.03801 34 Protein-protein-interaction for EIF3G www.ncbi.nlm.ni...
Null ppi.EIF2S2 View Gene Set 0.0007666 17 0.03801 34 Protein-protein-interaction for EIF2S2 www.ncbi.nlm.ni...
Null ppi.TAF1A View Gene Set 0.0006557 7 0.03801 34 Protein-protein-interaction for TAF1A www.ncbi.nlm.ni...
Null ppi.SAFB View Gene Set 0.000847 8 0.04104 49 Protein-protein-interaction for SAFB www.ncbi.nlm.ni...
Null ppi.POLR2G View Gene Set 0.0009007 7 0.04277 50 Protein-protein-interaction for POLR2G www.ncbi.nlm.ni...
Null ppi.LSM1 View Gene Set 0.0009244 16 0.04303 51 Protein-protein-interaction for LSM1 www.ncbi.nlm.ni...
Null ppi.SRPK1 View Gene Set 0.0009796 12 0.04322 52 Protein-protein-interaction for SRPK1 www.ncbi.nlm.ni...
Null ppi.NOL12 View Gene Set 0.0009831 7 0.04322 52 Protein-protein-interaction for NOL12 www.ncbi.nlm.ni...
Null ppi.CDC16 View Gene Set 0.0009654 10 0.04322 52 Protein-protein-interaction for CDC16 www.ncbi.nlm.ni...
Null ppi.PSMB7 View Gene Set 0.001004 6 0.04333 55 Protein-protein-interaction for PSMB7 www.ncbi.nlm.ni...
Null ppi.HDAC1 View Gene Set 0.001097 28 0.04649 56 Protein-protein-interaction for HDAC1 www.ncbi.nlm.ni...
Null ppi.ANAPC2 View Gene Set 0.001159 6 0.04828 57 Protein-protein-interaction for ANAPC2 www.ncbi.nlm.ni...
Null ppi.NUP98 View Gene Set 0.00121 8 0.04954 58 Protein-protein-interaction for NUP98 www.ncbi.nlm.ni...

Gene Set Collection: ppi.anyDB

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.155871 View Gene Set 2.162e-38 251 7.771e-35 1 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 7.954e-24 147 1.429e-20 2 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.SRRM2 View Gene Set 8.563e-19 101 1.026e-15 3 Protein-protein-interaction for SRRM2 www.ncbi.nlm.ni...
Null ppi.SRRM1 View Gene Set 1.181e-14 66 9.423e-12 4 Protein-protein-interaction for SRRM1 www.ncbi.nlm.ni...
Null ppi.SFRS12 View Gene Set 1.311e-14 50 9.423e-12 4 Protein-protein-interaction for SFRS12 www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 7.843e-12 96 4.698e-09 6 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.WBP4 View Gene Set 4.025e-11 35 2.067e-08 7 Protein-protein-interaction for WBP4 www.ncbi.nlm.ni...
Null ppi.CDT1 View Gene Set 4.396e-09 42 1.975e-06 8 Protein-protein-interaction for CDT1 www.ncbi.nlm.ni...
Null ppi.KHDRBS2 View Gene Set 6.785e-09 48 2.71e-06 9 Protein-protein-interaction for KHDRBS2 www.ncbi.nlm.ni...
Null ppi.GPN1 View Gene Set 3.79e-08 27 1.304e-05 10 Protein-protein-interaction for GPN1 www.ncbi.nlm.ni...
Null ppi.72462 View Gene Set 3.99e-08 42 1.304e-05 10 Protein-protein-interaction for 72462 www.ncbi.nlm.ni...
Null ppi.UCHL5 View Gene Set 5.223e-08 34 1.564e-05 12 Protein-protein-interaction for UCHL5 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 1.308e-07 220 3.616e-05 13 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.HIST1H4A View Gene Set 3.336e-07 31 8.563e-05 14 Protein-protein-interaction for HIST1H4A www.ncbi.nlm.ni...
Null ppi.PSMD13 View Gene Set 4.748e-07 20 0.0001138 15 Protein-protein-interaction for PSMD13 www.ncbi.nlm.ni...
Null ppi.EIF3F View Gene Set 8.558e-07 25 0.0001922 16 Protein-protein-interaction for EIF3F www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 1.052e-06 21 0.0002225 17 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 1.31e-06 16 0.0002616 18 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 1.401e-06 17 0.000265 19 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 1.971e-06 43 0.0003542 20 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.SF3B1 View Gene Set 3.317e-06 31 0.0004844 21 Protein-protein-interaction for SF3B1 www.ncbi.nlm.ni...
Null ppi.RNU12-2P View Gene Set 3.37e-06 18 0.0004844 21 Protein-protein-interaction for RNU12-2P www.ncbi.nlm.ni...
Null ppi.RNU11 View Gene Set 3.37e-06 18 0.0004844 21 Protein-protein-interaction for RNU11 www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 3.056e-06 25 0.0004844 21 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.PSMD6 View Gene Set 3.19e-06 23 0.0004844 21 Protein-protein-interaction for PSMD6 www.ncbi.nlm.ni...
Null ppi.USP39 View Gene Set 4.668e-06 16 0.0005992 26 Protein-protein-interaction for USP39 www.ncbi.nlm.ni...
Null ppi.NUP62 View Gene Set 4.42e-06 25 0.0005992 26 Protein-protein-interaction for NUP62 www.ncbi.nlm.ni...
Null ppi.EIF3H View Gene Set 4.639e-06 16 0.0005992 26 Protein-protein-interaction for EIF3H www.ncbi.nlm.ni...
Null ppi.SUMO4 View Gene Set 5.245e-06 76 0.0006501 29 Protein-protein-interaction for SUMO4 www.ncbi.nlm.ni...
Null ppi.RRP1B View Gene Set 5.722e-06 21 0.0006855 30 Protein-protein-interaction for RRP1B www.ncbi.nlm.ni...
Null ppi.SGOL1 View Gene Set 9.942e-06 24 0.001117 31 Protein-protein-interaction for SGOL1 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 9.734e-06 15 0.001117 31 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.PRKDC View Gene Set 1.152e-05 49 0.001255 33 Protein-protein-interaction for PRKDC www.ncbi.nlm.ni...
Null ppi.GTF3C3 View Gene Set 1.407e-05 12 0.001488 34 Protein-protein-interaction for GTF3C3 www.ncbi.nlm.ni...
Null ppi.CHTF18 View Gene Set 1.559e-05 13 0.001601 35 Protein-protein-interaction for CHTF18 www.ncbi.nlm.ni...
Null ppi.PSMD14 View Gene Set 2.295e-05 16 0.002291 36 Protein-protein-interaction for PSMD14 www.ncbi.nlm.ni...
Null ppi.RNPS1 View Gene Set 2.842e-05 44 0.002699 37 Protein-protein-interaction for RNPS1 www.ncbi.nlm.ni...
Null ppi.NAA38 View Gene Set 2.854e-05 28 0.002699 37 Protein-protein-interaction for NAA38 www.ncbi.nlm.ni...
Null ppi.PRPF8 View Gene Set 3.184e-05 14 0.002725 39 Protein-protein-interaction for PRPF8 www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 3.163e-05 46 0.002725 39 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.UPF2 View Gene Set 3.092e-05 19 0.002725 39 Protein-protein-interaction for UPF2 www.ncbi.nlm.ni...
Null ppi.USP14 View Gene Set 3.038e-05 22 0.002725 39 Protein-protein-interaction for USP14 www.ncbi.nlm.ni...
Null ppi.RUVBL2 View Gene Set 3.506e-05 72 0.002788 43 Protein-protein-interaction for RUVBL2 www.ncbi.nlm.ni...
Null ppi.PSMD7 View Gene Set 3.643e-05 13 0.002788 43 Protein-protein-interaction for PSMD7 www.ncbi.nlm.ni...
Null ppi.RPA1 View Gene Set 3.49e-05 24 0.002788 43 Protein-protein-interaction for RPA1 www.ncbi.nlm.ni...
Null ppi.SUMO2 View Gene Set 3.646e-05 55 0.002788 43 Protein-protein-interaction for SUMO2 www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 3.469e-05 52 0.002788 43 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.USP36 View Gene Set 4.611e-05 17 0.003452 48 Protein-protein-interaction for USP36 www.ncbi.nlm.ni...
Null ppi.THAP1 View Gene Set 5.211e-05 12 0.003675 49 Protein-protein-interaction for THAP1 www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 5.126e-05 21 0.003675 49 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.RUVBL1 View Gene Set 5.215e-05 41 0.003675 49 Protein-protein-interaction for RUVBL1 www.ncbi.nlm.ni...
Null ppi.RPAP3 View Gene Set 6.101e-05 30 0.004217 52 Protein-protein-interaction for RPAP3 www.ncbi.nlm.ni...
Null ppi.PUF60 View Gene Set 6.402e-05 35 0.004261 53 Protein-protein-interaction for PUF60 www.ncbi.nlm.ni...
Null ppi.MLH1 View Gene Set 6.368e-05 12 0.004261 53 Protein-protein-interaction for MLH1 www.ncbi.nlm.ni...
Null ppi.KAT2A View Gene Set 6.97e-05 14 0.004374 55 Protein-protein-interaction for KAT2A www.ncbi.nlm.ni...
Null ppi.PRPF19 View Gene Set 6.883e-05 9 0.004374 55 Protein-protein-interaction for PRPF19 www.ncbi.nlm.ni...
Null ppi.ORC5L View Gene Set 6.789e-05 11 0.004374 55 Protein-protein-interaction for ORC5L www.ncbi.nlm.ni...
Null ppi.MDC1 View Gene Set 7.059e-05 24 0.004374 55 Protein-protein-interaction for MDC1 www.ncbi.nlm.ni...
Null ppi.WWOX View Gene Set 7.203e-05 26 0.004388 59 Protein-protein-interaction for WWOX www.ncbi.nlm.ni...
Null ppi.CDC20 View Gene Set 7.407e-05 5 0.004437 60 Protein-protein-interaction for CDC20 www.ncbi.nlm.ni...
Null ppi.TERF2 View Gene Set 8.408e-05 10 0.004954 61 Protein-protein-interaction for TERF2 www.ncbi.nlm.ni...
Null ppi.EIF3B View Gene Set 8.568e-05 11 0.004967 62 Protein-protein-interaction for EIF3B www.ncbi.nlm.ni...
Null ppi.LYAR View Gene Set 8.936e-05 26 0.005098 63 Protein-protein-interaction for LYAR www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 9.934e-05 20 0.005466 64 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.TAF10 View Gene Set 0.0001003 29 0.005466 64 Protein-protein-interaction for TAF10 www.ncbi.nlm.ni...
Null ppi.SUPT3H View Gene Set 0.0001004 14 0.005466 64 Protein-protein-interaction for SUPT3H www.ncbi.nlm.ni...
Null ppi.MGMT View Gene Set 0.0001099 28 0.005896 67 Protein-protein-interaction for MGMT www.ncbi.nlm.ni...
Null ppi.RAD51 View Gene Set 0.0001116 20 0.005897 68 Protein-protein-interaction for RAD51 www.ncbi.nlm.ni...
Null ppi.UBA1 View Gene Set 0.0001168 11 0.006085 69 Protein-protein-interaction for UBA1 www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 0.0001284 33 0.006591 70 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.C20orf20 View Gene Set 0.0001302 16 0.006592 71 Protein-protein-interaction for C20orf20 www.ncbi.nlm.ni...
Null ppi.BRF2 View Gene Set 0.0001484 25 0.007409 72 Protein-protein-interaction for BRF2 www.ncbi.nlm.ni...
Null ppi.IVNS1ABP View Gene Set 0.0001575 7 0.007465 73 Protein-protein-interaction for IVNS1ABP www.ncbi.nlm.ni...
Null ppi.TCERG1 View Gene Set 0.0001628 39 0.007465 73 Protein-protein-interaction for TCERG1 www.ncbi.nlm.ni...
Null ppi.COPS8 View Gene Set 0.0001636 13 0.007465 73 Protein-protein-interaction for COPS8 www.ncbi.nlm.ni...
Null ppi.SRPK2 View Gene Set 0.0001593 7 0.007465 73 Protein-protein-interaction for SRPK2 www.ncbi.nlm.ni...
Null ppi.TP53BP2 View Gene Set 0.0001595 17 0.007465 73 Protein-protein-interaction for TP53BP2 www.ncbi.nlm.ni...
Null ppi.DNAJC7 View Gene Set 0.0001641 8 0.007465 73 Protein-protein-interaction for DNAJC7 www.ncbi.nlm.ni...
Null ppi.UBE3A View Gene Set 0.0001605 22 0.007465 73 Protein-protein-interaction for UBE3A www.ncbi.nlm.ni...
Null ppi.XRN1 View Gene Set 0.0001741 25 0.007723 80 Protein-protein-interaction for XRN1 www.ncbi.nlm.ni...
Null ppi.AURKA View Gene Set 0.0001733 16 0.007723 80 Protein-protein-interaction for AURKA www.ncbi.nlm.ni...
Null ppi.PSMD10 View Gene Set 0.0001762 16 0.007724 82 Protein-protein-interaction for PSMD10 www.ncbi.nlm.ni...
Null ppi.E2F4 View Gene Set 0.0002007 16 0.008692 83 Protein-protein-interaction for E2F4 www.ncbi.nlm.ni...
Null ppi.BRAP View Gene Set 0.0002059 6 0.008811 84 Protein-protein-interaction for BRAP www.ncbi.nlm.ni...
Null ppi.GIYD2 View Gene Set 0.0002177 32 0.009203 85 Protein-protein-interaction for GIYD2 www.ncbi.nlm.ni...
Null ppi.NDRG1 View Gene Set 0.0002346 58 0.009802 86 Protein-protein-interaction for NDRG1 www.ncbi.nlm.ni...
Null ppi.TPX2 View Gene Set 0.0002397 5 0.009841 87 Protein-protein-interaction for TPX2 www.ncbi.nlm.ni...
Null ppi.HIST2H2AC View Gene Set 0.0002412 14 0.009841 87 Protein-protein-interaction for HIST2H2AC www.ncbi.nlm.ni...
Null ppi.MED30 View Gene Set 0.0002437 26 0.009841 87 Protein-protein-interaction for MED30 www.ncbi.nlm.ni...
Null ppi.C16orf53 View Gene Set 0.0002684 9 0.01072 90 Protein-protein-interaction for C16orf53 www.ncbi.nlm.ni...
Null ppi.POLR3C View Gene Set 0.0002765 10 0.01083 91 Protein-protein-interaction for POLR3C www.ncbi.nlm.ni...
Null ppi.KPNA6 View Gene Set 0.0002772 12 0.01083 91 Protein-protein-interaction for KPNA6 www.ncbi.nlm.ni...
Null ppi.MSH2 View Gene Set 0.000285 20 0.01101 93 Protein-protein-interaction for MSH2 www.ncbi.nlm.ni...
Null ppi.MCRS1 View Gene Set 0.0002906 17 0.01111 94 Protein-protein-interaction for MCRS1 www.ncbi.nlm.ni...
Null ppi.TERF1 View Gene Set 0.0003003 18 0.01136 95 Protein-protein-interaction for TERF1 www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 0.0003042 12 0.01139 96 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.ORC1L View Gene Set 0.0003207 11 0.01188 97 Protein-protein-interaction for ORC1L www.ncbi.nlm.ni...
Null ppi.PPARGC1A View Gene Set 0.000331 39 0.01202 98 Protein-protein-interaction for PPARGC1A www.ncbi.nlm.ni...
Null ppi.PDS5A View Gene Set 0.0003293 6 0.01202 98 Protein-protein-interaction for PDS5A www.ncbi.nlm.ni...
Null ppi.CD3EAP View Gene Set 0.0003432 8 0.01203 100 Protein-protein-interaction for CD3EAP www.ncbi.nlm.ni...
Null ppi.FANCA View Gene Set 0.0003474 14 0.01203 100 Protein-protein-interaction for FANCA www.ncbi.nlm.ni...
Null ppi.CXXC1 View Gene Set 0.0003394 14 0.01203 100 Protein-protein-interaction for CXXC1 www.ncbi.nlm.ni...
Null ppi.PCNA View Gene Set 0.0003481 47 0.01203 100 Protein-protein-interaction for PCNA www.ncbi.nlm.ni...
Null ppi.WDR77 View Gene Set 0.0003514 18 0.01203 100 Protein-protein-interaction for WDR77 www.ncbi.nlm.ni...
Null ppi.PAAF1 View Gene Set 0.0003491 20 0.01203 100 Protein-protein-interaction for PAAF1 www.ncbi.nlm.ni...
Null ppi.MCPH1 View Gene Set 0.0003687 17 0.0125 106 Protein-protein-interaction for MCPH1 www.ncbi.nlm.ni...
Null ppi.EIF3C View Gene Set 0.0003779 9 0.01269 107 Protein-protein-interaction for EIF3C www.ncbi.nlm.ni...
Null ppi.HIST2H3C View Gene Set 0.0003844 31 0.01279 108 Protein-protein-interaction for HIST2H3C www.ncbi.nlm.ni...
Null ppi.COPS7A View Gene Set 0.000402 19 0.0129 109 Protein-protein-interaction for COPS7A www.ncbi.nlm.ni...
Null ppi.WDR48 View Gene Set 0.0003974 52 0.0129 109 Protein-protein-interaction for WDR48 www.ncbi.nlm.ni...
Null ppi.SNIP1 View Gene Set 0.0004039 28 0.0129 109 Protein-protein-interaction for SNIP1 www.ncbi.nlm.ni...
Null ppi.KAT2B View Gene Set 0.0003968 88 0.0129 109 Protein-protein-interaction for KAT2B www.ncbi.nlm.ni...
Null ppi.MED17 View Gene Set 0.0004056 16 0.0129 109 Protein-protein-interaction for MED17 www.ncbi.nlm.ni...
Null ppi.POLR1E View Gene Set 0.0004207 13 0.01324 114 Protein-protein-interaction for POLR1E www.ncbi.nlm.ni...
Null ppi.SNORD3A View Gene Set 0.0004236 9 0.01324 114 Protein-protein-interaction for SNORD3A www.ncbi.nlm.ni...
Null ppi.TP53BP1 View Gene Set 0.0004321 17 0.01339 116 Protein-protein-interaction for TP53BP1 www.ncbi.nlm.ni...
Null ppi.USP11 View Gene Set 0.0004392 17 0.01349 117 Protein-protein-interaction for USP11 www.ncbi.nlm.ni...
Null ppi.NUTF2 View Gene Set 0.0004561 5 0.01375 118 Protein-protein-interaction for NUTF2 www.ncbi.nlm.ni...
Null ppi.FEN1 View Gene Set 0.0004699 11 0.01375 118 Protein-protein-interaction for FEN1 www.ncbi.nlm.ni...
Null ppi.ORC6L View Gene Set 0.0004707 15 0.01375 118 Protein-protein-interaction for ORC6L www.ncbi.nlm.ni...
Null ppi.SRRT View Gene Set 0.0004668 8 0.01375 118 Protein-protein-interaction for SRRT www.ncbi.nlm.ni...
Null ppi.PLK1 View Gene Set 0.0004639 22 0.01375 118 Protein-protein-interaction for PLK1 www.ncbi.nlm.ni...
Null ppi.HIST1H3A View Gene Set 0.0004662 31 0.01375 118 Protein-protein-interaction for HIST1H3A www.ncbi.nlm.ni...
Null ppi.SMNDC1 View Gene Set 0.0004857 10 0.01408 124 Protein-protein-interaction for SMNDC1 www.ncbi.nlm.ni...
Null ppi.LSM1 View Gene Set 0.0005097 18 0.01447 125 Protein-protein-interaction for LSM1 www.ncbi.nlm.ni...
Null ppi.MPP6 View Gene Set 0.0005115 19 0.01447 125 Protein-protein-interaction for MPP6 www.ncbi.nlm.ni...
Null ppi.COIL View Gene Set 0.0005073 20 0.01447 125 Protein-protein-interaction for COIL www.ncbi.nlm.ni...
Null ppi.EIF5 View Gene Set 0.0005174 6 0.01453 128 Protein-protein-interaction for EIF5 www.ncbi.nlm.ni...
Null ppi.SUPT16H View Gene Set 0.0005356 15 0.01481 129 Protein-protein-interaction for SUPT16H www.ncbi.nlm.ni...
Null ppi.PABPC1 View Gene Set 0.0005352 37 0.01481 129 Protein-protein-interaction for PABPC1 www.ncbi.nlm.ni...
Null ppi.ANAPC2 View Gene Set 0.0005535 8 0.01519 131 Protein-protein-interaction for ANAPC2 www.ncbi.nlm.ni...
Null ppi.TAF1A View Gene Set 0.0005769 16 0.01571 132 Protein-protein-interaction for TAF1A www.ncbi.nlm.ni...
Null ppi.MCM5 View Gene Set 0.0005822 7 0.01573 133 Protein-protein-interaction for MCM5 www.ncbi.nlm.ni...
Null ppi.ZNF655 View Gene Set 0.0005926 8 0.01589 134 Protein-protein-interaction for ZNF655 www.ncbi.nlm.ni...
Null ppi.PTTG1 View Gene Set 0.0006175 13 0.01644 135 Protein-protein-interaction for PTTG1 www.ncbi.nlm.ni...
Null ppi.GIGYF2 View Gene Set 0.0006497 19 0.01717 136 Protein-protein-interaction for GIGYF2 www.ncbi.nlm.ni...
Null ppi.BCL7C View Gene Set 0.0006631 11 0.0174 137 Protein-protein-interaction for BCL7C www.ncbi.nlm.ni...
Null ppi.PPP4R2 View Gene Set 0.0006764 7 0.01741 138 Protein-protein-interaction for PPP4R2 www.ncbi.nlm.ni...
Null ppi.FAF2 View Gene Set 0.0006916 8 0.01741 138 Protein-protein-interaction for FAF2 www.ncbi.nlm.ni...
Null ppi.PRMT1 View Gene Set 0.0006904 17 0.01741 138 Protein-protein-interaction for PRMT1 www.ncbi.nlm.ni...
Null ppi.WBP11 View Gene Set 0.0006929 17 0.01741 138 Protein-protein-interaction for WBP11 www.ncbi.nlm.ni...
Null ppi.ATXN7 View Gene Set 0.0006803 11 0.01741 138 Protein-protein-interaction for ATXN7 www.ncbi.nlm.ni...
Null ppi.EIF3G View Gene Set 0.0006843 8 0.01741 138 Protein-protein-interaction for EIF3G www.ncbi.nlm.ni...
Null ppi.NUDT18 View Gene Set 0.0007029 27 0.01754 144 Protein-protein-interaction for NUDT18 www.ncbi.nlm.ni...
Null ppi.DSCC1 View Gene Set 0.0007113 6 0.01763 145 Protein-protein-interaction for DSCC1 www.ncbi.nlm.ni...
Null ppi.E2F1 View Gene Set 0.0007428 24 0.01792 146 Protein-protein-interaction for E2F1 www.ncbi.nlm.ni...
Null ppi.NCBP2 View Gene Set 0.000742 6 0.01792 146 Protein-protein-interaction for NCBP2 www.ncbi.nlm.ni...
Null ppi.USP7 View Gene Set 0.0007431 32 0.01792 146 Protein-protein-interaction for USP7 www.ncbi.nlm.ni...
Null ppi.HIST2H2BE View Gene Set 0.0007354 27 0.01792 146 Protein-protein-interaction for HIST2H2BE www.ncbi.nlm.ni...
Null ppi.XRN2 View Gene Set 0.0007686 9 0.01829 150 Protein-protein-interaction for XRN2 www.ncbi.nlm.ni...
Null ppi.EIF2S2 View Gene Set 0.0007666 17 0.01829 150 Protein-protein-interaction for EIF2S2 www.ncbi.nlm.ni...
Null ppi.THOC4 View Gene Set 0.0007998 5 0.01867 152 Protein-protein-interaction for THOC4 www.ncbi.nlm.ni...
Null ppi.YWHAQ View Gene Set 0.000801 104 0.01867 152 Protein-protein-interaction for YWHAQ www.ncbi.nlm.ni...
Null ppi.GAR1 View Gene Set 0.0008038 10 0.01867 152 Protein-protein-interaction for GAR1 www.ncbi.nlm.ni...
Null ppi.ZRANB2 View Gene Set 0.0008052 11 0.01867 152 Protein-protein-interaction for ZRANB2 www.ncbi.nlm.ni...
Null ppi.PAXIP1 View Gene Set 0.000851 19 0.01961 156 Protein-protein-interaction for PAXIP1 www.ncbi.nlm.ni...
Null ppi.CPSF6 View Gene Set 0.0008786 13 0.01991 157 Protein-protein-interaction for CPSF6 www.ncbi.nlm.ni...
Null ppi.MRE11A View Gene Set 0.0008796 16 0.01991 157 Protein-protein-interaction for MRE11A www.ncbi.nlm.ni...
Null ppi.SMN2 View Gene Set 0.0008808 11 0.01991 157 Protein-protein-interaction for SMN2 www.ncbi.nlm.ni...
Null ppi.TXNL4A View Gene Set 0.0009854 6 0.02186 160 Protein-protein-interaction for TXNL4A www.ncbi.nlm.ni...
Null ppi.SRPK1 View Gene Set 0.0009796 12 0.02186 160 Protein-protein-interaction for SRPK1 www.ncbi.nlm.ni...
Null ppi.NOL12 View Gene Set 0.0009831 7 0.02186 160 Protein-protein-interaction for NOL12 www.ncbi.nlm.ni...
Null ppi.MCM8 View Gene Set 0.000996 6 0.02196 163 Protein-protein-interaction for MCM8 www.ncbi.nlm.ni...
Null ppi.PSMB7 View Gene Set 0.001004 6 0.022 164 Protein-protein-interaction for PSMB7 www.ncbi.nlm.ni...
Null ppi.KLF13 View Gene Set 0.001033 10 0.02249 165 Protein-protein-interaction for KLF13 www.ncbi.nlm.ni...
Null ppi.ZNF335 View Gene Set 0.001039 8 0.02249 165 Protein-protein-interaction for ZNF335 www.ncbi.nlm.ni...
Null ppi.RIBIN View Gene Set 0.001048 8 0.02252 167 Protein-protein-interaction for RIBIN www.ncbi.nlm.ni...
Null ppi.ZNF384 View Gene Set 0.001053 7 0.02252 167 Protein-protein-interaction for ZNF384 www.ncbi.nlm.ni...
Null ppi.CDC16 View Gene Set 0.001071 14 0.02278 169 Protein-protein-interaction for CDC16 www.ncbi.nlm.ni...
Null ppi.HUWE1 View Gene Set 0.0011 14 0.02303 170 Protein-protein-interaction for HUWE1 www.ncbi.nlm.ni...
Null ppi.CDCA5 View Gene Set 0.001095 6 0.02303 170 Protein-protein-interaction for CDCA5 www.ncbi.nlm.ni...
Null ppi.RFWD2 View Gene Set 0.001102 26 0.02303 170 Protein-protein-interaction for RFWD2 www.ncbi.nlm.ni...
Null ppi.CTCF View Gene Set 0.00114 11 0.02341 173 Protein-protein-interaction for CTCF www.ncbi.nlm.ni...
Null ppi.E2F3 View Gene Set 0.001159 8 0.02341 173 Protein-protein-interaction for E2F3 www.ncbi.nlm.ni...
Null ppi.NUP43 View Gene Set 0.001149 6 0.02341 173 Protein-protein-interaction for NUP43 www.ncbi.nlm.ni...
Null ppi.DMAP1 View Gene Set 0.001159 16 0.02341 173 Protein-protein-interaction for DMAP1 www.ncbi.nlm.ni...
Null ppi.RAD17 View Gene Set 0.001153 14 0.02341 173 Protein-protein-interaction for RAD17 www.ncbi.nlm.ni...
Null ppi.USP42 View Gene Set 0.001131 24 0.02341 173 Protein-protein-interaction for USP42 www.ncbi.nlm.ni...
Null ppi.EIF3A View Gene Set 0.001207 13 0.02424 179 Protein-protein-interaction for EIF3A www.ncbi.nlm.ni...
Null ppi.BRIP1 View Gene Set 0.001274 8 0.02543 180 Protein-protein-interaction for BRIP1 www.ncbi.nlm.ni...
Null ppi.ZCCHC10 View Gene Set 0.001303 6 0.02587 181 Protein-protein-interaction for ZCCHC10 www.ncbi.nlm.ni...
Null ppi.UXT View Gene Set 0.001342 11 0.0265 182 Protein-protein-interaction for UXT www.ncbi.nlm.ni...
Null ppi.SET View Gene Set 0.001377 24 0.02704 183 Protein-protein-interaction for SET www.ncbi.nlm.ni...
Null ppi.RAD54B View Gene Set 0.001394 9 0.02723 184 Protein-protein-interaction for RAD54B www.ncbi.nlm.ni...
Null ppi.CCT3 View Gene Set 0.001424 15 0.02767 185 Protein-protein-interaction for CCT3 www.ncbi.nlm.ni...
Null ppi.DDX39 View Gene Set 0.001434 7 0.02771 186 Protein-protein-interaction for DDX39 www.ncbi.nlm.ni...
Null ppi.CBX3 View Gene Set 0.001444 26 0.02775 187 Protein-protein-interaction for CBX3 www.ncbi.nlm.ni...
Null ppi.RBMX View Gene Set 0.001455 15 0.0278 188 Protein-protein-interaction for RBMX www.ncbi.nlm.ni...
Null ppi.SIP1 View Gene Set 0.001462 17 0.0278 188 Protein-protein-interaction for SIP1 www.ncbi.nlm.ni...
Null ppi.TOR1AIP2 View Gene Set 0.001521 7 0.02877 190 Protein-protein-interaction for TOR1AIP2 www.ncbi.nlm.ni...
Null ppi.SNRPA View Gene Set 0.001557 6 0.02929 191 Protein-protein-interaction for SNRPA www.ncbi.nlm.ni...
Null ppi.SERTAD2 View Gene Set 0.001578 6 0.02953 192 Protein-protein-interaction for SERTAD2 www.ncbi.nlm.ni...
Null ppi.G3BP1 View Gene Set 0.001638 19 0.0305 193 Protein-protein-interaction for G3BP1 www.ncbi.nlm.ni...
Null ppi.RPAP1 View Gene Set 0.001649 24 0.03055 194 Protein-protein-interaction for RPAP1 www.ncbi.nlm.ni...
Null ppi.POLD3 View Gene Set 0.001685 6 0.03077 195 Protein-protein-interaction for POLD3 www.ncbi.nlm.ni...
Null ppi.LSM5 View Gene Set 0.00167 6 0.03077 195 Protein-protein-interaction for LSM5 www.ncbi.nlm.ni...
Null ppi.SEH1L View Gene Set 0.001686 6 0.03077 195 Protein-protein-interaction for SEH1L www.ncbi.nlm.ni...
Null ppi.GEMIN5 View Gene Set 0.001733 14 0.03145 198 Protein-protein-interaction for GEMIN5 www.ncbi.nlm.ni...
Null ppi.USP43 View Gene Set 0.001745 9 0.03152 199 Protein-protein-interaction for USP43 www.ncbi.nlm.ni...
Null ppi.RNMTL1 View Gene Set 0.001758 8 0.03159 200 Protein-protein-interaction for RNMTL1 www.ncbi.nlm.ni...

Gene Set Collection: pathwayCommons.cell-map

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null TNF alpha/NF-kB View Gene Set 3.685e-06 170 3.685e-05 1 CELL_MAP - TNF alpha/NF-kB gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.nci-nature

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Validated targets of C-MYC transcriptional activation View Gene Set 3.015e-11 80 5.608e-09 1 NCI_NATURE - Validated targets of C-MYC transcriptional activation gene set www.pathwaycomm...
Null Signaling by Aurora kinases View Gene Set 9.269e-09 98 8.62e-07 2 NCI_NATURE - Signaling by Aurora kinases gene set www.pathwaycomm...
Null Aurora B signaling View Gene Set 3.559e-08 41 2.207e-06 3 NCI_NATURE - Aurora B signaling gene set www.pathwaycomm...
Null Polo-like kinase signaling events in the cell cycle View Gene Set 7.896e-08 109 3.672e-06 4 NCI_NATURE - Polo-like kinase signaling events in the cell cycle gene set www.pathwaycomm...
Null PLK1 signaling events View Gene Set 1.338e-07 104 4.978e-06 5 NCI_NATURE - PLK1 signaling events gene set www.pathwaycomm...
Null C-MYC pathway View Gene Set 1.779e-06 149 5.516e-05 6 NCI_NATURE - C-MYC pathway gene set www.pathwaycomm...
Null E2F transcription factor network View Gene Set 0.0002054 73 0.005458 7 NCI_NATURE - E2F transcription factor network gene set www.pathwaycomm...
Null Aurora A signaling View Gene Set 0.0003788 64 0.008807 8 NCI_NATURE - Aurora A signaling gene set www.pathwaycomm...
Null BARD1 signaling events View Gene Set 0.0007629 29 0.01419 9 NCI_NATURE - BARD1 signaling events gene set www.pathwaycomm...
Null Regulation of Telomerase View Gene Set 0.0007354 68 0.01419 9 NCI_NATURE - Regulation of Telomerase gene set www.pathwaycomm...
Null FOXM1 transcription factor network View Gene Set 0.001414 42 0.02391 11 NCI_NATURE - FOXM1 transcription factor network gene set www.pathwaycomm...
Null Signaling events mediated by HDAC Class I View Gene Set 0.002792 114 0.04327 12 NCI_NATURE - Signaling events mediated by HDAC Class I gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.reactome

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Gene Expression View Gene Set 9.558e-40 381 1.068e-36 1 REACTOME - Gene Expression gene set www.pathwaycomm...
Null Cell Cycle Mitotic View Gene Set 2.874e-34 312 1.605e-31 2 REACTOME - Cell Cycle Mitotic gene set www.pathwaycomm... Mitotic&format=...
Null DNA Replication View Gene Set 1.747e-31 200 6.506e-29 3 REACTOME - DNA Replication gene set www.pathwaycomm...
Null Mitotic M-M/G1 phases View Gene Set 7.172e-30 180 2.003e-27 4 REACTOME - Mitotic M-M/G1 phases gene set www.pathwaycomm...
Null Processing of Capped Intron-Containing Pre-mRNA View Gene Set 9.769e-28 138 2.182e-25 5 REACTOME - Processing of Capped Intron-Containing Pre-mRNA gene set www.pathwaycomm...
Null mRNA Processing View Gene Set 1.315e-24 158 2.449e-22 6 REACTOME - mRNA Processing gene set www.pathwaycomm...
Null Formation and Maturation of mRNA Transcript View Gene Set 4.208e-24 185 6.714e-22 7 REACTOME - Formation and Maturation of mRNA Transcript gene set www.pathwaycomm...
Null mRNA Splicing - Major Pathway View Gene Set 2.203e-22 107 2.734e-20 8 REACTOME - mRNA Splicing - Major Pathway gene set www.pathwaycomm...
Null mRNA Splicing View Gene Set 2.203e-22 107 2.734e-20 8 REACTOME - mRNA Splicing gene set www.pathwaycomm...
Null M Phase View Gene Set 3.658e-21 90 4.086e-19 10 REACTOME - M Phase gene set www.pathwaycomm...
Null Mitotic Prometaphase View Gene Set 1.133e-19 86 1.151e-17 11 REACTOME - Mitotic Prometaphase gene set www.pathwaycomm...
Null Metabolism of RNA View Gene Set 1.443e-19 174 1.343e-17 12 REACTOME - Metabolism of RNA gene set www.pathwaycomm...
Null Cell Cycle Checkpoints View Gene Set 8.777e-15 124 7.542e-13 13 REACTOME - Cell Cycle Checkpoints gene set www.pathwaycomm...
Null Transport of Mature Transcript to Cytoplasm View Gene Set 6.455e-13 55 5.15e-11 14 REACTOME - Transport of Mature Transcript to Cytoplasm gene set www.pathwaycomm...
Null Transport of Mature mRNA derived from an Intron-Containing Transcript View Gene Set 2.527e-12 51 1.882e-10 15 REACTOME - Transport of Mature mRNA derived from an Intron-Containing Transcript gene set www.pathwaycomm...
Null Metabolism of mRNA View Gene Set 4.578e-12 125 3.196e-10 16 REACTOME - Metabolism of mRNA gene set www.pathwaycomm...
Null Regulation of mitotic cell cycle View Gene Set 5.409e-12 95 3.356e-10 17 REACTOME - Regulation of mitotic cell cycle gene set www.pathwaycomm...
Null APC/C-mediated degradation of cell cycle proteins View Gene Set 5.409e-12 95 3.356e-10 17 REACTOME - APC/C-mediated degradation of cell cycle proteins gene set www.pathwaycomm...
Null Translation View Gene Set 8.477e-12 120 4.622e-10 19 REACTOME - Translation gene set www.pathwaycomm...
Null Assembly of the pre-replicative complex View Gene Set 9.104e-12 75 4.622e-10 19 REACTOME - Assembly of the pre-replicative complex gene set www.pathwaycomm...
Null S Phase View Gene Set 8.764e-12 113 4.622e-10 19 REACTOME - S Phase gene set www.pathwaycomm...
Null Mitotic G1-G1/S phases View Gene Set 8.274e-12 113 4.622e-10 19 REACTOME - Mitotic G1-G1/S phases gene set www.pathwaycomm...
Null G1/S Transition View Gene Set 9.581e-12 104 4.653e-10 23 REACTOME - G1/S Transition gene set www.pathwaycomm...
Null Synthesis of DNA View Gene Set 1.207e-11 102 5.62e-10 24 REACTOME - Synthesis of DNA gene set www.pathwaycomm...
Null Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 1.539e-11 86 6.875e-10 25 REACTOME - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null DNA Replication Pre-Initiation View Gene Set 1.937e-11 90 8.015e-10 26 REACTOME - DNA Replication Pre-Initiation gene set www.pathwaycomm...
Null M/G1 Transition View Gene Set 1.937e-11 90 8.015e-10 26 REACTOME - M/G1 Transition gene set www.pathwaycomm...
Null Regulation of APC/C activators between G1/S and early anaphase View Gene Set 8.21e-11 88 3.275e-09 28 REACTOME - Regulation of APC/C activators between G1/S and early anaphase gene set www.pathwaycomm...
Null Regulation of DNA replication View Gene Set 1.415e-10 81 5.449e-09 29 REACTOME - Regulation of DNA replication gene set www.pathwaycomm...
Null Post-Elongation Processing of the Transcript View Gene Set 1.841e-10 43 6.425e-09 30 REACTOME - Post-Elongation Processing of the Transcript gene set www.pathwaycomm...
Null Cleavage of Growing Transcript in the Termination Region View Gene Set 1.841e-10 43 6.425e-09 30 REACTOME - Cleavage of Growing Transcript in the Termination Region gene set www.pathwaycomm...
Null RNA Polymerase II Transcription Termination View Gene Set 1.841e-10 43 6.425e-09 30 REACTOME - RNA Polymerase II Transcription Termination gene set www.pathwaycomm...
Null snRNP Assembly View Gene Set 5.765e-10 50 1.894e-08 33 REACTOME - snRNP Assembly gene set www.pathwaycomm...
Null Metabolism of non-coding RNA View Gene Set 5.765e-10 50 1.894e-08 33 REACTOME - Metabolism of non-coding RNA gene set www.pathwaycomm...
Null Cap-dependent Translation Initiation View Gene Set 6.169e-10 113 1.914e-08 35 REACTOME - Cap-dependent Translation Initiation gene set www.pathwaycomm...
Null Eukaryotic Translation Initiation View Gene Set 6.169e-10 113 1.914e-08 35 REACTOME - Eukaryotic Translation Initiation gene set www.pathwaycomm...
Null HIV Infection View Gene Set 9.621e-10 194 2.905e-08 37 REACTOME - HIV Infection gene set www.pathwaycomm...
Null Host Interactions of HIV factors View Gene Set 1.258e-09 132 3.698e-08 38 REACTOME - Host Interactions of HIV factors gene set www.pathwaycomm...
Null Removal of licensing factors from origins View Gene Set 1.3e-09 78 3.722e-08 39 REACTOME - Removal of licensing factors from origins gene set www.pathwaycomm...
Null Post-Elongation Processing of Intron-Containing pre-mRNA View Gene Set 1.616e-09 34 4.402e-08 40 REACTOME - Post-Elongation Processing of Intron-Containing pre-mRNA gene set www.pathwaycomm...
Null mRNA 3'-end processing View Gene Set 1.616e-09 34 4.402e-08 40 REACTOME - mRNA 3'-end processing gene set www.pathwaycomm...
Null APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 View Gene Set 1.696e-09 77 4.509e-08 42 REACTOME - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 gene set www.pathwaycomm...
Null G2/M Checkpoints View Gene Set 2.43e-09 43 6.312e-08 43 REACTOME - G2/M Checkpoints gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 2.506e-09 77 6.361e-08 44 REACTOME - APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null CDT1 association with the CDC6:ORC:origin complex View Gene Set 4.055e-09 66 1.006e-07 45 REACTOME - CDT1 association with the CDC6:ORC:origin complex gene set www.pathwaycomm...
Null Switching of origins to a post-replicative state View Gene Set 5.066e-09 76 1.204e-07 46 REACTOME - Switching of origins to a post-replicative state gene set www.pathwaycomm...
Null Orc1 removal from chromatin View Gene Set 5.066e-09 76 1.204e-07 46 REACTOME - Orc1 removal from chromatin gene set www.pathwaycomm...
Null GTP hydrolysis and joining of the 60S ribosomal subunit View Gene Set 5.457e-09 106 1.27e-07 48 REACTOME - GTP hydrolysis and joining of the 60S ribosomal subunit gene set www.pathwaycomm...
Null Transcription View Gene Set 6.405e-09 178 1.46e-07 49 REACTOME - Transcription gene set www.pathwaycomm...
Null 3' -UTR-mediated translational regulation View Gene Set 8.983e-09 105 1.967e-07 50 REACTOME - 3' -UTR-mediated translational regulation gene set www.pathwaycomm...
Null L13a-mediated translational silencing of Ceruloplasmin expression View Gene Set 8.983e-09 105 1.967e-07 50 REACTOME - L13a-mediated translational silencing of Ceruloplasmin expression gene set www.pathwaycomm...
Null Regulation of mRNA Stability by Proteins that Bind AU-rich Elements View Gene Set 1.043e-08 95 2.24e-07 52 REACTOME - Regulation of mRNA Stability by Proteins that Bind AU-rich Elements gene set www.pathwaycomm...
Null Cdc20:Phospho-APC/C mediated degradation of Cyclin A View Gene Set 1.261e-08 75 2.658e-07 53 REACTOME - Cdc20:Phospho-APC/C mediated degradation of Cyclin A gene set www.pathwaycomm...
Null Influenza Infection View Gene Set 2.052e-08 143 4.245e-07 54 REACTOME - Influenza Infection gene set www.pathwaycomm...
Null Interactions of Rev with host cellular proteins View Gene Set 2.9e-08 33 5.891e-07 55 REACTOME - Interactions of Rev with host cellular proteins gene set www.pathwaycomm...
Null Activation of ATR in response to replication stress View Gene Set 3.925e-08 37 7.829e-07 56 REACTOME - Activation of ATR in response to replication stress gene set www.pathwaycomm...
Null p53-Independent G1/S DNA damage checkpoint View Gene Set 5.096e-08 62 9.813e-07 57 REACTOME - p53-Independent G1/S DNA damage checkpoint gene set www.pathwaycomm...
Null p53-Independent DNA Damage Response View Gene Set 5.096e-08 62 9.813e-07 57 REACTOME - p53-Independent DNA Damage Response gene set www.pathwaycomm...
Null Deadenylation-dependent mRNA decay View Gene Set 7.625e-08 46 1.444e-06 59 REACTOME - Deadenylation-dependent mRNA decay gene set www.pathwaycomm...
Null Transport of Mature mRNAs Derived from Intronless Transcripts View Gene Set 8.125e-08 36 1.513e-06 60 REACTOME - Transport of Mature mRNAs Derived from Intronless Transcripts gene set www.pathwaycomm...
Null Rev-mediated nuclear export of HIV-1 RNA View Gene Set 9.238e-08 32 1.692e-06 61 REACTOME - Rev-mediated nuclear export of HIV-1 RNA gene set www.pathwaycomm...
Null Ubiquitin Mediated Degradation of Phosphorylated Cdc25A View Gene Set 1.181e-07 61 2.086e-06 62 REACTOME - Ubiquitin Mediated Degradation of Phosphorylated Cdc25A gene set www.pathwaycomm...
Null Ribosomal scanning and start codon recognition View Gene Set 1.195e-07 56 2.086e-06 62 REACTOME - Ribosomal scanning and start codon recognition gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of Securin View Gene Set 1.183e-07 72 2.086e-06 62 REACTOME - APC/C:Cdc20 mediated degradation of Securin gene set www.pathwaycomm...
Null SCF-beta-TrCP mediated degradation of Emi1 View Gene Set 1.267e-07 60 2.178e-06 65 REACTOME - SCF-beta-TrCP mediated degradation of Emi1 gene set www.pathwaycomm...
Null Transport of Mature mRNA Derived from an Intronless Transcript View Gene Set 1.381e-07 35 2.337e-06 66 REACTOME - Transport of Mature mRNA Derived from an Intronless Transcript gene set www.pathwaycomm...
Null Translation initiation complex formation View Gene Set 1.434e-07 56 2.39e-06 67 REACTOME - Translation initiation complex formation gene set www.pathwaycomm...
Null RNA Polymerase II Transcription View Gene Set 1.501e-07 101 2.466e-06 68 REACTOME - RNA Polymerase II Transcription gene set www.pathwaycomm...
Null Activation of the mRNA upon binding of the cap-binding complex and eIFs and subsequent binding to 43S View Gene Set 1.722e-07 57 2.788e-06 69 REACTOME - Activation of the mRNA upon binding of the cap-binding complex and eIFs and subsequent binding to 43S gene set www.pathwaycomm... and subsequent ...
Null Influenza Life Cycle View Gene Set 1.855e-07 138 2.959e-06 70 REACTOME - Influenza Life Cycle gene set www.pathwaycomm...
Null G2/M DNA damage checkpoint View Gene Set 1.939e-07 29 3.05e-06 71 REACTOME - G2/M DNA damage checkpoint gene set www.pathwaycomm...
Null Transport of the SLBP Dependant Mature mRNA View Gene Set 1.968e-07 33 3.054e-06 72 REACTOME - Transport of the SLBP Dependant Mature mRNA gene set www.pathwaycomm...
Null tRNA Aminoacylation View Gene Set 2.639e-07 42 4.037e-06 73 REACTOME - tRNA Aminoacylation gene set www.pathwaycomm...
Null Autodegradation of Cdh1 by Cdh1:APC/C View Gene Set 2.732e-07 67 4.124e-06 74 REACTOME - Autodegradation of Cdh1 by Cdh1:APC/C gene set www.pathwaycomm...
Null Destabilization of mRNA by AUF1 (hnRNP D0) View Gene Set 3.056e-07 63 4.551e-06 75 REACTOME - Destabilization of mRNA by AUF1 (hnRNP D0) gene set www.pathwaycomm...
Null Transport of the SLBP independent Mature mRNA View Gene Set 3.354e-07 32 4.929e-06 76 REACTOME - Transport of the SLBP independent Mature mRNA gene set www.pathwaycomm...
Null Nuclear import of Rev protein View Gene Set 4.422e-07 30 6.414e-06 77 REACTOME - Nuclear import of Rev protein gene set www.pathwaycomm...
Null Regulation of activated PAK-2p34 by proteasome mediated degradation View Gene Set 4.542e-07 57 6.505e-06 78 REACTOME - Regulation of activated PAK-2p34 by proteasome mediated degradation gene set www.pathwaycomm...
Null Autodegradation of the E3 ubiquitin ligase COP1 View Gene Set 5.218e-07 60 7.378e-06 79 REACTOME - Autodegradation of the E3 ubiquitin ligase COP1 gene set www.pathwaycomm...
Null Ubiquitin-dependent degradation of Cyclin D1 View Gene Set 6.158e-07 59 8.492e-06 80 REACTOME - Ubiquitin-dependent degradation of Cyclin D1 gene set www.pathwaycomm...
Null Ubiquitin-dependent degradation of Cyclin D View Gene Set 6.158e-07 59 8.492e-06 80 REACTOME - Ubiquitin-dependent degradation of Cyclin D gene set www.pathwaycomm...
Null Olfactory Signaling Pathway View Gene Set 7.477e-07 370 1.019e-05 82 REACTOME - Olfactory Signaling Pathway gene set www.pathwaycomm...
Null Vpu mediated degradation of CD4 View Gene Set 8.379e-07 57 1.128e-05 83 REACTOME - Vpu mediated degradation of CD4 gene set www.pathwaycomm...
Null Stabilization of p53 View Gene Set 9.749e-07 61 1.296e-05 84 REACTOME - Stabilization of p53 gene set www.pathwaycomm...
Null Cytosolic tRNA aminoacylation View Gene Set 9.864e-07 24 1.296e-05 84 REACTOME - Cytosolic tRNA aminoacylation gene set www.pathwaycomm...
Null Degradation of beta-catenin by the destruction complex View Gene Set 1.037e-06 56 1.332e-05 86 REACTOME - Degradation of beta-catenin by the destruction complex gene set www.pathwaycomm...
Null Signaling by Wnt View Gene Set 1.037e-06 56 1.332e-05 86 REACTOME - Signaling by Wnt gene set www.pathwaycomm...
Null SCF(Skp2)-mediated degradation of p27/p21 View Gene Set 1.05e-06 52 1.332e-05 88 REACTOME - SCF(Skp2)-mediated degradation of p27/p21 gene set www.pathwaycomm...
Null CDK-mediated phosphorylation and removal of Cdc6 View Gene Set 1.259e-06 58 1.58e-05 89 REACTOME - CDK-mediated phosphorylation and removal of Cdc6 gene set www.pathwaycomm...
Null Transport of Ribonucleoproteins into the Host Nucleus View Gene Set 1.279e-06 29 1.587e-05 90 REACTOME - Transport of Ribonucleoproteins into the Host Nucleus gene set www.pathwaycomm...
Null Mitotic G2-G2/M phases View Gene Set 1.294e-06 98 1.588e-05 91 REACTOME - Mitotic G2-G2/M phases gene set www.pathwaycomm...
Null G1/S DNA Damage Checkpoints View Gene Set 1.442e-06 68 1.751e-05 92 REACTOME - G1/S DNA Damage Checkpoints gene set www.pathwaycomm...
Null mRNA Splicing - Minor Pathway View Gene Set 1.475e-06 42 1.771e-05 93 REACTOME - mRNA Splicing - Minor Pathway gene set www.pathwaycomm...
Null NEP/NS2 Interacts with the Cellular Export Machinery View Gene Set 1.637e-06 29 1.945e-05 94 REACTOME - NEP/NS2 Interacts with the Cellular Export Machinery gene set www.pathwaycomm...
Null Formation of a pool of free 40S subunits View Gene Set 2.36e-06 95 2.774e-05 95 REACTOME - Formation of a pool of free 40S subunits gene set www.pathwaycomm...
Null Regulation of ornithine decarboxylase (ODC) View Gene Set 2.711e-06 62 3.154e-05 96 REACTOME - Regulation of ornithine decarboxylase (ODC) gene set www.pathwaycomm...
Null G2/M Transition View Gene Set 4.177e-06 96 4.81e-05 97 REACTOME - G2/M Transition gene set www.pathwaycomm...
Null Export of Viral Ribonucleoproteins from Nucleus View Gene Set 5.476e-06 31 6.242e-05 98 REACTOME - Export of Viral Ribonucleoproteins from Nucleus gene set www.pathwaycomm...
Null Vif-mediated degradation of APOBEC3G View Gene Set 5.677e-06 61 6.405e-05 99 REACTOME - Vif-mediated degradation of APOBEC3G gene set www.pathwaycomm...
Null Metabolism of nucleotides View Gene Set 5.806e-06 66 6.485e-05 100 REACTOME - Metabolism of nucleotides gene set www.pathwaycomm...
Null Folding of actin by CCT/TriC View Gene Set 6.705e-06 9 7.415e-05 101 REACTOME - Folding of actin by CCT/TriC gene set www.pathwaycomm...
Null Late Phase of HIV Life Cycle View Gene Set 1.003e-05 92 0.0001088 102 REACTOME - Late Phase of HIV Life Cycle gene set www.pathwaycomm...
Null Cyclin A:Cdk2-associated events at S phase entry View Gene Set 9.943e-06 62 0.0001088 102 REACTOME - Cyclin A:Cdk2-associated events at S phase entry gene set www.pathwaycomm...
Null Association of TriC/CCT with target proteins during biosynthesis View Gene Set 1.021e-05 9 0.0001097 104 REACTOME - Association of TriC/CCT with target proteins during biosynthesis gene set www.pathwaycomm...
Null Recruitment of NuMA to mitotic centrosomes View Gene Set 1.038e-05 14 0.0001104 105 REACTOME - Recruitment of NuMA to mitotic centrosomes gene set www.pathwaycomm...
Null HIV Life Cycle View Gene Set 1.057e-05 103 0.0001114 106 REACTOME - HIV Life Cycle gene set www.pathwaycomm...
Null p53-Dependent G1/S DNA damage checkpoint View Gene Set 1.126e-05 64 0.0001164 107 REACTOME - p53-Dependent G1/S DNA damage checkpoint gene set www.pathwaycomm...
Null p53-Dependent G1 DNA Damage Response View Gene Set 1.126e-05 64 0.0001164 107 REACTOME - p53-Dependent G1 DNA Damage Response gene set www.pathwaycomm...
Null Formation of tubulin folding intermediates by CCT/TriC View Gene Set 1.312e-05 8 0.0001344 109 REACTOME - Formation of tubulin folding intermediates by CCT/TriC gene set www.pathwaycomm...
Null Phosphorylation of Emi1 View Gene Set 1.391e-05 12 0.00014 110 REACTOME - Phosphorylation of Emi1 gene set www.pathwaycomm...
Null DNA strand elongation View Gene Set 1.39e-05 31 0.00014 110 REACTOME - DNA strand elongation gene set www.pathwaycomm...
Null Eukaryotic Translation Elongation View Gene Set 1.459e-05 88 0.0001455 112 REACTOME - Eukaryotic Translation Elongation gene set www.pathwaycomm...
Null Regulation of Apoptosis View Gene Set 1.512e-05 66 0.0001494 113 REACTOME - Regulation of Apoptosis gene set www.pathwaycomm...
Null Cyclin E associated events during G1/S transition View Gene Set 1.634e-05 64 0.0001601 114 REACTOME - Cyclin E associated events during G1/S transition gene set www.pathwaycomm...
Null Centrosome maturation View Gene Set 1.815e-05 73 0.0001748 115 REACTOME - Centrosome maturation gene set www.pathwaycomm...
Null Recruitment of mitotic centrosome proteins and complexes View Gene Set 1.815e-05 72 0.0001748 115 REACTOME - Recruitment of mitotic centrosome proteins and complexes gene set www.pathwaycomm...
Null Vpr-mediated nuclear import of PICs View Gene Set 2.402e-05 31 0.0002293 117 REACTOME - Vpr-mediated nuclear import of PICs gene set www.pathwaycomm...
Null Chaperonin-mediated protein folding View Gene Set 2.694e-05 16 0.000255 118 REACTOME - Chaperonin-mediated protein folding gene set www.pathwaycomm...
Null Formation of the ternary complex and subsequently the 43S complex View Gene Set 2.849e-05 49 0.0002674 119 REACTOME - Formation of the ternary complex and subsequently the 43S complex gene set www.pathwaycomm... and subsequentl... the 43S complex...
Null Interactions of Vpr with host cellular proteins View Gene Set 3.12e-05 34 0.0002905 120 REACTOME - Interactions of Vpr with host cellular proteins gene set www.pathwaycomm...
Null Pyrimidine biosynthesis View Gene Set 3.197e-05 6 0.0002927 121 REACTOME - Pyrimidine biosynthesis gene set www.pathwaycomm...
Null Activation of the pre-replicative complex View Gene Set 3.174e-05 30 0.0002927 121 REACTOME - Activation of the pre-replicative complex gene set www.pathwaycomm...
Null Unwinding of DNA View Gene Set 3.273e-05 11 0.0002973 123 REACTOME - Unwinding of DNA gene set www.pathwaycomm...
Null Regulation of Glucokinase by Glucokinase Regulatory Protein View Gene Set 3.718e-05 29 0.0003349 124 REACTOME - Regulation of Glucokinase by Glucokinase Regulatory Protein gene set www.pathwaycomm...
Null Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding View Gene Set 4.063e-05 15 0.0003631 125 REACTOME - Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding gene set www.pathwaycomm...
Null Glucose transport View Gene Set 4.283e-05 38 0.0003797 126 REACTOME - Glucose transport gene set www.pathwaycomm...
Null Extension of Telomeres View Gene Set 5.178e-05 28 0.0004488 127 REACTOME - Extension of Telomeres gene set www.pathwaycomm...
Null Homologous Recombination Repair View Gene Set 5.183e-05 22 0.0004488 127 REACTOME - Homologous Recombination Repair gene set www.pathwaycomm...
Null Homologous recombination repair of replication-independent double-strand breaks View Gene Set 5.183e-05 22 0.0004488 127 REACTOME - Homologous recombination repair of replication-independent double-strand breaks gene set www.pathwaycomm...
Null Phosphorylation of the APC/C View Gene Set 5.511e-05 26 0.0004735 130 REACTOME - Phosphorylation of the APC/C gene set www.pathwaycomm...
Null CDC6 association with the ORC:origin complex View Gene Set 5.566e-05 11 0.0004746 131 REACTOME - CDC6 association with the ORC:origin complex gene set www.pathwaycomm...
Null Peptide chain elongation View Gene Set 6.426e-05 85 0.0005438 132 REACTOME - Peptide chain elongation gene set www.pathwaycomm...
Null Post-Elongation Processing of Intronless pre-mRNA View Gene Set 6.96e-05 23 0.0005802 133 REACTOME - Post-Elongation Processing of Intronless pre-mRNA gene set www.pathwaycomm...
Null Processing of Capped Intronless Pre-mRNA View Gene Set 6.96e-05 23 0.0005802 133 REACTOME - Processing of Capped Intronless Pre-mRNA gene set www.pathwaycomm...
Null Hexose transport View Gene Set 7.532e-05 40 0.0006232 135 REACTOME - Hexose transport gene set www.pathwaycomm...
Null DNA Repair View Gene Set 7.643e-05 108 0.0006277 136 REACTOME - DNA Repair gene set www.pathwaycomm...
Null Prefoldin mediated transfer of substrate to CCT/TriC View Gene Set 8.283e-05 14 0.0006719 137 REACTOME - Prefoldin mediated transfer of substrate to CCT/TriC gene set www.pathwaycomm...
Null Mitotic Telophase /Cytokinesis View Gene Set 8.301e-05 10 0.0006719 137 REACTOME - Mitotic Telophase /Cytokinesis gene set www.pathwaycomm...
Null Eukaryotic Translation Termination View Gene Set 8.516e-05 85 0.0006843 139 REACTOME - Eukaryotic Translation Termination gene set www.pathwaycomm...
Null Chromosome Maintenance View Gene Set 9.178e-05 69 0.0007323 140 REACTOME - Chromosome Maintenance gene set www.pathwaycomm...
Null Metabolism of proteins View Gene Set 0.0001285 263 0.001018 141 REACTOME - Metabolism of proteins gene set www.pathwaycomm...
Null Purine ribonucleoside monophosphate biosynthesis View Gene Set 0.0001385 7 0.00109 142 REACTOME - Purine ribonucleoside monophosphate biosynthesis gene set www.pathwaycomm...
Null Double-Strand Break Repair View Gene Set 0.0001459 27 0.001132 143 REACTOME - Double-Strand Break Repair gene set www.pathwaycomm...
Null G1/S-Specific Transcription View Gene Set 0.0001455 16 0.001132 143 REACTOME - G1/S-Specific Transcription gene set www.pathwaycomm...
Null Apoptosis View Gene Set 0.0001595 148 0.001229 145 REACTOME - Apoptosis gene set www.pathwaycomm...
Null E2F mediated regulation of DNA replication View Gene Set 0.0001759 28 0.001346 146 REACTOME - E2F mediated regulation of DNA replication gene set www.pathwaycomm...
Null Gap-filling DNA repair synthesis and ligation in TC-NER View Gene Set 0.0003954 16 0.002984 147 REACTOME - Gap-filling DNA repair synthesis and ligation in TC-NER gene set www.pathwaycomm...
Null Gap-filling DNA repair synthesis and ligation in GG-NER View Gene Set 0.0003954 16 0.002984 147 REACTOME - Gap-filling DNA repair synthesis and ligation in GG-NER gene set www.pathwaycomm...
Null Deadenylation of mRNA View Gene Set 0.0004563 22 0.003421 149 REACTOME - Deadenylation of mRNA gene set www.pathwaycomm...
Null Viral mRNA Translation View Gene Set 0.0004762 85 0.003546 150 REACTOME - Viral mRNA Translation gene set www.pathwaycomm...
Null Influenza Viral RNA Transcription and Replication View Gene Set 0.0006359 101 0.004704 151 REACTOME - Influenza Viral RNA Transcription and Replication gene set www.pathwaycomm...
Null Polo-like kinase mediated events View Gene Set 0.0006917 10 0.005083 152 REACTOME - Polo-like kinase mediated events gene set www.pathwaycomm...
Null Telomere Extension By Telomerase View Gene Set 0.0007681 6 0.005608 153 REACTOME - Telomere Extension By Telomerase gene set www.pathwaycomm...
Null Processing of Intronless Pre-mRNAs View Gene Set 0.0008827 14 0.006402 154 REACTOME - Processing of Intronless Pre-mRNAs gene set www.pathwaycomm...
Null Association of licensing factors with the pre-replicative complex View Gene Set 0.001054 15 0.007595 155 REACTOME - Association of licensing factors with the pre-replicative complex gene set www.pathwaycomm...
Null Mitotic Metaphase/Anaphase Transition View Gene Set 0.001102 8 0.007891 156 REACTOME - Mitotic Metaphase/Anaphase Transition gene set www.pathwaycomm...
Null E2F-enabled inhibition of pre-replication complex formation View Gene Set 0.001133 10 0.008058 157 REACTOME - E2F-enabled inhibition of pre-replication complex formation gene set www.pathwaycomm...
Null Metabolism of folate and pterines View Gene Set 0.001148 8 0.008115 158 REACTOME - Metabolism of folate and pterines gene set www.pathwaycomm...
Null Repair synthesis for gap-filling by DNA polymerase in TC-NER View Gene Set 0.001277 15 0.008916 159 REACTOME - Repair synthesis for gap-filling by DNA polymerase in TC-NER gene set www.pathwaycomm...
Null Repair synthesis of patch ~27-30 bases long by DNA polymerase View Gene Set 0.001277 15 0.008916 159 REACTOME - Repair synthesis of patch ~27-30 bases long by DNA polymerase gene set www.pathwaycomm...
Null Activation of PUMA and translocation to mitochondria View Gene Set 0.001523 4 0.01057 161 REACTOME - Activation of PUMA and translocation to mitochondria gene set www.pathwaycomm...
Null Protein folding View Gene Set 0.001568 29 0.01081 162 REACTOME - Protein folding gene set www.pathwaycomm...
Null ATM mediated phosphorylation of repair proteins View Gene Set 0.001677 6 0.01142 163 REACTOME - ATM mediated phosphorylation of repair proteins gene set www.pathwaycomm...
Null ATM mediated response to DNA double-strand break View Gene Set 0.001677 6 0.01142 163 REACTOME - ATM mediated response to DNA double-strand break gene set www.pathwaycomm...
Null Regulation of beta-cell development View Gene Set 0.001789 110 0.01211 165 REACTOME - Regulation of beta-cell development gene set www.pathwaycomm...
Null mRNA Decay by 3' to 5' Exoribonuclease View Gene Set 0.001872 11 0.0126 166 REACTOME - mRNA Decay by 3' to 5' Exoribonuclease gene set www.pathwaycomm...
Null mRNA Decay by 5' to 3' Exoribonuclease View Gene Set 0.002096 13 0.01402 167 REACTOME - mRNA Decay by 5' to 3' Exoribonuclease gene set www.pathwaycomm...
Null Regulation of gene expression in beta cells View Gene Set 0.002226 100 0.0148 168 REACTOME - Regulation of gene expression in beta cells gene set www.pathwaycomm...
Null Metabolism of amino acids and derivatives View Gene Set 0.002376 201 0.01571 169 REACTOME - Metabolism of amino acids and derivatives gene set www.pathwaycomm...
Null Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components View Gene Set 0.00277 18 0.01809 170 REACTOME - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components gene set www.pathwaycomm...
Null Inactivation of APC/C via direct inhibition of the APC/C complex View Gene Set 0.00277 18 0.01809 170 REACTOME - Inactivation of APC/C via direct inhibition of the APC/C complex gene set www.pathwaycomm...
Null Kinesins View Gene Set 0.003161 22 0.02053 172 REACTOME - Kinesins gene set www.pathwaycomm...
Null Mitotic Spindle Checkpoint View Gene Set 0.003432 19 0.02216 173 REACTOME - Mitotic Spindle Checkpoint gene set www.pathwaycomm...
Null NS1 Mediated Effects on Host Pathways View Gene Set 0.003517 3 0.02258 174 REACTOME - NS1 Mediated Effects on Host Pathways gene set www.pathwaycomm...
Null Telomere C-strand (Lagging Strand) Synthesis View Gene Set 0.003576 22 0.02283 175 REACTOME - Telomere C-strand (Lagging Strand) Synthesis gene set www.pathwaycomm...
Null Pyrimidine metabolism View Gene Set 0.003635 23 0.02307 176 REACTOME - Pyrimidine metabolism gene set www.pathwaycomm...
Null PKB-mediated events View Gene Set 0.003726 28 0.02338 177 REACTOME - PKB-mediated events gene set www.pathwaycomm...
Null mTOR signalling View Gene Set 0.003726 28 0.02338 177 REACTOME - mTOR signalling gene set www.pathwaycomm...
Null Cyclin B2 mediated events View Gene Set 0.004528 5 0.02826 179 REACTOME - Cyclin B2 mediated events gene set www.pathwaycomm...
Null Glutathione synthesis View Gene Set 0.00469 3 0.02911 180 REACTOME - Glutathione synthesis gene set www.pathwaycomm...
Null Activation myristolyation of BID and translocation to mitochondria View Gene Set 0.004809 5 0.02956 181 REACTOME - Activation myristolyation of BID and translocation to mitochondria gene set www.pathwaycomm... myristolyation ...
Null APC-Cdc20 mediated degradation of Nek2A View Gene Set 0.004816 23 0.02956 181 REACTOME - APC-Cdc20 mediated degradation of Nek2A gene set www.pathwaycomm...
Null Host Interactions with Influenza Factors View Gene Set 0.004951 5 0.03022 183 REACTOME - Host Interactions with Influenza Factors gene set www.pathwaycomm...
Null Synthesis and interconversion of nucleotide di- and triphosphates View Gene Set 0.005029 16 0.03053 184 REACTOME - Synthesis and interconversion of nucleotide di- and triphosphates gene set www.pathwaycomm...
Null Mitochondrial transcription initiation View Gene Set 0.005083 3 0.03069 185 REACTOME - Mitochondrial transcription initiation gene set www.pathwaycomm...
Null Loss of proteins required for interphase microtubule organization from the centrosome View Gene Set 0.005265 62 0.03145 186 REACTOME - Loss of proteins required for interphase microtubule organization from the centrosome gene set www.pathwaycomm...
Null Loss of Nlp from mitotic centrosomes View Gene Set 0.005265 62 0.03145 186 REACTOME - Loss of Nlp from mitotic centrosomes gene set www.pathwaycomm...
Null Recruitment of repair and signaling proteins to double-strand breaks View Gene Set 0.005704 8 0.03389 188 REACTOME - Recruitment of repair and signaling proteins to double-strand breaks gene set www.pathwaycomm...
Null MRN complex relocalizes to nuclear foci View Gene Set 0.006096 4 0.03565 189 REACTOME - MRN complex relocalizes to nuclear foci gene set www.pathwaycomm...
Null Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks View Gene Set 0.006096 4 0.03565 189 REACTOME - Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks gene set www.pathwaycomm...
Null Metabolism of carbohydrates View Gene Set 0.006094 93 0.03565 189 REACTOME - Metabolism of carbohydrates gene set www.pathwaycomm...
Null TRAF6 mediated NF-kB activation View Gene Set 0.006303 16 0.03667 192 REACTOME - TRAF6 mediated NF-kB activation gene set www.pathwaycomm...
Null SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs View Gene Set 0.006851 11 0.03961 193 REACTOME - SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs gene set www.pathwaycomm...
Null Recycling of eIF2:GDP View Gene Set 0.006879 8 0.03961 193 REACTOME - Recycling of eIF2:GDP gene set www.pathwaycomm...
Null Base Excision Repair View Gene Set 0.00775 19 0.04417 195 REACTOME - Base Excision Repair gene set www.pathwaycomm...
Null Resolution of Abasic Sites (AP sites) View Gene Set 0.00775 19 0.04417 195 REACTOME - Resolution of Abasic Sites (AP sites) gene set www.pathwaycomm...
Null RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription View Gene Set 0.007861 93 0.04457 197 REACTOME - RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription gene set www.pathwaycomm... RNA Polymerase ... and Mitochondri...
Null Removal of DNA patch containing abasic residue View Gene Set 0.008111 17 0.04553 198 REACTOME - Removal of DNA patch containing abasic residue gene set www.pathwaycomm...
Null Resolution of AP sites via the multiple-nucleotide patch replacement pathway View Gene Set 0.008111 17 0.04553 198 REACTOME - Resolution of AP sites via the multiple-nucleotide patch replacement pathway gene set www.pathwaycomm...
Null Pentose phosphate pathway (hexose monophosphate shunt) View Gene Set 0.008414 6 0.04699 200 REACTOME - Pentose phosphate pathway (hexose monophosphate shunt) gene set www.pathwaycomm...

Gene Set Collection: mirbase.targets

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-146b-3p View Gene Set 2.745e-06 695 0.001951 1 microRNA targets for hsa-miR-146b-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-99b View Gene Set 6.942e-06 708 0.002468 2 microRNA targets for hsa-miR-99b from mirbase.targets www.mirbase.org...
Null hsa-miR-566 View Gene Set 1.743e-05 787 0.00413 3 microRNA targets for hsa-miR-566 from mirbase.targets www.mirbase.org...
Null hsa-miR-331-3p View Gene Set 6.032e-05 712 0.0082 4 microRNA targets for hsa-miR-331-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-658 View Gene Set 8.073e-05 660 0.0082 4 microRNA targets for hsa-miR-658 from mirbase.targets www.mirbase.org...
Null hsa-miR-671-5p View Gene Set 7.103e-05 813 0.0082 4 microRNA targets for hsa-miR-671-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-941 View Gene Set 4.886e-05 590 0.0082 4 microRNA targets for hsa-miR-941 from mirbase.targets www.mirbase.org...
Null hsa-miR-324-3p View Gene Set 0.0002184 788 0.01896 8 microRNA targets for hsa-miR-324-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-486-3p View Gene Set 0.00024 773 0.01896 8 microRNA targets for hsa-miR-486-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-383 View Gene Set 0.0003008 748 0.0196 10 microRNA targets for hsa-miR-383 from mirbase.targets www.mirbase.org...
Null hsa-miR-662 View Gene Set 0.0003032 663 0.0196 10 microRNA targets for hsa-miR-662 from mirbase.targets www.mirbase.org...
Null hsa-miR-378* View Gene Set 0.0003874 686 0.02119 12 microRNA targets for hsa-miR-378* from mirbase.targets www.mirbase.org...
Null hsa-miR-671-3p View Gene Set 0.0003649 767 0.02119 12 microRNA targets for hsa-miR-671-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-650 View Gene Set 0.000506 693 0.0257 14 microRNA targets for hsa-miR-650 from mirbase.targets www.mirbase.org...
Null hsa-miR-874 View Gene Set 0.0005968 722 0.02829 15 microRNA targets for hsa-miR-874 from mirbase.targets www.mirbase.org...
Null hsa-miR-181a-2* View Gene Set 0.0009014 742 0.04006 16 microRNA targets for hsa-miR-181a-2* from mirbase.targets www.mirbase.org...
Null hsa-miR-484 View Gene Set 0.0009601 733 0.04016 17 microRNA targets for hsa-miR-484 from mirbase.targets www.mirbase.org...
Null hsa-miR-323-5p View Gene Set 0.001056 763 0.0417 18 microRNA targets for hsa-miR-323-5p from mirbase.targets www.mirbase.org...

Gene Set Collection: miRNAtargetUnion

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null mirbase.mirtarget2.pictar.targetsUnion.hsa-miR-99b View Gene Set 1.936e-05 734 0.01493 1 microRNA targets for mirbase.mirtarget2.pictar.targetsUnion.hsa-miR-99b from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-99b View Gene Set 1.853e-05 744 0.01493 1 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-99b from miRNAtargetUnion www.mirbase.org...
Null mirbase.pictar.targetscan.targetsUnion.hsa-miR-99b View Gene Set 1.604e-05 744 0.01493 1 microRNA targets for mirbase.pictar.targetscan.targetsUnion.hsa-miR-99b from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-99b View Gene Set 0.0001017 806 0.03921 4 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-99b from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.pictar.targetsUnion.hsa-miR-99b View Gene Set 8.44e-05 808 0.03921 4 microRNA targets for miranda.mirbase.pictar.targetsUnion.hsa-miR-99b from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.targetscan.targetsUnion.hsa-miR-99b View Gene Set 9.216e-05 816 0.03921 4 microRNA targets for miranda.mirbase.targetscan.targetsUnion.hsa-miR-99b from miRNAtargetUnion www.mirbase.org...

Gene Set Collection: hprdBatch.UP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null T Cell Receptor Signaling Pathway View Gene Set 0.0004833 291 0.009666 1 From NetPath for T Cell Receptor Signaling Pathway www.netpath.org...

Gene Set Collection: hprdBatch.DIFFERENT

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null T Cell Receptor Signaling Pathway View Gene Set 0.002005 349 0.0401 1 From NetPath for T Cell Receptor Signaling Pathway www.netpath.org...

Gene Set Collection: hprdManual.UP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null TCR View Gene Set 5.904e-05 448 0.001417 1 From NetPath for TCR www.netpath.org...