Results

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Go to: Gene Set Collection: KEGG
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Go to: Gene Set Collection: Broad.c2.CP.REACTOME
Go to: Gene Set Collection: Broad.c3.TFT
Go to: Gene Set Collection: Broad.c4.CGN
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Go to: Gene Set Collection: Broad.c5.BP
Go to: Gene Set Collection: Broad.c5.CC
Go to: Gene Set Collection: Broad.c5.MF
Go to: Gene Set Collection: PMID
Go to: Gene Set Collection: Prosite
Go to: Gene Set Collection: Enzyme
Go to: Gene Set Collection: ppi.BIND
Go to: Gene Set Collection: ppi.BioGRID
Go to: Gene Set Collection: ppi.HPRD
Go to: Gene Set Collection: ppi.anyDB
Go to: Gene Set Collection: pathwayCommons.cell-map
Go to: Gene Set Collection: pathwayCommons.humancyc
Go to: Gene Set Collection: pathwayCommons.nci-nature
Go to: Gene Set Collection: pathwayCommons.reactome
Go to: Gene Set Collection: mirbase.targets
Go to: Gene Set Collection: hprdBatch.UP

AFA results for: tVPAda4DU

Click on the heading for any column to sort by that column.

Gene Set Collection: KEGG

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
KEGG 03040 View Gene Set 3.155e-25 128 6.751e-23 1 Spliceosome www.genome.jp/d...
KEGG 04110 View Gene Set 1.12e-10 128 1.198e-08 2 Cell cycle www.genome.jp/d...
KEGG 03050 View Gene Set 1.867e-10 48 1.332e-08 3 Proteasome www.genome.jp/d...
KEGG 03010 View Gene Set 2.59e-08 88 1.386e-06 4 Ribosome www.genome.jp/d...
KEGG 00240 View Gene Set 5.924e-08 99 2.536e-06 5 Pyrimidine metabolism www.genome.jp/d...
KEGG 03030 View Gene Set 6.501e-07 36 2.319e-05 6 DNA replication www.genome.jp/d...
KEGG 00970 View Gene Set 3.797e-06 41 0.0001161 7 Aminoacyl-tRNA biosynthesis www.genome.jp/d...
KEGG 03018 View Gene Set 6.78e-06 59 0.0001814 8 RNA degradation www.genome.jp/d...
KEGG 03440 View Gene Set 4.322e-05 28 0.001028 9 Homologous recombination www.genome.jp/d...
KEGG 03020 View Gene Set 0.0004432 29 0.009484 10 RNA polymerase www.genome.jp/d...
KEGG 04740 View Gene Set 0.0009458 388 0.0184 11 Olfactory transduction www.genome.jp/d...
KEGG 03410 View Gene Set 0.001117 34 0.01993 12 Base excision repair www.genome.jp/d...
KEGG 00670 View Gene Set 0.001608 17 0.02647 13 One carbon pool by folate www.genome.jp/d...
KEGG 03430 View Gene Set 0.002359 23 0.03605 14 Mismatch repair www.genome.jp/d...

Gene Set Collection: GO

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
GO GO:0044428 View Gene Set 1.112e-84 1938 1.486e-80 1 nuclear part amigo.geneontol...
GO GO:0031981 View Gene Set 8.208e-73 1518 5.483e-69 2 nuclear lumen amigo.geneontol...
GO GO:0005634 View Gene Set 2.8e-72 5198 1.247e-68 3 nucleus amigo.geneontol...
GO GO:0003676 View Gene Set 2.092e-70 2979 6.988e-67 4 nucleic acid binding amigo.geneontol...
GO GO:0070013 View Gene Set 4.372e-69 1845 1.168e-65 5 intracellular organelle lumen amigo.geneontol...
GO GO:0031974 View Gene Set 5.501e-66 1917 1.05e-62 6 membrane-enclosed lumen amigo.geneontol...
GO GO:0043233 View Gene Set 4.95e-66 1881 1.05e-62 6 organelle lumen amigo.geneontol...
GO GO:0006396 View Gene Set 1.7e-65 578 2.839e-62 8 RNA processing amigo.geneontol...
GO GO:0090304 View Gene Set 2.318e-63 3724 3.441e-60 9 nucleic acid metabolic process amigo.geneontol...
GO GO:0003723 View Gene Set 4.249e-59 732 5.677e-56 10 RNA binding amigo.geneontol...
GO GO:0010467 View Gene Set 8.222e-57 3806 9.986e-54 11 gene expression amigo.geneontol...
GO GO:0030529 View Gene Set 1.303e-56 504 1.45e-53 12 ribonucleoprotein complex amigo.geneontol...
GO GO:0006139 View Gene Set 6.058e-55 4294 6.226e-52 13 nucleobase nucleoside nucleotide and nucleic acid metabolic process amigo.geneontol...
GO GO:0034641 View Gene Set 6.555e-54 4584 6.255e-51 14 cellular nitrogen compound metabolic process amigo.geneontol...
GO GO:0044260 View Gene Set 4.272e-51 5699 3.805e-48 15 cellular macromolecule metabolic process amigo.geneontol...
GO GO:0006807 View Gene Set 9.835e-50 4698 8.212e-47 16 nitrogen compound metabolic process amigo.geneontol...
GO GO:0005654 View Gene Set 2.81e-45 939 2.208e-42 17 nucleoplasm amigo.geneontol...
GO GO:0043170 View Gene Set 4.012e-45 6274 2.978e-42 18 macromolecule metabolic process amigo.geneontol...
GO GO:0016070 View Gene Set 6.26e-45 2596 4.402e-42 19 RNA metabolic process amigo.geneontol...
GO GO:0008380 View Gene Set 3.968e-42 300 2.651e-39 20 RNA splicing amigo.geneontol...
GO GO:0016071 View Gene Set 1.94e-39 381 1.234e-36 21 mRNA metabolic process amigo.geneontol...
GO GO:0005730 View Gene Set 2.649e-39 734 1.609e-36 22 nucleolus amigo.geneontol...
GO GO:0006397 View Gene Set 5.174e-36 317 3.006e-33 23 mRNA processing amigo.geneontol...
GO GO:0022613 View Gene Set 1.855e-35 194 1.033e-32 24 ribonucleoprotein complex biogenesis amigo.geneontol...
GO GO:0009059 View Gene Set 3.365e-31 3597 1.665e-28 25 macromolecule biosynthetic process amigo.geneontol...
GO GO:0043228 View Gene Set 3.337e-31 2690 1.665e-28 25 non-membrane-bounded organelle amigo.geneontol...
GO GO:0043232 View Gene Set 3.337e-31 2690 1.665e-28 25 intracellular non-membrane-bounded organelle amigo.geneontol...
GO GO:0034645 View Gene Set 1.93e-30 3529 9.207e-28 28 cellular macromolecule biosynthetic process amigo.geneontol...
GO GO:0005694 View Gene Set 2.57e-30 507 1.184e-27 29 chromosome amigo.geneontol...
GO GO:0044249 View Gene Set 1.228e-27 4326 5.467e-25 30 cellular biosynthetic process amigo.geneontol...
GO GO:0044238 View Gene Set 2.883e-27 7629 1.242e-24 31 primary metabolic process amigo.geneontol...
GO GO:0009058 View Gene Set 1.024e-26 4436 4.25e-24 32 biosynthetic process amigo.geneontol...
GO GO:0044237 View Gene Set 1.05e-26 7431 4.25e-24 32 cellular metabolic process amigo.geneontol...
GO GO:0044451 View Gene Set 1.241e-26 600 4.876e-24 34 nucleoplasm part amigo.geneontol...
GO GO:0034660 View Gene Set 1.429e-26 236 5.457e-24 35 ncRNA metabolic process amigo.geneontol...
GO GO:0044427 View Gene Set 2.182e-26 420 8.098e-24 36 chromosomal part amigo.geneontol...
GO GO:0042254 View Gene Set 2.06e-25 130 7.437e-23 37 ribosome biogenesis amigo.geneontol...
GO GO:0022402 View Gene Set 4.023e-25 676 1.378e-22 38 cell cycle process amigo.geneontol...
GO GO:0005681 View Gene Set 4.021e-25 135 1.378e-22 38 spliceosomal complex amigo.geneontol...
GO GO:0032991 View Gene Set 6.036e-25 3237 2.016e-22 40 macromolecular complex amigo.geneontol...
GO GO:0006412 View Gene Set 7.05e-25 412 2.297e-22 41 translation amigo.geneontol...
GO GO:0051276 View Gene Set 1.034e-24 548 3.288e-22 42 chromosome organization amigo.geneontol...
GO GO:0000279 View Gene Set 1.453e-24 406 4.513e-22 43 M phase amigo.geneontol...
GO GO:0000775 View Gene Set 3.535e-24 146 1.073e-21 44 chromosome centromeric region amigo.geneontol...
GO GO:0000793 View Gene Set 3.841e-24 136 1.14e-21 45 condensed chromosome amigo.geneontol...
GO GO:0034470 View Gene Set 4.075e-24 193 1.183e-21 46 ncRNA processing amigo.geneontol...
GO GO:0000278 View Gene Set 1.723e-23 489 4.897e-21 47 mitotic cell cycle amigo.geneontol...
GO GO:0000375 View Gene Set 2.409e-22 106 6.706e-20 48 RNA splicing via transesterification reactions amigo.geneontol...
GO GO:0022403 View Gene Set 3.166e-22 522 8.632e-20 49 cell cycle phase amigo.geneontol...
GO GO:0007059 View Gene Set 3.303e-21 94 8.826e-19 50 chromosome segregation amigo.geneontol...
GO GO:0000377 View Gene Set 1.785e-20 97 4.586e-18 51 RNA splicing via transesterification reactions with bulged adenosine as nucleophile amigo.geneontol...
GO GO:0000398 View Gene Set 1.785e-20 97 4.586e-18 51 nuclear mRNA splicing via spliceosome amigo.geneontol...
GO GO:0005840 View Gene Set 3.17e-20 198 7.992e-18 53 ribosome amigo.geneontol...
GO GO:0003677 View Gene Set 3.844e-20 2028 9.51e-18 54 DNA binding amigo.geneontol...
GO GO:0000280 View Gene Set 5.732e-20 276 1.367e-17 55 nuclear division amigo.geneontol...
GO GO:0007067 View Gene Set 5.732e-20 276 1.367e-17 55 mitosis amigo.geneontol...
GO GO:0008152 View Gene Set 6.756e-20 8439 1.584e-17 57 metabolic process amigo.geneontol...
GO GO:0007049 View Gene Set 7.04e-20 1006 1.622e-17 58 cell cycle amigo.geneontol...
GO GO:0006259 View Gene Set 9.392e-20 592 2.127e-17 59 DNA metabolic process amigo.geneontol...
GO GO:0048285 View Gene Set 1.124e-19 286 2.502e-17 60 organelle fission amigo.geneontol...
GO GO:0000776 View Gene Set 2.252e-19 92 4.932e-17 61 kinetochore amigo.geneontol...
GO GO:0000087 View Gene Set 2.899e-19 286 6.248e-17 62 M phase of mitotic cell cycle amigo.geneontol...
GO GO:0016072 View Gene Set 4.847e-19 101 1.028e-16 63 rRNA metabolic process amigo.geneontol...
GO GO:0006364 View Gene Set 5.302e-19 97 1.107e-16 64 rRNA processing amigo.geneontol...
GO GO:0003735 View Gene Set 7.321e-18 158 1.505e-15 65 structural constituent of ribosome amigo.geneontol...
GO GO:0043227 View Gene Set 3.685e-17 8383 7.46e-15 66 membrane-bounded organelle amigo.geneontol...
GO GO:0000777 View Gene Set 4.983e-17 74 9.936e-15 67 condensed chromosome kinetochore amigo.geneontol...
GO GO:0043231 View Gene Set 5.536e-17 8376 1.088e-14 68 intracellular membrane-bounded organelle amigo.geneontol...
GO GO:0000779 View Gene Set 6.752e-17 79 1.307e-14 69 condensed chromosome centromeric region amigo.geneontol...
GO GO:0060255 View Gene Set 2.991e-16 3411 5.708e-14 70 regulation of macromolecule metabolic process amigo.geneontol...
GO GO:0016604 View Gene Set 3.196e-16 198 6.013e-14 71 nuclear body amigo.geneontol...
GO GO:0006350 View Gene Set 2.012e-15 2744 3.733e-13 72 transcription amigo.geneontol...
GO GO:0033279 View Gene Set 2.353e-15 121 4.307e-13 73 ribosomal subunit amigo.geneontol...
GO GO:0000819 View Gene Set 8.896e-15 38 1.606e-12 74 sister chromatid segregation amigo.geneontol...
GO GO:0031326 View Gene Set 1.054e-14 3048 1.878e-12 75 regulation of cellular biosynthetic process amigo.geneontol...
GO GO:0010468 View Gene Set 1.078e-14 2958 1.895e-12 76 regulation of gene expression amigo.geneontol...
GO GO:0010556 View Gene Set 1.171e-14 2901 2.031e-12 77 regulation of macromolecule biosynthetic process amigo.geneontol...
GO GO:0009889 View Gene Set 1.507e-14 3070 2.581e-12 78 regulation of biosynthetic process amigo.geneontol...
GO GO:0006974 View Gene Set 1.78e-14 412 3.01e-12 79 response to DNA damage stimulus amigo.geneontol...
GO GO:0000070 View Gene Set 2.16e-14 37 3.607e-12 80 mitotic sister chromatid segregation amigo.geneontol...
GO GO:0006281 View Gene Set 2.223e-14 309 3.667e-12 81 DNA repair amigo.geneontol...
GO GO:0005819 View Gene Set 2.89e-14 167 4.709e-12 82 spindle amigo.geneontol...
GO GO:0022618 View Gene Set 3.736e-14 76 6.014e-12 83 ribonucleoprotein complex assembly amigo.geneontol...
GO GO:0006403 View Gene Set 3.934e-14 104 6.256e-12 84 RNA localization amigo.geneontol...
GO GO:0007051 View Gene Set 6.942e-14 57 1.091e-11 85 spindle organization amigo.geneontol...
GO GO:0050657 View Gene Set 7.811e-14 102 1.186e-11 86 nucleic acid transport amigo.geneontol...
GO GO:0050658 View Gene Set 7.811e-14 102 1.186e-11 86 RNA transport amigo.geneontol...
GO GO:0051236 View Gene Set 7.811e-14 102 1.186e-11 86 establishment of RNA localization amigo.geneontol...
GO GO:0043229 View Gene Set 8.697e-14 9346 1.306e-11 89 intracellular organelle amigo.geneontol...
GO GO:0043226 View Gene Set 1.526e-13 9360 2.265e-11 90 organelle amigo.geneontol...
GO GO:0006260 View Gene Set 2.727e-13 239 4.004e-11 91 DNA replication amigo.geneontol...
GO GO:0015931 View Gene Set 4.758e-13 118 6.909e-11 92 nucleobase nucleoside nucleotide and nucleic acid transport amigo.geneontol...
GO GO:0044085 View Gene Set 5.156e-13 1167 7.329e-11 93 cellular component biogenesis amigo.geneontol...
GO GO:0080090 View Gene Set 5.114e-13 3585 7.329e-11 93 regulation of primary metabolic process amigo.geneontol...
GO GO:0044446 View Gene Set 6.031e-13 5019 8.482e-11 95 intracellular organelle part amigo.geneontol...
GO GO:0006325 View Gene Set 8.107e-13 425 1.128e-10 96 chromatin organization amigo.geneontol...
GO GO:0051439 View Gene Set 2.072e-12 68 2.854e-10 97 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0044422 View Gene Set 2.756e-12 5089 3.758e-10 98 organelle part amigo.geneontol...
GO GO:0006996 View Gene Set 3.692e-12 1501 4.982e-10 99 organelle organization amigo.geneontol...
GO GO:0034621 View Gene Set 3.929e-12 458 5.249e-10 100 cellular macromolecular complex subunit organization amigo.geneontol...
GO GO:0031323 View Gene Set 6.151e-12 3768 8.136e-10 101 regulation of cellular metabolic process amigo.geneontol...
GO GO:0045449 View Gene Set 6.276e-12 2647 8.22e-10 102 regulation of transcription amigo.geneontol...
GO GO:0031145 View Gene Set 8.16e-12 64 1.038e-09 103 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0000502 View Gene Set 8.131e-12 63 1.038e-09 103 proteasome complex amigo.geneontol...
GO GO:0000166 View Gene Set 8.073e-12 2257 1.038e-09 103 nucleotide binding amigo.geneontol...
GO GO:0034622 View Gene Set 8.668e-12 393 1.092e-09 106 cellular macromolecular complex assembly amigo.geneontol...
GO GO:0051437 View Gene Set 8.743e-12 64 1.092e-09 106 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0071103 View Gene Set 1.258e-11 140 1.556e-09 108 DNA conformation change amigo.geneontol...
GO GO:0051436 View Gene Set 1.286e-11 62 1.576e-09 109 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0004386 View Gene Set 2.203e-11 144 2.676e-09 110 helicase activity amigo.geneontol...
GO GO:0051171 View Gene Set 2.288e-11 3066 2.754e-09 111 regulation of nitrogen compound metabolic process amigo.geneontol...
GO GO:0019219 View Gene Set 2.749e-11 3040 3.279e-09 112 regulation of nucleobase nucleoside nucleotide and nucleic acid metabolic process amigo.geneontol...
GO GO:0051352 View Gene Set 2.897e-11 66 3.395e-09 113 negative regulation of ligase activity amigo.geneontol...
GO GO:0051444 View Gene Set 2.897e-11 66 3.395e-09 113 negative regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0051028 View Gene Set 3.663e-11 90 4.255e-09 115 mRNA transport amigo.geneontol...
GO GO:0031397 View Gene Set 4.956e-11 78 5.708e-09 116 negative regulation of protein ubiquitination amigo.geneontol...
GO GO:0000226 View Gene Set 5.744e-11 178 6.559e-09 117 microtubule cytoskeleton organization amigo.geneontol...
GO GO:0006399 View Gene Set 7.255e-11 118 8.214e-09 118 tRNA metabolic process amigo.geneontol...
GO GO:0000228 View Gene Set 1.127e-10 177 1.265e-08 119 nuclear chromosome amigo.geneontol...
GO GO:0051443 View Gene Set 1.791e-10 71 1.961e-08 120 positive regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0008026 View Gene Set 1.784e-10 105 1.961e-08 120 ATP-dependent helicase activity amigo.geneontol...
GO GO:0070035 View Gene Set 1.784e-10 105 1.961e-08 120 purine NTP-dependent helicase activity amigo.geneontol...
GO GO:0051351 View Gene Set 1.917e-10 74 2.082e-08 123 positive regulation of ligase activity amigo.geneontol...
GO GO:0019222 View Gene Set 2.54e-10 4060 2.737e-08 124 regulation of metabolic process amigo.geneontol...
GO GO:0015934 View Gene Set 2.752e-10 64 2.941e-08 125 large ribosomal subunit amigo.geneontol...
GO GO:0005488 View Gene Set 4.293e-10 12334 4.552e-08 126 binding amigo.geneontol...
GO GO:0046930 View Gene Set 5.35e-10 85 5.628e-08 127 pore complex amigo.geneontol...
GO GO:0051340 View Gene Set 5.527e-10 85 5.724e-08 128 regulation of ligase activity amigo.geneontol...
GO GO:0000922 View Gene Set 5.519e-10 63 5.724e-08 128 spindle pole amigo.geneontol...
GO GO:0051438 View Gene Set 5.581e-10 82 5.735e-08 130 regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0016568 View Gene Set 9.098e-10 324 9.208e-08 131 chromatin modification amigo.geneontol...
GO GO:0051301 View Gene Set 9.069e-10 358 9.208e-08 131 cell division amigo.geneontol...
GO GO:0006261 View Gene Set 9.965e-10 74 1.001e-07 133 DNA-dependent DNA replication amigo.geneontol...
GO GO:0016607 View Gene Set 1.434e-09 116 1.43e-07 134 nuclear speck amigo.geneontol...
GO GO:0005643 View Gene Set 1.583e-09 71 1.567e-07 135 nuclear pore amigo.geneontol...
GO GO:0000794 View Gene Set 2.609e-09 52 2.563e-07 136 condensed nuclear chromosome amigo.geneontol...
GO GO:0000313 View Gene Set 2.858e-09 49 2.767e-07 137 organellar ribosome amigo.geneontol...
GO GO:0005761 View Gene Set 2.858e-09 49 2.767e-07 137 mitochondrial ribosome amigo.geneontol...
GO GO:0050000 View Gene Set 3.481e-09 17 3.322e-07 139 chromosome localization amigo.geneontol...
GO GO:0051303 View Gene Set 3.481e-09 17 3.322e-07 139 establishment of chromosome localization amigo.geneontol...
GO GO:0008168 View Gene Set 3.814e-09 176 3.614e-07 141 methyltransferase activity amigo.geneontol...
GO GO:0008135 View Gene Set 4.357e-09 86 4.099e-07 142 translation factor activity nucleic acid binding amigo.geneontol...
GO GO:0065003 View Gene Set 5.557e-09 763 5.192e-07 143 macromolecular complex assembly amigo.geneontol...
GO GO:0016741 View Gene Set 6.641e-09 179 6.162e-07 144 transferase activity transferring one-carbon groups amigo.geneontol...
GO GO:0005876 View Gene Set 6.889e-09 35 6.348e-07 145 spindle microtubule amigo.geneontol...
GO GO:0000387 View Gene Set 8.029e-09 31 7.347e-07 146 spliceosomal snRNP assembly amigo.geneontol...
GO GO:0044424 View Gene Set 9.804e-09 10976 8.91e-07 147 intracellular part amigo.geneontol...
GO GO:0006323 View Gene Set 1.038e-08 119 9.368e-07 148 DNA packaging amigo.geneontol...
GO GO:0043933 View Gene Set 1.147e-08 836 1.028e-06 149 macromolecular complex subunit organization amigo.geneontol...
GO GO:0015030 View Gene Set 1.33e-08 43 1.185e-06 150 Cajal body amigo.geneontol...
GO GO:0032559 View Gene Set 1.521e-08 1503 1.346e-06 151 adenyl ribonucleotide binding amigo.geneontol...
GO GO:0006414 View Gene Set 1.691e-08 104 1.486e-06 152 translational elongation amigo.geneontol...
GO GO:0032774 View Gene Set 2.143e-08 1953 1.871e-06 153 RNA biosynthetic process amigo.geneontol...
GO GO:0005524 View Gene Set 2.195e-08 1480 1.904e-06 154 ATP binding amigo.geneontol...
GO GO:0006351 View Gene Set 2.712e-08 1949 2.337e-06 155 transcription DNA-dependent amigo.geneontol...
GO GO:0030554 View Gene Set 3.062e-08 1584 2.622e-06 156 adenyl nucleotide binding amigo.geneontol...
GO GO:0000785 View Gene Set 4.034e-08 213 3.433e-06 157 chromatin amigo.geneontol...
GO GO:0005759 View Gene Set 4.438e-08 223 3.729e-06 158 mitochondrial matrix amigo.geneontol...
GO GO:0031980 View Gene Set 4.438e-08 223 3.729e-06 158 mitochondrial lumen amigo.geneontol...
GO GO:0051310 View Gene Set 5.256e-08 13 4.38e-06 160 metaphase plate congression amigo.geneontol...
GO GO:0051321 View Gene Set 5.278e-08 115 4.38e-06 160 meiotic cell cycle amigo.geneontol...
GO GO:0006405 View Gene Set 6.24e-08 44 5.146e-06 162 RNA export from nucleus amigo.geneontol...
GO GO:0022626 View Gene Set 6.788e-08 75 5.564e-06 163 cytosolic ribosome amigo.geneontol...
GO GO:0007126 View Gene Set 7.377e-08 113 5.973e-06 164 meiosis amigo.geneontol...
GO GO:0051327 View Gene Set 7.377e-08 113 5.973e-06 164 M phase of meiotic cell cycle amigo.geneontol...
GO GO:0030532 View Gene Set 7.458e-08 32 6.003e-06 166 small nuclear ribonucleoprotein complex amigo.geneontol...
GO GO:0000075 View Gene Set 8.333e-08 109 6.666e-06 167 cell cycle checkpoint amigo.geneontol...
GO GO:0006310 View Gene Set 9.308e-08 130 7.402e-06 168 DNA recombination amigo.geneontol...
GO GO:0006473 View Gene Set 9.391e-08 61 7.424e-06 169 protein amino acid acetylation amigo.geneontol...
GO GO:0000245 View Gene Set 9.928e-08 34 7.802e-06 170 spliceosome assembly amigo.geneontol...
GO GO:0010498 View Gene Set 1.126e-07 166 8.8e-06 171 proteasomal protein catabolic process amigo.geneontol...
GO GO:0003682 View Gene Set 1.137e-07 178 8.828e-06 172 chromatin binding amigo.geneontol...
GO GO:0005622 View Gene Set 1.477e-07 11329 1.14e-05 173 intracellular amigo.geneontol...
GO GO:0003743 View Gene Set 1.616e-07 52 1.241e-05 174 translation initiation factor activity amigo.geneontol...
GO GO:0015935 View Gene Set 1.847e-07 59 1.41e-05 175 small ribosomal subunit amigo.geneontol...
GO GO:0051168 View Gene Set 1.968e-07 71 1.494e-05 176 nuclear export amigo.geneontol...
GO GO:0031023 View Gene Set 2.021e-07 41 1.525e-05 177 microtubule organizing center organization amigo.geneontol...
GO GO:0043566 View Gene Set 2.346e-07 149 1.761e-05 178 structure-specific DNA binding amigo.geneontol...
GO GO:0043161 View Gene Set 2.516e-07 162 1.878e-05 179 proteasomal ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0000123 View Gene Set 2.637e-07 50 1.957e-05 180 histone acetyltransferase complex amigo.geneontol...
GO GO:0001882 View Gene Set 2.749e-07 1630 2.029e-05 181 nucleoside binding amigo.geneontol...
GO GO:0031398 View Gene Set 2.886e-07 95 2.119e-05 182 positive regulation of protein ubiquitination amigo.geneontol...
GO GO:0004527 View Gene Set 3.534e-07 57 2.58e-05 183 exonuclease activity amigo.geneontol...
GO GO:0031396 View Gene Set 4.836e-07 121 3.512e-05 184 regulation of protein ubiquitination amigo.geneontol...
GO GO:0007080 View Gene Set 4.89e-07 11 3.532e-05 185 mitotic metaphase plate congression amigo.geneontol...
GO GO:0044454 View Gene Set 4.987e-07 139 3.582e-05 186 nuclear chromosome part amigo.geneontol...
GO GO:0043543 View Gene Set 5.366e-07 72 3.834e-05 187 protein amino acid acylation amigo.geneontol...
GO GO:0003697 View Gene Set 5.422e-07 58 3.853e-05 188 single-stranded DNA binding amigo.geneontol...
GO GO:0044265 View Gene Set 5.72e-07 479 4.043e-05 189 cellular macromolecule catabolic process amigo.geneontol...
GO GO:0001883 View Gene Set 5.824e-07 1620 4.095e-05 190 purine nucleoside binding amigo.geneontol...
GO GO:0051297 View Gene Set 6.085e-07 40 4.256e-05 191 centrosome organization amigo.geneontol...
GO GO:0008033 View Gene Set 6.52e-07 78 4.537e-05 192 tRNA processing amigo.geneontol...
GO GO:0007052 View Gene Set 6.577e-07 22 4.553e-05 193 mitotic spindle organization amigo.geneontol...
GO GO:0016573 View Gene Set 7.036e-07 56 4.845e-05 194 histone acetylation amigo.geneontol...
GO GO:0000184 View Gene Set 7.481e-07 30 5.125e-05 195 nuclear-transcribed mRNA catabolic process nonsense-mediated decay amigo.geneontol...
GO GO:0004518 View Gene Set 7.691e-07 161 5.242e-05 196 nuclease activity amigo.geneontol...
GO GO:0033554 View Gene Set 8.414e-07 698 5.706e-05 197 cellular response to stress amigo.geneontol...
GO GO:0005739 View Gene Set 8.757e-07 1274 5.909e-05 198 mitochondrion amigo.geneontol...
GO GO:0003729 View Gene Set 8.993e-07 71 6.037e-05 199 mRNA binding amigo.geneontol...
GO GO:0016569 View Gene Set 1.037e-06 165 6.926e-05 200 covalent chromatin modification amigo.geneontol...

Gene Set Collection: Broad.c2.CGP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad PUJANA_BRCA1_PCC_NETWORK View Gene Set 5.821e-88 1582 1.392e-84 1 Genes constituting the BRCA1-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA1 [Gene ID=672] across a compendium of normal tissues. www.broad.mit.e...
Broad PUJANA_CHEK2_PCC_NETWORK View Gene Set 8.406e-87 744 1.005e-83 2 Genes constituting the CHEK2-PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient PCC >= 0.4) with that of CHEK2 [Gene ID=11200]. www.broad.mit.e...
Broad DODD_NASOPHARYNGEAL_CARCINOMA_DN View Gene Set 2.815e-75 1253 2.245e-72 3 Genes down-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. www.broad.mit.e...
Broad CAIRO_HEPATOBLASTOMA_CLASSES_UP View Gene Set 3.176e-66 577 1.899e-63 4 Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). www.broad.mit.e...
Broad KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP View Gene Set 1.946e-64 1180 9.31e-62 5 Genes up-regulated in TC71 and EWS502 cells (Ewing's sarcoma) upon knockdown of the EWSR1-FLII fusion [Gene ID=2130 2314]. www.broad.mit.e...
Broad MANALO_HYPOXIA_DN View Gene Set 1.327e-61 276 5.292e-59 6 Genes down-regulated in response to both hypoxia and overexpression of an active form of HIF1A [Gene ID=3091]. www.broad.mit.e...
Broad PUJANA_BRCA2_PCC_NETWORK View Gene Set 1.274e-44 410 4.355e-42 7 Genes constituting the BRCA2-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA2 [Gene ID=675] across a compendium of normal tissues. www.broad.mit.e...
Broad WONG_EMBRYONIC_STEM_CELL_CORE View Gene Set 7.568e-40 331 2.263e-37 8 The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module. www.broad.mit.e...
Broad WEI_MYCN_TARGETS_WITH_E_BOX View Gene Set 2.35e-39 757 6.247e-37 9 Genes whose promoters contain E-box motifs and whose expression changed in MYCN-3 cells (neuroblastoma) upon induction of MYCN [Gene ID=4613]. www.broad.mit.e...
Broad SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP View Gene Set 3.53e-39 143 8.444e-37 10 Up-regulated genes whose expression correlated with histologic grade of invasive breast cancer tumors: comparison of grade 1 vs grade 3. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN View Gene Set 4.589e-39 920 9.978e-37 11 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h. www.broad.mit.e...
Broad BERENJENO_TRANSFORMED_BY_RHOA_UP View Gene Set 3.869e-36 485 7.712e-34 12 Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [Gene ID=387] off plasmid vector. www.broad.mit.e...
Broad ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER View Gene Set 2.489e-35 138 4.557e-33 13 The 'Cervical Cancer Proliferation Cluster' (CCPC): genes whose expression in cervical carcinoma positively correlates with that of the HPV E6 and E7 oncogenes; they are also differentially expressed according to disease outcome. www.broad.mit.e...
Broad SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 View Gene Set 2.667e-35 435 4.557e-33 13 Cluster 6 of method A: up-regulation of these genes in patients with non???small cell lung cancer (NSCLC) predicts poor survival outcome. www.broad.mit.e...
Broad KOBAYASHI_EGFR_SIGNALING_24HR_DN View Gene Set 5.565e-32 243 8.874e-30 15 Genes down-regulated in H1975 cells (non-small cell lung cancer NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 24h. www.broad.mit.e...
Broad PUJANA_XPRSS_INT_NETWORK View Gene Set 1.272e-30 164 1.902e-28 16 Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200] in a compendium of normal tissues. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP View Gene Set 1.141e-28 589 1.605e-26 17 Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. www.broad.mit.e...
Broad MUELLER_PLURINET View Gene Set 4.374e-28 294 5.813e-26 18 Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells embryonical carcinomas and induced pluripotent cells). www.broad.mit.e...
Broad PUJANA_ATM_PCC_NETWORK View Gene Set 1.988e-27 1375 2.502e-25 19 Genes constituting the ATM-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of ATM [Gene ID=472] across a compendium of normal tissues. www.broad.mit.e...
Broad CROONQUIST_IL6_DEPRIVATION_DN View Gene Set 5.057e-27 80 6.048e-25 20 Genes down-regulated in the ANBL-6 cell line (multiple myeloma MM) after withdrawal of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad BIDUS_METASTASIS_UP View Gene Set 1.289e-25 203 1.468e-23 21 Genes up-regulated in endometroid endometrial tumors from patients with lymph node metastases compared to those without the metastases. www.broad.mit.e...
Broad GARY_CD5_TARGETS_DN View Gene Set 7.36e-25 415 8.003e-23 22 Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. www.broad.mit.e...
Broad BENPORATH_CYCLING_GENES View Gene Set 8.881e-25 630 9.236e-23 23 Genes showing cell-cycle stage-specific expression [PMID=12058064]. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN View Gene Set 9.675e-25 832 9.643e-23 24 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. www.broad.mit.e...
Broad PUJANA_BRCA_CENTERED_NETWORK View Gene Set 8.527e-24 92 8.158e-22 25 Genes constituting the BRCA-centered network (BCN). www.broad.mit.e...
Broad WINNEPENNINCKX_MELANOMA_METASTASIS_UP View Gene Set 9.587e-24 152 8.82e-22 26 Genes from the 254-gene classifier which were up-regulated in melanoma patients with a reported distant metastasis within 4 years. www.broad.mit.e...
Broad CROONQUIST_NRAS_SIGNALING_DN View Gene Set 9.353e-23 62 8.286e-21 27 Genes down-regulated in ANBL-6 cell line (multiple myeloma MM) expressing a constantly active form of NRAS [Gene ID=4893] off a plasmid vector compared to those grown in the presence of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad MISSIAGLIA_REGULATED_BY_METHYLATION_DN View Gene Set 5.236e-22 96 4.473e-20 28 Genes down-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668] a DNA hypomethylating agent similar to azacitidine [PubChem=9444]. www.broad.mit.e...
Broad GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP View Gene Set 8.678e-22 180 7.158e-20 29 Genes up-regulated in quiescent CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors compared to the dividing cells from CML (chronic myeloid leukemia) patients. www.broad.mit.e...
Broad KANG_DOXORUBICIN_RESISTANCE_UP View Gene Set 2e-21 53 1.594e-19 30 Genes differentialy expressed in gastric cancer cell lines: doxorubicin [PubChem=31703] resistant vs sensitive. www.broad.mit.e...
Broad FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP View Gene Set 2.071e-21 144 1.598e-19 31 Genes up-regulated in genomically unstable Ewing's sarcoma tumors compared to the stable ones. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP View Gene Set 2.646e-21 184 1.978e-19 32 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G3 defined by unsupervised clustering. www.broad.mit.e...
Broad TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C View Gene Set 6.237e-21 436 4.521e-19 33 Genes down-regulated in HCT116 cells (colon cancer) upon expression of MIR34B or MIR34C [Gene ID=407041 407042] microRNAs. www.broad.mit.e...
Broad WHITEFORD_PEDIATRIC_CANCER_MARKERS View Gene Set 6.74e-21 92 4.742e-19 34 Differentially expressed genes in a panel of xenografts representing 8 common pediatric tumors compared to the normal tissues. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM View Gene Set 1.974e-20 154 1.349e-18 35 Cluster 7: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] and down-regulated by the combination of MYC and serum. www.broad.mit.e...
Broad MARKEY_RB1_ACUTE_LOF_DN View Gene Set 2.87e-20 201 1.907e-18 36 Genes down-regulated in adult fibroblasts with inactivated RB1 [Gene ID=5925] by Cre-lox: acute loss of function (LOF) of RB1. www.broad.mit.e...
Broad VECCHI_GASTRIC_CANCER_EARLY_UP View Gene Set 1.593e-19 408 1.03e-17 37 Up-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. www.broad.mit.e...
Broad GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN View Gene Set 7.757e-19 86 4.883e-17 38 Genes down-regulated in quiescent vs dividing CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors. www.broad.mit.e...
Broad MITSIADES_RESPONSE_TO_APLIDIN_DN View Gene Set 3.035e-18 241 1.862e-16 39 Genes down-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164] a marine-derived compound with potential anti-cancer properties. www.broad.mit.e...
Broad BENPORATH_PROLIFERATION View Gene Set 1.841e-17 140 1.101e-15 40 Set 'Proliferation Cluster': genes defined in human breast tumor expression data. www.broad.mit.e...
Broad CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN View Gene Set 2.538e-17 639 1.481e-15 41 Genes down-regulated in APL (acute promyeolocytic leukemia) blasts expressing PML-RARA fusion [Gene ID=5371 5914] compared to normal promyeloblasts. www.broad.mit.e...
Broad LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN View Gene Set 2.942e-17 158 1.675e-15 42 Genes down-regulated in Wilm's tumor samples compared to fetal kidney. www.broad.mit.e...
Broad FOURNIER_ACINAR_DEVELOPMENT_LATE_2 View Gene Set 3.317e-17 265 1.845e-15 43 Genes identified by method 2 as coordinately down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro. www.broad.mit.e...
Broad HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP View Gene Set 4.471e-17 93 2.43e-15 44 Genes up-regulated during differentiation from large pre-BII to small pre-BII lymphocyte. www.broad.mit.e...
Broad BLUM_RESPONSE_TO_SALIRASIB_DN View Gene Set 4.983e-17 332 2.649e-15 45 Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [Gene ID=3265]. www.broad.mit.e...
Broad TARTE_PLASMA_CELL_VS_PLASMABLAST_DN View Gene Set 5.278e-17 303 2.744e-15 46 Genes down-regulated in mature plasma cells compared with plasmablastic B lymphocytes. www.broad.mit.e...
Broad DANG_MYC_TARGETS_UP View Gene Set 8.306e-17 127 4.227e-15 47 Genes up-regulated by MYC [Gene ID=4609] and whose promoters are bound by MYC according to MYC Target Gene Database. www.broad.mit.e...
Broad FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN View Gene Set 1.123e-16 43 5.597e-15 48 Genes down-regulated in MCF-7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4-hydroxytamoxifen raloxifene or ICI 182780 but not by estradiol [PubChem=44959 5035 3478439 5757]. www.broad.mit.e...
Broad ODONNELL_TFRC_TARGETS_DN View Gene Set 2.266e-16 131 1.106e-14 49 Genes dpwn-regulated in P493-6 cells (B lymphocyte) upon knockdown of TFRC [Gene ID=7037] by RNAi. www.broad.mit.e...
Broad GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN View Gene Set 9.962e-16 148 4.766e-14 50 Genes down-regulated in the A673 cells (Ewing sarcoma) after double knockdown of both FLI1 and DAX1 [Gene ID=2313 190] by RNAi. www.broad.mit.e...
Broad BASAKI_YBX1_TARGETS_UP View Gene Set 5.04e-15 279 2.364e-13 51 Genes up-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [Gene ID=4904] knockdown by RNAi. www.broad.mit.e...
Broad HORIUCHI_WTAP_TARGETS_DN View Gene Set 5.522e-15 289 2.54e-13 52 Genes down-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [Gene ID=9589] by RNAi. www.broad.mit.e...
Broad AMUNDSON_GAMMA_RADIATION_RESPONSE View Gene Set 3.262e-14 36 1.472e-12 53 Genes down-regulated across the entire panel of NCI-60 cell lines in response to gamma radiation. www.broad.mit.e...
Broad FUJII_YBX1_TARGETS_DN View Gene Set 4.248e-14 139 1.882e-12 54 Genes down-regulated in MCF-7 cells (breast cancer) after knockdown of YBX1 [Gene ID=4904] by RNAi. www.broad.mit.e...
Broad ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN View Gene Set 6.574e-14 42 2.859e-12 55 Genes down-regulated in P493-6 cells (B lymphocyte) by MYC [Gene ID=4609] and up-regulated by RNAi knockdown of TFRC [Gene ID=7037]. www.broad.mit.e...
Broad FARMER_BREAST_CANCER_CLUSTER_2 View Gene Set 7.391e-14 33 3.157e-12 56 Cluster 2: selected proliferation and 8q amplicon genes clustered together across breast cancer samples. www.broad.mit.e...
Broad GRADE_COLON_CANCER_UP View Gene Set 8.368e-14 711 3.512e-12 57 Up-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples. www.broad.mit.e...
Broad PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP View Gene Set 2.428e-13 53 1.001e-11 58 The XPRSS-Int network genes up-regulated in breast tumors from patients with germline mutations in BRCA1 [Gene ID=672] compared to those with the wild type allele. www.broad.mit.e...
Broad ZHAN_MULTIPLE_MYELOMA_PR_UP View Gene Set 4.06e-13 43 1.646e-11 59 Top 50 up-regulated genes in cluster PR of multiple myeloma samples characterized by increased expression of proliferation and cell cycle genes. www.broad.mit.e...
Broad CHANG_CYCLING_GENES View Gene Set 7.11e-13 49 2.834e-11 60 Fibroblast serum response genes showing periodic expression during the cell cycle; excluded from the core serum response signature. www.broad.mit.e...
Broad LY_AGING_OLD_DN View Gene Set 1.599e-11 47 6.268e-10 61 Genes up-regulated in fibroblasts from old individuals compared to those from young donors. www.broad.mit.e...
Broad MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN View Gene Set 1.946e-11 53 7.508e-10 62 Genes commonly down-regulated in SK-N-BE cells (neuroblastoma) after RNAi knockdown of CCND1 and CDK4 [Gene ID=595 1019]. www.broad.mit.e...
Broad MORI_LARGE_PRE_BII_LYMPHOCYTE_UP View Gene Set 2.386e-11 52 9.058e-10 63 Up-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Large Pre-BII stage. www.broad.mit.e...
Broad FURUKAWA_DUSP6_TARGETS_PCI35_DN View Gene Set 2.803e-11 66 1.04e-09 64 Genes down-regulated in PCI-35 cells (pancreatic cancer lack endogenous DUSP6 [Gene ID=1848]) upon expression of DUSP6 off an adenoviral vector. www.broad.mit.e...
Broad ZHANG_BREAST_CANCER_PROGENITORS_UP View Gene Set 2.825e-11 370 1.04e-09 64 Genes changed in cancer stem cells isolated from mammary tumors compared to the non-tumorigenic cells. www.broad.mit.e...
Broad REN_BOUND_BY_E2F View Gene Set 3.738e-11 47 1.355e-09 66 Genes whose promoters were bound by E2F1 [Gene ID=1869] and E2F4 [Gene ID=1874] in the primary fibroblasts WI-38 by ChIP on chip assay. www.broad.mit.e...
Broad LINDGREN_BLADDER_CANCER_CLUSTER_3_UP View Gene Set 4.368e-11 314 1.559e-09 67 Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors. www.broad.mit.e...
Broad GRADE_COLON_AND_RECTAL_CANCER_UP View Gene Set 4.459e-11 213 1.568e-09 68 Up-regulated genes in both rectal and colon carcinoma compared to normal mucosa samples. www.broad.mit.e...
Broad KAUFFMANN_DNA_REPAIR_GENES View Gene Set 4.936e-11 205 1.711e-09 69 Genes involved in DNA repair compiled manually by the authors. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_24HR_UP View Gene Set 6.839e-11 537 2.337e-09 70 Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h. www.broad.mit.e...
Broad DANG_BOUND_BY_MYC View Gene Set 1.029e-10 1045 3.467e-09 71 Genes whose promoters are bound by MYC [Gene ID=4609] according to MYC Target Gene Database. www.broad.mit.e...
Broad NUYTTEN_EZH2_TARGETS_DN View Gene Set 1.289e-10 859 4.283e-09 72 Genes down-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [Gene ID=2146] by RNAi. www.broad.mit.e...
Broad KAUFFMANN_MELANOMA_RELAPSE_UP View Gene Set 1.456e-10 57 4.772e-09 73 DNA repair and replication genes up-regulated in melanoma patients who will relapse vs patients who will not. www.broad.mit.e...
Broad MORI_IMMATURE_B_LYMPHOCYTE_DN View Gene Set 1.635e-10 52 5.285e-09 74 Down-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the immature B stage. www.broad.mit.e...
Broad BENPORATH_ES_1 View Gene Set 2.196e-10 367 7.002e-09 75 Set 'ES exp1': genes overexpressed in human embryonic stem cells according to 5 or more out of 20 profiling studies. www.broad.mit.e...
Broad KAUFFMANN_DNA_REPLICATION_GENES View Gene Set 2.35e-10 128 7.397e-09 76 Genes involved in DNA replication compiled manually by the authors. www.broad.mit.e...
Broad CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP View Gene Set 2.72e-10 135 8.451e-09 77 Genes up-regulated in CD4+ [Gene ID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]. www.broad.mit.e...
Broad EGUCHI_CELL_CYCLE_RB1_TARGETS View Gene Set 1.15e-09 19 3.512e-08 78 RB1 [Gene ID=5925] target genes involved in cell cycle regulation: genes down-regulated by doxorubicin [PubChem=31703] only in cells expressing RB1. www.broad.mit.e...
Broad PAL_PRMT5_TARGETS_UP View Gene Set 1.16e-09 178 3.512e-08 78 Genes up-regulated in NIH-3T3 cells (fibroblast) after knockdown of PRMT5 [Gene ID=10419] by RNAi. www.broad.mit.e...
Broad RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN View Gene Set 1.326e-09 351 3.965e-08 80 Genes down-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids. www.broad.mit.e...
Broad RUIZ_TNC_TARGETS_DN View Gene Set 1.451e-09 138 4.285e-08 81 Genes down-regulated in T98G cells (glioblastoma) by TNC [Gene ID=3371]. www.broad.mit.e...
Broad WELCSH_BRCA1_TARGETS_1_DN View Gene Set 1.722e-09 124 5.022e-08 82 Upregulated by induction of exogenous BRCA1 in EcR-293 cells www.broad.mit.e...
Broad PENG_GLUTAMINE_DEPRIVATION_DN View Gene Set 2.845e-09 84 8.199e-08 83 Genes down-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation. www.broad.mit.e...
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN View Gene Set 3.805e-09 51 1.084e-07 84 Genes from the turquoise module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphocholine (oxPAPC). www.broad.mit.e...
Broad RIZ_ERYTHROID_DIFFERENTIATION View Gene Set 4.967e-09 71 1.398e-07 85 Selected gradually up-regulated genes in the TLX1 [Gene ID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP View Gene Set 5.333e-09 681 1.483e-07 86 Genes up-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN View Gene Set 5.398e-09 308 1.484e-07 87 Genes down-regulated in non-metastatic breast cancer tumors having type 1 amplification in the 20q13 region; involves ZNF217 [Gene ID=7764] locus only. www.broad.mit.e...
Broad WEST_ADRENOCORTICAL_TUMOR_UP View Gene Set 7.96e-09 283 2.164e-07 88 Up-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue. www.broad.mit.e...
Broad SONG_TARGETS_OF_IE86_CMV_PROTEIN View Gene Set 8.42e-09 49 2.263e-07 89 Cellular genes up-regulated in forskin fibroblasts by expression of CMV EI86 protein off an adenovirus vector. www.broad.mit.e...
Broad LY_AGING_MIDDLE_DN View Gene Set 1.353e-08 15 3.596e-07 90 Genes down-regulated in fibroblasts from middle-age individuals compared to those from the young donors. www.broad.mit.e...
Broad SCHUHMACHER_MYC_TARGETS_UP View Gene Set 1.586e-08 68 4.169e-07 91 Genes up-regulated in P493-6 cells (Burkitt's lymphoma) induced to express MYC [Gene ID=4609]. www.broad.mit.e...
Broad NAKAMURA_CANCER_MICROENVIRONMENT_DN View Gene Set 1.948e-08 45 5.065e-07 92 Genes down-regulated in pancreatic cancer cells grown in orthotopic xenograft tumors compared to those grown in vitro. www.broad.mit.e...
Broad YU_MYC_TARGETS_UP View Gene Set 2.592e-08 37 6.666e-07 93 Genes up-regulated in B cell lymphoma tumors expressing an activated form of MYC [Gene ID=4609]. www.broad.mit.e...
Broad RHODES_UNDIFFERENTIATED_CANCER View Gene Set 2.854e-08 60 7.262e-07 94 Genes commonly up-regulated in undifferentiated cancer relative to well-differentiated cancer based on the meta-analysis of the OncoMine gene expression database. www.broad.mit.e...
Broad MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP View Gene Set 4.241e-08 359 1.068e-06 95 The postradiation tumor escape signature: genes up-regulated in tumors from irradiated stroma vs those from non-irradiated stroma. www.broad.mit.e...
Broad WONG_PROTEASOME_GENE_MODULE View Gene Set 4.487e-08 46 1.118e-06 96 Genes that comprise the proteasome gene module www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN View Gene Set 4.778e-08 46 1.178e-06 97 Cluster 6: genes down-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] in combination with serum but not affected by serum alone; they are also up-regulated by MYC alone. www.broad.mit.e...
Broad BENPORATH_MYC_MAX_TARGETS View Gene Set 5.08e-08 768 1.24e-06 98 Set 'Myc targets2': targets of c-Myc [Gene ID=4609] and Max [Gene ID=4149] identified by ChIP on chip in a Burkitt???s lymphoma cell line; overlap set. www.broad.mit.e...
Broad LEE_EARLY_T_LYMPHOCYTE_UP View Gene Set 6.562e-08 80 1.586e-06 99 Genes up-regulated at early stages of progenitor T lymphocyte maturation compared to the late stages. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP View Gene Set 8.071e-08 45 1.931e-06 100 Cluster 5: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] alone or in combination with serum but not by serum alone. www.broad.mit.e...
Broad PUJANA_BREAST_CANCER_LIT_INT_NETWORK View Gene Set 8.352e-08 100 1.978e-06 101 Genes constituting the LIT-Int network of proteins interacting with breast cancer reference proteins BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200]; the interactions were manually curated from the literature. www.broad.mit.e...
Broad WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 View Gene Set 1.253e-07 36 2.937e-06 102 Genes downstream of both CDKN1A and TP53 [Gene ID=1026 7157] in 2774qw1 cells (ovarian cancer). www.broad.mit.e...
Broad DANG_REGULATED_BY_MYC_UP View Gene Set 1.729e-07 65 4.014e-06 103 Genes up-regulated by MYC [Gene ID=4609] according to the MYC Target Gene Database. www.broad.mit.e...
Broad NADERI_BREAST_CANCER_PROGNOSIS_UP View Gene Set 2.61e-07 37 6.003e-06 104 Up-regulated genes in the breast cancer prognostic signature of 70 genes that significantly correlated with survival. www.broad.mit.e...
Broad BHATTACHARYA_EMBRYONIC_STEM_CELL View Gene Set 3.303e-07 76 7.526e-06 105 The 'stemnes' signature: genes up-regulated and common to 6 human embryonic stem cell lines tested. www.broad.mit.e...
Broad ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN View Gene Set 3.354e-07 61 7.568e-06 106 Genes down-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]. www.broad.mit.e...
Broad FINETTI_BREAST_CANCER_KINOME_RED View Gene Set 3.422e-07 15 7.578e-06 107 Genes in the red cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. www.broad.mit.e...
Broad FINETTI_BREAST_CANCER_BASAL_VS_LUMINAL View Gene Set 3.422e-07 15 7.578e-06 107 Protein kinases distinguishing between basal and luminal A subtypes of breast cancer. www.broad.mit.e...
Broad CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP View Gene Set 3.863e-07 47 8.477e-06 109 Genes up-regulated by 2-methoxyestradiol (2ME2) [PubChem=1573] in the MM.1S cell line (multiple myeloma) sensitive to dexamethasone [PubChem=5743]. www.broad.mit.e...
Broad SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN View Gene Set 4.423e-07 22 9.617e-06 110 Cell cycle genes changed in H1299 cells (lung cancer) after overexpression of either P53 [Gene ID=7157] or P73 [Gene ID=7161]. www.broad.mit.e...
Broad MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN View Gene Set 4.85e-07 212 1.045e-05 111 Genes down-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199]. www.broad.mit.e...
Broad LEE_LIVER_CANCER_SURVIVAL_DN View Gene Set 1.121e-06 123 2.394e-05 112 Genes highly expressed in hepatocellular carcinoma with poor survival. www.broad.mit.e...
Broad RAMALHO_STEMNESS_UP View Gene Set 2.103e-06 192 4.451e-05 113 Genes enriched in embryonic neural and hematopoietic stem cells. www.broad.mit.e...
Broad LE_EGR2_TARGETS_UP View Gene Set 2.787e-06 100 5.848e-05 114 Genes up-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [Gene ID=1959]. www.broad.mit.e...
Broad TANG_SENESCENCE_TP53_TARGETS_DN View Gene Set 2.894e-06 40 6.02e-05 115 Genes down-regulated in WI-38 cells (senescent primary fibroblasts) after inactivation of TP53 [Gene ID=7157] by GSE56 polypeptide. www.broad.mit.e...
Broad SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP View Gene Set 3.125e-06 269 6.444e-05 116 Genes up-regulated in nsopharyngeal carcinoma relative to the normal tissue. www.broad.mit.e...
Broad ZHANG_RESPONSE_TO_CANTHARIDIN_DN View Gene Set 3.381e-06 60 6.912e-05 117 Genes down-regulated in HL-60 cells (promyeloid leukemia) by cantharidin [PubChem=6708701]. www.broad.mit.e...
Broad HESS_TARGETS_OF_HOXA9_AND_MEIS1_UP View Gene Set 3.441e-06 59 6.976e-05 118 Genes up-regulated in hematopoietic precursor cells conditionally expressing HOXA9 and MEIS1 [Gene ID=3205 4211]. www.broad.mit.e...
Broad CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP View Gene Set 4.784e-06 51 9.617e-05 119 Protein biosynthesis transport or catabolism genes up-regulated in hyperploid multiple myeloma (MM) compared to the non-hyperploid MM samples. www.broad.mit.e...
Broad RIZ_ERYTHROID_DIFFERENTIATION_CCNE1 View Gene Set 4.844e-06 38 9.656e-05 120 Selected gradually up-regulated genes whose expression profile follows that of CCNE1 [Gene ID=898] in the TLX1 [Gene ID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). www.broad.mit.e...
Broad MENSSEN_MYC_TARGETS View Gene Set 4.983e-06 16 9.851e-05 121 Genes up-regulated by adenoviral expression of c-MYC [Gene ID=4609] in HUVEC cells (umbilical vein endothelium). www.broad.mit.e...
Broad POMEROY_MEDULLOBLASTOMA_PROGNOSIS_DN View Gene Set 5.221e-06 39 0.0001024 122 Top marker genes in medulloblastoma associated with poor response to treatment (poor outcome). www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_14HR_UP View Gene Set 5.296e-06 150 0.000103 123 Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not up-regulated at the previous time point 12 h. www.broad.mit.e...
Broad GEORGES_CELL_CYCLE_MIR192_TARGETS View Gene Set 5.594e-06 59 0.0001079 124 Experimentally validated direct targets of MIR192 [Gene ID=406967] microRNA; MIR192 caused cell cycle arrest in HCT116 cells (colon cancer). www.broad.mit.e...
Broad SMID_BREAST_CANCER_LUMINAL_A_DN View Gene Set 6.331e-06 17 0.0001212 125 Genes down-regulated in the luminal A subtype of breast cancer. www.broad.mit.e...
Broad DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP View Gene Set 6.865e-06 1353 0.0001303 126 Genes up-regulated in CD34+ [Gene ID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients compared to those from normal donors. www.broad.mit.e...
Broad MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP View Gene Set 7.45e-06 92 0.0001403 127 Genes correlated with the early tumor onset in the Emu-myc transgenic mouse lymphoma model. www.broad.mit.e...
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP View Gene Set 7.594e-06 469 0.0001419 128 Genes up-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. www.broad.mit.e...
Broad MATTIOLI_MGUS_VS_PCL View Gene Set 8.057e-06 109 0.0001494 129 Genes changed in MGUS (monoclonal gammopathy of undetermined significance) compared to PCL (plasma cell leukemia) samples. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 View Gene Set 8.838e-06 165 0.0001626 130 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 17. www.broad.mit.e...
Broad FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN View Gene Set 1.27e-05 76 0.0002319 131 Top 100 genes positively (UP) and negatively (DN) associated with T-cell acute lymphoblastic leukemia MLL T-ALL) expressing MLL-ENL fusion [Gene ID=4297 4298]. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN View Gene Set 1.288e-05 160 0.0002335 132 Genes down-regulated in metastatic breast cancer tumors having type 2 amplification in the 20q13 region; involves MYBL2 STK6 and ZNF217 [Gene ID=4605 6790 7764] www.broad.mit.e...
Broad PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP View Gene Set 1.518e-05 175 0.0002731 133 Up-regulated genes in head and neck cancer compared to cervical carcinoma samples. www.broad.mit.e...
Broad MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN View Gene Set 1.714e-05 42 0.0003059 134 Genes down-regulated in normal bone marrow plasma cells (BMPC) compared to polyclonal plasmablasts (PPC) that also distinguished multiple myeloma (MM) samples by expression of levels of TACI [Gene ID=23495]. www.broad.mit.e...
Broad MOOTHA_HUMAN_MITODB_6_2002 View Gene Set 2.163e-05 420 0.0003833 135 Mitochondrial genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 View Gene Set 2.211e-05 93 0.0003888 136 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 11. www.broad.mit.e...
Broad MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP View Gene Set 2.246e-05 10 0.0003921 137 Up-regulated genes predicting poor survival of patients with thyroid carcinoma. www.broad.mit.e...
Broad KUMAMOTO_RESPONSE_TO_NUTLIN_3A_DN View Gene Set 2.301e-05 10 0.0003989 138 Genes down-regulated in response to nutlin-3a [PubChem=216345] an inhibitor of MDM2 [Gene ID=4193] in skin fibroblast cultures after knockdown of TP53 [Gene ID=7157] by RNAi. www.broad.mit.e...
Broad SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY View Gene Set 2.444e-05 31 0.0004206 139 Cluster 3: genes strongly up-regulated in B493-6 cells (B lymphocytes) by a combination of MYC [Gene ID=4609] and serum but not by each of them alone. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP View Gene Set 3.089e-05 52 0.0005278 140 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G23 defined by unsupervised clustering. www.broad.mit.e...
Broad MOOTHA_MITOCHONDRIA View Gene Set 4.031e-05 433 0.0006838 141 Mitochondrial genes www.broad.mit.e...
Broad CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP View Gene Set 4.531e-05 135 0.0007633 142 Top 200 marker genes up-regulated in the 'proliferation' subclass of hepatocellular carcinoma (HCC); characterized by increased proliferation high levels of serum AFP [Gene ID=174] and chromosomal instability. www.broad.mit.e...
Broad LEE_METASTASIS_AND_RNA_PROCESSING_UP View Gene Set 4.814e-05 15 0.0008053 143 Components of RNA post-transcriptional modification machinery up-regulated in MDA-MB-435 cells (breast cancer) whose metastatic potential has been reduced by expression of NME1 [Gene ID=4830]. www.broad.mit.e...
Broad DAIRKEE_TERT_TARGETS_UP View Gene Set 4.963e-05 317 0.0008244 144 Genes up-regulated in non-spontaneously immortalizing (NSI) primary breast cancer tumor cultures upon expression of TERT [Gene ID=7015] off a retroviral vector. www.broad.mit.e...
Broad SEMBA_FHIT_TARGETS_DN View Gene Set 6.206e-05 10 0.001024 145 Genes down-regulated in H1299 cells (non-small cell lung cancer NSCLC) expressing the Y144F mutant form of FHIT [Gene ID=2272]. www.broad.mit.e...
Broad MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN View Gene Set 6.928e-05 121 0.001135 146 Genes distinguishing in multiple myeloma (MM) samples with lower expression of TACI [Gene ID=23495]. www.broad.mit.e...
Broad ELVIDGE_HYPOXIA_DN View Gene Set 8.59e-05 136 0.001398 147 Genes down-regulated in MCF7 cells (breast cancer) under hypoxia conditions. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP View Gene Set 9.502e-05 44 0.001528 148 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G123 defined by unsupervised clustering. www.broad.mit.e...
Broad RAMASWAMY_METASTASIS_UP View Gene Set 9.517e-05 63 0.001528 148 Up-regulated genes in metastatic vs primary solid tumors. www.broad.mit.e...
Broad SU_TESTIS View Gene Set 0.0001007 75 0.001605 150 Genes up-regulated specifically in human testis tissue. www.broad.mit.e...
Broad ZHAN_MULTIPLE_MYELOMA_SUBGROUPS View Gene Set 0.000102 28 0.001616 151 Top genes up-regulated in MM4 vs MM1 subgroup of multiple myeloma samples. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP View Gene Set 0.000155 36 0.002424 152 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_DN View Gene Set 0.000155 36 0.002424 152 Down-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors. www.broad.mit.e...
Broad PENG_RAPAMYCIN_RESPONSE_DN View Gene Set 0.0001823 69 0.002831 154 Genes down-regulated in BJUB cells (B-lymphoma) in response to rapamycin [PubChem=6610346] treatment. www.broad.mit.e...
Broad RHODES_CANCER_META_SIGNATURE View Gene Set 0.0002339 54 0.003609 155 Genes commonly up-regulated in cancer relative to normal tissue according to the meta-analysis of the OncoMine gene expression database. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 View Gene Set 0.0002534 131 0.003886 156 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 14. www.broad.mit.e...
Broad PENG_LEUCINE_DEPRIVATION_DN View Gene Set 0.0002665 50 0.004061 157 Genes down-regulated in BJAB cells (B-lymphoma) after leucine [PubChem=857] deprivation. www.broad.mit.e...
Broad IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR View Gene Set 0.0003397 100 0.005143 158 Genes in the expression cluster 'Early Progenitors Shared': up-regulated in hematopoietic progenitors from adult bone marrow and from fetal liver. www.broad.mit.e...
Broad CHIARETTI_T_ALL_RELAPSE_PROGNOSIS View Gene Set 0.0003427 12 0.005155 159 Genes whose expression predicted relapse in less than 2 years after chemotherapy for adult patients with T-ALL (T cell lymphoblastic leukemia). www.broad.mit.e...
Broad JISON_SICKLE_CELL_DISEASE_DN View Gene Set 0.0003561 168 0.005324 160 Genes down-regulated in peripheral blood mononuclear cells (PBMC) from sickle cell disease patients compared to those from healthy subjects. www.broad.mit.e...
Broad BASSO_B_LYMPHOCYTE_NETWORK View Gene Set 0.0004401 136 0.006539 161 Genes which comprise the top 1% of highly interconnected genes (major hubs) that account for most of gene interactions in the reconstructed regulatory networks from expression profiles in B lymphocytes. www.broad.mit.e...
Broad CHANG_CORE_SERUM_RESPONSE_UP View Gene Set 0.0005099 66 0.007529 162 Up-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group. www.broad.mit.e...
Broad SHEPARD_CRUSH_AND_BURN_MUTANT_DN View Gene Set 0.0005834 147 0.008561 163 Human orthologs of genes down-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [Gene ID=4605]. www.broad.mit.e...
Broad MEINHOLD_OVARIAN_CANCER_LOW_GRADE_DN View Gene Set 0.0006656 18 0.009708 164 Genes down-regulated in low grade (LMP and G1) serous ovarian carcinomas vs the higher grade invasive tumors (G2 and G3). www.broad.mit.e...
Broad WAKASUGI_HAVE_ZNF143_BINDING_SITES View Gene Set 0.0007141 55 0.01035 165 DNA repair genes whose promoters contain putative ZNF143 [Gene ID=7702] binding sites. www.broad.mit.e...
Broad LY_AGING_PREMATURE_DN View Gene Set 0.0007933 24 0.01143 166 Genes down-regulated in fibroblasts from patients with Hutchinson-Gilford progeria (premature aging) compared to those from normal young individuals. www.broad.mit.e...
Broad MILI_PSEUDOPODIA_HAPTOTAXIS_UP View Gene Set 0.0008131 452 0.01165 167 Transcripts enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin FN1 [Gene ID=2335]. www.broad.mit.e...
Broad LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP View Gene Set 0.0008296 168 0.01181 168 Genes with copy number gains in primary neuroblastoma tumors. www.broad.mit.e...
Broad ELVIDGE_HIF1A_TARGETS_UP View Gene Set 0.00085 64 0.01203 169 Genes up-regulated in MCF7 cells (breast cancer) after knockdown of HIF1A [Gene ID=3091] by RNAi. www.broad.mit.e...
Broad XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_DN View Gene Set 0.0008595 14 0.01209 170 Genes down-regulated synergistically in NB4 cells (acute promyelocytic leukemia APL) by tretinoin and NSC682994 [PubChem=5538 388304]. www.broad.mit.e...
Broad HOSHIDA_LIVER_CANCER_SUBCLASS_S2 View Gene Set 0.0008739 114 0.01222 171 Genes from 'subtype S2' signature of hepatocellular carcinoma (HCC): proliferation MYC and AKT1 [Gene ID=4609 207] activation. www.broad.mit.e...
Broad BENPORATH_ES_2 View Gene Set 0.0009234 39 0.01284 172 Set 'Set 'ES exp2': genes overexpressed in human embryonic stem cells according to a meta-analysis of 8 profiling studies. www.broad.mit.e...
Broad BORCZUK_MALIGNANT_MESOTHELIOMA_UP View Gene Set 0.001001 290 0.01384 173 Genes up-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma. www.broad.mit.e...
Broad GALE_APL_WITH_FLT3_MUTATED_UP View Gene Set 0.001015 52 0.01396 174 Genes up-regulated in acute promyelocytic leukemia (APL) patients with mutated FLT3 [Gene ID=2322]. www.broad.mit.e...
Broad PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN View Gene Set 0.001071 49 0.01464 175 Antigen processing and presentation genes down-regulated in JY cells (B lymphocytes) treated with trichostatin A (TSA) [PubChem=5562]. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP View Gene Set 0.001079 220 0.01467 176 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors. www.broad.mit.e...
Broad CAFFAREL_RESPONSE_TO_THC_DN View Gene Set 0.001414 25 0.01911 177 Genes down-regulated in EVSA-T cells (breast cancer) treated THC (delta-9-tetrahydrocannabinol) [PubChem=6610319]. www.broad.mit.e...
Broad SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP View Gene Set 0.001523 16 0.02047 178 Genes up-regulated in MCF10A cells (breast cancer) grown at low (mesenchymal phenotype) compared to those grown at high (epithelial basal-like phenotype) confluency. www.broad.mit.e...
Broad DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2 View Gene Set 0.001592 111 0.02127 179 'Cancer prone response profile' (CPRP): genes common to estradiol and bisphenol A [PubChem=5757 6623] response of epithelial cell cultures from patients at high risk of breast cancer. www.broad.mit.e...
Broad WONG_MITOCHONDRIA_GENE_MODULE View Gene Set 0.001814 208 0.0241 180 Genes that comprise the mitochondria gene module www.broad.mit.e...
Broad MODY_HIPPOCAMPUS_PRENATAL View Gene Set 0.001846 27 0.02439 181 Genes highly expressed in prenatal hippocampus (cluster 1). www.broad.mit.e...
Broad VANTVEER_BREAST_CANCER_METASTASIS_DN View Gene Set 0.00189 104 0.02485 182 Genes whose expression is significantly and negatively correlated with poor breast cancer clinical outcome (defined as developing distant metastases in less than 5 years). www.broad.mit.e...
Broad STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN View Gene Set 0.002208 41 0.02886 183 Genes down-regulated by estradiol [PubChem=5757] and down-regulated by ESRRA [Gene ID=2101] in MCF-7 cells (breast cancer). www.broad.mit.e...
Broad PYEON_HPV_POSITIVE_TUMORS_UP View Gene Set 0.002251 86 0.02926 184 Up-regulated genes in cervical carcinoma and head and neck tumors positive for human papilloma virus (HPV) compared to those negative for HPV. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_6HR_UP View Gene Set 0.002408 50 0.03114 185 Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 6h. www.broad.mit.e...
Broad KOINUMA_COLON_CANCER_MSI_DN View Gene Set 0.002565 13 0.03298 186 Genes down-regulated in colorectal carcinoma samples positive for MSI (microsatellite instability) compared to the MSI negative ones. www.broad.mit.e...
Broad CAMPS_COLON_CANCER_COPY_NUMBER_UP View Gene Set 0.002611 75 0.0334 187 Genes from chromosomal copy number gains in a panel of 51 primary colon carcinoma samples. www.broad.mit.e...
Broad KALMA_E2F1_TARGETS View Gene Set 0.002643 11 0.03361 188 DNA replication genes up-regulated in a Rat-1a cell line (fibroblast) by expression of E2F1 [Gene ID=1869]. www.broad.mit.e...
Broad NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP View Gene Set 0.002655 87 0.03361 188 Top 100 probe sets contrubuting to the positive side of the 2nd principal component; associated with adipocytic differentiation. www.broad.mit.e...
Broad HSIAO_HOUSEKEEPING_GENES View Gene Set 0.002788 384 0.0351 190 Housekeeping genes identified as expressed across 19 normal tissues. www.broad.mit.e...
Broad COLLER_MYC_TARGETS_UP View Gene Set 0.002841 12 0.03558 191 Genes regulated by forced expression of MYC [Gene ID=4609] in 293T (transformed fetal renal cell). www.broad.mit.e...
Broad DAZARD_UV_RESPONSE_CLUSTER_G6 View Gene Set 0.003003 122 0.03741 192 Cluster G6: genes increasingly down-regulated in NHEK cells (normal keratinocyte) after UV-B irradiation. www.broad.mit.e...
Broad GOLDRATH_ANTIGEN_RESPONSE View Gene Set 0.003185 315 0.03932 193 Genes up-regulated at the peak of an antigen response of naive CD8+ [Gene ID=925 926] T-cells. www.broad.mit.e...
Broad KIM_GASTRIC_CANCER_CHEMOSENSITIVITY View Gene Set 0.003189 97 0.03932 193 Genes up-regulated in gastric cancer patients refractory to chemotherapy treatment with 5-fluorouracil and cisplatin [PubChem=3385 2767] compared to the sensitive state. www.broad.mit.e...
Broad JAIN_NFKB_SIGNALING View Gene Set 0.003466 73 0.04252 195 Genes abnormally regulated in response to CD40L and IL4 [Gene ID=959 3565] stimulation of B lymphocytes from patients with a hypomorphic mutation of IKBKG [Gene ID=8517]. www.broad.mit.e...
Broad JAZAG_TGFB1_SIGNALING_DN View Gene Set 0.003645 35 0.04448 196 Genes down-regulated in PANC-1-puro cells (pancreatic cancer) stimulated by TGF1B [Gene ID=7040] for 2 h. www.broad.mit.e...
Broad GOLDRATH_HOMEOSTATIC_PROLIFERATION View Gene Set 0.003722 154 0.04519 197 Up-regulated in CD8+ [Gene ID=925] T lymphocytes undergoing homeostatic proliferation (HP) versus the naive cells; these genes are not up-regulated versus effector or memory cell population. www.broad.mit.e...
Broad FUNG_IL2_SIGNALING_1 View Gene Set 0.003856 10 0.04658 198 Genes up-regulated by IL2 [Gene ID=3558] in both primary thymocytes and T1 cells (primary thymocytes immortalized by Tax an HTLV-1 encoded gene). www.broad.mit.e...
Broad SHEPARD_BMYB_TARGETS View Gene Set 0.00395 60 0.04748 199 Human orthologs of BMYB [Gene ID=4605] target genes in zebra fish identified as commonly changed in the BMYB loss of function mutant crb ('crush and burn') and after knockdown of BMYB by morpholino. www.broad.mit.e...
Broad CHOW_RASSF1_TARGETS_UP View Gene Set 0.003989 27 0.0477 200 Genes up-regulated in C666-1 cells (nasopharyngeal carcinoma) by stable expression of RASSF1 [Gene ID=11186]. www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.BIOCARTA

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad BIOCARTA_RANMS_PATHWAY View Gene Set 4.179e-06 10 0.0009069 1 Role of Ran in mitotic spindle regulation www.broad.mit.e...
Broad BIOCARTA_PROTEASOME_PATHWAY View Gene Set 9.244e-05 19 0.01003 2 Proteasome Complex www.broad.mit.e...
Broad BIOCARTA_ATRBRCA_PATHWAY View Gene Set 0.0003605 21 0.02607 3 Role of BRCA1 BRCA2 and ATR in Cancer Susceptibility www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.KEGG

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad KEGG_SPLICEOSOME View Gene Set 6.274e-23 118 1.167e-20 1 Spliceosome www.broad.mit.e...
Broad KEGG_CELL_CYCLE View Gene Set 1.12e-10 128 1.041e-08 2 Cell cycle www.broad.mit.e...
Broad KEGG_PROTEASOME View Gene Set 1.867e-10 48 1.158e-08 3 Proteasome www.broad.mit.e...
Broad KEGG_RIBOSOME View Gene Set 2.59e-08 88 1.204e-06 4 Ribosome www.broad.mit.e...
Broad KEGG_PYRIMIDINE_METABOLISM View Gene Set 5.924e-08 98 2.204e-06 5 Pyrimidine metabolism www.broad.mit.e...
Broad KEGG_DNA_REPLICATION View Gene Set 6.501e-07 36 2.015e-05 6 DNA replication www.broad.mit.e...
Broad KEGG_AMINOACYL_TRNA_BIOSYNTHESIS View Gene Set 3.797e-06 41 0.0001009 7 Aminoacyl-tRNA biosynthesis www.broad.mit.e...
Broad KEGG_RNA_DEGRADATION View Gene Set 6.78e-06 59 0.0001576 8 RNA degradation www.broad.mit.e...
Broad KEGG_HOMOLOGOUS_RECOMBINATION View Gene Set 4.322e-05 28 0.0008932 9 Homologous recombination www.broad.mit.e...
Broad KEGG_RNA_POLYMERASE View Gene Set 0.0004432 29 0.008243 10 RNA polymerase www.broad.mit.e...
Broad KEGG_OLFACTORY_TRANSDUCTION View Gene Set 0.0009458 389 0.01599 11 Olfactory transduction www.broad.mit.e...
Broad KEGG_BASE_EXCISION_REPAIR View Gene Set 0.001117 35 0.01732 12 Base excision repair www.broad.mit.e...
Broad KEGG_ONE_CARBON_POOL_BY_FOLATE View Gene Set 0.001608 17 0.02301 13 One carbon pool by folate www.broad.mit.e...
Broad KEGG_MISMATCH_REPAIR View Gene Set 0.002359 23 0.03134 14 Mismatch repair www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.REACTOME

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad REACTOME_GENE_EXPRESSION View Gene Set 1.416e-37 415 6.088e-35 1 Genes involved in Gene Expression www.broad.mit.e...
Broad REACTOME_MITOTIC_M_M_G1_PHASES View Gene Set 5.896e-36 157 1.268e-33 2 Genes involved in Mitotic M-M/G1 phases www.broad.mit.e...
Broad REACTOME_CELL_CYCLE_MITOTIC View Gene Set 7.185e-35 306 1.03e-32 3 Genes involved in Cell Cycle Mitotic www.broad.mit.e...
Broad REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA View Gene Set 4.38e-26 128 4.709e-24 4 Genes involved in Processing of Capped Intron-Containing Pre-mRNA www.broad.mit.e...
Broad REACTOME_MITOTIC_PROMETAPHASE View Gene Set 1.365e-21 92 1.174e-19 5 Genes involved in Mitotic Prometaphase www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING View Gene Set 9.452e-21 97 6.774e-19 6 Genes involved in mRNA Splicing www.broad.mit.e...
Broad REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS View Gene Set 3.492e-19 124 2.145e-17 7 Genes involved in Elongation and Processing of Capped Transcripts www.broad.mit.e...
Broad REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT View Gene Set 3.19e-18 142 1.715e-16 8 Genes involved in Formation and Maturation of mRNA Transcript www.broad.mit.e...
Broad REACTOME_CELL_CYCLE_CHECKPOINTS View Gene Set 5.376e-17 110 2.569e-15 9 Genes involved in Cell Cycle Checkpoints www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_RNA View Gene Set 1.402e-16 95 6.028e-15 10 Genes involved in Metabolism of RNA www.broad.mit.e...
Broad REACTOME_DNA_REPLICATION_PRE_INITIATION View Gene Set 5.325e-16 76 2.081e-14 11 Genes involved in DNA Replication Pre-Initiation www.broad.mit.e...
Broad REACTOME_TRANSLATION View Gene Set 4.765e-15 120 1.708e-13 12 Genes involved in Translation www.broad.mit.e...
Broad REACTOME_G1_S_TRANSITION View Gene Set 6.085e-15 102 2.013e-13 13 Genes involved in G1/S Transition www.broad.mit.e...
Broad REACTOME_M_G1_TRANSITION View Gene Set 1.239e-14 61 3.804e-13 14 Genes involved in M/G1 Transition www.broad.mit.e...
Broad REACTOME_SYNTHESIS_OF_DNA View Gene Set 5.911e-14 89 1.695e-12 15 Genes involved in Synthesis of DNA www.broad.mit.e...
Broad REACTOME_S_PHASE View Gene Set 8.826e-13 103 2.372e-11 16 Genes involved in S Phase www.broad.mit.e...
Broad REACTOME_INFLUENZA_LIFE_CYCLE View Gene Set 1.56e-12 137 3.946e-11 17 Genes involved in Influenza Life Cycle www.broad.mit.e...
Broad REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT View Gene Set 4.077e-12 106 9.74e-11 18 Genes involved in GTP hydrolysis and joining of the 60S ribosomal subunit www.broad.mit.e...
Broad REACTOME_SNRNP_ASSEMBLY View Gene Set 4.661e-12 50 1.055e-10 19 Genes involved in snRNP Assembly www.broad.mit.e...
Broad REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX View Gene Set 1.029e-11 52 2.213e-10 20 Genes involved in CDT1 association with the CDC6:ORC:origin complex www.broad.mit.e...
Broad REACTOME_REGULATION_OF_APC_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE View Gene Set 1.711e-11 71 3.503e-10 21 Genes involved in Regulation of APC/C activators between G1/S and early anaphase www.broad.mit.e...
Broad REACTOME_ORC1_REMOVAL_FROM_CHROMATIN View Gene Set 2.638e-11 63 5.156e-10 22 Genes involved in Orc1 removal from chromatin www.broad.mit.e...
Broad REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 View Gene Set 7.28e-11 48 1.361e-09 23 Genes involved in SCF-beta-TrCP mediated degradation of Emi1 www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION View Gene Set 7.62e-11 188 1.365e-09 24 Genes involved in Transcription www.broad.mit.e...
Broad REACTOME_CDC20_PHOSPHO_APC_MEDIATED_DEGRADATION_OF_CYCLIN_A View Gene Set 1.749e-10 63 3.008e-09 25 Genes involved in Cdc20:Phospho-APC/C mediated degradation of Cyclin A www.broad.mit.e...
Broad REACTOME_G2_M_CHECKPOINTS View Gene Set 3.422e-10 43 5.659e-09 26 Genes involved in G2/M Checkpoints www.broad.mit.e...
Broad REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS View Gene Set 6.634e-10 120 1.056e-08 27 Genes involved in Host Interactions of HIV factors www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_PROTEINS View Gene Set 7.389e-10 215 1.135e-08 28 Genes involved in Metabolism of proteins www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRON_CONTAINING_TRANSCRIPT View Gene Set 8.031e-10 42 1.191e-08 29 Genes involved in Transport of Mature mRNA derived from an Intron-Containing Transcript www.broad.mit.e...
Broad REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS View Gene Set 8.375e-10 95 1.2e-08 30 Genes involved in Formation of a pool of free 40S subunits www.broad.mit.e...
Broad REACTOME_HIV_INFECTION View Gene Set 1.202e-09 183 1.667e-08 31 Genes involved in HIV Infection www.broad.mit.e...
Broad REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC View Gene Set 1.815e-09 57 2.439e-08 32 Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C www.broad.mit.e...
Broad REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE View Gene Set 2.271e-09 47 2.96e-08 33 Genes involved in Regulation of ornithine decarboxylase (ODC) www.broad.mit.e...
Broad REACTOME_SIGNALING_BY_WNT View Gene Set 2.429e-09 58 3.072e-08 34 Genes involved in Signaling by Wnt www.broad.mit.e...
Broad REACTOME_TELOMERE_MAINTENANCE View Gene Set 3.219e-09 77 3.955e-08 35 Genes involved in Telomere Maintenance www.broad.mit.e...
Broad REACTOME_STABILIZATION_OF_P53 View Gene Set 3.357e-09 46 4.01e-08 36 Genes involved in Stabilization of p53 www.broad.mit.e...
Broad REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE View Gene Set 4.163e-09 43 4.838e-08 37 Genes involved in p53-Independent DNA Damage Response www.broad.mit.e...
Broad REACTOME_PEPTIDE_CHAIN_ELONGATION View Gene Set 6.576e-09 84 7.442e-08 38 Genes involved in Peptide chain elongation www.broad.mit.e...
Broad REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G View Gene Set 7.365e-09 47 8.12e-08 39 Genes involved in Vif-mediated degradation of APOBEC3G www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS View Gene Set 2.727e-08 37 2.932e-07 40 Genes involved in Activation of ATR in response to replication stress www.broad.mit.e...
Broad REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION View Gene Set 5.744e-08 100 6.024e-07 41 Genes involved in Influenza Viral RNA Transcription and Replication www.broad.mit.e...
Broad REACTOME_TRNA_AMINOACYLATION View Gene Set 6.559e-08 40 6.715e-07 42 Genes involved in tRNA Aminoacylation www.broad.mit.e...
Broad REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21 View Gene Set 1.008e-07 52 1.008e-06 43 Genes involved in SCF(Skp2)-mediated degradation of p2721 www.broad.mit.e...
Broad REACTOME_REV_MEDIATED_NUCLEAR_EXPORT_OF_HIV1_RNA View Gene Set 1.155e-07 31 1.129e-06 44 Genes involved in Rev-mediated nuclear export of HIV-1 RNA www.broad.mit.e...
Broad REACTOME_VIRAL_MRNA_TRANSLATION View Gene Set 1.513e-07 84 1.445e-06 45 Genes involved in Viral mRNA Translation www.broad.mit.e...
Broad REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN View Gene Set 1.556e-07 30 1.455e-06 46 Genes involved in Nuclear import of Rev protein www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_THE_SLBP_INDEPENDENT_MATURE_MRNA View Gene Set 2.966e-07 32 2.714e-06 47 Genes involved in Transport of the SLBP independent Mature mRNA www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX View Gene Set 4.203e-07 30 3.766e-06 48 Genes involved in Activation of the pre-replicative complex www.broad.mit.e...
Broad REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY View Gene Set 4.695e-07 29 4.12e-06 49 Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery www.broad.mit.e...
Broad REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT View Gene Set 5.321e-07 114 4.486e-06 50 Genes involved in Regulation of beta-cell development www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS View Gene Set 5.292e-07 29 4.486e-06 50 Genes involved in Transport of Ribonucleoproteins into the Host Nucleus www.broad.mit.e...
Broad REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION View Gene Set 6.119e-07 23 5.06e-06 52 Genes involved in Cytosolic tRNA aminoacylation www.broad.mit.e...
Broad REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS View Gene Set 7.389e-07 101 5.995e-06 53 Genes involved in Regulation of gene expression in beta cells www.broad.mit.e...
Broad REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION View Gene Set 8.653e-07 56 6.89e-06 54 Genes involved in Translation initiation complex formation www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_MRNA View Gene Set 1.342e-06 45 1.049e-05 55 Genes involved in Metabolism of mRNA www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_III_AND_MITOCHONDRIAL_TRANSCRIPTION View Gene Set 2.164e-06 120 1.662e-05 56 Genes involved in RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING_MINOR_PATHWAY View Gene Set 2.321e-06 38 1.751e-05 57 Genes involved in mRNA Splicing - Minor Pathway www.broad.mit.e...
Broad REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE View Gene Set 4.05e-06 90 2.951e-05 58 Genes involved in Late Phase of HIV Life Cycle www.broad.mit.e...
Broad REACTOME_MRNA_3_END_PROCESSING View Gene Set 4.004e-06 25 2.951e-05 58 Genes involved in mRNA 3-end processing www.broad.mit.e...
Broad REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ View Gene Set 4.186e-06 58 3e-05 60 Genes involved in Cyclin E associated events during G1/S transition www.broad.mit.e...
Broad REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR View Gene Set 7.161e-06 15 5.048e-05 61 Genes involved in Homologous Recombination Repair www.broad.mit.e...
Broad REACTOME_VPR_MEDIATED_NUCLEAR_IMPORT_OF_PICS View Gene Set 7.487e-06 31 5.193e-05 62 Genes involved in Vpr-mediated nuclear import of PICs www.broad.mit.e...
Broad REACTOME_PACKAGING_OF_TELOMERE_ENDS View Gene Set 9.727e-06 49 6.639e-05 63 Genes involved in Packaging Of Telomere Ends www.broad.mit.e...
Broad REACTOME_DOUBLE_STRAND_BREAK_REPAIR View Gene Set 1.047e-05 21 7.034e-05 64 Genes involved in Double-Strand Break Repair www.broad.mit.e...
Broad REACTOME_DNA_STRAND_ELONGATION View Gene Set 1.221e-05 31 7.999e-05 65 Genes involved in DNA strand elongation www.broad.mit.e...
Broad REACTOME_HIV_LIFE_CYCLE View Gene Set 1.228e-05 103 7.999e-05 65 Genes involved in HIV Life Cycle www.broad.mit.e...
Broad REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN View Gene Set 2.338e-05 29 0.00015 67 Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein www.broad.mit.e...
Broad REACTOME_DNA_REPAIR View Gene Set 2.923e-05 102 0.0001822 68 Genes involved in DNA Repair www.broad.mit.e...
Broad REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION View Gene Set 2.903e-05 33 0.0001822 68 Genes involved in E2F mediated regulation of DNA replication www.broad.mit.e...
Broad REACTOME_EXTENSION_OF_TELOMERES View Gene Set 3.532e-05 28 0.000217 70 Genes involved in Extension of Telomeres www.broad.mit.e...
Broad REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX View Gene Set 4.131e-05 49 0.0002502 71 Genes involved in Formation of the ternary complex and subsequently the 43S complex www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION View Gene Set 4.244e-05 83 0.0002534 72 Genes involved in RNA Polymerase II Transcription www.broad.mit.e...
Broad REACTOME_GLUCOSE_TRANSPORT View Gene Set 5.269e-05 38 0.0003104 73 Genes involved in Glucose transport www.broad.mit.e...
Broad REACTOME_UNWINDING_OF_DNA View Gene Set 6.284e-05 11 0.0003651 74 Genes involved in Unwinding of DNA www.broad.mit.e...
Broad REACTOME_METABLISM_OF_NUCLEOTIDES View Gene Set 0.0001371 71 0.0007862 75 Genes involved in Metablism of nucleotides www.broad.mit.e...
Broad REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC:ORIGIN_COMPLEX View Gene Set 0.0002057 11 0.001164 76 Genes involved in CDC6 association with the ORC:origin complex www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_AMINO_ACIDS View Gene Set 0.0002361 162 0.001318 77 Genes involved in Metabolism of amino acids www.broad.mit.e...
Broad REACTOME_E2F_TRANSCRIPTIONAL_TARGETS_AT_G1_S View Gene Set 0.0002823 22 0.001536 78 Genes involved in E2F transcriptional targets at G1/S www.broad.mit.e...
Broad REACTOME_OLFACTORY_SIGNALING_PATHWAY View Gene Set 0.0002817 371 0.001536 78 Genes involved in Olfactory Signaling Pathway www.broad.mit.e...
Broad REACTOME_G2_M_TRANSITION View Gene Set 0.0005609 84 0.003015 80 Genes involved in G2/M Transition www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_PROMOTER_CLEARANCE View Gene Set 0.000714 82 0.003791 81 Genes involved in RNA PolymerasePromoter Clearance www.broad.mit.e...
Broad REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES View Gene Set 0.0007531 11 0.003918 82 Genes involved in Recruitment of NuMA to mitotic centrosomes www.broad.mit.e...
Broad REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS View Gene Set 0.0007563 11 0.003918 82 Genes involved in Purine ribonucleoside monophosphate biosynthesis www.broad.mit.e...
Broad REACTOME_DEADENYLATION_OF_MRNA View Gene Set 0.00107 21 0.005478 84 Genes involved in Deadenylation of mRNA www.broad.mit.e...
Broad REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS View Gene Set 0.00144 29 0.007283 85 Genes involved in Association of TriC/CCT with target proteins during biosynthesis www.broad.mit.e...
Broad REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING View Gene Set 0.001901 50 0.009503 86 Genes involved in Chaperonin-mediated protein folding www.broad.mit.e...
Broad REACTOME_MTORC1_MEDIATED_SIGNALLING View Gene Set 0.001929 11 0.009536 87 Genes involved in mTORC1-mediated signalling www.broad.mit.e...
Broad REACTOME_MICRORNA_BIOGENESIS View Gene Set 0.00202 18 0.00982 88 Genes involved in MicroRNA biogenesis www.broad.mit.e...
Broad REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PREREPLICATIVE_COMPLEX View Gene Set 0.002033 12 0.00982 88 Genes involved in Association of licensing factors with the pre-replicative complex www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_PROMOTER_OPENING View Gene Set 0.002254 59 0.01077 90 Genes involved in RNA Polymerase I Promoter Opening www.broad.mit.e...
Broad REACTOME_CENTROSOME_MATURATION View Gene Set 0.002439 72 0.0115 91 Genes involved in Centrosome maturation www.broad.mit.e...
Broad REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE View Gene Set 0.002461 11 0.0115 91 Genes involved in mRNA Decay by 3' to 5' Exoribonuclease www.broad.mit.e...
Broad REACTOME_APOPTOSIS View Gene Set 0.002488 129 0.01151 93 Genes involved in Apoptosis www.broad.mit.e...
Broad REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES View Gene Set 0.002557 18 0.0117 94 Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates www.broad.mit.e...
Broad REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC View Gene Set 0.002879 28 0.01303 95 Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_CARBOHYDRATES View Gene Set 0.003125 119 0.014 96 Genes involved in Metabolism of carbohydrates www.broad.mit.e...
Broad REACTOME_INACTIVATION_OF_APC_VIA_DIRECT_INHIBITION_OF_THE_APCOMPLEX View Gene Set 0.003947 18 0.0175 97 Genes involved in Inactivation of APC/C via direct inhibition of the APC/C complex www.broad.mit.e...
Broad REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION View Gene Set 0.005464 10 0.02398 98 Genes involved in E2F-enabled inhibition of pre-replication complex formation www.broad.mit.e...
Broad REACTOME_INSULIN_SYNTHESIS_AND_SECRETION View Gene Set 0.005828 129 0.02531 99 Genes involved in Insulin Synthesis and Secretion www.broad.mit.e...
Broad REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC View Gene Set 0.00612 22 0.02632 100 Genes involved in Formation of tubulin folding intermediates by CCT/TriC www.broad.mit.e...
Broad REACTOME_NUCLEOTIDE_EXCISION_REPAIR View Gene Set 0.006569 49 0.02797 101 Genes involved in Nucleotide Excision Repair www.broad.mit.e...
Broad REACTOME_MTOR_SIGNALLING View Gene Set 0.006924 27 0.02919 102 Genes involved in mTOR signalling www.broad.mit.e...
Broad REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION View Gene Set 0.007131 20 0.02963 103 Genes involved in Mitochondrial tRNA aminoacylation www.broad.mit.e...
Broad REACTOME_PYRIMIDINE_METABOLISM View Gene Set 0.007165 22 0.02963 103 Genes involved in Pyrimidine metabolism www.broad.mit.e...
Broad REACTOME_LAGGING_STRAND_SYNTHESIS View Gene Set 0.009228 20 0.03779 105 Genes involved in Lagging Strand Synthesis www.broad.mit.e...
Broad REACTOME_CYCLIN_A1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION View Gene Set 0.009841 15 0.03955 106 Genes involved in Cyclin A1 associated events during G2/M transition www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_RAC View Gene Set 0.009813 14 0.03955 106 Genes involved in Activation of Rac www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION View Gene Set 0.0124 34 0.04935 108 Genes involved in RNA Polymerase III Transcription www.broad.mit.e...

Gene Set Collection: Broad.c3.TFT

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad GCCATNTTG_V$YY1_Q6 View Gene Set 1.459e-12 289 8.971e-10 1 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTG which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad V$E2F_Q4 View Gene Set 2.161e-11 166 6.644e-09 2 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F_Q6 View Gene Set 8.507e-11 165 1.744e-08 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F_Q4_01 View Gene Set 1.283e-10 171 1.973e-08 4 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCSCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1_Q4_01 View Gene Set 2.175e-10 167 2.23e-08 5 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1_Q6_01 View Gene Set 1.993e-10 177 2.23e-08 5 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTTCGCGCS which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F_Q3 View Gene Set 3.207e-10 162 2.818e-08 7 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTCGCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F_03 View Gene Set 1.579e-09 171 1.214e-07 8 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGCGMNR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F_Q6_01 View Gene Set 2.374e-09 167 1.622e-07 9 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKCGCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$MYCMAX_01 View Gene Set 6.247e-09 189 3.493e-07 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNACCACGTGGTNN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X www.broad.mit.e...
Broad CACGTG_V$MYC_Q2 View Gene Set 5.989e-09 734 3.493e-07 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CACGTG which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian) www.broad.mit.e...
Broad V$E2F_Q3_01 View Gene Set 7.392e-09 171 3.788e-07 12 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1_Q3 View Gene Set 1.849e-08 176 8.745e-07 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKTSSCGC which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F1_Q6 View Gene Set 9.691e-08 167 4.257e-06 14 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGS which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$YY1_Q6 View Gene Set 5.839e-07 166 2.394e-05 15 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTN which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad V$E2F1_Q4 View Gene Set 6.364e-07 178 2.424e-05 16 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTSGCGG which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F1DP1RB_01 View Gene Set 6.7e-07 168 2.424e-05 16 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) www.broad.mit.e...
Broad GCGSCMNTTT_UNKNOWN View Gene Set 1.183e-06 49 3.86e-05 18 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GCGSCMNTTT. Motif does not match any known transcription factor www.broad.mit.e...
Broad SGCGSSAAA_V$E2F1DP2_01 View Gene Set 1.192e-06 122 3.86e-05 18 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SGCGSSAAA which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) www.broad.mit.e...
Broad V$NFMUE1_Q6 View Gene Set 1.811e-06 175 5.568e-05 20 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CGGCCATCT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MAX_01 View Gene Set 1.938e-06 194 5.675e-05 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNANCACGTGNTNN which matches annotation for MAX: MYC associated factor X www.broad.mit.e...
Broad V$E2F1DP1_01 View Gene Set 3.834e-06 169 9.825e-05 22 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1DP2_01 View Gene Set 3.834e-06 169 9.825e-05 22 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) www.broad.mit.e...
Broad V$E2F4DP2_01 View Gene Set 3.834e-06 169 9.825e-05 22 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) www.broad.mit.e...
Broad V$E2F_02 View Gene Set 4.018e-06 169 9.883e-05 25 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad SCGGAAGY_V$ELK1_02 View Gene Set 4.643e-06 784 0.0001098 26 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SCGGAAGY which matches annotation for ELK1: ELK1 member of ETS oncogene family www.broad.mit.e...
Broad V$E2F4DP1_01 View Gene Set 1.053e-05 174 0.0002398 27 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad GGCNKCCATNK_UNKNOWN View Gene Set 2.279e-05 84 0.0005006 28 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGCNKCCATNK. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF_01 View Gene Set 4.813e-05 186 0.001021 29 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNRYCACGTGRYNN. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$ARNT_01 View Gene Set 6.219e-05 196 0.001275 30 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NDDNNCACGTGNNNNN which matches annotation for ARNT: aryl hydrocarbon receptor nuclear translocator www.broad.mit.e...
Broad TAANNYSGCG_UNKNOWN View Gene Set 8.498e-05 60 0.001686 31 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TAANNYSGCG. Motif does not match any known transcription factor www.broad.mit.e...
Broad KTGGYRSGAA_UNKNOWN View Gene Set 9.025e-05 53 0.001734 32 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KTGGYRSGAA. Motif does not match any known transcription factor www.broad.mit.e...
Broad KCCGNSWTTT_UNKNOWN View Gene Set 0.0001338 76 0.002493 33 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KCCGNSWTTT. Motif does not match any known transcription factor www.broad.mit.e...
Broad RCGCANGCGY_V$NRF1_Q6 View Gene Set 0.0001522 580 0.002753 34 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RCGCANGCGY which matches annotation for NRF1: nuclear respiratory factor 1 www.broad.mit.e...
Broad TCCCRNNRTGC_UNKNOWN View Gene Set 0.0001899 130 0.003336 35 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TCCCRNNRTGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF_C View Gene Set 0.0002897 211 0.004949 36 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NCACGTGN. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$NMYC_01 View Gene Set 0.0004125 201 0.006857 37 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNCCACGTGNNN which matches annotation for MYCN: v-myc myelocytomatosis viral related oncogene neuroblastoma derived (avian) www.broad.mit.e...
Broad KRCTCNNNNMANAGC_UNKNOWN View Gene Set 0.0007131 60 0.01154 38 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KRCTCNNNNMANAGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$YY1_02 View Gene Set 0.0008701 168 0.01372 39 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNCGGCCATCTTGNCTSNW which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad ACAWNRNSRCGG_UNKNOWN View Gene Set 0.001038 50 0.01597 40 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ACAWNRNSRCGG. Motif does not match any known transcription factor www.broad.mit.e...
Broad GATGKMRGCG_UNKNOWN View Gene Set 0.001313 47 0.01969 41 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GATGKMRGCG. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MYCMAX_02 View Gene Set 0.001425 201 0.02086 42 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NANCACGTGNNW which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X www.broad.mit.e...
Broad V$GR_01 View Gene Set 0.001767 154 0.02527 43 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNNNGKACNNNNTGTTCTNNNNNN which matches annotation for NR3C1: nuclear receptor subfamily 3 group C member 1 (glucocorticoid receptor) www.broad.mit.e...
Broad V$E2F_01 View Gene Set 0.001994 55 0.02787 44 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TWSGCGCGAAAAYKR. Motif does not match any known transcription factor www.broad.mit.e...
Broad RRCCGTTA_UNKNOWN View Gene Set 0.00204 53 0.02787 45 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif RRCCGTTA. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$ARNT_02 View Gene Set 0.002375 179 0.03176 46 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNRTCACGTGAYNNNNN which matches annotation for ARNT: aryl hydrocarbon receptor nuclear translocator www.broad.mit.e...
Broad V$NFY_Q6_01 View Gene Set 0.003156 185 0.0413 47 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNNNRRCCAATSR. Motif does not match any known transcription factor www.broad.mit.e...
Broad CCAWNWWNNNGGC_UNKNOWN View Gene Set 0.003517 56 0.04507 48 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CCAWNWWNNNGGC. Motif does not match any known transcription factor www.broad.mit.e...

Gene Set Collection: Broad.c4.CGN

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad MORF_BUB3 View Gene Set 1.318e-31 256 5.629e-29 1 Neighborhood of BUB3 www.broad.mit.e...
Broad GNF2_RRM1 View Gene Set 2.134e-30 82 4.555e-28 2 Neighborhood of RRM1 www.broad.mit.e...
Broad MORF_UBE2I View Gene Set 1.087e-29 208 1.298e-27 3 Neighborhood of UBE2I www.broad.mit.e...
Broad GNF2_SMC4L1 View Gene Set 1.215e-29 75 1.298e-27 3 Neighborhood of SMC4L1 www.broad.mit.e...
Broad GNF2_RAN View Gene Set 7.317e-28 78 6.249e-26 5 Neighborhood of RAN www.broad.mit.e...
Broad MORF_EIF3S2 View Gene Set 1.483e-27 220 1.056e-25 6 Neighborhood of EIF3S2 www.broad.mit.e...
Broad GNF2_PCNA View Gene Set 6.486e-27 62 3.957e-25 7 Neighborhood of PCNA www.broad.mit.e...
Broad GNF2_CCNA2 View Gene Set 4.39e-26 62 2.343e-24 8 Neighborhood of CCNA2 www.broad.mit.e...
Broad GNF2_CCNB2 View Gene Set 4.173e-25 53 1.98e-23 9 Neighborhood of CCNB2 www.broad.mit.e...
Broad MORF_HDAC2 View Gene Set 1.07e-24 256 4.153e-23 10 Neighborhood of HDAC2 www.broad.mit.e...
Broad GNF2_PA2G4 View Gene Set 9.887e-25 73 4.153e-23 10 Neighborhood of PA2G4 www.broad.mit.e...
Broad MORF_PRKDC View Gene Set 1.274e-24 173 4.532e-23 12 Neighborhood of PRKDC www.broad.mit.e...
Broad GNF2_CDC20 View Gene Set 2.704e-24 52 8.881e-23 13 Neighborhood of CDC20 www.broad.mit.e...
Broad GNF2_CENPF View Gene Set 3.854e-24 56 1.175e-22 14 Neighborhood of CENPF www.broad.mit.e...
Broad GNF2_RFC4 View Gene Set 1.23e-23 57 3.502e-22 15 Neighborhood of RFC4 www.broad.mit.e...
Broad MORF_FBL View Gene Set 2.863e-23 121 7.64e-22 16 Neighborhood of FBL www.broad.mit.e...
Broad GNF2_CDC2 View Gene Set 8.305e-23 56 2.086e-21 17 Neighborhood of CDC2 www.broad.mit.e...
Broad MORF_AATF View Gene Set 1.145e-22 179 2.717e-21 18 Neighborhood of AATF www.broad.mit.e...
Broad MORF_RAD23A View Gene Set 2.219e-22 316 4.988e-21 19 Neighborhood of RAD23A www.broad.mit.e...
Broad MORF_RFC4 View Gene Set 9.613e-22 137 2.052e-20 20 Neighborhood of RFC4 www.broad.mit.e...
Broad GNF2_MCM4 View Gene Set 1.396e-21 50 2.838e-20 21 Neighborhood of MCM4 www.broad.mit.e...
Broad MORF_DEK View Gene Set 5.358e-21 229 1.04e-19 22 Neighborhood of DEK www.broad.mit.e...
Broad MORF_ANP32B View Gene Set 6.489e-21 174 1.205e-19 23 Neighborhood of ANP32B www.broad.mit.e...
Broad MORF_ACP1 View Gene Set 9.529e-21 178 1.695e-19 24 Neighborhood of ACP1 www.broad.mit.e...
Broad GNF2_NPM1 View Gene Set 1.422e-20 57 2.429e-19 25 Neighborhood of NPM1 www.broad.mit.e...
Broad GCM_APEX1 View Gene Set 3.182e-20 102 5.225e-19 26 Neighborhood of APEX1 www.broad.mit.e...
Broad MORF_PPP1CC View Gene Set 4.605e-20 150 7.283e-19 27 Neighborhood of PPP1CC www.broad.mit.e...
Broad MORF_DNMT1 View Gene Set 6.749e-20 105 1.029e-18 28 Neighborhood of DNMT1 www.broad.mit.e...
Broad GNF2_HMMR View Gene Set 1.982e-19 43 2.918e-18 29 Neighborhood of HMMR www.broad.mit.e...
Broad GNF2_FEN1 View Gene Set 8.094e-19 49 1.115e-17 30 Neighborhood of FEN1 www.broad.mit.e...
Broad GNF2_BUB1B View Gene Set 7.981e-19 46 1.115e-17 30 Neighborhood of BUB1B www.broad.mit.e...
Broad MORF_HAT1 View Gene Set 9.166e-19 155 1.223e-17 32 Neighborhood of HAT1 www.broad.mit.e...
Broad GNF2_FBL View Gene Set 1.332e-18 119 1.723e-17 33 Neighborhood of FBL www.broad.mit.e...
Broad GNF2_CKS1B View Gene Set 2.26e-18 36 2.838e-17 34 Neighborhood of CKS1B www.broad.mit.e...
Broad GNF2_ESPL1 View Gene Set 3.703e-18 35 4.518e-17 35 Neighborhood of ESPL1 www.broad.mit.e...
Broad GNF2_CKS2 View Gene Set 5.05e-18 45 5.99e-17 36 Neighborhood of CKS2 www.broad.mit.e...
Broad GNF2_CENPE View Gene Set 2.039e-17 37 2.353e-16 37 Neighborhood of CENPE www.broad.mit.e...
Broad MORF_RAN View Gene Set 2.34e-17 242 2.629e-16 38 Neighborhood of RAN www.broad.mit.e...
Broad GNF2_RRM2 View Gene Set 3.099e-17 36 3.308e-16 39 Neighborhood of RRM2 www.broad.mit.e...
Broad GNF2_MCM5 View Gene Set 3.07e-17 51 3.308e-16 39 Neighborhood of MCM5 www.broad.mit.e...
Broad MORF_SOD1 View Gene Set 3.45e-17 247 3.593e-16 41 Neighborhood of SOD1 www.broad.mit.e...
Broad GNF2_TTK View Gene Set 3.833e-17 34 3.897e-16 42 Neighborhood of TTK www.broad.mit.e...
Broad GNF2_RFC3 View Gene Set 4.439e-17 38 4.408e-16 43 Neighborhood of RFC3 www.broad.mit.e...
Broad GNF2_DEK View Gene Set 4.614e-17 45 4.478e-16 44 Neighborhood of DEK www.broad.mit.e...
Broad GCM_ACTG1 View Gene Set 2.507e-16 113 2.379e-15 45 Neighborhood of ACTG1 www.broad.mit.e...
Broad MORF_XRCC5 View Gene Set 2.891e-16 210 2.684e-15 46 Neighborhood of XRCC5 www.broad.mit.e...
Broad GNF2_APEX1 View Gene Set 4.086e-16 72 3.712e-15 47 Neighborhood of APEX1 www.broad.mit.e...
Broad MORF_RAD54L View Gene Set 6.96e-16 94 6.192e-15 48 Neighborhood of RAD54L www.broad.mit.e...
Broad MORF_NPM1 View Gene Set 8.265e-16 152 7.202e-15 49 Neighborhood of NPM1 www.broad.mit.e...
Broad MORF_CSNK2B View Gene Set 9.345e-16 256 7.981e-15 50 Neighborhood of CSNK2B www.broad.mit.e...
Broad MORF_G22P1 View Gene Set 9.858e-16 145 8.253e-15 51 Neighborhood of G22P1 www.broad.mit.e...
Broad GNF2_DAP3 View Gene Set 1.778e-15 98 1.46e-14 52 Neighborhood of DAP3 www.broad.mit.e...
Broad MORF_RRM1 View Gene Set 2.09e-15 90 1.684e-14 53 Neighborhood of RRM1 www.broad.mit.e...
Broad MORF_PCNA View Gene Set 3.773e-15 71 2.983e-14 54 Neighborhood of PCNA www.broad.mit.e...
Broad GNF2_SMC2L1 View Gene Set 1.861e-14 30 1.445e-13 55 Neighborhood of SMC2L1 www.broad.mit.e...
Broad MORF_ESPL1 View Gene Set 3.291e-14 58 2.51e-13 56 Neighborhood of ESPL1 www.broad.mit.e...
Broad GNF2_HAT1 View Gene Set 8.068e-14 45 6.044e-13 57 Neighborhood of HAT1 www.broad.mit.e...
Broad GNF2_MLH1 View Gene Set 8.245e-14 36 6.07e-13 58 Neighborhood of MLH1 www.broad.mit.e...
Broad GNF2_BUB1 View Gene Set 8.667e-14 25 6.272e-13 59 Neighborhood of BUB1 www.broad.mit.e...
Broad GNF2_EIF3S6 View Gene Set 1.594e-13 109 1.134e-12 60 Neighborhood of EIF3S6 www.broad.mit.e...
Broad MORF_BUB1B View Gene Set 1.623e-13 61 1.136e-12 61 Neighborhood of BUB1B www.broad.mit.e...
Broad GNF2_H2AFX View Gene Set 2.233e-13 28 1.538e-12 62 Neighborhood of H2AFX www.broad.mit.e...
Broad GNF2_MSH6 View Gene Set 3.984e-13 30 2.7e-12 63 Neighborhood of MSH6 www.broad.mit.e...
Broad MORF_UNG View Gene Set 4.245e-13 65 2.832e-12 64 Neighborhood of UNG www.broad.mit.e...
Broad MORF_FEN1 View Gene Set 4.649e-13 58 3.054e-12 65 Neighborhood of FEN1 www.broad.mit.e...
Broad GNF2_XRCC5 View Gene Set 6.082e-13 61 3.876e-12 66 Neighborhood of XRCC5 www.broad.mit.e...
Broad GNF2_ST13 View Gene Set 6.07e-13 56 3.876e-12 66 Neighborhood of ST13 www.broad.mit.e...
Broad GCM_NPM1 View Gene Set 6.571e-13 108 4.126e-12 68 Neighborhood of NPM1 www.broad.mit.e...
Broad GNF2_MKI67 View Gene Set 8.601e-13 26 5.322e-12 69 Neighborhood of MKI67 www.broad.mit.e...
Broad GCM_CSNK2B View Gene Set 9.496e-13 88 5.793e-12 70 Neighborhood of CSNK2B www.broad.mit.e...
Broad MORF_MSH2 View Gene Set 1.085e-12 52 6.524e-12 71 Neighborhood of MSH2 www.broad.mit.e...
Broad MORF_BUB1 View Gene Set 1.935e-12 49 1.147e-11 72 Neighborhood of BUB1 www.broad.mit.e...
Broad MORF_RAD21 View Gene Set 2.422e-12 157 1.416e-11 73 Neighborhood of RAD21 www.broad.mit.e...
Broad GNF2_NS View Gene Set 2.733e-12 35 1.577e-11 74 Neighborhood of NS www.broad.mit.e...
Broad GNF2_HDAC1 View Gene Set 2.825e-12 85 1.608e-11 75 Neighborhood of HDAC1 www.broad.mit.e...
Broad MORF_PPP2CA View Gene Set 4.254e-12 110 2.39e-11 76 Neighborhood of PPP2CA www.broad.mit.e...
Broad MORF_GNB1 View Gene Set 6.868e-12 276 3.809e-11 77 Neighborhood of GNB1 www.broad.mit.e...
Broad GNF2_KPNB1 View Gene Set 7.342e-12 52 4.019e-11 78 Neighborhood of KPNB1 www.broad.mit.e...
Broad GNF2_RBBP6 View Gene Set 8.468e-12 54 4.577e-11 79 Neighborhood of RBBP6 www.broad.mit.e...
Broad MORF_EIF4A2 View Gene Set 8.944e-12 120 4.774e-11 80 Neighborhood of EIF4A2 www.broad.mit.e...
Broad MORF_CDK2 View Gene Set 1.901e-11 63 1.002e-10 81 Neighborhood of CDK2 www.broad.mit.e...
Broad MORF_EI24 View Gene Set 2.249e-11 136 1.171e-10 82 Neighborhood of EI24 www.broad.mit.e...
Broad GCM_PSME1 View Gene Set 2.629e-11 76 1.353e-10 83 Neighborhood of PSME1 www.broad.mit.e...
Broad MORF_NME2 View Gene Set 6.927e-11 145 3.521e-10 84 Neighborhood of NME2 www.broad.mit.e...
Broad MORF_ACTG1 View Gene Set 1.623e-10 134 8.152e-10 85 Neighborhood of ACTG1 www.broad.mit.e...
Broad GCM_CBFB View Gene Set 1.715e-10 59 8.516e-10 86 Neighborhood of CBFB www.broad.mit.e...
Broad GNF2_G22P1 View Gene Set 3.382e-10 29 1.66e-09 87 Neighborhood of G22P1 www.broad.mit.e...
Broad MORF_ERH View Gene Set 4.064e-10 103 1.972e-09 88 Neighborhood of ERH www.broad.mit.e...
Broad MORF_SART1 View Gene Set 6.698e-10 55 3.213e-09 89 Neighborhood of SART1 www.broad.mit.e...
Broad MORF_HDAC1 View Gene Set 7.306e-10 222 3.466e-09 90 Neighborhood of HDAC1 www.broad.mit.e...
Broad MORF_CUL1 View Gene Set 8.559e-10 62 4.016e-09 91 Neighborhood of CUL1 www.broad.mit.e...
Broad MORF_RPA2 View Gene Set 1.206e-09 170 5.598e-09 92 Neighborhood of RPA2 www.broad.mit.e...
Broad MORF_EIF3S6 View Gene Set 1.474e-09 108 6.73e-09 93 Neighborhood of EIF3S6 www.broad.mit.e...
Broad GCM_PPP1CC View Gene Set 1.482e-09 47 6.73e-09 93 Neighborhood of PPP1CC www.broad.mit.e...
Broad MORF_DAP3 View Gene Set 1.592e-09 175 7.156e-09 95 Neighborhood of DAP3 www.broad.mit.e...
Broad MORF_CCNI View Gene Set 1.804e-09 76 7.94e-09 96 Neighborhood of CCNI www.broad.mit.e...
Broad GNF2_MSH2 View Gene Set 1.791e-09 26 7.94e-09 96 Neighborhood of MSH2 www.broad.mit.e...
Broad MORF_SMC1L1 View Gene Set 3.102e-09 47 1.352e-08 98 Neighborhood of SMC1L1 www.broad.mit.e...
Broad MORF_CDC16 View Gene Set 3.431e-09 67 1.48e-08 99 Neighborhood of CDC16 www.broad.mit.e...
Broad GNF2_DENR View Gene Set 4.028e-09 39 1.72e-08 100 Neighborhood of DENR www.broad.mit.e...
Broad GNF2_ANP32B View Gene Set 4.482e-09 29 1.895e-08 101 Neighborhood of ANP32B www.broad.mit.e...
Broad MORF_DDB1 View Gene Set 5.514e-09 220 2.308e-08 102 Neighborhood of DDB1 www.broad.mit.e...
Broad MORF_PTPN11 View Gene Set 6.172e-09 93 2.559e-08 103 Neighborhood of PTPN11 www.broad.mit.e...
Broad MORF_CDC10 View Gene Set 8.37e-09 120 3.436e-08 104 Neighborhood of CDC10 www.broad.mit.e...
Broad GNF2_TDG View Gene Set 1.06e-08 23 4.312e-08 105 Neighborhood of TDG www.broad.mit.e...
Broad MORF_TERF1 View Gene Set 1.778e-08 57 7.161e-08 106 Neighborhood of TERF1 www.broad.mit.e...
Broad MORF_PHB View Gene Set 2.605e-08 112 1.039e-07 107 Neighborhood of PHB www.broad.mit.e...
Broad MORF_RPA1 View Gene Set 3.035e-08 55 1.2e-07 108 Neighborhood of RPA1 www.broad.mit.e...
Broad MORF_PSMC1 View Gene Set 4.158e-08 162 1.629e-07 109 Neighborhood of PSMC1 www.broad.mit.e...
Broad MORF_PRKAG1 View Gene Set 4.343e-08 202 1.686e-07 110 Neighborhood of PRKAG1 www.broad.mit.e...
Broad GNF2_PPP6C View Gene Set 5.005e-08 33 1.925e-07 111 Neighborhood of PPP6C www.broad.mit.e...
Broad MORF_DEAF1 View Gene Set 6.81e-08 54 2.596e-07 112 Neighborhood of DEAF1 www.broad.mit.e...
Broad GCM_DDX5 View Gene Set 8.277e-08 52 3.128e-07 113 Neighborhood of DDX5 www.broad.mit.e...
Broad MORF_GSPT1 View Gene Set 1.382e-07 41 5.177e-07 114 Neighborhood of GSPT1 www.broad.mit.e...
Broad GNF2_ELAC2 View Gene Set 1.548e-07 32 5.747e-07 115 Neighborhood of ELAC2 www.broad.mit.e...
Broad GNF2_RPA1 View Gene Set 1.86e-07 20 6.846e-07 116 Neighborhood of RPA1 www.broad.mit.e...
Broad MORF_GMPS View Gene Set 2.066e-07 48 7.539e-07 117 Neighborhood of GMPS www.broad.mit.e...
Broad MORF_USP5 View Gene Set 2.161e-07 46 7.818e-07 118 Neighborhood of USP5 www.broad.mit.e...
Broad MORF_RAF1 View Gene Set 2.349e-07 94 8.43e-07 119 Neighborhood of RAF1 www.broad.mit.e...
Broad GCM_RAD21 View Gene Set 2.838e-07 30 1.01e-06 120 Neighborhood of RAD21 www.broad.mit.e...
Broad MORF_SKP1A View Gene Set 3.503e-07 175 1.236e-06 121 Neighborhood of SKP1A www.broad.mit.e...
Broad MORF_SNRP70 View Gene Set 3.799e-07 50 1.33e-06 122 Neighborhood of SNRP70 www.broad.mit.e...
Broad MORF_UBE2N View Gene Set 7.025e-07 79 2.439e-06 123 Neighborhood of UBE2N www.broad.mit.e...
Broad MORF_TPT1 View Gene Set 7.509e-07 100 2.586e-06 124 Neighborhood of TPT1 www.broad.mit.e...
Broad MORF_CCNF View Gene Set 7.989e-07 65 2.729e-06 125 Neighborhood of CCNF www.broad.mit.e...
Broad GNF2_BUB3 View Gene Set 1.027e-06 22 3.482e-06 126 Neighborhood of BUB3 www.broad.mit.e...
Broad MORF_CTBP1 View Gene Set 1.099e-06 149 3.695e-06 127 Neighborhood of CTBP1 www.broad.mit.e...
Broad GNF2_SMC1L1 View Gene Set 1.345e-06 24 4.488e-06 128 Neighborhood of SMC1L1 www.broad.mit.e...
Broad GCM_ANP32B View Gene Set 1.529e-06 32 5.06e-06 129 Neighborhood of ANP32B www.broad.mit.e...
Broad MORF_PPP1CA View Gene Set 1.935e-06 145 6.354e-06 130 Neighborhood of PPP1CA www.broad.mit.e...
Broad GCM_RAF1 View Gene Set 2.211e-06 34 7.205e-06 131 Neighborhood of RAF1 www.broad.mit.e...
Broad GCM_DFFA View Gene Set 7.04e-06 100 2.277e-05 132 Neighborhood of DFFA www.broad.mit.e...
Broad MORF_MAP2K2 View Gene Set 9.821e-06 123 3.153e-05 133 Neighborhood of MAP2K2 www.broad.mit.e...
Broad GNF2_UBE2I View Gene Set 1.547e-05 33 4.929e-05 134 Neighborhood of UBE2I www.broad.mit.e...
Broad MORF_RAD23B View Gene Set 1.674e-05 159 5.257e-05 135 Neighborhood of RAD23B www.broad.mit.e...
Broad GCM_TPT1 View Gene Set 1.674e-05 69 5.257e-05 135 Neighborhood of TPT1 www.broad.mit.e...
Broad MORF_JUND View Gene Set 3.72e-05 63 0.0001159 137 Neighborhood of JUND www.broad.mit.e...
Broad MORF_MTA1 View Gene Set 4.344e-05 95 0.0001344 138 Neighborhood of MTA1 www.broad.mit.e...
Broad MORF_EIF4E View Gene Set 4.623e-05 76 0.000142 139 Neighborhood of EIF4E www.broad.mit.e...
Broad GCM_MAX View Gene Set 9.618e-05 28 0.0002933 140 Neighborhood of MAX www.broad.mit.e...
Broad GCM_PFN1 View Gene Set 0.000142 47 0.0004302 141 Neighborhood of PFN1 www.broad.mit.e...
Broad MORF_TERF2IP View Gene Set 0.0002384 99 0.000717 142 Neighborhood of TERF2IP www.broad.mit.e...
Broad GNF2_TPT1 View Gene Set 0.0002435 38 0.0007272 143 Neighborhood of TPT1 www.broad.mit.e...
Broad MORF_AP3D1 View Gene Set 0.000354 119 0.001044 144 Neighborhood of AP3D1 www.broad.mit.e...
Broad GCM_TPR View Gene Set 0.0003544 29 0.001044 144 Neighborhood of TPR www.broad.mit.e...
Broad MORF_SS18 View Gene Set 0.0006421 55 0.001878 146 Neighborhood of SS18 www.broad.mit.e...
Broad GCM_MYST2 View Gene Set 0.0006933 138 0.002014 147 Neighborhood of MYST2 www.broad.mit.e...
Broad GCM_DENR View Gene Set 0.0009899 40 0.002856 148 Neighborhood of DENR www.broad.mit.e...
Broad MORF_BMI1 View Gene Set 0.001075 71 0.003079 149 Neighborhood of BMI1 www.broad.mit.e...
Broad MORF_REV3L View Gene Set 0.001249 52 0.003555 150 Neighborhood of REV3L www.broad.mit.e...
Broad GCM_UBE2N View Gene Set 0.001459 125 0.004125 151 Neighborhood of UBE2N www.broad.mit.e...
Broad MORF_AP2M1 View Gene Set 0.001534 197 0.004309 152 Neighborhood of AP2M1 www.broad.mit.e...
Broad MORF_WNT1 View Gene Set 0.001562 99 0.004358 153 Neighborhood of WNT1 www.broad.mit.e...
Broad GCM_HBP1 View Gene Set 0.002104 54 0.005832 154 Neighborhood of HBP1 www.broad.mit.e...
Broad GCM_PPM1D View Gene Set 0.002117 22 0.005832 154 Neighborhood of PPM1D www.broad.mit.e...
Broad MORF_SP3 View Gene Set 0.002648 69 0.007247 156 Neighborhood of SP3 www.broad.mit.e...
Broad GCM_HDAC1 View Gene Set 0.002999 30 0.008157 157 Neighborhood of HDAC1 www.broad.mit.e...
Broad GCM_MLL View Gene Set 0.003134 130 0.008471 158 Neighborhood of MLL www.broad.mit.e...
Broad GCM_SMARCC1 View Gene Set 0.003679 33 0.009879 159 Neighborhood of SMARCC1 www.broad.mit.e...
Broad GCM_CASP2 View Gene Set 0.003829 21 0.01022 160 Neighborhood of CASP2 www.broad.mit.e...
Broad GCM_AIP View Gene Set 0.005296 36 0.01404 161 Neighborhood of AIP www.broad.mit.e...
Broad MORF_FANCG View Gene Set 0.005456 148 0.01438 162 Neighborhood of FANCG www.broad.mit.e...
Broad MORF_BAG5 View Gene Set 0.006 48 0.01572 163 Neighborhood of BAG5 www.broad.mit.e...
Broad MORF_RFC1 View Gene Set 0.006039 98 0.01572 164 Neighborhood of RFC1 www.broad.mit.e...
Broad GCM_ZNF198 View Gene Set 0.008115 98 0.021 165 Neighborhood of ZNF198 www.broad.mit.e...
Broad MORF_MAP3K14 View Gene Set 0.008397 110 0.0216 166 Neighborhood of MAP3K14 www.broad.mit.e...
Broad MORF_PTEN View Gene Set 0.009769 80 0.02498 167 Neighborhood of PTEN www.broad.mit.e...
Broad MORF_PPP6C View Gene Set 0.009941 88 0.02527 168 Neighborhood of PPP6C www.broad.mit.e...
Broad MORF_PPP2R5E View Gene Set 0.01158 76 0.02925 169 Neighborhood of PPP2R5E www.broad.mit.e...
Broad MORF_RFC5 View Gene Set 0.01337 69 0.03349 170 Neighborhood of RFC5 www.broad.mit.e...
Broad GCM_GSPT1 View Gene Set 0.01341 129 0.03349 170 Neighborhood of GSPT1 www.broad.mit.e...
Broad GCM_CSNK1A1 View Gene Set 0.01352 28 0.03356 172 Neighborhood of CSNK1A1 www.broad.mit.e...
Broad MORF_RAP1A View Gene Set 0.01369 122 0.0338 173 Neighborhood of RAP1A www.broad.mit.e...
Broad MORF_BRCA1 View Gene Set 0.01434 242 0.0352 174 Neighborhood of BRCA1 www.broad.mit.e...
Broad MORF_TFDP2 View Gene Set 0.01533 215 0.03739 175 Neighborhood of TFDP2 www.broad.mit.e...
Broad MORF_IL13 View Gene Set 0.01785 216 0.0433 176 Neighborhood of IL13 www.broad.mit.e...
Broad GCM_CHUK View Gene Set 0.01805 61 0.04354 177 Neighborhood of CHUK www.broad.mit.e...
Broad GCM_TINF2 View Gene Set 0.01896 33 0.04549 178 Neighborhood of TINF2 www.broad.mit.e...
Broad GNF2_GLTSCR2 View Gene Set 0.02095 31 0.04998 179 Neighborhood of GLTSCR2 www.broad.mit.e...

Gene Set Collection: Broad.c4.CM

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad module_54 View Gene Set 7.073e-27 242 3.211e-24 1 Genes in module_54 www.broad.mit.e...
Broad module_198 View Gene Set 1.352e-22 288 3.07e-20 2 Genes in module_198 www.broad.mit.e...
Broad module_252 View Gene Set 1.333e-21 224 2.017e-19 3 Genes in module_252 www.broad.mit.e...
Broad module_98 View Gene Set 1.056e-20 375 1.198e-18 4 Genes in module_98 www.broad.mit.e...
Broad module_32 View Gene Set 1.408e-18 227 1.278e-16 5 Genes in module_32 www.broad.mit.e...
Broad module_17 View Gene Set 4.431e-17 351 3.353e-15 6 Genes in module_17 www.broad.mit.e...
Broad module_244 View Gene Set 9.404e-12 182 6.099e-10 7 Genes in module_244 www.broad.mit.e...
Broad module_183 View Gene Set 5.047e-11 52 2.864e-09 8 Genes in module_183 www.broad.mit.e...
Broad module_91 View Gene Set 7.37e-11 37 3.718e-09 9 Genes in module_91 www.broad.mit.e...
Broad module_158 View Gene Set 2.405e-10 41 1.092e-08 10 Genes in module_158 www.broad.mit.e...
Broad module_28 View Gene Set 3.327e-10 32 1.373e-08 11 Genes in module_28 www.broad.mit.e...
Broad module_125 View Gene Set 7.781e-10 42 2.944e-08 12 Genes in module_125 www.broad.mit.e...
Broad module_57 View Gene Set 1.388e-09 54 4.847e-08 13 Genes in module_57 www.broad.mit.e...
Broad module_124 View Gene Set 4.358e-09 92 1.413e-07 14 Genes in module_124 www.broad.mit.e...
Broad module_83 View Gene Set 5.6e-09 296 1.695e-07 15 Genes in module_83 www.broad.mit.e...
Broad module_403 View Gene Set 8.207e-09 44 2.329e-07 16 Genes in module_403 www.broad.mit.e...
Broad module_197 View Gene Set 1.401e-08 170 3.74e-07 17 Genes in module_197 www.broad.mit.e...
Broad module_337 View Gene Set 3.458e-08 59 8.721e-07 18 Genes in module_337 www.broad.mit.e...
Broad module_126 View Gene Set 1.656e-07 173 3.957e-06 19 Genes in module_126 www.broad.mit.e...
Broad module_61 View Gene Set 2.156e-07 50 4.894e-06 20 Genes in module_61 www.broad.mit.e...
Broad module_392 View Gene Set 3.971e-07 18 8.449e-06 21 Genes in module_392 www.broad.mit.e...
Broad module_397 View Gene Set 4.094e-07 114 8.449e-06 21 Genes in module_397 www.broad.mit.e...
Broad module_219 View Gene Set 4.852e-07 26 9.578e-06 23 Genes in module_219 www.broad.mit.e...
Broad module_315 View Gene Set 7.662e-07 15 1.449e-05 24 Genes in module_315 www.broad.mit.e...
Broad module_278 View Gene Set 3.412e-06 34 6.197e-05 25 Genes in module_278 www.broad.mit.e...
Broad module_35 View Gene Set 5.72e-06 16 9.988e-05 26 Genes in module_35 www.broad.mit.e...
Broad module_50 View Gene Set 7.961e-06 13 0.0001291 27 Genes in module_50 www.broad.mit.e...
Broad module_320 View Gene Set 7.698e-06 19 0.0001291 27 Genes in module_320 www.broad.mit.e...
Broad module_388 View Gene Set 8.766e-06 17 0.0001372 29 Genes in module_388 www.broad.mit.e...
Broad module_352 View Gene Set 1.073e-05 17 0.0001624 30 Genes in module_352 www.broad.mit.e...
Broad module_110 View Gene Set 1.204e-05 15 0.0001764 31 Genes in module_110 www.broad.mit.e...
Broad module_133 View Gene Set 1.614e-05 15 0.0002289 32 Genes in module_133 www.broad.mit.e...
Broad module_160 View Gene Set 1.819e-05 15 0.0002502 33 Genes in module_160 www.broad.mit.e...
Broad module_102 View Gene Set 5.364e-05 18 0.0007162 34 Genes in module_102 www.broad.mit.e...
Broad module_457 View Gene Set 0.0001641 9 0.002129 35 Genes in module_457 www.broad.mit.e...
Broad module_189 View Gene Set 0.0002505 23 0.003159 36 Genes in module_189 www.broad.mit.e...
Broad module_168 View Gene Set 0.0003088 22 0.003789 37 Genes in module_168 www.broad.mit.e...
Broad module_222 View Gene Set 0.0003181 22 0.0038 38 Genes in module_222 www.broad.mit.e...
Broad module_451 View Gene Set 0.0004003 29 0.00466 39 Genes in module_451 www.broad.mit.e...
Broad module_3 View Gene Set 0.0004328 374 0.004913 40 Genes in module_3 www.broad.mit.e...
Broad module_90 View Gene Set 0.0004621 17 0.005117 41 Genes in module_90 www.broad.mit.e...
Broad module_115 View Gene Set 0.000656 27 0.006769 42 Genes in module_115 www.broad.mit.e...
Broad module_127 View Gene Set 0.0006268 26 0.006769 42 Genes in module_127 www.broad.mit.e...
Broad module_421 View Gene Set 0.0006551 23 0.006769 42 Genes in module_421 www.broad.mit.e...
Broad module_8 View Gene Set 0.001599 403 0.01614 45 Genes in module_8 www.broad.mit.e...
Broad module_528 View Gene Set 0.001808 10 0.01785 46 Genes in module_528 www.broad.mit.e...
Broad module_53 View Gene Set 0.001901 389 0.01836 47 Genes in module_53 www.broad.mit.e...
Broad module_203 View Gene Set 0.002196 16 0.02077 48 Genes in module_203 www.broad.mit.e...
Broad module_233 View Gene Set 0.002312 22 0.02142 49 Genes in module_233 www.broad.mit.e...
Broad module_16 View Gene Set 0.002723 495 0.02473 50 Genes in module_16 www.broad.mit.e...
Broad module_299 View Gene Set 0.002889 33 0.02572 51 Genes in module_299 www.broad.mit.e...
Broad module_471 View Gene Set 0.00348 9 0.03038 52 Genes in module_471 www.broad.mit.e...
Broad module_18 View Gene Set 0.003987 434 0.03416 53 Genes in module_18 www.broad.mit.e...
Broad module_149 View Gene Set 0.004201 36 0.03532 54 Genes in module_149 www.broad.mit.e...
Broad module_114 View Gene Set 0.005563 314 0.0451 55 Genes in module_114 www.broad.mit.e...
Broad module_538 View Gene Set 0.005488 8 0.0451 55 Genes in module_538 www.broad.mit.e...
Broad module_552 View Gene Set 0.005812 18 0.04629 57 Genes in module_552 www.broad.mit.e...

Gene Set Collection: Broad.c5.BP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 7.311e-27 1197 6.031e-24 1 Genes annotated by the GO term GO:0006139. The chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad RNA_METABOLIC_PROCESS View Gene Set 2.164e-21 801 8.927e-19 2 Genes annotated by the GO term GO:0016070. The chemical reactions and pathways involving RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. www.broad.mit.e...
Broad RNA_PROCESSING View Gene Set 8.422e-19 147 2.316e-16 3 Genes annotated by the GO term GO:0006396. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. www.broad.mit.e...
Broad CELL_CYCLE_PROCESS View Gene Set 1.725e-16 187 3.558e-14 4 Genes annotated by the GO term GO:0022402. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. www.broad.mit.e...
Broad M_PHASE View Gene Set 5.991e-15 111 9.886e-13 5 Genes annotated by the GO term GO:0000279. Progression through M phase the part of the cell cycle comprising nuclear division. www.broad.mit.e...
Broad BIOPOLYMER_METABOLIC_PROCESS View Gene Set 4.11e-14 1623 5.651e-12 6 Genes annotated by the GO term GO:0043283. The chemical reactions and pathways involving biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. www.broad.mit.e...
Broad CELL_CYCLE_PHASE View Gene Set 3.692e-13 167 4.351e-11 7 Genes annotated by the GO term GO:0022403. A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. www.broad.mit.e...
Broad M_PHASE_OF_MITOTIC_CELL_CYCLE View Gene Set 4.287e-13 83 4.421e-11 8 Genes annotated by the GO term GO:0000087. Progression through M phase the part of the mitotic cell cycle during which mitosis takes place. www.broad.mit.e...
Broad MITOSIS View Gene Set 9.539e-13 81 8.744e-11 9 Genes annotated by the GO term GO:0007067. Progression through mitosis the division of the eukaryotic cell nucleus to produce two daughter nuclei that usually contain the identical chromosome complement to their mother. www.broad.mit.e...
Broad MITOTIC_CELL_CYCLE View Gene Set 3.776e-12 148 3.115e-10 10 Genes annotated by the GO term GO:0000278. Progression through the phases of the mitotic cell cycle the most common eukaryotic cell cycle which canonically comprises four successive phases called G1 S G2 and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division or G1 and G2 phases may be absent. www.broad.mit.e...
Broad RNA_SPLICING View Gene Set 1.79e-11 73 1.342e-09 11 Genes annotated by the GO term GO:0008380. The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. www.broad.mit.e...
Broad CELL_CYCLE_GO_0007049 View Gene Set 4.167e-10 304 2.865e-08 12 Genes annotated by the GO term GO:0007049. The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. www.broad.mit.e...
Broad MRNA_METABOLIC_PROCESS View Gene Set 5.994e-10 70 3.804e-08 13 Genes annotated by the GO term GO:0016071. The chemical reactions and pathways involving mRNA messenger RNA which is responsible for carrying the coded genetic 'message' transcribed from DNA to sites of protein assembly at the ribosomes. www.broad.mit.e...
Broad MRNA_PROCESSING_GO_0006397 View Gene Set 9.62e-10 59 5.669e-08 14 Genes annotated by the GO term GO:0006397. Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. www.broad.mit.e...
Broad TRANSCRIPTION_DNA_DEPENDENT View Gene Set 2.514e-09 623 1.296e-07 15 Genes annotated by the GO term GO:0006351. The synthesis of RNA on a template of DNA. www.broad.mit.e...
Broad RNA_BIOSYNTHETIC_PROCESS View Gene Set 2.384e-09 625 1.296e-07 15 Genes annotated by the GO term GO:0032774. The chemical reactions and pathways resulting in the formation of RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. www.broad.mit.e...
Broad TRANSCRIPTION View Gene Set 2.856e-09 738 1.386e-07 17 Genes annotated by the GO term GO:0006350. The synthesis of either RNA on a template of DNA or DNA on a template of RNA. www.broad.mit.e...
Broad DNA_METABOLIC_PROCESS View Gene Set 1.611e-08 253 7.386e-07 18 Genes annotated by the GO term GO:0006259. The chemical reactions and pathways involving DNA deoxyribonucleic acid one of the two main types of nucleic acid consisting of a long unbranched macromolecule formed from one or more commonly two strands of linked deoxyribonucleotides. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY View Gene Set 1.954e-08 74 8.483e-07 19 Genes annotated by the GO term GO:0022613. The cellular process by which a complex containing RNA and proteins is synthesized aggregates and bonds together. www.broad.mit.e...
Broad TRANSLATION View Gene Set 3.431e-08 177 1.415e-06 20 Genes annotated by the GO term GO:0006412. The chemical reactions and pathways resulting in the formation of a protein. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. www.broad.mit.e...
Broad TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 6.364e-07 449 2.5e-05 21 Genes annotated by the GO term GO:0006366. The synthesis of RNA from a DNA template by RNA polymerase II (Pol II) originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). www.broad.mit.e...
Broad CHROMOSOME_ORGANIZATION_AND_BIOGENESIS View Gene Set 1.351e-06 117 5.068e-05 22 Genes annotated by the GO term GO:0051276. A process that is carried out at the cellular level that results in the formation arrangement of constituent parts or disassembly of chromosomes structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. www.broad.mit.e...
Broad REGULATION_OF_MITOSIS View Gene Set 2.137e-06 40 7.666e-05 23 Genes annotated by the GO term GO:0007088. Any process that modulates the frequency rate or extent of mitosis. www.broad.mit.e...
Broad CELL_CYCLE_CHECKPOINT_GO_0000075 View Gene Set 4.814e-06 47 0.0001655 24 Genes annotated by the GO term GO:0000075. A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. www.broad.mit.e...
Broad RIBOSOME_BIOGENESIS_AND_ASSEMBLY View Gene Set 5.2e-06 14 0.0001716 25 Genes annotated by the GO term GO:0042254. The process of the formation of the constituents of the ribosome subunits their assembly and their transport to the sites of protein synthesis. www.broad.mit.e...
Broad PROTEIN_RNA_COMPLEX_ASSEMBLY View Gene Set 6.599e-06 59 0.0002094 26 Genes annotated by the GO term GO:0022618. The aggregation arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. www.broad.mit.e...
Broad SPINDLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 1.41e-05 10 0.0004308 27 Genes annotated by the GO term GO:0007051. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the spindle the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. www.broad.mit.e...
Broad DNA_REPLICATION View Gene Set 1.994e-05 101 0.0005874 28 Genes annotated by the GO term GO:0006260. The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. www.broad.mit.e...
Broad REGULATION_OF_GENE_EXPRESSION View Gene Set 2.232e-05 660 0.0006147 29 Genes annotated by the GO term GO:0010468. Any process that modulates the frequency rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. www.broad.mit.e...
Broad DNA_RECOMBINATION View Gene Set 2.235e-05 47 0.0006147 29 Genes annotated by the GO term GO:0006310. The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment intrachromosomal recombination or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation conjugation transduction or F-duction. www.broad.mit.e...
Broad MITOTIC_SPINDLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 2.796e-05 9 0.0007442 31 Genes annotated by the GO term GO:0007052. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the microtubule spindle during a mitotic cell cycle. www.broad.mit.e...
Broad DNA_REPAIR View Gene Set 3.344e-05 123 0.0008359 32 Genes annotated by the GO term GO:0006281. The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations chemical mutagens fungal and bacterial toxins etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal base excision repair nucleotide excision repair photoreactivation bypass double-strand break repair pathway and mismatch repair pathway. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX_ASSEMBLY View Gene Set 3.341e-05 271 0.0008359 32 Genes annotated by the GO term GO:0065003. The aggregation arrangement and bonding together of a set of macromolecules to form a complex. www.broad.mit.e...
Broad SISTER_CHROMATID_SEGREGATION View Gene Set 3.519e-05 17 0.0008538 34 Genes annotated by the GO term GO:0000819. The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets. www.broad.mit.e...
Broad CELLULAR_COMPONENT_ASSEMBLY View Gene Set 3.637e-05 288 0.0008574 35 Genes annotated by the GO term GO:0022607. A cellular process that results in the assembly of a part of the cell. www.broad.mit.e...
Broad REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 3.84e-05 601 0.0008799 36 Genes annotated by the GO term GO:0019219. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad CELLULAR_BIOSYNTHETIC_PROCESS View Gene Set 5.412e-05 311 0.001207 37 Genes annotated by the GO term GO:0044249. The chemical reactions and pathways resulting in the formation of substances carried out by individual cells. www.broad.mit.e...
Broad RESPONSE_TO_DNA_DAMAGE_STIMULUS View Gene Set 6.202e-05 159 0.001347 38 Genes annotated by the GO term GO:0006974. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. www.broad.mit.e...
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_TRANSPORT View Gene Set 7.828e-05 31 0.001656 39 Genes annotated by the GO term GO:0015931. The directed movement of nucleobases nucleosides nucleotides and nucleic acids into out of within or between cells. www.broad.mit.e...
Broad MITOTIC_SISTER_CHROMATID_SEGREGATION View Gene Set 8.249e-05 16 0.00166 40 Genes annotated by the GO term GO:0000070. The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome composed of two sister chromatids aligns at the cell equator paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. www.broad.mit.e...
Broad RRNA_PROCESSING View Gene Set 8.092e-05 11 0.00166 40 Genes annotated by the GO term GO:0006364. Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. www.broad.mit.e...
Broad RNA_SPLICINGVIA_TRANSESTERIFICATION_REACTIONS View Gene Set 8.495e-05 27 0.001669 42 Genes annotated by the GO term GO:0000375. Splicing of RNA via a series of two transesterification reactions. www.broad.mit.e...
Broad MEIOSIS_I View Gene Set 0.0001036 19 0.001943 43 Genes annotated by the GO term GO:0007127. Progression through the first phase of meiosis in which cells divide and homologous chromosomes are paired and segregated from each other producing two daughter cells. www.broad.mit.e...
Broad RESPONSE_TO_ENDOGENOUS_STIMULUS View Gene Set 0.0001016 197 0.001943 43 Genes annotated by the GO term GO:0009719. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of an endogenous stimulus. www.broad.mit.e...
Broad PROTEIN_DNA_COMPLEX_ASSEMBLY View Gene Set 0.0001403 48 0.002572 45 Genes annotated by the GO term GO:0065004. The aggregation arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex. www.broad.mit.e...
Broad RRNA_METABOLIC_PROCESS View Gene Set 0.0001894 12 0.003396 46 Genes annotated by the GO term GO:0016072. The chemical reactions and pathways involving rRNA ribosomal RNA a structural constituent of ribosomes. www.broad.mit.e...
Broad NUCLEOCYTOPLASMIC_TRANSPORT View Gene Set 0.0001937 83 0.003401 47 Genes annotated by the GO term GO:0006913. The directed movement of molecules between the nucleus and the cytoplasm. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTION View Gene Set 0.0002221 555 0.003817 48 Genes annotated by the GO term GO:0045449. Any process that modulates the frequency rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. www.broad.mit.e...
Broad MEIOTIC_CELL_CYCLE View Gene Set 0.0002858 34 0.004813 49 Genes annotated by the GO term GO:0051321. Progression through the phases of the meiotic cell cycle in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell. www.broad.mit.e...
Broad NUCLEAR_TRANSPORT View Gene Set 0.0003217 84 0.005308 50 Genes annotated by the GO term GO:0051169. The directed movement of substances into out of or within the nucleus. www.broad.mit.e...
Broad MITOTIC_CELL_CYCLE_CHECKPOINT View Gene Set 0.0003811 21 0.005899 51 Genes annotated by the GO term GO:0007093. A signal transduction-based surveillance mechanism that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage. www.broad.mit.e...
Broad MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0003847 34 0.005899 51 Genes annotated by the GO term GO:0000226. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. www.broad.mit.e...
Broad REGULATION_OF_CELLULAR_METABOLIC_PROCESS View Gene Set 0.0003648 767 0.005899 51 Genes annotated by the GO term GO:0031323. Any process that modulates the frequency rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. www.broad.mit.e...
Broad REGULATION_OF_METABOLIC_PROCESS View Gene Set 0.0003861 779 0.005899 51 Genes annotated by the GO term GO:0019222. Any process that modulates the frequency rate or extent of the chemical reactions and pathways within a cell or an organism. www.broad.mit.e...
Broad TRANSCRIPTION_INITIATION View Gene Set 0.0004251 35 0.006377 55 Genes annotated by the GO term GO:0006352. Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT View Gene Set 0.0005577 452 0.008216 56 Genes annotated by the GO term GO:0006355. Any process that modulates the frequency rate or extent of DNA-dependent transcription. www.broad.mit.e...
Broad REGULATION_OF_RNA_METABOLIC_PROCESS View Gene Set 0.0006088 457 0.008812 57 Genes annotated by the GO term GO:0051252. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving RNA. www.broad.mit.e...
Broad RNA_EXPORT_FROM_NUCLEUS View Gene Set 0.0007334 20 0.01043 58 Genes annotated by the GO term GO:0006405. The directed movement of RNA from the nucleus to the cytoplasm. www.broad.mit.e...
Broad DNA_INTEGRITY_CHECKPOINT View Gene Set 0.0007659 23 0.01071 59 Genes annotated by the GO term GO:0031570. Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure. www.broad.mit.e...
Broad MEIOTIC_RECOMBINATION View Gene Set 0.0008017 17 0.01102 60 Genes annotated by the GO term GO:0007131. The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity. www.broad.mit.e...
Broad N_TERMINAL_PROTEIN_AMINO_ACID_MODIFICATION View Gene Set 0.0008874 6 0.012 61 Genes annotated by the GO term GO:0031365. The alteration of the N-terminal amino acid residue in a protein. www.broad.mit.e...
Broad CHROMOSOME_SEGREGATION View Gene Set 0.0009168 31 0.0122 62 Genes annotated by the GO term GO:0007059. The process by which genetic material in the form of chromosomes is organized and then physically separated and apportioned to two or more sets. www.broad.mit.e...
Broad TRNA_METABOLIC_PROCESS View Gene Set 0.001057 18 0.01384 63 Genes annotated by the GO term GO:0006399. The chemical reactions and pathways involving tRNA transfer RNA a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases the function of which has not been completely established. www.broad.mit.e...
Broad PROTEIN_CATABOLIC_PROCESS View Gene Set 0.001165 68 0.01502 64 Genes annotated by the GO term GO:0030163. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native active configuration with or without the hydrolysis of peptide bonds. www.broad.mit.e...
Broad MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.001204 16 0.01528 65 Genes annotated by the GO term GO:0031023. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a microtubule organizing center a structure from which microtubules grow. www.broad.mit.e...
Broad TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 0.001261 29 0.01576 66 Genes annotated by the GO term GO:0006367. Processes involved in starting transcription from the RNA polymerase II promoter. www.broad.mit.e...
Broad DNA_PACKAGING View Gene Set 0.001806 34 0.02224 67 Genes annotated by the GO term GO:0006323. Any process by which DNA and associated proteins are formed into a compact orderly structure. www.broad.mit.e...
Broad CELL_DIVISION View Gene Set 0.002725 21 0.03226 68 Genes annotated by the GO term GO:0051301. The processes resulting in the physical partitioning and separation of a cell into daughter cells. www.broad.mit.e...
Broad NLS_BEARING_SUBSTRATE_IMPORT_INTO_NUCLEUS View Gene Set 0.00273 12 0.03226 68 Genes annotated by the GO term GO:0006607. The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus across the nuclear membrane. www.broad.mit.e...
Broad ANDROGEN_RECEPTOR_SIGNALING_PATHWAY View Gene Set 0.002737 12 0.03226 68 Genes annotated by the GO term GO:0030521. Any series of molecular signals generated as a consequence of an androgen binding to its receptor. www.broad.mit.e...
Broad BIOPOLYMER_CATABOLIC_PROCESS View Gene Set 0.002853 115 0.03316 71 Genes annotated by the GO term GO:0043285. The chemical reactions and pathways resulting in the breakdown of biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. www.broad.mit.e...
Broad TRANSLATIONAL_INITIATION View Gene Set 0.003072 39 0.0352 72 Genes annotated by the GO term GO:0006413. The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome mRNA and an initiation complex that contains the first aminoacyl-tRNA. www.broad.mit.e...
Broad STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY View Gene Set 0.00341 20 0.03853 73 Genes annotated by the GO term GO:0030518. Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor. www.broad.mit.e...
Broad CENTROSOME_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.003694 15 0.04064 74 Genes annotated by the GO term GO:0051297. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a centrosome a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 0.003666 285 0.04064 74 Genes annotated by the GO term GO:0006357. Any process that modulates the frequency rate or extent of transcription from an RNA polymerase II promoter. www.broad.mit.e...
Broad INTRACELLULAR_RECEPTOR_MEDIATED_SIGNALING_PATHWAY View Gene Set 0.003773 21 0.04096 76 Genes annotated by the GO term GO:0030522. Any series of molecular signals initiated by a ligand entering the target cell where it binds to an intracellular receptor. www.broad.mit.e...
Broad CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS View Gene Set 0.003864 103 0.0414 77 Genes annotated by the GO term GO:0044265. The chemical reactions and pathways resulting in the breakdown of a macromolecule any large molecule including proteins nucleic acids and carbohydrates as carried out by individual cells. www.broad.mit.e...
Broad NUCLEAR_EXPORT View Gene Set 0.00401 31 0.04242 78 Genes annotated by the GO term GO:0051168. The directed movement of substances out of the nucleus. www.broad.mit.e...
Broad S_PHASE View Gene Set 0.004298 14 0.04489 79 Genes annotated by the GO term GO:0051320. Progression through S phase the part of the cell cycle during which DNA synthesis takes place. www.broad.mit.e...
Broad SPLICEOSOME_ASSEMBLY View Gene Set 0.004474 13 0.04614 80 Genes annotated by the GO term GO:0000245. The aggregation arrangement and bonding together of the spliceosome a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. www.broad.mit.e...

Gene Set Collection: Broad.c5.CC

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad NUCLEUS View Gene Set 1.208e-34 1353 2.814e-32 1 Genes annotated by the GO term GO:0005634. A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells the nucleus contains all of the cell's chromosomes except the organellar chromosomes and is the site of RNA synthesis and processing. In some species or in specialized cell types RNA metabolism or DNA replication may be absent. www.broad.mit.e...
Broad NUCLEAR_PART View Gene Set 1.036e-29 543 1.207e-27 2 Genes annotated by the GO term GO:0044428. Any constituent part of the nucleus a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX View Gene Set 1.035e-17 129 8.036e-16 3 Genes annotated by the GO term GO:0030529. A macromolecular complex containing both protein and RNA molecules. www.broad.mit.e...
Broad NUCLEAR_LUMEN View Gene Set 4.567e-17 365 2.66e-15 4 Genes annotated by the GO term GO:0031981. The volume enclosed by the nuclear inner membrane. www.broad.mit.e...
Broad ORGANELLE_LUMEN View Gene Set 1.266e-15 434 4.917e-14 5 Genes annotated by the GO term GO:0043233. The volume enclosed by the membranes of a particular organelle e.g. endoplasmic reticulum lumen or the space between the two lipid bilayers of a double membrane surrounding an organelle e.g. nuclear membrane lumen. www.broad.mit.e...
Broad MEMBRANE_ENCLOSED_LUMEN View Gene Set 1.266e-15 434 4.917e-14 5 Genes annotated by the GO term GO:0031974. The enclosed volume within a sealed membrane or between two sealed membranes. www.broad.mit.e...
Broad INTRACELLULAR_ORGANELLE_PART View Gene Set 1.408e-13 1144 4.687e-12 7 Genes annotated by the GO term GO:0044446. A constituent part of an intracellular organelle an organized structure of distinctive morphology and function occurring within the cell. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad ORGANELLE_PART View Gene Set 3.386e-13 1149 9.863e-12 8 Genes annotated by the GO term GO:0044422. Any constituent part of an organelle an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad NUCLEOLUS View Gene Set 5.459e-11 116 1.413e-09 9 Genes annotated by the GO term GO:0005730. A small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA the processing of this RNA into 5.8S 18S and 28S components of ribosomal RNA and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX View Gene Set 1.32e-10 914 3.076e-09 10 Genes annotated by the GO term GO:0032991. A stable assembly of two or more macromolecules i.e. proteins nucleic acids carbohydrates or lipids in which the constituent parts function together. www.broad.mit.e...
Broad CHROMOSOME View Gene Set 1.336e-09 122 2.83e-08 11 Genes annotated by the GO term GO:0005694. A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. www.broad.mit.e...
Broad NUCLEOPLASM View Gene Set 1.649e-09 266 3.203e-08 12 Genes annotated by the GO term GO:0005654. That part of the nuclear content other than the chromosomes or the nucleolus. www.broad.mit.e...
Broad SPLICEOSOME View Gene Set 1.805e-09 44 3.235e-08 13 Genes annotated by the GO term GO:0005681. A ribonucleoprotein complex containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron. www.broad.mit.e...
Broad CHROMOSOMAL_PART View Gene Set 3.38e-08 95 5.625e-07 14 Genes annotated by the GO term GO:0044427. Any constituent part of a chromosome a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. www.broad.mit.e...
Broad NON_MEMBRANE_BOUND_ORGANELLE View Gene Set 4.451e-08 613 6.482e-07 15 Genes annotated by the GO term GO:0043228. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane. Includes ribosomes the cytoskeleton and chromosomes. www.broad.mit.e...
Broad INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE View Gene Set 4.451e-08 613 6.482e-07 15 Genes annotated by the GO term GO:0043232. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes the cytoskeleton and chromosomes. www.broad.mit.e...
Broad PORE_COMPLEX View Gene Set 6.816e-07 34 8.859e-06 17 Genes annotated by the GO term GO:0046930. Any small opening in a membrane that allows the passage of gases and/or liquids. www.broad.mit.e...
Broad NUCLEOPLASM_PART View Gene Set 6.844e-07 202 8.859e-06 17 Genes annotated by the GO term GO:0044451. Any constituent part of the nucleoplasm that part of the nuclear content other than the chromosomes or the nucleolus. www.broad.mit.e...
Broad SPINDLE View Gene Set 7.618e-07 37 9.343e-06 19 Genes annotated by the GO term GO:0005819. The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. www.broad.mit.e...
Broad NUCLEAR_PORE View Gene Set 1.128e-06 29 1.314e-05 20 Genes annotated by the GO term GO:0005643. Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell where the inner and outer nuclear membranes are joined. www.broad.mit.e...
Broad PROTEASOME_COMPLEX View Gene Set 1.643e-06 23 1.823e-05 21 Genes annotated by the GO term GO:0000502. A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. www.broad.mit.e...
Broad ENVELOPE View Gene Set 2.633e-06 165 2.667e-05 22 Genes annotated by the GO term GO:0031975. A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers and may include a cell wall layer also includes the space between layers. www.broad.mit.e...
Broad ORGANELLE_ENVELOPE View Gene Set 2.633e-06 165 2.667e-05 22 Genes annotated by the GO term GO:0031967. A double membrane structure enclosing an organelle including two lipid bilayers and the region between them. In some cases an organelle envelope may have more than two membranes. www.broad.mit.e...
Broad CONDENSED_CHROMOSOME View Gene Set 3.083e-06 32 2.993e-05 24 Genes annotated by the GO term GO:0000793. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. www.broad.mit.e...
Broad NUCLEAR_ENVELOPE View Gene Set 3.838e-06 71 3.577e-05 25 Genes annotated by the GO term GO:0005635. The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space a gap of width 20-40 nm (also called the perinuclear space). www.broad.mit.e...
Broad CHROMOSOMEPERICENTRIC_REGION View Gene Set 1.664e-05 31 0.0001491 26 Genes annotated by the GO term GO:0000775. The central region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes this region corresponds to a single area of the chromosome whereas in holocentric chromosomes it is evenly distributed along the chromosome. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE View Gene Set 2.445e-05 48 0.0001991 27 Genes annotated by the GO term GO:0031965. Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. www.broad.mit.e...
Broad NUCLEOLAR_PART View Gene Set 2.39e-05 16 0.0001991 27 Genes annotated by the GO term GO:0044452. Any constituent part of a nucleolus a small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE_PART View Gene Set 2.477e-05 40 0.0001991 27 Genes annotated by the GO term GO:0044453. Any constituent part of the nuclear membrane the envelope that surrounds the nucleus of eukaryotic cells. www.broad.mit.e...
Broad CONDENSED_NUCLEAR_CHROMOSOME View Gene Set 2.569e-05 17 0.0001996 30 Genes annotated by the GO term GO:0000794. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure that remains in the nucleus. www.broad.mit.e...
Broad SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX View Gene Set 4.419e-05 20 0.0003321 31 Genes annotated by the GO term GO:0030532. A complex composed of RNA of the small nuclear RNA (snRNA) class and protein found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain e.g. U1 snRNP or U4/U6 snRNP. Many but not all of these complexes are involved in splicing of nuclear mRNAs. www.broad.mit.e...
Broad SPINDLE_MICROTUBULE View Gene Set 4.819e-05 15 0.0003509 32 Genes annotated by the GO term GO:0005876. Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. www.broad.mit.e...
Broad MITOCHONDRION View Gene Set 5.783e-05 335 0.0004083 33 Genes annotated by the GO term GO:0005739. A semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. www.broad.mit.e...
Broad PROTEIN_COMPLEX View Gene Set 8.449e-05 799 0.000579 34 Genes annotated by the GO term GO:0043234. Any protein group composed of two or more subunits which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. www.broad.mit.e...
Broad KINETOCHORE View Gene Set 0.0001409 25 0.0009382 35 Genes annotated by the GO term GO:0000776. A multisubunit complex that is located at the pericentric region of DNA and provides an attachment point for the spindle microtubules. www.broad.mit.e...
Broad ORGANELLAR_RIBOSOME View Gene Set 0.0001907 22 0.001169 36 Genes annotated by the GO term GO:0000313. A ribosome contained within a subcellular organelle. www.broad.mit.e...
Broad RIBOSOME View Gene Set 0.0001904 39 0.001169 36 Genes annotated by the GO term GO:0005840. An intracellular organelle about 200 A in diameter consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits one large and one small each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients expressed in Svedberg units (symbol: S). Hence the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes eukaryotes mitochondria and chloroplasts have characteristically distinct ribosomal proteins. www.broad.mit.e...
Broad MITOCHONDRIAL_RIBOSOME View Gene Set 0.0001907 22 0.001169 36 Genes annotated by the GO term GO:0005761. A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. www.broad.mit.e...
Broad SPINDLE_POLE View Gene Set 0.0002983 17 0.001782 39 Genes annotated by the GO term GO:0000922. Either of the ends of a spindle where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules spindle microtubules and astral microtubules. www.broad.mit.e...
Broad NUCLEAR_CHROMOSOME View Gene Set 0.0004007 53 0.002334 40 Genes annotated by the GO term GO:0000228. A chromosome found in the nucleus of a eukaryotic cell. www.broad.mit.e...
Broad RIBOSOMAL_SUBUNIT View Gene Set 0.0006258 20 0.003557 41 Genes annotated by the GO term GO:0033279. Either of the two ribonucleoprotein complexes that associate to form a ribosome. www.broad.mit.e...
Broad MITOCHONDRIAL_PART View Gene Set 0.0006966 140 0.003865 42 Genes annotated by the GO term GO:0044429. Any constituent part of a mitochondrion a semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. www.broad.mit.e...
Broad MICROTUBULE_ORGANIZING_CENTER View Gene Set 0.001047 64 0.005675 43 Genes annotated by the GO term GO:0005815. A region in a eukaryotic cell such as a centrosome or basal body from which microtubules grow. www.broad.mit.e...
Broad TRANSCRIPTION_FACTOR_COMPLEX View Gene Set 0.00164 84 0.008683 44 Genes annotated by the GO term GO:0005667. Any complex distinct from RNA polymerase including one or more polypeptides capable of binding DNA at promoters or at cis-acting regulatory sequences and regulating transcription. www.broad.mit.e...
Broad ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.001848 11 0.009161 45 Genes annotated by the GO term GO:0000314. The smaller of the two subunits of an organellar ribosome. www.broad.mit.e...
Broad MITOCHONDRIAL_SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.001848 11 0.009161 45 Genes annotated by the GO term GO:0005763. The smaller of the two subunits of a mitochondrial ribosome. www.broad.mit.e...
Broad SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.001848 11 0.009161 45 Genes annotated by the GO term GO:0015935. The smaller of the two subunits of a ribosome. www.broad.mit.e...
Broad HETEROGENEOUS_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX View Gene Set 0.002369 9 0.0115 48 Genes annotated by the GO term GO:0030530. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II that which is translated into protein) with protein which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA. www.broad.mit.e...
Broad CHROMATIN View Gene Set 0.002903 35 0.0138 49 Genes annotated by the GO term GO:0000785. The ordered and organized complex of DNA and protein that forms the chromosome. www.broad.mit.e...
Broad EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX View Gene Set 0.003228 10 0.01504 50 Genes annotated by the GO term GO:0005852. A complex of several polypeptides that plays at least two important roles in protein synthesis: First eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. www.broad.mit.e...
Broad CENTROSOME View Gene Set 0.003378 55 0.01543 51 Genes annotated by the GO term GO:0005813. A structure comprised of a core structure (in most organisms a pair of centrioles) and peripheral material from which a microtubule-based structure such as a spindle apparatus is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells though in animal cells it changes continually during the cell-division cycle. www.broad.mit.e...
Broad MITOCHONDRIAL_MATRIX View Gene Set 0.003782 46 0.01663 52 Genes annotated by the GO term GO:0005759. The gel-like material with considerable fine structure that lies in the matrix space or lumen of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and in some organisms the enzymes concerned with fatty-acid oxidation. www.broad.mit.e...
Broad MITOCHONDRIAL_LUMEN View Gene Set 0.003782 46 0.01663 52 Genes annotated by the GO term GO:0031980. The volume enclosed by the mitochondrial inner membrane. www.broad.mit.e...
Broad MICROTUBULE View Gene Set 0.004533 31 0.01956 54 Genes annotated by the GO term GO:0005874. Any of the long generally straight hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation e.g. in the spindle. www.broad.mit.e...
Broad MITOCHONDRIAL_MEMBRANE View Gene Set 0.005752 85 0.02437 55 Genes annotated by the GO term GO:0031966. Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. www.broad.mit.e...
Broad ORGANELLE_INNER_MEMBRANE View Gene Set 0.00865 74 0.03599 56 Genes annotated by the GO term GO:0019866. The inner i.e. lumen-facing lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites. www.broad.mit.e...
Broad NUCLEAR_BODY View Gene Set 0.009352 31 0.03823 57 Genes annotated by the GO term GO:0016604. Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. www.broad.mit.e...

Gene Set Collection: Broad.c5.MF

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad RNA_BINDING View Gene Set 1.536e-19 236 6.084e-17 1 Genes annotated by the GO term GO:0003723. Interacting selectively with an RNA molecule or a portion thereof. www.broad.mit.e...
Broad DNA_BINDING View Gene Set 1.788e-09 587 3.54e-07 2 Genes annotated by the GO term GO:0003677. Interacting selectively with DNA (deoxyribonucleic acid). www.broad.mit.e...
Broad STRUCTURAL_CONSTITUENT_OF_RIBOSOME View Gene Set 9.596e-09 80 1.267e-06 3 Genes annotated by the GO term GO:0003735. The action of a molecule that contributes to the structural integrity of the ribosome. www.broad.mit.e...
Broad TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING View Gene Set 2.422e-08 39 2.398e-06 4 Genes annotated by the GO term GO:0008135. Functions during translation by binding nucleic acids during polypeptide synthesis at the ribosome. www.broad.mit.e...
Broad TRANSLATION_REGULATOR_ACTIVITY View Gene Set 1.51e-07 41 1.196e-05 5 Genes annotated by the GO term GO:0045182. Any substance involved in the initiation activation perpetuation repression or termination of polypeptide synthesis at the ribosome. www.broad.mit.e...
Broad TRANSLATION_INITIATION_FACTOR_ACTIVITY View Gene Set 3.042e-06 24 0.0002008 6 Genes annotated by the GO term GO:0003743. Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. www.broad.mit.e...
Broad HELICASE_ACTIVITY View Gene Set 2.505e-05 49 0.001417 7 Genes annotated by the GO term GO:0004386. Catalysis of the unwinding of a DNA or RNA duplex. www.broad.mit.e...
Broad RNA_HELICASE_ACTIVITY View Gene Set 3.58e-05 24 0.001772 8 Genes annotated by the GO term GO:0003724. Catalysis of the unwinding of an RNA helix. www.broad.mit.e...
Broad RNA_SPLICING_FACTOR_ACTIVITYTRANSESTERIFICATION_MECHANISM View Gene Set 5.198e-05 14 0.002287 9 Genes annotated by the GO term GO:0031202. An activity which binds RNA and functions to assist splicing of substrate RNA(s) by facilitating the formation and stabilization of a catalytic conformation in which the splice junctions of the RNA(s) to be spliced are positioned for a transesterification reaction that occurs between two sites within the RNA(s) to be spliced. www.broad.mit.e...
Broad SINGLE_STRANDED_DNA_BINDING View Gene Set 5.928e-05 34 0.002348 10 Genes annotated by the GO term GO:0003697. Interacting selectively with single-stranded DNA. www.broad.mit.e...
Broad ATP_DEPENDENT_HELICASE_ACTIVITY View Gene Set 7.356e-05 26 0.002648 11 Genes annotated by the GO term GO:0008026. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the unwinding of a DNA or RNA helix. www.broad.mit.e...
Broad LIGASE_ACTIVITY_FORMING_CARBON_NITROGEN_BONDS View Gene Set 0.0001419 68 0.004682 12 Genes annotated by the GO term GO:0016879. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. www.broad.mit.e...
Broad STRUCTURE_SPECIFIC_DNA_BINDING View Gene Set 0.0002495 55 0.0076 13 Genes annotated by the GO term GO:0043566. Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. www.broad.mit.e...
Broad DNA_DEPENDENT_ATPASE_ACTIVITY View Gene Set 0.0002753 22 0.007788 14 Genes annotated by the GO term GO:0008094. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single- or double-stranded DNA; drives another reaction. www.broad.mit.e...
Broad LIGASE_ACTIVITY View Gene Set 0.0003256 97 0.008595 15 Genes annotated by the GO term GO:0016874. Catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. www.broad.mit.e...
Broad CHROMATIN_BINDING View Gene Set 0.0003853 32 0.009537 16 Genes annotated by the GO term GO:0003682. Interacting selectively with chromatin the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. www.broad.mit.e...
Broad RNA_DEPENDENT_ATPASE_ACTIVITY View Gene Set 0.000411 18 0.009574 17 Genes annotated by the GO term GO:0008186. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of RNA; drives another reaction. www.broad.mit.e...
Broad UNFOLDED_PROTEIN_BINDING View Gene Set 0.0005495 41 0.01209 18 Genes annotated by the GO term GO:0051082. Interacting selectively with an unfolded protein. www.broad.mit.e...
Broad ATP_DEPENDENT_RNA_HELICASE_ACTIVITY View Gene Set 0.0005851 17 0.0122 19 Genes annotated by the GO term GO:0004004. Catalysis of the reaction: ATP + H2O = ADP + phosphate driving the unwinding of an RNA helix. www.broad.mit.e...
Broad THYROID_HORMONE_RECEPTOR_BINDING View Gene Set 0.0007071 17 0.014 20 Genes annotated by the GO term GO:0046966. Interacting selectively with a thyroid hormone receptor. www.broad.mit.e...
Broad LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS View Gene Set 0.001086 14 0.02048 21 Genes annotated by the GO term GO:0016875. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. www.broad.mit.e...
Broad DNA_HELICASE_ACTIVITY View Gene Set 0.001578 24 0.02717 22 Genes annotated by the GO term GO:0003678. Catalysis of the unwinding of a DNA duplex. www.broad.mit.e...
Broad NUCLEOTIDYLTRANSFERASE_ACTIVITY View Gene Set 0.00154 47 0.02717 22 Genes annotated by the GO term GO:0016779. Catalysis of the transfer of a nucleotidyl group to a reactant. www.broad.mit.e...
Broad HISTONE_ACETYLTRANSFERASE_ACTIVITY View Gene Set 0.00167 16 0.02755 24 Genes annotated by the GO term GO:0004402. Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone. www.broad.mit.e...
Broad TRANSCRIPTION_ACTIVATOR_ACTIVITY View Gene Set 0.002067 169 0.03033 25 Genes annotated by the GO term GO:0016563. Any transcription regulator activity required for initiation or upregulation of transcription. www.broad.mit.e...
Broad HORMONE_RECEPTOR_BINDING View Gene Set 0.002044 29 0.03033 25 Genes annotated by the GO term GO:0051427. Interacting selectively with a receptor for hormones. www.broad.mit.e...
Broad ENDONUCLEASE_ACTIVITY_GO_0016893 View Gene Set 0.002068 11 0.03033 25 Genes annotated by the GO term GO:0016893. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. www.broad.mit.e...
Broad RIBONUCLEASE_ACTIVITY View Gene Set 0.002179 25 0.03082 28 Genes annotated by the GO term GO:0004540. Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. www.broad.mit.e...
Broad ATP_DEPENDENT_DNA_HELICASE_ACTIVITY View Gene Set 0.003579 11 0.04887 29 Genes annotated by the GO term GO:0004003. Catalysis of the reaction: ATP + H2O = ADP + phosphate driving the unwinding of the DNA helix. www.broad.mit.e...

Gene Set Collection: PMID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
PMID 15635413 View Gene Set 1.207e-52 421 3.027e-49 1 Nucleolar proteome dynamics. www.ncbi.nlm.ni...
PMID 17643375 View Gene Set 1.406e-37 391 1.763e-34 2 Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. www.ncbi.nlm.ni...
PMID 11790298 View Gene Set 7.745e-34 208 6.472e-31 3 Directed proteomic analysis of the human nucleolus. www.ncbi.nlm.ni...
PMID 12429849 View Gene Set 1.609e-32 106 1.008e-29 4 Functional proteomic analysis of human nucleolus. www.ncbi.nlm.ni...
PMID 16565220 View Gene Set 3.002e-32 210 1.505e-29 5 Phosphoproteome analysis of the human mitotic spindle. www.ncbi.nlm.ni...
PMID 15302935 View Gene Set 9.714e-31 773 4.059e-28 6 Large-scale characterization of HeLa cell nuclear phosphoproteins. www.ncbi.nlm.ni...
PMID 16964243 View Gene Set 5.938e-24 504 2.127e-21 7 A probability-based approach for high-throughput protein phosphorylation analysis and site localization. www.ncbi.nlm.ni...
PMID 12226669 View Gene Set 1.061e-23 108 3.324e-21 8 Comprehensive proteomic analysis of the human spliceosome. www.ncbi.nlm.ni...
PMID 11991638 View Gene Set 4.185e-17 74 1.166e-14 9 Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. www.ncbi.nlm.ni...
PMID 12706105 View Gene Set 4.778e-14 182 1.198e-11 10 Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. www.ncbi.nlm.ni...
PMID 14559993 View Gene Set 6.728e-14 51 1.533e-11 11 Regulation of alternative splicing by SRrp86 and its interacting proteins. www.ncbi.nlm.ni...
PMID 12791267 View Gene Set 2.572e-11 50 5.374e-09 12 Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. www.ncbi.nlm.ni...
PMID 11285280 View Gene Set 3.199e-11 62 6.168e-09 13 Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. www.ncbi.nlm.ni...
PMID 15592455 View Gene Set 5.059e-11 317 9.059e-09 14 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. www.ncbi.nlm.ni...
PMID 12859895 View Gene Set 2.274e-10 47 3.8e-08 15 Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. www.ncbi.nlm.ni...
PMID 10893419 View Gene Set 4.014e-10 41 5.297e-08 16 Degradation of HIV-1 integrase by the N-end rule pathway. www.ncbi.nlm.ni...
PMID 12419264 View Gene Set 4.014e-10 41 5.297e-08 16 The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing. www.ncbi.nlm.ni...
PMID 14550573 View Gene Set 4.014e-10 41 5.297e-08 16 Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits. www.ncbi.nlm.ni...
PMID 9079628 View Gene Set 4.014e-10 41 5.297e-08 16 HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation. www.ncbi.nlm.ni...
PMID 20085707 View Gene Set 6.456e-10 42 8.092e-08 20 Aire's partners in the molecular control of immunological tolerance. www.ncbi.nlm.ni...
PMID 11543634 View Gene Set 9.066e-10 58 9.488e-08 21 The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. www.ncbi.nlm.ni...
PMID 12167863 View Gene Set 1.514e-09 43 9.488e-08 21 Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. www.ncbi.nlm.ni...
PMID 12719574 View Gene Set 1.223e-09 42 9.488e-08 21 Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions. www.ncbi.nlm.ni...
PMID 12750511 View Gene Set 1.223e-09 42 9.488e-08 21 Hypermutation of HIV-1 DNA in the absence of the Vif protein. www.ncbi.nlm.ni...
PMID 12808465 View Gene Set 1.514e-09 43 9.488e-08 21 The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. www.ncbi.nlm.ni...
PMID 12808466 View Gene Set 1.514e-09 43 9.488e-08 21 Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. www.ncbi.nlm.ni...
PMID 12809610 View Gene Set 1.514e-09 43 9.488e-08 21 DNA deamination mediates innate immunity to retroviral infection. www.ncbi.nlm.ni...
PMID 12830140 View Gene Set 1.223e-09 42 9.488e-08 21 DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses. www.ncbi.nlm.ni...
PMID 12840737 View Gene Set 1.223e-09 42 9.488e-08 21 Good to CU. www.ncbi.nlm.ni...
PMID 12914693 View Gene Set 1.223e-09 42 9.488e-08 21 Death by deamination: a novel host restriction system for HIV-1. www.ncbi.nlm.ni...
PMID 12920286 View Gene Set 1.223e-09 42 9.488e-08 21 Virology. Weapons of mutational destruction. www.ncbi.nlm.ni...
PMID 12970355 View Gene Set 1.514e-09 43 9.488e-08 21 The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity. www.ncbi.nlm.ni...
PMID 14527406 View Gene Set 1.514e-09 43 9.488e-08 21 HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. www.ncbi.nlm.ni...
PMID 14528300 View Gene Set 1.514e-09 43 9.488e-08 21 The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. www.ncbi.nlm.ni...
PMID 14528301 View Gene Set 1.514e-09 43 9.488e-08 21 HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. www.ncbi.nlm.ni...
PMID 14557625 View Gene Set 1.514e-09 43 9.488e-08 21 The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15) a cellular inhibitor of virus infectivity. www.ncbi.nlm.ni...
PMID 14614829 View Gene Set 1.223e-09 42 9.488e-08 21 The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G. www.ncbi.nlm.ni...
PMID 15189156 View Gene Set 1.374e-09 88 9.488e-08 21 The molecular mechanics of eukaryotic translation. www.ncbi.nlm.ni...
PMID 9811770 View Gene Set 1.223e-09 42 9.488e-08 21 An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein. www.ncbi.nlm.ni...
PMID 9846577 View Gene Set 1.223e-09 42 9.488e-08 21 Evidence for a newly discovered cellular anti-HIV-1 phenotype. www.ncbi.nlm.ni...
PMID 15029244 View Gene Set 1.815e-09 57 1.059e-07 41 Mammalian Cdh1/Fzr mediates its own degradation. www.ncbi.nlm.ni...
PMID 18162579 View Gene Set 1.816e-09 22 1.059e-07 41 Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. www.ncbi.nlm.ni...
PMID 8811196 View Gene Set 1.812e-09 37 1.059e-07 41 Structure and functions of the 20S and 26S proteasomes. www.ncbi.nlm.ni...
PMID 14564014 View Gene Set 1.893e-09 47 1.078e-07 44 Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. www.ncbi.nlm.ni...
PMID 12234937 View Gene Set 2.323e-09 34 1.294e-07 45 Characterization of novel SF3b and 17S U2 snRNP proteins including a human Prp5p homologue and an SF3b DEAD-box protein. www.ncbi.nlm.ni...
PMID 15146077 View Gene Set 4.586e-09 32 2.499e-07 46 The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. www.ncbi.nlm.ni...
PMID 18809582 View Gene Set 7.371e-09 25 3.932e-07 47 Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. www.ncbi.nlm.ni...
PMID 15782174 View Gene Set 2.156e-08 31 1.103e-06 48 Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. www.ncbi.nlm.ni...
PMID 8722009 View Gene Set 2.115e-08 80 1.103e-06 48 Structure and evolution of mammalian ribosomal proteins. www.ncbi.nlm.ni...
PMID 12791985 View Gene Set 2.727e-08 37 1.368e-06 50 Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. www.ncbi.nlm.ni...
PMID 17289661 View Gene Set 2.854e-08 35 1.403e-06 51 Molecular composition of IMP1 ribonucleoprotein granules. www.ncbi.nlm.ni...
PMID 9582194 View Gene Set 3.257e-08 67 1.57e-06 52 A map of 75 human ribosomal protein genes. www.ncbi.nlm.ni...
PMID 20508983 View Gene Set 5.972e-08 102 2.825e-06 53 Centrosome-related genes genetic variation and risk of breast cancer. www.ncbi.nlm.ni...
PMID 9731529 View Gene Set 6.586e-08 24 3.058e-06 54 Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. www.ncbi.nlm.ni...
PMID 15130578 View Gene Set 1.184e-07 22 5.399e-06 55 Why do cells need an assembly machine for RNA-protein complexes? www.ncbi.nlm.ni...
PMID 15231747 View Gene Set 1.22e-07 212 5.462e-06 56 A protein interaction framework for human mRNA degradation. www.ncbi.nlm.ni...
PMID 16916647 View Gene Set 1.983e-07 76 8.721e-06 57 Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. www.ncbi.nlm.ni...
PMID 19710015 View Gene Set 2.359e-07 48 1.02e-05 58 The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor. www.ncbi.nlm.ni...
PMID 15009096 View Gene Set 3.092e-07 39 1.314e-05 59 Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex while BMI-1 is transiently co-localized with the centromeric region in interphase. www.ncbi.nlm.ni...
PMID 12388589 View Gene Set 3.163e-07 17 1.321e-05 60 A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. www.ncbi.nlm.ni...
PMID 12045100 View Gene Set 3.548e-07 18 1.458e-05 61 DNA replication in eukaryotic cells. www.ncbi.nlm.ni...
PMID 15707391 View Gene Set 3.761e-07 23 1.496e-05 62 DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. www.ncbi.nlm.ni...
PMID 17363900 View Gene Set 3.72e-07 14 1.496e-05 62 The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. www.ncbi.nlm.ni...
PMID 19596235 View Gene Set 5.286e-07 85 2.071e-05 64 Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. www.ncbi.nlm.ni...
PMID 11095689 View Gene Set 6.984e-07 17 2.694e-05 65 The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase. www.ncbi.nlm.ni...
PMID 12588972 View Gene Set 1.385e-06 56 5.259e-05 66 Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region. www.ncbi.nlm.ni...
PMID 14567916 View Gene Set 1.507e-06 50 5.638e-05 67 Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. www.ncbi.nlm.ni...
PMID 15226314 View Gene Set 1.81e-06 20 6.672e-05 68 Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. www.ncbi.nlm.ni...
PMID 11101529 View Gene Set 1.912e-06 34 6.946e-05 69 Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. www.ncbi.nlm.ni...
PMID 11205743 View Gene Set 2.07e-06 15 7.415e-05 70 Polo-like kinase interacts with proteasomes and regulates their activity. www.ncbi.nlm.ni...
PMID 17148452 View Gene Set 2.792e-06 87 9.86e-05 71 Characterization of the interactome of the human MutL homologues MLH1 PMS1 and PMS2. www.ncbi.nlm.ni...
PMID 11279123 View Gene Set 2.975e-06 31 0.0001036 72 The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 12614612 View Gene Set 3.052e-06 19 0.0001048 73 Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. www.ncbi.nlm.ni...
PMID 14667819 View Gene Set 3.167e-06 112 0.0001073 74 Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. www.ncbi.nlm.ni...
PMID 18270339 View Gene Set 4.053e-06 57 0.0001355 75 Comprehensive analysis of DNA repair gene variants and risk of meningioma. www.ncbi.nlm.ni...
PMID 10531003 View Gene Set 4.265e-06 15 0.0001395 76 Newly assembled snRNPs associate with coiled bodies before speckles suggesting a nuclear snRNP maturation pathway. www.ncbi.nlm.ni...
PMID 19468067 View Gene Set 4.285e-06 10 0.0001395 76 Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. www.ncbi.nlm.ni...
PMID 15504738 View Gene Set 4.695e-06 19 0.0001509 78 Genes affecting the cell cycle growth maintenance and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. www.ncbi.nlm.ni...
PMID 18063578 View Gene Set 5.516e-06 31 0.000175 79 The layered structure of human mitochondrial DNA nucleoids. www.ncbi.nlm.ni...
PMID 12962325 View Gene Set 6.397e-06 22 0.0002005 80 Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. www.ncbi.nlm.ni...
PMID 14733938 View Gene Set 6.627e-06 13 0.0002051 81 Protein-protein interactions among human 20S proteasome subunits and proteassemblin. www.ncbi.nlm.ni...
PMID 16622420 View Gene Set 7.258e-06 14 0.0002219 82 The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. www.ncbi.nlm.ni...
PMID 19237606 View Gene Set 8.02e-06 84 0.0002422 83 Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. www.ncbi.nlm.ni...
PMID 10436018 View Gene Set 8.658e-06 15 0.0002579 84 The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells. www.ncbi.nlm.ni...
PMID 16622419 View Gene Set 8.743e-06 16 0.0002579 84 The human CENP-A centromeric nucleosome-associated complex. www.ncbi.nlm.ni...
PMID 20496165 View Gene Set 1.052e-05 68 0.0003067 86 Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. www.ncbi.nlm.ni...
PMID 16319397 View Gene Set 1.171e-05 20 0.0003376 87 Characterization of histone H2A and H2B variants and their post-translational modifications by mass spectrometry. www.ncbi.nlm.ni...
PMID 10601333 View Gene Set 1.204e-05 12 0.0003393 88 Gemin3: A novel DEAD box protein that interacts with SMN the spinal muscular atrophy gene product and is a component of gems. www.ncbi.nlm.ni...
PMID 12930902 View Gene Set 1.202e-05 11 0.0003393 88 The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. www.ncbi.nlm.ni...
PMID 11714716 View Gene Set 1.298e-05 13 0.0003616 90 Gemin5 a novel WD repeat protein component of the SMN complex that binds Sm proteins. www.ncbi.nlm.ni...
PMID 12171929 View Gene Set 1.515e-05 31 0.0004175 91 A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. www.ncbi.nlm.ni...
PMID 14966270 View Gene Set 1.734e-05 19 0.0004724 92 Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. www.ncbi.nlm.ni...
PMID 12228227 View Gene Set 1.782e-05 30 0.0004803 93 Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1. www.ncbi.nlm.ni...
PMID 16085932 View Gene Set 1.92e-05 18 0.000512 94 A novel evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. www.ncbi.nlm.ni...
PMID 19270065 View Gene Set 2.254e-05 11 0.0005947 95 MRE11 complex links RECQ5 helicase to sites of DNA damage. www.ncbi.nlm.ni...
PMID 11714285 View Gene Set 3.636e-05 11 0.0008936 96 The appended C-domain of human methionyl-tRNA synthetase has a tRNA-sequestering function. www.ncbi.nlm.ni...
PMID 16055448 View Gene Set 3.636e-05 11 0.0008936 96 The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex. www.ncbi.nlm.ni...
PMID 8052601 View Gene Set 3.636e-05 11 0.0008936 96 Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit. www.ncbi.nlm.ni...
PMID 8078941 View Gene Set 3.636e-05 11 0.0008936 96 Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer. www.ncbi.nlm.ni...
PMID 8188258 View Gene Set 3.636e-05 11 0.0008936 96 The human EPRS locus (formerly the QARS locus): a gene encoding a class I and a class II aminoacyl-tRNA synthetase. www.ncbi.nlm.ni...
PMID 8449960 View Gene Set 3.636e-05 11 0.0008936 96 Expression of human aspartyl-tRNA synthetase in Escherichia coli. Functional analysis of the N-terminal putative amphiphilic helix. www.ncbi.nlm.ni...
PMID 9278442 View Gene Set 3.636e-05 11 0.0008936 96 Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant. www.ncbi.nlm.ni...
PMID 11748230 View Gene Set 3.844e-05 17 0.0009357 103 Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. www.ncbi.nlm.ni...
PMID 18997788 View Gene Set 3.975e-05 10 0.0009582 104 The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction. www.ncbi.nlm.ni...
PMID 15647280 View Gene Set 4.179e-05 17 0.0009977 105 The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. www.ncbi.nlm.ni...
PMID 14743216 View Gene Set 4.273e-05 132 0.001011 106 A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. www.ncbi.nlm.ni...
PMID 16387653 View Gene Set 4.367e-05 42 0.001023 107 ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. www.ncbi.nlm.ni...
PMID 14657027 View Gene Set 4.984e-05 74 0.001157 108 Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. www.ncbi.nlm.ni...
PMID 11080476 View Gene Set 5.13e-05 87 0.00118 109 Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. www.ncbi.nlm.ni...
PMID 11551941 View Gene Set 5.514e-05 26 0.001257 110 The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 10608806 View Gene Set 6.29e-05 25 0.001421 111 Substrate specificities and identification of putative substrates of ATM kinase family members. www.ncbi.nlm.ni...
PMID 11829477 View Gene Set 6.411e-05 13 0.001435 112 Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex. www.ncbi.nlm.ni...
PMID 9562972 View Gene Set 6.975e-05 11 0.001547 113 HIV-1 nuclear import: matrix protein is back on center stage this time together with Vpr. www.ncbi.nlm.ni...
PMID 18377426 View Gene Set 7.658e-05 20 0.001684 114 Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex. www.ncbi.nlm.ni...
PMID 17577209 View Gene Set 7.821e-05 28 0.001705 115 The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing. www.ncbi.nlm.ni...
PMID 16236267 View Gene Set 8.249e-05 77 0.001783 116 Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. www.ncbi.nlm.ni...
PMID 10725331 View Gene Set 8.931e-05 14 0.001914 117 Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. www.ncbi.nlm.ni...
PMID 7811265 View Gene Set 0.0001057 16 0.002245 118 Human proteasome subunits from 2-dimensional gels identified by partial sequencing. www.ncbi.nlm.ni...
PMID 20522537 View Gene Set 0.0001092 73 0.002301 119 Variation within DNA repair pathway genes and risk of multiple sclerosis. www.ncbi.nlm.ni...
PMID 14532270 View Gene Set 0.0001157 12 0.002406 120 A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. www.ncbi.nlm.ni...
PMID 15232106 View Gene Set 0.0001161 30 0.002406 120 Self-assembling protein microarrays. www.ncbi.nlm.ni...
PMID 9878398 View Gene Set 0.0001259 13 0.002588 122 Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. www.ncbi.nlm.ni...
PMID 11416179 View Gene Set 0.000137 12 0.002792 123 All kinesin superfamily protein KIF genes in mouse and human. www.ncbi.nlm.ni...
PMID 12963728 View Gene Set 0.0001383 21 0.002795 124 Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. www.ncbi.nlm.ni...
PMID 19690177 View Gene Set 0.0001746 31 0.003501 125 Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk. www.ncbi.nlm.ni...
PMID 11719186 View Gene Set 0.0001898 17 0.003777 126 AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. www.ncbi.nlm.ni...
PMID 10601273 View Gene Set 0.0002017 21 0.003981 127 Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein whereas export is due to a nuclear export signal sequence in glucokinase. www.ncbi.nlm.ni...
PMID 16716197 View Gene Set 0.0002235 10 0.004377 128 Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. www.ncbi.nlm.ni...
PMID 15960975 View Gene Set 0.0002256 28 0.004383 129 Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. www.ncbi.nlm.ni...
PMID 17220478 View Gene Set 0.0002319 63 0.004472 130 Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells. www.ncbi.nlm.ni...
PMID 11689053 View Gene Set 0.000241 70 0.004613 131 Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA. www.ncbi.nlm.ni...
PMID 15196461 View Gene Set 0.0002452 11 0.00463 132 The highly conserved and multifunctional NuA4 HAT complex. www.ncbi.nlm.ni...
PMID 15456888 View Gene Set 0.0002456 24 0.00463 132 The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. www.ncbi.nlm.ni...
PMID 16713563 View Gene Set 0.0002564 19 0.004797 134 Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. www.ncbi.nlm.ni...
PMID 11713266 View Gene Set 0.0002666 12 0.00495 135 The methylosome a 20S complex containing JBP1 and pICln produces dimethylarginine-modified Sm proteins. www.ncbi.nlm.ni...
PMID 11124703 View Gene Set 0.0002723 18 0.005019 136 Characterization of 16 novel human genes showing high similarity to yeast sequences. www.ncbi.nlm.ni...
PMID 11875025 View Gene Set 0.0002781 41 0.005089 137 The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. www.ncbi.nlm.ni...
PMID 7494303 View Gene Set 0.0003071 12 0.005579 138 Mutational analysis of cell cycle arrest nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr. www.ncbi.nlm.ni...
PMID 11812149 View Gene Set 0.000313 13 0.005605 139 Protein-protein interactions of hCsl4p with other human exosome subunits. www.ncbi.nlm.ni...
PMID 11931757 View Gene Set 0.000312 22 0.005605 139 Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. www.ncbi.nlm.ni...
PMID 18715871 View Gene Set 0.0003205 20 0.005699 141 PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4. www.ncbi.nlm.ni...
PMID 19584272 View Gene Set 0.0003638 11 0.006423 142 Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers. www.ncbi.nlm.ni...
PMID 10064132 View Gene Set 0.0003701 14 0.006488 143 The human H2A and H2B histone gene complement. www.ncbi.nlm.ni...
PMID 11310559 View Gene Set 0.0003786 17 0.006592 144 Identification of nuclear-import and cell-cycle regulatory proteins that bind to prothymosin alpha. www.ncbi.nlm.ni...
PMID 10983978 View Gene Set 0.0004002 10 0.006919 145 Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. www.ncbi.nlm.ni...
PMID 10851237 View Gene Set 0.0004041 11 0.006938 146 Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). www.ncbi.nlm.ni...
PMID 16283522 View Gene Set 0.0004233 18 0.007219 147 Inhibition of core histones acetylation by carcinogenic nickel(II). www.ncbi.nlm.ni...
PMID 16094384 View Gene Set 0.0005142 80 0.00871 148 Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. www.ncbi.nlm.ni...
PMID 20226869 View Gene Set 0.0005567 25 0.009366 149 Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations. www.ncbi.nlm.ni...
PMID 15644312 View Gene Set 0.0005701 10 0.009528 150 Dissection of the mitochondrial import and assembly pathway for human Tom40. www.ncbi.nlm.ni...
PMID 8724849 View Gene Set 0.0005942 41 0.009866 151 Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. www.ncbi.nlm.ni...
PMID 12732143 View Gene Set 0.0006042 14 0.009966 152 The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. www.ncbi.nlm.ni...
PMID 16627869 View Gene Set 0.0006162 17 0.0101 153 Quantitative proteomic analysis of post-translational modifications of human histones. www.ncbi.nlm.ni...
PMID 20516191 View Gene Set 0.0006234 12 0.01015 154 A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins). www.ncbi.nlm.ni...
PMID 11076961 View Gene Set 0.0006425 14 0.01031 155 Characterization of vertebrate cohesin complexes and their regulation in prophase. www.ncbi.nlm.ni...
PMID 11125146 View Gene Set 0.0006396 10 0.01031 155 Inhibition of eukaryotic DNA replication by geminin binding to Cdt1. www.ncbi.nlm.ni...
PMID 12607005 View Gene Set 0.0006497 11 0.01031 155 MDC1 is a mediator of the mammalian DNA damage checkpoint. www.ncbi.nlm.ni...
PMID 18954305 View Gene Set 0.0006496 13 0.01031 155 Structural basis and specificity of human otubain 1-mediated deubiquitination. www.ncbi.nlm.ni...
PMID 19138993 View Gene Set 0.0006542 25 0.01032 159 Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. www.ncbi.nlm.ni...
PMID 11799066 View Gene Set 0.0006826 21 0.01064 160 Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. www.ncbi.nlm.ni...
PMID 12660246 View Gene Set 0.0006911 18 0.01064 160 c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation. www.ncbi.nlm.ni...
PMID 15502821 View Gene Set 0.0006835 12 0.01064 160 A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. www.ncbi.nlm.ni...
PMID 9566873 View Gene Set 0.000692 74 0.01064 160 Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. www.ncbi.nlm.ni...
PMID 12408966 View Gene Set 0.0007121 76 0.01089 164 The human and mouse replication-dependent histone genes. www.ncbi.nlm.ni...
PMID 17525332 View Gene Set 0.0007389 22 0.01123 165 ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. www.ncbi.nlm.ni...
PMID 1574589 View Gene Set 0.0007563 11 0.01142 166 De novo purine nucleotide biosynthesis. www.ncbi.nlm.ni...
PMID 8706699 View Gene Set 0.0007943 35 0.01192 167 Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing and mass spectrometry. www.ncbi.nlm.ni...
PMID 19064565 View Gene Set 0.0008164 13 0.01218 168 Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk. www.ncbi.nlm.ni...
PMID 11401437 View Gene Set 0.0008406 27 0.01247 169 A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders. www.ncbi.nlm.ni...
PMID 15146057 View Gene Set 0.0009067 10 0.01337 170 The entire Nup107-160 complex including three new members is targeted as one entity to kinetochores in mitosis. www.ncbi.nlm.ni...
PMID 11110791 View Gene Set 0.000974 12 0.01428 171 Three novel components of the human exosome. www.ncbi.nlm.ni...
PMID 12419256 View Gene Set 0.001021 12 0.01488 172 Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring. www.ncbi.nlm.ni...
PMID 20193073 View Gene Set 0.001042 52 0.0151 173 Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes. www.ncbi.nlm.ni...
PMID 11799067 View Gene Set 0.001053 10 0.01513 174 E2F integrates cell cycle progression with DNA repair replication and G(2)/M checkpoints. www.ncbi.nlm.ni...
PMID 19209188 View Gene Set 0.001056 13 0.01513 174 Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study. www.ncbi.nlm.ni...
PMID 7821789 View Gene Set 0.001088 59 0.0155 176 Construction of a human full-length cDNA bank. www.ncbi.nlm.ni...
PMID 14983052 View Gene Set 0.001256 391 0.01779 177 The human olfactory receptor gene family. www.ncbi.nlm.ni...
PMID 11914277 View Gene Set 0.001284 38 0.01809 178 miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. www.ncbi.nlm.ni...
PMID 7584028 View Gene Set 0.001298 37 0.01817 179 Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). www.ncbi.nlm.ni...
PMID 11531413 View Gene Set 0.001306 27 0.01819 180 HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25. www.ncbi.nlm.ni...
PMID 15324660 View Gene Set 0.001371 242 0.01899 181 Proteomic functional and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. www.ncbi.nlm.ni...
PMID 12601814 View Gene Set 0.001431 12 0.01964 182 Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis. www.ncbi.nlm.ni...
PMID 1403646 View Gene Set 0.001433 17 0.01964 182 The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC. www.ncbi.nlm.ni...
PMID 12815422 View Gene Set 0.001599 239 0.02179 184 The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. www.ncbi.nlm.ni...
PMID 9472028 View Gene Set 0.001639 12 0.02221 185 SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. www.ncbi.nlm.ni...
PMID 10766737 View Gene Set 0.00168 11 0.02265 186 Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. www.ncbi.nlm.ni...
PMID 15078818 View Gene Set 0.001717 11 0.02289 187 Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo. www.ncbi.nlm.ni...
PMID 16702407 View Gene Set 0.001717 11 0.02289 187 DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A. www.ncbi.nlm.ni...
PMID 12757711 View Gene Set 0.001747 18 0.02318 189 Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. www.ncbi.nlm.ni...
PMID 11564863 View Gene Set 0.001874 23 0.02473 190 Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. www.ncbi.nlm.ni...
PMID 10783165 View Gene Set 0.001902 12 0.02496 191 BASC a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. www.ncbi.nlm.ni...
PMID 11877377 View Gene Set 0.001929 11 0.02518 192 SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. www.ncbi.nlm.ni...
PMID 18082152 View Gene Set 0.002036 11 0.02645 193 Human CpG binding protein interacts with MLL1 MLL2 and hSet1 and regulates Hox gene expression. www.ncbi.nlm.ni...
PMID 11149922 View Gene Set 0.00212 14 0.0274 194 A functional interaction between the survival motor neuron complex and RNA polymerase II. www.ncbi.nlm.ni...
PMID 11073998 View Gene Set 0.002217 15 0.0285 195 TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture. www.ncbi.nlm.ni...
PMID 9439656 View Gene Set 0.002259 55 0.02889 196 The human histone gene cluster at the D6S105 locus. www.ncbi.nlm.ni...
PMID 15883184 View Gene Set 0.002351 31 0.02991 197 Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes. www.ncbi.nlm.ni...
PMID 9822659 View Gene Set 0.002362 11 0.02991 197 Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3. www.ncbi.nlm.ni...
PMID 15149599 View Gene Set 0.002451 12 0.03083 199 Telomere shortening triggers senescence of human cells through a pathway involving ATM p53 and p21(CIP1) but not p16(INK4a). www.ncbi.nlm.ni...
PMID 17041588 View Gene Set 0.00246 19 0.03083 199 CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation. www.ncbi.nlm.ni...

Gene Set Collection: Prosite

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null PS50102 View Gene Set 5.427e-24 229 3.989e-21 1 RRM expasy.org/pros...
Null PS51194 View Gene Set 1.518e-10 113 5.58e-08 2 HELICASE_CTER expasy.org/pros...
Null PS51192 View Gene Set 4.601e-10 112 1.127e-07 3 HELICASE_ATP_BIND_1 expasy.org/pros...
Null PS51195 View Gene Set 6.752e-10 37 1.241e-07 4 Q_MOTIF expasy.org/pros...
Null PS00039 View Gene Set 3.133e-07 27 4.606e-05 5 DEAD_ATP_HELICASE expasy.org/pros...
Null PS00750 View Gene Set 6.954e-06 9 0.0005679 6 TCP1_1 expasy.org/pros...
Null PS00751 View Gene Set 6.954e-06 9 0.0005679 6 TCP1_2 expasy.org/pros...
Null PS00995 View Gene Set 6.954e-06 9 0.0005679 6 TCP1_3 expasy.org/pros...
Null PS50280 View Gene Set 6.277e-06 47 0.0005679 6 SET expasy.org/pros...
Null PS00357 View Gene Set 6.2e-05 19 0.004143 10 HISTONE_H2B expasy.org/pros...
Null PS50082 View Gene Set 5.786e-05 233 0.004143 10 WD_REPEATS_2 expasy.org/pros...
Null PS50294 View Gene Set 7.389e-05 245 0.004526 12 WD_REPEATS_REGION expasy.org/pros...
Null PS50051 View Gene Set 0.000167 8 0.009441 13 MCM_2 expasy.org/pros...
Null PS50174 View Gene Set 0.0002892 25 0.01518 14 G_PATCH expasy.org/pros...
Null PS00046 View Gene Set 0.0005241 21 0.01869 15 HISTONE_H2A expasy.org/pros...
Null PS00388 View Gene Set 0.0006344 8 0.01869 15 PROTEASOME_A_1 expasy.org/pros...
Null PS00674 View Gene Set 0.0004647 29 0.01869 15 AAA expasy.org/pros...
Null PS01358 View Gene Set 0.0004137 25 0.01869 15 ZF_RANBP2_1 expasy.org/pros...
Null PS01359 View Gene Set 0.0005655 72 0.01869 15 ZF_PHD_1 expasy.org/pros...
Null PS50016 View Gene Set 0.0005856 78 0.01869 15 ZF_PHD_2 expasy.org/pros...
Null PS50199 View Gene Set 0.0004137 23 0.01869 15 ZF_RANBP2_2 expasy.org/pros...
Null PS50800 View Gene Set 0.0005435 23 0.01869 15 SAP expasy.org/pros...
Null PS50862 View Gene Set 0.0004847 18 0.01869 15 AA_TRNA_LIGASE_II expasy.org/pros...
Null PS51189 View Gene Set 0.000661 9 0.01869 15 FAT expasy.org/pros...
Null PS51190 View Gene Set 0.000661 9 0.01869 15 FATC expasy.org/pros...
Null PS51214 View Gene Set 0.0005726 10 0.01869 15 IBB expasy.org/pros...
Null PS51273 View Gene Set 0.0007769 6 0.02115 27 GATASE_TYPE_1 expasy.org/pros...
Null PS00178 View Gene Set 0.0008819 15 0.02235 28 AA_TRNA_LIGASE_I expasy.org/pros...
Null PS50030 View Gene Set 0.0008767 42 0.02235 28 UBA expasy.org/pros...
Null PS00469 View Gene Set 0.0009993 6 0.02448 30 NDP_KINASES expasy.org/pros...
Null PS50166 View Gene Set 0.001173 13 0.02782 31 IMPORTIN_B_NT expasy.org/pros...
Null PS00847 View Gene Set 0.001303 6 0.02902 32 MCM_1 expasy.org/pros...
Null PS51151 View Gene Set 0.001302 9 0.02902 32 NAC_AB expasy.org/pros...
Null PS00678 View Gene Set 0.001363 168 0.02948 34 WD_REPEATS_1 expasy.org/pros...
Null PS50833 View Gene Set 0.001627 7 0.03417 35 BRIX expasy.org/pros...
Null PS00854 View Gene Set 0.00174 12 0.03553 36 PROTEASOME_B_1 expasy.org/pros...
Null PS51391 View Gene Set 0.001896 8 0.03767 37 CID expasy.org/pros...

Gene Set Collection: Enzyme

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null EC:3.4.25.1 View Gene Set 1.822e-05 20 0.00144 1 Proteasome endopeptidase complex expasy.org/enzy...
Null EC:3.6.4.13 View Gene Set 9.533e-06 13 0.00144 1 RNA helicase expasy.org/enzy...
Null EC:2.7.7.6 View Gene Set 9.802e-05 17 0.005163 3 DNA-directed RNA polymerase expasy.org/enzy...
Null EC:2.3.1.48 View Gene Set 0.0008902 5 0.03516 4 Histone acetyltransferase expasy.org/enzy...

Gene Set Collection: ppi.BIND

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.RAD51 View Gene Set 5.855e-05 7 0.01107 1 Protein-protein-interaction for RAD51 www.ncbi.nlm.ni...
Null ppi.E2F1 View Gene Set 0.0001333 12 0.0126 2 Protein-protein-interaction for E2F1 www.ncbi.nlm.ni...
Null ppi.155871 View Gene Set 0.0002088 21 0.01316 3 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 0.0009716 8 0.04591 4 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.SNORD3A View Gene Set 0.001242 9 0.04693 5 Protein-protein-interaction for SNORD3A www.ncbi.nlm.ni...

Gene Set Collection: ppi.BioGRID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.155871 View Gene Set 2.552e-36 236 5.861e-33 1 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 4.672e-26 147 5.366e-23 2 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.SRRM1 View Gene Set 2.401e-16 64 1.839e-13 3 Protein-protein-interaction for SRRM1 www.ncbi.nlm.ni...
Null ppi.SRRM2 View Gene Set 2.392e-15 101 1.373e-12 4 Protein-protein-interaction for SRRM2 www.ncbi.nlm.ni...
Null ppi.KHDRBS2 View Gene Set 4.006e-12 46 1.84e-09 5 Protein-protein-interaction for KHDRBS2 www.ncbi.nlm.ni...
Null ppi.GPN1 View Gene Set 2.092e-09 27 8.009e-07 6 Protein-protein-interaction for GPN1 www.ncbi.nlm.ni...
Null ppi.UCHL5 View Gene Set 1.844e-08 33 5.491e-06 7 Protein-protein-interaction for UCHL5 www.ncbi.nlm.ni...
Null ppi.CDT1 View Gene Set 1.912e-08 37 5.491e-06 7 Protein-protein-interaction for CDT1 www.ncbi.nlm.ni...
Null ppi.WBP4 View Gene Set 3.483e-08 35 8.89e-06 9 Protein-protein-interaction for WBP4 www.ncbi.nlm.ni...
Null ppi.72462 View Gene Set 3.951e-08 42 9.075e-06 10 Protein-protein-interaction for 72462 www.ncbi.nlm.ni...
Null ppi.PSMD13 View Gene Set 1.139e-07 20 2.378e-05 11 Protein-protein-interaction for PSMD13 www.ncbi.nlm.ni...
Null ppi.PSMD6 View Gene Set 1.372e-07 21 2.627e-05 12 Protein-protein-interaction for PSMD6 www.ncbi.nlm.ni...
Null ppi.RNU12-2P View Gene Set 1.959e-07 18 3.215e-05 13 Protein-protein-interaction for RNU12-2P www.ncbi.nlm.ni...
Null ppi.RNU11 View Gene Set 1.959e-07 18 3.215e-05 13 Protein-protein-interaction for RNU11 www.ncbi.nlm.ni...
Null ppi.GIYD2 View Gene Set 2.538e-07 32 3.886e-05 15 Protein-protein-interaction for GIYD2 www.ncbi.nlm.ni...
Null ppi.RUVBL2 View Gene Set 2.806e-07 64 4.029e-05 16 Protein-protein-interaction for RUVBL2 www.ncbi.nlm.ni...
Null ppi.SUMO2 View Gene Set 9.463e-07 50 0.0001279 17 Protein-protein-interaction for SUMO2 www.ncbi.nlm.ni...
Null ppi.PSMD14 View Gene Set 1.119e-06 16 0.0001428 18 Protein-protein-interaction for PSMD14 www.ncbi.nlm.ni...
Null ppi.MRE11A View Gene Set 1.453e-06 13 0.0001757 19 Protein-protein-interaction for MRE11A www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 1.731e-06 24 0.0001894 20 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 1.707e-06 43 0.0001894 20 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.RNPS1 View Gene Set 2.001e-06 38 0.0001998 22 Protein-protein-interaction for RNPS1 www.ncbi.nlm.ni...
Null ppi.RPA1 View Gene Set 1.955e-06 23 0.0001998 22 Protein-protein-interaction for RPA1 www.ncbi.nlm.ni...
Null ppi.HIST1H4A View Gene Set 2.687e-06 28 0.0002572 24 Protein-protein-interaction for HIST1H4A www.ncbi.nlm.ni...
Null ppi.EIF3F View Gene Set 4.863e-06 22 0.0004468 25 Protein-protein-interaction for EIF3F www.ncbi.nlm.ni...
Null ppi.TP53BP1 View Gene Set 5.531e-06 13 0.0004886 26 Protein-protein-interaction for TP53BP1 www.ncbi.nlm.ni...
Null ppi.LYAR View Gene Set 5.955e-06 26 0.0005066 27 Protein-protein-interaction for LYAR www.ncbi.nlm.ni...
Null ppi.PAXIP1 View Gene Set 7.071e-06 18 0.0005801 28 Protein-protein-interaction for PAXIP1 www.ncbi.nlm.ni...
Null ppi.AURKA View Gene Set 8.296e-06 9 0.0006571 29 Protein-protein-interaction for AURKA www.ncbi.nlm.ni...
Null ppi.DDX20 View Gene Set 1.065e-05 17 0.0007642 30 Protein-protein-interaction for DDX20 www.ncbi.nlm.ni...
Null ppi.RAD51 View Gene Set 1.026e-05 12 0.0007642 30 Protein-protein-interaction for RAD51 www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 1.058e-05 14 0.0007642 30 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.TERF2 View Gene Set 1.697e-05 9 0.001181 33 Protein-protein-interaction for TERF2 www.ncbi.nlm.ni...
Null ppi.C20orf20 View Gene Set 1.996e-05 15 0.001274 34 Protein-protein-interaction for C20orf20 www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 1.934e-05 53 0.001274 34 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 1.966e-05 168 0.001274 34 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.GTF3C3 View Gene Set 2.156e-05 11 0.001339 37 Protein-protein-interaction for GTF3C3 www.ncbi.nlm.ni...
Null ppi.RRP1B View Gene Set 2.559e-05 21 0.001547 38 Protein-protein-interaction for RRP1B www.ncbi.nlm.ni...
Null ppi.USP39 View Gene Set 2.743e-05 15 0.001615 39 Protein-protein-interaction for USP39 www.ncbi.nlm.ni...
Null ppi.KAT2A View Gene Set 2.84e-05 12 0.001631 40 Protein-protein-interaction for KAT2A www.ncbi.nlm.ni...
Null ppi.USP14 View Gene Set 3.181e-05 22 0.001782 41 Protein-protein-interaction for USP14 www.ncbi.nlm.ni...
Null ppi.ORC6L View Gene Set 5.168e-05 11 0.002808 42 Protein-protein-interaction for ORC6L www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 5.257e-05 9 0.002808 42 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.WWOX View Gene Set 5.446e-05 19 0.002843 44 Protein-protein-interaction for WWOX www.ncbi.nlm.ni...
Null ppi.MCPH1 View Gene Set 6.311e-05 17 0.003221 45 Protein-protein-interaction for MCPH1 www.ncbi.nlm.ni...
Null ppi.TADA3 View Gene Set 6.909e-05 21 0.00345 46 Protein-protein-interaction for TADA3 www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 7.818e-05 40 0.003821 47 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.EIF3H View Gene Set 8.072e-05 16 0.003863 48 Protein-protein-interaction for EIF3H www.ncbi.nlm.ni...
Null ppi.MLH1 View Gene Set 9.287e-05 9 0.004353 49 Protein-protein-interaction for MLH1 www.ncbi.nlm.ni...
Null ppi.PAAF1 View Gene Set 9.575e-05 20 0.004399 50 Protein-protein-interaction for PAAF1 www.ncbi.nlm.ni...
Null ppi.RAD50 View Gene Set 0.0001129 20 0.005085 51 Protein-protein-interaction for RAD50 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 0.0001152 12 0.00509 52 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.USP42 View Gene Set 0.0001186 24 0.00514 53 Protein-protein-interaction for USP42 www.ncbi.nlm.ni...
Null ppi.SUPT3H View Gene Set 0.000121 14 0.005146 54 Protein-protein-interaction for SUPT3H www.ncbi.nlm.ni...
Null ppi.PSMD10 View Gene Set 0.0001234 14 0.005152 55 Protein-protein-interaction for PSMD10 www.ncbi.nlm.ni...
Null ppi.RPAP1 View Gene Set 0.0001354 24 0.005553 56 Protein-protein-interaction for RPAP1 www.ncbi.nlm.ni...
Null ppi.RUVBL1 View Gene Set 0.0001401 38 0.005644 57 Protein-protein-interaction for RUVBL1 www.ncbi.nlm.ni...
Null ppi.RPAP3 View Gene Set 0.0001432 29 0.005671 58 Protein-protein-interaction for RPAP3 www.ncbi.nlm.ni...
Null ppi.NUP62 View Gene Set 0.00015 15 0.005842 59 Protein-protein-interaction for NUP62 www.ncbi.nlm.ni...
Null ppi.CHTF18 View Gene Set 0.0001598 13 0.006116 60 Protein-protein-interaction for CHTF18 www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 0.0001802 19 0.006786 61 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.HIST4H4 View Gene Set 0.0001863 21 0.006794 62 Protein-protein-interaction for HIST4H4 www.ncbi.nlm.ni...
Null ppi.PSMD7 View Gene Set 0.0001851 12 0.006794 62 Protein-protein-interaction for PSMD7 www.ncbi.nlm.ni...
Null ppi.POLR3C View Gene Set 0.0001995 10 0.007051 64 Protein-protein-interaction for POLR3C www.ncbi.nlm.ni...
Null ppi.TAF10 View Gene Set 0.0001971 27 0.007051 64 Protein-protein-interaction for TAF10 www.ncbi.nlm.ni...
Null ppi.BRF2 View Gene Set 0.0002092 23 0.007282 66 Protein-protein-interaction for BRF2 www.ncbi.nlm.ni...
Null ppi.MCM8 View Gene Set 0.0002202 6 0.007548 67 Protein-protein-interaction for MCM8 www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 0.000246 9 0.008193 68 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.NBN View Gene Set 0.0002461 13 0.008193 68 Protein-protein-interaction for NBN www.ncbi.nlm.ni...
Null ppi.THAP1 View Gene Set 0.0002713 11 0.008901 70 Protein-protein-interaction for THAP1 www.ncbi.nlm.ni...
Null ppi.CTCF View Gene Set 0.0002787 6 0.009015 71 Protein-protein-interaction for CTCF www.ncbi.nlm.ni...
Null ppi.SF3B3 View Gene Set 0.0002876 16 0.009175 72 Protein-protein-interaction for SF3B3 www.ncbi.nlm.ni...
Null ppi.ATXN7 View Gene Set 0.0002984 10 0.00939 73 Protein-protein-interaction for ATXN7 www.ncbi.nlm.ni...
Null ppi.SRPK2 View Gene Set 0.0003221 7 0.009961 74 Protein-protein-interaction for SRPK2 www.ncbi.nlm.ni...
Null ppi.USF2 View Gene Set 0.0003252 13 0.009961 74 Protein-protein-interaction for USF2 www.ncbi.nlm.ni...
Null ppi.HIST3H3 View Gene Set 0.0003452 16 0.01043 76 Protein-protein-interaction for HIST3H3 www.ncbi.nlm.ni...
Null ppi.PRPF19 View Gene Set 0.0003517 9 0.01047 77 Protein-protein-interaction for PRPF19 www.ncbi.nlm.ni...
Null ppi.MDC1 View Gene Set 0.0003554 20 0.01047 77 Protein-protein-interaction for MDC1 www.ncbi.nlm.ni...
Null ppi.SF3A2 View Gene Set 0.0003806 16 0.01107 79 Protein-protein-interaction for SF3A2 www.ncbi.nlm.ni...
Null ppi.RAD17 View Gene Set 0.0003984 13 0.01119 80 Protein-protein-interaction for RAD17 www.ncbi.nlm.ni...
Null ppi.WDR77 View Gene Set 0.0003995 15 0.01119 80 Protein-protein-interaction for WDR77 www.ncbi.nlm.ni...
Null ppi.KAT2B View Gene Set 0.0003935 71 0.01119 80 Protein-protein-interaction for KAT2B www.ncbi.nlm.ni...
Null ppi.GEMIN5 View Gene Set 0.0004223 11 0.01169 83 Protein-protein-interaction for GEMIN5 www.ncbi.nlm.ni...
Null ppi.DPY30 View Gene Set 0.0004383 9 0.01199 84 Protein-protein-interaction for DPY30 www.ncbi.nlm.ni...
Null ppi.KLF13 View Gene Set 0.0004557 9 0.01232 85 Protein-protein-interaction for KLF13 www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 0.0005031 15 0.01326 86 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.YY1 View Gene Set 0.0005047 34 0.01326 86 Protein-protein-interaction for YY1 www.ncbi.nlm.ni...
Null ppi.HIST2H2AC View Gene Set 0.0005079 13 0.01326 86 Protein-protein-interaction for HIST2H2AC www.ncbi.nlm.ni...
Null ppi.PDS5A View Gene Set 0.0005347 6 0.01355 89 Protein-protein-interaction for PDS5A www.ncbi.nlm.ni...
Null ppi.MDM4 View Gene Set 0.0005329 10 0.01355 89 Protein-protein-interaction for MDM4 www.ncbi.nlm.ni...
Null ppi.DDX56 View Gene Set 0.0005369 20 0.01355 89 Protein-protein-interaction for DDX56 www.ncbi.nlm.ni...
Null ppi.FEN1 View Gene Set 0.0006124 11 0.01481 92 Protein-protein-interaction for FEN1 www.ncbi.nlm.ni...
Null ppi.PRMT1 View Gene Set 0.0006099 15 0.01481 92 Protein-protein-interaction for PRMT1 www.ncbi.nlm.ni...
Null ppi.C16orf53 View Gene Set 0.0006123 9 0.01481 92 Protein-protein-interaction for C16orf53 www.ncbi.nlm.ni...
Null ppi.MUS81 View Gene Set 0.000596 6 0.01481 92 Protein-protein-interaction for MUS81 www.ncbi.nlm.ni...
Null ppi.TTI1 View Gene Set 0.0006693 8 0.01601 96 Protein-protein-interaction for TTI1 www.ncbi.nlm.ni...
Null ppi.TAF1D View Gene Set 0.0006885 21 0.0163 97 Protein-protein-interaction for TAF1D www.ncbi.nlm.ni...
Null ppi.RBMX View Gene Set 0.000724 15 0.01697 98 Protein-protein-interaction for RBMX www.ncbi.nlm.ni...
Null ppi.PPP4R2 View Gene Set 0.000751 7 0.01725 99 Protein-protein-interaction for PPP4R2 www.ncbi.nlm.ni...
Null ppi.PCBD1 View Gene Set 0.0007451 6 0.01725 99 Protein-protein-interaction for PCBD1 www.ncbi.nlm.ni...
Null ppi.KPNA2 View Gene Set 0.0008057 14 0.0178 101 Protein-protein-interaction for KPNA2 www.ncbi.nlm.ni...
Null ppi.POLR2A View Gene Set 0.0007856 25 0.0178 101 Protein-protein-interaction for POLR2A www.ncbi.nlm.ni...
Null ppi.850620 View Gene Set 0.0008061 20 0.0178 101 Protein-protein-interaction for 850620 www.ncbi.nlm.ni...
Null ppi.EIF3A View Gene Set 0.0007953 12 0.0178 101 Protein-protein-interaction for EIF3A www.ncbi.nlm.ni...
Null ppi.NUP43 View Gene Set 0.0008555 6 0.0187 105 Protein-protein-interaction for NUP43 www.ncbi.nlm.ni...
Null ppi.POLR1E View Gene Set 0.0008631 11 0.0187 105 Protein-protein-interaction for POLR1E www.ncbi.nlm.ni...
Null ppi.HIST1H3A View Gene Set 0.0008725 30 0.01873 107 Protein-protein-interaction for HIST1H3A www.ncbi.nlm.ni...
Null ppi.MGMT View Gene Set 0.0008978 28 0.01909 108 Protein-protein-interaction for MGMT www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 0.0009057 11 0.01909 108 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.PRKDC View Gene Set 0.0009474 38 0.01978 110 Protein-protein-interaction for PRKDC www.ncbi.nlm.ni...
Null ppi.USP19 View Gene Set 0.001059 17 0.02192 111 Protein-protein-interaction for USP19 www.ncbi.nlm.ni...
Null ppi.MED26 View Gene Set 0.001075 22 0.02205 112 Protein-protein-interaction for MED26 www.ncbi.nlm.ni...
Null ppi.SMAD6 View Gene Set 0.001088 6 0.02212 113 Protein-protein-interaction for SMAD6 www.ncbi.nlm.ni...
Null ppi.CDCA5 View Gene Set 0.001142 6 0.023 114 Protein-protein-interaction for CDCA5 www.ncbi.nlm.ni...
Null ppi.COPS6 View Gene Set 0.001198 65 0.02373 115 Protein-protein-interaction for COPS6 www.ncbi.nlm.ni...
Null ppi.GAR1 View Gene Set 0.001198 9 0.02373 115 Protein-protein-interaction for GAR1 www.ncbi.nlm.ni...
Null ppi.MYST1 View Gene Set 0.001219 14 0.02394 117 Protein-protein-interaction for MYST1 www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 0.00125 10 0.02414 118 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.NEDD4 View Gene Set 0.001244 18 0.02414 118 Protein-protein-interaction for NEDD4 www.ncbi.nlm.ni...
Null ppi.TOP1 View Gene Set 0.001275 10 0.0244 120 Protein-protein-interaction for TOP1 www.ncbi.nlm.ni...
Null ppi.FANCD2 View Gene Set 0.001305 6 0.02477 121 Protein-protein-interaction for FANCD2 www.ncbi.nlm.ni...
Null ppi.PPARGC1A View Gene Set 0.001396 33 0.02628 122 Protein-protein-interaction for PPARGC1A www.ncbi.nlm.ni...
Null ppi.CSNK2A1 View Gene Set 0.001413 12 0.02639 123 Protein-protein-interaction for CSNK2A1 www.ncbi.nlm.ni...
Null ppi.POLR3E View Gene Set 0.00146 6 0.02704 124 Protein-protein-interaction for POLR3E www.ncbi.nlm.ni...
Null ppi.ING3 View Gene Set 0.001486 10 0.02731 125 Protein-protein-interaction for ING3 www.ncbi.nlm.ni...
Null ppi.RNMTL1 View Gene Set 0.001529 8 0.02787 126 Protein-protein-interaction for RNMTL1 www.ncbi.nlm.ni...
Null ppi.EP400 View Gene Set 0.001572 10 0.02843 127 Protein-protein-interaction for EP400 www.ncbi.nlm.ni...
Null ppi.CD2BP2 View Gene Set 0.001599 13 0.02869 128 Protein-protein-interaction for CD2BP2 www.ncbi.nlm.ni...
Null ppi.WDR48 View Gene Set 0.001685 52 0.02954 129 Protein-protein-interaction for WDR48 www.ncbi.nlm.ni...
Null ppi.TRRAP View Gene Set 0.001662 21 0.02954 129 Protein-protein-interaction for TRRAP www.ncbi.nlm.ni...
Null ppi.CDC45 View Gene Set 0.001679 9 0.02954 129 Protein-protein-interaction for CDC45 www.ncbi.nlm.ni...
Null ppi.PSTPIP1 View Gene Set 0.001716 25 0.02986 132 Protein-protein-interaction for PSTPIP1 www.ncbi.nlm.ni...
Null ppi.MYSM1 View Gene Set 0.001749 13 0.03019 133 Protein-protein-interaction for MYSM1 www.ncbi.nlm.ni...
Null ppi.WDR33 View Gene Set 0.001761 13 0.03019 133 Protein-protein-interaction for WDR33 www.ncbi.nlm.ni...
Null ppi.HIST2H3C View Gene Set 0.001801 26 0.03064 135 Protein-protein-interaction for HIST2H3C www.ncbi.nlm.ni...
Null ppi.PHF17 View Gene Set 0.001835 7 0.03099 136 Protein-protein-interaction for PHF17 www.ncbi.nlm.ni...
Null ppi.TAF12 View Gene Set 0.001876 10 0.03145 137 Protein-protein-interaction for TAF12 www.ncbi.nlm.ni...
Null ppi.TOR1AIP2 View Gene Set 0.001922 6 0.0318 138 Protein-protein-interaction for TOR1AIP2 www.ncbi.nlm.ni...
Null ppi.SF3B1 View Gene Set 0.001924 24 0.0318 138 Protein-protein-interaction for SF3B1 www.ncbi.nlm.ni...
Null ppi.CDC7 View Gene Set 0.001945 7 0.03191 140 Protein-protein-interaction for CDC7 www.ncbi.nlm.ni...
Null ppi.LSM3 View Gene Set 0.001963 9 0.03198 141 Protein-protein-interaction for LSM3 www.ncbi.nlm.ni...
Null ppi.UPF3A View Gene Set 0.001999 15 0.03222 142 Protein-protein-interaction for UPF3A www.ncbi.nlm.ni...
Null ppi.MIS12 View Gene Set 0.002006 9 0.03222 142 Protein-protein-interaction for MIS12 www.ncbi.nlm.ni...
Null ppi.SNRPF View Gene Set 0.002041 6 0.03256 144 Protein-protein-interaction for SNRPF www.ncbi.nlm.ni...
Null ppi.CDC16 View Gene Set 0.002074 10 0.03285 145 Protein-protein-interaction for CDC16 www.ncbi.nlm.ni...
Null ppi.USP36 View Gene Set 0.002098 17 0.03301 146 Protein-protein-interaction for USP36 www.ncbi.nlm.ni...
Null ppi.CPSF7 View Gene Set 0.002132 11 0.03332 147 Protein-protein-interaction for CPSF7 www.ncbi.nlm.ni...
Null ppi.EEF1G View Gene Set 0.002282 9 0.03471 148 Protein-protein-interaction for EEF1G www.ncbi.nlm.ni...
Null ppi.UPF2 View Gene Set 0.002261 12 0.03471 148 Protein-protein-interaction for UPF2 www.ncbi.nlm.ni...
Null ppi.MED30 View Gene Set 0.002281 26 0.03471 148 Protein-protein-interaction for MED30 www.ncbi.nlm.ni...
Null ppi.NMI View Gene Set 0.002246 12 0.03471 148 Protein-protein-interaction for NMI www.ncbi.nlm.ni...
Null ppi.FANCA View Gene Set 0.002336 14 0.03513 152 Protein-protein-interaction for FANCA www.ncbi.nlm.ni...
Null ppi.UBE2I View Gene Set 0.00234 62 0.03513 152 Protein-protein-interaction for UBE2I www.ncbi.nlm.ni...
Null ppi.COPS8 View Gene Set 0.002389 8 0.03543 154 Protein-protein-interaction for COPS8 www.ncbi.nlm.ni...
Null ppi.POLR3H View Gene Set 0.002391 14 0.03543 154 Protein-protein-interaction for POLR3H www.ncbi.nlm.ni...
Null ppi.PTCD3 View Gene Set 0.002443 6 0.03597 156 Protein-protein-interaction for PTCD3 www.ncbi.nlm.ni...
Null ppi.XPO1 View Gene Set 0.002481 24 0.03629 157 Protein-protein-interaction for XPO1 www.ncbi.nlm.ni...
Null ppi.GIGYF2 View Gene Set 0.00252 17 0.03649 158 Protein-protein-interaction for GIGYF2 www.ncbi.nlm.ni...
Null ppi.PPP2R2A View Gene Set 0.002535 9 0.03649 158 Protein-protein-interaction for PPP2R2A www.ncbi.nlm.ni...
Null ppi.OTUB1 View Gene Set 0.002573 18 0.03649 158 Protein-protein-interaction for OTUB1 www.ncbi.nlm.ni...
Null ppi.DMAP1 View Gene Set 0.002566 13 0.03649 158 Protein-protein-interaction for DMAP1 www.ncbi.nlm.ni...
Null ppi.MBD3L1 View Gene Set 0.002574 11 0.03649 158 Protein-protein-interaction for MBD3L1 www.ncbi.nlm.ni...
Null ppi.KAT5 View Gene Set 0.002602 51 0.03666 163 Protein-protein-interaction for KAT5 www.ncbi.nlm.ni...
Null ppi.MED9 View Gene Set 0.002618 31 0.03666 163 Protein-protein-interaction for MED9 www.ncbi.nlm.ni...
Null ppi.DEK View Gene Set 0.002702 8 0.03762 165 Protein-protein-interaction for DEK www.ncbi.nlm.ni...
Null ppi.GRINL1A View Gene Set 0.002763 17 0.03823 166 Protein-protein-interaction for GRINL1A www.ncbi.nlm.ni...
Null ppi.NUP98 View Gene Set 0.002883 10 0.03903 167 Protein-protein-interaction for NUP98 www.ncbi.nlm.ni...
Null ppi.NAA38 View Gene Set 0.002883 21 0.03903 167 Protein-protein-interaction for NAA38 www.ncbi.nlm.ni...
Null ppi.XPO5 View Gene Set 0.002873 11 0.03903 167 Protein-protein-interaction for XPO5 www.ncbi.nlm.ni...
Null ppi.TTR View Gene Set 0.002889 9 0.03903 167 Protein-protein-interaction for TTR www.ncbi.nlm.ni...
Null ppi.TERF1 View Gene Set 0.002945 15 0.03956 171 Protein-protein-interaction for TERF1 www.ncbi.nlm.ni...
Null ppi.POLR2C View Gene Set 0.002968 7 0.03963 172 Protein-protein-interaction for POLR2C www.ncbi.nlm.ni...
Null ppi.PUF60 View Gene Set 0.003011 31 0.03979 173 Protein-protein-interaction for PUF60 www.ncbi.nlm.ni...
Null ppi.EIF3B View Gene Set 0.003014 10 0.03979 173 Protein-protein-interaction for EIF3B www.ncbi.nlm.ni...
Null ppi.HIST2H2BE View Gene Set 0.003033 17 0.0398 175 Protein-protein-interaction for HIST2H2BE www.ncbi.nlm.ni...
Null ppi.HNRNPUL1 View Gene Set 0.003062 9 0.03997 176 Protein-protein-interaction for HNRNPUL1 www.ncbi.nlm.ni...
Null ppi.KPNA3 View Gene Set 0.003089 6 0.04009 177 Protein-protein-interaction for KPNA3 www.ncbi.nlm.ni...
Null ppi.CXXC1 View Gene Set 0.003169 13 0.04089 178 Protein-protein-interaction for CXXC1 www.ncbi.nlm.ni...
Null ppi.HUWE1 View Gene Set 0.003275 8 0.04203 179 Protein-protein-interaction for HUWE1 www.ncbi.nlm.ni...
Null ppi.HNRNPL View Gene Set 0.003422 8 0.04272 180 Protein-protein-interaction for HNRNPL www.ncbi.nlm.ni...
Null ppi.CLSPN View Gene Set 0.003375 17 0.04272 180 Protein-protein-interaction for CLSPN www.ncbi.nlm.ni...
Null ppi.VIM View Gene Set 0.003422 36 0.04272 180 Protein-protein-interaction for VIM www.ncbi.nlm.ni...
Null ppi.ING5 View Gene Set 0.003385 20 0.04272 180 Protein-protein-interaction for ING5 www.ncbi.nlm.ni...
Null ppi.MED17 View Gene Set 0.003391 15 0.04272 180 Protein-protein-interaction for MED17 www.ncbi.nlm.ni...
Null ppi.LSM7 View Gene Set 0.003512 13 0.04361 185 Protein-protein-interaction for LSM7 www.ncbi.nlm.ni...
Null ppi.SUPT16H View Gene Set 0.003575 11 0.04415 186 Protein-protein-interaction for SUPT16H www.ncbi.nlm.ni...
Null ppi.C19orf40 View Gene Set 0.00364 6 0.04471 187 Protein-protein-interaction for C19orf40 www.ncbi.nlm.ni...
Null ppi.HIST2H3A View Gene Set 0.003749 15 0.04581 188 Protein-protein-interaction for HIST2H3A www.ncbi.nlm.ni...
Null ppi.MSH2 View Gene Set 0.003891 16 0.04728 189 Protein-protein-interaction for MSH2 www.ncbi.nlm.ni...
Null ppi.PINX1 View Gene Set 0.003972 19 0.04802 190 Protein-protein-interaction for PINX1 www.ncbi.nlm.ni...
Null ppi.ZRANB2 View Gene Set 0.00402 6 0.04834 191 Protein-protein-interaction for ZRANB2 www.ncbi.nlm.ni...
Null ppi.FAF2 View Gene Set 0.004064 7 0.0485 192 Protein-protein-interaction for FAF2 www.ncbi.nlm.ni...
Null ppi.DSTYK View Gene Set 0.004096 11 0.0485 192 Protein-protein-interaction for DSTYK www.ncbi.nlm.ni...
Null ppi.HNF1A View Gene Set 0.00408 12 0.0485 192 Protein-protein-interaction for HNF1A www.ncbi.nlm.ni...
Null ppi.MED24 View Gene Set 0.004121 20 0.04854 195 Protein-protein-interaction for MED24 www.ncbi.nlm.ni...
Null ppi.ORC1L View Gene Set 0.00423 9 0.04957 196 Protein-protein-interaction for ORC1L www.ncbi.nlm.ni...

Gene Set Collection: ppi.HPRD

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.SFRS12 View Gene Set 2.145e-13 49 5.092e-10 1 Protein-protein-interaction for SFRS12 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 3.761e-07 166 0.0004464 2 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.SNIP1 View Gene Set 1.04e-05 27 0.008229 3 Protein-protein-interaction for SNIP1 www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 1.697e-05 13 0.01007 4 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.NUP62 View Gene Set 3.336e-05 19 0.01346 5 Protein-protein-interaction for NUP62 www.ncbi.nlm.ni...
Null ppi.NUP98 View Gene Set 3.403e-05 8 0.01346 5 Protein-protein-interaction for NUP98 www.ncbi.nlm.ni...
Null ppi.SUMO4 View Gene Set 7.019e-05 76 0.01515 7 Protein-protein-interaction for SUMO4 www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 6.836e-05 55 0.01515 7 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.DCLRE1C View Gene Set 4.772e-05 8 0.01515 7 Protein-protein-interaction for DCLRE1C www.ncbi.nlm.ni...
Null ppi.ZMYM2 View Gene Set 6.265e-05 12 0.01515 7 Protein-protein-interaction for ZMYM2 www.ncbi.nlm.ni...
Null ppi.MDC1 View Gene Set 5.78e-05 11 0.01515 7 Protein-protein-interaction for MDC1 www.ncbi.nlm.ni...
Null ppi.PLK1 View Gene Set 8.531e-05 14 0.01688 12 Protein-protein-interaction for PLK1 www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 0.0001194 14 0.02024 13 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.RAN View Gene Set 0.0001164 14 0.02024 13 Protein-protein-interaction for RAN www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 0.0001603 17 0.02537 15 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.PABPC1 View Gene Set 0.0001851 21 0.0268 16 Protein-protein-interaction for PABPC1 www.ncbi.nlm.ni...
Null ppi.CDC16 View Gene Set 0.0001919 10 0.0268 16 Protein-protein-interaction for CDC16 www.ncbi.nlm.ni...
Null ppi.ORC6L View Gene Set 0.0002055 10 0.0271 18 Protein-protein-interaction for ORC6L www.ncbi.nlm.ni...
Null ppi.PSMA7 View Gene Set 0.0002234 10 0.02791 19 Protein-protein-interaction for PSMA7 www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 0.0002736 8 0.03093 20 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.SIP1 View Gene Set 0.0002715 13 0.03093 20 Protein-protein-interaction for SIP1 www.ncbi.nlm.ni...
Null ppi.TACC2 View Gene Set 0.0003055 10 0.03235 22 Protein-protein-interaction for TACC2 www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 0.0003134 18 0.03235 22 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.YBX1 View Gene Set 0.0003426 10 0.03292 24 Protein-protein-interaction for YBX1 www.ncbi.nlm.ni...
Null ppi.XPO5 View Gene Set 0.0003699 9 0.03292 24 Protein-protein-interaction for XPO5 www.ncbi.nlm.ni...
Null ppi.SRPK1 View Gene Set 0.0003745 12 0.03292 24 Protein-protein-interaction for SRPK1 www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 0.0003606 10 0.03292 24 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.NCBP1 View Gene Set 0.0004398 7 0.03632 28 Protein-protein-interaction for NCBP1 www.ncbi.nlm.ni...
Null ppi.TTR View Gene Set 0.0004436 13 0.03632 28 Protein-protein-interaction for TTR www.ncbi.nlm.ni...
Null ppi.NCBP2 View Gene Set 0.0004875 6 0.03858 30 Protein-protein-interaction for NCBP2 www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 0.0005243 27 0.04015 31 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.NOL12 View Gene Set 0.0005501 7 0.04081 32 Protein-protein-interaction for NOL12 www.ncbi.nlm.ni...
Null ppi.MYC View Gene Set 0.0005942 28 0.04149 33 Protein-protein-interaction for MYC www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 0.0005839 13 0.04149 33 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.UPF2 View Gene Set 0.000644 16 0.04247 35 Protein-protein-interaction for UPF2 www.ncbi.nlm.ni...
Null ppi.RAD17 View Gene Set 0.0006325 9 0.04247 35 Protein-protein-interaction for RAD17 www.ncbi.nlm.ni...
Null ppi.PSMB7 View Gene Set 0.0006668 6 0.04278 37 Protein-protein-interaction for PSMB7 www.ncbi.nlm.ni...
Null ppi.PSMB5 View Gene Set 0.0007332 8 0.04463 38 Protein-protein-interaction for PSMB5 www.ncbi.nlm.ni...
Null ppi.TAF1A View Gene Set 0.0007163 7 0.04463 38 Protein-protein-interaction for TAF1A www.ncbi.nlm.ni...
Null ppi.LEF1 View Gene Set 0.0007886 18 0.0468 40 Protein-protein-interaction for LEF1 www.ncbi.nlm.ni...
Null ppi.NAA38 View Gene Set 0.0008485 20 0.0473 41 Protein-protein-interaction for NAA38 www.ncbi.nlm.ni...
Null ppi.CDC45 View Gene Set 0.0008568 9 0.0473 41 Protein-protein-interaction for CDC45 www.ncbi.nlm.ni...
Null ppi.EIF2S2 View Gene Set 0.0008459 17 0.0473 41 Protein-protein-interaction for EIF2S2 www.ncbi.nlm.ni...

Gene Set Collection: ppi.anyDB

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.155871 View Gene Set 1.611e-38 251 5.788e-35 1 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 4.672e-26 147 8.396e-23 2 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.SRRM1 View Gene Set 2.667e-15 66 2.396e-12 3 Protein-protein-interaction for SRRM1 www.ncbi.nlm.ni...
Null ppi.SRRM2 View Gene Set 2.392e-15 101 2.396e-12 3 Protein-protein-interaction for SRRM2 www.ncbi.nlm.ni...
Null ppi.SFRS12 View Gene Set 8.584e-14 50 6.17e-11 5 Protein-protein-interaction for SFRS12 www.ncbi.nlm.ni...
Null ppi.KHDRBS2 View Gene Set 8.393e-12 48 5.027e-09 6 Protein-protein-interaction for KHDRBS2 www.ncbi.nlm.ni...
Null ppi.GPN1 View Gene Set 2.092e-09 27 9.769e-07 7 Protein-protein-interaction for GPN1 www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 2.174e-09 96 9.769e-07 7 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.UCHL5 View Gene Set 1.254e-08 34 5.009e-06 9 Protein-protein-interaction for UCHL5 www.ncbi.nlm.ni...
Null ppi.WBP4 View Gene Set 3.483e-08 35 1.207e-05 10 Protein-protein-interaction for WBP4 www.ncbi.nlm.ni...
Null ppi.72462 View Gene Set 3.951e-08 42 1.207e-05 10 Protein-protein-interaction for 72462 www.ncbi.nlm.ni...
Null ppi.CDT1 View Gene Set 4.03e-08 42 1.207e-05 10 Protein-protein-interaction for CDT1 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 4.467e-08 220 1.235e-05 13 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.PSMD13 View Gene Set 1.139e-07 20 2.923e-05 14 Protein-protein-interaction for PSMD13 www.ncbi.nlm.ni...
Null ppi.RNU12-2P View Gene Set 1.959e-07 18 4.401e-05 15 Protein-protein-interaction for RNU12-2P www.ncbi.nlm.ni...
Null ppi.RNU11 View Gene Set 1.959e-07 18 4.401e-05 15 Protein-protein-interaction for RNU11 www.ncbi.nlm.ni...
Null ppi.GIYD2 View Gene Set 2.538e-07 32 5.365e-05 17 Protein-protein-interaction for GIYD2 www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 3.613e-07 16 7.214e-05 18 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.NUP62 View Gene Set 7.762e-07 25 0.0001468 19 Protein-protein-interaction for NUP62 www.ncbi.nlm.ni...
Null ppi.PSMD14 View Gene Set 1.119e-06 16 0.0002011 20 Protein-protein-interaction for PSMD14 www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 1.707e-06 43 0.0002922 21 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 1.923e-06 25 0.0003141 22 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.PSMD6 View Gene Set 2.07e-06 23 0.0003235 23 Protein-protein-interaction for PSMD6 www.ncbi.nlm.ni...
Null ppi.ORC6L View Gene Set 2.766e-06 15 0.0003977 24 Protein-protein-interaction for ORC6L www.ncbi.nlm.ni...
Null ppi.HIST1H4A View Gene Set 2.696e-06 31 0.0003977 24 Protein-protein-interaction for HIST1H4A www.ncbi.nlm.ni...
Null ppi.KAT2A View Gene Set 3.698e-06 14 0.0005112 26 Protein-protein-interaction for KAT2A www.ncbi.nlm.ni...
Null ppi.RPA1 View Gene Set 4.526e-06 24 0.0006024 27 Protein-protein-interaction for RPA1 www.ncbi.nlm.ni...
Null ppi.RUVBL2 View Gene Set 5.071e-06 72 0.0006509 28 Protein-protein-interaction for RUVBL2 www.ncbi.nlm.ni...
Null ppi.LYAR View Gene Set 5.955e-06 26 0.0007379 29 Protein-protein-interaction for LYAR www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 8.365e-06 52 0.001002 30 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 9.49e-06 17 0.0011 31 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 1.241e-05 21 0.001393 32 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.MRE11A View Gene Set 1.555e-05 16 0.001693 33 Protein-protein-interaction for MRE11A www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 1.654e-05 33 0.001749 34 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.SNIP1 View Gene Set 1.858e-05 28 0.001855 35 Protein-protein-interaction for SNIP1 www.ncbi.nlm.ni...
Null ppi.EIF3F View Gene Set 1.833e-05 25 0.001855 35 Protein-protein-interaction for EIF3F www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 1.961e-05 21 0.001905 37 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.RRP1B View Gene Set 2.559e-05 21 0.00242 38 Protein-protein-interaction for RRP1B www.ncbi.nlm.ni...
Null ppi.SUMO2 View Gene Set 2.75e-05 55 0.002535 39 Protein-protein-interaction for SUMO2 www.ncbi.nlm.ni...
Null ppi.USP14 View Gene Set 3.181e-05 22 0.002858 40 Protein-protein-interaction for USP14 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 3.423e-05 15 0.003 41 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.MDC1 View Gene Set 3.615e-05 24 0.003093 42 Protein-protein-interaction for MDC1 www.ncbi.nlm.ni...
Null ppi.UPF2 View Gene Set 4.024e-05 19 0.003364 43 Protein-protein-interaction for UPF2 www.ncbi.nlm.ni...
Null ppi.RAD50 View Gene Set 4.589e-05 21 0.003585 44 Protein-protein-interaction for RAD50 www.ncbi.nlm.ni...
Null ppi.NAA38 View Gene Set 4.522e-05 28 0.003585 44 Protein-protein-interaction for NAA38 www.ncbi.nlm.ni...
Null ppi.TERF2 View Gene Set 4.441e-05 10 0.003585 44 Protein-protein-interaction for TERF2 www.ncbi.nlm.ni...
Null ppi.DCLRE1C View Gene Set 4.772e-05 8 0.003588 47 Protein-protein-interaction for DCLRE1C www.ncbi.nlm.ni...
Null ppi.GTF3C3 View Gene Set 4.792e-05 12 0.003588 47 Protein-protein-interaction for GTF3C3 www.ncbi.nlm.ni...
Null ppi.MLH1 View Gene Set 5.724e-05 12 0.004198 49 Protein-protein-interaction for MLH1 www.ncbi.nlm.ni...
Null ppi.PAXIP1 View Gene Set 6.237e-05 19 0.004447 50 Protein-protein-interaction for PAXIP1 www.ncbi.nlm.ni...
Null ppi.MCPH1 View Gene Set 6.311e-05 17 0.004447 50 Protein-protein-interaction for MCPH1 www.ncbi.nlm.ni...
Null ppi.TADA3 View Gene Set 6.909e-05 21 0.004527 52 Protein-protein-interaction for TADA3 www.ncbi.nlm.ni...
Null ppi.RNPS1 View Gene Set 7.114e-05 44 0.004527 52 Protein-protein-interaction for RNPS1 www.ncbi.nlm.ni...
Null ppi.PABPC1 View Gene Set 6.696e-05 37 0.004527 52 Protein-protein-interaction for PABPC1 www.ncbi.nlm.ni...
Null ppi.SUMO4 View Gene Set 7.019e-05 76 0.004527 52 Protein-protein-interaction for SUMO4 www.ncbi.nlm.ni...
Null ppi.TAF10 View Gene Set 7.179e-05 29 0.004527 52 Protein-protein-interaction for TAF10 www.ncbi.nlm.ni...
Null ppi.CDC20 View Gene Set 6.815e-05 5 0.004527 52 Protein-protein-interaction for CDC20 www.ncbi.nlm.ni...
Null ppi.PSMD7 View Gene Set 7.778e-05 13 0.00482 58 Protein-protein-interaction for PSMD7 www.ncbi.nlm.ni...
Null ppi.EIF3H View Gene Set 8.072e-05 16 0.004917 59 Protein-protein-interaction for EIF3H www.ncbi.nlm.ni...
Null ppi.PSMD10 View Gene Set 8.249e-05 16 0.004941 60 Protein-protein-interaction for PSMD10 www.ncbi.nlm.ni...
Null ppi.CDC16 View Gene Set 8.732e-05 14 0.005145 61 Protein-protein-interaction for CDC16 www.ncbi.nlm.ni...
Null ppi.RPAP3 View Gene Set 8.912e-05 30 0.005166 62 Protein-protein-interaction for RPAP3 www.ncbi.nlm.ni...
Null ppi.PAAF1 View Gene Set 9.575e-05 20 0.005462 63 Protein-protein-interaction for PAAF1 www.ncbi.nlm.ni...
Null ppi.RAD17 View Gene Set 0.0001145 14 0.006433 64 Protein-protein-interaction for RAD17 www.ncbi.nlm.ni...
Null ppi.USP42 View Gene Set 0.0001186 24 0.006558 65 Protein-protein-interaction for USP42 www.ncbi.nlm.ni...
Null ppi.SUPT3H View Gene Set 0.000121 14 0.006588 66 Protein-protein-interaction for SUPT3H www.ncbi.nlm.ni...
Null ppi.SF3B1 View Gene Set 0.0001234 31 0.006618 67 Protein-protein-interaction for SF3B1 www.ncbi.nlm.ni...
Null ppi.C20orf20 View Gene Set 0.0001264 16 0.006682 68 Protein-protein-interaction for C20orf20 www.ncbi.nlm.ni...
Null ppi.RPAP1 View Gene Set 0.0001354 24 0.007052 69 Protein-protein-interaction for RPAP1 www.ncbi.nlm.ni...
Null ppi.SGOL1 View Gene Set 0.0001442 24 0.007222 70 Protein-protein-interaction for SGOL1 www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 0.0001447 20 0.007222 70 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.YY1 View Gene Set 0.0001417 39 0.007222 70 Protein-protein-interaction for YY1 www.ncbi.nlm.ni...
Null ppi.USP39 View Gene Set 0.0001509 16 0.007429 73 Protein-protein-interaction for USP39 www.ncbi.nlm.ni...
Null ppi.ATXN7 View Gene Set 0.0001568 11 0.007618 74 Protein-protein-interaction for ATXN7 www.ncbi.nlm.ni...
Null ppi.CHTF18 View Gene Set 0.0001598 13 0.007656 75 Protein-protein-interaction for CHTF18 www.ncbi.nlm.ni...
Null ppi.POLR3C View Gene Set 0.0001995 10 0.009435 76 Protein-protein-interaction for POLR3C www.ncbi.nlm.ni...
Null ppi.SYNCRIP View Gene Set 0.000223 22 0.01014 77 Protein-protein-interaction for SYNCRIP www.ncbi.nlm.ni...
Null ppi.TP53BP1 View Gene Set 0.0002207 17 0.01014 77 Protein-protein-interaction for TP53BP1 www.ncbi.nlm.ni...
Null ppi.MCM8 View Gene Set 0.0002202 6 0.01014 77 Protein-protein-interaction for MCM8 www.ncbi.nlm.ni...
Null ppi.MSH2 View Gene Set 0.000265 20 0.01184 80 Protein-protein-interaction for MSH2 www.ncbi.nlm.ni...
Null ppi.HIST2H2AC View Gene Set 0.0002669 14 0.01184 80 Protein-protein-interaction for HIST2H2AC www.ncbi.nlm.ni...
Null ppi.PPARGC1A View Gene Set 0.000287 39 0.01247 82 Protein-protein-interaction for PPARGC1A www.ncbi.nlm.ni...
Null ppi.TPX2 View Gene Set 0.0002949 5 0.01247 82 Protein-protein-interaction for TPX2 www.ncbi.nlm.ni...
Null ppi.PRMT1 View Gene Set 0.0002888 17 0.01247 82 Protein-protein-interaction for PRMT1 www.ncbi.nlm.ni...
Null ppi.BRF2 View Gene Set 0.0002939 25 0.01247 82 Protein-protein-interaction for BRF2 www.ncbi.nlm.ni...
Null ppi.TACC2 View Gene Set 0.0003055 10 0.01262 86 Protein-protein-interaction for TACC2 www.ncbi.nlm.ni...
Null ppi.PSMA7 View Gene Set 0.0003033 12 0.01262 86 Protein-protein-interaction for PSMA7 www.ncbi.nlm.ni...
Null ppi.SRPK2 View Gene Set 0.0003221 7 0.01316 88 Protein-protein-interaction for SRPK2 www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 0.0003463 12 0.01399 89 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.PRPF19 View Gene Set 0.0003517 9 0.01404 90 Protein-protein-interaction for PRPF19 www.ncbi.nlm.ni...
Null ppi.SRPK1 View Gene Set 0.0003745 12 0.01463 91 Protein-protein-interaction for SRPK1 www.ncbi.nlm.ni...
Null ppi.SIP1 View Gene Set 0.000372 17 0.01463 91 Protein-protein-interaction for SIP1 www.ncbi.nlm.ni...
Null ppi.SF3A2 View Gene Set 0.0003806 16 0.01471 93 Protein-protein-interaction for SF3A2 www.ncbi.nlm.ni...
Null ppi.PLK1 View Gene Set 0.0004263 22 0.01613 94 Protein-protein-interaction for PLK1 www.ncbi.nlm.ni...
Null ppi.RUVBL1 View Gene Set 0.0004248 41 0.01613 94 Protein-protein-interaction for RUVBL1 www.ncbi.nlm.ni...
Null ppi.TTR View Gene Set 0.0004436 13 0.01654 96 Protein-protein-interaction for TTR www.ncbi.nlm.ni...
Null ppi.WDR77 View Gene Set 0.0004465 18 0.01654 96 Protein-protein-interaction for WDR77 www.ncbi.nlm.ni...
Null ppi.NUP98 View Gene Set 0.0004616 12 0.01663 98 Protein-protein-interaction for NUP98 www.ncbi.nlm.ni...
Null ppi.RAN View Gene Set 0.0004627 15 0.01663 98 Protein-protein-interaction for RAN www.ncbi.nlm.ni...
Null ppi.HIST2H2BE View Gene Set 0.0004596 27 0.01663 98 Protein-protein-interaction for HIST2H2BE www.ncbi.nlm.ni...
Null ppi.NCBP2 View Gene Set 0.0004875 6 0.01669 101 Protein-protein-interaction for NCBP2 www.ncbi.nlm.ni...
Null ppi.GAR1 View Gene Set 0.0004701 10 0.01669 101 Protein-protein-interaction for GAR1 www.ncbi.nlm.ni...
Null ppi.RAD51 View Gene Set 0.000481 20 0.01669 101 Protein-protein-interaction for RAD51 www.ncbi.nlm.ni...
Null ppi.POLR1E View Gene Set 0.000478 13 0.01669 101 Protein-protein-interaction for POLR1E www.ncbi.nlm.ni...
Null ppi.AURKA View Gene Set 0.0004872 16 0.01669 101 Protein-protein-interaction for AURKA www.ncbi.nlm.ni...
Null ppi.TOR1AIP2 View Gene Set 0.0004948 7 0.0167 106 Protein-protein-interaction for TOR1AIP2 www.ncbi.nlm.ni...
Null ppi.ZRANB2 View Gene Set 0.0004972 11 0.0167 106 Protein-protein-interaction for ZRANB2 www.ncbi.nlm.ni...
Null ppi.PDS5A View Gene Set 0.0005347 6 0.01723 108 Protein-protein-interaction for PDS5A www.ncbi.nlm.ni...
Null ppi.GEMIN5 View Gene Set 0.0005234 14 0.01723 108 Protein-protein-interaction for GEMIN5 www.ncbi.nlm.ni...
Null ppi.COPS7A View Gene Set 0.0005333 19 0.01723 108 Protein-protein-interaction for COPS7A www.ncbi.nlm.ni...
Null ppi.DDX56 View Gene Set 0.0005369 20 0.01723 108 Protein-protein-interaction for DDX56 www.ncbi.nlm.ni...
Null ppi.PSMA2 View Gene Set 0.0005351 6 0.01723 108 Protein-protein-interaction for PSMA2 www.ncbi.nlm.ni...
Null ppi.NOL12 View Gene Set 0.0005501 7 0.0174 113 Protein-protein-interaction for NOL12 www.ncbi.nlm.ni...
Null ppi.GEMIN6 View Gene Set 0.0005519 14 0.0174 113 Protein-protein-interaction for GEMIN6 www.ncbi.nlm.ni...
Null ppi.PRKDC View Gene Set 0.0005709 49 0.01784 115 Protein-protein-interaction for PRKDC www.ncbi.nlm.ni...
Null ppi.THAP1 View Gene Set 0.0005761 12 0.01785 116 Protein-protein-interaction for THAP1 www.ncbi.nlm.ni...
Null ppi.MUS81 View Gene Set 0.000596 6 0.01831 117 Protein-protein-interaction for MUS81 www.ncbi.nlm.ni...
Null ppi.FEN1 View Gene Set 0.0006124 11 0.01849 118 Protein-protein-interaction for FEN1 www.ncbi.nlm.ni...
Null ppi.C16orf53 View Gene Set 0.0006123 9 0.01849 118 Protein-protein-interaction for C16orf53 www.ncbi.nlm.ni...
Null ppi.LSM2 View Gene Set 0.000635 26 0.01902 120 Protein-protein-interaction for LSM2 www.ncbi.nlm.ni...
Null ppi.PHF17 View Gene Set 0.0006445 8 0.01914 121 Protein-protein-interaction for PHF17 www.ncbi.nlm.ni...
Null ppi.TERF1 View Gene Set 0.0006527 18 0.01923 122 Protein-protein-interaction for TERF1 www.ncbi.nlm.ni...
Null ppi.PSMB7 View Gene Set 0.0006668 6 0.0194 123 Protein-protein-interaction for PSMB7 www.ncbi.nlm.ni...
Null ppi.TTI1 View Gene Set 0.0006693 8 0.0194 123 Protein-protein-interaction for TTI1 www.ncbi.nlm.ni...
Null ppi.COPS8 View Gene Set 0.0006931 13 0.01977 125 Protein-protein-interaction for COPS8 www.ncbi.nlm.ni...
Null ppi.TAF1D View Gene Set 0.0006885 21 0.01977 125 Protein-protein-interaction for TAF1D www.ncbi.nlm.ni...
Null ppi.SNUPN View Gene Set 0.0007184 12 0.02017 127 Protein-protein-interaction for SNUPN www.ncbi.nlm.ni...
Null ppi.RBMX View Gene Set 0.000724 15 0.02017 127 Protein-protein-interaction for RBMX www.ncbi.nlm.ni...
Null ppi.WWOX View Gene Set 0.0007231 26 0.02017 127 Protein-protein-interaction for WWOX www.ncbi.nlm.ni...
Null ppi.PSMB5 View Gene Set 0.0007332 8 0.02027 130 Protein-protein-interaction for PSMB5 www.ncbi.nlm.ni...
Null ppi.PCBD1 View Gene Set 0.0007451 6 0.02044 131 Protein-protein-interaction for PCBD1 www.ncbi.nlm.ni...
Null ppi.PPP4R2 View Gene Set 0.000751 7 0.02045 132 Protein-protein-interaction for PPP4R2 www.ncbi.nlm.ni...
Null ppi.DDX20 View Gene Set 0.0007956 26 0.0215 133 Protein-protein-interaction for DDX20 www.ncbi.nlm.ni...
Null ppi.SF3B3 View Gene Set 0.000811 19 0.02159 134 Protein-protein-interaction for SF3B3 www.ncbi.nlm.ni...
Null ppi.850620 View Gene Set 0.0008061 20 0.02159 134 Protein-protein-interaction for 850620 www.ncbi.nlm.ni...
Null ppi.XPO1 View Gene Set 0.0008312 43 0.02197 136 Protein-protein-interaction for XPO1 www.ncbi.nlm.ni...
Null ppi.NBN View Gene Set 0.0008392 16 0.02201 137 Protein-protein-interaction for NBN www.ncbi.nlm.ni...
Null ppi.EIF2S2 View Gene Set 0.0008459 17 0.02203 138 Protein-protein-interaction for EIF2S2 www.ncbi.nlm.ni...
Null ppi.NUP43 View Gene Set 0.0008555 6 0.02212 139 Protein-protein-interaction for NUP43 www.ncbi.nlm.ni...
Null ppi.CTCF View Gene Set 0.0008812 11 0.02262 140 Protein-protein-interaction for CTCF www.ncbi.nlm.ni...
Null ppi.SMAD6 View Gene Set 0.0009018 8 0.02266 141 Protein-protein-interaction for SMAD6 www.ncbi.nlm.ni...
Null ppi.MGMT View Gene Set 0.0008978 28 0.02266 141 Protein-protein-interaction for MGMT www.ncbi.nlm.ni...
Null ppi.ORC5L View Gene Set 0.0008972 11 0.02266 141 Protein-protein-interaction for ORC5L www.ncbi.nlm.ni...
Null ppi.HNRNPUL1 View Gene Set 0.0009494 11 0.0237 144 Protein-protein-interaction for HNRNPUL1 www.ncbi.nlm.ni...
Null ppi.XRN1 View Gene Set 0.0009565 25 0.02371 145 Protein-protein-interaction for XRN1 www.ncbi.nlm.ni...
Null ppi.THOC4 View Gene Set 0.0009867 5 0.02412 146 Protein-protein-interaction for THOC4 www.ncbi.nlm.ni...
Null ppi.CDC45 View Gene Set 0.0009806 13 0.02412 146 Protein-protein-interaction for CDC45 www.ncbi.nlm.ni...
Null ppi.NDRG1 View Gene Set 0.001018 58 0.02473 148 Protein-protein-interaction for NDRG1 www.ncbi.nlm.ni...
Null ppi.USP19 View Gene Set 0.001059 17 0.02521 149 Protein-protein-interaction for USP19 www.ncbi.nlm.ni...
Null ppi.MDM4 View Gene Set 0.001054 15 0.02521 149 Protein-protein-interaction for MDM4 www.ncbi.nlm.ni...
Null ppi.WDR33 View Gene Set 0.001048 14 0.02521 149 Protein-protein-interaction for WDR33 www.ncbi.nlm.ni...
Null ppi.ZMYM2 View Gene Set 0.001068 20 0.02526 152 Protein-protein-interaction for ZMYM2 www.ncbi.nlm.ni...
Null ppi.KLF13 View Gene Set 0.001102 10 0.02588 153 Protein-protein-interaction for KLF13 www.ncbi.nlm.ni...
Null ppi.CDCA5 View Gene Set 0.001142 6 0.02664 154 Protein-protein-interaction for CDCA5 www.ncbi.nlm.ni...
Null ppi.CXXC1 View Gene Set 0.00116 14 0.02689 155 Protein-protein-interaction for CXXC1 www.ncbi.nlm.ni...
Null ppi.XRCC3 View Gene Set 0.001169 6 0.02693 156 Protein-protein-interaction for XRCC3 www.ncbi.nlm.ni...
Null ppi.SERTAD2 View Gene Set 0.001179 6 0.027 157 Protein-protein-interaction for SERTAD2 www.ncbi.nlm.ni...
Null ppi.ATXN3 View Gene Set 0.00122 7 0.02759 158 Protein-protein-interaction for ATXN3 www.ncbi.nlm.ni...
Null ppi.MYST1 View Gene Set 0.001219 14 0.02759 158 Protein-protein-interaction for MYST1 www.ncbi.nlm.ni...
Null ppi.ORC1L View Gene Set 0.001229 11 0.02761 160 Protein-protein-interaction for ORC1L www.ncbi.nlm.ni...
Null ppi.SNORD3A View Gene Set 0.001242 9 0.02772 161 Protein-protein-interaction for SNORD3A www.ncbi.nlm.ni...
Null ppi.CD2BP2 View Gene Set 0.001254 15 0.02783 162 Protein-protein-interaction for CD2BP2 www.ncbi.nlm.ni...
Null ppi.PUF60 View Gene Set 0.001285 35 0.02821 163 Protein-protein-interaction for PUF60 www.ncbi.nlm.ni...
Null ppi.MLL View Gene Set 0.001287 17 0.02821 163 Protein-protein-interaction for MLL www.ncbi.nlm.ni...
Null ppi.FAF2 View Gene Set 0.001335 8 0.02907 165 Protein-protein-interaction for FAF2 www.ncbi.nlm.ni...
Null ppi.RPP14 View Gene Set 0.001357 6 0.02939 166 Protein-protein-interaction for RPP14 www.ncbi.nlm.ni...
Null ppi.ZNF655 View Gene Set 0.001387 8 0.02984 167 Protein-protein-interaction for ZNF655 www.ncbi.nlm.ni...
Null ppi.HIST1H3A View Gene Set 0.0014 31 0.02994 168 Protein-protein-interaction for HIST1H3A www.ncbi.nlm.ni...
Null ppi.HNRNPL View Gene Set 0.001452 9 0.03068 169 Protein-protein-interaction for HNRNPL www.ncbi.nlm.ni...
Null ppi.POLR3E View Gene Set 0.00146 6 0.03068 169 Protein-protein-interaction for POLR3E www.ncbi.nlm.ni...
Null ppi.THOC7 View Gene Set 0.001456 7 0.03068 169 Protein-protein-interaction for THOC7 www.ncbi.nlm.ni...
Null ppi.SUB1 View Gene Set 0.00147 14 0.03071 172 Protein-protein-interaction for SUB1 www.ncbi.nlm.ni...
Null ppi.COPS6 View Gene Set 0.001485 73 0.03084 173 Protein-protein-interaction for COPS6 www.ncbi.nlm.ni...
Null ppi.LSM1 View Gene Set 0.001528 18 0.03136 174 Protein-protein-interaction for LSM1 www.ncbi.nlm.ni...
Null ppi.ANAPC2 View Gene Set 0.001536 8 0.03136 174 Protein-protein-interaction for ANAPC2 www.ncbi.nlm.ni...
Null ppi.RNMTL1 View Gene Set 0.001529 8 0.03136 174 Protein-protein-interaction for RNMTL1 www.ncbi.nlm.ni...
Null ppi.EP400 View Gene Set 0.001549 11 0.03145 177 Protein-protein-interaction for EP400 www.ncbi.nlm.ni...
Null ppi.NCBP1 View Gene Set 0.001571 8 0.03167 178 Protein-protein-interaction for NCBP1 www.ncbi.nlm.ni...
Null ppi.COPS7B View Gene Set 0.001584 8 0.03167 178 Protein-protein-interaction for COPS7B www.ncbi.nlm.ni...
Null ppi.UPF3A View Gene Set 0.001586 18 0.03167 178 Protein-protein-interaction for UPF3A www.ncbi.nlm.ni...
Null ppi.PTTG1 View Gene Set 0.001609 13 0.03195 181 Protein-protein-interaction for PTTG1 www.ncbi.nlm.ni...
Null ppi.CPSF6 View Gene Set 0.001621 13 0.03202 182 Protein-protein-interaction for CPSF6 www.ncbi.nlm.ni...
Null ppi.TRRAP View Gene Set 0.001662 21 0.03263 183 Protein-protein-interaction for TRRAP www.ncbi.nlm.ni...
Null ppi.WDR48 View Gene Set 0.001685 52 0.03273 184 Protein-protein-interaction for WDR48 www.ncbi.nlm.ni...
Null ppi.DNAJC7 View Gene Set 0.001681 8 0.03273 184 Protein-protein-interaction for DNAJC7 www.ncbi.nlm.ni...
Null ppi.MYSM1 View Gene Set 0.001749 13 0.03362 186 Protein-protein-interaction for MYSM1 www.ncbi.nlm.ni...
Null ppi.LEF1 View Gene Set 0.00174 23 0.03362 186 Protein-protein-interaction for LEF1 www.ncbi.nlm.ni...
Null ppi.MELK View Gene Set 0.001763 8 0.0337 188 Protein-protein-interaction for MELK www.ncbi.nlm.ni...
Null ppi.POP1 View Gene Set 0.001845 6 0.03453 189 Protein-protein-interaction for POP1 www.ncbi.nlm.ni...
Null ppi.HIST2H3C View Gene Set 0.001819 31 0.03453 189 Protein-protein-interaction for HIST2H3C www.ncbi.nlm.ni...
Null ppi.EIF5 View Gene Set 0.001836 6 0.03453 189 Protein-protein-interaction for EIF5 www.ncbi.nlm.ni...
Null ppi.MED9 View Gene Set 0.001841 33 0.03453 189 Protein-protein-interaction for MED9 www.ncbi.nlm.ni...
Null ppi.ING3 View Gene Set 0.001901 12 0.03504 193 Protein-protein-interaction for ING3 www.ncbi.nlm.ni...
Null ppi.PINX1 View Gene Set 0.001895 20 0.03504 193 Protein-protein-interaction for PINX1 www.ncbi.nlm.ni...
Null ppi.PSMA4 View Gene Set 0.001901 9 0.03504 193 Protein-protein-interaction for PSMA4 www.ncbi.nlm.ni...
Null ppi.CCT3 View Gene Set 0.001935 15 0.03547 196 Protein-protein-interaction for CCT3 www.ncbi.nlm.ni...
Null ppi.MIS12 View Gene Set 0.002006 9 0.03659 197 Protein-protein-interaction for MIS12 www.ncbi.nlm.ni...
Null ppi.JMY View Gene Set 0.002039 7 0.03687 198 Protein-protein-interaction for JMY www.ncbi.nlm.ni...
Null ppi.SNRPF View Gene Set 0.002041 6 0.03687 198 Protein-protein-interaction for SNRPF www.ncbi.nlm.ni...
Null ppi.TGS1 View Gene Set 0.00207 8 0.0372 200 Protein-protein-interaction for TGS1 www.ncbi.nlm.ni...

Gene Set Collection: pathwayCommons.cell-map

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null TNF alpha/NF-kB View Gene Set 0.002205 170 0.02205 1 CELL_MAP - TNF alpha/NF-kB gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.humancyc

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null folate polyglutamylation View Gene Set 0.0006576 5 0.04916 1 HUMANCYC - folate polyglutamylation gene set www.pathwaycomm...
Null purine nucleotides de novo biosynthesis II View Gene Set 0.0007563 11 0.04916 1 HUMANCYC - purine nucleotides de novo biosynthesis II gene set www.pathwaycomm...
Null pyrimidine deoxyribonucleotides de novo biosynthesis View Gene Set 0.0004073 14 0.04916 1 HUMANCYC - pyrimidine deoxyribonucleotides de novo biosynthesis gene set www.pathwaycomm...
Null pyrimidine ribonucleotides de novo biosynthesis View Gene Set 0.0002273 11 0.04916 1 HUMANCYC - pyrimidine ribonucleotides de novo biosynthesis gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.nci-nature

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Validated targets of C-MYC transcriptional activation View Gene Set 8.866e-11 80 1.649e-08 1 NCI_NATURE - Validated targets of C-MYC transcriptional activation gene set www.pathwaycomm...
Null Aurora B signaling View Gene Set 3.234e-07 41 3.008e-05 2 NCI_NATURE - Aurora B signaling gene set www.pathwaycomm...
Null Polo-like kinase signaling events in the cell cycle View Gene Set 7.475e-07 109 4.634e-05 3 NCI_NATURE - Polo-like kinase signaling events in the cell cycle gene set www.pathwaycomm...
Null PLK1 signaling events View Gene Set 1.012e-06 104 4.708e-05 4 NCI_NATURE - PLK1 signaling events gene set www.pathwaycomm...
Null Signaling by Aurora kinases View Gene Set 1.949e-06 98 7.252e-05 5 NCI_NATURE - Signaling by Aurora kinases gene set www.pathwaycomm...
Null C-MYC pathway View Gene Set 4.39e-06 149 0.0001361 6 NCI_NATURE - C-MYC pathway gene set www.pathwaycomm...
Null Regulation of Telomerase View Gene Set 2.895e-05 68 0.0007692 7 NCI_NATURE - Regulation of Telomerase gene set www.pathwaycomm...
Null E2F transcription factor network View Gene Set 0.001358 73 0.03157 8 NCI_NATURE - E2F transcription factor network gene set www.pathwaycomm...
Null FOXM1 transcription factor network View Gene Set 0.001999 42 0.04131 9 NCI_NATURE - FOXM1 transcription factor network gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.reactome

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Gene Expression View Gene Set 4.698e-44 381 5.248e-41 1 REACTOME - Gene Expression gene set www.pathwaycomm...
Null Mitotic M-M/G1 phases View Gene Set 1.106e-36 180 6.179e-34 2 REACTOME - Mitotic M-M/G1 phases gene set www.pathwaycomm...
Null DNA Replication View Gene Set 1.755e-36 200 6.535e-34 3 REACTOME - DNA Replication gene set www.pathwaycomm...
Null Cell Cycle Mitotic View Gene Set 1.289e-35 312 3.6e-33 4 REACTOME - Cell Cycle Mitotic gene set www.pathwaycomm... Mitotic&format=...
Null Processing of Capped Intron-Containing Pre-mRNA View Gene Set 1.523e-28 138 3.403e-26 5 REACTOME - Processing of Capped Intron-Containing Pre-mRNA gene set www.pathwaycomm...
Null mRNA Processing View Gene Set 3.537e-26 158 6.585e-24 6 REACTOME - mRNA Processing gene set www.pathwaycomm...
Null Formation and Maturation of mRNA Transcript View Gene Set 4.74e-26 185 7.564e-24 7 REACTOME - Formation and Maturation of mRNA Transcript gene set www.pathwaycomm...
Null M Phase View Gene Set 1.94e-23 90 2.709e-21 8 REACTOME - M Phase gene set www.pathwaycomm...
Null mRNA Splicing - Major Pathway View Gene Set 3.265e-23 107 3.648e-21 9 REACTOME - mRNA Splicing - Major Pathway gene set www.pathwaycomm...
Null mRNA Splicing View Gene Set 3.265e-23 107 3.648e-21 9 REACTOME - mRNA Splicing gene set www.pathwaycomm...
Null Metabolism of RNA View Gene Set 4.581e-22 174 4.651e-20 11 REACTOME - Metabolism of RNA gene set www.pathwaycomm...
Null Mitotic Prometaphase View Gene Set 7.075e-22 86 6.586e-20 12 REACTOME - Mitotic Prometaphase gene set www.pathwaycomm...
Null Cell Cycle Checkpoints View Gene Set 1.535e-17 124 1.318e-15 13 REACTOME - Cell Cycle Checkpoints gene set www.pathwaycomm...
Null DNA Replication Pre-Initiation View Gene Set 1.422e-15 90 1.059e-13 14 REACTOME - DNA Replication Pre-Initiation gene set www.pathwaycomm...
Null M/G1 Transition View Gene Set 1.422e-15 90 1.059e-13 14 REACTOME - M/G1 Transition gene set www.pathwaycomm...
Null Translation View Gene Set 4.765e-15 120 3.327e-13 16 REACTOME - Translation gene set www.pathwaycomm...
Null Assembly of the pre-replicative complex View Gene Set 4.501e-14 75 2.958e-12 17 REACTOME - Assembly of the pre-replicative complex gene set www.pathwaycomm...
Null Regulation of mitotic cell cycle View Gene Set 6.65e-14 95 3.714e-12 18 REACTOME - Regulation of mitotic cell cycle gene set www.pathwaycomm...
Null APC/C-mediated degradation of cell cycle proteins View Gene Set 6.65e-14 95 3.714e-12 18 REACTOME - APC/C-mediated degradation of cell cycle proteins gene set www.pathwaycomm...
Null Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 6.56e-14 86 3.714e-12 18 REACTOME - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null Influenza Infection View Gene Set 1.243e-13 143 6.038e-12 21 REACTOME - Influenza Infection gene set www.pathwaycomm...
Null S Phase View Gene Set 1.157e-13 113 6.038e-12 21 REACTOME - S Phase gene set www.pathwaycomm...
Null Synthesis of DNA View Gene Set 1.203e-13 102 6.038e-12 21 REACTOME - Synthesis of DNA gene set www.pathwaycomm...
Null G1/S Transition View Gene Set 3.124e-13 104 1.454e-11 24 REACTOME - G1/S Transition gene set www.pathwaycomm...
Null Cap-dependent Translation Initiation View Gene Set 3.645e-13 113 1.566e-11 25 REACTOME - Cap-dependent Translation Initiation gene set www.pathwaycomm...
Null Eukaryotic Translation Initiation View Gene Set 3.645e-13 113 1.566e-11 25 REACTOME - Eukaryotic Translation Initiation gene set www.pathwaycomm...
Null Mitotic G1-G1/S phases View Gene Set 3.886e-13 113 1.608e-11 27 REACTOME - Mitotic G1-G1/S phases gene set www.pathwaycomm...
Null Regulation of APC/C activators between G1/S and early anaphase View Gene Set 7.146e-13 88 2.851e-11 28 REACTOME - Regulation of APC/C activators between G1/S and early anaphase gene set www.pathwaycomm...
Null Metabolism of mRNA View Gene Set 9.038e-13 125 3.481e-11 29 REACTOME - Metabolism of mRNA gene set www.pathwaycomm...
Null Transport of Mature mRNA derived from an Intron-Containing Transcript View Gene Set 1.206e-12 51 4.492e-11 30 REACTOME - Transport of Mature mRNA derived from an Intron-Containing Transcript gene set www.pathwaycomm...
Null Transport of Mature Transcript to Cytoplasm View Gene Set 1.496e-12 55 5.39e-11 31 REACTOME - Transport of Mature Transcript to Cytoplasm gene set www.pathwaycomm...
Null Influenza Life Cycle View Gene Set 1.56e-12 138 5.446e-11 32 REACTOME - Influenza Life Cycle gene set www.pathwaycomm...
Null Regulation of DNA replication View Gene Set 1.978e-12 81 6.696e-11 33 REACTOME - Regulation of DNA replication gene set www.pathwaycomm...
Null GTP hydrolysis and joining of the 60S ribosomal subunit View Gene Set 4.077e-12 106 1.34e-10 34 REACTOME - GTP hydrolysis and joining of the 60S ribosomal subunit gene set www.pathwaycomm...
Null snRNP Assembly View Gene Set 4.661e-12 50 1.446e-10 35 REACTOME - snRNP Assembly gene set www.pathwaycomm...
Null Metabolism of non-coding RNA View Gene Set 4.661e-12 50 1.446e-10 35 REACTOME - Metabolism of non-coding RNA gene set www.pathwaycomm...
Null APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 View Gene Set 9.693e-12 77 2.926e-10 37 REACTOME - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 gene set www.pathwaycomm...
Null 3' -UTR-mediated translational regulation View Gene Set 1.088e-11 105 3.115e-10 38 REACTOME - 3' -UTR-mediated translational regulation gene set www.pathwaycomm...
Null L13a-mediated translational silencing of Ceruloplasmin expression View Gene Set 1.088e-11 105 3.115e-10 38 REACTOME - L13a-mediated translational silencing of Ceruloplasmin expression gene set www.pathwaycomm...
Null HIV Infection View Gene Set 1.583e-11 194 4.344e-10 40 REACTOME - HIV Infection gene set www.pathwaycomm...
Null Removal of licensing factors from origins View Gene Set 1.595e-11 78 4.344e-10 40 REACTOME - Removal of licensing factors from origins gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 2.124e-11 77 5.649e-10 42 REACTOME - APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null CDT1 association with the CDC6:ORC:origin complex View Gene Set 2.638e-11 66 6.853e-10 43 REACTOME - CDT1 association with the CDC6:ORC:origin complex gene set www.pathwaycomm...
Null Post-Elongation Processing of the Transcript View Gene Set 4.662e-11 43 1.132e-09 44 REACTOME - Post-Elongation Processing of the Transcript gene set www.pathwaycomm...
Null Cleavage of Growing Transcript in the Termination Region View Gene Set 4.662e-11 43 1.132e-09 44 REACTOME - Cleavage of Growing Transcript in the Termination Region gene set www.pathwaycomm...
Null RNA Polymerase II Transcription Termination View Gene Set 4.662e-11 43 1.132e-09 44 REACTOME - RNA Polymerase II Transcription Termination gene set www.pathwaycomm...
Null Switching of origins to a post-replicative state View Gene Set 6.034e-11 76 1.404e-09 47 REACTOME - Switching of origins to a post-replicative state gene set www.pathwaycomm...
Null Orc1 removal from chromatin View Gene Set 6.034e-11 76 1.404e-09 47 REACTOME - Orc1 removal from chromatin gene set www.pathwaycomm...
Null Host Interactions of HIV factors View Gene Set 8.891e-11 132 2.027e-09 49 REACTOME - Host Interactions of HIV factors gene set www.pathwaycomm...
Null p53-Independent G1/S DNA damage checkpoint View Gene Set 1.299e-10 62 2.798e-09 50 REACTOME - p53-Independent G1/S DNA damage checkpoint gene set www.pathwaycomm...
Null p53-Independent DNA Damage Response View Gene Set 1.299e-10 62 2.798e-09 50 REACTOME - p53-Independent DNA Damage Response gene set www.pathwaycomm...
Null Cdc20:Phospho-APC/C mediated degradation of Cyclin A View Gene Set 1.302e-10 75 2.798e-09 50 REACTOME - Cdc20:Phospho-APC/C mediated degradation of Cyclin A gene set www.pathwaycomm...
Null Regulation of mRNA Stability by Proteins that Bind AU-rich Elements View Gene Set 2.961e-10 95 6.241e-09 53 REACTOME - Regulation of mRNA Stability by Proteins that Bind AU-rich Elements gene set www.pathwaycomm...
Null G2/M Checkpoints View Gene Set 3.422e-10 43 6.949e-09 54 REACTOME - G2/M Checkpoints gene set www.pathwaycomm...
Null Ubiquitin Mediated Degradation of Phosphorylated Cdc25A View Gene Set 3.403e-10 61 6.949e-09 54 REACTOME - Ubiquitin Mediated Degradation of Phosphorylated Cdc25A gene set www.pathwaycomm...
Null Transcription View Gene Set 4.043e-10 178 8.065e-09 56 REACTOME - Transcription gene set www.pathwaycomm...
Null Destabilization of mRNA by AUF1 (hnRNP D0) View Gene Set 5.172e-10 63 1.014e-08 57 REACTOME - Destabilization of mRNA by AUF1 (hnRNP D0) gene set www.pathwaycomm...
Null SCF-beta-TrCP mediated degradation of Emi1 View Gene Set 7.34e-10 60 1.414e-08 58 REACTOME - SCF-beta-TrCP mediated degradation of Emi1 gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of Securin View Gene Set 8.182e-10 72 1.549e-08 59 REACTOME - APC/C:Cdc20 mediated degradation of Securin gene set www.pathwaycomm...
Null Formation of a pool of free 40S subunits View Gene Set 8.375e-10 95 1.559e-08 60 REACTOME - Formation of a pool of free 40S subunits gene set www.pathwaycomm...
Null Eukaryotic Translation Elongation View Gene Set 1.374e-09 88 2.516e-08 61 REACTOME - Eukaryotic Translation Elongation gene set www.pathwaycomm...
Null Regulation of activated PAK-2p34 by proteasome mediated degradation View Gene Set 1.884e-09 57 3.395e-08 62 REACTOME - Regulation of activated PAK-2p34 by proteasome mediated degradation gene set www.pathwaycomm...
Null Autodegradation of the E3 ubiquitin ligase COP1 View Gene Set 2.055e-09 60 3.644e-08 63 REACTOME - Autodegradation of the E3 ubiquitin ligase COP1 gene set www.pathwaycomm...
Null Stabilization of p53 View Gene Set 2.239e-09 61 3.907e-08 64 REACTOME - Stabilization of p53 gene set www.pathwaycomm...
Null Vpu mediated degradation of CD4 View Gene Set 2.661e-09 57 4.573e-08 65 REACTOME - Vpu mediated degradation of CD4 gene set www.pathwaycomm...
Null Ubiquitin-dependent degradation of Cyclin D1 View Gene Set 3.512e-09 59 5.854e-08 66 REACTOME - Ubiquitin-dependent degradation of Cyclin D1 gene set www.pathwaycomm...
Null Ubiquitin-dependent degradation of Cyclin D View Gene Set 3.512e-09 59 5.854e-08 66 REACTOME - Ubiquitin-dependent degradation of Cyclin D gene set www.pathwaycomm...
Null Degradation of beta-catenin by the destruction complex View Gene Set 4.273e-09 56 6.819e-08 68 REACTOME - Degradation of beta-catenin by the destruction complex gene set www.pathwaycomm...
Null Signaling by Wnt View Gene Set 4.273e-09 56 6.819e-08 68 REACTOME - Signaling by Wnt gene set www.pathwaycomm...
Null G2/M DNA damage checkpoint View Gene Set 4.242e-09 29 6.819e-08 68 REACTOME - G2/M DNA damage checkpoint gene set www.pathwaycomm...
Null Post-Elongation Processing of Intron-Containing pre-mRNA View Gene Set 6.119e-09 34 9.393e-08 71 REACTOME - Post-Elongation Processing of Intron-Containing pre-mRNA gene set www.pathwaycomm...
Null mRNA 3'-end processing View Gene Set 6.119e-09 34 9.393e-08 71 REACTOME - mRNA 3'-end processing gene set www.pathwaycomm...
Null RNA Polymerase II Transcription View Gene Set 6.139e-09 101 9.393e-08 71 REACTOME - RNA Polymerase II Transcription gene set www.pathwaycomm...
Null Peptide chain elongation View Gene Set 6.576e-09 85 9.794e-08 74 REACTOME - Peptide chain elongation gene set www.pathwaycomm...
Null CDK-mediated phosphorylation and removal of Cdc6 View Gene Set 6.516e-09 58 9.794e-08 74 REACTOME - CDK-mediated phosphorylation and removal of Cdc6 gene set www.pathwaycomm...
Null Vif-mediated degradation of APOBEC3G View Gene Set 1.042e-08 61 1.512e-07 76 REACTOME - Vif-mediated degradation of APOBEC3G gene set www.pathwaycomm...
Null Eukaryotic Translation Termination View Gene Set 1.041e-08 85 1.512e-07 76 REACTOME - Eukaryotic Translation Termination gene set www.pathwaycomm...
Null Interactions of Rev with host cellular proteins View Gene Set 1.225e-08 33 1.738e-07 78 REACTOME - Interactions of Rev with host cellular proteins gene set www.pathwaycomm...
Null G1/S DNA Damage Checkpoints View Gene Set 1.229e-08 68 1.738e-07 78 REACTOME - G1/S DNA Damage Checkpoints gene set www.pathwaycomm...
Null Regulation of ornithine decarboxylase (ODC) View Gene Set 1.316e-08 62 1.837e-07 80 REACTOME - Regulation of ornithine decarboxylase (ODC) gene set www.pathwaycomm...
Null Chromosome Maintenance View Gene Set 2.203e-08 69 3.038e-07 81 REACTOME - Chromosome Maintenance gene set www.pathwaycomm...
Null Activation of ATR in response to replication stress View Gene Set 2.727e-08 37 3.715e-07 82 REACTOME - Activation of ATR in response to replication stress gene set www.pathwaycomm...
Null Rev-mediated nuclear export of HIV-1 RNA View Gene Set 3.299e-08 32 4.44e-07 83 REACTOME - Rev-mediated nuclear export of HIV-1 RNA gene set www.pathwaycomm...
Null Autodegradation of Cdh1 by Cdh1:APC/C View Gene Set 5.127e-08 67 6.817e-07 84 REACTOME - Autodegradation of Cdh1 by Cdh1:APC/C gene set www.pathwaycomm...
Null mRNA Splicing - Minor Pathway View Gene Set 5.646e-08 42 7.419e-07 85 REACTOME - mRNA Splicing - Minor Pathway gene set www.pathwaycomm...
Null Influenza Viral RNA Transcription and Replication View Gene Set 5.744e-08 101 7.461e-07 86 REACTOME - Influenza Viral RNA Transcription and Replication gene set www.pathwaycomm...
Null p53-Dependent G1/S DNA damage checkpoint View Gene Set 7.667e-08 64 9.732e-07 87 REACTOME - p53-Dependent G1/S DNA damage checkpoint gene set www.pathwaycomm...
Null p53-Dependent G1 DNA Damage Response View Gene Set 7.667e-08 64 9.732e-07 87 REACTOME - p53-Dependent G1 DNA Damage Response gene set www.pathwaycomm...
Null SCF(Skp2)-mediated degradation of p27/p21 View Gene Set 1.305e-07 52 1.638e-06 89 REACTOME - SCF(Skp2)-mediated degradation of p27/p21 gene set www.pathwaycomm...
Null Viral mRNA Translation View Gene Set 1.513e-07 85 1.877e-06 90 REACTOME - Viral mRNA Translation gene set www.pathwaycomm...
Null Nuclear import of Rev protein View Gene Set 1.554e-07 30 1.907e-06 91 REACTOME - Nuclear import of Rev protein gene set www.pathwaycomm...
Null Regulation of Apoptosis View Gene Set 1.843e-07 66 2.237e-06 92 REACTOME - Regulation of Apoptosis gene set www.pathwaycomm...
Null Transport of the SLBP Dependant Mature mRNA View Gene Set 1.868e-07 33 2.244e-06 93 REACTOME - Transport of the SLBP Dependant Mature mRNA gene set www.pathwaycomm...
Null tRNA Aminoacylation View Gene Set 2.497e-07 42 2.968e-06 94 REACTOME - tRNA Aminoacylation gene set www.pathwaycomm...
Null Transport of the SLBP independent Mature mRNA View Gene Set 2.966e-07 32 3.487e-06 95 REACTOME - Transport of the SLBP independent Mature mRNA gene set www.pathwaycomm...
Null Transport of Mature mRNAs Derived from Intronless Transcripts View Gene Set 3.037e-07 36 3.533e-06 96 REACTOME - Transport of Mature mRNAs Derived from Intronless Transcripts gene set www.pathwaycomm...
Null Export of Viral Ribonucleoproteins from Nucleus View Gene Set 3.557e-07 31 4.095e-06 97 REACTOME - Export of Viral Ribonucleoproteins from Nucleus gene set www.pathwaycomm...
Null Activation of the pre-replicative complex View Gene Set 4.203e-07 30 4.791e-06 98 REACTOME - Activation of the pre-replicative complex gene set www.pathwaycomm...
Null NEP/NS2 Interacts with the Cellular Export Machinery View Gene Set 4.695e-07 29 5.297e-06 99 REACTOME - NEP/NS2 Interacts with the Cellular Export Machinery gene set www.pathwaycomm...
Null Transport of Mature mRNA Derived from an Intronless Transcript View Gene Set 4.806e-07 35 5.369e-06 100 REACTOME - Transport of Mature mRNA Derived from an Intronless Transcript gene set www.pathwaycomm...
Null HIV Life Cycle View Gene Set 5.265e-07 103 5.795e-06 101 REACTOME - HIV Life Cycle gene set www.pathwaycomm...
Null Transport of Ribonucleoproteins into the Host Nucleus View Gene Set 5.292e-07 29 5.795e-06 101 REACTOME - Transport of Ribonucleoproteins into the Host Nucleus gene set www.pathwaycomm...
Null Ribosomal scanning and start codon recognition View Gene Set 5.94e-07 56 6.41e-06 103 REACTOME - Ribosomal scanning and start codon recognition gene set www.pathwaycomm...
Null Activation of the mRNA upon binding of the cap-binding complex and eIFs and subsequent binding to 43S View Gene Set 5.968e-07 57 6.41e-06 103 REACTOME - Activation of the mRNA upon binding of the cap-binding complex and eIFs and subsequent binding to 43S gene set www.pathwaycomm... and subsequent ...
Null Late Phase of HIV Life Cycle View Gene Set 6.301e-07 92 6.676e-06 105 REACTOME - Late Phase of HIV Life Cycle gene set www.pathwaycomm...
Null Regulation of gene expression in beta cells View Gene Set 6.336e-07 100 6.676e-06 105 REACTOME - Regulation of gene expression in beta cells gene set www.pathwaycomm...
Null Translation initiation complex formation View Gene Set 8.653e-07 56 9.033e-06 107 REACTOME - Translation initiation complex formation gene set www.pathwaycomm...
Null Regulation of beta-cell development View Gene Set 9.869e-07 110 1.021e-05 108 REACTOME - Regulation of beta-cell development gene set www.pathwaycomm...
Null Cytosolic tRNA aminoacylation View Gene Set 1.319e-06 24 1.352e-05 109 REACTOME - Cytosolic tRNA aminoacylation gene set www.pathwaycomm...
Null Deadenylation-dependent mRNA decay View Gene Set 1.342e-06 46 1.362e-05 110 REACTOME - Deadenylation-dependent mRNA decay gene set www.pathwaycomm...
Null Cyclin A:Cdk2-associated events at S phase entry View Gene Set 1.775e-06 62 1.787e-05 111 REACTOME - Cyclin A:Cdk2-associated events at S phase entry gene set www.pathwaycomm...
Null Prefoldin mediated transfer of substrate to CCT/TriC View Gene Set 4.875e-06 14 4.862e-05 112 REACTOME - Prefoldin mediated transfer of substrate to CCT/TriC gene set www.pathwaycomm...
Null Cyclin E associated events during G1/S transition View Gene Set 5.717e-06 64 5.651e-05 113 REACTOME - Cyclin E associated events during G1/S transition gene set www.pathwaycomm...
Null Vpr-mediated nuclear import of PICs View Gene Set 7.487e-06 31 7.336e-05 114 REACTOME - Vpr-mediated nuclear import of PICs gene set www.pathwaycomm...
Null DNA strand elongation View Gene Set 1.221e-05 31 0.0001186 115 REACTOME - DNA strand elongation gene set www.pathwaycomm...
Null Interactions of Vpr with host cellular proteins View Gene Set 1.473e-05 34 0.0001418 116 REACTOME - Interactions of Vpr with host cellular proteins gene set www.pathwaycomm...
Null Phosphorylation of Emi1 View Gene Set 1.489e-05 12 0.0001421 117 REACTOME - Phosphorylation of Emi1 gene set www.pathwaycomm...
Null Deposition of New CENPA-containing Nucleosomes at the Centromere View Gene Set 1.808e-05 35 0.0001697 118 REACTOME - Deposition of New CENPA-containing Nucleosomes at the Centromere gene set www.pathwaycomm...
Null Nucleosome assembly View Gene Set 1.808e-05 35 0.0001697 118 REACTOME - Nucleosome assembly gene set www.pathwaycomm...
Null Recruitment of NuMA to mitotic centrosomes View Gene Set 2.178e-05 14 0.0002027 120 REACTOME - Recruitment of NuMA to mitotic centrosomes gene set www.pathwaycomm...
Null Regulation of Glucokinase by Glucokinase Regulatory Protein View Gene Set 2.338e-05 29 0.0002158 121 REACTOME - Regulation of Glucokinase by Glucokinase Regulatory Protein gene set www.pathwaycomm...
Null Homologous Recombination Repair View Gene Set 2.793e-05 22 0.0002536 122 REACTOME - Homologous Recombination Repair gene set www.pathwaycomm...
Null Homologous recombination repair of replication-independent double-strand breaks View Gene Set 2.793e-05 22 0.0002536 122 REACTOME - Homologous recombination repair of replication-independent double-strand breaks gene set www.pathwaycomm...
Null Mitotic G2-G2/M phases View Gene Set 2.918e-05 98 0.0002628 124 REACTOME - Mitotic G2-G2/M phases gene set www.pathwaycomm...
Null Pyrimidine biosynthesis View Gene Set 3.072e-05 6 0.0002745 125 REACTOME - Pyrimidine biosynthesis gene set www.pathwaycomm...
Null Formation of tubulin folding intermediates by CCT/TriC View Gene Set 3.166e-05 8 0.0002807 126 REACTOME - Formation of tubulin folding intermediates by CCT/TriC gene set www.pathwaycomm...
Null Post-Elongation Processing of Intronless pre-mRNA View Gene Set 3.527e-05 23 0.0003058 127 REACTOME - Post-Elongation Processing of Intronless pre-mRNA gene set www.pathwaycomm...
Null Processing of Capped Intronless Pre-mRNA View Gene Set 3.527e-05 23 0.0003058 127 REACTOME - Processing of Capped Intronless Pre-mRNA gene set www.pathwaycomm...
Null Extension of Telomeres View Gene Set 3.532e-05 28 0.0003058 127 REACTOME - Extension of Telomeres gene set www.pathwaycomm...
Null Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding View Gene Set 3.694e-05 15 0.0003174 130 REACTOME - Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding gene set www.pathwaycomm...
Null Formation of the ternary complex and subsequently the 43S complex View Gene Set 4.131e-05 49 0.0003522 131 REACTOME - Formation of the ternary complex and subsequently the 43S complex gene set www.pathwaycomm... and subsequentl... the 43S complex...
Null Metabolism of amino acids and derivatives View Gene Set 4.723e-05 201 0.0003988 132 REACTOME - Metabolism of amino acids and derivatives gene set www.pathwaycomm...
Null Mitotic Telophase /Cytokinesis View Gene Set 4.749e-05 10 0.0003988 132 REACTOME - Mitotic Telophase /Cytokinesis gene set www.pathwaycomm...
Null Glucose transport View Gene Set 5.538e-05 38 0.0004597 134 REACTOME - Glucose transport gene set www.pathwaycomm...
Null Metabolism of nucleotides View Gene Set 5.555e-05 66 0.0004597 134 REACTOME - Metabolism of nucleotides gene set www.pathwaycomm...
Null DNA Repair View Gene Set 5.874e-05 108 0.0004824 136 REACTOME - DNA Repair gene set www.pathwaycomm...
Null Unwinding of DNA View Gene Set 6.284e-05 11 0.0005123 137 REACTOME - Unwinding of DNA gene set www.pathwaycomm...
Null Double-Strand Break Repair View Gene Set 6.825e-05 27 0.0005524 138 REACTOME - Double-Strand Break Repair gene set www.pathwaycomm...
Null Phosphorylation of the APC/C View Gene Set 7.161e-05 26 0.0005755 139 REACTOME - Phosphorylation of the APC/C gene set www.pathwaycomm...
Null Recruitment of repair and signaling proteins to double-strand breaks View Gene Set 7.394e-05 8 0.0005899 140 REACTOME - Recruitment of repair and signaling proteins to double-strand breaks gene set www.pathwaycomm...
Null G2/M Transition View Gene Set 7.46e-05 96 0.000591 141 REACTOME - G2/M Transition gene set www.pathwaycomm...
Null Chaperonin-mediated protein folding View Gene Set 7.911e-05 16 0.0006223 142 REACTOME - Chaperonin-mediated protein folding gene set www.pathwaycomm...
Null Purine ribonucleoside monophosphate biosynthesis View Gene Set 8.552e-05 7 0.000668 143 REACTOME - Purine ribonucleoside monophosphate biosynthesis gene set www.pathwaycomm...
Null Polo-like kinase mediated events View Gene Set 8.976e-05 10 0.0006963 144 REACTOME - Polo-like kinase mediated events gene set www.pathwaycomm...
Null Association of TriC/CCT with target proteins during biosynthesis View Gene Set 0.0001114 9 0.0008585 145 REACTOME - Association of TriC/CCT with target proteins during biosynthesis gene set www.pathwaycomm...
Null E2F mediated regulation of DNA replication View Gene Set 0.0001527 28 0.001169 146 REACTOME - E2F mediated regulation of DNA replication gene set www.pathwaycomm...
Null ATM mediated phosphorylation of repair proteins View Gene Set 0.0001572 6 0.001187 147 REACTOME - ATM mediated phosphorylation of repair proteins gene set www.pathwaycomm...
Null ATM mediated response to DNA double-strand break View Gene Set 0.0001572 6 0.001187 147 REACTOME - ATM mediated response to DNA double-strand break gene set www.pathwaycomm...
Null Meiotic Recombination View Gene Set 0.0001918 42 0.001438 149 REACTOME - Meiotic Recombination gene set www.pathwaycomm...
Null CDC6 association with the ORC:origin complex View Gene Set 0.0002057 11 0.001532 150 REACTOME - CDC6 association with the ORC:origin complex gene set www.pathwaycomm...
Null Hexose transport View Gene Set 0.0002813 40 0.002081 151 REACTOME - Hexose transport gene set www.pathwaycomm...
Null Olfactory Signaling Pathway View Gene Set 0.0003334 370 0.00245 152 REACTOME - Olfactory Signaling Pathway gene set www.pathwaycomm...
Null Metabolism of proteins View Gene Set 0.0003495 263 0.002552 153 REACTOME - Metabolism of proteins gene set www.pathwaycomm...
Null Folding of actin by CCT/TriC View Gene Set 0.000373 9 0.002705 154 REACTOME - Folding of actin by CCT/TriC gene set www.pathwaycomm...
Null Telomere Maintenance View Gene Set 0.0003767 49 0.002715 155 REACTOME - Telomere Maintenance gene set www.pathwaycomm...
Null Centrosome maturation View Gene Set 0.0004378 73 0.003115 156 REACTOME - Centrosome maturation gene set www.pathwaycomm...
Null Recruitment of mitotic centrosome proteins and complexes View Gene Set 0.0004378 72 0.003115 156 REACTOME - Recruitment of mitotic centrosome proteins and complexes gene set www.pathwaycomm...
Null Synthesis Secretion and Inactivation of Glucagon-like Peptide-1 (GLP-1) View Gene Set 0.0004556 112 0.003221 158 REACTOME - Synthesis Secretion and Inactivation of Glucagon-like Peptide-1 (GLP-1) gene set www.pathwaycomm... Secretion... and Inactivatio...
Null SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs View Gene Set 0.0004724 11 0.003319 159 REACTOME - SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs gene set www.pathwaycomm...
Null Mitotic Metaphase/Anaphase Transition View Gene Set 0.0005368 8 0.003747 160 REACTOME - Mitotic Metaphase/Anaphase Transition gene set www.pathwaycomm...
Null Synthesis Secretion and Deacylation of Ghrelin View Gene Set 0.0005406 109 0.003751 161 REACTOME - Synthesis Secretion and Deacylation of Ghrelin gene set www.pathwaycomm... Secretion... and Deacylation...
Null Incretin Synthesis Secretion and Inactivation View Gene Set 0.0006347 115 0.004377 162 REACTOME - Incretin Synthesis Secretion and Inactivation gene set www.pathwaycomm... Secretion... and Inactivatio...
Null SLBP independent Processing of Histone Pre-mRNAs View Gene Set 0.0007638 10 0.005234 163 REACTOME - SLBP independent Processing of Histone Pre-mRNAs gene set www.pathwaycomm...
Null G1/S-Specific Transcription View Gene Set 0.0008326 16 0.005671 164 REACTOME - G1/S-Specific Transcription gene set www.pathwaycomm...
Null Synthesis Secretion and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) View Gene Set 0.0008796 107 0.005955 165 REACTOME - Synthesis Secretion and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) gene set www.pathwaycomm... Secretion... and Inactivatio...
Null Deadenylation of mRNA View Gene Set 0.00107 22 0.007201 166 REACTOME - Deadenylation of mRNA gene set www.pathwaycomm...
Null Telomere Extension By Telomerase View Gene Set 0.001224 6 0.008187 167 REACTOME - Telomere Extension By Telomerase gene set www.pathwaycomm...
Null Apoptosis View Gene Set 0.001659 148 0.01103 168 REACTOME - Apoptosis gene set www.pathwaycomm...
Null mTORC1-mediated signalling View Gene Set 0.001929 11 0.01275 169 REACTOME - mTORC1-mediated signalling gene set www.pathwaycomm...
Null Telomere C-strand (Lagging Strand) Synthesis View Gene Set 0.002051 22 0.01348 170 REACTOME - Telomere C-strand (Lagging Strand) Synthesis gene set www.pathwaycomm...
Null mRNA Decay by 3' to 5' Exoribonuclease View Gene Set 0.002461 11 0.01607 171 REACTOME - mRNA Decay by 3' to 5' Exoribonuclease gene set www.pathwaycomm...
Null Kinesins View Gene Set 0.002671 22 0.01735 172 REACTOME - Kinesins gene set www.pathwaycomm...
Null MRN complex relocalizes to nuclear foci View Gene Set 0.002754 4 0.01768 173 REACTOME - MRN complex relocalizes to nuclear foci gene set www.pathwaycomm...
Null Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks View Gene Set 0.002754 4 0.01768 173 REACTOME - Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks gene set www.pathwaycomm...
Null S6K1-mediated signalling View Gene Set 0.002939 9 0.01876 175 REACTOME - S6K1-mediated signalling gene set www.pathwaycomm...
Null Metabolism of carbohydrates View Gene Set 0.003731 93 0.02368 176 REACTOME - Metabolism of carbohydrates gene set www.pathwaycomm...
Null Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components View Gene Set 0.003947 18 0.02477 177 REACTOME - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components gene set www.pathwaycomm...
Null Inactivation of APC/C via direct inhibition of the APC/C complex View Gene Set 0.003947 18 0.02477 177 REACTOME - Inactivation of APC/C via direct inhibition of the APC/C complex gene set www.pathwaycomm...
Null NS1 Mediated Effects on Host Pathways View Gene Set 0.003973 3 0.02479 179 REACTOME - NS1 Mediated Effects on Host Pathways gene set www.pathwaycomm...
Null Processing of Intronless Pre-mRNAs View Gene Set 0.004366 14 0.02709 180 REACTOME - Processing of Intronless Pre-mRNAs gene set www.pathwaycomm...
Null Mitotic Spindle Checkpoint View Gene Set 0.004553 19 0.0281 181 REACTOME - Mitotic Spindle Checkpoint gene set www.pathwaycomm...
Null Mitochondrial transcription initiation View Gene Set 0.004656 3 0.02845 182 REACTOME - Mitochondrial transcription initiation gene set www.pathwaycomm...
Null Insulin Synthesis and Processing View Gene Set 0.004661 132 0.02845 182 REACTOME - Insulin Synthesis and Processing gene set www.pathwaycomm...
Null Gap-filling DNA repair synthesis and ligation in TC-NER View Gene Set 0.004934 16 0.02979 184 REACTOME - Gap-filling DNA repair synthesis and ligation in TC-NER gene set www.pathwaycomm...
Null Gap-filling DNA repair synthesis and ligation in GG-NER View Gene Set 0.004934 16 0.02979 184 REACTOME - Gap-filling DNA repair synthesis and ligation in GG-NER gene set www.pathwaycomm...
Null E2F-enabled inhibition of pre-replication complex formation View Gene Set 0.005464 10 0.03281 186 REACTOME - E2F-enabled inhibition of pre-replication complex formation gene set www.pathwaycomm...
Null Nucleotide Excision Repair View Gene Set 0.006569 51 0.03924 187 REACTOME - Nucleotide Excision Repair gene set www.pathwaycomm...
Null Host Interactions with Influenza Factors View Gene Set 0.006732 5 0.04 188 REACTOME - Host Interactions with Influenza Factors gene set www.pathwaycomm...
Null Pyrimidine metabolism View Gene Set 0.007834 23 0.0463 189 REACTOME - Pyrimidine metabolism gene set www.pathwaycomm...

Gene Set Collection: mirbase.targets

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-383 View Gene Set 1.139e-06 748 0.00081 1 microRNA targets for hsa-miR-383 from mirbase.targets www.mirbase.org...

Gene Set Collection: hprdBatch.UP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null T Cell Receptor Signaling Pathway View Gene Set 0.001544 291 0.03089 1 From NetPath for T Cell Receptor Signaling Pathway www.netpath.org...