Results

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Go to: Gene Set Collection: KEGG
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Go to: Gene Set Collection: Broad.c1.CYTOBAND
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Go to: Gene Set Collection: Broad.c2.CP.BIOCARTA
Go to: Gene Set Collection: Broad.c2.CP.KEGG
Go to: Gene Set Collection: Broad.c2.CP.REACTOME
Go to: Gene Set Collection: Broad.c3.TFT
Go to: Gene Set Collection: Broad.c4.CGN
Go to: Gene Set Collection: Broad.c4.CM
Go to: Gene Set Collection: Broad.c5.BP
Go to: Gene Set Collection: Broad.c5.CC
Go to: Gene Set Collection: Broad.c5.MF
Go to: Gene Set Collection: PMID
Go to: Gene Set Collection: ChromosomalTiles5Mb
Go to: Gene Set Collection: Prosite
Go to: Gene Set Collection: Enzyme
Go to: Gene Set Collection: ppi.BIND
Go to: Gene Set Collection: ppi.BioGRID
Go to: Gene Set Collection: ppi.HPRD
Go to: Gene Set Collection: ppi.anyDB
Go to: Gene Set Collection: pathwayCommons.cell-map
Go to: Gene Set Collection: pathwayCommons.humancyc
Go to: Gene Set Collection: pathwayCommons.nci-nature
Go to: Gene Set Collection: pathwayCommons.reactome
Go to: Gene Set Collection: mirbase.targets
Go to: Gene Set Collection: tarbase.targets
Go to: Gene Set Collection: tfbsK3Z3

AFA results for: tVPAda4PC3

Click on the heading for any column to sort by that column.

Gene Set Collection: KEGG

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
KEGG 03040 View Gene Set 1.172e-24 128 2.509e-22 1 Spliceosome www.genome.jp/d...
KEGG 00970 View Gene Set 2.289e-14 41 2.45e-12 2 Aminoacyl-tRNA biosynthesis www.genome.jp/d...
KEGG 03018 View Gene Set 1.108e-07 59 7.906e-06 3 RNA degradation www.genome.jp/d...
KEGG 00240 View Gene Set 3.783e-07 99 1.619e-05 4 Pyrimidine metabolism www.genome.jp/d...
KEGG 03030 View Gene Set 3.255e-07 36 1.619e-05 4 DNA replication www.genome.jp/d...
KEGG 03410 View Gene Set 8.565e-07 34 3.055e-05 6 Base excision repair www.genome.jp/d...
KEGG 03050 View Gene Set 6.202e-06 48 0.0001896 7 Proteasome www.genome.jp/d...
KEGG 04110 View Gene Set 7.986e-06 128 0.0002136 8 Cell cycle www.genome.jp/d...
KEGG 00290 View Gene Set 2.335e-05 11 0.0005552 9 Valine leucine and isoleucine biosynthesis www.genome.jp/d...
KEGG 00310 View Gene Set 3.458e-05 46 0.0007401 10 Lysine degradation www.genome.jp/d...
KEGG 01100 View Gene Set 4.377e-05 1120 0.0008421 11 Metabolic pathways www.genome.jp/d...
KEGG 03430 View Gene Set 4.722e-05 23 0.0008421 11 Mismatch repair www.genome.jp/d...
KEGG 00020 View Gene Set 0.000117 31 0.001926 13 Citrate cycle (TCA cycle) www.genome.jp/d...
KEGG 00010 View Gene Set 0.000157 64 0.002239 14 Glycolysis / Gluconeogenesis www.genome.jp/d...
KEGG 03020 View Gene Set 0.0001509 29 0.002239 14 RNA polymerase www.genome.jp/d...
KEGG 00670 View Gene Set 0.0003094 17 0.004138 16 One carbon pool by folate www.genome.jp/d...
KEGG 05322 View Gene Set 0.000802 141 0.0101 17 Systemic lupus erythematosus www.genome.jp/d...
KEGG 00270 View Gene Set 0.000997 34 0.01185 18 Cysteine and methionine metabolism www.genome.jp/d...
KEGG 00620 View Gene Set 0.001065 40 0.01199 19 Pyruvate metabolism www.genome.jp/d...
KEGG 05012 View Gene Set 0.001598 132 0.0171 20 Parkinson's disease www.genome.jp/d...
KEGG 03420 View Gene Set 0.001732 44 0.01765 21 Nucleotide excision repair www.genome.jp/d...
KEGG 05016 View Gene Set 0.002843 184 0.02766 22 Huntington's disease www.genome.jp/d...

Gene Set Collection: GO

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
GO GO:0006396 View Gene Set 7.377e-81 578 9.856e-77 1 RNA processing amigo.geneontol...
GO GO:0044428 View Gene Set 4.321e-75 1938 2.886e-71 2 nuclear part amigo.geneontol...
GO GO:0031974 View Gene Set 5.061e-72 1917 2.254e-68 3 membrane-enclosed lumen amigo.geneontol...
GO GO:0070013 View Gene Set 2.655e-71 1845 8.869e-68 4 intracellular organelle lumen amigo.geneontol...
GO GO:0043233 View Gene Set 5.617e-70 1881 1.501e-66 5 organelle lumen amigo.geneontol...
GO GO:0003723 View Gene Set 3.188e-62 732 7.098e-59 6 RNA binding amigo.geneontol...
GO GO:0031981 View Gene Set 4.053e-58 1518 7.735e-55 7 nuclear lumen amigo.geneontol...
GO GO:0030529 View Gene Set 8.844e-51 504 1.477e-47 8 ribonucleoprotein complex amigo.geneontol...
GO GO:0008380 View Gene Set 7.078e-48 300 9.738e-45 9 RNA splicing amigo.geneontol...
GO GO:0003676 View Gene Set 7.289e-48 2979 9.738e-45 9 nucleic acid binding amigo.geneontol...
GO GO:0090304 View Gene Set 7.584e-47 3724 9.211e-44 11 nucleic acid metabolic process amigo.geneontol...
GO GO:0005634 View Gene Set 1.849e-46 5198 2.058e-43 12 nucleus amigo.geneontol...
GO GO:0010467 View Gene Set 7.819e-46 3806 8.036e-43 13 gene expression amigo.geneontol...
GO GO:0016071 View Gene Set 2.59e-45 381 2.472e-42 14 mRNA metabolic process amigo.geneontol...
GO GO:0034641 View Gene Set 4.192e-45 4584 3.734e-42 15 cellular nitrogen compound metabolic process amigo.geneontol...
GO GO:0044260 View Gene Set 1.036e-44 5699 8.65e-42 16 cellular macromolecule metabolic process amigo.geneontol...
GO GO:0006139 View Gene Set 3.677e-43 4294 2.889e-40 17 nucleobase nucleoside nucleotide and nucleic acid metabolic process amigo.geneontol...
GO GO:0006807 View Gene Set 9.892e-43 4698 7.342e-40 18 nitrogen compound metabolic process amigo.geneontol...
GO GO:0034660 View Gene Set 2.277e-42 236 1.601e-39 19 ncRNA metabolic process amigo.geneontol...
GO GO:0005654 View Gene Set 2.758e-42 939 1.842e-39 20 nucleoplasm amigo.geneontol...
GO GO:0043170 View Gene Set 9.34e-41 6274 5.942e-38 21 macromolecule metabolic process amigo.geneontol...
GO GO:0006397 View Gene Set 2.127e-40 317 1.292e-37 22 mRNA processing amigo.geneontol...
GO GO:0044237 View Gene Set 5.328e-38 7431 3.095e-35 23 cellular metabolic process amigo.geneontol...
GO GO:0022613 View Gene Set 1.099e-36 194 6.116e-34 24 ribonucleoprotein complex biogenesis amigo.geneontol...
GO GO:0044238 View Gene Set 2.61e-35 7629 1.395e-32 25 primary metabolic process amigo.geneontol...
GO GO:0008152 View Gene Set 4.301e-35 8439 2.21e-32 26 metabolic process amigo.geneontol...
GO GO:0005739 View Gene Set 7.787e-34 1274 3.853e-31 27 mitochondrion amigo.geneontol...
GO GO:0016070 View Gene Set 2.786e-33 2596 1.33e-30 28 RNA metabolic process amigo.geneontol...
GO GO:0034470 View Gene Set 2.073e-32 193 9.551e-30 29 ncRNA processing amigo.geneontol...
GO GO:0005730 View Gene Set 1.619e-29 734 7.209e-27 30 nucleolus amigo.geneontol...
GO GO:0006412 View Gene Set 9.571e-29 412 4.125e-26 31 translation amigo.geneontol...
GO GO:0044451 View Gene Set 1.837e-28 600 7.671e-26 32 nucleoplasm part amigo.geneontol...
GO GO:0032991 View Gene Set 2.536e-27 3237 1.027e-24 33 macromolecular complex amigo.geneontol...
GO GO:0005759 View Gene Set 4.004e-27 223 1.528e-24 34 mitochondrial matrix amigo.geneontol...
GO GO:0031980 View Gene Set 4.004e-27 223 1.528e-24 34 mitochondrial lumen amigo.geneontol...
GO GO:0006399 View Gene Set 6.998e-27 118 2.597e-24 36 tRNA metabolic process amigo.geneontol...
GO GO:0005681 View Gene Set 1.435e-26 135 5.181e-24 37 spliceosomal complex amigo.geneontol...
GO GO:0000375 View Gene Set 1.719e-26 106 6.042e-24 38 RNA splicing via transesterification reactions amigo.geneontol...
GO GO:0043227 View Gene Set 6.07e-26 8383 2.079e-23 39 membrane-bounded organelle amigo.geneontol...
GO GO:0000166 View Gene Set 9.168e-26 2257 3.062e-23 40 nucleotide binding amigo.geneontol...
GO GO:0043231 View Gene Set 1.01e-25 8376 3.291e-23 41 intracellular membrane-bounded organelle amigo.geneontol...
GO GO:0044429 View Gene Set 2.031e-25 619 6.461e-23 42 mitochondrial part amigo.geneontol...
GO GO:0000377 View Gene Set 2.314e-24 97 7.027e-22 43 RNA splicing via transesterification reactions with bulged adenosine as nucleophile amigo.geneontol...
GO GO:0000398 View Gene Set 2.314e-24 97 7.027e-22 43 nuclear mRNA splicing via spliceosome amigo.geneontol...
GO GO:0042254 View Gene Set 1.05e-21 130 3.116e-19 45 ribosome biogenesis amigo.geneontol...
GO GO:0005694 View Gene Set 2.737e-21 507 7.949e-19 46 chromosome amigo.geneontol...
GO GO:0044446 View Gene Set 2.736e-20 5019 7.777e-18 47 intracellular organelle part amigo.geneontol...
GO GO:0006403 View Gene Set 3.08e-20 104 8.573e-18 48 RNA localization amigo.geneontol...
GO GO:0044249 View Gene Set 4.204e-20 4326 1.146e-17 49 cellular biosynthetic process amigo.geneontol...
GO GO:0050657 View Gene Set 1.349e-19 102 3.466e-17 50 nucleic acid transport amigo.geneontol...
GO GO:0050658 View Gene Set 1.349e-19 102 3.466e-17 50 RNA transport amigo.geneontol...
GO GO:0051236 View Gene Set 1.349e-19 102 3.466e-17 50 establishment of RNA localization amigo.geneontol...
GO GO:0009058 View Gene Set 1.845e-19 4436 4.651e-17 53 biosynthetic process amigo.geneontol...
GO GO:0005524 View Gene Set 5.375e-19 1480 1.33e-16 54 ATP binding amigo.geneontol...
GO GO:0030554 View Gene Set 5.627e-19 1584 1.367e-16 55 adenyl nucleotide binding amigo.geneontol...
GO GO:0032559 View Gene Set 6.474e-19 1503 1.544e-16 56 adenyl ribonucleotide binding amigo.geneontol...
GO GO:0022618 View Gene Set 1.225e-18 76 2.872e-16 57 ribonucleoprotein complex assembly amigo.geneontol...
GO GO:0044422 View Gene Set 1.316e-18 5089 3.031e-16 58 organelle part amigo.geneontol...
GO GO:0006259 View Gene Set 2.569e-18 592 5.818e-16 59 DNA metabolic process amigo.geneontol...
GO GO:0015931 View Gene Set 6.26e-18 118 1.394e-15 60 nucleobase nucleoside nucleotide and nucleic acid transport amigo.geneontol...
GO GO:0001882 View Gene Set 1.719e-17 1630 3.765e-15 61 nucleoside binding amigo.geneontol...
GO GO:0001883 View Gene Set 2.639e-17 1620 5.687e-15 62 purine nucleoside binding amigo.geneontol...
GO GO:0016604 View Gene Set 3.491e-17 198 7.403e-15 63 nuclear body amigo.geneontol...
GO GO:0044427 View Gene Set 4.405e-17 420 9.196e-15 64 chromosomal part amigo.geneontol...
GO GO:0034645 View Gene Set 4.581e-17 3529 9.416e-15 65 cellular macromolecule biosynthetic process amigo.geneontol...
GO GO:0009059 View Gene Set 5.945e-17 3597 1.203e-14 66 macromolecule biosynthetic process amigo.geneontol...
GO GO:0051028 View Gene Set 9.46e-17 90 1.886e-14 67 mRNA transport amigo.geneontol...
GO GO:0051276 View Gene Set 1.093e-16 548 2.147e-14 68 chromosome organization amigo.geneontol...
GO GO:0043226 View Gene Set 3.479e-16 9360 6.736e-14 69 organelle amigo.geneontol...
GO GO:0043229 View Gene Set 3.59e-16 9346 6.852e-14 70 intracellular organelle amigo.geneontol...
GO GO:0016072 View Gene Set 3.913e-16 101 7.363e-14 71 rRNA metabolic process amigo.geneontol...
GO GO:0043228 View Gene Set 5.302e-16 2690 9.704e-14 72 non-membrane-bounded organelle amigo.geneontol...
GO GO:0043232 View Gene Set 5.302e-16 2690 9.704e-14 72 intracellular non-membrane-bounded organelle amigo.geneontol...
GO GO:0031967 View Gene Set 8.823e-16 672 1.593e-13 74 organelle envelope amigo.geneontol...
GO GO:0008033 View Gene Set 1.118e-15 78 1.992e-13 75 tRNA processing amigo.geneontol...
GO GO:0005840 View Gene Set 1.431e-15 198 2.515e-13 76 ribosome amigo.geneontol...
GO GO:0006364 View Gene Set 2.321e-15 97 4.027e-13 77 rRNA processing amigo.geneontol...
GO GO:0004812 View Gene Set 6.923e-15 46 1.156e-12 78 aminoacyl-tRNA ligase activity amigo.geneontol...
GO GO:0016875 View Gene Set 6.923e-15 46 1.156e-12 78 ligase activity forming carbon-oxygen bonds amigo.geneontol...
GO GO:0016876 View Gene Set 6.923e-15 46 1.156e-12 78 ligase activity forming aminoacyl-tRNA and related compounds amigo.geneontol...
GO GO:0044424 View Gene Set 8.762e-15 10976 1.445e-12 81 intracellular part amigo.geneontol...
GO GO:0000313 View Gene Set 1.182e-14 49 1.903e-12 82 organellar ribosome amigo.geneontol...
GO GO:0005761 View Gene Set 1.182e-14 49 1.903e-12 82 mitochondrial ribosome amigo.geneontol...
GO GO:0003824 View Gene Set 1.325e-14 5198 2.107e-12 84 catalytic activity amigo.geneontol...
GO GO:0006418 View Gene Set 1.461e-14 45 2.244e-12 85 tRNA aminoacylation for protein translation amigo.geneontol...
GO GO:0043038 View Gene Set 1.461e-14 45 2.244e-12 85 amino acid activation amigo.geneontol...
GO GO:0043039 View Gene Set 1.461e-14 45 2.244e-12 85 tRNA aminoacylation amigo.geneontol...
GO GO:0031975 View Gene Set 2.01e-14 685 3.051e-12 88 envelope amigo.geneontol...
GO GO:0000278 View Gene Set 2.25e-14 489 3.378e-12 89 mitotic cell cycle amigo.geneontol...
GO GO:0004386 View Gene Set 4.07e-14 144 6.042e-12 90 helicase activity amigo.geneontol...
GO GO:0022402 View Gene Set 1.542e-13 676 2.265e-11 91 cell cycle process amigo.geneontol...
GO GO:0006260 View Gene Set 2.253e-13 239 3.272e-11 92 DNA replication amigo.geneontol...
GO GO:0006974 View Gene Set 2.967e-13 412 4.263e-11 93 response to DNA damage stimulus amigo.geneontol...
GO GO:0032553 View Gene Set 3.45e-13 1851 4.851e-11 94 ribonucleotide binding amigo.geneontol...
GO GO:0032555 View Gene Set 3.45e-13 1851 4.851e-11 94 purine ribonucleotide binding amigo.geneontol...
GO GO:0017076 View Gene Set 3.59e-13 1934 4.996e-11 96 purine nucleotide binding amigo.geneontol...
GO GO:0005622 View Gene Set 6.511e-13 11329 8.967e-11 97 intracellular amigo.geneontol...
GO GO:0008135 View Gene Set 1.201e-12 86 1.637e-10 98 translation factor activity nucleic acid binding amigo.geneontol...
GO GO:0016741 View Gene Set 1.392e-12 179 1.878e-10 99 transferase activity transferring one-carbon groups amigo.geneontol...
GO GO:0008168 View Gene Set 2.31e-12 176 3.087e-10 100 methyltransferase activity amigo.geneontol...
GO GO:0006281 View Gene Set 4.057e-12 309 5.367e-10 101 DNA repair amigo.geneontol...
GO GO:0008026 View Gene Set 5.155e-12 105 6.686e-10 102 ATP-dependent helicase activity amigo.geneontol...
GO GO:0070035 View Gene Set 5.155e-12 105 6.686e-10 102 purine NTP-dependent helicase activity amigo.geneontol...
GO GO:0006325 View Gene Set 7.185e-12 425 9.23e-10 104 chromatin organization amigo.geneontol...
GO GO:0000279 View Gene Set 8.429e-12 406 1.062e-09 105 M phase amigo.geneontol...
GO GO:0016607 View Gene Set 8.376e-12 116 1.062e-09 105 nuclear speck amigo.geneontol...
GO GO:0022403 View Gene Set 1.036e-11 522 1.293e-09 107 cell cycle phase amigo.geneontol...
GO GO:0019866 View Gene Set 1.282e-11 334 1.586e-09 108 organelle inner membrane amigo.geneontol...
GO GO:0003735 View Gene Set 1.342e-11 158 1.644e-09 109 structural constituent of ribosome amigo.geneontol...
GO GO:0005740 View Gene Set 2.106e-11 444 2.558e-09 110 mitochondrial envelope amigo.geneontol...
GO GO:0046930 View Gene Set 2.234e-11 85 2.689e-09 111 pore complex amigo.geneontol...
GO GO:0048285 View Gene Set 2.798e-11 286 3.337e-09 112 organelle fission amigo.geneontol...
GO GO:0071103 View Gene Set 3.045e-11 140 3.6e-09 113 DNA conformation change amigo.geneontol...
GO GO:0005743 View Gene Set 3.109e-11 305 3.644e-09 114 mitochondrial inner membrane amigo.geneontol...
GO GO:0000785 View Gene Set 3.229e-11 213 3.752e-09 115 chromatin amigo.geneontol...
GO GO:0006520 View Gene Set 3.458e-11 231 3.983e-09 116 cellular amino acid metabolic process amigo.geneontol...
GO GO:0005643 View Gene Set 4.615e-11 71 5.269e-09 117 nuclear pore amigo.geneontol...
GO GO:0044267 View Gene Set 7.053e-11 2465 7.985e-09 118 cellular protein metabolic process amigo.geneontol...
GO GO:0006261 View Gene Set 8.032e-11 74 9.017e-09 119 DNA-dependent DNA replication amigo.geneontol...
GO GO:0000280 View Gene Set 8.28e-11 276 9.142e-09 120 nuclear division amigo.geneontol...
GO GO:0007067 View Gene Set 8.28e-11 276 9.142e-09 120 mitosis amigo.geneontol...
GO GO:0000793 View Gene Set 9.998e-11 136 1.095e-08 122 condensed chromosome amigo.geneontol...
GO GO:0000387 View Gene Set 1.093e-10 31 1.187e-08 123 spliceosomal snRNP assembly amigo.geneontol...
GO GO:0006405 View Gene Set 1.186e-10 44 1.278e-08 124 RNA export from nucleus amigo.geneontol...
GO GO:0007049 View Gene Set 1.41e-10 1006 1.507e-08 125 cell cycle amigo.geneontol...
GO GO:0031966 View Gene Set 1.55e-10 420 1.644e-08 126 mitochondrial membrane amigo.geneontol...
GO GO:0016887 View Gene Set 2.602e-10 339 2.737e-08 127 ATPase activity amigo.geneontol...
GO GO:0000775 View Gene Set 3.923e-10 146 4.095e-08 128 chromosome centromeric region amigo.geneontol...
GO GO:0033279 View Gene Set 4.327e-10 121 4.482e-08 129 ribosomal subunit amigo.geneontol...
GO GO:0034621 View Gene Set 4.849e-10 458 4.983e-08 130 cellular macromolecular complex subunit organization amigo.geneontol...
GO GO:0044455 View Gene Set 4.899e-10 133 4.997e-08 131 mitochondrial membrane part amigo.geneontol...
GO GO:0000087 View Gene Set 5.65e-10 286 5.719e-08 132 M phase of mitotic cell cycle amigo.geneontol...
GO GO:0000245 View Gene Set 1.061e-09 34 1.065e-07 133 spliceosome assembly amigo.geneontol...
GO GO:0000228 View Gene Set 1.19e-09 177 1.187e-07 134 nuclear chromosome amigo.geneontol...
GO GO:0016568 View Gene Set 2.847e-09 324 2.817e-07 135 chromatin modification amigo.geneontol...
GO GO:0006401 View Gene Set 2.881e-09 74 2.83e-07 136 RNA catabolic process amigo.geneontol...
GO GO:0003743 View Gene Set 4.128e-09 52 4.025e-07 137 translation initiation factor activity amigo.geneontol...
GO GO:0044085 View Gene Set 4.226e-09 1167 4.092e-07 138 cellular component biogenesis amigo.geneontol...
GO GO:0040029 View Gene Set 4.687e-09 95 4.505e-07 139 regulation of gene expression epigenetic amigo.geneontol...
GO GO:0000049 View Gene Set 5.215e-09 24 4.977e-07 140 tRNA binding amigo.geneontol...
GO GO:0016569 View Gene Set 1.271e-08 165 1.204e-06 141 covalent chromatin modification amigo.geneontol...
GO GO:0003697 View Gene Set 1.482e-08 58 1.394e-06 142 single-stranded DNA binding amigo.geneontol...
GO GO:0000502 View Gene Set 1.764e-08 63 1.648e-06 143 proteasome complex amigo.geneontol...
GO GO:0019538 View Gene Set 1.905e-08 2935 1.767e-06 144 protein metabolic process amigo.geneontol...
GO GO:0030532 View Gene Set 2.163e-08 32 1.993e-06 145 small nuclear ribonucleoprotein complex amigo.geneontol...
GO GO:0015030 View Gene Set 2.258e-08 43 2.066e-06 146 Cajal body amigo.geneontol...
GO GO:0003677 View Gene Set 2.275e-08 2028 2.068e-06 147 DNA binding amigo.geneontol...
GO GO:0010605 View Gene Set 2.339e-08 827 2.111e-06 148 negative regulation of macromolecule metabolic process amigo.geneontol...
GO GO:0009451 View Gene Set 2.409e-08 51 2.16e-06 149 RNA modification amigo.geneontol...
GO GO:0044106 View Gene Set 2.916e-08 314 2.597e-06 150 cellular amine metabolic process amigo.geneontol...
GO GO:0000779 View Gene Set 3.878e-08 79 3.431e-06 151 condensed chromosome centromeric region amigo.geneontol...
GO GO:0034622 View Gene Set 4.214e-08 393 3.704e-06 152 cellular macromolecular complex assembly amigo.geneontol...
GO GO:0006406 View Gene Set 4.489e-08 34 3.92e-06 153 mRNA export from nucleus amigo.geneontol...
GO GO:0006333 View Gene Set 5.29e-08 129 4.589e-06 154 chromatin assembly or disassembly amigo.geneontol...
GO GO:0016570 View Gene Set 5.49e-08 162 4.732e-06 155 histone modification amigo.geneontol...
GO GO:0000776 View Gene Set 6.811e-08 92 5.833e-06 156 kinetochore amigo.geneontol...
GO GO:0051437 View Gene Set 7.165e-08 64 6.097e-06 157 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0060255 View Gene Set 7.612e-08 3411 6.396e-06 158 regulation of macromolecule metabolic process amigo.geneontol...
GO GO:0005488 View Gene Set 7.586e-08 12334 6.396e-06 158 binding amigo.geneontol...
GO GO:0009295 View Gene Set 7.919e-08 31 6.572e-06 160 nucleoid amigo.geneontol...
GO GO:0042645 View Gene Set 7.919e-08 31 6.572e-06 160 mitochondrial nucleoid amigo.geneontol...
GO GO:0007051 View Gene Set 8.516e-08 57 7.023e-06 162 spindle organization amigo.geneontol...
GO GO:0043566 View Gene Set 8.763e-08 149 7.182e-06 163 structure-specific DNA binding amigo.geneontol...
GO GO:0032392 View Gene Set 9.721e-08 19 7.823e-06 164 DNA geometric change amigo.geneontol...
GO GO:0032508 View Gene Set 9.721e-08 19 7.823e-06 164 DNA duplex unwinding amigo.geneontol...
GO GO:0045333 View Gene Set 9.646e-08 100 7.823e-06 164 cellular respiration amigo.geneontol...
GO GO:0009892 View Gene Set 1.059e-07 889 8.472e-06 167 negative regulation of metabolic process amigo.geneontol...
GO GO:0010608 View Gene Set 1.209e-07 247 9.616e-06 168 posttranscriptional regulation of gene expression amigo.geneontol...
GO GO:0044265 View Gene Set 1.26e-07 479 9.963e-06 169 cellular macromolecule catabolic process amigo.geneontol...
GO GO:0000777 View Gene Set 1.647e-07 74 1.295e-05 170 condensed chromosome kinetochore amigo.geneontol...
GO GO:0000315 View Gene Set 1.691e-07 18 1.314e-05 171 organellar large ribosomal subunit amigo.geneontol...
GO GO:0005762 View Gene Set 1.691e-07 18 1.314e-05 171 mitochondrial large ribosomal subunit amigo.geneontol...
GO GO:0031145 View Gene Set 1.768e-07 64 1.366e-05 173 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process amigo.geneontol...
GO GO:0044454 View Gene Set 1.843e-07 139 1.415e-05 174 nuclear chromosome part amigo.geneontol...
GO GO:0030880 View Gene Set 1.931e-07 25 1.474e-05 175 RNA polymerase complex amigo.geneontol...
GO GO:0043933 View Gene Set 2.059e-07 836 1.563e-05 176 macromolecular complex subunit organization amigo.geneontol...
GO GO:0051436 View Gene Set 2.35e-07 62 1.774e-05 177 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0004518 View Gene Set 2.476e-07 161 1.859e-05 178 nuclease activity amigo.geneontol...
GO GO:0051439 View Gene Set 2.617e-07 68 1.954e-05 179 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle amigo.geneontol...
GO GO:0006732 View Gene Set 2.659e-07 164 1.974e-05 180 coenzyme metabolic process amigo.geneontol...
GO GO:0051352 View Gene Set 2.809e-07 66 2.062e-05 181 negative regulation of ligase activity amigo.geneontol...
GO GO:0051444 View Gene Set 2.809e-07 66 2.062e-05 181 negative regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0006473 View Gene Set 2.843e-07 61 2.076e-05 183 protein amino acid acetylation amigo.geneontol...
GO GO:0000184 View Gene Set 3.005e-07 30 2.182e-05 184 nuclear-transcribed mRNA catabolic process nonsense-mediated decay amigo.geneontol...
GO GO:0009987 View Gene Set 3.618e-07 11620 2.613e-05 185 cellular process amigo.geneontol...
GO GO:0043234 View Gene Set 3.939e-07 2680 2.829e-05 186 protein complex amigo.geneontol...
GO GO:0000428 View Gene Set 4.662e-07 24 3.313e-05 187 DNA-directed RNA polymerase complex amigo.geneontol...
GO GO:0055029 View Gene Set 4.662e-07 24 3.313e-05 187 nuclear DNA-directed RNA polymerase complex amigo.geneontol...
GO GO:0051168 View Gene Set 5.339e-07 71 3.774e-05 189 nuclear export amigo.geneontol...
GO GO:0006996 View Gene Set 5.933e-07 1501 4.171e-05 190 organelle organization amigo.geneontol...
GO GO:0051443 View Gene Set 6.8e-07 71 4.756e-05 191 positive regulation of ubiquitin-protein ligase activity amigo.geneontol...
GO GO:0003682 View Gene Set 7.08e-07 178 4.927e-05 192 chromatin binding amigo.geneontol...
GO GO:0005819 View Gene Set 7.174e-07 167 4.966e-05 193 spindle amigo.geneontol...
GO GO:0016740 View Gene Set 7.487e-07 1691 5.156e-05 194 transferase activity amigo.geneontol...
GO GO:0000314 View Gene Set 8.329e-07 18 5.678e-05 195 organellar small ribosomal subunit amigo.geneontol...
GO GO:0005763 View Gene Set 8.329e-07 18 5.678e-05 195 mitochondrial small ribosomal subunit amigo.geneontol...
GO GO:0006519 View Gene Set 8.775e-07 371 5.951e-05 197 cellular amino acid and derivative metabolic process amigo.geneontol...
GO GO:0051351 View Gene Set 8.837e-07 74 5.963e-05 198 positive regulation of ligase activity amigo.geneontol...
GO GO:0030530 View Gene Set 8.906e-07 17 5.979e-05 199 heterogeneous nuclear ribonucleoprotein complex amigo.geneontol...
GO GO:0007059 View Gene Set 9.63e-07 94 6.433e-05 200 chromosome segregation amigo.geneontol...

Gene Set Collection: Broad.c1.CYTOBAND

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad chr22q13 View Gene Set 1.716e-06 179 0.0005594 1 Genes in cytogenetic band chr22q13 www.broad.mit.e...
Broad chr6p22 View Gene Set 4.161e-05 137 0.006783 2 Genes in cytogenetic band chr6p22 www.broad.mit.e...
Broad chr5q12 View Gene Set 7.022e-05 45 0.007631 3 Genes in cytogenetic band chr5q12 www.broad.mit.e...
Broad chr9q34 View Gene Set 0.0004489 204 0.03659 4 Genes in cytogenetic band chr9q34 www.broad.mit.e...

Gene Set Collection: Broad.c2.CGP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad PUJANA_CHEK2_PCC_NETWORK View Gene Set 1.957e-77 744 4.68e-74 1 Genes constituting the CHEK2-PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient PCC >= 0.4) with that of CHEK2 [Gene ID=11200]. www.broad.mit.e...
Broad PUJANA_BRCA1_PCC_NETWORK View Gene Set 4.254e-76 1582 5.088e-73 2 Genes constituting the BRCA1-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA1 [Gene ID=672] across a compendium of normal tissues. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN View Gene Set 9.343e-68 920 7.45e-65 3 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h. www.broad.mit.e...
Broad CAIRO_HEPATOBLASTOMA_CLASSES_UP View Gene Set 6.399e-65 577 3.827e-62 4 Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). www.broad.mit.e...
Broad MANALO_HYPOXIA_DN View Gene Set 7.51e-61 276 3.593e-58 5 Genes down-regulated in response to both hypoxia and overexpression of an active form of HIF1A [Gene ID=3091]. www.broad.mit.e...
Broad DODD_NASOPHARYNGEAL_CARCINOMA_DN View Gene Set 1.413e-49 1253 5.632e-47 6 Genes down-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN View Gene Set 2.396e-45 832 8.186e-43 7 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. www.broad.mit.e...
Broad WONG_EMBRYONIC_STEM_CELL_CORE View Gene Set 1.045e-42 331 3.124e-40 8 The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module. www.broad.mit.e...
Broad KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP View Gene Set 1.146e-39 1180 3.045e-37 9 Genes up-regulated in TC71 and EWS502 cells (Ewing's sarcoma) upon knockdown of the EWSR1-FLII fusion [Gene ID=2130 2314]. www.broad.mit.e...
Broad WEI_MYCN_TARGETS_WITH_E_BOX View Gene Set 3.678e-36 757 8.798e-34 10 Genes whose promoters contain E-box motifs and whose expression changed in MYCN-3 cells (neuroblastoma) upon induction of MYCN [Gene ID=4613]. www.broad.mit.e...
Broad PUJANA_BRCA2_PCC_NETWORK View Gene Set 1.114e-29 410 2.421e-27 11 Genes constituting the BRCA2-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA2 [Gene ID=675] across a compendium of normal tissues. www.broad.mit.e...
Broad MUELLER_PLURINET View Gene Set 1.371e-27 294 2.733e-25 12 Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells embryonical carcinomas and induced pluripotent cells). www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM View Gene Set 3.015e-26 154 5.548e-24 13 Cluster 7: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] and down-regulated by the combination of MYC and serum. www.broad.mit.e...
Broad MOOTHA_HUMAN_MITODB_6_2002 View Gene Set 1.488e-23 420 2.543e-21 14 Mitochondrial genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. www.broad.mit.e...
Broad MOOTHA_MITOCHONDRIA View Gene Set 2.242e-23 433 3.575e-21 15 Mitochondrial genes www.broad.mit.e...
Broad CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN View Gene Set 9.659e-23 639 1.444e-20 16 Genes down-regulated in APL (acute promyeolocytic leukemia) blasts expressing PML-RARA fusion [Gene ID=5371 5914] compared to normal promyeloblasts. www.broad.mit.e...
Broad GARY_CD5_TARGETS_DN View Gene Set 4.394e-22 415 6.182e-20 17 Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. www.broad.mit.e...
Broad PUJANA_XPRSS_INT_NETWORK View Gene Set 1.054e-19 164 1.4e-17 18 Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200] in a compendium of normal tissues. www.broad.mit.e...
Broad WELCSH_BRCA1_TARGETS_1_DN View Gene Set 2.405e-18 124 3.028e-16 19 Upregulated by induction of exogenous BRCA1 in EcR-293 cells www.broad.mit.e...
Broad BERENJENO_TRANSFORMED_BY_RHOA_UP View Gene Set 3.282e-18 485 3.925e-16 20 Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [Gene ID=387] off plasmid vector. www.broad.mit.e...
Broad TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C View Gene Set 6.514e-18 436 7.42e-16 21 Genes down-regulated in HCT116 cells (colon cancer) upon expression of MIR34B or MIR34C [Gene ID=407041 407042] microRNAs. www.broad.mit.e...
Broad PUJANA_ATM_PCC_NETWORK View Gene Set 9.728e-18 1375 1.058e-15 22 Genes constituting the ATM-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of ATM [Gene ID=472] across a compendium of normal tissues. www.broad.mit.e...
Broad TARTE_PLASMA_CELL_VS_PLASMABLAST_DN View Gene Set 1.061e-17 303 1.104e-15 23 Genes down-regulated in mature plasma cells compared with plasmablastic B lymphocytes. www.broad.mit.e...
Broad CROONQUIST_IL6_DEPRIVATION_DN View Gene Set 1.951e-17 80 1.945e-15 24 Genes down-regulated in the ANBL-6 cell line (multiple myeloma MM) after withdrawal of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad GRADE_COLON_CANCER_UP View Gene Set 3.259e-17 711 3.118e-15 25 Up-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples. www.broad.mit.e...
Broad CROONQUIST_NRAS_SIGNALING_DN View Gene Set 6.326e-17 62 5.82e-15 26 Genes down-regulated in ANBL-6 cell line (multiple myeloma MM) expressing a constantly active form of NRAS [Gene ID=4893] off a plasmid vector compared to those grown in the presence of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad DANG_MYC_TARGETS_UP View Gene Set 2.93e-16 127 2.595e-14 27 Genes up-regulated by MYC [Gene ID=4609] and whose promoters are bound by MYC according to MYC Target Gene Database. www.broad.mit.e...
Broad PUJANA_BRCA_CENTERED_NETWORK View Gene Set 3.305e-16 92 2.823e-14 28 Genes constituting the BRCA-centered network (BCN). www.broad.mit.e...
Broad DANG_BOUND_BY_MYC View Gene Set 5.02e-16 1045 4.141e-14 29 Genes whose promoters are bound by MYC [Gene ID=4609] according to MYC Target Gene Database. www.broad.mit.e...
Broad SCHUHMACHER_MYC_TARGETS_UP View Gene Set 2.451e-15 68 1.955e-13 30 Genes up-regulated in P493-6 cells (Burkitt's lymphoma) induced to express MYC [Gene ID=4609]. www.broad.mit.e...
Broad SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 View Gene Set 2.837e-15 435 2.189e-13 31 Cluster 6 of method A: up-regulation of these genes in patients with non???small cell lung cancer (NSCLC) predicts poor survival outcome. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP View Gene Set 4.697e-15 589 3.511e-13 32 Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN View Gene Set 3.716e-14 308 2.694e-12 33 Genes down-regulated in non-metastatic breast cancer tumors having type 1 amplification in the 20q13 region; involves ZNF217 [Gene ID=7764] locus only. www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_24HR_UP View Gene Set 8.009e-14 537 5.635e-12 34 Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h. www.broad.mit.e...
Broad KOBAYASHI_EGFR_SIGNALING_24HR_DN View Gene Set 1.056e-13 243 7.219e-12 35 Genes down-regulated in H1975 cells (non-small cell lung cancer NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 24h. www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN View Gene Set 6.101e-13 46 3.944e-11 36 Cluster 6: genes down-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] in combination with serum but not affected by serum alone; they are also up-regulated by MYC alone. www.broad.mit.e...
Broad WONG_MITOCHONDRIA_GENE_MODULE View Gene Set 6.055e-13 208 3.944e-11 36 Genes that comprise the mitochondria gene module www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP View Gene Set 7.739e-13 45 4.871e-11 38 Cluster 5: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] alone or in combination with serum but not by serum alone. www.broad.mit.e...
Broad BIDUS_METASTASIS_UP View Gene Set 1.108e-12 203 6.795e-11 39 Genes up-regulated in endometroid endometrial tumors from patients with lymph node metastases compared to those without the metastases. www.broad.mit.e...
Broad PENG_GLUTAMINE_DEPRIVATION_DN View Gene Set 1.866e-12 84 1.116e-10 40 Genes down-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation. www.broad.mit.e...
Broad MISSIAGLIA_REGULATED_BY_METHYLATION_DN View Gene Set 5.572e-12 96 3.174e-10 41 Genes down-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668] a DNA hypomethylating agent similar to azacitidine [PubChem=9444]. www.broad.mit.e...
Broad FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP View Gene Set 5.499e-12 144 3.174e-10 41 Genes up-regulated in genomically unstable Ewing's sarcoma tumors compared to the stable ones. www.broad.mit.e...
Broad DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP View Gene Set 7.984e-12 1353 4.43e-10 43 Genes up-regulated in CD34+ [Gene ID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients compared to those from normal donors. www.broad.mit.e...
Broad FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN View Gene Set 8.149e-12 43 4.43e-10 43 Genes down-regulated in MCF-7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4-hydroxytamoxifen raloxifene or ICI 182780 but not by estradiol [PubChem=44959 5035 3478439 5757]. www.broad.mit.e...
Broad ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER View Gene Set 1.509e-11 138 8.024e-10 45 The 'Cervical Cancer Proliferation Cluster' (CCPC): genes whose expression in cervical carcinoma positively correlates with that of the HPV E6 and E7 oncogenes; they are also differentially expressed according to disease outcome. www.broad.mit.e...
Broad SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY View Gene Set 2.208e-11 31 1.148e-09 46 Cluster 3: genes strongly up-regulated in B493-6 cells (B lymphocytes) by a combination of MYC [Gene ID=4609] and serum but not by each of them alone. www.broad.mit.e...
Broad BENPORATH_ES_1 View Gene Set 2.413e-11 367 1.228e-09 47 Set 'ES exp1': genes overexpressed in human embryonic stem cells according to 5 or more out of 20 profiling studies. www.broad.mit.e...
Broad MITSIADES_RESPONSE_TO_APLIDIN_DN View Gene Set 2.545e-11 241 1.242e-09 48 Genes down-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164] a marine-derived compound with potential anti-cancer properties. www.broad.mit.e...
Broad BLUM_RESPONSE_TO_SALIRASIB_DN View Gene Set 2.523e-11 332 1.242e-09 48 Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [Gene ID=3265]. www.broad.mit.e...
Broad GRADE_COLON_AND_RECTAL_CANCER_UP View Gene Set 2.675e-11 213 1.28e-09 50 Up-regulated genes in both rectal and colon carcinoma compared to normal mucosa samples. www.broad.mit.e...
Broad SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP View Gene Set 3.183e-11 143 1.493e-09 51 Up-regulated genes whose expression correlated with histologic grade of invasive breast cancer tumors: comparison of grade 1 vs grade 3. www.broad.mit.e...
Broad WINNEPENNINCKX_MELANOMA_METASTASIS_UP View Gene Set 3.64e-11 152 1.674e-09 52 Genes from the 254-gene classifier which were up-regulated in melanoma patients with a reported distant metastasis within 4 years. www.broad.mit.e...
Broad LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN View Gene Set 5.373e-11 158 2.425e-09 53 Genes down-regulated in Wilm's tumor samples compared to fetal kidney. www.broad.mit.e...
Broad WHITEFORD_PEDIATRIC_CANCER_MARKERS View Gene Set 6.171e-11 92 2.734e-09 54 Differentially expressed genes in a panel of xenografts representing 8 common pediatric tumors compared to the normal tissues. www.broad.mit.e...
Broad PAL_PRMT5_TARGETS_UP View Gene Set 6.947e-11 178 3.021e-09 55 Genes up-regulated in NIH-3T3 cells (fibroblast) after knockdown of PRMT5 [Gene ID=10419] by RNAi. www.broad.mit.e...
Broad MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP View Gene Set 7.438e-11 359 3.177e-09 56 The postradiation tumor escape signature: genes up-regulated in tumors from irradiated stroma vs those from non-irradiated stroma. www.broad.mit.e...
Broad MARKEY_RB1_ACUTE_LOF_DN View Gene Set 1.411e-10 201 5.922e-09 57 Genes down-regulated in adult fibroblasts with inactivated RB1 [Gene ID=5925] by Cre-lox: acute loss of function (LOF) of RB1. www.broad.mit.e...
Broad RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN View Gene Set 3.478e-10 351 1.424e-08 58 Genes down-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids. www.broad.mit.e...
Broad RIZ_ERYTHROID_DIFFERENTIATION View Gene Set 3.511e-10 71 1.424e-08 58 Selected gradually up-regulated genes in the TLX1 [Gene ID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). www.broad.mit.e...
Broad BENPORATH_MYC_MAX_TARGETS View Gene Set 5.823e-10 768 2.321e-08 60 Set 'Myc targets2': targets of c-Myc [Gene ID=4609] and Max [Gene ID=4149] identified by ChIP on chip in a Burkitt???s lymphoma cell line; overlap set. www.broad.mit.e...
Broad GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN View Gene Set 1.257e-09 148 4.931e-08 61 Genes down-regulated in the A673 cells (Ewing sarcoma) after double knockdown of both FLI1 and DAX1 [Gene ID=2313 190] by RNAi. www.broad.mit.e...
Broad GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP View Gene Set 1.379e-09 180 5.321e-08 62 Genes up-regulated in quiescent CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors compared to the dividing cells from CML (chronic myeloid leukemia) patients. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 View Gene Set 1.835e-09 131 6.966e-08 63 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 14. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP View Gene Set 2.52e-09 184 9.419e-08 64 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G3 defined by unsupervised clustering. www.broad.mit.e...
Broad KAUFFMANN_DNA_REPLICATION_GENES View Gene Set 2.879e-09 128 1.06e-07 65 Genes involved in DNA replication compiled manually by the authors. www.broad.mit.e...
Broad BENPORATH_CYCLING_GENES View Gene Set 4.568e-09 630 1.656e-07 66 Genes showing cell-cycle stage-specific expression [PMID=12058064]. www.broad.mit.e...
Broad ZHANG_RESPONSE_TO_CANTHARIDIN_DN View Gene Set 7.935e-09 60 2.833e-07 67 Genes down-regulated in HL-60 cells (promyeloid leukemia) by cantharidin [PubChem=6708701]. www.broad.mit.e...
Broad RAMALHO_STEMNESS_UP View Gene Set 9.042e-09 192 3.181e-07 68 Genes enriched in embryonic neural and hematopoietic stem cells. www.broad.mit.e...
Broad VECCHI_GASTRIC_CANCER_EARLY_UP View Gene Set 9.449e-09 408 3.229e-07 69 Up-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. www.broad.mit.e...
Broad ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN View Gene Set 9.354e-09 42 3.229e-07 69 Genes down-regulated in P493-6 cells (B lymphocyte) by MYC [Gene ID=4609] and up-regulated by RNAi knockdown of TFRC [Gene ID=7037]. www.broad.mit.e...
Broad GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN View Gene Set 1.189e-08 86 4.007e-07 71 Genes down-regulated in quiescent vs dividing CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors. www.broad.mit.e...
Broad MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP View Gene Set 1.4e-08 92 4.651e-07 72 Genes correlated with the early tumor onset in the Emu-myc transgenic mouse lymphoma model. www.broad.mit.e...
Broad PENG_RAPAMYCIN_RESPONSE_DN View Gene Set 1.725e-08 69 5.654e-07 73 Genes down-regulated in BJUB cells (B-lymphoma) in response to rapamycin [PubChem=6610346] treatment. www.broad.mit.e...
Broad ZHANG_BREAST_CANCER_PROGENITORS_UP View Gene Set 2.026e-08 370 6.548e-07 74 Genes changed in cancer stem cells isolated from mammary tumors compared to the non-tumorigenic cells. www.broad.mit.e...
Broad FOURNIER_ACINAR_DEVELOPMENT_LATE_2 View Gene Set 2.733e-08 265 8.715e-07 75 Genes identified by method 2 as coordinately down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro. www.broad.mit.e...
Broad DAIRKEE_TERT_TARGETS_UP View Gene Set 3.426e-08 317 1.078e-06 76 Genes up-regulated in non-spontaneously immortalizing (NSI) primary breast cancer tumor cultures upon expression of TERT [Gene ID=7015] off a retroviral vector. www.broad.mit.e...
Broad FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN View Gene Set 4.891e-08 76 1.519e-06 77 Top 100 genes positively (UP) and negatively (DN) associated with T-cell acute lymphoblastic leukemia MLL T-ALL) expressing MLL-ENL fusion [Gene ID=4297 4298]. www.broad.mit.e...
Broad MOOTHA_PGC View Gene Set 6.234e-08 329 1.912e-06 78 Genes up-regulated in differentiating C2C12 cells (myoblasts) upon expression of PPARGC1A [Gene ID=10891] off an adenoviral vector. www.broad.mit.e...
Broad PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP View Gene Set 6.558e-08 53 1.986e-06 79 The XPRSS-Int network genes up-regulated in breast tumors from patients with germline mutations in BRCA1 [Gene ID=672] compared to those with the wild type allele. www.broad.mit.e...
Broad BHATTACHARYA_EMBRYONIC_STEM_CELL View Gene Set 9.128e-08 76 2.729e-06 80 The 'stemnes' signature: genes up-regulated and common to 6 human embryonic stem cell lines tested. www.broad.mit.e...
Broad HORIUCHI_WTAP_TARGETS_DN View Gene Set 1.206e-07 289 3.563e-06 81 Genes down-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [Gene ID=9589] by RNAi. www.broad.mit.e...
Broad ELVIDGE_HYPOXIA_DN View Gene Set 2.077e-07 136 6.059e-06 82 Genes down-regulated in MCF7 cells (breast cancer) under hypoxia conditions. www.broad.mit.e...
Broad HESS_TARGETS_OF_HOXA9_AND_MEIS1_UP View Gene Set 2.795e-07 59 8.054e-06 83 Genes up-regulated in hematopoietic precursor cells conditionally expressing HOXA9 and MEIS1 [Gene ID=3205 4211]. www.broad.mit.e...
Broad IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR View Gene Set 3.079e-07 100 8.768e-06 84 Genes in the expression cluster 'Early Progenitors Shared': up-regulated in hematopoietic progenitors from adult bone marrow and from fetal liver. www.broad.mit.e...
Broad HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP View Gene Set 3.315e-07 93 9.33e-06 85 Genes up-regulated during differentiation from large pre-BII to small pre-BII lymphocyte. www.broad.mit.e...
Broad FUJII_YBX1_TARGETS_DN View Gene Set 3.485e-07 139 9.692e-06 86 Genes down-regulated in MCF-7 cells (breast cancer) after knockdown of YBX1 [Gene ID=4904] by RNAi. www.broad.mit.e...
Broad ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN View Gene Set 3.784e-07 61 1.04e-05 87 Genes down-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]. www.broad.mit.e...
Broad WONG_PROTEASOME_GENE_MODULE View Gene Set 4.26e-07 46 1.152e-05 88 Genes that comprise the proteasome gene module www.broad.mit.e...
Broad LY_AGING_OLD_DN View Gene Set 4.285e-07 47 1.152e-05 88 Genes up-regulated in fibroblasts from old individuals compared to those from young donors. www.broad.mit.e...
Broad KANG_DOXORUBICIN_RESISTANCE_UP View Gene Set 4.854e-07 53 1.29e-05 90 Genes differentialy expressed in gastric cancer cell lines: doxorubicin [PubChem=31703] resistant vs sensitive. www.broad.mit.e...
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP View Gene Set 4.958e-07 469 1.303e-05 91 Genes up-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. www.broad.mit.e...
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN View Gene Set 5.675e-07 51 1.475e-05 92 Genes from the turquoise module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphocholine (oxPAPC). www.broad.mit.e...
Broad HOSHIDA_LIVER_CANCER_SUBCLASS_S2 View Gene Set 6.031e-07 114 1.551e-05 93 Genes from 'subtype S2' signature of hepatocellular carcinoma (HCC): proliferation MYC and AKT1 [Gene ID=4609 207] activation. www.broad.mit.e...
Broad NUYTTEN_EZH2_TARGETS_DN View Gene Set 7.046e-07 859 1.793e-05 94 Genes down-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [Gene ID=2146] by RNAi. www.broad.mit.e...
Broad KAUFFMANN_DNA_REPAIR_GENES View Gene Set 7.588e-07 205 1.91e-05 95 Genes involved in DNA repair compiled manually by the authors. www.broad.mit.e...
Broad BILD_MYC_ONCOGENIC_SIGNATURE View Gene Set 8.079e-07 187 2.013e-05 96 Genes selected in supervised analyses to discriminate cells expressing c-Myc [Gene ID=4609] from control cells expressing GFP. www.broad.mit.e...
Broad NAKAMURA_CANCER_MICROENVIRONMENT_DN View Gene Set 8.654e-07 45 2.134e-05 97 Genes down-regulated in pancreatic cancer cells grown in orthotopic xenograft tumors compared to those grown in vitro. www.broad.mit.e...
Broad DANG_REGULATED_BY_MYC_UP View Gene Set 9.53e-07 65 2.326e-05 98 Genes up-regulated by MYC [Gene ID=4609] according to the MYC Target Gene Database. www.broad.mit.e...
Broad MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN View Gene Set 9.875e-07 212 2.386e-05 99 Genes down-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199]. www.broad.mit.e...
Broad MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN View Gene Set 1.508e-06 121 3.607e-05 100 Genes distinguishing in multiple myeloma (MM) samples with lower expression of TACI [Gene ID=23495]. www.broad.mit.e...
Broad SONG_TARGETS_OF_IE86_CMV_PROTEIN View Gene Set 1.695e-06 49 4.013e-05 101 Cellular genes up-regulated in forskin fibroblasts by expression of CMV EI86 protein off an adenovirus vector. www.broad.mit.e...
Broad MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN View Gene Set 1.81e-06 42 4.244e-05 102 Genes down-regulated in normal bone marrow plasma cells (BMPC) compared to polyclonal plasmablasts (PPC) that also distinguished multiple myeloma (MM) samples by expression of levels of TACI [Gene ID=23495]. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP View Gene Set 3.07e-06 36 7.061e-05 103 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_DN View Gene Set 3.07e-06 36 7.061e-05 103 Down-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors. www.broad.mit.e...
Broad MORI_IMMATURE_B_LYMPHOCYTE_DN View Gene Set 3.15e-06 52 7.177e-05 105 Down-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the immature B stage. www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP View Gene Set 3.773e-06 681 8.473e-05 106 Genes up-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue. www.broad.mit.e...
Broad EGUCHI_CELL_CYCLE_RB1_TARGETS View Gene Set 3.79e-06 19 8.473e-05 106 RB1 [Gene ID=5925] target genes involved in cell cycle regulation: genes down-regulated by doxorubicin [PubChem=31703] only in cells expressing RB1. www.broad.mit.e...
Broad ENK_UV_RESPONSE_KERATINOCYTE_DN View Gene Set 4.142e-06 475 9.173e-05 108 Genes down-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 View Gene Set 5.455e-06 165 0.0001197 109 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 17. www.broad.mit.e...
Broad GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN View Gene Set 6.517e-06 160 0.0001417 110 Genes down-regulated in metastatic breast cancer tumors having type 2 amplification in the 20q13 region; involves MYBL2 STK6 and ZNF217 [Gene ID=4605 6790 7764] www.broad.mit.e...
Broad BENPORATH_MYC_TARGETS_WITH_EBOX View Gene Set 7.089e-06 229 0.0001528 111 Set 'Myc targets1': targets of c-Myc [Gene ID=4609] identified by ChIP on chip in cultured cell lines focusing on E-box???containing genes; high affinity bound subset www.broad.mit.e...
Broad PUJANA_BREAST_CANCER_LIT_INT_NETWORK View Gene Set 7.819e-06 100 0.000167 112 Genes constituting the LIT-Int network of proteins interacting with breast cancer reference proteins BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200]; the interactions were manually curated from the literature. www.broad.mit.e...
Broad REN_BOUND_BY_E2F View Gene Set 9.92e-06 47 0.00021 113 Genes whose promoters were bound by E2F1 [Gene ID=1869] and E2F4 [Gene ID=1874] in the primary fibroblasts WI-38 by ChIP on chip assay. www.broad.mit.e...
Broad MENSSEN_MYC_TARGETS View Gene Set 1.097e-05 16 0.0002301 114 Genes up-regulated by adenoviral expression of c-MYC [Gene ID=4609] in HUVEC cells (umbilical vein endothelium). www.broad.mit.e...
Broad XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_DN View Gene Set 1.182e-05 14 0.0002458 115 Genes down-regulated synergistically in NB4 cells (acute promyelocytic leukemia APL) by tretinoin and NSC682994 [PubChem=5538 388304]. www.broad.mit.e...
Broad MORI_LARGE_PRE_BII_LYMPHOCYTE_UP View Gene Set 1.263e-05 52 0.0002605 116 Up-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Large Pre-BII stage. www.broad.mit.e...
Broad KAUFFMANN_MELANOMA_RELAPSE_UP View Gene Set 1.31e-05 57 0.0002678 117 DNA repair and replication genes up-regulated in melanoma patients who will relapse vs patients who will not. www.broad.mit.e...
Broad MATTIOLI_MGUS_VS_PCL View Gene Set 1.642e-05 109 0.0003329 118 Genes changed in MGUS (monoclonal gammopathy of undetermined significance) compared to PCL (plasma cell leukemia) samples. www.broad.mit.e...
Broad SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP View Gene Set 1.753e-05 45 0.0003523 119 Top 50 up-regulated markers distinguishing diffuse large B-cell lymphoma (DLBCL) from follicular lymphoma (FL) samples. www.broad.mit.e...
Broad ZHAN_MULTIPLE_MYELOMA_SUBGROUPS View Gene Set 2.055e-05 28 0.0004096 120 Top genes up-regulated in MM4 vs MM1 subgroup of multiple myeloma samples. www.broad.mit.e...
Broad BASSO_B_LYMPHOCYTE_NETWORK View Gene Set 2.495e-05 136 0.0004892 121 Genes which comprise the top 1% of highly interconnected genes (major hubs) that account for most of gene interactions in the reconstructed regulatory networks from expression profiles in B lymphocytes. www.broad.mit.e...
Broad GALE_APL_WITH_FLT3_MUTATED_UP View Gene Set 2.476e-05 52 0.0004892 121 Genes up-regulated in acute promyelocytic leukemia (APL) patients with mutated FLT3 [Gene ID=2322]. www.broad.mit.e...
Broad ELVIDGE_HIF1A_TARGETS_UP View Gene Set 2.553e-05 64 0.0004965 123 Genes up-regulated in MCF7 cells (breast cancer) after knockdown of HIF1A [Gene ID=3091] by RNAi. www.broad.mit.e...
Broad CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP View Gene Set 3.198e-05 51 0.000612 124 Protein biosynthesis transport or catabolism genes up-regulated in hyperploid multiple myeloma (MM) compared to the non-hyperploid MM samples. www.broad.mit.e...
Broad RHODES_UNDIFFERENTIATED_CANCER View Gene Set 3.176e-05 60 0.000612 124 Genes commonly up-regulated in undifferentiated cancer relative to well-differentiated cancer based on the meta-analysis of the OncoMine gene expression database. www.broad.mit.e...
Broad ODONNELL_TFRC_TARGETS_DN View Gene Set 3.548e-05 131 0.0006737 126 Genes dpwn-regulated in P493-6 cells (B lymphocyte) upon knockdown of TFRC [Gene ID=7037] by RNAi. www.broad.mit.e...
Broad KIM_MYC_AMPLIFICATION_TARGETS_UP View Gene Set 3.97e-05 155 0.0007477 127 Genes positively correlated with amplifications of MYC [Gene ID=4609] in SCLC (small cell lung cancer) cell lines. www.broad.mit.e...
Broad UDAYAKUMAR_MED1_TARGETS_UP View Gene Set 4.475e-05 129 0.0008344 128 Genes up-regulated in HeLa cells after knockdown of MED1 [Gene ID=5469] by RNAi. www.broad.mit.e...
Broad DAIRKEE_CANCER_PRONE_RESPONSE_BPA View Gene Set 4.5e-05 46 0.0008344 128 'Cancer prone response profile' (CPRP): genes changed in response to bisphenol A [PubChem=6623] in epithelial cell cultures from patients at high risk of breast cancer. www.broad.mit.e...
Broad CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP View Gene Set 4.656e-05 135 0.0008503 130 Genes up-regulated in CD4+ [Gene ID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]. www.broad.mit.e...
Broad BENPORATH_PROLIFERATION View Gene Set 4.642e-05 140 0.0008503 130 Set 'Proliferation Cluster': genes defined in human breast tumor expression data. www.broad.mit.e...
Broad LY_AGING_MIDDLE_DN View Gene Set 4.743e-05 15 0.0008596 132 Genes down-regulated in fibroblasts from middle-age individuals compared to those from the young donors. www.broad.mit.e...
Broad LIU_SOX4_TARGETS_DN View Gene Set 4.987e-05 297 0.0008969 133 Genes down-regulated in LNCaP cells (prostate cancer) by overexpression of SOX4 [Gene ID=6659] and up-regulated by its RNAi knockdown. www.broad.mit.e...
Broad KIM_GASTRIC_CANCER_CHEMOSENSITIVITY View Gene Set 5.85e-05 97 0.001044 134 Genes up-regulated in gastric cancer patients refractory to chemotherapy treatment with 5-fluorouracil and cisplatin [PubChem=3385 2767] compared to the sensitive state. www.broad.mit.e...
Broad SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN View Gene Set 6.209e-05 22 0.001095 135 Cell cycle genes changed in H1299 cells (lung cancer) after overexpression of either P53 [Gene ID=7157] or P73 [Gene ID=7161]. www.broad.mit.e...
Broad MOOTHA_VOXPHOS View Gene Set 6.224e-05 82 0.001095 135 Genes involved in oxidative phosphorylation; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. www.broad.mit.e...
Broad LEE_METASTASIS_AND_RNA_PROCESSING_UP View Gene Set 6.518e-05 15 0.001138 137 Components of RNA post-transcriptional modification machinery up-regulated in MDA-MB-435 cells (breast cancer) whose metastatic potential has been reduced by expression of NME1 [Gene ID=4830]. www.broad.mit.e...
Broad GOLDRATH_HOMEOSTATIC_PROLIFERATION View Gene Set 8.015e-05 154 0.001388 138 Up-regulated in CD8+ [Gene ID=925] T lymphocytes undergoing homeostatic proliferation (HP) versus the naive cells; these genes are not up-regulated versus effector or memory cell population. www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 View Gene Set 8.064e-05 93 0.001388 138 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 11. www.broad.mit.e...
Broad DAZARD_RESPONSE_TO_UV_NHEK_DN View Gene Set 8.96e-05 256 0.001531 140 Genes down-regulated in NHEK cells (normal keratinocytes) by UV-B irradiation. www.broad.mit.e...
Broad PENG_LEUCINE_DEPRIVATION_DN View Gene Set 9.466e-05 50 0.001606 141 Genes down-regulated in BJAB cells (B-lymphoma) after leucine [PubChem=857] deprivation. www.broad.mit.e...
Broad LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP View Gene Set 0.0001052 168 0.001753 142 Genes with copy number gains in primary neuroblastoma tumors. www.broad.mit.e...
Broad MOHANKUMAR_TLX1_TARGETS_UP View Gene Set 0.0001055 388 0.001753 142 Up-regulated in MCF7 cells (breast cancer) by TLX1 (HOX11) [Gene ID=3195]. www.broad.mit.e...
Broad AMUNDSON_GAMMA_RADIATION_RESPONSE View Gene Set 0.0001055 36 0.001753 142 Genes down-regulated across the entire panel of NCI-60 cell lines in response to gamma radiation. www.broad.mit.e...
Broad CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP View Gene Set 0.0001157 47 0.001908 145 Genes up-regulated by 2-methoxyestradiol (2ME2) [PubChem=1573] in the MM.1S cell line (multiple myeloma) sensitive to dexamethasone [PubChem=5743]. www.broad.mit.e...
Broad RHODES_CANCER_META_SIGNATURE View Gene Set 0.0001206 54 0.001977 146 Genes commonly up-regulated in cancer relative to normal tissue according to the meta-analysis of the OncoMine gene expression database. www.broad.mit.e...
Broad SMID_BREAST_CANCER_LUMINAL_A_DN View Gene Set 0.000122 17 0.001985 147 Genes down-regulated in the luminal A subtype of breast cancer. www.broad.mit.e...
Broad MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN View Gene Set 0.0001319 53 0.002131 148 Genes commonly down-regulated in SK-N-BE cells (neuroblastoma) after RNAi knockdown of CCND1 and CDK4 [Gene ID=595 1019]. www.broad.mit.e...
Broad BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP View Gene Set 0.0001492 190 0.002395 149 Genes up-regulated in medullary breast cancer (MBC) relative to ductal breast cancer (DBD). www.broad.mit.e...
Broad MUNSHI_MULTIPLE_MYELOMA_DN View Gene Set 0.0001837 9 0.002929 150 Genes down-regulated in multiple myeloma (MM) compared to normal plasma cells from the patient's identical twin. www.broad.mit.e...
Broad DAZARD_UV_RESPONSE_CLUSTER_G6 View Gene Set 0.0002052 122 0.003251 151 Cluster G6: genes increasingly down-regulated in NHEK cells (normal keratinocyte) after UV-B irradiation. www.broad.mit.e...
Broad CAFFAREL_RESPONSE_TO_THC_DN View Gene Set 0.0002333 25 0.003671 152 Genes down-regulated in EVSA-T cells (breast cancer) treated THC (delta-9-tetrahydrocannabinol) [PubChem=6610319]. www.broad.mit.e...
Broad CHANG_CYCLING_GENES View Gene Set 0.0002349 49 0.003672 153 Fibroblast serum response genes showing periodic expression during the cell cycle; excluded from the core serum response signature. www.broad.mit.e...
Broad PRAMOONJAGO_SOX4_TARGETS_DN View Gene Set 0.0002762 51 0.00429 154 Genes down-regulated in ACC3 cells (adenoid cystic carcinoma) after knockdown of SOX4 [Gene ID=6659] by RNAi. www.broad.mit.e...
Broad POMEROY_MEDULLOBLASTOMA_PROGNOSIS_DN View Gene Set 0.0002794 39 0.004312 155 Top marker genes in medulloblastoma associated with poor response to treatment (poor outcome). www.broad.mit.e...
Broad MOOTHA_GLUCONEOGENESIS View Gene Set 0.000309 32 0.004739 156 Genes involved in gluconeogenesis; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. www.broad.mit.e...
Broad MOOTHA_TCA View Gene Set 0.0003121 15 0.004754 157 Tricarboxylic acid related genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. www.broad.mit.e...
Broad KALMA_E2F1_TARGETS View Gene Set 0.0003167 11 0.004795 158 DNA replication genes up-regulated in a Rat-1a cell line (fibroblast) by expression of E2F1 [Gene ID=1869]. www.broad.mit.e...
Broad RIZ_ERYTHROID_DIFFERENTIATION_CCNE1 View Gene Set 0.0003235 38 0.004867 159 Selected gradually up-regulated genes whose expression profile follows that of CCNE1 [Gene ID=898] in the TLX1 [Gene ID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). www.broad.mit.e...
Broad DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2 View Gene Set 0.0003453 111 0.005162 160 'Cancer prone response profile' (CPRP): genes common to estradiol and bisphenol A [PubChem=5757 6623] response of epithelial cell cultures from patients at high risk of breast cancer. www.broad.mit.e...
Broad HELLER_HDAC_TARGETS_DN View Gene Set 0.0003626 250 0.005387 161 Genes down-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]. www.broad.mit.e...
Broad VANTVEER_BREAST_CANCER_BRCA1_UP View Gene Set 0.0004154 32 0.006134 162 Up-regulated genes from the optimal set of 100 markers discriminating ER(-) breast cancer tumors by BRCA1 [Gene ID=672] mutation status. www.broad.mit.e...
Broad RAMASWAMY_METASTASIS_UP View Gene Set 0.00042 63 0.006164 163 Up-regulated genes in metastatic vs primary solid tumors. www.broad.mit.e...
Broad AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN View Gene Set 0.0004653 218 0.006786 164 Down-regulated genes whose expression correlates with copy number losses in pancreatic adenocarcinoma cell lines and primary tumor specimens. www.broad.mit.e...
Broad LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER View Gene Set 0.0004975 167 0.007212 165 Overexpressed genes with amplified copy number across 27 non-small cell lung cancer (NSCLC) cell lines. www.broad.mit.e...
Broad JISON_SICKLE_CELL_DISEASE_DN View Gene Set 0.0005588 168 0.008052 166 Genes down-regulated in peripheral blood mononuclear cells (PBMC) from sickle cell disease patients compared to those from healthy subjects. www.broad.mit.e...
Broad DAZARD_UV_RESPONSE_CLUSTER_G5 View Gene Set 0.0006433 10 0.00916 167 Cluster G5: genes up-regulated in NHEK cells (normal keratinocyte) at 3 h and 24 h time points after UV-B irradiation. www.broad.mit.e...
Broad LEE_LIVER_CANCER_SURVIVAL_DN View Gene Set 0.0006404 123 0.00916 167 Genes highly expressed in hepatocellular carcinoma with poor survival. www.broad.mit.e...
Broad YU_MYC_TARGETS_UP View Gene Set 0.0006511 37 0.009215 169 Genes up-regulated in B cell lymphoma tumors expressing an activated form of MYC [Gene ID=4609]. www.broad.mit.e...
Broad SHEPARD_CRUSH_AND_BURN_MUTANT_UP View Gene Set 0.0006702 135 0.00943 170 Human orthologs of genes up-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [Gene ID=4605]. www.broad.mit.e...
Broad ELVIDGE_HIF1A_AND_HIF2A_TARGETS_UP View Gene Set 0.0006846 38 0.009533 171 Genes up-regulated in MCF7 cells (breast cancer) after knockdown of both HIF1A and HIF2A [Gene ID=3091 2034] by RNAi. www.broad.mit.e...
Broad SAKAI_TUMOR_INFILTRATING_MONOCYTES_DN View Gene Set 0.0006855 79 0.009533 171 Selected genes down-regulated in inflammatory monocytes infiltrating hepatocellular carcinoma (HCC). www.broad.mit.e...
Broad LINDGREN_BLADDER_CANCER_CLUSTER_3_UP View Gene Set 0.0007084 314 0.009739 173 Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors. www.broad.mit.e...
Broad WEST_ADRENOCORTICAL_TUMOR_UP View Gene Set 0.0007051 283 0.009739 173 Up-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue. www.broad.mit.e...
Broad SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP View Gene Set 0.0007409 16 0.01013 175 Genes up-regulated in MCF10A cells (breast cancer) grown at low (mesenchymal phenotype) compared to those grown at high (epithelial basal-like phenotype) confluency. www.broad.mit.e...
Broad BORCZUK_MALIGNANT_MESOTHELIOMA_UP View Gene Set 0.0007559 290 0.01027 176 Genes up-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma. www.broad.mit.e...
Broad BENPORATH_ES_2 View Gene Set 0.0008496 39 0.01144 177 Set 'Set 'ES exp2': genes overexpressed in human embryonic stem cells according to a meta-analysis of 8 profiling studies. www.broad.mit.e...
Broad ZHAN_MULTIPLE_MYELOMA_PR_UP View Gene Set 0.0008512 43 0.01144 177 Top 50 up-regulated genes in cluster PR of multiple myeloma samples characterized by increased expression of proliferation and cell cycle genes. www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP View Gene Set 0.001158 220 0.01548 179 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors. www.broad.mit.e...
Broad COLLER_MYC_TARGETS_UP View Gene Set 0.001304 12 0.01723 180 Genes regulated by forced expression of MYC [Gene ID=4609] in 293T (transformed fetal renal cell). www.broad.mit.e...
Broad JAIN_NFKB_SIGNALING View Gene Set 0.001301 73 0.01723 180 Genes abnormally regulated in response to CD40L and IL4 [Gene ID=959 3565] stimulation of B lymphocytes from patients with a hypomorphic mutation of IKBKG [Gene ID=8517]. www.broad.mit.e...
Broad NIKOLSKY_BREAST_CANCER_16Q24_AMPLICON View Gene Set 0.001317 48 0.01731 182 Genes within amplicon 16q24 identified in a copy number alterations study of 191 breast tumor samples. www.broad.mit.e...
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP View Gene Set 0.001347 44 0.0176 183 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G123 defined by unsupervised clustering. www.broad.mit.e...
Broad CAFFAREL_RESPONSE_TO_THC_24HR_5_DN View Gene Set 0.001418 47 0.01843 184 Genes down-regulated in EVSA-T cells (breast cancer) treated with 5 micromolar THC (delta-9-tetrahydrocannabinol) [PubChem=6610319] for 24 h. www.broad.mit.e...
Broad APPIERTO_RESPONSE_TO_FENRETINIDE_DN View Gene Set 0.001444 40 0.01867 185 Genes down-regulated in A2780 cells (ovarian carcinoma) exposed to fenretinide [PubChem=1744]. www.broad.mit.e...
Broad FARMER_BREAST_CANCER_CLUSTER_2 View Gene Set 0.001467 33 0.01886 186 Cluster 2: selected proliferation and 8q amplicon genes clustered together across breast cancer samples. www.broad.mit.e...
Broad ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN View Gene Set 0.001664 346 0.02107 187 Genes down-regulated in normal tissue adjacent to liver tumor compared to the normal liver samples. www.broad.mit.e...
Broad MILI_PSEUDOPODIA_HAPTOTAXIS_UP View Gene Set 0.00166 452 0.02107 187 Transcripts enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin FN1 [Gene ID=2335]. www.broad.mit.e...
Broad CHUANG_OXIDATIVE_STRESS_RESPONSE_DN View Gene Set 0.001663 10 0.02107 187 Genes down-regulated in MCF7 cells (breast cancer) after treatment with the oxydants: hydrogen peroxyde menadione and t-butyl hydroperoxyde [PubChem=784 4055 6410]. www.broad.mit.e...
Broad JAZAG_TGFB1_SIGNALING_DN View Gene Set 0.001818 35 0.02289 190 Genes down-regulated in PANC-1-puro cells (pancreatic cancer) stimulated by TGF1B [Gene ID=7040] for 2 h. www.broad.mit.e...
Broad WAKASUGI_HAVE_ZNF143_BINDING_SITES View Gene Set 0.001828 55 0.02289 191 DNA repair genes whose promoters contain putative ZNF143 [Gene ID=7702] binding sites. www.broad.mit.e...
Broad KRASNOSELSKAYA_ILF3_TARGETS_DN View Gene Set 0.001883 38 0.02346 192 Down-regulated in GHOST(3)CXCR4 cells (osteosarcoma) upon ectopic expression of ILF3 [Gene ID=3609]. www.broad.mit.e...
Broad NIKOLSKY_BREAST_CANCER_7P15_AMPLICON View Gene Set 0.002039 11 0.02527 193 Genes within amplicon 7p15 identified in a copy number alterations study of 191 breast tumor samples. www.broad.mit.e...
Broad LOPEZ_MBD_TARGETS View Gene Set 0.002156 855 0.02659 194 Genes up-regulated in HeLa cells (cervical cancer) after simultaneus knockdown of all three MBD (methyl-CpG binding domain) proteins MeCP2 MBD1 and MBD2 [Gene ID=4204 4152 8932] by RNAi. www.broad.mit.e...
Broad FUNG_IL2_SIGNALING_1 View Gene Set 0.002294 10 0.02814 195 Genes up-regulated by IL2 [Gene ID=3558] in both primary thymocytes and T1 cells (primary thymocytes immortalized by Tax an HTLV-1 encoded gene). www.broad.mit.e...
Broad TSENG_IRS1_TARGETS_UP View Gene Set 0.002324 102 0.02837 196 Up-regulated in brown preadipocytes with IRS1 [Gene ID=3667] knockout vs wild type controls; the knockouts have severe defects in adipocyte differentiation. www.broad.mit.e...
Broad GLINSKY_CANCER_DEATH_UP View Gene Set 0.002347 6 0.0285 197 Genes whose over-expression is associated with the risk of death in multiple cancer types www.broad.mit.e...
Broad FURUKAWA_DUSP6_TARGETS_PCI35_DN View Gene Set 0.002572 66 0.03107 198 Genes down-regulated in PCI-35 cells (pancreatic cancer lack endogenous DUSP6 [Gene ID=1848]) upon expression of DUSP6 off an adenoviral vector. www.broad.mit.e...
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP View Gene Set 0.002717 17 0.03266 199 Genes from the red module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC). www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_14HR_UP View Gene Set 0.002737 150 0.03274 200 Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not up-regulated at the previous time point 12 h. www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.BIOCARTA

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad BIOCARTA_RANMS_PATHWAY View Gene Set 2.096e-05 10 0.004548 1 Role of Ran in mitotic spindle regulation www.broad.mit.e...
Broad BIOCARTA_SARS_PATHWAY View Gene Set 0.0003479 10 0.03775 2 The SARS-coronavirus Life Cycle www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.KEGG

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad KEGG_SPLICEOSOME View Gene Set 2.518e-21 118 4.684e-19 1 Spliceosome www.broad.mit.e...
Broad KEGG_AMINOACYL_TRNA_BIOSYNTHESIS View Gene Set 2.289e-14 41 2.129e-12 2 Aminoacyl-tRNA biosynthesis www.broad.mit.e...
Broad KEGG_RNA_DEGRADATION View Gene Set 1.108e-07 59 6.871e-06 3 RNA degradation www.broad.mit.e...
Broad KEGG_PYRIMIDINE_METABOLISM View Gene Set 3.783e-07 98 1.407e-05 4 Pyrimidine metabolism www.broad.mit.e...
Broad KEGG_DNA_REPLICATION View Gene Set 3.255e-07 36 1.407e-05 4 DNA replication www.broad.mit.e...
Broad KEGG_BASE_EXCISION_REPAIR View Gene Set 8.565e-07 35 2.655e-05 6 Base excision repair www.broad.mit.e...
Broad KEGG_PROTEASOME View Gene Set 6.202e-06 48 0.0001648 7 Proteasome www.broad.mit.e...
Broad KEGG_CELL_CYCLE View Gene Set 7.986e-06 128 0.0001857 8 Cell cycle www.broad.mit.e...
Broad KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS View Gene Set 2.335e-05 11 0.0004826 9 Valine leucine and isoleucine biosynthesis www.broad.mit.e...
Broad KEGG_MISMATCH_REPAIR View Gene Set 4.722e-05 23 0.0008783 10 Mismatch repair www.broad.mit.e...
Broad KEGG_LYSINE_DEGRADATION View Gene Set 9.831e-05 44 0.001662 11 Lysine degradation www.broad.mit.e...
Broad KEGG_CITRATE_CYCLE_TCA_CYCLE View Gene Set 0.000117 32 0.001814 12 Citrate cycle (TCA cycle) www.broad.mit.e...
Broad KEGG_RNA_POLYMERASE View Gene Set 0.0001509 29 0.002159 13 RNA polymerase www.broad.mit.e...
Broad KEGG_ONE_CARBON_POOL_BY_FOLATE View Gene Set 0.0003094 17 0.00411 14 One carbon pool by folate www.broad.mit.e...
Broad KEGG_GLYCOLYSIS_GLUCONEOGENESIS View Gene Set 0.0003559 62 0.004413 15 Glycolysis / Gluconeogenesis www.broad.mit.e...
Broad KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS View Gene Set 0.000802 140 0.009323 16 Systemic lupus erythematosus www.broad.mit.e...
Broad KEGG_CYSTEINE_AND_METHIONINE_METABOLISM View Gene Set 0.000997 34 0.01091 17 Cysteine and methionine metabolism www.broad.mit.e...
Broad KEGG_PYRUVATE_METABOLISM View Gene Set 0.001065 40 0.011 18 Pyruvate metabolism www.broad.mit.e...
Broad KEGG_PARKINSONS_DISEASE View Gene Set 0.001598 133 0.01565 19 Parkinson's disease www.broad.mit.e...
Broad KEGG_NUCLEOTIDE_EXCISION_REPAIR View Gene Set 0.001732 44 0.01611 20 Nucleotide excision repair www.broad.mit.e...
Broad KEGG_HUNTINGTONS_DISEASE View Gene Set 0.002843 185 0.02518 21 Huntington's disease www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.REACTOME

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad REACTOME_GENE_EXPRESSION View Gene Set 5.422e-33 415 2.331e-30 1 Genes involved in Gene Expression www.broad.mit.e...
Broad REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA View Gene Set 9.096e-31 128 1.956e-28 2 Genes involved in Processing of Capped Intron-Containing Pre-mRNA www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING View Gene Set 6.832e-23 97 9.793e-21 3 Genes involved in mRNA Splicing www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_RNA View Gene Set 7.371e-21 95 7.924e-19 4 Genes involved in Metabolism of RNA www.broad.mit.e...
Broad REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS View Gene Set 2.96e-20 124 2.546e-18 5 Genes involved in Elongation and Processing of Capped Transcripts www.broad.mit.e...
Broad REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT View Gene Set 2.338e-19 142 1.676e-17 6 Genes involved in Formation and Maturation of mRNA Transcript www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION View Gene Set 1.252e-16 188 7.688e-15 7 Genes involved in Transcription www.broad.mit.e...
Broad REACTOME_SNRNP_ASSEMBLY View Gene Set 3.812e-16 50 2.049e-14 8 Genes involved in snRNP Assembly www.broad.mit.e...
Broad REACTOME_MITOTIC_M_M_G1_PHASES View Gene Set 5.888e-16 157 2.813e-14 9 Genes involved in Mitotic M-M/G1 phases www.broad.mit.e...
Broad REACTOME_CELL_CYCLE_MITOTIC View Gene Set 1.865e-15 306 8.019e-14 10 Genes involved in Cell Cycle Mitotic www.broad.mit.e...
Broad REACTOME_TRNA_AMINOACYLATION View Gene Set 4.928e-14 40 1.926e-12 11 Genes involved in tRNA Aminoacylation www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRON_CONTAINING_TRANSCRIPT View Gene Set 3.948e-13 42 1.415e-11 12 Genes involved in Transport of Mature mRNA derived from an Intron-Containing Transcript www.broad.mit.e...
Broad REACTOME_TELOMERE_MAINTENANCE View Gene Set 2.665e-12 77 8.816e-11 13 Genes involved in Telomere Maintenance www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_III_AND_MITOCHONDRIAL_TRANSCRIPTION View Gene Set 2.636e-11 120 8.096e-10 14 Genes involved in RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription www.broad.mit.e...
Broad REACTOME_CELL_CYCLE_CHECKPOINTS View Gene Set 3.426e-11 110 9.822e-10 15 Genes involved in Cell Cycle Checkpoints www.broad.mit.e...
Broad REACTOME_REV_MEDIATED_NUCLEAR_EXPORT_OF_HIV1_RNA View Gene Set 5.244e-11 31 1.409e-09 16 Genes involved in Rev-mediated nuclear export of HIV-1 RNA www.broad.mit.e...
Broad REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN View Gene Set 1.67e-10 30 4.224e-09 17 Genes involved in Nuclear import of Rev protein www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_THE_SLBP_INDEPENDENT_MATURE_MRNA View Gene Set 2.472e-10 32 5.906e-09 18 Genes involved in Transport of the SLBP independent Mature mRNA www.broad.mit.e...
Broad REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY View Gene Set 4.821e-10 29 1.091e-08 19 Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery www.broad.mit.e...
Broad REACTOME_SYNTHESIS_OF_DNA View Gene Set 7.489e-10 89 1.61e-08 20 Genes involved in Synthesis of DNA www.broad.mit.e...
Broad REACTOME_MITOTIC_PROMETAPHASE View Gene Set 2.063e-09 92 4.224e-08 21 Genes involved in Mitotic Prometaphase www.broad.mit.e...
Broad REACTOME_HIV_LIFE_CYCLE View Gene Set 2.554e-09 103 4.991e-08 22 Genes involved in HIV Life Cycle www.broad.mit.e...
Broad REACTOME_VPR_MEDIATED_NUCLEAR_IMPORT_OF_PICS View Gene Set 2.694e-09 31 5.036e-08 23 Genes involved in Vpr-mediated nuclear import of PICs www.broad.mit.e...
Broad REACTOME_DNA_REPLICATION_PRE_INITIATION View Gene Set 3.913e-09 76 7.01e-08 24 Genes involved in DNA Replication Pre-Initiation www.broad.mit.e...
Broad REACTOME_HIV_INFECTION View Gene Set 4.084e-09 183 7.024e-08 25 Genes involved in HIV Infection www.broad.mit.e...
Broad REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION View Gene Set 5.435e-09 23 8.989e-08 26 Genes involved in Cytosolic tRNA aminoacylation www.broad.mit.e...
Broad REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE View Gene Set 8.754e-09 90 1.394e-07 27 Genes involved in Late Phase of HIV Life Cycle www.broad.mit.e...
Broad REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS View Gene Set 1.426e-08 29 2.19e-07 28 Genes involved in Transport of Ribonucleoproteins into the Host Nucleus www.broad.mit.e...
Broad REACTOME_S_PHASE View Gene Set 2.192e-08 103 3.25e-07 29 Genes involved in S Phase www.broad.mit.e...
Broad REACTOME_M_G1_TRANSITION View Gene Set 3.294e-08 61 4.682e-07 30 Genes involved in M/G1 Transition www.broad.mit.e...
Broad REACTOME_PACKAGING_OF_TELOMERE_ENDS View Gene Set 3.375e-08 49 4.682e-07 30 Genes involved in Packaging Of Telomere Ends www.broad.mit.e...
Broad REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION View Gene Set 3.92e-08 161 5.267e-07 32 Genes involved in Glucose Regulation of Insulin Secretion www.broad.mit.e...
Broad REACTOME_MRNA_3_END_PROCESSING View Gene Set 4.267e-08 25 5.56e-07 33 Genes involved in mRNA 3-end processing www.broad.mit.e...
Broad REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN View Gene Set 4.42e-08 29 5.59e-07 34 Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein www.broad.mit.e...
Broad REACTOME_PYRUVATE_METABOLISM_AND_TCA_CYCLE View Gene Set 4.591e-08 36 5.641e-07 35 Genes involved in Pyruvate metabolism and TCA cycle www.broad.mit.e...
Broad REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION View Gene Set 5.215e-08 20 6.229e-07 36 Genes involved in Mitochondrial tRNA aminoacylation www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_PROMOTER_OPENING View Gene Set 9.903e-08 59 1.151e-06 37 Genes involved in RNA Polymerase I Promoter Opening www.broad.mit.e...
Broad REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS View Gene Set 1.552e-07 120 1.756e-06 38 Genes involved in Host Interactions of HIV factors www.broad.mit.e...
Broad REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC View Gene Set 1.698e-07 57 1.872e-06 39 Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C www.broad.mit.e...
Broad REACTOME_CDC20_PHOSPHO_APC_MEDIATED_DEGRADATION_OF_CYCLIN_A View Gene Set 2.295e-07 63 2.467e-06 40 Genes involved in Cdc20:Phospho-APC/C mediated degradation of Cyclin A www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_AMINO_ACIDS View Gene Set 2.575e-07 162 2.664e-06 41 Genes involved in Metabolism of amino acids www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_PROMOTER_CLEARANCE View Gene Set 2.602e-07 82 2.664e-06 41 Genes involved in RNA PolymerasePromoter Clearance www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_MRNA View Gene Set 2.834e-07 45 2.834e-06 43 Genes involved in Metabolism of mRNA www.broad.mit.e...
Broad REACTOME_GLUCOSE_TRANSPORT View Gene Set 3.415e-07 38 3.337e-06 44 Genes involved in Glucose transport www.broad.mit.e...
Broad REACTOME_MRNA_SPLICING_MINOR_PATHWAY View Gene Set 5.314e-07 38 4.967e-06 45 Genes involved in mRNA Splicing - Minor Pathway www.broad.mit.e...
Broad REACTOME_REGULATION_OF_APC_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE View Gene Set 5.295e-07 71 4.967e-06 45 Genes involved in Regulation of APC/C activators between G1/S and early anaphase www.broad.mit.e...
Broad REACTOME_ORC1_REMOVAL_FROM_CHROMATIN View Gene Set 6.211e-07 63 5.683e-06 47 Genes involved in Orc1 removal from chromatin www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_CARBOHYDRATES View Gene Set 6.786e-07 119 6.08e-06 48 Genes involved in Metabolism of carbohydrates www.broad.mit.e...
Broad REACTOME_G2_M_CHECKPOINTS View Gene Set 7.784e-07 43 6.831e-06 49 Genes involved in G2/M Checkpoints www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION View Gene Set 8.417e-07 83 7.239e-06 50 Genes involved in RNA Polymerase II Transcription www.broad.mit.e...
Broad REACTOME_DNA_REPAIR View Gene Set 1.035e-06 102 8.73e-06 51 Genes involved in DNA Repair www.broad.mit.e...
Broad REACTOME_TRANSLATION View Gene Set 1.266e-06 120 1.047e-05 52 Genes involved in Translation www.broad.mit.e...
Broad REACTOME_G1_S_TRANSITION View Gene Set 1.382e-06 102 1.121e-05 53 Genes involved in G1/S Transition www.broad.mit.e...
Broad REACTOME_INFLUENZA_LIFE_CYCLE View Gene Set 2.405e-06 137 1.915e-05 54 Genes involved in Influenza Life Cycle www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS View Gene Set 5.161e-06 37 3.969e-05 55 Genes involved in Activation of ATR in response to replication stress www.broad.mit.e...
Broad REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 View Gene Set 5.169e-06 48 3.969e-05 55 Genes involved in SCF-beta-TrCP mediated degradation of Emi1 www.broad.mit.e...
Broad REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE View Gene Set 5.339e-06 43 4.028e-05 57 Genes involved in p53-Independent DNA Damage Response www.broad.mit.e...
Broad REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX View Gene Set 5.797e-06 52 4.297e-05 58 Genes involved in CDT1 association with the CDC6:ORC:origin complex www.broad.mit.e...
Broad REACTOME_DNA_STRAND_ELONGATION View Gene Set 7.998e-06 31 5.829e-05 59 Genes involved in DNA strand elongation www.broad.mit.e...
Broad REACTOME_EXTENSION_OF_TELOMERES View Gene Set 9.066e-06 28 6.483e-05 60 Genes involved in Extension of Telomeres www.broad.mit.e...
Broad REACTOME_STABILIZATION_OF_P53 View Gene Set 9.197e-06 46 6.483e-05 60 Genes involved in Stabilization of p53 www.broad.mit.e...
Broad REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G View Gene Set 1.398e-05 47 9.699e-05 62 Genes involved in Vif-mediated degradation of APOBEC3G www.broad.mit.e...
Broad REACTOME_MICRORNA_BIOGENESIS View Gene Set 2.065e-05 18 0.0001409 63 Genes involved in MicroRNA biogenesis www.broad.mit.e...
Broad REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION View Gene Set 2.132e-05 56 0.0001432 64 Genes involved in Translation initiation complex formation www.broad.mit.e...
Broad REACTOME_INTEGRATION_OF_ENERGY_METABOLISM View Gene Set 2.671e-05 229 0.0001767 65 Genes involved in Integration of energy metabolism www.broad.mit.e...
Broad REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE View Gene Set 2.971e-05 47 0.0001936 66 Genes involved in Regulation of ornithine decarboxylase (ODC) www.broad.mit.e...
Broad REACTOME_PYRUVATE_METABOLISM View Gene Set 5.07e-05 18 0.0003254 67 Genes involved in Pyruvate metabolism www.broad.mit.e...
Broad REACTOME_SIGNALING_BY_WNT View Gene Set 6.039e-05 58 0.0003819 68 Genes involved in Signaling by Wnt www.broad.mit.e...
Broad REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX View Gene Set 6.274e-05 30 0.0003854 69 Genes involved in Activation of the pre-replicative complex www.broad.mit.e...
Broad REACTOME_CITRIC_ACID_CYCLE View Gene Set 6.214e-05 19 0.0003854 69 Genes involved in Citric acid cycle (TCA cycle) www.broad.mit.e...
Broad REACTOME_NUCLEOTIDE_EXCISION_REPAIR View Gene Set 8.018e-05 49 0.0004856 71 Genes involved in Nucleotide Excision Repair www.broad.mit.e...
Broad REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR View Gene Set 0.0001168 15 0.0006974 72 Genes involved in Homologous Recombination Repair www.broad.mit.e...
Broad REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS View Gene Set 0.0001184 11 0.0006974 72 Genes involved in Purine ribonucleoside monophosphate biosynthesis www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER View Gene Set 0.0001201 20 0.0006979 74 Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter www.broad.mit.e...
Broad REACTOME_UNWINDING_OF_DNA View Gene Set 0.0001668 11 0.0009565 75 Genes involved in Unwinding of DNA www.broad.mit.e...
Broad REACTOME_DOUBLE_STRAND_BREAK_REPAIR View Gene Set 0.0001692 21 0.0009573 76 Genes involved in Double-Strand Break Repair www.broad.mit.e...
Broad REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21 View Gene Set 0.0001771 52 0.000989 77 Genes involved in SCF(Skp2)-mediated degradation of p2721 www.broad.mit.e...
Broad REACTOME_ELECTRON_TRANSPORT_CHAIN View Gene Set 0.0002035 75 0.001122 78 Genes involved in Electron Transport Chain www.broad.mit.e...
Broad REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT View Gene Set 0.0002254 106 0.001227 79 Genes involved in GTP hydrolysis and joining of the 60S ribosomal subunit www.broad.mit.e...
Broad REACTOME_METABLISM_OF_NUCLEOTIDES View Gene Set 0.0002959 71 0.001591 80 Genes involved in Metablism of nucleotides www.broad.mit.e...
Broad REACTOME_REGULATION_OF_INSULIN_SECRETION View Gene Set 0.0004717 212 0.002504 81 Genes involved in Regulation of Insulin Secretion www.broad.mit.e...
Broad REACTOME_METABOLISM_OF_PROTEINS View Gene Set 0.0005243 215 0.002749 82 Genes involved in Metabolism of proteins www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_TERMINATION View Gene Set 0.0006131 17 0.003176 83 Genes involved in RNA Polymerase III Transcription Termination www.broad.mit.e...
Broad REACTOME_DEADENYLATION_OF_MRNA View Gene Set 0.0007424 21 0.0038 84 Genes involved in Deadenylation of mRNA www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION View Gene Set 0.0009869 34 0.004992 85 Genes involved in RNA Polymerase III Transcription www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION_COUPLED_NER View Gene Set 0.001146 44 0.005732 86 Genes involved in Transcription-coupled NER (TC-NER) www.broad.mit.e...
Broad REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE View Gene Set 0.001231 11 0.006082 87 Genes involved in mRNA Decay by 3' to 5' Exoribonuclease www.broad.mit.e...
Broad REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX View Gene Set 0.001386 49 0.006748 88 Genes involved in Formation of the ternary complex and subsequently the 43S complex www.broad.mit.e...
Broad REACTOME_GLUCONEOGENESIS View Gene Set 0.001397 31 0.006748 88 Genes involved in Gluconeogenesis www.broad.mit.e...
Broad REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS View Gene Set 0.001536 29 0.007338 90 Genes involved in Association of TriC/CCT with target proteins during biosynthesis www.broad.mit.e...
Broad REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ View Gene Set 0.001951 58 0.009217 91 Genes involved in Cyclin E associated events during G1/S transition www.broad.mit.e...
Broad REACTOME_REPAIR_SYNTHESIS_OF_PATCH_27_30_BASES_LONG_BY_DNA_POLYMERASE View Gene Set 0.002394 15 0.01119 92 Genes involved in Repair synthesis of patch ~27-30 bases long by DNA polymerase www.broad.mit.e...
Broad REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT View Gene Set 0.002489 23 0.01151 93 Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat www.broad.mit.e...
Broad REACTOME_INACTIVATION_OF_APC_VIA_DIRECT_INHIBITION_OF_THE_APCOMPLEX View Gene Set 0.002902 18 0.01327 94 Genes involved in Inactivation of APC/C via direct inhibition of the APC/C complex www.broad.mit.e...
Broad REACTOME_GLOBAL_GENOMIC_NER View Gene Set 0.00295 33 0.01335 95 Genes involved in Global Genomic NER (GG-NER) www.broad.mit.e...
Broad REACTOME_CONVERSION_FROM_APC_CDC20_TO_APC_CDH1_IN_LATE_ANAPHASE View Gene Set 0.003045 17 0.01364 96 Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase www.broad.mit.e...
Broad REACTOME_MTORC1_MEDIATED_SIGNALLING View Gene Set 0.003341 11 0.01481 97 Genes involved in mTORC1-mediated signalling www.broad.mit.e...
Broad REACTOME_BASE_EXCISION_REPAIR View Gene Set 0.003741 18 0.01625 98 Genes involved in Base Excision Repair www.broad.mit.e...
Broad REACTOME_PYRIMIDINE_METABOLISM View Gene Set 0.003724 22 0.01625 98 Genes involved in Pyrimidine metabolism www.broad.mit.e...
Broad REACTOME_LAGGING_STRAND_SYNTHESIS View Gene Set 0.0038 20 0.01634 100 Genes involved in Lagging Strand Synthesis www.broad.mit.e...
Broad REACTOME_VITAMIN_B5_(PANTOTHENATE)_METABOLISM View Gene Set 0.003885 11 0.01654 101 Genes involved in Vitamin B5 (pantothenate) metabolism www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_CHAIN_ELONGATION View Gene Set 0.004523 12 0.01907 102 Genes involved in RNA Polymerase III Chain Elongation www.broad.mit.e...
Broad REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING View Gene Set 0.004818 15 0.02012 103 Genes involved in Formation of ATP by chemiosmotic coupling www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION View Gene Set 0.005494 29 0.02272 104 Genes involved in RNA Polymerase III Transcription Initiation www.broad.mit.e...
Broad REACTOME_REMOVAL_OF_DNA_PATCH_CONTAINING_ABASIC_RESIDUE View Gene Set 0.005804 15 0.02377 105 Genes involved in Removal of DNA patch containing abasic residue www.broad.mit.e...
Broad REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_COMPLEX View Gene Set 0.006264 12 0.02541 106 Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex www.broad.mit.e...
Broad REACTOME_APCDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B View Gene Set 0.00654 18 0.02604 107 Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B www.broad.mit.e...
Broad REACTOME_PHOSPHORYLATION_OF_THE_APC View Gene Set 0.006495 17 0.02604 107 Genes involved in Phosphorylation of the APC/C www.broad.mit.e...
Broad REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE View Gene Set 0.006894 13 0.0272 109 Genes involved in mRNA Decay by 5' to 3' Exoribonuclease www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME View Gene Set 0.01062 59 0.0415 110 Genes involved in Transcription of the HIV genome www.broad.mit.e...
Broad REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS View Gene Set 0.01198 95 0.04599 111 Genes involved in Formation of a pool of free 40S subunits www.broad.mit.e...
Broad REACTOME_TAT_MEDIATED_HIV1_ELONGATION_ARREST_AND_RECOVERY View Gene Set 0.01195 30 0.04599 111 Genes involved in Tat-mediated HIV-1 elongation arrest and recovery www.broad.mit.e...
Broad REACTOME_GLUCOSE_METABOLISM View Gene Set 0.01307 56 0.04973 113 Genes involved in Glucose metabolism www.broad.mit.e...

Gene Set Collection: Broad.c3.TFT

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad GCCATNTTG_V$YY1_Q6 View Gene Set 3.594e-13 289 2.21e-10 1 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTG which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad CACGTG_V$MYC_Q2 View Gene Set 8.583e-12 734 2.639e-09 2 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CACGTG which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian) www.broad.mit.e...
Broad V$E2F_Q4_01 View Gene Set 8.568e-10 171 1.756e-07 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCSCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F_Q3 View Gene Set 3.93e-09 162 6.043e-07 4 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTCGCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad SGCGSSAAA_V$E2F1DP2_01 View Gene Set 1.308e-08 122 1.608e-06 5 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SGCGSSAAA which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) www.broad.mit.e...
Broad V$MYCMAX_01 View Gene Set 1.976e-08 189 2.025e-06 6 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNACCACGTGGTNN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X www.broad.mit.e...
Broad V$E2F1_Q6_01 View Gene Set 4.916e-08 177 4.319e-06 7 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTTCGCGCS which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F1_Q4_01 View Gene Set 9.517e-08 167 7.317e-06 8 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F_Q4 View Gene Set 1.264e-07 166 8.638e-06 9 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MAX_01 View Gene Set 1.913e-07 194 9.804e-06 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNANCACGTGNTNN which matches annotation for MAX: MYC associated factor X www.broad.mit.e...
Broad V$E2F_Q6 View Gene Set 1.82e-07 165 9.804e-06 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1_Q3 View Gene Set 1.811e-07 176 9.804e-06 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKTSSCGC which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F_03 View Gene Set 2.57e-07 171 1.216e-05 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGCGMNR. Motif does not match any known transcription factor www.broad.mit.e...
Broad KRCTCNNNNMANAGC_UNKNOWN View Gene Set 5.358e-07 60 2.354e-05 14 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KRCTCNNNNMANAGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1DP1RB_01 View Gene Set 6.003e-07 168 2.461e-05 15 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) www.broad.mit.e...
Broad V$E2F_Q6_01 View Gene Set 8.767e-07 167 3.37e-05 16 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKCGCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F_Q3_01 View Gene Set 1.057e-06 171 3.824e-05 17 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1_Q6 View Gene Set 1.942e-06 167 6.634e-05 18 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGS which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$E2F_02 View Gene Set 3.455e-06 169 0.0001118 19 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGC. Motif does not match any known transcription factor www.broad.mit.e...
Broad RRCCGTTA_UNKNOWN View Gene Set 3.668e-06 53 0.0001128 20 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif RRCCGTTA. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$YY1_Q6 View Gene Set 4.033e-06 166 0.0001181 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTN which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...
Broad SCGGAAGY_V$ELK1_02 View Gene Set 4.99e-06 784 0.0001395 22 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SCGGAAGY which matches annotation for ELK1: ELK1 member of ETS oncogene family www.broad.mit.e...
Broad GCGSCMNTTT_UNKNOWN View Gene Set 6.732e-06 49 0.00018 23 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GCGSCMNTTT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F4DP1_01 View Gene Set 8.388e-06 174 0.0002149 24 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1DP1_01 View Gene Set 1.065e-05 169 0.0002427 25 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1 www.broad.mit.e...
Broad V$E2F1DP2_01 View Gene Set 1.065e-05 169 0.0002427 25 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) www.broad.mit.e...
Broad V$E2F4DP2_01 View Gene Set 1.065e-05 169 0.0002427 25 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) www.broad.mit.e...
Broad ACAWNRNSRCGG_UNKNOWN View Gene Set 1.484e-05 50 0.0003148 28 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ACAWNRNSRCGG. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$NFMUE1_Q6 View Gene Set 1.464e-05 175 0.0003148 28 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CGGCCATCT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$NMYC_01 View Gene Set 1.82e-05 201 0.0003731 30 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNCCACGTGNNN which matches annotation for MYCN: v-myc myelocytomatosis viral related oncogene neuroblastoma derived (avian) www.broad.mit.e...
Broad V$USF_01 View Gene Set 5.013e-05 186 0.0009945 31 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNRYCACGTGRYNN. Motif does not match any known transcription factor www.broad.mit.e...
Broad GKCGCNNNNNNNTGAYG_UNKNOWN View Gene Set 7.544e-05 41 0.00145 32 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GKCGCNNNNNNNTGAYG. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MYCMAX_03 View Gene Set 0.0001008 187 0.001879 33 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNNNCACGTGNNNNNNN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X www.broad.mit.e...
Broad KCCGNSWTTT_UNKNOWN View Gene Set 0.0001411 76 0.002552 34 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KCCGNSWTTT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$ARNT_01 View Gene Set 0.000189 196 0.003321 35 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NDDNNCACGTGNNNNN which matches annotation for ARNT: aryl hydrocarbon receptor nuclear translocator www.broad.mit.e...
Broad V$E2F1_Q4 View Gene Set 0.0002413 178 0.00401 36 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTSGCGG which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad GGCNKCCATNK_UNKNOWN View Gene Set 0.0002409 84 0.00401 36 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGCNKCCATNK. Motif does not match any known transcription factor www.broad.mit.e...
Broad RCGCANGCGY_V$NRF1_Q6 View Gene Set 0.0002523 580 0.004084 38 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RCGCANGCGY which matches annotation for NRF1: nuclear respiratory factor 1 www.broad.mit.e...
Broad TAANNYSGCG_UNKNOWN View Gene Set 0.0006051 60 0.009543 39 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TAANNYSGCG. Motif does not match any known transcription factor www.broad.mit.e...
Broad KTGGYRSGAA_UNKNOWN View Gene Set 0.0006314 53 0.009708 40 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KTGGYRSGAA. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$USF_C View Gene Set 0.0006672 211 0.01001 41 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NCACGTGN. Motif does not match any known transcription factor www.broad.mit.e...
Broad TMTCGCGANR_UNKNOWN View Gene Set 0.001319 100 0.01932 42 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TMTCGCGANR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$E2F1_Q3_01 View Gene Set 0.0015 188 0.02145 43 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTGGCGCGRAANNGNM which matches annotation for E2F1: E2F transcription factor 1 www.broad.mit.e...
Broad V$ELK1_02 View Gene Set 0.002156 170 0.03013 44 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNCCGGAARTNN which matches annotation for ELK1: ELK1 member of ETS oncogene family www.broad.mit.e...
Broad AACYNNNNTTCCS_UNKNOWN View Gene Set 0.002457 65 0.03345 45 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif AACYNNNNTTCCS. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MYCMAX_B View Gene Set 0.002502 193 0.03345 45 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCAYGYGSN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X www.broad.mit.e...
Broad V$E2F_01 View Gene Set 0.002602 55 0.03405 47 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TWSGCGCGAAAAYKR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$GATA1_01 View Gene Set 0.003241 178 0.04152 48 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SNNGATNNNN which matches annotation for GATA1: GATA binding protein 1 (globin transcription factor 1) www.broad.mit.e...
Broad V$YY1_02 View Gene Set 0.003827 168 0.04803 49 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNCGGCCATCTTGNCTSNW which matches annotation for YY1: YY1 transcription factor www.broad.mit.e...

Gene Set Collection: Broad.c4.CGN

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad MORF_BUB3 View Gene Set 4.513e-41 256 1.927e-38 1 Neighborhood of BUB3 www.broad.mit.e...
Broad MORF_EIF3S2 View Gene Set 1.624e-39 220 3.467e-37 2 Neighborhood of EIF3S2 www.broad.mit.e...
Broad MORF_RAD23A View Gene Set 4.207e-35 316 5.988e-33 3 Neighborhood of RAD23A www.broad.mit.e...
Broad MORF_HDAC2 View Gene Set 1.755e-34 256 1.873e-32 4 Neighborhood of HDAC2 www.broad.mit.e...
Broad MORF_FBL View Gene Set 2.293e-33 121 1.958e-31 5 Neighborhood of FBL www.broad.mit.e...
Broad MORF_PRKDC View Gene Set 7.004e-29 173 4.985e-27 6 Neighborhood of PRKDC www.broad.mit.e...
Broad MORF_AATF View Gene Set 1.025e-27 179 6.251e-26 7 Neighborhood of AATF www.broad.mit.e...
Broad MORF_RFC4 View Gene Set 2.826e-26 137 1.508e-24 8 Neighborhood of RFC4 www.broad.mit.e...
Broad MORF_DEK View Gene Set 4.964e-26 229 2.355e-24 9 Neighborhood of DEK www.broad.mit.e...
Broad MORF_PPP1CC View Gene Set 5.973e-24 150 2.55e-22 10 Neighborhood of PPP1CC www.broad.mit.e...
Broad GNF2_PA2G4 View Gene Set 4.098e-23 73 1.591e-21 11 Neighborhood of PA2G4 www.broad.mit.e...
Broad MORF_UBE2I View Gene Set 5.128e-23 208 1.825e-21 12 Neighborhood of UBE2I www.broad.mit.e...
Broad MORF_CSNK2B View Gene Set 1.134e-22 256 3.726e-21 13 Neighborhood of CSNK2B www.broad.mit.e...
Broad MORF_HAT1 View Gene Set 3.776e-22 155 1.152e-20 14 Neighborhood of HAT1 www.broad.mit.e...
Broad MORF_SOD1 View Gene Set 2.343e-21 247 6.67e-20 15 Neighborhood of SOD1 www.broad.mit.e...
Broad MORF_RAN View Gene Set 5.789e-21 242 1.545e-19 16 Neighborhood of RAN www.broad.mit.e...
Broad GNF2_RRM1 View Gene Set 6.21e-21 82 1.56e-19 17 Neighborhood of RRM1 www.broad.mit.e...
Broad MORF_ANP32B View Gene Set 9.197e-21 174 2.182e-19 18 Neighborhood of ANP32B www.broad.mit.e...
Broad MORF_DNMT1 View Gene Set 1.547e-20 105 3.477e-19 19 Neighborhood of DNMT1 www.broad.mit.e...
Broad MORF_G22P1 View Gene Set 1.702e-20 145 3.633e-19 20 Neighborhood of G22P1 www.broad.mit.e...
Broad MORF_XRCC5 View Gene Set 2.002e-20 210 4.071e-19 21 Neighborhood of XRCC5 www.broad.mit.e...
Broad MORF_ACP1 View Gene Set 3.616e-20 178 7.018e-19 22 Neighborhood of ACP1 www.broad.mit.e...
Broad GNF2_RAN View Gene Set 4.305e-20 78 7.992e-19 23 Neighborhood of RAN www.broad.mit.e...
Broad GNF2_SMC4L1 View Gene Set 1.671e-18 75 2.972e-17 24 Neighborhood of SMC4L1 www.broad.mit.e...
Broad GNF2_APEX1 View Gene Set 1.859e-18 72 3.175e-17 25 Neighborhood of APEX1 www.broad.mit.e...
Broad MORF_PCNA View Gene Set 2.009e-18 71 3.3e-17 26 Neighborhood of PCNA www.broad.mit.e...
Broad MORF_RAD54L View Gene Set 4.081e-18 94 6.454e-17 27 Neighborhood of RAD54L www.broad.mit.e...
Broad GNF2_RFC4 View Gene Set 4.482e-18 57 6.835e-17 28 Neighborhood of RFC4 www.broad.mit.e...
Broad MORF_RRM1 View Gene Set 6.236e-18 90 9.182e-17 29 Neighborhood of RRM1 www.broad.mit.e...
Broad MORF_GNB1 View Gene Set 1.317e-16 276 1.874e-15 30 Neighborhood of GNB1 www.broad.mit.e...
Broad GNF2_NPM1 View Gene Set 2.713e-16 57 3.737e-15 31 Neighborhood of NPM1 www.broad.mit.e...
Broad GNF2_FBL View Gene Set 8.796e-16 119 1.174e-14 32 Neighborhood of FBL www.broad.mit.e...
Broad GNF2_MCM4 View Gene Set 1.03e-15 50 1.333e-14 33 Neighborhood of MCM4 www.broad.mit.e...
Broad MORF_DEAF1 View Gene Set 1.455e-15 54 1.827e-14 34 Neighborhood of DEAF1 www.broad.mit.e...
Broad GNF2_DEK View Gene Set 1.893e-15 45 2.309e-14 35 Neighborhood of DEK www.broad.mit.e...
Broad MORF_HDAC1 View Gene Set 2.488e-15 222 2.95e-14 36 Neighborhood of HDAC1 www.broad.mit.e...
Broad GNF2_PCNA View Gene Set 2.98e-15 62 3.439e-14 37 Neighborhood of PCNA www.broad.mit.e...
Broad GCM_APEX1 View Gene Set 4.871e-15 102 5.473e-14 38 Neighborhood of APEX1 www.broad.mit.e...
Broad MORF_UNG View Gene Set 1.623e-14 65 1.776e-13 39 Neighborhood of UNG www.broad.mit.e...
Broad GNF2_NS View Gene Set 1.929e-14 35 2.06e-13 40 Neighborhood of NS www.broad.mit.e...
Broad GNF2_MCM5 View Gene Set 3.405e-14 51 3.546e-13 41 Neighborhood of MCM5 www.broad.mit.e...
Broad GNF2_BUB1B View Gene Set 6.52e-14 46 6.629e-13 42 Neighborhood of BUB1B www.broad.mit.e...
Broad GNF2_KPNB1 View Gene Set 7.922e-14 52 7.867e-13 43 Neighborhood of KPNB1 www.broad.mit.e...
Broad GNF2_CENPF View Gene Set 8.937e-14 56 8.673e-13 44 Neighborhood of CENPF www.broad.mit.e...
Broad GNF2_CCNA2 View Gene Set 1.093e-13 62 1.037e-12 45 Neighborhood of CCNA2 www.broad.mit.e...
Broad MORF_MSH2 View Gene Set 1.143e-13 52 1.038e-12 46 Neighborhood of MSH2 www.broad.mit.e...
Broad MORF_DAP3 View Gene Set 1.128e-13 175 1.038e-12 46 Neighborhood of DAP3 www.broad.mit.e...
Broad GNF2_MLH1 View Gene Set 3.179e-13 36 2.828e-12 48 Neighborhood of MLH1 www.broad.mit.e...
Broad MORF_UBE2N View Gene Set 6.351e-13 79 5.534e-12 49 Neighborhood of UBE2N www.broad.mit.e...
Broad GNF2_RBBP6 View Gene Set 6.74e-13 54 5.756e-12 50 Neighborhood of RBBP6 www.broad.mit.e...
Broad MORF_EIF4E View Gene Set 1.919e-12 76 1.607e-11 51 Neighborhood of EIF4E www.broad.mit.e...
Broad GNF2_HAT1 View Gene Set 2.867e-12 45 2.342e-11 52 Neighborhood of HAT1 www.broad.mit.e...
Broad GNF2_MSH6 View Gene Set 2.907e-12 30 2.342e-11 52 Neighborhood of MSH6 www.broad.mit.e...
Broad GNF2_HDAC1 View Gene Set 3.096e-12 85 2.448e-11 54 Neighborhood of HDAC1 www.broad.mit.e...
Broad GNF2_RRM2 View Gene Set 3.386e-12 36 2.628e-11 55 Neighborhood of RRM2 www.broad.mit.e...
Broad MORF_SMC1L1 View Gene Set 3.733e-12 47 2.797e-11 56 Neighborhood of SMC1L1 www.broad.mit.e...
Broad GNF2_DENR View Gene Set 3.73e-12 39 2.797e-11 56 Neighborhood of DENR www.broad.mit.e...
Broad MORF_FEN1 View Gene Set 4.062e-12 58 2.991e-11 58 Neighborhood of FEN1 www.broad.mit.e...
Broad MORF_ESPL1 View Gene Set 5.111e-12 58 3.699e-11 59 Neighborhood of ESPL1 www.broad.mit.e...
Broad MORF_CDC16 View Gene Set 5.552e-12 67 3.951e-11 60 Neighborhood of CDC16 www.broad.mit.e...
Broad MORF_ERH View Gene Set 5.969e-12 103 4.178e-11 61 Neighborhood of ERH www.broad.mit.e...
Broad MORF_RAD21 View Gene Set 6.556e-12 157 4.515e-11 62 Neighborhood of RAD21 www.broad.mit.e...
Broad MORF_PPP2CA View Gene Set 1.883e-11 110 1.276e-10 63 Neighborhood of PPP2CA www.broad.mit.e...
Broad GNF2_HMMR View Gene Set 2.046e-11 43 1.365e-10 64 Neighborhood of HMMR www.broad.mit.e...
Broad MORF_PTPN11 View Gene Set 2.117e-11 93 1.377e-10 65 Neighborhood of PTPN11 www.broad.mit.e...
Broad GNF2_MSH2 View Gene Set 2.128e-11 26 1.377e-10 65 Neighborhood of MSH2 www.broad.mit.e...
Broad GNF2_CDC20 View Gene Set 2.773e-11 52 1.767e-10 67 Neighborhood of CDC20 www.broad.mit.e...
Broad MORF_GMPS View Gene Set 2.959e-11 48 1.825e-10 68 Neighborhood of GMPS www.broad.mit.e...
Broad GCM_ACTG1 View Gene Set 3.035e-11 113 1.825e-10 68 Neighborhood of ACTG1 www.broad.mit.e...
Broad GNF2_CCNB2 View Gene Set 3.015e-11 53 1.825e-10 68 Neighborhood of CCNB2 www.broad.mit.e...
Broad GNF2_CKS1B View Gene Set 2.973e-11 36 1.825e-10 68 Neighborhood of CKS1B www.broad.mit.e...
Broad MORF_MAP2K2 View Gene Set 3.183e-11 123 1.888e-10 72 Neighborhood of MAP2K2 www.broad.mit.e...
Broad MORF_BUB1B View Gene Set 3.264e-11 61 1.909e-10 73 Neighborhood of BUB1B www.broad.mit.e...
Broad MORF_EI24 View Gene Set 3.411e-11 136 1.968e-10 74 Neighborhood of EI24 www.broad.mit.e...
Broad GNF2_RFC3 View Gene Set 4.16e-11 38 2.368e-10 75 Neighborhood of RFC3 www.broad.mit.e...
Broad GNF2_CDC2 View Gene Set 4.772e-11 56 2.681e-10 76 Neighborhood of CDC2 www.broad.mit.e...
Broad GNF2_ESPL1 View Gene Set 5.204e-11 35 2.886e-10 77 Neighborhood of ESPL1 www.broad.mit.e...
Broad GNF2_FEN1 View Gene Set 9.29e-11 49 5.086e-10 78 Neighborhood of FEN1 www.broad.mit.e...
Broad MORF_CUL1 View Gene Set 1.006e-10 62 5.437e-10 79 Neighborhood of CUL1 www.broad.mit.e...
Broad GCM_PPP1CC View Gene Set 1.452e-10 47 7.752e-10 80 Neighborhood of PPP1CC www.broad.mit.e...
Broad GNF2_G22P1 View Gene Set 1.937e-10 29 1.021e-09 81 Neighborhood of G22P1 www.broad.mit.e...
Broad GCM_CBFB View Gene Set 4.805e-10 59 2.502e-09 82 Neighborhood of CBFB www.broad.mit.e...
Broad GNF2_XRCC5 View Gene Set 4.937e-10 61 2.54e-09 83 Neighborhood of XRCC5 www.broad.mit.e...
Broad MORF_SART1 View Gene Set 6.125e-10 55 3.114e-09 84 Neighborhood of SART1 www.broad.mit.e...
Broad MORF_EIF3S6 View Gene Set 6.733e-10 108 3.383e-09 85 Neighborhood of EIF3S6 www.broad.mit.e...
Broad MORF_RPA1 View Gene Set 8.905e-10 55 4.421e-09 86 Neighborhood of RPA1 www.broad.mit.e...
Broad MORF_DDB1 View Gene Set 1.252e-09 220 6.144e-09 87 Neighborhood of DDB1 www.broad.mit.e...
Broad GNF2_TDG View Gene Set 1.518e-09 23 7.365e-09 88 Neighborhood of TDG www.broad.mit.e...
Broad MORF_RPA2 View Gene Set 1.62e-09 170 7.771e-09 89 Neighborhood of RPA2 www.broad.mit.e...
Broad GCM_NPM1 View Gene Set 3.193e-09 108 1.515e-08 90 Neighborhood of NPM1 www.broad.mit.e...
Broad MORF_PHB View Gene Set 3.421e-09 112 1.605e-08 91 Neighborhood of PHB www.broad.mit.e...
Broad GNF2_CENPE View Gene Set 3.532e-09 37 1.639e-08 92 Neighborhood of CENPE www.broad.mit.e...
Broad MORF_BUB1 View Gene Set 4.243e-09 49 1.948e-08 93 Neighborhood of BUB1 www.broad.mit.e...
Broad MORF_CTBP1 View Gene Set 6.429e-09 149 2.92e-08 94 Neighborhood of CTBP1 www.broad.mit.e...
Broad MORF_TERF1 View Gene Set 6.566e-09 57 2.951e-08 95 Neighborhood of TERF1 www.broad.mit.e...
Broad MORF_GSPT1 View Gene Set 7.494e-09 41 3.333e-08 96 Neighborhood of GSPT1 www.broad.mit.e...
Broad GNF2_ANP32B View Gene Set 1.149e-08 29 5.057e-08 97 Neighborhood of ANP32B www.broad.mit.e...
Broad GCM_CSNK2B View Gene Set 2.535e-08 88 1.093e-07 98 Neighborhood of CSNK2B www.broad.mit.e...
Broad GNF2_TTK View Gene Set 2.525e-08 34 1.093e-07 98 Neighborhood of TTK www.broad.mit.e...
Broad GNF2_DAP3 View Gene Set 2.584e-08 98 1.103e-07 100 Neighborhood of DAP3 www.broad.mit.e...
Broad GNF2_SMC2L1 View Gene Set 3.43e-08 30 1.45e-07 101 Neighborhood of SMC2L1 www.broad.mit.e...
Broad MORF_CDK2 View Gene Set 4.372e-08 63 1.83e-07 102 Neighborhood of CDK2 www.broad.mit.e...
Broad GNF2_ELAC2 View Gene Set 4.482e-08 32 1.858e-07 103 Neighborhood of ELAC2 www.broad.mit.e...
Broad MORF_USP5 View Gene Set 4.721e-08 46 1.938e-07 104 Neighborhood of USP5 www.broad.mit.e...
Broad GNF2_CKS2 View Gene Set 5.7e-08 45 2.318e-07 105 Neighborhood of CKS2 www.broad.mit.e...
Broad GNF2_MKI67 View Gene Set 9.018e-08 26 3.633e-07 106 Neighborhood of MKI67 www.broad.mit.e...
Broad MORF_MTA1 View Gene Set 1.179e-07 95 4.706e-07 107 Neighborhood of MTA1 www.broad.mit.e...
Broad GCM_PSME1 View Gene Set 1.296e-07 76 5.124e-07 108 Neighborhood of PSME1 www.broad.mit.e...
Broad MORF_PRKAG1 View Gene Set 1.406e-07 202 5.506e-07 109 Neighborhood of PRKAG1 www.broad.mit.e...
Broad MORF_RAF1 View Gene Set 1.439e-07 94 5.585e-07 110 Neighborhood of RAF1 www.broad.mit.e...
Broad GNF2_UBE2I View Gene Set 1.571e-07 33 6.044e-07 111 Neighborhood of UBE2I www.broad.mit.e...
Broad GNF2_BUB1 View Gene Set 1.799e-07 25 6.86e-07 112 Neighborhood of BUB1 www.broad.mit.e...
Broad MORF_NPM1 View Gene Set 2.858e-07 152 1.08e-06 113 Neighborhood of NPM1 www.broad.mit.e...
Broad MORF_PPP1CA View Gene Set 3.989e-07 145 1.494e-06 114 Neighborhood of PPP1CA www.broad.mit.e...
Broad GNF2_SMC1L1 View Gene Set 4.124e-07 24 1.531e-06 115 Neighborhood of SMC1L1 www.broad.mit.e...
Broad MORF_CDC10 View Gene Set 5.067e-07 120 1.865e-06 116 Neighborhood of CDC10 www.broad.mit.e...
Broad GCM_RAF1 View Gene Set 6.953e-07 34 2.538e-06 117 Neighborhood of RAF1 www.broad.mit.e...
Broad GNF2_H2AFX View Gene Set 7.612e-07 28 2.755e-06 118 Neighborhood of H2AFX www.broad.mit.e...
Broad MORF_SKP1A View Gene Set 8.537e-07 175 3.063e-06 119 Neighborhood of SKP1A www.broad.mit.e...
Broad GCM_ANP32B View Gene Set 1.005e-06 32 3.574e-06 120 Neighborhood of ANP32B www.broad.mit.e...
Broad GCM_DDX5 View Gene Set 1.1e-06 52 3.882e-06 121 Neighborhood of DDX5 www.broad.mit.e...
Broad MORF_CCNF View Gene Set 1.68e-06 65 5.881e-06 122 Neighborhood of CCNF www.broad.mit.e...
Broad GNF2_RPA1 View Gene Set 3.352e-06 20 1.164e-05 123 Neighborhood of RPA1 www.broad.mit.e...
Broad GNF2_PPP6C View Gene Set 5.101e-06 33 1.757e-05 124 Neighborhood of PPP6C www.broad.mit.e...
Broad GCM_MAX View Gene Set 5.204e-06 28 1.778e-05 125 Neighborhood of MAX www.broad.mit.e...
Broad MORF_CCNI View Gene Set 1.026e-05 76 3.477e-05 126 Neighborhood of CCNI www.broad.mit.e...
Broad MORF_PSMC1 View Gene Set 1.705e-05 162 5.732e-05 127 Neighborhood of PSMC1 www.broad.mit.e...
Broad GCM_RAD21 View Gene Set 1.993e-05 30 6.65e-05 128 Neighborhood of RAD21 www.broad.mit.e...
Broad GNF2_BUB3 View Gene Set 2.288e-05 22 7.573e-05 129 Neighborhood of BUB3 www.broad.mit.e...
Broad MORF_AP3D1 View Gene Set 2.328e-05 119 7.645e-05 130 Neighborhood of AP3D1 www.broad.mit.e...
Broad GCM_DFFA View Gene Set 2.792e-05 100 9.102e-05 131 Neighborhood of DFFA www.broad.mit.e...
Broad MORF_RAD23B View Gene Set 2.988e-05 159 9.664e-05 132 Neighborhood of RAD23B www.broad.mit.e...
Broad MORF_EIF4A2 View Gene Set 3.083e-05 120 9.897e-05 133 Neighborhood of EIF4A2 www.broad.mit.e...
Broad GNF2_EIF3S6 View Gene Set 3.35e-05 109 0.0001067 134 Neighborhood of EIF3S6 www.broad.mit.e...
Broad GCM_SMARCC1 View Gene Set 3.608e-05 33 0.0001141 135 Neighborhood of SMARCC1 www.broad.mit.e...
Broad MORF_PRDX3 View Gene Set 4.271e-05 79 0.0001341 136 Neighborhood of PRDX3 www.broad.mit.e...
Broad GCM_TPR View Gene Set 8.912e-05 29 0.0002778 137 Neighborhood of TPR www.broad.mit.e...
Broad MORF_NME2 View Gene Set 9.725e-05 145 0.0003009 138 Neighborhood of NME2 www.broad.mit.e...
Broad GNF2_ST13 View Gene Set 0.0001144 56 0.0003515 139 Neighborhood of ST13 www.broad.mit.e...
Broad MORF_TERF2IP View Gene Set 0.0001204 99 0.0003674 140 Neighborhood of TERF2IP www.broad.mit.e...
Broad MORF_SNRP70 View Gene Set 0.0001859 50 0.0005629 141 Neighborhood of SNRP70 www.broad.mit.e...
Broad MORF_REV3L View Gene Set 0.0002027 52 0.0006095 142 Neighborhood of REV3L www.broad.mit.e...
Broad GCM_BECN1 View Gene Set 0.000499 59 0.00149 143 Neighborhood of BECN1 www.broad.mit.e...
Broad MORF_AP2M1 View Gene Set 0.0005152 197 0.001528 144 Neighborhood of AP2M1 www.broad.mit.e...
Broad MORF_RFC1 View Gene Set 0.0006335 98 0.001866 145 Neighborhood of RFC1 www.broad.mit.e...
Broad GCM_PFN1 View Gene Set 0.001141 47 0.003336 146 Neighborhood of PFN1 www.broad.mit.e...
Broad GCM_RING1 View Gene Set 0.001348 106 0.003915 147 Neighborhood of RING1 www.broad.mit.e...
Broad MORF_BMI1 View Gene Set 0.002374 71 0.00685 148 Neighborhood of BMI1 www.broad.mit.e...
Broad GCM_PPM1D View Gene Set 0.002577 22 0.007385 149 Neighborhood of PPM1D www.broad.mit.e...
Broad GCM_SUPT4H1 View Gene Set 0.003579 58 0.01019 150 Neighborhood of SUPT4H1 www.broad.mit.e...
Broad GCM_AIP View Gene Set 0.003805 36 0.01076 151 Neighborhood of AIP www.broad.mit.e...
Broad MORF_RAP1A View Gene Set 0.003878 122 0.01089 152 Neighborhood of RAP1A www.broad.mit.e...
Broad MORF_SS18 View Gene Set 0.004736 55 0.01322 153 Neighborhood of SS18 www.broad.mit.e...
Broad MORF_TPR View Gene Set 0.005038 131 0.01397 154 Neighborhood of TPR www.broad.mit.e...
Broad GCM_HBP1 View Gene Set 0.005589 54 0.0154 155 Neighborhood of HBP1 www.broad.mit.e...
Broad MORF_PPP2R5E View Gene Set 0.00641 76 0.01754 156 Neighborhood of PPP2R5E www.broad.mit.e...
Broad MORF_ACTG1 View Gene Set 0.006489 134 0.01765 157 Neighborhood of ACTG1 www.broad.mit.e...
Broad GCM_FANCC View Gene Set 0.006591 120 0.01781 158 Neighborhood of FANCC www.broad.mit.e...
Broad GCM_HDAC1 View Gene Set 0.006784 30 0.01822 159 Neighborhood of HDAC1 www.broad.mit.e...
Broad MORF_FANCG View Gene Set 0.007011 148 0.01871 160 Neighborhood of FANCG www.broad.mit.e...
Broad GCM_DENR View Gene Set 0.00808 40 0.02143 161 Neighborhood of DENR www.broad.mit.e...
Broad MORF_SP3 View Gene Set 0.008227 69 0.02169 162 Neighborhood of SP3 www.broad.mit.e...
Broad GCM_CASP2 View Gene Set 0.008619 21 0.02258 163 Neighborhood of CASP2 www.broad.mit.e...
Broad MORF_HEAB View Gene Set 0.00893 71 0.02325 164 Neighborhood of HEAB www.broad.mit.e...
Broad MORF_RFC5 View Gene Set 0.01033 69 0.02674 165 Neighborhood of RFC5 www.broad.mit.e...
Broad GCM_CSNK1A1 View Gene Set 0.01119 28 0.02879 166 Neighborhood of CSNK1A1 www.broad.mit.e...
Broad GNF2_CDC27 View Gene Set 0.01163 56 0.02974 167 Neighborhood of CDC27 www.broad.mit.e...
Broad MORF_RAC1 View Gene Set 0.01194 196 0.03035 168 Neighborhood of RAC1 www.broad.mit.e...
Broad GCM_SMARCD1 View Gene Set 0.01264 101 0.03194 169 Neighborhood of SMARCD1 www.broad.mit.e...
Broad GCM_DPF2 View Gene Set 0.01482 32 0.03722 170 Neighborhood of DPF2 www.broad.mit.e...
Broad MORF_BAG5 View Gene Set 0.01548 48 0.03865 171 Neighborhood of BAG5 www.broad.mit.e...
Broad GCM_MLL View Gene Set 0.01586 130 0.03938 172 Neighborhood of MLL www.broad.mit.e...
Broad MORF_PAPSS1 View Gene Set 0.01611 98 0.03975 173 Neighborhood of PAPSS1 www.broad.mit.e...
Broad MORF_PSMC2 View Gene Set 0.01883 100 0.04621 174 Neighborhood of PSMC2 www.broad.mit.e...
Broad MORF_FDXR View Gene Set 0.01978 205 0.04826 175 Neighborhood of FDXR www.broad.mit.e...

Gene Set Collection: Broad.c4.CM

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad module_17 View Gene Set 3.53e-16 351 1.603e-13 1 Genes in module_17 www.broad.mit.e...
Broad module_244 View Gene Set 2.707e-14 182 6.146e-12 2 Genes in module_244 www.broad.mit.e...
Broad module_32 View Gene Set 1.095e-13 227 1.286e-11 3 Genes in module_32 www.broad.mit.e...
Broad module_198 View Gene Set 1.133e-13 288 1.286e-11 3 Genes in module_198 www.broad.mit.e...
Broad module_54 View Gene Set 2.623e-13 242 2.382e-11 5 Genes in module_54 www.broad.mit.e...
Broad module_183 View Gene Set 5.41e-13 52 4.094e-11 6 Genes in module_183 www.broad.mit.e...
Broad module_98 View Gene Set 6.606e-13 375 4.285e-11 7 Genes in module_98 www.broad.mit.e...
Broad module_252 View Gene Set 7.455e-12 224 4.23e-10 8 Genes in module_252 www.broad.mit.e...
Broad module_158 View Gene Set 4.134e-09 41 2.085e-07 9 Genes in module_158 www.broad.mit.e...
Broad module_125 View Gene Set 1.293e-08 42 5.871e-07 10 Genes in module_125 www.broad.mit.e...
Broad module_35 View Gene Set 2.231e-08 16 9.208e-07 11 Genes in module_35 www.broad.mit.e...
Broad module_110 View Gene Set 8.34e-08 15 3.155e-06 12 Genes in module_110 www.broad.mit.e...
Broad module_219 View Gene Set 1.022e-07 26 3.568e-06 13 Genes in module_219 www.broad.mit.e...
Broad module_124 View Gene Set 1.824e-07 92 5.914e-06 14 Genes in module_124 www.broad.mit.e...
Broad module_133 View Gene Set 3.287e-07 15 9.949e-06 15 Genes in module_133 www.broad.mit.e...
Broad module_160 View Gene Set 4.416e-07 15 1.253e-05 16 Genes in module_160 www.broad.mit.e...
Broad module_57 View Gene Set 7.248e-07 54 1.936e-05 17 Genes in module_57 www.broad.mit.e...
Broad module_61 View Gene Set 1.019e-06 50 2.569e-05 18 Genes in module_61 www.broad.mit.e...
Broad module_337 View Gene Set 1.242e-06 59 2.967e-05 19 Genes in module_337 www.broad.mit.e...
Broad module_397 View Gene Set 3.596e-06 114 8.162e-05 20 Genes in module_397 www.broad.mit.e...
Broad module_8 View Gene Set 3.994e-06 403 8.636e-05 21 Genes in module_8 www.broad.mit.e...
Broad module_392 View Gene Set 1.176e-05 18 0.0002426 22 Genes in module_392 www.broad.mit.e...
Broad module_278 View Gene Set 1.826e-05 34 0.0003605 23 Genes in module_278 www.broad.mit.e...
Broad module_91 View Gene Set 2.078e-05 37 0.0003931 24 Genes in module_91 www.broad.mit.e...
Broad module_28 View Gene Set 2.304e-05 32 0.0004023 25 Genes in module_28 www.broad.mit.e...
Broad module_83 View Gene Set 2.271e-05 296 0.0004023 25 Genes in module_83 www.broad.mit.e...
Broad module_102 View Gene Set 3.5e-05 18 0.0005885 27 Genes in module_102 www.broad.mit.e...
Broad module_197 View Gene Set 3.837e-05 170 0.0006221 28 Genes in module_197 www.broad.mit.e...
Broad module_16 View Gene Set 5.613e-05 495 0.0008495 29 Genes in module_16 www.broad.mit.e...
Broad module_320 View Gene Set 5.493e-05 19 0.0008495 29 Genes in module_320 www.broad.mit.e...
Broad module_388 View Gene Set 9.571e-05 17 0.001402 31 Genes in module_388 www.broad.mit.e...
Broad module_403 View Gene Set 0.0001002 44 0.001422 32 Genes in module_403 www.broad.mit.e...
Broad module_53 View Gene Set 0.0001524 389 0.002097 33 Genes in module_53 www.broad.mit.e...
Broad module_457 View Gene Set 0.0002229 9 0.002976 34 Genes in module_457 www.broad.mit.e...
Broad module_3 View Gene Set 0.0002673 374 0.003467 35 Genes in module_3 www.broad.mit.e...
Broad module_273 View Gene Set 0.0003304 50 0.004167 36 Genes in module_273 www.broad.mit.e...
Broad module_538 View Gene Set 0.0004454 8 0.005465 37 Genes in module_538 www.broad.mit.e...
Broad module_126 View Gene Set 0.0005122 173 0.006119 38 Genes in module_126 www.broad.mit.e...
Broad module_21 View Gene Set 0.0005314 10 0.006186 39 Genes in module_21 www.broad.mit.e...
Broad module_50 View Gene Set 0.0005777 13 0.006549 40 Genes in module_50 www.broad.mit.e...
Broad module_352 View Gene Set 0.0005914 17 0.006549 40 Genes in module_352 www.broad.mit.e...
Broad module_306 View Gene Set 0.0008316 26 0.008989 42 Genes in module_306 www.broad.mit.e...
Broad module_42 View Gene Set 0.001142 25 0.01205 43 Genes in module_42 www.broad.mit.e...
Broad module_77 View Gene Set 0.001236 28 0.01247 44 Genes in module_77 www.broad.mit.e...
Broad module_149 View Gene Set 0.001232 36 0.01247 44 Genes in module_149 www.broad.mit.e...
Broad module_376 View Gene Set 0.001288 7 0.01272 46 Genes in module_376 www.broad.mit.e...
Broad module_450 View Gene Set 0.002085 9 0.02014 47 Genes in module_450 www.broad.mit.e...
Broad module_18 View Gene Set 0.002483 434 0.02349 48 Genes in module_18 www.broad.mit.e...
Broad module_115 View Gene Set 0.002729 27 0.02529 49 Genes in module_115 www.broad.mit.e...
Broad module_152 View Gene Set 0.002997 121 0.02721 50 Genes in module_152 www.broad.mit.e...
Broad module_31 View Gene Set 0.003568 7 0.03176 51 Genes in module_31 www.broad.mit.e...

Gene Set Collection: Broad.c5.BP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 1.807e-31 1197 1.49e-28 1 Genes annotated by the GO term GO:0006139. The chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad RNA_METABOLIC_PROCESS View Gene Set 9.347e-24 801 3.4e-21 2 Genes annotated by the GO term GO:0016070. The chemical reactions and pathways involving RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. www.broad.mit.e...
Broad RNA_PROCESSING View Gene Set 1.237e-23 147 3.4e-21 2 Genes annotated by the GO term GO:0006396. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. www.broad.mit.e...
Broad BIOPOLYMER_METABOLIC_PROCESS View Gene Set 4.857e-19 1623 1.002e-16 4 Genes annotated by the GO term GO:0043283. The chemical reactions and pathways involving biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. www.broad.mit.e...
Broad RNA_SPLICING View Gene Set 2.472e-13 73 4.08e-11 5 Genes annotated by the GO term GO:0008380. The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. www.broad.mit.e...
Broad DNA_METABOLIC_PROCESS View Gene Set 1.361e-11 253 1.871e-09 6 Genes annotated by the GO term GO:0006259. The chemical reactions and pathways involving DNA deoxyribonucleic acid one of the two main types of nucleic acid consisting of a long unbranched macromolecule formed from one or more commonly two strands of linked deoxyribonucleotides. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY View Gene Set 1.019e-10 74 1.201e-08 7 Genes annotated by the GO term GO:0022613. The cellular process by which a complex containing RNA and proteins is synthesized aggregates and bonds together. www.broad.mit.e...
Broad MRNA_METABOLIC_PROCESS View Gene Set 4.7e-10 70 4.847e-08 8 Genes annotated by the GO term GO:0016071. The chemical reactions and pathways involving mRNA messenger RNA which is responsible for carrying the coded genetic 'message' transcribed from DNA to sites of protein assembly at the ribosomes. www.broad.mit.e...
Broad MRNA_PROCESSING_GO_0006397 View Gene Set 6.255e-10 59 5.734e-08 9 Genes annotated by the GO term GO:0006397. Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. www.broad.mit.e...
Broad TRANSCRIPTION View Gene Set 4.431e-09 738 3.655e-07 10 Genes annotated by the GO term GO:0006350. The synthesis of either RNA on a template of DNA or DNA on a template of RNA. www.broad.mit.e...
Broad TRANSCRIPTION_DNA_DEPENDENT View Gene Set 1.883e-08 623 1.295e-06 11 Genes annotated by the GO term GO:0006351. The synthesis of RNA on a template of DNA. www.broad.mit.e...
Broad RNA_BIOSYNTHETIC_PROCESS View Gene Set 1.863e-08 625 1.295e-06 11 Genes annotated by the GO term GO:0032774. The chemical reactions and pathways resulting in the formation of RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. www.broad.mit.e...
Broad DNA_REPLICATION View Gene Set 2.249e-08 101 1.427e-06 13 Genes annotated by the GO term GO:0006260. The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. www.broad.mit.e...
Broad CHROMOSOME_ORGANIZATION_AND_BIOGENESIS View Gene Set 2.764e-07 117 1.629e-05 14 Genes annotated by the GO term GO:0051276. A process that is carried out at the cellular level that results in the formation arrangement of constituent parts or disassembly of chromosomes structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. www.broad.mit.e...
Broad M_PHASE View Gene Set 3.381e-07 111 1.86e-05 15 Genes annotated by the GO term GO:0000279. Progression through M phase the part of the cell cycle comprising nuclear division. www.broad.mit.e...
Broad CELLULAR_BIOSYNTHETIC_PROCESS View Gene Set 5.134e-07 311 2.551e-05 16 Genes annotated by the GO term GO:0044249. The chemical reactions and pathways resulting in the formation of substances carried out by individual cells. www.broad.mit.e...
Broad REGULATION_OF_GENE_EXPRESSION View Gene Set 5.411e-07 660 2.551e-05 16 Genes annotated by the GO term GO:0010468. Any process that modulates the frequency rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. www.broad.mit.e...
Broad RNA_SPLICINGVIA_TRANSESTERIFICATION_REACTIONS View Gene Set 5.829e-07 27 2.551e-05 16 Genes annotated by the GO term GO:0000375. Splicing of RNA via a series of two transesterification reactions. www.broad.mit.e...
Broad TRANSLATION View Gene Set 5.875e-07 177 2.551e-05 16 Genes annotated by the GO term GO:0006412. The chemical reactions and pathways resulting in the formation of a protein. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. www.broad.mit.e...
Broad PROTEIN_RNA_COMPLEX_ASSEMBLY View Gene Set 8.783e-07 59 3.623e-05 20 Genes annotated by the GO term GO:0022618. The aggregation arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. www.broad.mit.e...
Broad TRNA_METABOLIC_PROCESS View Gene Set 1.084e-06 18 4.257e-05 21 Genes annotated by the GO term GO:0006399. The chemical reactions and pathways involving tRNA transfer RNA a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases the function of which has not been completely established. www.broad.mit.e...
Broad RESPONSE_TO_DNA_DAMAGE_STIMULUS View Gene Set 1.277e-06 159 4.79e-05 22 Genes annotated by the GO term GO:0006974. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. www.broad.mit.e...
Broad DNA_REPAIR View Gene Set 1.415e-06 123 4.869e-05 23 Genes annotated by the GO term GO:0006281. The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations chemical mutagens fungal and bacterial toxins etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal base excision repair nucleotide excision repair photoreactivation bypass double-strand break repair pathway and mismatch repair pathway. www.broad.mit.e...
Broad CELL_CYCLE_PROCESS View Gene Set 1.416e-06 187 4.869e-05 23 Genes annotated by the GO term GO:0022402. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. www.broad.mit.e...
Broad COENZYME_METABOLIC_PROCESS View Gene Set 1.74e-06 37 5.741e-05 25 Genes annotated by the GO term GO:0006732. The chemical reactions and pathways involving coenzymes any of various nonprotein organic cofactors that are required in addition to an enzyme and a substrate for an enzymatic reaction to proceed. www.broad.mit.e...
Broad CELL_CYCLE_PHASE View Gene Set 2.41e-06 167 7.468e-05 26 Genes annotated by the GO term GO:0022403. A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. www.broad.mit.e...
Broad REGULATION_OF_GENE_EXPRESSION_EPIGENETIC View Gene Set 2.444e-06 30 7.468e-05 26 Genes annotated by the GO term GO:0040029. Any process that modulates the frequency rate or extent of gene expression; the process is mitotically or meiotically heritable or is stably self-propagated in the cytoplasm of a resting cell and does not entail a change in DNA sequence. www.broad.mit.e...
Broad CELL_CYCLE_GO_0007049 View Gene Set 2.806e-06 304 8.267e-05 28 Genes annotated by the GO term GO:0007049. The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. www.broad.mit.e...
Broad COFACTOR_METABOLIC_PROCESS View Gene Set 3.489e-06 53 9.927e-05 29 Genes annotated by the GO term GO:0051186. The chemical reactions and pathways involving a cofactor a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic such as the metal atoms zinc iron and copper in certain forms or organic in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. www.broad.mit.e...
Broad TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 3.72e-06 449 0.0001023 30 Genes annotated by the GO term GO:0006366. The synthesis of RNA from a DNA template by RNA polymerase II (Pol II) originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). www.broad.mit.e...
Broad RESPONSE_TO_ENDOGENOUS_STIMULUS View Gene Set 5.403e-06 197 0.0001438 31 Genes annotated by the GO term GO:0009719. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of an endogenous stimulus. www.broad.mit.e...
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_TRANSPORT View Gene Set 6.198e-06 31 0.0001598 32 Genes annotated by the GO term GO:0015931. The directed movement of nucleobases nucleosides nucleotides and nucleic acids into out of within or between cells. www.broad.mit.e...
Broad ONE_CARBON_COMPOUND_METABOLIC_PROCESS View Gene Set 7.86e-06 26 0.0001965 33 Genes annotated by the GO term GO:0006730. The chemical reactions and pathways involving compounds containing a single carbon atom. www.broad.mit.e...
Broad M_PHASE_OF_MITOTIC_CELL_CYCLE View Gene Set 1.542e-05 83 0.0003741 34 Genes annotated by the GO term GO:0000087. Progression through M phase the part of the mitotic cell cycle during which mitosis takes place. www.broad.mit.e...
Broad RIBOSOME_BIOGENESIS_AND_ASSEMBLY View Gene Set 1.739e-05 14 0.00041 35 Genes annotated by the GO term GO:0042254. The process of the formation of the constituents of the ribosome subunits their assembly and their transport to the sites of protein synthesis. www.broad.mit.e...
Broad RNA_EXPORT_FROM_NUCLEUS View Gene Set 1.889e-05 20 0.0004329 36 Genes annotated by the GO term GO:0006405. The directed movement of RNA from the nucleus to the cytoplasm. www.broad.mit.e...
Broad MITOSIS View Gene Set 2.764e-05 81 0.0006163 37 Genes annotated by the GO term GO:0007067. Progression through mitosis the division of the eukaryotic cell nucleus to produce two daughter nuclei that usually contain the identical chromosome complement to their mother. www.broad.mit.e...
Broad AMINO_ACID_METABOLIC_PROCESS View Gene Set 3.844e-05 75 0.0008346 38 Genes annotated by the GO term GO:0006520. The chemical reactions and pathways involving amino acids organic acids containing one or more amino substituents. www.broad.mit.e...
Broad MITOTIC_CELL_CYCLE View Gene Set 4.488e-05 148 0.0009255 39 Genes annotated by the GO term GO:0000278. Progression through the phases of the mitotic cell cycle the most common eukaryotic cell cycle which canonically comprises four successive phases called G1 S G2 and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division or G1 and G2 phases may be absent. www.broad.mit.e...
Broad REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS View Gene Set 4.42e-05 601 0.0009255 39 Genes annotated by the GO term GO:0019219. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTION View Gene Set 6.592e-05 555 0.001326 41 Genes annotated by the GO term GO:0045449. Any process that modulates the frequency rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. www.broad.mit.e...
Broad ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CHROMATIN_ARCHITECTURE View Gene Set 9.863e-05 72 0.001937 42 Genes annotated by the GO term GO:0006325. The specification formation and maintenance of the physical structure of eukaryotic chromatin. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT View Gene Set 0.0001259 452 0.002415 43 Genes annotated by the GO term GO:0006355. Any process that modulates the frequency rate or extent of DNA-dependent transcription. www.broad.mit.e...
Broad BASE_EXCISION_REPAIR View Gene Set 0.0001356 16 0.002542 44 Genes annotated by the GO term GO:0006284. In base excision repair an altered base is removed by a DNA glycosylase enzyme followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX_ASSEMBLY View Gene Set 0.0001433 271 0.002626 45 Genes annotated by the GO term GO:0065003. The aggregation arrangement and bonding together of a set of macromolecules to form a complex. www.broad.mit.e...
Broad MITOCHONDRION_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.0001568 47 0.002812 46 Genes annotated by the GO term GO:0007005. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a mitochondrion; includes mitochondrial morphology and distribution and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. www.broad.mit.e...
Broad REGULATION_OF_RNA_METABOLIC_PROCESS View Gene Set 0.0001637 457 0.002874 47 Genes annotated by the GO term GO:0051252. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving RNA. www.broad.mit.e...
Broad REGULATION_OF_CELLULAR_METABOLIC_PROCESS View Gene Set 0.0001765 767 0.003034 48 Genes annotated by the GO term GO:0031323. Any process that modulates the frequency rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. www.broad.mit.e...
Broad CELLULAR_COMPONENT_ASSEMBLY View Gene Set 0.0001923 288 0.003238 49 Genes annotated by the GO term GO:0022607. A cellular process that results in the assembly of a part of the cell. www.broad.mit.e...
Broad DNA_MODIFICATION View Gene Set 0.0002088 10 0.003445 50 Genes annotated by the GO term GO:0006304. The covalent alteration of one or more nucleotide sites in DNA resulting in a change in its properties. www.broad.mit.e...
Broad RRNA_PROCESSING View Gene Set 0.0002736 11 0.004426 51 Genes annotated by the GO term GO:0006364. Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. www.broad.mit.e...
Broad REGULATION_OF_METABOLIC_PROCESS View Gene Set 0.0003123 779 0.004955 52 Genes annotated by the GO term GO:0019222. Any process that modulates the frequency rate or extent of the chemical reactions and pathways within a cell or an organism. www.broad.mit.e...
Broad CHROMATIN_ASSEMBLY_OR_DISASSEMBLY View Gene Set 0.0003429 26 0.005338 53 Genes annotated by the GO term GO:0006333. The formation or destruction of chromatin structures. www.broad.mit.e...
Broad CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY View Gene Set 0.0004244 13 0.006484 54 Genes annotated by the GO term GO:0043624. The disaggregation of a protein complex into its constituent components occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. www.broad.mit.e...
Broad TRNA_PROCESSING View Gene Set 0.0004434 10 0.006651 55 Genes annotated by the GO term GO:0008033. The process by which a pre-tRNA molecule is converted to a mature tRNA ready for addition of an aminoacyl group. www.broad.mit.e...
Broad CATABOLIC_PROCESS View Gene Set 0.0004536 221 0.006682 56 Genes annotated by the GO term GO:0009056. The chemical reactions and pathways resulting in the breakdown of substances including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. www.broad.mit.e...
Broad CELLULAR_CATABOLIC_PROCESS View Gene Set 0.0005401 209 0.007706 57 Genes annotated by the GO term GO:0044248. The chemical reactions and pathways resulting in the breakdown of substances carried out by individual cells. www.broad.mit.e...
Broad RRNA_METABOLIC_PROCESS View Gene Set 0.0005417 12 0.007706 57 Genes annotated by the GO term GO:0016072. The chemical reactions and pathways involving rRNA ribosomal RNA a structural constituent of ribosomes. www.broad.mit.e...
Broad PROTEIN_COMPLEX_DISASSEMBLY View Gene Set 0.0008018 14 0.01121 59 Genes annotated by the GO term GO:0043241. The disaggregation of a protein complex into its constituent components. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. www.broad.mit.e...
Broad BIOPOLYMER_CATABOLIC_PROCESS View Gene Set 0.0008295 115 0.01141 60 Genes annotated by the GO term GO:0043285. The chemical reactions and pathways resulting in the breakdown of biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. www.broad.mit.e...
Broad MACROMOLECULE_CATABOLIC_PROCESS View Gene Set 0.001033 135 0.01374 61 Genes annotated by the GO term GO:0009057. The chemical reactions and pathways resulting in the breakdown of a macromolecule any large molecule including proteins nucleic acids and carbohydrates. www.broad.mit.e...
Broad CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS View Gene Set 0.001027 103 0.01374 61 Genes annotated by the GO term GO:0044265. The chemical reactions and pathways resulting in the breakdown of a macromolecule any large molecule including proteins nucleic acids and carbohydrates as carried out by individual cells. www.broad.mit.e...
Broad MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.001095 34 0.01434 63 Genes annotated by the GO term GO:0000226. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. www.broad.mit.e...
Broad AMINO_ACID_AND_DERIVATIVE_METABOLIC_PROCESS View Gene Set 0.00117 98 0.01508 64 Genes annotated by the GO term GO:0006519. The chemical reactions and pathways involving amino acids organic acids containing one or more amino substituents and compounds derived from amino acids. www.broad.mit.e...
Broad NUCLEAR_EXPORT View Gene Set 0.001194 31 0.01515 65 Genes annotated by the GO term GO:0051168. The directed movement of substances out of the nucleus. www.broad.mit.e...
Broad CHROMATIN_MODIFICATION View Gene Set 0.001273 50 0.01591 66 Genes annotated by the GO term GO:0016568. The alteration of DNA or protein in chromatin which may result in changing the chromatin structure. www.broad.mit.e...
Broad INTRACELLULAR_RECEPTOR_MEDIATED_SIGNALING_PATHWAY View Gene Set 0.001324 21 0.0163 67 Genes annotated by the GO term GO:0030522. Any series of molecular signals initiated by a ligand entering the target cell where it binds to an intracellular receptor. www.broad.mit.e...
Broad TRANSLATIONAL_INITIATION View Gene Set 0.001353 39 0.01641 68 Genes annotated by the GO term GO:0006413. The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome mRNA and an initiation complex that contains the first aminoacyl-tRNA. www.broad.mit.e...
Broad RNA_CATABOLIC_PROCESS View Gene Set 0.001419 22 0.01696 69 Genes annotated by the GO term GO:0006401. The chemical reactions and pathways resulting in the breakdown of RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. www.broad.mit.e...
Broad RESPONSE_TO_ABIOTIC_STIMULUS View Gene Set 0.001504 87 0.01772 70 Genes annotated by the GO term GO:0009628. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of an abiotic (non-living) stimulus. www.broad.mit.e...
Broad DNA_INTEGRITY_CHECKPOINT View Gene Set 0.001582 23 0.01821 71 Genes annotated by the GO term GO:0031570. Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure. www.broad.mit.e...
Broad GLIOGENESIS View Gene Set 0.00159 11 0.01821 71 Genes annotated by the GO term GO:0042063. The process by which glial cells are generated. This includes the production of glial progenitors and their differentiation into mature glia. www.broad.mit.e...
Broad SPLICEOSOME_ASSEMBLY View Gene Set 0.001637 13 0.01851 73 Genes annotated by the GO term GO:0000245. The aggregation arrangement and bonding together of the spliceosome a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX_DISASSEMBLY View Gene Set 0.00171 15 0.01906 74 Genes annotated by the GO term GO:0032984. The disaggregation of a macromolecular complex into its constituent components. www.broad.mit.e...
Broad N_TERMINAL_PROTEIN_AMINO_ACID_MODIFICATION View Gene Set 0.001779 6 0.01928 75 Genes annotated by the GO term GO:0031365. The alteration of the N-terminal amino acid residue in a protein. www.broad.mit.e...
Broad PROTEIN_TARGETING_TO_MITOCHONDRION View Gene Set 0.001813 10 0.01928 75 Genes annotated by the GO term GO:0006626. The process of directing proteins towards and into the mitochondrion mediated by mitochondrial proteins that recognize signals contained within the imported protein. www.broad.mit.e...
Broad STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY View Gene Set 0.001823 20 0.01928 75 Genes annotated by the GO term GO:0030518. Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor. www.broad.mit.e...
Broad NUCLEOCYTOPLASMIC_TRANSPORT View Gene Set 0.001821 83 0.01928 75 Genes annotated by the GO term GO:0006913. The directed movement of molecules between the nucleus and the cytoplasm. www.broad.mit.e...
Broad ORGANELLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.002053 458 0.02144 79 Genes annotated by the GO term GO:0006996. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of any organelle within a cell. www.broad.mit.e...
Broad CELL_CYCLE_CHECKPOINT_GO_0000075 View Gene Set 0.002235 47 0.02304 80 Genes annotated by the GO term GO:0000075. A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. www.broad.mit.e...
Broad BIOSYNTHETIC_PROCESS View Gene Set 0.002335 459 0.02325 81 Genes annotated by the GO term GO:0009058. The energy-requiring part of metabolism in which simpler substances are transformed into more complex ones as in growth and other biosynthetic processes. www.broad.mit.e...
Broad REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER View Gene Set 0.002339 285 0.02325 81 Genes annotated by the GO term GO:0006357. Any process that modulates the frequency rate or extent of transcription from an RNA polymerase II promoter. www.broad.mit.e...
Broad MITOCHONDRIAL_TRANSPORT View Gene Set 0.002284 20 0.02325 81 Genes annotated by the GO term GO:0006839. Transport of substances into out of or within a mitochondrion. www.broad.mit.e...
Broad GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY View Gene Set 0.002469 122 0.02397 84 Genes annotated by the GO term GO:0006091. The chemical reactions and pathways resulting in the formation of precursor metabolites substances from which energy is derived and the processes involved in the liberation of energy from these substances. www.broad.mit.e...
Broad TRANSCRIPTION_FROM_RNA_POLYMERASE_III_PROMOTER View Gene Set 0.002453 19 0.02397 84 Genes annotated by the GO term GO:0006383. The synthesis of RNA from a DNA template by RNA polymerase III (Pol III) originating at a Pol III-specific promoter. www.broad.mit.e...
Broad MEIOTIC_CELL_CYCLE View Gene Set 0.002529 34 0.02426 86 Genes annotated by the GO term GO:0051321. Progression through the phases of the meiotic cell cycle in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell. www.broad.mit.e...
Broad CELLULAR_RESPIRATION View Gene Set 0.00277 19 0.02627 87 Genes annotated by the GO term GO:0045333. The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration). www.broad.mit.e...
Broad NUCLEAR_TRANSPORT View Gene Set 0.002932 84 0.02749 88 Genes annotated by the GO term GO:0051169. The directed movement of substances into out of or within the nucleus. www.broad.mit.e...
Broad ELECTRON_TRANSPORT_GO_0006118 View Gene Set 0.003177 51 0.02945 89 Genes annotated by the GO term GO:0006118. The transport of electrons from an electron donor to an electron acceptor. www.broad.mit.e...
Broad RESPONSE_TO_HEAT View Gene Set 0.003326 10 0.03049 90 Genes annotated by the GO term GO:0009408. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a heat stimulus a temperature stimulus above the optimal temperature for that organism. www.broad.mit.e...
Broad DNA_DEPENDENT_DNA_REPLICATION View Gene Set 0.003539 55 0.03209 91 Genes annotated by the GO term GO:0006261. The process whereby new strands of DNA are synthesized using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. www.broad.mit.e...
Broad MEIOSIS_I View Gene Set 0.004423 19 0.03924 92 Genes annotated by the GO term GO:0007127. Progression through the first phase of meiosis in which cells divide and homologous chromosomes are paired and segregated from each other producing two daughter cells. www.broad.mit.e...
Broad MITOTIC_SPINDLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.004393 9 0.03924 92 Genes annotated by the GO term GO:0007052. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the microtubule spindle during a mitotic cell cycle. www.broad.mit.e...
Broad AEROBIC_RESPIRATION View Gene Set 0.004539 15 0.03984 94 Genes annotated by the GO term GO:0009060. The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor. www.broad.mit.e...
Broad COENZYME_BIOSYNTHETIC_PROCESS View Gene Set 0.005468 10 0.04749 95 Genes annotated by the GO term GO:0009108. The chemical reactions and pathways resulting in the formation of coenzymes any of various nonprotein organic cofactors that are required in addition to an enzyme and a substrate for an enzymatic reaction to proceed. www.broad.mit.e...
Broad SPINDLE_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.005711 10 0.04908 96 Genes annotated by the GO term GO:0007051. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the spindle the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. www.broad.mit.e...

Gene Set Collection: Broad.c5.CC

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad NUCLEAR_PART View Gene Set 5.436e-34 543 6.333e-32 1 Genes annotated by the GO term GO:0044428. Any constituent part of the nucleus a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. www.broad.mit.e...
Broad NUCLEUS View Gene Set 2.785e-34 1353 6.333e-32 1 Genes annotated by the GO term GO:0005634. A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells the nucleus contains all of the cell's chromosomes except the organellar chromosomes and is the site of RNA synthesis and processing. In some species or in specialized cell types RNA metabolism or DNA replication may be absent. www.broad.mit.e...
Broad ORGANELLE_LUMEN View Gene Set 7.29e-24 434 4.247e-22 3 Genes annotated by the GO term GO:0043233. The volume enclosed by the membranes of a particular organelle e.g. endoplasmic reticulum lumen or the space between the two lipid bilayers of a double membrane surrounding an organelle e.g. nuclear membrane lumen. www.broad.mit.e...
Broad MEMBRANE_ENCLOSED_LUMEN View Gene Set 7.29e-24 434 4.247e-22 3 Genes annotated by the GO term GO:0031974. The enclosed volume within a sealed membrane or between two sealed membranes. www.broad.mit.e...
Broad MITOCHONDRION View Gene Set 1.663e-23 335 7.748e-22 5 Genes annotated by the GO term GO:0005739. A semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. www.broad.mit.e...
Broad INTRACELLULAR_ORGANELLE_PART View Gene Set 1.288e-20 1144 5.002e-19 6 Genes annotated by the GO term GO:0044446. A constituent part of an intracellular organelle an organized structure of distinctive morphology and function occurring within the cell. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad ORGANELLE_PART View Gene Set 2.47e-20 1149 8.222e-19 7 Genes annotated by the GO term GO:0044422. Any constituent part of an organelle an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. www.broad.mit.e...
Broad NUCLEAR_LUMEN View Gene Set 4.496e-20 365 1.31e-18 8 Genes annotated by the GO term GO:0031981. The volume enclosed by the nuclear inner membrane. www.broad.mit.e...
Broad RIBONUCLEOPROTEIN_COMPLEX View Gene Set 1.424e-18 129 3.687e-17 9 Genes annotated by the GO term GO:0030529. A macromolecular complex containing both protein and RNA molecules. www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX View Gene Set 3.976e-18 914 9.264e-17 10 Genes annotated by the GO term GO:0032991. A stable assembly of two or more macromolecules i.e. proteins nucleic acids carbohydrates or lipids in which the constituent parts function together. www.broad.mit.e...
Broad MITOCHONDRIAL_PART View Gene Set 4.935e-16 140 1.045e-14 11 Genes annotated by the GO term GO:0044429. Any constituent part of a mitochondrion a semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. www.broad.mit.e...
Broad ENVELOPE View Gene Set 1.423e-13 165 2.551e-12 12 Genes annotated by the GO term GO:0031975. A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers and may include a cell wall layer also includes the space between layers. www.broad.mit.e...
Broad ORGANELLE_ENVELOPE View Gene Set 1.423e-13 165 2.551e-12 12 Genes annotated by the GO term GO:0031967. A double membrane structure enclosing an organelle including two lipid bilayers and the region between them. In some cases an organelle envelope may have more than two membranes. www.broad.mit.e...
Broad NUCLEOPLASM View Gene Set 1.474e-12 266 2.453e-11 14 Genes annotated by the GO term GO:0005654. That part of the nuclear content other than the chromosomes or the nucleolus. www.broad.mit.e...
Broad NUCLEOLUS View Gene Set 7.718e-11 116 1.199e-09 15 Genes annotated by the GO term GO:0005730. A small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA the processing of this RNA into 5.8S 18S and 28S components of ribosomal RNA and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. www.broad.mit.e...
Broad MITOCHONDRIAL_MEMBRANE View Gene Set 2.564e-10 85 3.735e-09 16 Genes annotated by the GO term GO:0031966. Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. www.broad.mit.e...
Broad PROTEIN_COMPLEX View Gene Set 4.12e-10 799 5.647e-09 17 Genes annotated by the GO term GO:0043234. Any protein group composed of two or more subunits which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. www.broad.mit.e...
Broad MITOCHONDRIAL_ENVELOPE View Gene Set 9.142e-10 95 1.183e-08 18 Genes annotated by the GO term GO:0005740. The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space. www.broad.mit.e...
Broad NUCLEOPLASM_PART View Gene Set 1.699e-09 202 2.084e-08 19 Genes annotated by the GO term GO:0044451. Any constituent part of the nucleoplasm that part of the nuclear content other than the chromosomes or the nucleolus. www.broad.mit.e...
Broad ORGANELLE_INNER_MEMBRANE View Gene Set 6.611e-09 74 7.701e-08 20 Genes annotated by the GO term GO:0019866. The inner i.e. lumen-facing lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites. www.broad.mit.e...
Broad MITOCHONDRIAL_INNER_MEMBRANE View Gene Set 9.177e-09 66 1.018e-07 21 Genes annotated by the GO term GO:0005743. The inner i.e. lumen-facing lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. www.broad.mit.e...
Broad MITOCHONDRIAL_MATRIX View Gene Set 1.523e-08 46 1.543e-07 22 Genes annotated by the GO term GO:0005759. The gel-like material with considerable fine structure that lies in the matrix space or lumen of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and in some organisms the enzymes concerned with fatty-acid oxidation. www.broad.mit.e...
Broad MITOCHONDRIAL_LUMEN View Gene Set 1.523e-08 46 1.543e-07 22 Genes annotated by the GO term GO:0031980. The volume enclosed by the mitochondrial inner membrane. www.broad.mit.e...
Broad SPLICEOSOME View Gene Set 4.757e-08 44 4.618e-07 24 Genes annotated by the GO term GO:0005681. A ribonucleoprotein complex containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron. www.broad.mit.e...
Broad CHROMOSOME View Gene Set 1.072e-07 122 9.99e-07 25 Genes annotated by the GO term GO:0005694. A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. www.broad.mit.e...
Broad SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX View Gene Set 3.7e-07 20 3.316e-06 26 Genes annotated by the GO term GO:0030532. A complex composed of RNA of the small nuclear RNA (snRNA) class and protein found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain e.g. U1 snRNP or U4/U6 snRNP. Many but not all of these complexes are involved in splicing of nuclear mRNAs. www.broad.mit.e...
Broad CHROMOSOMAL_PART View Gene Set 9.836e-07 95 8.488e-06 27 Genes annotated by the GO term GO:0044427. Any constituent part of a chromosome a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. www.broad.mit.e...
Broad PORE_COMPLEX View Gene Set 1.118e-06 34 9.305e-06 28 Genes annotated by the GO term GO:0046930. Any small opening in a membrane that allows the passage of gases and/or liquids. www.broad.mit.e...
Broad MITOCHONDRIAL_MEMBRANE_PART View Gene Set 1.208e-06 52 9.705e-06 29 Genes annotated by the GO term GO:0044455. Any constituent part of the mitochondrial membrane either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. www.broad.mit.e...
Broad NUCLEAR_PORE View Gene Set 1.275e-06 29 9.901e-06 30 Genes annotated by the GO term GO:0005643. Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell where the inner and outer nuclear membranes are joined. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE View Gene Set 1.673e-06 48 1.257e-05 31 Genes annotated by the GO term GO:0031965. Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. www.broad.mit.e...
Broad ORGANELLAR_RIBOSOME View Gene Set 1.823e-06 22 1.287e-05 32 Genes annotated by the GO term GO:0000313. A ribosome contained within a subcellular organelle. www.broad.mit.e...
Broad MITOCHONDRIAL_RIBOSOME View Gene Set 1.823e-06 22 1.287e-05 32 Genes annotated by the GO term GO:0005761. A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. www.broad.mit.e...
Broad NUCLEAR_MEMBRANE_PART View Gene Set 2.409e-06 40 1.651e-05 34 Genes annotated by the GO term GO:0044453. Any constituent part of the nuclear membrane the envelope that surrounds the nucleus of eukaryotic cells. www.broad.mit.e...
Broad RIBOSOMAL_SUBUNIT View Gene Set 9.359e-06 20 6.231e-05 35 Genes annotated by the GO term GO:0033279. Either of the two ribonucleoprotein complexes that associate to form a ribosome. www.broad.mit.e...
Broad NUCLEAR_ENVELOPE View Gene Set 1.474e-05 71 9.538e-05 36 Genes annotated by the GO term GO:0005635. The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space a gap of width 20-40 nm (also called the perinuclear space). www.broad.mit.e...
Broad CHROMATIN View Gene Set 2.482e-05 35 0.0001563 37 Genes annotated by the GO term GO:0000785. The ordered and organized complex of DNA and protein that forms the chromosome. www.broad.mit.e...
Broad RIBOSOME View Gene Set 2.88e-05 39 0.0001766 38 Genes annotated by the GO term GO:0005840. An intracellular organelle about 200 A in diameter consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits one large and one small each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients expressed in Svedberg units (symbol: S). Hence the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes eukaryotes mitochondria and chloroplasts have characteristically distinct ribosomal proteins. www.broad.mit.e...
Broad NUCLEOLAR_PART View Gene Set 3.746e-05 16 0.0002238 39 Genes annotated by the GO term GO:0044452. Any constituent part of a nucleolus a small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. www.broad.mit.e...
Broad HETEROGENEOUS_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX View Gene Set 6.075e-05 9 0.0003539 40 Genes annotated by the GO term GO:0030530. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II that which is translated into protein) with protein which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA. www.broad.mit.e...
Broad DNA_DIRECTED_RNA_POLYMERASEII_HOLOENZYME View Gene Set 9.753e-05 65 0.0005543 41 Genes annotated by the GO term GO:0016591. Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA D E F and H which are required for promoter recognition and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA. www.broad.mit.e...
Broad NUCLEAR_CHROMOSOME View Gene Set 0.0001347 53 0.000747 42 Genes annotated by the GO term GO:0000228. A chromosome found in the nucleus of a eukaryotic cell. www.broad.mit.e...
Broad NON_MEMBRANE_BOUND_ORGANELLE View Gene Set 0.0003695 613 0.001913 43 Genes annotated by the GO term GO:0043228. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane. Includes ribosomes the cytoskeleton and chromosomes. www.broad.mit.e...
Broad INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE View Gene Set 0.0003695 613 0.001913 43 Genes annotated by the GO term GO:0043232. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes the cytoskeleton and chromosomes. www.broad.mit.e...
Broad CONDENSED_CHROMOSOME View Gene Set 0.0003678 32 0.001913 43 Genes annotated by the GO term GO:0000793. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. www.broad.mit.e...
Broad PROTEASOME_COMPLEX View Gene Set 0.000388 23 0.001965 46 Genes annotated by the GO term GO:0000502. A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. www.broad.mit.e...
Broad ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.0005787 11 0.002752 47 Genes annotated by the GO term GO:0000314. The smaller of the two subunits of an organellar ribosome. www.broad.mit.e...
Broad MITOCHONDRIAL_SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.0005787 11 0.002752 47 Genes annotated by the GO term GO:0005763. The smaller of the two subunits of a mitochondrial ribosome. www.broad.mit.e...
Broad SMALL_RIBOSOMAL_SUBUNIT View Gene Set 0.0005787 11 0.002752 47 Genes annotated by the GO term GO:0015935. The smaller of the two subunits of a ribosome. www.broad.mit.e...
Broad MITOCHONDRIAL_OUTER_MEMBRANE View Gene Set 0.0008002 18 0.003729 50 Genes annotated by the GO term GO:0005741. The outer i.e. cytoplasm-facing lipid bilayer of the mitochondrial envelope. www.broad.mit.e...
Broad DNA_DIRECTED_RNA_POLYMERASE_COMPLEX View Gene Set 0.001172 16 0.004966 51 Genes annotated by the GO term GO:0000428. A protein complex that possesses DNA-directed RNA polymerase activity. www.broad.mit.e...
Broad CONDENSED_NUCLEAR_CHROMOSOME View Gene Set 0.00116 17 0.004966 51 Genes annotated by the GO term GO:0000794. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure that remains in the nucleus. www.broad.mit.e...
Broad MICROTUBULE_ORGANIZING_CENTER View Gene Set 0.001131 64 0.004966 51 Genes annotated by the GO term GO:0005815. A region in a eukaryotic cell such as a centrosome or basal body from which microtubules grow. www.broad.mit.e...
Broad RNA_POLYMERASE_COMPLEX View Gene Set 0.001172 16 0.004966 51 Genes annotated by the GO term GO:0030880. Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits. www.broad.mit.e...
Broad NUCLEAR_DNA_DIRECTED_RNA_POLYMERASE_COMPLEX View Gene Set 0.001172 16 0.004966 51 Genes annotated by the GO term GO:0055029. A protein complex located in the nucleus that possesses DNA-directed RNA polymerase activity. www.broad.mit.e...
Broad NUCLEAR_BODY View Gene Set 0.001222 31 0.005086 56 Genes annotated by the GO term GO:0016604. Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. www.broad.mit.e...
Broad NUCLEAR_CHROMOSOME_PART View Gene Set 0.001279 33 0.005229 57 Genes annotated by the GO term GO:0044454. Any constituent part of a nuclear chromosome a chromosome found in the nucleus of a eukaryotic cell. www.broad.mit.e...
Broad ORGANELLE_OUTER_MEMBRANE View Gene Set 0.001303 24 0.005235 58 Genes annotated by the GO term GO:0031968. The outer i.e. cytoplasm-facing lipid bilayer of an organelle envelope. www.broad.mit.e...
Broad INTEGRATOR_COMPLEX View Gene Set 0.001647 13 0.006506 59 Genes annotated by the GO term GO:0032039. A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II. www.broad.mit.e...
Broad TRANSCRIPTION_FACTOR_COMPLEX View Gene Set 0.001933 84 0.007508 60 Genes annotated by the GO term GO:0005667. Any complex distinct from RNA polymerase including one or more polypeptides capable of binding DNA at promoters or at cis-acting regulatory sequences and regulating transcription. www.broad.mit.e...
Broad OUTER_MEMBRANE View Gene Set 0.002558 25 0.009773 61 Genes annotated by the GO term GO:0019867. The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. www.broad.mit.e...
Broad EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX View Gene Set 0.003966 10 0.01491 62 Genes annotated by the GO term GO:0005852. A complex of several polypeptides that plays at least two important roles in protein synthesis: First eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. www.broad.mit.e...
Broad MITOCHONDRIAL_RESPIRATORY_CHAIN View Gene Set 0.004299 24 0.0159 63 Genes annotated by the GO term GO:0005746. The protein complexes that form the mitochondrial electron transport system (the respiratory chain). Complexes I III and IV can transport protons if embedded in an oriented membrane such as an intact mitochondrial inner membrane. www.broad.mit.e...
Broad NADH_DEHYDROGENASE_COMPLEX View Gene Set 0.005082 15 0.01794 64 Genes annotated by the GO term GO:0030964. An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyses the transfer of a pair of electrons from NADH to a quinone. www.broad.mit.e...
Broad MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I View Gene Set 0.005082 15 0.01794 64 Genes annotated by the GO term GO:0005747. A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits including NADH dehydrogenase (ubiquinone) flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III) and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. www.broad.mit.e...
Broad RESPIRATORY_CHAIN_COMPLEX_I View Gene Set 0.005082 15 0.01794 64 Genes annotated by the GO term GO:0045271. Respiratory chain complex I is an enzyme of the respiratory chain. It consists of at least 34 polypeptide chains and is L-shaped with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex. www.broad.mit.e...
Broad ORGANELLE_MEMBRANE View Gene Set 0.005394 290 0.01876 67 Genes annotated by the GO term GO:0031090. The lipid bilayer surrounding an organelle. www.broad.mit.e...
Broad CENTROSOME View Gene Set 0.006135 55 0.02102 68 Genes annotated by the GO term GO:0005813. A structure comprised of a core structure (in most organisms a pair of centrioles) and peripheral material from which a microtubule-based structure such as a spindle apparatus is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells though in animal cells it changes continually during the cell-division cycle. www.broad.mit.e...
Broad CHROMOSOMEPERICENTRIC_REGION View Gene Set 0.006628 31 0.02238 69 Genes annotated by the GO term GO:0000775. The central region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes this region corresponds to a single area of the chromosome whereas in holocentric chromosomes it is evenly distributed along the chromosome. www.broad.mit.e...
Broad NUCLEAR_SPECK View Gene Set 0.007105 10 0.02365 70 Genes annotated by the GO term GO:0016607. A discrete extra-nucleolar subnuclear domain 20-50 in number in which splicing factors are seen to be localized by immunofluorescence microscopy. www.broad.mit.e...
Broad REPLICATION_FORK View Gene Set 0.007376 18 0.02387 71 Genes annotated by the GO term GO:0005657. The Y-shaped region of a replicating DNA molecule resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. www.broad.mit.e...
Broad NUCLEAR_CHROMATIN View Gene Set 0.007347 14 0.02387 71 Genes annotated by the GO term GO:0000790. The ordered and organized complex of DNA and protein that forms the chromosome in the nucleus. www.broad.mit.e...
Broad SPINDLE_MICROTUBULE View Gene Set 0.01213 15 0.0387 73 Genes annotated by the GO term GO:0005876. Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. www.broad.mit.e...
Broad SPINDLE View Gene Set 0.01313 37 0.04135 74 Genes annotated by the GO term GO:0005819. The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. www.broad.mit.e...

Gene Set Collection: Broad.c5.MF

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad RNA_BINDING View Gene Set 2.396e-15 236 9.49e-13 1 Genes annotated by the GO term GO:0003723. Interacting selectively with an RNA molecule or a portion thereof. www.broad.mit.e...
Broad TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING View Gene Set 1.732e-09 39 3.43e-07 2 Genes annotated by the GO term GO:0008135. Functions during translation by binding nucleic acids during polypeptide synthesis at the ribosome. www.broad.mit.e...
Broad TRANSLATION_REGULATOR_ACTIVITY View Gene Set 1.733e-08 41 2.287e-06 3 Genes annotated by the GO term GO:0045182. Any substance involved in the initiation activation perpetuation repression or termination of polypeptide synthesis at the ribosome. www.broad.mit.e...
Broad TRANSLATION_INITIATION_FACTOR_ACTIVITY View Gene Set 9.572e-08 24 9.476e-06 4 Genes annotated by the GO term GO:0003743. Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. www.broad.mit.e...
Broad LIGASE_ACTIVITY View Gene Set 6.077e-07 97 4.813e-05 5 Genes annotated by the GO term GO:0016874. Catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. www.broad.mit.e...
Broad LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS View Gene Set 1.008e-06 14 5.021e-05 6 Genes annotated by the GO term GO:0016875. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. www.broad.mit.e...
Broad STRUCTURE_SPECIFIC_DNA_BINDING View Gene Set 1.014e-06 55 5.021e-05 6 Genes annotated by the GO term GO:0043566. Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. www.broad.mit.e...
Broad DNA_BINDING View Gene Set 8.24e-07 587 5.021e-05 6 Genes annotated by the GO term GO:0003677. Interacting selectively with DNA (deoxyribonucleic acid). www.broad.mit.e...
Broad SINGLE_STRANDED_DNA_BINDING View Gene Set 1.075e-05 34 0.0004728 9 Genes annotated by the GO term GO:0003697. Interacting selectively with single-stranded DNA. www.broad.mit.e...
Broad NUCLEOTIDYLTRANSFERASE_ACTIVITY View Gene Set 1.928e-05 47 0.0007636 10 Genes annotated by the GO term GO:0016779. Catalysis of the transfer of a nucleotidyl group to a reactant. www.broad.mit.e...
Broad HELICASE_ACTIVITY View Gene Set 3.278e-05 49 0.00118 11 Genes annotated by the GO term GO:0004386. Catalysis of the unwinding of a DNA or RNA duplex. www.broad.mit.e...
Broad RNA_POLYMERASE_ACTIVITY View Gene Set 3.696e-05 16 0.00122 12 Genes annotated by the GO term GO:0034062. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template. www.broad.mit.e...
Broad DOUBLE_STRANDED_DNA_BINDING View Gene Set 4.247e-05 32 0.001294 13 Genes annotated by the GO term GO:0003690. Interacting selectively with double-stranded DNA. www.broad.mit.e...
Broad ATP_DEPENDENT_HELICASE_ACTIVITY View Gene Set 5.897e-05 26 0.001668 14 Genes annotated by the GO term GO:0008026. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the unwinding of a DNA or RNA helix. www.broad.mit.e...
Broad METHYLTRANSFERASE_ACTIVITY View Gene Set 0.0001273 36 0.003362 15 Genes annotated by the GO term GO:0008168. Catalysis of the transfer of a methyl group to an acceptor molecule. www.broad.mit.e...
Broad ATP_DEPENDENT_RNA_HELICASE_ACTIVITY View Gene Set 0.000141 17 0.003489 16 Genes annotated by the GO term GO:0004004. Catalysis of the reaction: ATP + H2O = ADP + phosphate driving the unwinding of an RNA helix. www.broad.mit.e...
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS View Gene Set 0.000169 37 0.003937 17 Genes annotated by the GO term GO:0016741. Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor). www.broad.mit.e...
Broad RNA_HELICASE_ACTIVITY View Gene Set 0.000241 24 0.004803 18 Genes annotated by the GO term GO:0003724. Catalysis of the unwinding of an RNA helix. www.broad.mit.e...
Broad LIGASE_ACTIVITY_FORMING_CARBON_NITROGEN_BONDS View Gene Set 0.0002193 68 0.004803 18 Genes annotated by the GO term GO:0016879. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. www.broad.mit.e...
Broad RNA_SPLICING_FACTOR_ACTIVITYTRANSESTERIFICATION_MECHANISM View Gene Set 0.0002426 14 0.004803 18 Genes annotated by the GO term GO:0031202. An activity which binds RNA and functions to assist splicing of substrate RNA(s) by facilitating the formation and stabilization of a catalytic conformation in which the splice junctions of the RNA(s) to be spliced are positioned for a transesterification reaction that occurs between two sites within the RNA(s) to be spliced. www.broad.mit.e...
Broad MRNA_BINDING View Gene Set 0.0002565 22 0.004837 21 Genes annotated by the GO term GO:0003729. Interacting selectively with pre-messenger RNA (pre-mRNA) or messenger RNA (mRNA). www.broad.mit.e...
Broad HISTONE_ACETYLTRANSFERASE_ACTIVITY View Gene Set 0.000291 16 0.00501 22 Genes annotated by the GO term GO:0004402. Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone. www.broad.mit.e...
Broad RNA_DEPENDENT_ATPASE_ACTIVITY View Gene Set 0.0002807 18 0.00501 22 Genes annotated by the GO term GO:0008186. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of RNA; drives another reaction. www.broad.mit.e...
Broad HYDROLASE_ACTIVITY_HYDROLYZING_N_GLYCOSYL_COMPOUNDS View Gene Set 0.000512 10 0.008214 24 Genes annotated by the GO term GO:0016799. Catalysis of the hydrolysis of any N-glycosyl bond. www.broad.mit.e...
Broad CHROMATIN_BINDING View Gene Set 0.0005185 32 0.008214 24 Genes annotated by the GO term GO:0003682. Interacting selectively with chromatin the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. www.broad.mit.e...
Broad ATPASE_ACTIVITY View Gene Set 0.0009349 109 0.01424 26 Genes annotated by the GO term GO:0016887. Catalysis of the reaction: ATP + H2O = ADP + phosphate. May or may not be coupled to another reaction. www.broad.mit.e...
Broad RIBONUCLEASE_ACTIVITY View Gene Set 0.001257 25 0.01844 27 Genes annotated by the GO term GO:0004540. Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. www.broad.mit.e...
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS View Gene Set 0.001434 56 0.01958 28 Genes annotated by the GO term GO:0016746. Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). www.broad.mit.e...
Broad HORMONE_RECEPTOR_BINDING View Gene Set 0.001395 29 0.01958 28 Genes annotated by the GO term GO:0051427. Interacting selectively with a receptor for hormones. www.broad.mit.e...
Broad UNFOLDED_PROTEIN_BINDING View Gene Set 0.002085 41 0.02753 30 Genes annotated by the GO term GO:0051082. Interacting selectively with an unfolded protein. www.broad.mit.e...
Broad NUCLEAR_HORMONE_RECEPTOR_BINDING View Gene Set 0.002486 28 0.03175 31 Genes annotated by the GO term GO:0035257. Interacting selectively with a nuclear hormone receptor a ligand-dependent receptor found in the nucleus of the cell. www.broad.mit.e...
Broad ACID_AMINO_ACID_LIGASE_ACTIVITY View Gene Set 0.002803 57 0.03468 32 Genes annotated by the GO term GO:0016881. Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. www.broad.mit.e...
Broad ACETYLTRANSFERASE_ACTIVITY View Gene Set 0.003074 23 0.03689 33 Genes annotated by the GO term GO:0016407. Catalysis of the transfer of an acetyl group to an acceptor molecule. www.broad.mit.e...
Broad STEROID_HORMONE_RECEPTOR_BINDING View Gene Set 0.003408 10 0.03878 34 Genes annotated by the GO term GO:0035258. Interacting selectively with a steroid hormone receptor. www.broad.mit.e...
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_PENTOSYL_GROUPS View Gene Set 0.003507 19 0.03878 34 Genes annotated by the GO term GO:0016763. Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). www.broad.mit.e...
Broad ENDONUCLEASE_ACTIVITY_GO_0016893 View Gene Set 0.003525 11 0.03878 34 Genes annotated by the GO term GO:0016893. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. www.broad.mit.e...
Broad DNA_POLYMERASE_ACTIVITY View Gene Set 0.004051 18 0.04335 37 Genes annotated by the GO term GO:0034061. Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and primer. www.broad.mit.e...
Broad DAMAGED_DNA_BINDING View Gene Set 0.004794 21 0.04995 38 Genes annotated by the GO term GO:0003684. Interacting selectively with damaged DNA. www.broad.mit.e...

Gene Set Collection: PMID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
PMID 15635413 View Gene Set 3.744e-53 421 9.386e-50 1 Nucleolar proteome dynamics. www.ncbi.nlm.ni...
PMID 15302935 View Gene Set 1.413e-37 773 1.771e-34 2 Large-scale characterization of HeLa cell nuclear phosphoproteins. www.ncbi.nlm.ni...
PMID 17643375 View Gene Set 1.963e-35 391 1.64e-32 3 Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. www.ncbi.nlm.ni...
PMID 12429849 View Gene Set 4.086e-34 106 2.561e-31 4 Functional proteomic analysis of human nucleolus. www.ncbi.nlm.ni...
PMID 11790298 View Gene Set 2.499e-31 208 1.253e-28 5 Directed proteomic analysis of the human nucleolus. www.ncbi.nlm.ni...
PMID 12226669 View Gene Set 1.8e-26 108 7.521e-24 6 Comprehensive proteomic analysis of the human spliceosome. www.ncbi.nlm.ni...
PMID 12706105 View Gene Set 2.073e-23 182 7.424e-21 7 Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. www.ncbi.nlm.ni...
PMID 16565220 View Gene Set 3.043e-20 210 9.537e-18 8 Phosphoproteome analysis of the human mitotic spindle. www.ncbi.nlm.ni...
PMID 16964243 View Gene Set 8.41e-20 504 2.343e-17 9 A probability-based approach for high-throughput protein phosphorylation analysis and site localization. www.ncbi.nlm.ni...
PMID 11991638 View Gene Set 8.081e-19 74 2.026e-16 10 Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. www.ncbi.nlm.ni...
PMID 11543634 View Gene Set 1.085e-17 58 2.473e-15 11 The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. www.ncbi.nlm.ni...
PMID 14559993 View Gene Set 2.869e-16 51 5.995e-14 12 Regulation of alternative splicing by SRrp86 and its interacting proteins. www.ncbi.nlm.ni...
PMID 20085707 View Gene Set 3.428e-15 42 6.61e-13 13 Aire's partners in the molecular control of immunological tolerance. www.ncbi.nlm.ni...
PMID 11080476 View Gene Set 9.691e-13 87 1.735e-10 14 Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. www.ncbi.nlm.ni...
PMID 15231747 View Gene Set 1.936e-12 212 3.236e-10 15 A protein interaction framework for human mRNA degradation. www.ncbi.nlm.ni...
PMID 17148452 View Gene Set 1.823e-11 87 2.856e-09 16 Characterization of the interactome of the human MutL homologues MLH1 PMS1 and PMS2. www.ncbi.nlm.ni...
PMID 11279123 View Gene Set 3.056e-11 31 4.506e-09 17 The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 14657027 View Gene Set 5.179e-11 74 7.213e-09 18 Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. www.ncbi.nlm.ni...
PMID 11689053 View Gene Set 5.759e-11 70 7.599e-09 19 Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA. www.ncbi.nlm.ni...
PMID 12228227 View Gene Set 4.433e-10 30 5.44e-08 20 Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1. www.ncbi.nlm.ni...
PMID 12408966 View Gene Set 4.638e-10 76 5.44e-08 20 The human and mouse replication-dependent histone genes. www.ncbi.nlm.ni...
PMID 15782174 View Gene Set 4.774e-10 31 5.44e-08 20 Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. www.ncbi.nlm.ni...
PMID 18162579 View Gene Set 5.553e-10 22 6.053e-08 23 Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. www.ncbi.nlm.ni...
PMID 9439656 View Gene Set 1.028e-09 55 1.031e-07 24 The human histone gene cluster at the D6S105 locus. www.ncbi.nlm.ni...
PMID 9566873 View Gene Set 1.02e-09 74 1.031e-07 24 Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. www.ncbi.nlm.ni...
PMID 15130578 View Gene Set 6.352e-09 22 6.124e-07 26 Why do cells need an assembly machine for RNA-protein complexes? www.ncbi.nlm.ni...
PMID 12171929 View Gene Set 1.169e-08 31 1.085e-06 27 A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. www.ncbi.nlm.ni...
PMID 11551941 View Gene Set 2.691e-08 26 2.41e-06 28 The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. www.ncbi.nlm.ni...
PMID 18063578 View Gene Set 6.705e-08 31 5.797e-06 29 The layered structure of human mitochondrial DNA nucleoids. www.ncbi.nlm.ni...
PMID 10601273 View Gene Set 1.413e-07 21 1.181e-05 30 Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein whereas export is due to a nuclear export signal sequence in glucokinase. www.ncbi.nlm.ni...
PMID 12234937 View Gene Set 1.509e-07 34 1.182e-05 31 Characterization of novel SF3b and 17S U2 snRNP proteins including a human Prp5p homologue and an SF3b DEAD-box protein. www.ncbi.nlm.ni...
PMID 9731529 View Gene Set 1.475e-07 24 1.182e-05 31 Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. www.ncbi.nlm.ni...
PMID 15029244 View Gene Set 1.698e-07 57 1.29e-05 33 Mammalian Cdh1/Fzr mediates its own degradation. www.ncbi.nlm.ni...
PMID 11285280 View Gene Set 2.461e-07 62 1.814e-05 34 Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. www.ncbi.nlm.ni...
PMID 10531003 View Gene Set 2.904e-07 15 2.08e-05 35 Newly assembled snRNPs associate with coiled bodies before speckles suggesting a nuclear snRNP maturation pathway. www.ncbi.nlm.ni...
PMID 17289661 View Gene Set 1.008e-06 35 7.017e-05 36 Molecular composition of IMP1 ribonucleoprotein granules. www.ncbi.nlm.ni...
PMID 12167863 View Gene Set 1.676e-06 43 8.403e-05 37 Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. www.ncbi.nlm.ni...
PMID 12388589 View Gene Set 1.578e-06 17 8.403e-05 37 A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. www.ncbi.nlm.ni...
PMID 12808465 View Gene Set 1.676e-06 43 8.403e-05 37 The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. www.ncbi.nlm.ni...
PMID 12808466 View Gene Set 1.676e-06 43 8.403e-05 37 Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. www.ncbi.nlm.ni...
PMID 12809610 View Gene Set 1.676e-06 43 8.403e-05 37 DNA deamination mediates innate immunity to retroviral infection. www.ncbi.nlm.ni...
PMID 12859895 View Gene Set 1.673e-06 47 8.403e-05 37 Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. www.ncbi.nlm.ni...
PMID 12970355 View Gene Set 1.676e-06 43 8.403e-05 37 The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity. www.ncbi.nlm.ni...
PMID 14527406 View Gene Set 1.676e-06 43 8.403e-05 37 HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. www.ncbi.nlm.ni...
PMID 14528300 View Gene Set 1.676e-06 43 8.403e-05 37 The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. www.ncbi.nlm.ni...
PMID 14528301 View Gene Set 1.676e-06 43 8.403e-05 37 HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. www.ncbi.nlm.ni...
PMID 14557625 View Gene Set 1.676e-06 43 8.403e-05 37 The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15) a cellular inhibitor of virus infectivity. www.ncbi.nlm.ni...
PMID 17363900 View Gene Set 1.319e-06 14 8.403e-05 37 The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. www.ncbi.nlm.ni...
PMID 19710015 View Gene Set 1.364e-06 48 8.403e-05 37 The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor. www.ncbi.nlm.ni...
PMID 9119399 View Gene Set 1.264e-06 35 8.403e-05 37 Human histone gene organization: nonregular arrangement within a large cluster. www.ncbi.nlm.ni...
PMID 19237606 View Gene Set 2.304e-06 84 0.0001111 51 Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. www.ncbi.nlm.ni...
PMID 20496165 View Gene Set 2.279e-06 68 0.0001111 51 Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. www.ncbi.nlm.ni...
PMID 15146077 View Gene Set 2.414e-06 32 0.0001142 53 The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. www.ncbi.nlm.ni...
PMID 14743216 View Gene Set 2.464e-06 132 0.0001144 54 A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. www.ncbi.nlm.ni...
PMID 11076961 View Gene Set 2.565e-06 14 0.0001169 55 Characterization of vertebrate cohesin complexes and their regulation in prophase. www.ncbi.nlm.ni...
PMID 11101529 View Gene Set 2.76e-06 34 0.0001235 56 Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. www.ncbi.nlm.ni...
PMID 10893419 View Gene Set 3.687e-06 41 0.0001271 57 Degradation of HIV-1 integrase by the N-end rule pathway. www.ncbi.nlm.ni...
PMID 11714285 View Gene Set 3.854e-06 11 0.0001271 57 The appended C-domain of human methionyl-tRNA synthetase has a tRNA-sequestering function. www.ncbi.nlm.ni...
PMID 12419264 View Gene Set 3.687e-06 41 0.0001271 57 The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing. www.ncbi.nlm.ni...
PMID 12719574 View Gene Set 3.617e-06 42 0.0001271 57 Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions. www.ncbi.nlm.ni...
PMID 12750511 View Gene Set 3.617e-06 42 0.0001271 57 Hypermutation of HIV-1 DNA in the absence of the Vif protein. www.ncbi.nlm.ni...
PMID 12830140 View Gene Set 3.617e-06 42 0.0001271 57 DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses. www.ncbi.nlm.ni...
PMID 12840737 View Gene Set 3.617e-06 42 0.0001271 57 Good to CU. www.ncbi.nlm.ni...
PMID 12914693 View Gene Set 3.617e-06 42 0.0001271 57 Death by deamination: a novel host restriction system for HIV-1. www.ncbi.nlm.ni...
PMID 12920286 View Gene Set 3.617e-06 42 0.0001271 57 Virology. Weapons of mutational destruction. www.ncbi.nlm.ni...
PMID 14550573 View Gene Set 3.687e-06 41 0.0001271 57 Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits. www.ncbi.nlm.ni...
PMID 14614829 View Gene Set 3.617e-06 42 0.0001271 57 The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G. www.ncbi.nlm.ni...
PMID 16055448 View Gene Set 3.854e-06 11 0.0001271 57 The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex. www.ncbi.nlm.ni...
PMID 8052601 View Gene Set 3.854e-06 11 0.0001271 57 Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit. www.ncbi.nlm.ni...
PMID 8078941 View Gene Set 3.854e-06 11 0.0001271 57 Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer. www.ncbi.nlm.ni...
PMID 8188258 View Gene Set 3.854e-06 11 0.0001271 57 The human EPRS locus (formerly the QARS locus): a gene encoding a class I and a class II aminoacyl-tRNA synthetase. www.ncbi.nlm.ni...
PMID 8449960 View Gene Set 3.854e-06 11 0.0001271 57 Expression of human aspartyl-tRNA synthetase in Escherichia coli. Functional analysis of the N-terminal putative amphiphilic helix. www.ncbi.nlm.ni...
PMID 9079628 View Gene Set 3.687e-06 41 0.0001271 57 HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation. www.ncbi.nlm.ni...
PMID 9278442 View Gene Set 3.854e-06 11 0.0001271 57 Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant. www.ncbi.nlm.ni...
PMID 9811770 View Gene Set 3.617e-06 42 0.0001271 57 An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein. www.ncbi.nlm.ni...
PMID 9846577 View Gene Set 3.617e-06 42 0.0001271 57 Evidence for a newly discovered cellular anti-HIV-1 phenotype. www.ncbi.nlm.ni...
PMID 11714716 View Gene Set 5.069e-06 13 0.000165 77 Gemin5 a novel WD repeat protein component of the SMN complex that binds Sm proteins. www.ncbi.nlm.ni...
PMID 12791985 View Gene Set 5.161e-06 37 0.0001659 78 Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. www.ncbi.nlm.ni...
PMID 10064132 View Gene Set 5.613e-06 14 0.0001781 79 The human H2A and H2B histone gene complement. www.ncbi.nlm.ni...
PMID 11829477 View Gene Set 5.758e-06 13 0.0001805 80 Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex. www.ncbi.nlm.ni...
PMID 14564014 View Gene Set 6.005e-06 47 0.0001836 81 Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. www.ncbi.nlm.ni...
PMID 19270065 View Gene Set 5.938e-06 11 0.0001836 81 MRE11 complex links RECQ5 helicase to sites of DNA damage. www.ncbi.nlm.ni...
PMID 16236267 View Gene Set 6.23e-06 77 0.0001882 83 Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. www.ncbi.nlm.ni...
PMID 15960975 View Gene Set 6.655e-06 28 0.0001986 84 Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. www.ncbi.nlm.ni...
PMID 12791267 View Gene Set 7.117e-06 50 0.0002099 85 Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. www.ncbi.nlm.ni...
PMID 11748230 View Gene Set 8.001e-06 17 0.0002332 86 Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. www.ncbi.nlm.ni...
PMID 12614612 View Gene Set 1.006e-05 19 0.0002899 87 Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. www.ncbi.nlm.ni...
PMID 11877377 View Gene Set 1.198e-05 11 0.0003414 88 SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. www.ncbi.nlm.ni...
PMID 7273846 View Gene Set 1.225e-05 12 0.000345 89 The glucose-lactic acid cycle and gluconeogenesis. www.ncbi.nlm.ni...
PMID 11402041 View Gene Set 1.268e-05 16 0.0003533 90 Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28 S small subunit. www.ncbi.nlm.ni...
PMID 15592455 View Gene Set 1.307e-05 317 0.0003602 91 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. www.ncbi.nlm.ni...
PMID 8811196 View Gene Set 1.48e-05 37 0.0004032 92 Structure and functions of the 20S and 26S proteasomes. www.ncbi.nlm.ni...
PMID 10783165 View Gene Set 1.652e-05 12 0.0004453 93 BASC a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. www.ncbi.nlm.ni...
PMID 20516191 View Gene Set 1.83e-05 12 0.0004881 94 A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins). www.ncbi.nlm.ni...
PMID 15196461 View Gene Set 2.095e-05 11 0.0005528 95 The highly conserved and multifunctional NuA4 HAT complex. www.ncbi.nlm.ni...
PMID 15707391 View Gene Set 2.371e-05 23 0.0006191 96 DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. www.ncbi.nlm.ni...
PMID 10601333 View Gene Set 2.508e-05 12 0.0006483 97 Gemin3: A novel DEAD box protein that interacts with SMN the spinal muscular atrophy gene product and is a component of gems. www.ncbi.nlm.ni...
PMID 16916647 View Gene Set 2.903e-05 76 0.0007425 98 Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. www.ncbi.nlm.ni...
PMID 12588972 View Gene Set 3.055e-05 56 0.0007735 99 Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region. www.ncbi.nlm.ni...
PMID 11279069 View Gene Set 3.242e-05 15 0.0008048 100 Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. www.ncbi.nlm.ni...
PMID 12045100 View Gene Set 3.262e-05 18 0.0008048 100 DNA replication in eukaryotic cells. www.ncbi.nlm.ni...
PMID 18954305 View Gene Set 3.274e-05 13 0.0008048 100 Structural basis and specificity of human otubain 1-mediated deubiquitination. www.ncbi.nlm.ni...
PMID 8724849 View Gene Set 3.648e-05 41 0.0008879 103 Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. www.ncbi.nlm.ni...
PMID 14667819 View Gene Set 4.165e-05 112 0.001004 104 Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. www.ncbi.nlm.ni...
PMID 17456004 View Gene Set 4.356e-05 17 0.00104 105 Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors. www.ncbi.nlm.ni...
PMID 12393188 View Gene Set 5.548e-05 15 0.001312 106 Ku antigen an origin-specific binding protein that associates with replication proteins is required for mammalian DNA replication. www.ncbi.nlm.ni...
PMID 11713266 View Gene Set 6.147e-05 12 0.00144 107 The methylosome a 20S complex containing JBP1 and pICln produces dimethylarginine-modified Sm proteins. www.ncbi.nlm.ni...
PMID 15647280 View Gene Set 6.251e-05 17 0.001451 108 The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. www.ncbi.nlm.ni...
PMID 10725331 View Gene Set 6.814e-05 14 0.001567 109 Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. www.ncbi.nlm.ni...
PMID 11095689 View Gene Set 7.248e-05 17 0.001652 110 The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase. www.ncbi.nlm.ni...
PMID 12391170 View Gene Set 7.451e-05 18 0.001683 111 Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits. www.ncbi.nlm.ni...
PMID 16319397 View Gene Set 8.555e-05 20 0.001915 112 Characterization of histone H2A and H2B variants and their post-translational modifications by mass spectrometry. www.ncbi.nlm.ni...
PMID 14966270 View Gene Set 9.034e-05 19 0.001969 113 Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. www.ncbi.nlm.ni...
PMID 15146057 View Gene Set 8.979e-05 10 0.001969 113 The entire Nup107-160 complex including three new members is targeted as one entity to kinetochores in mitosis. www.ncbi.nlm.ni...
PMID 19596235 View Gene Set 8.9e-05 85 0.001969 113 Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. www.ncbi.nlm.ni...
PMID 12837248 View Gene Set 9.124e-05 22 0.001972 116 The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. www.ncbi.nlm.ni...
PMID 20226869 View Gene Set 9.34e-05 25 0.002001 117 Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations. www.ncbi.nlm.ni...
PMID 16713563 View Gene Set 0.0001029 19 0.002186 118 Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. www.ncbi.nlm.ni...
PMID 8590280 View Gene Set 0.0001052 41 0.002216 119 Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. www.ncbi.nlm.ni...
PMID 1574589 View Gene Set 0.0001184 11 0.002473 120 De novo purine nucleotide biosynthesis. www.ncbi.nlm.ni...
PMID 15504738 View Gene Set 0.0001224 19 0.002537 121 Genes affecting the cell cycle growth maintenance and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. www.ncbi.nlm.ni...
PMID 12628926 View Gene Set 0.0001353 15 0.002773 122 Purification and functional characterization of the human N-CoR complex: the roles of HDAC3 TBL1 and TBLR1. www.ncbi.nlm.ni...
PMID 15226314 View Gene Set 0.000136 20 0.002773 122 Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. www.ncbi.nlm.ni...
PMID 11719186 View Gene Set 0.0001403 17 0.002837 124 AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. www.ncbi.nlm.ni...
PMID 17577209 View Gene Set 0.0001447 28 0.002901 125 The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing. www.ncbi.nlm.ni...
PMID 12611891 View Gene Set 0.000153 40 0.003044 126 The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. www.ncbi.nlm.ni...
PMID 15461802 View Gene Set 0.000168 293 0.003316 127 A genome annotation-driven approach to cloning the human ORFeome. www.ncbi.nlm.ni...
PMID 11060040 View Gene Set 0.0001867 15 0.003647 128 Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. www.ncbi.nlm.ni...
PMID 12065586 View Gene Set 0.0001877 14 0.003647 128 Identification and characterization of Gemin7 a novel component of the survival of motor neuron complex. www.ncbi.nlm.ni...
PMID 16283522 View Gene Set 0.0001935 18 0.003732 130 Inhibition of core histones acetylation by carcinogenic nickel(II). www.ncbi.nlm.ni...
PMID 10608806 View Gene Set 0.0001995 25 0.003819 131 Substrate specificities and identification of putative substrates of ATM kinase family members. www.ncbi.nlm.ni...
PMID 17220478 View Gene Set 0.0002018 63 0.003832 132 Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells. www.ncbi.nlm.ni...
PMID 20522537 View Gene Set 0.0002084 73 0.003927 133 Variation within DNA repair pathway genes and risk of multiple sclerosis. www.ncbi.nlm.ni...
PMID 16387653 View Gene Set 0.0002287 42 0.004278 134 ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. www.ncbi.nlm.ni...
PMID 15823041 View Gene Set 0.0002416 13 0.004487 135 Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes. www.ncbi.nlm.ni...
PMID 15644312 View Gene Set 0.0002548 10 0.004697 136 Dissection of the mitochondrial import and assembly pathway for human Tom40. www.ncbi.nlm.ni...
PMID 12930902 View Gene Set 0.0002656 11 0.004825 137 The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. www.ncbi.nlm.ni...
PMID 14527413 View Gene Set 0.0002637 12 0.004825 137 Nonsense-mediated mRNA decay in mammalian cells involves decapping deadenylating and exonucleolytic activities. www.ncbi.nlm.ni...
PMID 9878398 View Gene Set 0.000271 13 0.004888 139 Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. www.ncbi.nlm.ni...
PMID 1403646 View Gene Set 0.000298 17 0.005336 140 The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC. www.ncbi.nlm.ni...
PMID 9878551 View Gene Set 0.0003087 34 0.005489 141 cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. www.ncbi.nlm.ni...
PMID 11812149 View Gene Set 0.000312 13 0.005509 142 Protein-protein interactions of hCsl4p with other human exosome subunits. www.ncbi.nlm.ni...
PMID 15779907 View Gene Set 0.0003225 12 0.005653 143 Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. www.ncbi.nlm.ni...
PMID 9763677 View Gene Set 0.0003383 15 0.00589 144 Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. www.ncbi.nlm.ni...
PMID 20508983 View Gene Set 0.0003432 102 0.005933 145 Centrosome-related genes genetic variation and risk of breast cancer. www.ncbi.nlm.ni...
PMID 18377426 View Gene Set 0.0003475 20 0.005968 146 Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex. www.ncbi.nlm.ni...
PMID 19209188 View Gene Set 0.0003548 13 0.006051 147 Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study. www.ncbi.nlm.ni...
PMID 16307923 View Gene Set 0.0003873 23 0.00656 148 Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. www.ncbi.nlm.ni...
PMID 12757711 View Gene Set 0.0004189 18 0.007048 149 Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. www.ncbi.nlm.ni...
PMID 10436018 View Gene Set 0.0004324 15 0.007221 150 The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells. www.ncbi.nlm.ni...
PMID 12419256 View Gene Set 0.0004349 12 0.007221 150 Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring. www.ncbi.nlm.ni...
PMID 19064571 View Gene Set 0.0004415 75 0.007281 152 Polymorphisms in mitochondrial genes and prostate cancer risk. www.ncbi.nlm.ni...
PMID 9472028 View Gene Set 0.0004492 12 0.00736 153 SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. www.ncbi.nlm.ni...
PMID 10373521 View Gene Set 0.0004569 13 0.007438 154 Transcriptional cofactor CA150 regulates RNA polymerase II elongation in a TATA-box-dependent manner. www.ncbi.nlm.ni...
PMID 10725406 View Gene Set 0.000477 13 0.007714 155 BRCA1 interaction with RNA polymerase II reveals a role for hRPB2 and hRPB10alpha in activated transcription. www.ncbi.nlm.ni...
PMID 7638159 View Gene Set 0.000494 13 0.007939 156 Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular cofactors and Tat. www.ncbi.nlm.ni...
PMID 10851237 View Gene Set 0.0005007 11 0.007995 157 Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). www.ncbi.nlm.ni...
PMID 15010469 View Gene Set 0.0005231 15 0.0083 158 Phosphorylation of histone H2A inhibits transcription on chromatin templates. www.ncbi.nlm.ni...
PMID 11310559 View Gene Set 0.0005474 17 0.008631 159 Identification of nuclear-import and cell-cycle regulatory proteins that bind to prothymosin alpha. www.ncbi.nlm.ni...
PMID 15078818 View Gene Set 0.0005987 11 0.009322 160 Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo. www.ncbi.nlm.ni...
PMID 16702407 View Gene Set 0.0005987 11 0.009322 160 DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A. www.ncbi.nlm.ni...
PMID 12221105 View Gene Set 0.0006109 16 0.009396 162 Transcriptional activators differ in their abilities to control alternative splicing. www.ncbi.nlm.ni...
PMID 14519125 View Gene Set 0.0006088 12 0.009396 162 Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3. www.ncbi.nlm.ni...
PMID 15009096 View Gene Set 0.0006609 39 0.0101 164 Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex while BMI-1 is transiently co-localized with the centromeric region in interphase. www.ncbi.nlm.ni...
PMID 17158748 View Gene Set 0.0006896 13 0.01042 165 The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity. www.ncbi.nlm.ni...
PMID 18809582 View Gene Set 0.0006876 25 0.01042 165 Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. www.ncbi.nlm.ni...
PMID 17203305 View Gene Set 0.0007256 12 0.01089 167 Genetic variation in the base excision repair pathway and bladder cancer risk. www.ncbi.nlm.ni...
PMID 11205743 View Gene Set 0.0007314 15 0.01091 168 Polo-like kinase interacts with proteasomes and regulates their activity. www.ncbi.nlm.ni...
PMID 11914277 View Gene Set 0.0007487 38 0.01104 169 miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. www.ncbi.nlm.ni...
PMID 15456888 View Gene Set 0.000747 24 0.01104 169 The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. www.ncbi.nlm.ni...
PMID 10318877 View Gene Set 0.0007641 10 0.0112 171 Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex. www.ncbi.nlm.ni...
PMID 9822659 View Gene Set 0.0007724 11 0.01126 172 Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3. www.ncbi.nlm.ni...
PMID 12732143 View Gene Set 0.0007921 14 0.01141 173 The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. www.ncbi.nlm.ni...
PMID 18270339 View Gene Set 0.000792 57 0.01141 173 Comprehensive analysis of DNA repair gene variants and risk of meningioma. www.ncbi.nlm.ni...
PMID 9111189 View Gene Set 0.0008076 16 0.01157 175 Which DNA polymerases are used for DNA-repair in eukaryotes? www.ncbi.nlm.ni...
PMID 11110791 View Gene Set 0.0008431 12 0.01201 176 Three novel components of the human exosome. www.ncbi.nlm.ni...
PMID 15232106 View Gene Set 0.0008519 30 0.01207 177 Self-assembling protein microarrays. www.ncbi.nlm.ni...
PMID 16239144 View Gene Set 0.0009157 16 0.01287 178 Integrator a multiprotein mediator of small nuclear RNA processing associates with the C-terminal repeat of RNA polymerase II. www.ncbi.nlm.ni...
PMID 16627869 View Gene Set 0.0009186 17 0.01287 178 Quantitative proteomic analysis of post-translational modifications of human histones. www.ncbi.nlm.ni...
PMID 1916825 View Gene Set 0.001053 13 0.01466 180 Isolation and characterization of two human H1 histone genes within clusters of core histone genes. www.ncbi.nlm.ni...
PMID 14733938 View Gene Set 0.001192 13 0.01651 181 Protein-protein interactions among human 20S proteasome subunits and proteassemblin. www.ncbi.nlm.ni...
PMID 14729942 View Gene Set 0.001259 18 0.01734 182 Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line. www.ncbi.nlm.ni...
PMID 15324660 View Gene Set 0.001323 242 0.01812 183 Proteomic functional and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. www.ncbi.nlm.ni...
PMID 12788944 View Gene Set 0.001345 11 0.01822 184 The association of the human PM/Scl-75 autoantigen with the exosome is dependent on a newly identified N terminus. www.ncbi.nlm.ni...
PMID 9150948 View Gene Set 0.001339 15 0.01822 184 A two-dimensional gel database of human colon carcinoma proteins. www.ncbi.nlm.ni...
PMID 11149922 View Gene Set 0.00138 14 0.01861 186 A functional interaction between the survival motor neuron complex and RNA polymerase II. www.ncbi.nlm.ni...
PMID 12620389 View Gene Set 0.00141 23 0.0188 187 Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis. www.ncbi.nlm.ni...
PMID 15616580 View Gene Set 0.001405 13 0.0188 187 Histone modifications defining active genes persist after transcriptional and mitotic inactivation. www.ncbi.nlm.ni...
PMID 10069959 View Gene Set 0.001577 12 0.02028 189 Human immunodeficiency virus type 1 Tat-dependent activation of an arrested RNA polymerase II elongation complex. www.ncbi.nlm.ni...
PMID 10983978 View Gene Set 0.001555 10 0.02028 189 Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. www.ncbi.nlm.ni...
PMID 12126615 View Gene Set 0.001577 12 0.02028 189 A bimolecular mechanism of HIV-1 Tat protein interaction with RNA polymerase II transcription elongation complexes. www.ncbi.nlm.ni...
PMID 2190099 View Gene Set 0.001577 12 0.02028 189 Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein. www.ncbi.nlm.ni...
PMID 8637904 View Gene Set 0.001577 12 0.02028 189 Human immunodeficiency virus type-1 Tat is an integral component of the activated transcription-elongation complex. www.ncbi.nlm.ni...
PMID 8876177 View Gene Set 0.001577 12 0.02028 189 Trans-activation by human immunodeficiency virus Tat protein requires the C-terminal domain of RNA polymerase II. www.ncbi.nlm.ni...
PMID 8910388 View Gene Set 0.001577 12 0.02028 189 Requirements for RNA polymerase II carboxyl-terminal domain for activated transcription of human retroviruses human T-cell lymphotropic virus I and HIV-1. www.ncbi.nlm.ni...
PMID 12634356 View Gene Set 0.00161 15 0.02047 196 Human immunodeficiency virus type 1 (HIV-1) Vpr enhances expression from unintegrated HIV-1 DNA. www.ncbi.nlm.ni...
PMID 12642036 View Gene Set 0.00161 15 0.02047 196 HIV-1 Vpr binding to HIV-1 LTR C/EBP cis-acting elements and adjacent regions is sequence-specific. www.ncbi.nlm.ni...
PMID 17478428 View Gene Set 0.001617 10 0.02047 196 A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints. www.ncbi.nlm.ni...
PMID 11547919 View Gene Set 0.001639 17 0.02065 199 Multiple modes of transcriptional regulation by the HIV-1 Tat transactivator. www.ncbi.nlm.ni...
PMID 8995409 View Gene Set 0.001858 11 0.02318 200 Conservation and diversity of eukaryotic translation initiation factor eIF3. www.ncbi.nlm.ni...

Gene Set Collection: ChromosomalTiles5Mb

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null chr3_45-50Mb View Gene Set 2.395e-05 72 0.02668 1 Genomic tile: chr3 ; 45000001-50000001 Mb genome.ucsc.edu...
Null chr12_120-125Mb View Gene Set 9.43e-05 44 0.04886 2 Genomic tile: chr12 ; 120000001-125000001 Mb genome.ucsc.edu...
Null chr16_85-90Mb View Gene Set 0.0001316 43 0.04886 2 Genomic tile: chr16 ; 85000001-90000001 Mb genome.ucsc.edu...
Null chr17_0-5Mb View Gene Set 0.0001768 65 0.04923 4 Genomic tile: chr17 ; 1-5000001 Mb genome.ucsc.edu...

Gene Set Collection: Prosite

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null PS50102 View Gene Set 4.99e-21 229 3.668e-18 1 RRM expasy.org/pros...
Null PS51194 View Gene Set 6.488e-12 113 2.384e-09 2 HELICASE_CTER expasy.org/pros...
Null PS51192 View Gene Set 2.19e-11 112 5.367e-09 3 HELICASE_ATP_BIND_1 expasy.org/pros...
Null PS51195 View Gene Set 2.528e-09 37 4.645e-07 4 Q_MOTIF expasy.org/pros...
Null PS50862 View Gene Set 4.032e-07 18 5.927e-05 5 AA_TRNA_LIGASE_II expasy.org/pros...
Null PS00039 View Gene Set 6.321e-07 27 6.637e-05 6 DEAD_ATP_HELICASE expasy.org/pros...
Null PS00178 View Gene Set 5.832e-07 15 6.637e-05 6 AA_TRNA_LIGASE_I expasy.org/pros...
Null PS50082 View Gene Set 2.256e-06 233 0.0002073 8 WD_REPEATS_2 expasy.org/pros...
Null PS00047 View Gene Set 3.924e-06 14 0.0002884 9 HISTONE_H4 expasy.org/pros...
Null PS00678 View Gene Set 3.574e-06 168 0.0002884 9 WD_REPEATS_1 expasy.org/pros...
Null PS50294 View Gene Set 6.255e-06 245 0.0004179 11 WD_REPEATS_REGION expasy.org/pros...
Null PS00357 View Gene Set 2.371e-05 19 0.001452 12 HISTONE_H2B expasy.org/pros...
Null PS00674 View Gene Set 2.656e-05 29 0.001502 13 AAA expasy.org/pros...
Null PS50166 View Gene Set 3.93e-05 13 0.002063 14 IMPORTIN_B_NT expasy.org/pros...
Null PS00847 View Gene Set 7.45e-05 6 0.00365 15 MCM_1 expasy.org/pros...
Null PS00046 View Gene Set 0.0001566 21 0.006059 16 HISTONE_H2A expasy.org/pros...
Null PS00750 View Gene Set 0.0001501 9 0.006059 16 TCP1_1 expasy.org/pros...
Null PS00751 View Gene Set 0.0001501 9 0.006059 16 TCP1_2 expasy.org/pros...
Null PS00995 View Gene Set 0.0001501 9 0.006059 16 TCP1_3 expasy.org/pros...
Null PS50051 View Gene Set 0.0002751 8 0.009948 20 MCM_2 expasy.org/pros...
Null PS50812 View Gene Set 0.0002842 22 0.009948 20 PWWP expasy.org/pros...
Null PS50280 View Gene Set 0.0003155 47 0.01054 22 SET expasy.org/pros...
Null PS50016 View Gene Set 0.0004104 78 0.01311 23 ZF_PHD_2 expasy.org/pros...
Null PS00469 View Gene Set 0.0004599 6 0.01408 24 NDP_KINASES expasy.org/pros...
Null PS51189 View Gene Set 0.0008266 9 0.02337 25 FAT expasy.org/pros...
Null PS51190 View Gene Set 0.0008266 9 0.02337 25 FATC expasy.org/pros...
Null PS50800 View Gene Set 0.001387 23 0.03775 27 SAP expasy.org/pros...
Null PS51391 View Gene Set 0.001574 8 0.04131 28 CID expasy.org/pros...
Null PS51375 View Gene Set 0.001694 7 0.04294 29 PPR expasy.org/pros...
Null PS01358 View Gene Set 0.001945 25 0.04613 30 ZF_RANBP2_1 expasy.org/pros...
Null PS50199 View Gene Set 0.001945 23 0.04613 30 ZF_RANBP2_2 expasy.org/pros...

Gene Set Collection: Enzyme

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null EC:1.6.5.3 View Gene Set 0.0002846 43 0.02347 1 NADH dehydrogenase (ubiquinone) expasy.org/enzy...
Null EC:1.6.99.3 View Gene Set 0.000315 35 0.02347 1 NADH dehydrogenase expasy.org/enzy...
Null EC:3.4.25.1 View Gene Set 0.0004457 20 0.02347 1 Proteasome endopeptidase complex expasy.org/enzy...
Null EC:2.1.1.43 View Gene Set 0.0007569 19 0.02953 4 Histone-lysine N-methyltransferase expasy.org/enzy...
Null EC:3.6.4.13 View Gene Set 0.0009345 13 0.02953 4 RNA helicase expasy.org/enzy...
Null EC:2.7.7.6 View Gene Set 0.001546 17 0.0407 6 DNA-directed RNA polymerase expasy.org/enzy...

Gene Set Collection: ppi.BIND

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.SNORD3A View Gene Set 0.0001729 9 0.03268 1 Protein-protein-interaction for SNORD3A www.ncbi.nlm.ni...

Gene Set Collection: ppi.BioGRID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.155871 View Gene Set 1.314e-35 236 3.018e-32 1 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 3.901e-21 147 4.481e-18 2 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.SRRM1 View Gene Set 5.564e-13 64 4.26e-10 3 Protein-protein-interaction for SRRM1 www.ncbi.nlm.ni...
Null ppi.SRRM2 View Gene Set 5.637e-10 101 3.237e-07 4 Protein-protein-interaction for SRRM2 www.ncbi.nlm.ni...
Null ppi.KHDRBS2 View Gene Set 4.203e-09 46 1.931e-06 5 Protein-protein-interaction for KHDRBS2 www.ncbi.nlm.ni...
Null ppi.RNPS1 View Gene Set 3.765e-08 38 1.072e-05 6 Protein-protein-interaction for RNPS1 www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 4.049e-08 24 1.072e-05 6 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.72462 View Gene Set 4.202e-08 42 1.072e-05 6 Protein-protein-interaction for 72462 www.ncbi.nlm.ni...
Null ppi.CDT1 View Gene Set 4.098e-08 37 1.072e-05 6 Protein-protein-interaction for CDT1 www.ncbi.nlm.ni...
Null ppi.GPN1 View Gene Set 8.089e-08 27 1.858e-05 10 Protein-protein-interaction for GPN1 www.ncbi.nlm.ni...
Null ppi.RPA1 View Gene Set 1.496e-07 23 3.124e-05 11 Protein-protein-interaction for RPA1 www.ncbi.nlm.ni...
Null ppi.EIF3F View Gene Set 2.157e-07 22 4.129e-05 12 Protein-protein-interaction for EIF3F www.ncbi.nlm.ni...
Null ppi.USP42 View Gene Set 2.591e-07 24 4.579e-05 13 Protein-protein-interaction for USP42 www.ncbi.nlm.ni...
Null ppi.SUMO2 View Gene Set 3.424e-07 50 5.617e-05 14 Protein-protein-interaction for SUMO2 www.ncbi.nlm.ni...
Null ppi.RRP1B View Gene Set 7.892e-07 21 0.0001208 15 Protein-protein-interaction for RRP1B www.ncbi.nlm.ni...
Null ppi.WBP4 View Gene Set 2.049e-06 35 0.0002942 16 Protein-protein-interaction for WBP4 www.ncbi.nlm.ni...
Null ppi.RNU12-2P View Gene Set 3.851e-06 18 0.0004656 17 Protein-protein-interaction for RNU12-2P www.ncbi.nlm.ni...
Null ppi.RNU11 View Gene Set 3.851e-06 18 0.0004656 17 Protein-protein-interaction for RNU11 www.ncbi.nlm.ni...
Null ppi.HIST1H4A View Gene Set 3.785e-06 28 0.0004656 17 Protein-protein-interaction for HIST1H4A www.ncbi.nlm.ni...
Null ppi.UCHL5 View Gene Set 4.269e-06 33 0.0004902 20 Protein-protein-interaction for UCHL5 www.ncbi.nlm.ni...
Null ppi.DDX20 View Gene Set 4.717e-06 17 0.000516 21 Protein-protein-interaction for DDX20 www.ncbi.nlm.ni...
Null ppi.RAD50 View Gene Set 7.387e-06 20 0.0007497 22 Protein-protein-interaction for RAD50 www.ncbi.nlm.ni...
Null ppi.RUVBL2 View Gene Set 7.507e-06 64 0.0007497 22 Protein-protein-interaction for RUVBL2 www.ncbi.nlm.ni...
Null ppi.USP36 View Gene Set 8.643e-06 17 0.0008272 24 Protein-protein-interaction for USP36 www.ncbi.nlm.ni...
Null ppi.WDR77 View Gene Set 1.125e-05 15 0.001017 25 Protein-protein-interaction for WDR77 www.ncbi.nlm.ni...
Null ppi.MED26 View Gene Set 1.151e-05 22 0.001017 25 Protein-protein-interaction for MED26 www.ncbi.nlm.ni...
Null ppi.GIGYF2 View Gene Set 1.31e-05 17 0.001037 27 Protein-protein-interaction for GIGYF2 www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 1.298e-05 40 0.001037 27 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 1.29e-05 43 0.001037 27 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.PSMD13 View Gene Set 1.614e-05 20 0.001236 30 Protein-protein-interaction for PSMD13 www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 1.809e-05 15 0.00134 31 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.MRE11A View Gene Set 1.986e-05 13 0.001425 32 Protein-protein-interaction for MRE11A www.ncbi.nlm.ni...
Null ppi.TERF2 View Gene Set 2.561e-05 9 0.001782 33 Protein-protein-interaction for TERF2 www.ncbi.nlm.ni...
Null ppi.EIF3H View Gene Set 2.746e-05 16 0.001855 34 Protein-protein-interaction for EIF3H www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 2.852e-05 12 0.001871 35 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 4.077e-05 14 0.002601 36 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.WWOX View Gene Set 4.418e-05 19 0.002743 37 Protein-protein-interaction for WWOX www.ncbi.nlm.ni...
Null ppi.USP39 View Gene Set 6.286e-05 15 0.003767 38 Protein-protein-interaction for USP39 www.ncbi.nlm.ni...
Null ppi.RPAP1 View Gene Set 6.396e-05 24 0.003767 38 Protein-protein-interaction for RPAP1 www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 6.696e-05 11 0.003845 40 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.PRMT5 View Gene Set 7.633e-05 31 0.004276 41 Protein-protein-interaction for PRMT5 www.ncbi.nlm.ni...
Null ppi.GIYD2 View Gene Set 8.391e-05 32 0.004589 42 Protein-protein-interaction for GIYD2 www.ncbi.nlm.ni...
Null ppi.GEMIN5 View Gene Set 9.41e-05 11 0.005027 43 Protein-protein-interaction for GEMIN5 www.ncbi.nlm.ni...
Null ppi.UPF2 View Gene Set 9.754e-05 12 0.005092 44 Protein-protein-interaction for UPF2 www.ncbi.nlm.ni...
Null ppi.PDS5A View Gene Set 0.0001023 6 0.005223 45 Protein-protein-interaction for PDS5A www.ncbi.nlm.ni...
Null ppi.SNUPN View Gene Set 0.0001132 10 0.005223 46 Protein-protein-interaction for SNUPN www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 0.0001106 19 0.005223 46 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.CHTF18 View Gene Set 0.0001144 13 0.005223 46 Protein-protein-interaction for CHTF18 www.ncbi.nlm.ni...
Null ppi.UPF3A View Gene Set 0.000116 15 0.005223 46 Protein-protein-interaction for UPF3A www.ncbi.nlm.ni...
Null ppi.TAF10 View Gene Set 0.0001121 27 0.005223 46 Protein-protein-interaction for TAF10 www.ncbi.nlm.ni...
Null ppi.PSMD6 View Gene Set 0.0001096 21 0.005223 46 Protein-protein-interaction for PSMD6 www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 0.0001193 38 0.005272 52 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.POLR1C View Gene Set 0.0001244 6 0.005392 53 Protein-protein-interaction for POLR1C www.ncbi.nlm.ni...
Null ppi.ZBTB9 View Gene Set 0.0001286 16 0.005406 54 Protein-protein-interaction for ZBTB9 www.ncbi.nlm.ni...
Null ppi.USP50 View Gene Set 0.0001294 22 0.005406 54 Protein-protein-interaction for USP50 www.ncbi.nlm.ni...
Null ppi.BRF2 View Gene Set 0.0001366 23 0.005602 56 Protein-protein-interaction for BRF2 www.ncbi.nlm.ni...
Null ppi.NAA38 View Gene Set 0.0001523 21 0.006136 57 Protein-protein-interaction for NAA38 www.ncbi.nlm.ni...
Null ppi.PSMD14 View Gene Set 0.0001654 16 0.006473 58 Protein-protein-interaction for PSMD14 www.ncbi.nlm.ni...
Null ppi.RALYL View Gene Set 0.0001674 12 0.006473 58 Protein-protein-interaction for RALYL www.ncbi.nlm.ni...
Null ppi.RNMTL1 View Gene Set 0.0001747 8 0.006473 58 Protein-protein-interaction for RNMTL1 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 0.0001744 168 0.006473 58 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.BANF1 View Gene Set 0.0001715 34 0.006473 58 Protein-protein-interaction for BANF1 www.ncbi.nlm.ni...
Null ppi.MCPH1 View Gene Set 0.0001958 17 0.007029 63 Protein-protein-interaction for MCPH1 www.ncbi.nlm.ni...
Null ppi.MED13 View Gene Set 0.0001943 10 0.007029 63 Protein-protein-interaction for MED13 www.ncbi.nlm.ni...
Null ppi.SAE1 View Gene Set 0.0002014 10 0.007119 65 Protein-protein-interaction for SAE1 www.ncbi.nlm.ni...
Null ppi.ING3 View Gene Set 0.0002112 10 0.00735 66 Protein-protein-interaction for ING3 www.ncbi.nlm.ni...
Null ppi.HSPA8 View Gene Set 0.0002168 21 0.007433 67 Protein-protein-interaction for HSPA8 www.ncbi.nlm.ni...
Null ppi.TOP1 View Gene Set 0.0002259 10 0.007631 68 Protein-protein-interaction for TOP1 www.ncbi.nlm.ni...
Null ppi.NUP153 View Gene Set 0.0002476 11 0.008241 69 Protein-protein-interaction for NUP153 www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 0.0002659 53 0.008648 70 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.RPAP3 View Gene Set 0.0002673 29 0.008648 70 Protein-protein-interaction for RPAP3 www.ncbi.nlm.ni...
Null ppi.HNRNPL View Gene Set 0.0002766 8 0.008704 72 Protein-protein-interaction for HNRNPL www.ncbi.nlm.ni...
Null ppi.NUP43 View Gene Set 0.0002753 6 0.008704 72 Protein-protein-interaction for NUP43 www.ncbi.nlm.ni...
Null ppi.TTI1 View Gene Set 0.0002868 8 0.008903 74 Protein-protein-interaction for TTI1 www.ncbi.nlm.ni...
Null ppi.PABPC1 View Gene Set 0.0003102 26 0.009254 75 Protein-protein-interaction for PABPC1 www.ncbi.nlm.ni...
Null ppi.PMS2 View Gene Set 0.0003064 14 0.009254 75 Protein-protein-interaction for PMS2 www.ncbi.nlm.ni...
Null ppi.DMAP1 View Gene Set 0.0003118 13 0.009254 75 Protein-protein-interaction for DMAP1 www.ncbi.nlm.ni...
Null ppi.SF3A2 View Gene Set 0.0003143 16 0.009254 75 Protein-protein-interaction for SF3A2 www.ncbi.nlm.ni...
Null ppi.WDR48 View Gene Set 0.0003209 52 0.009331 79 Protein-protein-interaction for WDR48 www.ncbi.nlm.ni...
Null ppi.TAF1D View Gene Set 0.0003574 21 0.01026 80 Protein-protein-interaction for TAF1D www.ncbi.nlm.ni...
Null ppi.CDC7 View Gene Set 0.0003685 7 0.01045 81 Protein-protein-interaction for CDC7 www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 0.0003862 9 0.01056 82 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.NBN View Gene Set 0.0003792 13 0.01056 82 Protein-protein-interaction for NBN www.ncbi.nlm.ni...
Null ppi.AURKA View Gene Set 0.0003846 9 0.01056 82 Protein-protein-interaction for AURKA www.ncbi.nlm.ni...
Null ppi.U2AF2 View Gene Set 0.0004115 14 0.01099 85 Protein-protein-interaction for U2AF2 www.ncbi.nlm.ni...
Null ppi.CDC45 View Gene Set 0.0004096 9 0.01099 85 Protein-protein-interaction for CDC45 www.ncbi.nlm.ni...
Null ppi.TP53BP1 View Gene Set 0.0004281 13 0.0113 87 Protein-protein-interaction for TP53BP1 www.ncbi.nlm.ni...
Null ppi.OTUB1 View Gene Set 0.000439 18 0.01133 88 Protein-protein-interaction for OTUB1 www.ncbi.nlm.ni...
Null ppi.MED24 View Gene Set 0.0004354 20 0.01133 88 Protein-protein-interaction for MED24 www.ncbi.nlm.ni...
Null ppi.ZNF496 View Gene Set 0.0004735 13 0.01209 90 Protein-protein-interaction for ZNF496 www.ncbi.nlm.ni...
Null ppi.CTCF View Gene Set 0.000485 6 0.01224 91 Protein-protein-interaction for CTCF www.ncbi.nlm.ni...
Null ppi.GAR1 View Gene Set 0.0004912 9 0.01226 92 Protein-protein-interaction for GAR1 www.ncbi.nlm.ni...
Null ppi.SRPK2 View Gene Set 0.0005033 7 0.01243 93 Protein-protein-interaction for SRPK2 www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 0.0005464 10 0.01335 94 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.ORC6L View Gene Set 0.0005857 11 0.01416 95 Protein-protein-interaction for ORC6L www.ncbi.nlm.ni...
Null ppi.PRMT1 View Gene Set 0.000595 15 0.01424 96 Protein-protein-interaction for PRMT1 www.ncbi.nlm.ni...
Null ppi.USP14 View Gene Set 0.0006064 22 0.01436 97 Protein-protein-interaction for USP14 www.ncbi.nlm.ni...
Null ppi.DDX24 View Gene Set 0.0006146 20 0.0144 98 Protein-protein-interaction for DDX24 www.ncbi.nlm.ni...
Null ppi.GEMIN6 View Gene Set 0.0006533 7 0.01516 99 Protein-protein-interaction for GEMIN6 www.ncbi.nlm.ni...
Null ppi.MCM6 View Gene Set 0.0006811 6 0.01564 100 Protein-protein-interaction for MCM6 www.ncbi.nlm.ni...
Null ppi.MYC View Gene Set 0.0006954 42 0.01582 101 Protein-protein-interaction for MYC www.ncbi.nlm.ni...
Null ppi.COPS8 View Gene Set 0.0007748 8 0.01742 102 Protein-protein-interaction for COPS8 www.ncbi.nlm.ni...
Null ppi.POLR3H View Gene Set 0.0007812 14 0.01742 102 Protein-protein-interaction for POLR3H www.ncbi.nlm.ni...
Null ppi.MED23 View Gene Set 0.0007939 14 0.01754 104 Protein-protein-interaction for MED23 www.ncbi.nlm.ni...
Null ppi.TOPORS View Gene Set 0.000806 27 0.01759 105 Protein-protein-interaction for TOPORS www.ncbi.nlm.ni...
Null ppi.MED14 View Gene Set 0.0008116 14 0.01759 105 Protein-protein-interaction for MED14 www.ncbi.nlm.ni...
Null ppi.SMAD6 View Gene Set 0.0008196 6 0.01759 107 Protein-protein-interaction for SMAD6 www.ncbi.nlm.ni...
Null ppi.XRN1 View Gene Set 0.0008498 12 0.01791 108 Protein-protein-interaction for XRN1 www.ncbi.nlm.ni...
Null ppi.MED1 View Gene Set 0.0008475 20 0.01791 108 Protein-protein-interaction for MED1 www.ncbi.nlm.ni...
Null ppi.POLR3C View Gene Set 0.0008601 10 0.01796 110 Protein-protein-interaction for POLR3C www.ncbi.nlm.ni...
Null ppi.LSM3 View Gene Set 0.0009006 9 0.01864 111 Protein-protein-interaction for LSM3 www.ncbi.nlm.ni...
Null ppi.SIN3A View Gene Set 0.0009916 104 0.01981 112 Protein-protein-interaction for SIN3A www.ncbi.nlm.ni...
Null ppi.ORC1L View Gene Set 0.0009745 9 0.01981 112 Protein-protein-interaction for ORC1L www.ncbi.nlm.ni...
Null ppi.C20orf20 View Gene Set 0.000986 15 0.01981 112 Protein-protein-interaction for C20orf20 www.ncbi.nlm.ni...
Null ppi.USF2 View Gene Set 0.0009817 13 0.01981 112 Protein-protein-interaction for USF2 www.ncbi.nlm.ni...
Null ppi.CLSPN View Gene Set 0.001023 17 0.02026 116 Protein-protein-interaction for CLSPN www.ncbi.nlm.ni...
Null ppi.KEAP1 View Gene Set 0.001056 21 0.02072 117 Protein-protein-interaction for KEAP1 www.ncbi.nlm.ni...
Null ppi.ESR2 View Gene Set 0.001081 8 0.02086 118 Protein-protein-interaction for ESR2 www.ncbi.nlm.ni...
Null ppi.EXOSC4 View Gene Set 0.001078 9 0.02086 118 Protein-protein-interaction for EXOSC4 www.ncbi.nlm.ni...
Null ppi.OSBPL10 View Gene Set 0.001094 15 0.02094 120 Protein-protein-interaction for OSBPL10 www.ncbi.nlm.ni...
Null ppi.PCNA View Gene Set 0.001127 40 0.0214 121 Protein-protein-interaction for PCNA www.ncbi.nlm.ni...
Null ppi.SUPT16H View Gene Set 0.001251 11 0.02227 122 Protein-protein-interaction for SUPT16H www.ncbi.nlm.ni...
Null ppi.HNRNPH1 View Gene Set 0.001247 9 0.02227 122 Protein-protein-interaction for HNRNPH1 www.ncbi.nlm.ni...
Null ppi.MSH2 View Gene Set 0.001219 16 0.02227 122 Protein-protein-interaction for MSH2 www.ncbi.nlm.ni...
Null ppi.COPS4 View Gene Set 0.00121 12 0.02227 122 Protein-protein-interaction for COPS4 www.ncbi.nlm.ni...
Null ppi.POLR2A View Gene Set 0.001239 25 0.02227 122 Protein-protein-interaction for POLR2A www.ncbi.nlm.ni...
Null ppi.BRCC3 View Gene Set 0.001212 22 0.02227 122 Protein-protein-interaction for BRCC3 www.ncbi.nlm.ni...
Null ppi.ATRIP View Gene Set 0.001197 9 0.02227 122 Protein-protein-interaction for ATRIP www.ncbi.nlm.ni...
Null ppi.MDC1 View Gene Set 0.001248 20 0.02227 122 Protein-protein-interaction for MDC1 www.ncbi.nlm.ni...
Null ppi.PGAM5 View Gene Set 0.001305 13 0.02237 130 Protein-protein-interaction for PGAM5 www.ncbi.nlm.ni...
Null ppi.PSMD10 View Gene Set 0.001298 14 0.02237 130 Protein-protein-interaction for PSMD10 www.ncbi.nlm.ni...
Null ppi.THAP7 View Gene Set 0.001295 12 0.02237 130 Protein-protein-interaction for THAP7 www.ncbi.nlm.ni...
Null ppi.RANBP3 View Gene Set 0.001268 6 0.02237 130 Protein-protein-interaction for RANBP3 www.ncbi.nlm.ni...
Null ppi.KAT2B View Gene Set 0.001301 71 0.02237 130 Protein-protein-interaction for KAT2B www.ncbi.nlm.ni...
Null ppi.SNRPF View Gene Set 0.001342 6 0.02283 135 Protein-protein-interaction for SNRPF www.ncbi.nlm.ni...
Null ppi.PSMD7 View Gene Set 0.00137 12 0.02314 136 Protein-protein-interaction for PSMD7 www.ncbi.nlm.ni...
Null ppi.RBM8A View Gene Set 0.001386 7 0.02324 137 Protein-protein-interaction for RBM8A www.ncbi.nlm.ni...
Null ppi.POLR1A View Gene Set 0.001412 11 0.02343 138 Protein-protein-interaction for POLR1A www.ncbi.nlm.ni...
Null ppi.H2AFY View Gene Set 0.001418 12 0.02343 138 Protein-protein-interaction for H2AFY www.ncbi.nlm.ni...
Null ppi.EIF3B View Gene Set 0.001438 10 0.0236 140 Protein-protein-interaction for EIF3B www.ncbi.nlm.ni...
Null ppi.TAF15 View Gene Set 0.001493 12 0.02433 141 Protein-protein-interaction for TAF15 www.ncbi.nlm.ni...
Null ppi.MED29 View Gene Set 0.001613 37 0.02591 142 Protein-protein-interaction for MED29 www.ncbi.nlm.ni...
Null ppi.CPSF7 View Gene Set 0.001603 11 0.02591 142 Protein-protein-interaction for CPSF7 www.ncbi.nlm.ni...
Null ppi.MYSM1 View Gene Set 0.001643 13 0.02615 144 Protein-protein-interaction for MYSM1 www.ncbi.nlm.ni...
Null ppi.HIST2H2AC View Gene Set 0.001651 13 0.02615 144 Protein-protein-interaction for HIST2H2AC www.ncbi.nlm.ni...
Null ppi.BAZ1B View Gene Set 0.001665 30 0.02619 146 Protein-protein-interaction for BAZ1B www.ncbi.nlm.ni...
Null ppi.EP400 View Gene Set 0.001824 10 0.02831 147 Protein-protein-interaction for EP400 www.ncbi.nlm.ni...
Null ppi.DDA1 View Gene Set 0.001819 44 0.02831 147 Protein-protein-interaction for DDA1 www.ncbi.nlm.ni...
Null ppi.64015 View Gene Set 0.001863 6 0.02873 149 Protein-protein-interaction for 64015 www.ncbi.nlm.ni...
Null ppi.TOPBP1 View Gene Set 0.002001 14 0.02984 150 Protein-protein-interaction for TOPBP1 www.ncbi.nlm.ni...
Null ppi.HNRNPUL1 View Gene Set 0.001967 9 0.02984 150 Protein-protein-interaction for HNRNPUL1 www.ncbi.nlm.ni...
Null ppi.RNF126 View Gene Set 0.001953 7 0.02984 150 Protein-protein-interaction for RNF126 www.ncbi.nlm.ni...
Null ppi.PRKDC View Gene Set 0.001975 38 0.02984 150 Protein-protein-interaction for PRKDC www.ncbi.nlm.ni...
Null ppi.SNRPD3 View Gene Set 0.001988 7 0.02984 150 Protein-protein-interaction for SNRPD3 www.ncbi.nlm.ni...
Null ppi.TBL1XR1 View Gene Set 0.002033 9 0.03013 155 Protein-protein-interaction for TBL1XR1 www.ncbi.nlm.ni...
Null ppi.EIF3G View Gene Set 0.002048 8 0.03015 156 Protein-protein-interaction for EIF3G www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 0.002072 9 0.03031 157 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.MGMT View Gene Set 0.002109 28 0.03067 158 Protein-protein-interaction for MGMT www.ncbi.nlm.ni...
Null ppi.DPY30 View Gene Set 0.002138 9 0.03089 159 Protein-protein-interaction for DPY30 www.ncbi.nlm.ni...
Null ppi.C8orf41 View Gene Set 0.002185 10 0.03136 160 Protein-protein-interaction for C8orf41 www.ncbi.nlm.ni...
Null ppi.LYAR View Gene Set 0.0022 26 0.03139 161 Protein-protein-interaction for LYAR www.ncbi.nlm.ni...
Null ppi.KAT2A View Gene Set 0.002216 12 0.03143 162 Protein-protein-interaction for KAT2A www.ncbi.nlm.ni...
Null ppi.PAFAH1B3 View Gene Set 0.00228 10 0.03167 163 Protein-protein-interaction for PAFAH1B3 www.ncbi.nlm.ni...
Null ppi.SNRPE View Gene Set 0.002258 7 0.03167 163 Protein-protein-interaction for SNRPE www.ncbi.nlm.ni...
Null ppi.MYST1 View Gene Set 0.002289 14 0.03167 163 Protein-protein-interaction for MYST1 www.ncbi.nlm.ni...
Null ppi.EXO1 View Gene Set 0.002277 7 0.03167 163 Protein-protein-interaction for EXO1 www.ncbi.nlm.ni...
Null ppi.SRSF9 View Gene Set 0.002398 6 0.03299 167 Protein-protein-interaction for SRSF9 www.ncbi.nlm.ni...
Null ppi.PAAF1 View Gene Set 0.002413 20 0.03299 168 Protein-protein-interaction for PAAF1 www.ncbi.nlm.ni...
Null ppi.PRKAA1 View Gene Set 0.002436 6 0.03311 169 Protein-protein-interaction for PRKAA1 www.ncbi.nlm.ni...
Null ppi.TH1L View Gene Set 0.002473 26 0.03341 170 Protein-protein-interaction for TH1L www.ncbi.nlm.ni...
Null ppi.64196 View Gene Set 0.002573 6 0.03436 171 Protein-protein-interaction for 64196 www.ncbi.nlm.ni...
Null ppi.TRIM26 View Gene Set 0.002571 6 0.03436 171 Protein-protein-interaction for TRIM26 www.ncbi.nlm.ni...
Null ppi.POLR2J View Gene Set 0.002727 15 0.03613 173 Protein-protein-interaction for POLR2J www.ncbi.nlm.ni...
Null ppi.LSM10 View Gene Set 0.002737 9 0.03613 173 Protein-protein-interaction for LSM10 www.ncbi.nlm.ni...
Null ppi.XRN2 View Gene Set 0.002773 7 0.03617 175 Protein-protein-interaction for XRN2 www.ncbi.nlm.ni...
Null ppi.RAN View Gene Set 0.002787 8 0.03617 175 Protein-protein-interaction for RAN www.ncbi.nlm.ni...
Null ppi.NMI View Gene Set 0.00278 12 0.03617 175 Protein-protein-interaction for NMI www.ncbi.nlm.ni...
Null ppi.MED10 View Gene Set 0.002938 44 0.03791 178 Protein-protein-interaction for MED10 www.ncbi.nlm.ni...
Null ppi.PCBD1 View Gene Set 0.003037 6 0.03898 179 Protein-protein-interaction for PCBD1 www.ncbi.nlm.ni...
Null ppi.BCL7C View Gene Set 0.003065 11 0.03912 180 Protein-protein-interaction for BCL7C www.ncbi.nlm.ni...
Null ppi.ORC5L View Gene Set 0.003179 8 0.04034 181 Protein-protein-interaction for ORC5L www.ncbi.nlm.ni...
Null ppi.PPP4R2 View Gene Set 0.003277 7 0.04136 182 Protein-protein-interaction for PPP4R2 www.ncbi.nlm.ni...
Null ppi.ILF3 View Gene Set 0.003329 6 0.04178 183 Protein-protein-interaction for ILF3 www.ncbi.nlm.ni...
Null ppi.CD2BP2 View Gene Set 0.003431 13 0.04283 184 Protein-protein-interaction for CD2BP2 www.ncbi.nlm.ni...
Null ppi.C19orf40 View Gene Set 0.003456 6 0.04291 185 Protein-protein-interaction for C19orf40 www.ncbi.nlm.ni...
Null ppi.GTF3C3 View Gene Set 0.003537 11 0.04369 186 Protein-protein-interaction for GTF3C3 www.ncbi.nlm.ni...
Null ppi.RUVBL1 View Gene Set 0.003687 38 0.04528 187 Protein-protein-interaction for RUVBL1 www.ncbi.nlm.ni...
Null ppi.HIST3H3 View Gene Set 0.003726 16 0.04553 188 Protein-protein-interaction for HIST3H3 www.ncbi.nlm.ni...
Null ppi.HIST1H3A View Gene Set 0.003769 30 0.0458 189 Protein-protein-interaction for HIST1H3A www.ncbi.nlm.ni...
Null ppi.MED19 View Gene Set 0.003953 45 0.04779 190 Protein-protein-interaction for MED19 www.ncbi.nlm.ni...
Null ppi.RFC1 View Gene Set 0.003995 18 0.04804 191 Protein-protein-interaction for RFC1 www.ncbi.nlm.ni...
Null ppi.MLH1 View Gene Set 0.004097 9 0.04881 192 Protein-protein-interaction for MLH1 www.ncbi.nlm.ni...
Null ppi.SEH1L View Gene Set 0.004101 6 0.04881 192 Protein-protein-interaction for SEH1L www.ncbi.nlm.ni...
Null ppi.UHRF1 View Gene Set 0.004167 8 0.04934 194 Protein-protein-interaction for UHRF1 www.ncbi.nlm.ni...
Null ppi.MED9 View Gene Set 0.004206 31 0.04954 195 Protein-protein-interaction for MED9 www.ncbi.nlm.ni...
Null ppi.RAD51 View Gene Set 0.004231 12 0.04958 196 Protein-protein-interaction for RAD51 www.ncbi.nlm.ni...

Gene Set Collection: ppi.HPRD

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.SFRS12 View Gene Set 9.822e-16 49 2.332e-12 1 Protein-protein-interaction for SFRS12 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 6.65e-08 166 7.893e-05 2 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.SNIP1 View Gene Set 1.506e-06 27 0.001192 3 Protein-protein-interaction for SNIP1 www.ncbi.nlm.ni...
Null ppi.SUMO4 View Gene Set 3.299e-06 76 0.001958 4 Protein-protein-interaction for SUMO4 www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 7.102e-06 18 0.003372 5 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 1.253e-05 17 0.004958 6 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 4.662e-05 8 0.01383 7 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.NAA38 View Gene Set 4.13e-05 20 0.01383 7 Protein-protein-interaction for NAA38 www.ncbi.nlm.ni...
Null ppi.SMN2 View Gene Set 6.35e-05 9 0.01433 9 Protein-protein-interaction for SMN2 www.ncbi.nlm.ni...
Null ppi.SIP1 View Gene Set 6.642e-05 13 0.01433 9 Protein-protein-interaction for SIP1 www.ncbi.nlm.ni...
Null ppi.EIF2S2 View Gene Set 5.9e-05 17 0.01433 9 Protein-protein-interaction for EIF2S2 www.ncbi.nlm.ni...
Null ppi.RAN View Gene Set 9.384e-05 14 0.01714 12 Protein-protein-interaction for RAN www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 9.302e-05 13 0.01714 12 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.XRN1 View Gene Set 0.0001037 24 0.01759 14 Protein-protein-interaction for XRN1 www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 0.0001295 26 0.02049 15 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.NUP98 View Gene Set 0.0001687 8 0.02504 16 Protein-protein-interaction for NUP98 www.ncbi.nlm.ni...
Null ppi.GEMIN5 View Gene Set 0.0001876 10 0.0262 17 Protein-protein-interaction for GEMIN5 www.ncbi.nlm.ni...
Null ppi.NUP62 View Gene Set 0.0002067 19 0.02643 18 Protein-protein-interaction for NUP62 www.ncbi.nlm.ni...
Null ppi.PGR View Gene Set 0.0002115 9 0.02643 18 Protein-protein-interaction for PGR www.ncbi.nlm.ni...
Null ppi.LSM5 View Gene Set 0.0002827 6 0.02796 20 Protein-protein-interaction for LSM5 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 0.0002616 11 0.02796 20 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 0.0002757 10 0.02796 20 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.WDR77 View Gene Set 0.0002697 11 0.02796 20 Protein-protein-interaction for WDR77 www.ncbi.nlm.ni...
Null ppi.C4orf14 View Gene Set 0.0002743 12 0.02796 20 Protein-protein-interaction for C4orf14 www.ncbi.nlm.ni...
Null ppi.NCBP2 View Gene Set 0.0003624 6 0.03441 25 Protein-protein-interaction for NCBP2 www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 0.0003988 14 0.03641 26 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.UPF2 View Gene Set 0.000449 16 0.0387 27 Protein-protein-interaction for UPF2 www.ncbi.nlm.ni...
Null ppi.SRSF9 View Gene Set 0.0004564 7 0.0387 27 Protein-protein-interaction for SRSF9 www.ncbi.nlm.ni...
Null ppi.RPL5 View Gene Set 0.0004784 10 0.03916 29 Protein-protein-interaction for RPL5 www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 0.0005267 22 0.04033 30 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.GEMIN7 View Gene Set 0.0005154 9 0.04033 30 Protein-protein-interaction for GEMIN7 www.ncbi.nlm.ni...
Null ppi.RALYL View Gene Set 0.0005646 11 0.04189 32 Protein-protein-interaction for RALYL www.ncbi.nlm.ni...
Null ppi.EIF5 View Gene Set 0.000607 6 0.04367 33 Protein-protein-interaction for EIF5 www.ncbi.nlm.ni...
Null ppi.SRPK1 View Gene Set 0.0006264 12 0.04374 34 Protein-protein-interaction for SRPK1 www.ncbi.nlm.ni...
Null ppi.XPOT View Gene Set 0.0006825 6 0.04629 35 Protein-protein-interaction for XPOT www.ncbi.nlm.ni...
Null ppi.LSM3 View Gene Set 0.0007561 12 0.04929 36 Protein-protein-interaction for LSM3 www.ncbi.nlm.ni...
Null ppi.RBM8A View Gene Set 0.0007681 6 0.04929 36 Protein-protein-interaction for RBM8A www.ncbi.nlm.ni...

Gene Set Collection: ppi.anyDB

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null ppi.155871 View Gene Set 1.415e-36 251 5.085e-33 1 Protein-protein-interaction for 155871 www.ncbi.nlm.ni...
Null ppi.MEPCE View Gene Set 3.901e-21 147 7.011e-18 2 Protein-protein-interaction for MEPCE www.ncbi.nlm.ni...
Null ppi.SFRS12 View Gene Set 4.131e-16 50 4.949e-13 3 Protein-protein-interaction for SFRS12 www.ncbi.nlm.ni...
Null ppi.SRRM1 View Gene Set 5.006e-12 66 4.498e-09 4 Protein-protein-interaction for SRRM1 www.ncbi.nlm.ni...
Null ppi.SRRM2 View Gene Set 5.637e-10 101 4.052e-07 5 Protein-protein-interaction for SRRM2 www.ncbi.nlm.ni...
Null ppi.KHDRBS2 View Gene Set 1.225e-08 48 7.336e-06 6 Protein-protein-interaction for KHDRBS2 www.ncbi.nlm.ni...
Null ppi.72462 View Gene Set 4.202e-08 42 2.157e-05 7 Protein-protein-interaction for 72462 www.ncbi.nlm.ni...
Null ppi.GPN1 View Gene Set 8.089e-08 27 3.634e-05 8 Protein-protein-interaction for GPN1 www.ncbi.nlm.ni...
Null ppi.RPA1 View Gene Set 2.113e-07 24 7.337e-05 9 Protein-protein-interaction for RPA1 www.ncbi.nlm.ni...
Null ppi.RPA2 View Gene Set 2.654e-07 25 7.337e-05 9 Protein-protein-interaction for RPA2 www.ncbi.nlm.ni...
Null ppi.SSRP1 View Gene Set 2.585e-07 21 7.337e-05 9 Protein-protein-interaction for SSRP1 www.ncbi.nlm.ni...
Null ppi.CDT1 View Gene Set 1.912e-07 42 7.337e-05 9 Protein-protein-interaction for CDT1 www.ncbi.nlm.ni...
Null ppi.USP42 View Gene Set 2.591e-07 24 7.337e-05 9 Protein-protein-interaction for USP42 www.ncbi.nlm.ni...
Null ppi.TP53 View Gene Set 2.966e-07 220 7.615e-05 14 Protein-protein-interaction for TP53 www.ncbi.nlm.ni...
Null ppi.HIST1H4A View Gene Set 4.49e-07 31 0.0001076 15 Protein-protein-interaction for HIST1H4A www.ncbi.nlm.ni...
Null ppi.XRCC5 View Gene Set 7.404e-07 52 0.0001663 16 Protein-protein-interaction for XRCC5 www.ncbi.nlm.ni...
Null ppi.RRP1B View Gene Set 7.892e-07 21 0.0001668 17 Protein-protein-interaction for RRP1B www.ncbi.nlm.ni...
Null ppi.WBP4 View Gene Set 2.049e-06 35 0.0003876 18 Protein-protein-interaction for WBP4 www.ncbi.nlm.ni...
Null ppi.NAA38 View Gene Set 2.036e-06 28 0.0003876 18 Protein-protein-interaction for NAA38 www.ncbi.nlm.ni...
Null ppi.WRN View Gene Set 2.182e-06 21 0.000392 20 Protein-protein-interaction for WRN www.ncbi.nlm.ni...
Null ppi.EIF3F View Gene Set 2.503e-06 25 0.0004284 21 Protein-protein-interaction for EIF3F www.ncbi.nlm.ni...
Null ppi.GIGYF2 View Gene Set 2.667e-06 19 0.000429 22 Protein-protein-interaction for GIGYF2 www.ncbi.nlm.ni...
Null ppi.EXOSC5 View Gene Set 2.746e-06 20 0.000429 22 Protein-protein-interaction for EXOSC5 www.ncbi.nlm.ni...
Null ppi.SUMO4 View Gene Set 3.299e-06 76 0.0004428 24 Protein-protein-interaction for SUMO4 www.ncbi.nlm.ni...
Null ppi.PRPF40A View Gene Set 3.208e-06 96 0.0004428 24 Protein-protein-interaction for PRPF40A www.ncbi.nlm.ni...
Null ppi.SUMO2 View Gene Set 3.326e-06 55 0.0004428 24 Protein-protein-interaction for SUMO2 www.ncbi.nlm.ni...
Null ppi.SNIP1 View Gene Set 3.194e-06 28 0.0004428 24 Protein-protein-interaction for SNIP1 www.ncbi.nlm.ni...
Null ppi.RNU12-2P View Gene Set 3.851e-06 18 0.0004773 28 Protein-protein-interaction for RNU12-2P www.ncbi.nlm.ni...
Null ppi.RNU11 View Gene Set 3.851e-06 18 0.0004773 28 Protein-protein-interaction for RNU11 www.ncbi.nlm.ni...
Null ppi.UCHL5 View Gene Set 5.423e-06 34 0.0006497 30 Protein-protein-interaction for UCHL5 www.ncbi.nlm.ni...
Null ppi.RAD50 View Gene Set 5.748e-06 21 0.0006664 31 Protein-protein-interaction for RAD50 www.ncbi.nlm.ni...
Null ppi.PABPC1 View Gene Set 6.206e-06 37 0.000697 32 Protein-protein-interaction for PABPC1 www.ncbi.nlm.ni...
Null ppi.RNPS1 View Gene Set 6.445e-06 44 0.0007019 33 Protein-protein-interaction for RNPS1 www.ncbi.nlm.ni...
Null ppi.ORC2L View Gene Set 8.945e-06 15 0.0008894 34 Protein-protein-interaction for ORC2L www.ncbi.nlm.ni...
Null ppi.USP36 View Gene Set 8.643e-06 17 0.0008894 34 Protein-protein-interaction for USP36 www.ncbi.nlm.ni...
Null ppi.WDR77 View Gene Set 9.156e-06 18 0.0008894 34 Protein-protein-interaction for WDR77 www.ncbi.nlm.ni...
Null ppi.MED26 View Gene Set 9.139e-06 23 0.0008894 34 Protein-protein-interaction for MED26 www.ncbi.nlm.ni...
Null ppi.RUVBL2 View Gene Set 9.773e-06 72 0.0009243 38 Protein-protein-interaction for RUVBL2 www.ncbi.nlm.ni...
Null ppi.ORC6L View Gene Set 1.051e-05 15 0.000969 39 Protein-protein-interaction for ORC6L www.ncbi.nlm.ni...
Null ppi.RPAP2 View Gene Set 1.29e-05 43 0.001159 40 Protein-protein-interaction for RPAP2 www.ncbi.nlm.ni...
Null ppi.PSMD13 View Gene Set 1.614e-05 20 0.001415 41 Protein-protein-interaction for PSMD13 www.ncbi.nlm.ni...
Null ppi.EIF3H View Gene Set 2.746e-05 16 0.00235 42 Protein-protein-interaction for EIF3H www.ncbi.nlm.ni...
Null ppi.UPF2 View Gene Set 2.935e-05 19 0.002453 43 Protein-protein-interaction for UPF2 www.ncbi.nlm.ni...
Null ppi.GEMIN6 View Gene Set 3.323e-05 14 0.002714 44 Protein-protein-interaction for GEMIN6 www.ncbi.nlm.ni...
Null ppi.CBX5 View Gene Set 3.415e-05 46 0.002727 45 Protein-protein-interaction for CBX5 www.ncbi.nlm.ni...
Null ppi.TERF2 View Gene Set 3.757e-05 10 0.002936 46 Protein-protein-interaction for TERF2 www.ncbi.nlm.ni...
Null ppi.RAN View Gene Set 4.908e-05 15 0.003753 47 Protein-protein-interaction for RAN www.ncbi.nlm.ni...
Null ppi.TAF10 View Gene Set 5.034e-05 29 0.003769 48 Protein-protein-interaction for TAF10 www.ncbi.nlm.ni...
Null ppi.EIF2S2 View Gene Set 5.9e-05 17 0.004328 49 Protein-protein-interaction for EIF2S2 www.ncbi.nlm.ni...
Null ppi.NXF1 View Gene Set 6.41e-05 17 0.004517 50 Protein-protein-interaction for NXF1 www.ncbi.nlm.ni...
Null ppi.RPAP1 View Gene Set 6.396e-05 24 0.004517 50 Protein-protein-interaction for RPAP1 www.ncbi.nlm.ni...
Null ppi.PRMT5 View Gene Set 6.971e-05 35 0.004746 52 Protein-protein-interaction for PRMT5 www.ncbi.nlm.ni...
Null ppi.ORC3L View Gene Set 7.11e-05 16 0.004746 52 Protein-protein-interaction for ORC3L www.ncbi.nlm.ni...
Null ppi.HNRNPL View Gene Set 7.262e-05 9 0.004746 52 Protein-protein-interaction for HNRNPL www.ncbi.nlm.ni...
Null ppi.XRN1 View Gene Set 7.263e-05 25 0.004746 52 Protein-protein-interaction for XRN1 www.ncbi.nlm.ni...
Null ppi.SNUPN View Gene Set 7.872e-05 12 0.005052 56 Protein-protein-interaction for SNUPN www.ncbi.nlm.ni...
Null ppi.GIYD2 View Gene Set 8.391e-05 32 0.005291 57 Protein-protein-interaction for GIYD2 www.ncbi.nlm.ni...
Null ppi.SIP1 View Gene Set 8.785e-05 17 0.005444 58 Protein-protein-interaction for SIP1 www.ncbi.nlm.ni...
Null ppi.DBF4 View Gene Set 0.0001024 12 0.006036 59 Protein-protein-interaction for DBF4 www.ncbi.nlm.ni...
Null ppi.PDS5A View Gene Set 0.0001023 6 0.006036 59 Protein-protein-interaction for PDS5A www.ncbi.nlm.ni...
Null ppi.NUP62 View Gene Set 0.0001016 25 0.006036 59 Protein-protein-interaction for NUP62 www.ncbi.nlm.ni...
Null ppi.GEMIN5 View Gene Set 0.0001086 14 0.006298 62 Protein-protein-interaction for GEMIN5 www.ncbi.nlm.ni...
Null ppi.LSM2 View Gene Set 0.0001147 26 0.006443 63 Protein-protein-interaction for LSM2 www.ncbi.nlm.ni...
Null ppi.CHTF18 View Gene Set 0.0001144 13 0.006443 63 Protein-protein-interaction for CHTF18 www.ncbi.nlm.ni...
Null ppi.DDX20 View Gene Set 0.0001269 26 0.006944 65 Protein-protein-interaction for DDX20 www.ncbi.nlm.ni...
Null ppi.ZBTB9 View Gene Set 0.0001286 16 0.006944 65 Protein-protein-interaction for ZBTB9 www.ncbi.nlm.ni...
Null ppi.USP50 View Gene Set 0.0001294 22 0.006944 65 Protein-protein-interaction for USP50 www.ncbi.nlm.ni...
Null ppi.PSMD14 View Gene Set 0.0001654 16 0.008597 68 Protein-protein-interaction for PSMD14 www.ncbi.nlm.ni...
Null ppi.RALYL View Gene Set 0.0001674 12 0.008597 68 Protein-protein-interaction for RALYL www.ncbi.nlm.ni...
Null ppi.ORC1L View Gene Set 0.0001674 11 0.008597 68 Protein-protein-interaction for ORC1L www.ncbi.nlm.ni...
Null ppi.RNMTL1 View Gene Set 0.0001747 8 0.008602 71 Protein-protein-interaction for RNMTL1 www.ncbi.nlm.ni...
Null ppi.UPF3A View Gene Set 0.0001736 18 0.008602 71 Protein-protein-interaction for UPF3A www.ncbi.nlm.ni...
Null ppi.SNORD3A View Gene Set 0.0001729 9 0.008602 71 Protein-protein-interaction for SNORD3A www.ncbi.nlm.ni...
Null ppi.SMN2 View Gene Set 0.0001826 11 0.008869 74 Protein-protein-interaction for SMN2 www.ncbi.nlm.ni...
Null ppi.MCPH1 View Gene Set 0.0001958 17 0.009385 75 Protein-protein-interaction for MCPH1 www.ncbi.nlm.ni...
Null ppi.SAE1 View Gene Set 0.0002014 10 0.009526 76 Protein-protein-interaction for SAE1 www.ncbi.nlm.ni...
Null ppi.GAR1 View Gene Set 0.0002086 10 0.009735 77 Protein-protein-interaction for GAR1 www.ncbi.nlm.ni...
Null ppi.SMC1A View Gene Set 0.0002185 23 0.01007 78 Protein-protein-interaction for SMC1A www.ncbi.nlm.ni...
Null ppi.MSH2 View Gene Set 0.0002349 20 0.01068 79 Protein-protein-interaction for MSH2 www.ncbi.nlm.ni...
Null ppi.BANF1 View Gene Set 0.0002385 35 0.01072 80 Protein-protein-interaction for BANF1 www.ncbi.nlm.ni...
Null ppi.MCM6 View Gene Set 0.0002586 7 0.01147 81 Protein-protein-interaction for MCM6 www.ncbi.nlm.ni...
Null ppi.SUB1 View Gene Set 0.0002681 14 0.01171 82 Protein-protein-interaction for SUB1 www.ncbi.nlm.ni...
Null ppi.LSM5 View Gene Set 0.0002827 6 0.01171 82 Protein-protein-interaction for LSM5 www.ncbi.nlm.ni...
Null ppi.NUP43 View Gene Set 0.0002753 6 0.01171 82 Protein-protein-interaction for NUP43 www.ncbi.nlm.ni...
Null ppi.ING3 View Gene Set 0.0002779 12 0.01171 82 Protein-protein-interaction for ING3 www.ncbi.nlm.ni...
Null ppi.C4orf14 View Gene Set 0.0002743 12 0.01171 82 Protein-protein-interaction for C4orf14 www.ncbi.nlm.ni...
Null ppi.TTI1 View Gene Set 0.0002868 8 0.01171 82 Protein-protein-interaction for TTI1 www.ncbi.nlm.ni...
Null ppi.MED13 View Gene Set 0.0002854 12 0.01171 82 Protein-protein-interaction for MED13 www.ncbi.nlm.ni...
Null ppi.PMS2 View Gene Set 0.0003064 14 0.01225 89 Protein-protein-interaction for PMS2 www.ncbi.nlm.ni...
Null ppi.MED23 View Gene Set 0.0003067 15 0.01225 89 Protein-protein-interaction for MED23 www.ncbi.nlm.ni...
Null ppi.COPS4 View Gene Set 0.0003126 17 0.01228 91 Protein-protein-interaction for COPS4 www.ncbi.nlm.ni...
Null ppi.SF3A2 View Gene Set 0.0003143 16 0.01228 91 Protein-protein-interaction for SF3A2 www.ncbi.nlm.ni...
Null ppi.WDR48 View Gene Set 0.0003209 52 0.0124 93 Protein-protein-interaction for WDR48 www.ncbi.nlm.ni...
Null ppi.ORC5L View Gene Set 0.0003248 11 0.01242 94 Protein-protein-interaction for ORC5L www.ncbi.nlm.ni...
Null ppi.POLR3H View Gene Set 0.0003409 15 0.0129 95 Protein-protein-interaction for POLR3H www.ncbi.nlm.ni...
Null ppi.TAF1D View Gene Set 0.0003574 21 0.01338 96 Protein-protein-interaction for TAF1D www.ncbi.nlm.ni...
Null ppi.NCBP2 View Gene Set 0.0003624 6 0.01343 97 Protein-protein-interaction for NCBP2 www.ncbi.nlm.ni...
Null ppi.SIN3A View Gene Set 0.0003903 116 0.01432 98 Protein-protein-interaction for SIN3A www.ncbi.nlm.ni...
Null ppi.COPS8 View Gene Set 0.0004173 13 0.015 99 Protein-protein-interaction for COPS8 www.ncbi.nlm.ni...
Null ppi.H2AFY View Gene Set 0.0004155 13 0.015 99 Protein-protein-interaction for H2AFY www.ncbi.nlm.ni...
Null ppi.MRE11A View Gene Set 0.000426 16 0.01516 101 Protein-protein-interaction for MRE11A www.ncbi.nlm.ni...
Null ppi.MED24 View Gene Set 0.0004354 20 0.01534 102 Protein-protein-interaction for MED24 www.ncbi.nlm.ni...
Null ppi.ATRIP View Gene Set 0.0004421 13 0.01543 103 Protein-protein-interaction for ATRIP www.ncbi.nlm.ni...
Null ppi.LSM3 View Gene Set 0.0004537 13 0.01565 104 Protein-protein-interaction for LSM3 www.ncbi.nlm.ni...
Null ppi.PRMT1 View Gene Set 0.0004572 17 0.01565 104 Protein-protein-interaction for PRMT1 www.ncbi.nlm.ni...
Null ppi.SUPT16H View Gene Set 0.0004635 15 0.01571 106 Protein-protein-interaction for SUPT16H www.ncbi.nlm.ni...
Null ppi.USP39 View Gene Set 0.0004774 16 0.01589 107 Protein-protein-interaction for USP39 www.ncbi.nlm.ni...
Null ppi.ZNF496 View Gene Set 0.0004735 13 0.01589 107 Protein-protein-interaction for ZNF496 www.ncbi.nlm.ni...
Null ppi.NUTF2 View Gene Set 0.0005071 5 0.0164 109 Protein-protein-interaction for NUTF2 www.ncbi.nlm.ni...
Null ppi.SRPK2 View Gene Set 0.0005033 7 0.0164 109 Protein-protein-interaction for SRPK2 www.ncbi.nlm.ni...
Null ppi.XPA View Gene Set 0.0005158 14 0.0164 109 Protein-protein-interaction for XPA www.ncbi.nlm.ni...
Null ppi.GEMIN7 View Gene Set 0.0005154 10 0.0164 109 Protein-protein-interaction for GEMIN7 www.ncbi.nlm.ni...
Null ppi.ZRANB2 View Gene Set 0.0005027 11 0.0164 109 Protein-protein-interaction for ZRANB2 www.ncbi.nlm.ni...
Null ppi.KEAP1 View Gene Set 0.000526 22 0.01658 114 Protein-protein-interaction for KEAP1 www.ncbi.nlm.ni...
Null ppi.CDC20 View Gene Set 0.0005499 5 0.01718 115 Protein-protein-interaction for CDC20 www.ncbi.nlm.ni...
Null ppi.XPOT View Gene Set 0.0005925 9 0.01788 116 Protein-protein-interaction for XPOT www.ncbi.nlm.ni...
Null ppi.EIF5 View Gene Set 0.000607 6 0.01788 116 Protein-protein-interaction for EIF5 www.ncbi.nlm.ni...
Null ppi.DMAP1 View Gene Set 0.0005827 16 0.01788 116 Protein-protein-interaction for DMAP1 www.ncbi.nlm.ni...
Null ppi.RANGAP1 View Gene Set 0.0005881 5 0.01788 116 Protein-protein-interaction for RANGAP1 www.ncbi.nlm.ni...
Null ppi.DSCC1 View Gene Set 0.0005869 6 0.01788 116 Protein-protein-interaction for DSCC1 www.ncbi.nlm.ni...
Null ppi.SRSF9 View Gene Set 0.0006051 8 0.01788 116 Protein-protein-interaction for SRSF9 www.ncbi.nlm.ni...
Null ppi.USP14 View Gene Set 0.0006064 22 0.01788 116 Protein-protein-interaction for USP14 www.ncbi.nlm.ni...
Null ppi.SRPK1 View Gene Set 0.0006264 12 0.0183 123 Protein-protein-interaction for SRPK1 www.ncbi.nlm.ni...
Null ppi.MDC1 View Gene Set 0.0006332 24 0.01835 124 Protein-protein-interaction for MDC1 www.ncbi.nlm.ni...
Null ppi.RPAP3 View Gene Set 0.0006551 30 0.01879 125 Protein-protein-interaction for RPAP3 www.ncbi.nlm.ni...
Null ppi.HIST2H2AC View Gene Set 0.0006587 14 0.01879 125 Protein-protein-interaction for HIST2H2AC www.ncbi.nlm.ni...
Null ppi.CD2BP2 View Gene Set 0.0006739 15 0.01907 127 Protein-protein-interaction for CD2BP2 www.ncbi.nlm.ni...
Null ppi.HNRNPUL1 View Gene Set 0.0006899 11 0.01916 128 Protein-protein-interaction for HNRNPUL1 www.ncbi.nlm.ni...
Null ppi.155348 View Gene Set 0.0006989 9 0.01916 128 Protein-protein-interaction for 155348 www.ncbi.nlm.ni...
Null ppi.KAT2A View Gene Set 0.0007091 14 0.01916 128 Protein-protein-interaction for KAT2A www.ncbi.nlm.ni...
Null ppi.PGR View Gene Set 0.0007084 15 0.01916 128 Protein-protein-interaction for PGR www.ncbi.nlm.ni...
Null ppi.EIF2B5 View Gene Set 0.0007052 10 0.01916 128 Protein-protein-interaction for EIF2B5 www.ncbi.nlm.ni...
Null ppi.EXO1 View Gene Set 0.0007045 8 0.01916 128 Protein-protein-interaction for EXO1 www.ncbi.nlm.ni...
Null ppi.EP400 View Gene Set 0.0007238 11 0.01941 134 Protein-protein-interaction for EP400 www.ncbi.nlm.ni...
Null ppi.OTUB1 View Gene Set 0.0007355 19 0.01944 135 Protein-protein-interaction for OTUB1 www.ncbi.nlm.ni...
Null ppi.PSMD7 View Gene Set 0.0007339 13 0.01944 135 Protein-protein-interaction for PSMD7 www.ncbi.nlm.ni...
Null ppi.PSMD10 View Gene Set 0.0007554 16 0.01982 137 Protein-protein-interaction for PSMD10 www.ncbi.nlm.ni...
Null ppi.RBM8A View Gene Set 0.0007655 8 0.01994 138 Protein-protein-interaction for RBM8A www.ncbi.nlm.ni...
Null ppi.POLR1C View Gene Set 0.0007812 7 0.0202 139 Protein-protein-interaction for POLR1C www.ncbi.nlm.ni...
Null ppi.TOPORS View Gene Set 0.000806 28 0.02054 140 Protein-protein-interaction for TOPORS www.ncbi.nlm.ni...
Null ppi.CHEK2 View Gene Set 0.0008042 33 0.02054 140 Protein-protein-interaction for CHEK2 www.ncbi.nlm.ni...
Null ppi.SMAD6 View Gene Set 0.0008218 8 0.0208 142 Protein-protein-interaction for SMAD6 www.ncbi.nlm.ni...
Null ppi.SYNCRIP View Gene Set 0.000837 22 0.02104 143 Protein-protein-interaction for SYNCRIP www.ncbi.nlm.ni...
Null ppi.POLR3C View Gene Set 0.0008601 10 0.02147 144 Protein-protein-interaction for POLR3C www.ncbi.nlm.ni...
Null ppi.TH1L View Gene Set 0.0008735 29 0.02151 145 Protein-protein-interaction for TH1L www.ncbi.nlm.ni...
Null ppi.NOL12 View Gene Set 0.0008738 7 0.02151 145 Protein-protein-interaction for NOL12 www.ncbi.nlm.ni...
Null ppi.MED29 View Gene Set 0.0009119 38 0.0223 147 Protein-protein-interaction for MED29 www.ncbi.nlm.ni...
Null ppi.BRF2 View Gene Set 0.0009252 25 0.02247 148 Protein-protein-interaction for BRF2 www.ncbi.nlm.ni...
Null ppi.MYC View Gene Set 0.000987 56 0.02365 149 Protein-protein-interaction for MYC www.ncbi.nlm.ni...
Null ppi.MED10 View Gene Set 0.000985 46 0.02365 149 Protein-protein-interaction for MED10 www.ncbi.nlm.ni...
Null ppi.UPF1 View Gene Set 0.0009958 8 0.0237 151 Protein-protein-interaction for UPF1 www.ncbi.nlm.ni...
Null ppi.ILF3 View Gene Set 0.001005 7 0.02377 152 Protein-protein-interaction for ILF3 www.ncbi.nlm.ni...
Null ppi.OSBPL10 View Gene Set 0.001094 15 0.0257 153 Protein-protein-interaction for OSBPL10 www.ncbi.nlm.ni...
Null ppi.MCM10 View Gene Set 0.001102 28 0.02572 154 Protein-protein-interaction for MCM10 www.ncbi.nlm.ni...
Null ppi.POLR1A View Gene Set 0.001128 13 0.02616 155 Protein-protein-interaction for POLR1A www.ncbi.nlm.ni...
Null ppi.PDHX View Gene Set 0.001138 7 0.02616 155 Protein-protein-interaction for PDHX www.ncbi.nlm.ni...
Null ppi.NUP153 View Gene Set 0.001143 16 0.02616 155 Protein-protein-interaction for NUP153 www.ncbi.nlm.ni...
Null ppi.XPO1 View Gene Set 0.001155 43 0.02628 158 Protein-protein-interaction for XPO1 www.ncbi.nlm.ni...
Null ppi.BRCC3 View Gene Set 0.001212 22 0.02739 159 Protein-protein-interaction for BRCC3 www.ncbi.nlm.ni...
Null ppi.CDC45 View Gene Set 0.001219 13 0.02739 159 Protein-protein-interaction for CDC45 www.ncbi.nlm.ni...
Null ppi.HNRNPH1 View Gene Set 0.001247 9 0.02777 161 Protein-protein-interaction for HNRNPH1 www.ncbi.nlm.ni...
Null ppi.PRKDC View Gene Set 0.001252 49 0.02777 161 Protein-protein-interaction for PRKDC www.ncbi.nlm.ni...
Null ppi.RANBP3 View Gene Set 0.001268 6 0.02796 163 Protein-protein-interaction for RANBP3 www.ncbi.nlm.ni...
Null ppi.THAP7 View Gene Set 0.001295 12 0.02839 164 Protein-protein-interaction for THAP7 www.ncbi.nlm.ni...
Null ppi.SNRPF View Gene Set 0.001342 6 0.02923 165 Protein-protein-interaction for SNRPF www.ncbi.nlm.ni...
Null ppi.TBL1XR1 View Gene Set 0.001361 12 0.02947 166 Protein-protein-interaction for TBL1XR1 www.ncbi.nlm.ni...
Null ppi.PPARGC1A View Gene Set 0.001433 39 0.03084 167 Protein-protein-interaction for PPARGC1A www.ncbi.nlm.ni...
Null ppi.PSMD6 View Gene Set 0.001468 23 0.0314 168 Protein-protein-interaction for PSMD6 www.ncbi.nlm.ni...
Null ppi.CDK12 View Gene Set 0.001491 8 0.0317 169 Protein-protein-interaction for CDK12 www.ncbi.nlm.ni...
Null ppi.EXOSC6 View Gene Set 0.001503 31 0.03173 170 Protein-protein-interaction for EXOSC6 www.ncbi.nlm.ni...
Null ppi.UHRF1 View Gene Set 0.001519 12 0.03173 170 Protein-protein-interaction for UHRF1 www.ncbi.nlm.ni...
Null ppi.NBN View Gene Set 0.001515 16 0.03173 170 Protein-protein-interaction for NBN www.ncbi.nlm.ni...
Null ppi.NUP98 View Gene Set 0.001532 12 0.03182 173 Protein-protein-interaction for NUP98 www.ncbi.nlm.ni...
Null ppi.WWOX View Gene Set 0.001567 26 0.03237 174 Protein-protein-interaction for WWOX www.ncbi.nlm.ni...
Null ppi.RNF126 View Gene Set 0.00158 8 0.03244 175 Protein-protein-interaction for RNF126 www.ncbi.nlm.ni...
Null ppi.MYSM1 View Gene Set 0.001643 13 0.03326 176 Protein-protein-interaction for MYSM1 www.ncbi.nlm.ni...
Null ppi.RPL5 View Gene Set 0.001635 11 0.03326 176 Protein-protein-interaction for RPL5 www.ncbi.nlm.ni...
Null ppi.AURKA View Gene Set 0.001652 16 0.03326 176 Protein-protein-interaction for AURKA www.ncbi.nlm.ni...
Null ppi.GTF3C3 View Gene Set 0.001657 12 0.03326 176 Protein-protein-interaction for GTF3C3 www.ncbi.nlm.ni...
Null ppi.SNRPD1 View Gene Set 0.00167 6 0.03334 180 Protein-protein-interaction for SNRPD1 www.ncbi.nlm.ni...
Null ppi.DNTTIP2 View Gene Set 0.001741 7 0.03457 181 Protein-protein-interaction for DNTTIP2 www.ncbi.nlm.ni...
Null ppi.CPSF7 View Gene Set 0.001779 13 0.03512 182 Protein-protein-interaction for CPSF7 www.ncbi.nlm.ni...
Null ppi.MCM5 View Gene Set 0.001792 7 0.03518 183 Protein-protein-interaction for MCM5 www.ncbi.nlm.ni...
Null ppi.DDA1 View Gene Set 0.001819 44 0.03554 184 Protein-protein-interaction for DDA1 www.ncbi.nlm.ni...
Null ppi.64015 View Gene Set 0.001863 6 0.0362 185 Protein-protein-interaction for 64015 www.ncbi.nlm.ni...
Null ppi.ELP3 View Gene Set 0.001932 9 0.03734 186 Protein-protein-interaction for ELP3 www.ncbi.nlm.ni...
Null ppi.THOC4 View Gene Set 0.001994 5 0.03813 187 Protein-protein-interaction for THOC4 www.ncbi.nlm.ni...
Null ppi.SNRPD3 View Gene Set 0.001988 7 0.03813 187 Protein-protein-interaction for SNRPD3 www.ncbi.nlm.ni...
Null ppi.EIF3G View Gene Set 0.002048 8 0.03894 189 Protein-protein-interaction for EIF3G www.ncbi.nlm.ni...
Null ppi.PCNA View Gene Set 0.002075 47 0.03925 190 Protein-protein-interaction for PCNA www.ncbi.nlm.ni...
Null ppi.MCM2 View Gene Set 0.002091 13 0.03934 191 Protein-protein-interaction for MCM2 www.ncbi.nlm.ni...
Null ppi.MGMT View Gene Set 0.002109 28 0.03949 192 Protein-protein-interaction for MGMT www.ncbi.nlm.ni...
Null ppi.EXOSC4 View Gene Set 0.002136 21 0.03977 193 Protein-protein-interaction for EXOSC4 www.ncbi.nlm.ni...
Null ppi.C8orf41 View Gene Set 0.002185 10 0.04047 194 Protein-protein-interaction for C8orf41 www.ncbi.nlm.ni...
Null ppi.LYAR View Gene Set 0.0022 26 0.04055 195 Protein-protein-interaction for LYAR www.ncbi.nlm.ni...
Null ppi.SNRPE View Gene Set 0.002258 7 0.0414 196 Protein-protein-interaction for SNRPE www.ncbi.nlm.ni...
Null ppi.PAFAH1B3 View Gene Set 0.00228 10 0.04155 197 Protein-protein-interaction for PAFAH1B3 www.ncbi.nlm.ni...
Null ppi.MYST1 View Gene Set 0.002289 14 0.04155 197 Protein-protein-interaction for MYST1 www.ncbi.nlm.ni...
Null ppi.TIMM44 View Gene Set 0.002331 5 0.04189 199 Protein-protein-interaction for TIMM44 www.ncbi.nlm.ni...
Null ppi.SRSF2 View Gene Set 0.002324 6 0.04189 199 Protein-protein-interaction for SRSF2 www.ncbi.nlm.ni...

Gene Set Collection: pathwayCommons.cell-map

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null TNF alpha/NF-kB View Gene Set 0.001605 170 0.01605 1 CELL_MAP - TNF alpha/NF-kB gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.humancyc

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null purine nucleotides de novo biosynthesis II View Gene Set 0.0001184 11 0.03078 1 HUMANCYC - purine nucleotides de novo biosynthesis II gene set www.pathwaycomm...
Null folate polyglutamylation View Gene Set 0.0002534 5 0.03294 2 HUMANCYC - folate polyglutamylation gene set www.pathwaycomm...
Null folate transformations View Gene Set 0.0005929 9 0.03854 3 HUMANCYC - folate transformations gene set www.pathwaycomm...
Null pyrimidine ribonucleotides de novo biosynthesis View Gene Set 0.000538 11 0.03854 3 HUMANCYC - pyrimidine ribonucleotides de novo biosynthesis gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.nci-nature

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Validated targets of C-MYC transcriptional activation View Gene Set 5.739e-13 80 1.067e-10 1 NCI_NATURE - Validated targets of C-MYC transcriptional activation gene set www.pathwaycomm...
Null C-MYC pathway View Gene Set 1.152e-08 149 1.071e-06 2 NCI_NATURE - C-MYC pathway gene set www.pathwaycomm...
Null Signaling events mediated by HDAC Class I View Gene Set 3.05e-05 114 0.001891 3 NCI_NATURE - Signaling events mediated by HDAC Class I gene set www.pathwaycomm...
Null Regulation of Telomerase View Gene Set 0.0008584 68 0.03992 4 NCI_NATURE - Regulation of Telomerase gene set www.pathwaycomm...

Gene Set Collection: pathwayCommons.reactome

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Gene Expression View Gene Set 2.219e-39 381 2.478e-36 1 REACTOME - Gene Expression gene set www.pathwaycomm...
Null Processing of Capped Intron-Containing Pre-mRNA View Gene Set 7.894e-34 138 4.409e-31 2 REACTOME - Processing of Capped Intron-Containing Pre-mRNA gene set www.pathwaycomm...
Null mRNA Processing View Gene Set 4.443e-30 158 1.654e-27 3 REACTOME - mRNA Processing gene set www.pathwaycomm...
Null Formation and Maturation of mRNA Transcript View Gene Set 9.836e-29 185 2.747e-26 4 REACTOME - Formation and Maturation of mRNA Transcript gene set www.pathwaycomm...
Null mRNA Splicing - Major Pathway View Gene Set 6.18e-26 107 1.151e-23 5 REACTOME - mRNA Splicing - Major Pathway gene set www.pathwaycomm...
Null mRNA Splicing View Gene Set 6.18e-26 107 1.151e-23 5 REACTOME - mRNA Splicing gene set www.pathwaycomm...
Null Metabolism of RNA View Gene Set 6.744e-22 174 1.076e-19 7 REACTOME - Metabolism of RNA gene set www.pathwaycomm...
Null DNA Replication View Gene Set 9.04e-20 200 1.262e-17 8 REACTOME - DNA Replication gene set www.pathwaycomm...
Null Mitotic M-M/G1 phases View Gene Set 3.716e-19 180 4.612e-17 9 REACTOME - Mitotic M-M/G1 phases gene set www.pathwaycomm...
Null Cell Cycle Mitotic View Gene Set 2.41e-18 312 2.692e-16 10 REACTOME - Cell Cycle Mitotic gene set www.pathwaycomm... Mitotic&format=...
Null Transport of Mature Transcript to Cytoplasm View Gene Set 1.51e-17 55 1.533e-15 11 REACTOME - Transport of Mature Transcript to Cytoplasm gene set www.pathwaycomm...
Null Transport of Mature mRNA derived from an Intron-Containing Transcript View Gene Set 7.94e-17 51 7.391e-15 12 REACTOME - Transport of Mature mRNA derived from an Intron-Containing Transcript gene set www.pathwaycomm...
Null Transcription View Gene Set 3.485e-16 178 2.839e-14 13 REACTOME - Transcription gene set www.pathwaycomm...
Null snRNP Assembly View Gene Set 3.812e-16 50 2.839e-14 13 REACTOME - snRNP Assembly gene set www.pathwaycomm...
Null Metabolism of non-coding RNA View Gene Set 3.812e-16 50 2.839e-14 13 REACTOME - Metabolism of non-coding RNA gene set www.pathwaycomm...
Null tRNA Aminoacylation View Gene Set 1.634e-13 42 1.141e-11 16 REACTOME - tRNA Aminoacylation gene set www.pathwaycomm...
Null Post-Elongation Processing of the Transcript View Gene Set 1.092e-12 43 6.417e-11 17 REACTOME - Post-Elongation Processing of the Transcript gene set www.pathwaycomm...
Null Cleavage of Growing Transcript in the Termination Region View Gene Set 1.092e-12 43 6.417e-11 17 REACTOME - Cleavage of Growing Transcript in the Termination Region gene set www.pathwaycomm...
Null RNA Polymerase II Transcription Termination View Gene Set 1.092e-12 43 6.417e-11 17 REACTOME - RNA Polymerase II Transcription Termination gene set www.pathwaycomm...
Null Cell Cycle Checkpoints View Gene Set 1.485e-12 124 8.291e-11 20 REACTOME - Cell Cycle Checkpoints gene set www.pathwaycomm...
Null Interactions of Rev with host cellular proteins View Gene Set 6.027e-12 33 3.206e-10 21 REACTOME - Interactions of Rev with host cellular proteins gene set www.pathwaycomm...
Null Post-Elongation Processing of Intron-Containing pre-mRNA View Gene Set 8.793e-12 34 4.27e-10 22 REACTOME - Post-Elongation Processing of Intron-Containing pre-mRNA gene set www.pathwaycomm...
Null mRNA 3'-end processing View Gene Set 8.793e-12 34 4.27e-10 22 REACTOME - mRNA 3'-end processing gene set www.pathwaycomm...
Null Rev-mediated nuclear export of HIV-1 RNA View Gene Set 1.459e-11 32 6.791e-10 24 REACTOME - Rev-mediated nuclear export of HIV-1 RNA gene set www.pathwaycomm...
Null M Phase View Gene Set 3.981e-11 90 1.779e-09 25 REACTOME - M Phase gene set www.pathwaycomm...
Null Mitotic Prometaphase View Gene Set 4.19e-11 86 1.8e-09 26 REACTOME - Mitotic Prometaphase gene set www.pathwaycomm...
Null Transport of Mature mRNAs Derived from Intronless Transcripts View Gene Set 4.473e-11 36 1.851e-09 27 REACTOME - Transport of Mature mRNAs Derived from Intronless Transcripts gene set www.pathwaycomm...
Null Transport of Mature mRNA Derived from an Intronless Transcript View Gene Set 5.276e-11 35 2.105e-09 28 REACTOME - Transport of Mature mRNA Derived from an Intronless Transcript gene set www.pathwaycomm...
Null Nuclear import of Rev protein View Gene Set 1.861e-10 30 7.169e-09 29 REACTOME - Nuclear import of Rev protein gene set www.pathwaycomm...
Null Transport of the SLBP Dependant Mature mRNA View Gene Set 2.105e-10 33 7.838e-09 30 REACTOME - Transport of the SLBP Dependant Mature mRNA gene set www.pathwaycomm...
Null HIV Infection View Gene Set 2.221e-10 194 8.004e-09 31 REACTOME - HIV Infection gene set www.pathwaycomm...
Null Transport of the SLBP independent Mature mRNA View Gene Set 2.472e-10 32 8.629e-09 32 REACTOME - Transport of the SLBP independent Mature mRNA gene set www.pathwaycomm...
Null Metabolism of mRNA View Gene Set 2.637e-10 125 8.924e-09 33 REACTOME - Metabolism of mRNA gene set www.pathwaycomm...
Null RNA Polymerase II Transcription View Gene Set 2.838e-10 101 9.16e-09 34 REACTOME - RNA Polymerase II Transcription gene set www.pathwaycomm...
Null Export of Viral Ribonucleoproteins from Nucleus View Gene Set 2.87e-10 31 9.16e-09 34 REACTOME - Export of Viral Ribonucleoproteins from Nucleus gene set www.pathwaycomm...
Null NEP/NS2 Interacts with the Cellular Export Machinery View Gene Set 4.821e-10 29 1.496e-08 36 REACTOME - NEP/NS2 Interacts with the Cellular Export Machinery gene set www.pathwaycomm...
Null HIV Life Cycle View Gene Set 7.122e-10 103 2.15e-08 37 REACTOME - HIV Life Cycle gene set www.pathwaycomm...
Null Synthesis of DNA View Gene Set 7.47e-10 102 2.196e-08 38 REACTOME - Synthesis of DNA gene set www.pathwaycomm...
Null DNA Replication Pre-Initiation View Gene Set 8.852e-10 90 2.472e-08 39 REACTOME - DNA Replication Pre-Initiation gene set www.pathwaycomm...
Null M/G1 Transition View Gene Set 8.852e-10 90 2.472e-08 39 REACTOME - M/G1 Transition gene set www.pathwaycomm...
Null S Phase View Gene Set 2.067e-09 113 5.632e-08 41 REACTOME - S Phase gene set www.pathwaycomm...
Null Regulation of APC/C activators between G1/S and early anaphase View Gene Set 2.502e-09 88 6.655e-08 42 REACTOME - Regulation of APC/C activators between G1/S and early anaphase gene set www.pathwaycomm...
Null Vpr-mediated nuclear import of PICs View Gene Set 2.694e-09 31 6.838e-08 43 REACTOME - Vpr-mediated nuclear import of PICs gene set www.pathwaycomm...
Null Cytosolic tRNA aminoacylation View Gene Set 2.686e-09 24 6.838e-08 43 REACTOME - Cytosolic tRNA aminoacylation gene set www.pathwaycomm...
Null Late Phase of HIV Life Cycle View Gene Set 3.966e-09 92 9.843e-08 45 REACTOME - Late Phase of HIV Life Cycle gene set www.pathwaycomm...
Null Interactions of Vpr with host cellular proteins View Gene Set 5.148e-09 34 1.25e-07 46 REACTOME - Interactions of Vpr with host cellular proteins gene set www.pathwaycomm...
Null APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 View Gene Set 6.413e-09 77 1.524e-07 47 REACTOME - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 gene set www.pathwaycomm...
Null Assembly of the pre-replicative complex View Gene Set 7.855e-09 75 1.755e-07 48 REACTOME - Assembly of the pre-replicative complex gene set www.pathwaycomm...
Null Regulation of mitotic cell cycle View Gene Set 7.761e-09 95 1.755e-07 48 REACTOME - Regulation of mitotic cell cycle gene set www.pathwaycomm...
Null APC/C-mediated degradation of cell cycle proteins View Gene Set 7.761e-09 95 1.755e-07 48 REACTOME - APC/C-mediated degradation of cell cycle proteins gene set www.pathwaycomm...
Null Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 8.861e-09 86 1.941e-07 51 REACTOME - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null Host Interactions of HIV factors View Gene Set 9.393e-09 132 2.018e-07 52 REACTOME - Host Interactions of HIV factors gene set www.pathwaycomm...
Null Chromosome Maintenance View Gene Set 9.589e-09 69 2.021e-07 53 REACTOME - Chromosome Maintenance gene set www.pathwaycomm...
Null Transport of Ribonucleoproteins into the Host Nucleus View Gene Set 1.426e-08 29 2.95e-07 54 REACTOME - Transport of Ribonucleoproteins into the Host Nucleus gene set www.pathwaycomm...
Null mRNA Splicing - Minor Pathway View Gene Set 1.497e-08 42 3.04e-07 55 REACTOME - mRNA Splicing - Minor Pathway gene set www.pathwaycomm...
Null Regulation of Glucokinase by Glucokinase Regulatory Protein View Gene Set 4.42e-08 29 8.816e-07 56 REACTOME - Regulation of Glucokinase by Glucokinase Regulatory Protein gene set www.pathwaycomm...
Null Telomere Maintenance View Gene Set 5.222e-08 49 1.023e-06 57 REACTOME - Telomere Maintenance gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of Securin View Gene Set 6.031e-08 72 1.162e-06 58 REACTOME - APC/C:Cdc20 mediated degradation of Securin gene set www.pathwaycomm...
Null p53-Independent G1/S DNA damage checkpoint View Gene Set 1.018e-07 62 1.866e-06 59 REACTOME - p53-Independent G1/S DNA damage checkpoint gene set www.pathwaycomm...
Null p53-Independent DNA Damage Response View Gene Set 1.018e-07 62 1.866e-06 59 REACTOME - p53-Independent DNA Damage Response gene set www.pathwaycomm...
Null Cdc20:Phospho-APC/C mediated degradation of Cyclin A View Gene Set 1.019e-07 75 1.866e-06 59 REACTOME - Cdc20:Phospho-APC/C mediated degradation of Cyclin A gene set www.pathwaycomm...
Null Ubiquitin Mediated Degradation of Phosphorylated Cdc25A View Gene Set 1.362e-07 61 2.409e-06 62 REACTOME - Ubiquitin Mediated Degradation of Phosphorylated Cdc25A gene set www.pathwaycomm...
Null Glucose transport View Gene Set 1.402e-07 38 2.409e-06 62 REACTOME - Glucose transport gene set www.pathwaycomm...
Null APC/C:Cdc20 mediated degradation of mitotic proteins View Gene Set 1.393e-07 77 2.409e-06 62 REACTOME - APC/C:Cdc20 mediated degradation of mitotic proteins gene set www.pathwaycomm...
Null Destabilization of mRNA by AUF1 (hnRNP D0) View Gene Set 1.339e-07 63 2.409e-06 62 REACTOME - Destabilization of mRNA by AUF1 (hnRNP D0) gene set www.pathwaycomm...
Null Regulation of mRNA Stability by Proteins that Bind AU-rich Elements View Gene Set 1.464e-07 95 2.477e-06 66 REACTOME - Regulation of mRNA Stability by Proteins that Bind AU-rich Elements gene set www.pathwaycomm...
Null Meiotic Recombination View Gene Set 1.791e-07 42 2.985e-06 67 REACTOME - Meiotic Recombination gene set www.pathwaycomm...
Null SCF-beta-TrCP mediated degradation of Emi1 View Gene Set 1.854e-07 60 3.046e-06 68 REACTOME - SCF-beta-TrCP mediated degradation of Emi1 gene set www.pathwaycomm...
Null RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription View Gene Set 2.26e-07 93 3.658e-06 69 REACTOME - RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription gene set www.pathwaycomm... RNA Polymerase ... and Mitochondri...
Null Regulation of DNA replication View Gene Set 2.363e-07 81 3.771e-06 70 REACTOME - Regulation of DNA replication gene set www.pathwaycomm...
Null Deadenylation-dependent mRNA decay View Gene Set 2.834e-07 46 4.458e-06 71 REACTOME - Deadenylation-dependent mRNA decay gene set www.pathwaycomm...
Null Hexose transport View Gene Set 3.045e-07 40 4.659e-06 72 REACTOME - Hexose transport gene set www.pathwaycomm...
Null Removal of licensing factors from origins View Gene Set 3.008e-07 78 4.659e-06 72 REACTOME - Removal of licensing factors from origins gene set www.pathwaycomm...
Null Mitochondrial tRNA aminoacylation View Gene Set 3.59e-07 21 5.419e-06 74 REACTOME - Mitochondrial tRNA aminoacylation gene set www.pathwaycomm...
Null Influenza Infection View Gene Set 4.288e-07 143 6.387e-06 75 REACTOME - Influenza Infection gene set www.pathwaycomm...
Null G1/S Transition View Gene Set 5.302e-07 104 7.679e-06 76 REACTOME - G1/S Transition gene set www.pathwaycomm...
Null Switching of origins to a post-replicative state View Gene Set 5.362e-07 76 7.679e-06 76 REACTOME - Switching of origins to a post-replicative state gene set www.pathwaycomm...
Null Orc1 removal from chromatin View Gene Set 5.362e-07 76 7.679e-06 76 REACTOME - Orc1 removal from chromatin gene set www.pathwaycomm...
Null Metabolism of amino acids and derivatives View Gene Set 6.627e-07 201 9.37e-06 79 REACTOME - Metabolism of amino acids and derivatives gene set www.pathwaycomm...
Null G2/M Checkpoints View Gene Set 7.784e-07 43 1.087e-05 80 REACTOME - G2/M Checkpoints gene set www.pathwaycomm...
Null Stabilization of p53 View Gene Set 9.567e-07 61 1.319e-05 81 REACTOME - Stabilization of p53 gene set www.pathwaycomm...
Null Pyruvate metabolism and Citric Acid (TCA) cycle View Gene Set 1.125e-06 31 1.533e-05 82 REACTOME - Pyruvate metabolism and Citric Acid (TCA) cycle gene set www.pathwaycomm...
Null CDT1 association with the CDC6:ORC:origin complex View Gene Set 1.176e-06 66 1.583e-05 83 REACTOME - CDT1 association with the CDC6:ORC:origin complex gene set www.pathwaycomm...
Null Mitotic G1-G1/S phases View Gene Set 1.218e-06 113 1.619e-05 84 REACTOME - Mitotic G1-G1/S phases gene set www.pathwaycomm...
Null Translation View Gene Set 1.266e-06 120 1.663e-05 85 REACTOME - Translation gene set www.pathwaycomm...
Null Regulation of activated PAK-2p34 by proteasome mediated degradation View Gene Set 1.417e-06 57 1.819e-05 86 REACTOME - Regulation of activated PAK-2p34 by proteasome mediated degradation gene set www.pathwaycomm...
Null Autodegradation of the E3 ubiquitin ligase COP1 View Gene Set 1.414e-06 60 1.819e-05 86 REACTOME - Autodegradation of the E3 ubiquitin ligase COP1 gene set www.pathwaycomm...
Null Ubiquitin-dependent degradation of Cyclin D1 View Gene Set 1.819e-06 59 2.283e-05 88 REACTOME - Ubiquitin-dependent degradation of Cyclin D1 gene set www.pathwaycomm...
Null Ubiquitin-dependent degradation of Cyclin D View Gene Set 1.819e-06 59 2.283e-05 88 REACTOME - Ubiquitin-dependent degradation of Cyclin D gene set www.pathwaycomm...
Null Deposition of New CENPA-containing Nucleosomes at the Centromere View Gene Set 1.951e-06 35 2.395e-05 90 REACTOME - Deposition of New CENPA-containing Nucleosomes at the Centromere gene set www.pathwaycomm...
Null Nucleosome assembly View Gene Set 1.951e-06 35 2.395e-05 90 REACTOME - Nucleosome assembly gene set www.pathwaycomm...
Null Degradation of beta-catenin by the destruction complex View Gene Set 2.047e-06 56 2.459e-05 92 REACTOME - Degradation of beta-catenin by the destruction complex gene set www.pathwaycomm...
Null Signaling by Wnt View Gene Set 2.047e-06 56 2.459e-05 92 REACTOME - Signaling by Wnt gene set www.pathwaycomm...
Null Influenza Life Cycle View Gene Set 2.405e-06 138 2.858e-05 94 REACTOME - Influenza Life Cycle gene set www.pathwaycomm...
Null Vpu mediated degradation of CD4 View Gene Set 2.729e-06 57 3.209e-05 95 REACTOME - Vpu mediated degradation of CD4 gene set www.pathwaycomm...
Null Vif-mediated degradation of APOBEC3G View Gene Set 2.832e-06 61 3.295e-05 96 REACTOME - Vif-mediated degradation of APOBEC3G gene set www.pathwaycomm...
Null G1/S DNA Damage Checkpoints View Gene Set 3.205e-06 68 3.691e-05 97 REACTOME - G1/S DNA Damage Checkpoints gene set www.pathwaycomm...
Null Metabolism of carbohydrates View Gene Set 4.16e-06 93 4.742e-05 98 REACTOME - Metabolism of carbohydrates gene set www.pathwaycomm...
Null CDK-mediated phosphorylation and removal of Cdc6 View Gene Set 4.215e-06 58 4.756e-05 99 REACTOME - CDK-mediated phosphorylation and removal of Cdc6 gene set www.pathwaycomm...
Null DNA Repair View Gene Set 4.433e-06 108 4.951e-05 100 REACTOME - DNA Repair gene set www.pathwaycomm...
Null Autodegradation of Cdh1 by Cdh1:APC/C View Gene Set 4.774e-06 67 5.279e-05 101 REACTOME - Autodegradation of Cdh1 by Cdh1:APC/C gene set www.pathwaycomm...
Null Activation of ATR in response to replication stress View Gene Set 5.161e-06 37 5.652e-05 102 REACTOME - Activation of ATR in response to replication stress gene set www.pathwaycomm...
Null G2/M DNA damage checkpoint View Gene Set 5.811e-06 29 6.302e-05 103 REACTOME - G2/M DNA damage checkpoint gene set www.pathwaycomm...
Null Post-Elongation Processing of Intronless pre-mRNA View Gene Set 7.974e-06 23 8.428e-05 104 REACTOME - Post-Elongation Processing of Intronless pre-mRNA gene set www.pathwaycomm...
Null Processing of Capped Intronless Pre-mRNA View Gene Set 7.974e-06 23 8.428e-05 104 REACTOME - Processing of Capped Intronless Pre-mRNA gene set www.pathwaycomm...
Null DNA strand elongation View Gene Set 7.998e-06 31 8.428e-05 104 REACTOME - DNA strand elongation gene set www.pathwaycomm...
Null Extension of Telomeres View Gene Set 9.066e-06 28 9.377e-05 107 REACTOME - Extension of Telomeres gene set www.pathwaycomm...
Null Respiratory electron transport ATP synthesis by chemiosmotic coupling and heat production by uncoupling proteins. View Gene Set 9.028e-06 91 9.377e-05 107 REACTOME - Respiratory electron transport ATP synthesis by chemiosmotic coupling and heat production by uncoupling proteins. gene set www.pathwaycomm... ATP synthesis b... and heat produc...
Null Cap-dependent Translation Initiation View Gene Set 1.02e-05 113 0.0001035 109 REACTOME - Cap-dependent Translation Initiation gene set www.pathwaycomm...
Null Eukaryotic Translation Initiation View Gene Set 1.02e-05 113 0.0001035 109 REACTOME - Eukaryotic Translation Initiation gene set www.pathwaycomm...
Null Activation of the mRNA upon binding of the cap-binding complex and eIFs and subsequent binding to 43S View Gene Set 1.297e-05 57 0.0001305 111 REACTOME - Activation of the mRNA upon binding of the cap-binding complex and eIFs and subsequent binding to 43S gene set www.pathwaycomm... and subsequent ...
Null Regulation of ornithine decarboxylase (ODC) View Gene Set 1.416e-05 62 0.0001412 112 REACTOME - Regulation of ornithine decarboxylase (ODC) gene set www.pathwaycomm...
Null p53-Dependent G1/S DNA damage checkpoint View Gene Set 1.759e-05 64 0.0001724 113 REACTOME - p53-Dependent G1/S DNA damage checkpoint gene set www.pathwaycomm...
Null p53-Dependent G1 DNA Damage Response View Gene Set 1.759e-05 64 0.0001724 113 REACTOME - p53-Dependent G1 DNA Damage Response gene set www.pathwaycomm...
Null Regulation of Apoptosis View Gene Set 1.929e-05 66 0.0001859 115 REACTOME - Regulation of Apoptosis gene set www.pathwaycomm...
Null Ribosomal scanning and start codon recognition View Gene Set 1.931e-05 56 0.0001859 115 REACTOME - Ribosomal scanning and start codon recognition gene set www.pathwaycomm...
Null Translation initiation complex formation View Gene Set 2.132e-05 56 0.0002035 117 REACTOME - Translation initiation complex formation gene set www.pathwaycomm...
Null Citric acid cycle (TCA cycle) View Gene Set 6.214e-05 19 0.0005882 118 REACTOME - Citric acid cycle (TCA cycle) gene set www.pathwaycomm...
Null Activation of the pre-replicative complex View Gene Set 6.274e-05 30 0.000589 119 REACTOME - Activation of the pre-replicative complex gene set www.pathwaycomm...
Null Homologous Recombination Repair View Gene Set 7.22e-05 22 0.0006666 120 REACTOME - Homologous Recombination Repair gene set www.pathwaycomm...
Null Homologous recombination repair of replication-independent double-strand breaks View Gene Set 7.22e-05 22 0.0006666 120 REACTOME - Homologous recombination repair of replication-independent double-strand breaks gene set www.pathwaycomm...
Null Nucleotide Excision Repair View Gene Set 8.018e-05 51 0.0007341 122 REACTOME - Nucleotide Excision Repair gene set www.pathwaycomm...
Null Pyrimidine biosynthesis View Gene Set 8.458e-05 6 0.0007681 123 REACTOME - Pyrimidine biosynthesis gene set www.pathwaycomm...
Null Phosphorylation of the APC/C View Gene Set 0.000104 26 0.0009366 124 REACTOME - Phosphorylation of the APC/C gene set www.pathwaycomm...
Null Processing of Intronless Pre-mRNAs View Gene Set 0.0001049 14 0.0009376 125 REACTOME - Processing of Intronless Pre-mRNAs gene set www.pathwaycomm...
Null RNA Polymerase III Transcription Initiation From Type 2 Promoter View Gene Set 0.0001201 20 0.001056 126 REACTOME - RNA Polymerase III Transcription Initiation From Type 2 Promoter gene set www.pathwaycomm...
Null RNA Polymerase III Transcription Initiation From Type 1 Promoter View Gene Set 0.0001201 21 0.001056 126 REACTOME - RNA Polymerase III Transcription Initiation From Type 1 Promoter gene set www.pathwaycomm...
Null Purine ribonucleoside monophosphate biosynthesis View Gene Set 0.0001302 7 0.001136 128 REACTOME - Purine ribonucleoside monophosphate biosynthesis gene set www.pathwaycomm...
Null Unwinding of DNA View Gene Set 0.0001668 11 0.001445 129 REACTOME - Unwinding of DNA gene set www.pathwaycomm...
Null Double-Strand Break Repair View Gene Set 0.0001938 27 0.001665 130 REACTOME - Double-Strand Break Repair gene set www.pathwaycomm...
Null Respiratory electron transport View Gene Set 0.0002035 76 0.001735 131 REACTOME - Respiratory electron transport gene set www.pathwaycomm...
Null SCF(Skp2)-mediated degradation of p27/p21 View Gene Set 0.0002071 52 0.001753 132 REACTOME - SCF(Skp2)-mediated degradation of p27/p21 gene set www.pathwaycomm...
Null GTP hydrolysis and joining of the 60S ribosomal subunit View Gene Set 0.0002254 106 0.001893 133 REACTOME - GTP hydrolysis and joining of the 60S ribosomal subunit gene set www.pathwaycomm...
Null Metabolism of nucleotides View Gene Set 0.0003996 66 0.003331 134 REACTOME - Metabolism of nucleotides gene set www.pathwaycomm...
Null 3' -UTR-mediated translational regulation View Gene Set 0.0004187 105 0.003439 135 REACTOME - 3' -UTR-mediated translational regulation gene set www.pathwaycomm...
Null L13a-mediated translational silencing of Ceruloplasmin expression View Gene Set 0.0004187 105 0.003439 135 REACTOME - L13a-mediated translational silencing of Ceruloplasmin expression gene set www.pathwaycomm...
Null MicroRNA (miRNA) Biogenesis View Gene Set 0.0004848 22 0.003924 137 REACTOME - MicroRNA (miRNA) Biogenesis gene set www.pathwaycomm...
Null Regulatory RNA pathways View Gene Set 0.0004848 22 0.003924 137 REACTOME - Regulatory RNA pathways gene set www.pathwaycomm...
Null RNA Polymerase I Chain Elongation View Gene Set 0.0005552 49 0.004462 139 REACTOME - RNA Polymerase I Chain Elongation gene set www.pathwaycomm...
Null Formation of tubulin folding intermediates by CCT/TriC View Gene Set 0.0005955 8 0.004751 140 REACTOME - Formation of tubulin folding intermediates by CCT/TriC gene set www.pathwaycomm...
Null RNA Polymerase III Transcription Termination View Gene Set 0.0006131 17 0.004857 141 REACTOME - RNA Polymerase III Transcription Termination gene set www.pathwaycomm...
Null RNA Polymerase I Transcription View Gene Set 0.0006303 57 0.004958 142 REACTOME - RNA Polymerase I Transcription gene set www.pathwaycomm...
Null Deadenylation of mRNA View Gene Set 0.0007424 22 0.005799 143 REACTOME - Deadenylation of mRNA gene set www.pathwaycomm...
Null Recycling of eIF2:GDP View Gene Set 0.0007588 8 0.005886 144 REACTOME - Recycling of eIF2:GDP gene set www.pathwaycomm...
Null Telomere Extension By Telomerase View Gene Set 0.0007668 6 0.005907 145 REACTOME - Telomere Extension By Telomerase gene set www.pathwaycomm...
Null Packaging Of Telomere Ends View Gene Set 0.0007742 21 0.005923 146 REACTOME - Packaging Of Telomere Ends gene set www.pathwaycomm...
Null Gap-filling DNA repair synthesis and ligation in TC-NER View Gene Set 0.0008076 16 0.006014 147 REACTOME - Gap-filling DNA repair synthesis and ligation in TC-NER gene set www.pathwaycomm...
Null Gap-filling DNA repair synthesis and ligation in GG-NER View Gene Set 0.0008076 16 0.006014 147 REACTOME - Gap-filling DNA repair synthesis and ligation in GG-NER gene set www.pathwaycomm...
Null Removal of DNA patch containing abasic residue View Gene Set 0.0007989 17 0.006014 147 REACTOME - Removal of DNA patch containing abasic residue gene set www.pathwaycomm...
Null Resolution of AP sites via the multiple-nucleotide patch replacement pathway View Gene Set 0.0007989 17 0.006014 147 REACTOME - Resolution of AP sites via the multiple-nucleotide patch replacement pathway gene set www.pathwaycomm...
Null Telomere C-strand (Lagging Strand) Synthesis View Gene Set 0.0008145 22 0.006026 151 REACTOME - Telomere C-strand (Lagging Strand) Synthesis gene set www.pathwaycomm...
Null Polo-like kinase mediated events View Gene Set 0.0008715 10 0.006404 152 REACTOME - Polo-like kinase mediated events gene set www.pathwaycomm...
Null RNA Polymerase III Transcription View Gene Set 0.0009869 34 0.007158 153 REACTOME - RNA Polymerase III Transcription gene set www.pathwaycomm...
Null RNA Polymerase III Abortive And Retractive Initiation View Gene Set 0.0009869 34 0.007158 153 REACTOME - RNA Polymerase III Abortive And Retractive Initiation gene set www.pathwaycomm...
Null Cyclin A:Cdk2-associated events at S phase entry View Gene Set 0.001099 62 0.007919 155 REACTOME - Cyclin A:Cdk2-associated events at S phase entry gene set www.pathwaycomm...
Null Transcription-coupled NER (TC-NER) View Gene Set 0.001146 45 0.008157 156 REACTOME - Transcription-coupled NER (TC-NER) gene set www.pathwaycomm...
Null Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase View Gene Set 0.00114 16 0.008157 156 REACTOME - Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase gene set www.pathwaycomm...
Null MRN complex relocalizes to nuclear foci View Gene Set 0.001238 4 0.008644 158 REACTOME - MRN complex relocalizes to nuclear foci gene set www.pathwaycomm...
Null Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks View Gene Set 0.001238 4 0.008644 158 REACTOME - Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks gene set www.pathwaycomm...
Null mRNA Decay by 3' to 5' Exoribonuclease View Gene Set 0.001231 11 0.008644 158 REACTOME - mRNA Decay by 3' to 5' Exoribonuclease gene set www.pathwaycomm...
Null Formation of the ternary complex and subsequently the 43S complex View Gene Set 0.001386 49 0.009614 161 REACTOME - Formation of the ternary complex and subsequently the 43S complex gene set www.pathwaycomm... and subsequentl... the 43S complex...
Null RNA Polymerase I Promoter Clearance View Gene Set 0.00143 55 0.00986 162 REACTOME - RNA Polymerase I Promoter Clearance gene set www.pathwaycomm...
Null RNA Polymerase I Promoter Opening View Gene Set 0.001559 31 0.01037 163 REACTOME - RNA Polymerase I Promoter Opening gene set www.pathwaycomm...
Null ATM mediated phosphorylation of repair proteins View Gene Set 0.001559 6 0.01037 163 REACTOME - ATM mediated phosphorylation of repair proteins gene set www.pathwaycomm...
Null ATM mediated response to DNA double-strand break View Gene Set 0.001559 6 0.01037 163 REACTOME - ATM mediated response to DNA double-strand break gene set www.pathwaycomm...
Null Base Excision Repair View Gene Set 0.001545 19 0.01037 163 REACTOME - Base Excision Repair gene set www.pathwaycomm...
Null Resolution of Abasic Sites (AP sites) View Gene Set 0.001545 19 0.01037 163 REACTOME - Resolution of Abasic Sites (AP sites) gene set www.pathwaycomm...
Null Mitotic Telophase /Cytokinesis View Gene Set 0.001549 10 0.01037 163 REACTOME - Mitotic Telophase /Cytokinesis gene set www.pathwaycomm...
Null Mitotic Spindle Checkpoint View Gene Set 0.001593 19 0.01053 169 REACTOME - Mitotic Spindle Checkpoint gene set www.pathwaycomm...
Null Recruitment of repair and signaling proteins to double-strand breaks View Gene Set 0.002149 8 0.01412 170 REACTOME - Recruitment of repair and signaling proteins to double-strand breaks gene set www.pathwaycomm...
Null Lysine catabolism View Gene Set 0.00217 8 0.01417 171 REACTOME - Lysine catabolism gene set www.pathwaycomm...
Null Repair synthesis for gap-filling by DNA polymerase in TC-NER View Gene Set 0.002394 15 0.01546 172 REACTOME - Repair synthesis for gap-filling by DNA polymerase in TC-NER gene set www.pathwaycomm...
Null Repair synthesis of patch ~27-30 bases long by DNA polymerase View Gene Set 0.002394 15 0.01546 172 REACTOME - Repair synthesis of patch ~27-30 bases long by DNA polymerase gene set www.pathwaycomm...
Null Pyrimidine metabolism View Gene Set 0.002748 23 0.01764 174 REACTOME - Pyrimidine metabolism gene set www.pathwaycomm...
Null Pyruvate metabolism View Gene Set 0.002924 10 0.01828 175 REACTOME - Pyruvate metabolism gene set www.pathwaycomm...
Null Mitochondrial transcription initiation View Gene Set 0.002929 3 0.01828 175 REACTOME - Mitochondrial transcription initiation gene set www.pathwaycomm...
Null Association of TriC/CCT with target proteins during biosynthesis View Gene Set 0.002875 9 0.01828 175 REACTOME - Association of TriC/CCT with target proteins during biosynthesis gene set www.pathwaycomm...
Null Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components View Gene Set 0.002902 18 0.01828 175 REACTOME - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components gene set www.pathwaycomm...
Null Inactivation of APC/C via direct inhibition of the APC/C complex View Gene Set 0.002902 18 0.01828 175 REACTOME - Inactivation of APC/C via direct inhibition of the APC/C complex gene set www.pathwaycomm...
Null Global Genomic NER (GG-NER) View Gene Set 0.00295 35 0.01831 180 REACTOME - Global Genomic NER (GG-NER) gene set www.pathwaycomm...
Null Cyclin E associated events during G1/S transition View Gene Set 0.003162 64 0.01951 181 REACTOME - Cyclin E associated events during G1/S transition gene set www.pathwaycomm...
Null mTORC1-mediated signalling View Gene Set 0.003341 11 0.02051 182 REACTOME - mTORC1-mediated signalling gene set www.pathwaycomm...
Null SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs View Gene Set 0.003633 11 0.02217 183 REACTOME - SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs gene set www.pathwaycomm...
Null Lagging Strand Synthesis View Gene Set 0.0038 20 0.02307 184 REACTOME - Lagging Strand Synthesis gene set www.pathwaycomm...
Null Abortive elongation of HIV-1 transcript in the absence of Tat View Gene Set 0.004035 22 0.02436 185 REACTOME - Abortive elongation of HIV-1 transcript in the absence of Tat gene set www.pathwaycomm...
Null Transcription from mitochondrial promoters View Gene Set 0.004437 4 0.02665 186 REACTOME - Transcription from mitochondrial promoters gene set www.pathwaycomm...
Null RNA Polymerase III Chain Elongation View Gene Set 0.004523 12 0.02702 187 REACTOME - RNA Polymerase III Chain Elongation gene set www.pathwaycomm...
Null SLBP independent Processing of Histone Pre-mRNAs View Gene Set 0.004752 10 0.02809 188 REACTOME - SLBP independent Processing of Histone Pre-mRNAs gene set www.pathwaycomm...
Null Processive synthesis on the C-strand of the telomere View Gene Set 0.004752 11 0.02809 188 REACTOME - Processive synthesis on the C-strand of the telomere gene set www.pathwaycomm...
Null Formation of ATP by chemiosmotic coupling View Gene Set 0.004818 15 0.02833 190 REACTOME - Formation of ATP by chemiosmotic coupling gene set www.pathwaycomm...
Null Regulation of pyruvate dehydrogenase (PDH) complex View Gene Set 0.005194 9 0.03038 191 REACTOME - Regulation of pyruvate dehydrogenase (PDH) complex gene set www.pathwaycomm...
Null Folding of actin by CCT/TriC View Gene Set 0.005441 9 0.03165 192 REACTOME - Folding of actin by CCT/TriC gene set www.pathwaycomm...
Null RNA Polymerase III Transcription Initiation View Gene Set 0.005494 29 0.0318 193 REACTOME - RNA Polymerase III Transcription Initiation gene set www.pathwaycomm...
Null NS1 Mediated Effects on Host Pathways View Gene Set 0.005764 3 0.03319 194 REACTOME - NS1 Mediated Effects on Host Pathways gene set www.pathwaycomm...
Null Phosphorylation of Emi1 View Gene Set 0.005974 12 0.03422 195 REACTOME - Phosphorylation of Emi1 gene set www.pathwaycomm...
Null Displacement of DNA glycosylase by APE1 View Gene Set 0.006546 9 0.0373 196 REACTOME - Displacement of DNA glycosylase by APE1 gene set www.pathwaycomm...
Null mRNA Decay by 5' to 3' Exoribonuclease View Gene Set 0.006894 13 0.03909 197 REACTOME - mRNA Decay by 5' to 3' Exoribonuclease gene set www.pathwaycomm...
Null Release of eIF4E View Gene Set 0.00753 7 0.04248 198 REACTOME - Release of eIF4E gene set www.pathwaycomm...
Null Vitamin B5 (pantothenate) metabolism View Gene Set 0.007722 9 0.04334 199 REACTOME - Vitamin B5 (pantothenate) metabolism gene set www.pathwaycomm...
Null Prefoldin mediated transfer of substrate to CCT/TriC View Gene Set 0.008157 14 0.04556 200 REACTOME - Prefoldin mediated transfer of substrate to CCT/TriC gene set www.pathwaycomm...

Gene Set Collection: mirbase.targets

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-146b-3p View Gene Set 4.458e-06 695 0.00219 1 microRNA targets for hsa-miR-146b-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-874 View Gene Set 6.16e-06 722 0.00219 1 microRNA targets for hsa-miR-874 from mirbase.targets www.mirbase.org...
Null hsa-miR-383 View Gene Set 4.763e-05 748 0.007261 3 microRNA targets for hsa-miR-383 from mirbase.targets www.mirbase.org...
Null hsa-miR-503 View Gene Set 8.17e-05 748 0.007261 3 microRNA targets for hsa-miR-503 from mirbase.targets www.mirbase.org...
Null hsa-miR-671-3p View Gene Set 8.097e-05 767 0.007261 3 microRNA targets for hsa-miR-671-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-886-5p View Gene Set 6.942e-05 793 0.007261 3 microRNA targets for hsa-miR-886-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-923 View Gene Set 4.181e-05 690 0.007261 3 microRNA targets for hsa-miR-923 from mirbase.targets www.mirbase.org...
Null hsa-miR-99b View Gene Set 8.075e-05 708 0.007261 3 microRNA targets for hsa-miR-99b from mirbase.targets www.mirbase.org...
Null hsa-miR-424 View Gene Set 0.0001121 772 0.008854 9 microRNA targets for hsa-miR-424 from mirbase.targets www.mirbase.org...
Null hsa-miR-635 View Gene Set 0.0002661 648 0.01892 10 microRNA targets for hsa-miR-635 from mirbase.targets www.mirbase.org...
Null hsa-miR-634 View Gene Set 0.0003624 714 0.02342 11 microRNA targets for hsa-miR-634 from mirbase.targets www.mirbase.org...
Null hsa-let-7f View Gene Set 0.0005999 753 0.03171 12 microRNA targets for hsa-let-7f from mirbase.targets www.mirbase.org...
Null hsa-miR-331-3p View Gene Set 0.0006243 712 0.03171 12 microRNA targets for hsa-miR-331-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-455-3p View Gene Set 0.0006048 824 0.03171 12 microRNA targets for hsa-miR-455-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-486-3p View Gene Set 0.0006835 773 0.0324 15 microRNA targets for hsa-miR-486-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-29a View Gene Set 0.0007589 828 0.03372 16 microRNA targets for hsa-miR-29a from mirbase.targets www.mirbase.org...
Null hsa-miR-345 View Gene Set 0.001081 696 0.04519 17 microRNA targets for hsa-miR-345 from mirbase.targets www.mirbase.org...
Null hsa-miR-208 View Gene Set 0.001238 664 0.04889 18 microRNA targets for hsa-miR-208 from mirbase.targets www.mirbase.org...

Gene Set Collection: tarbase.targets

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-let-7b View Gene Set 0.001226 83 0.03779 1 microRNA targets for hsa-let-7b from tarbase.targets www.mirbase.org...
Null hsa-miR-16 View Gene Set 0.001482 91 0.03779 1 microRNA targets for hsa-miR-16 from tarbase.targets www.mirbase.org...

Gene Set Collection: tfbsK3Z3

Arguments: refPop=all, featureType=featureNames, colname=WilcoxDOWN, ranks.only=TRUE, absolute=FALSE, alternative=down

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null V_E2F_02 View Gene Set 1.962e-06 134 0.000418 1 List of genes containing a conserved (FDR < 0.1%) V$E2F_02 TFBS located within 3 kb around the TSS for the E2F transcription factor www.gene-regula...
Null V_MYCMAX_01 View Gene Set 0.0001154 136 0.01175 2 List of genes containing a conserved (FDR < 0.1%) V$MYCMAX_01 TFBS located within 3 kb around the TSS for the c-Myc transcription factor www.gene-regula...
Null V_NFY_C View Gene Set 0.0001655 17 0.01175 2 List of genes containing a conserved (FDR < 0.1%) V$NFY_C TFBS located within 3 kb around the TSS for the CP1A transcription factor www.gene-regula...