Results

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Go to: Gene Set Collection: KEGG
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Go to: Gene Set Collection: Broad.c2.CP.BIOCARTA
Go to: Gene Set Collection: Broad.c2.CP.KEGG
Go to: Gene Set Collection: Broad.c2.CP.REACTOME
Go to: Gene Set Collection: Broad.c3.TFT
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Go to: Gene Set Collection: Broad.c5.BP
Go to: Gene Set Collection: Broad.c5.CC
Go to: Gene Set Collection: Broad.c5.MF
Go to: Gene Set Collection: PMID
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Go to: Gene Set Collection: Enzyme
Go to: Gene Set Collection: pathwayCommons.reactome
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Go to: Gene Set Collection: hprdManual.DIFFERENT
Go to: Gene Set Collection: tfbsK3Z3

AFA results for: AllvsControl

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Gene Set Collection: KEGG

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
KEGG 04080 View Gene Set 1.096e-10 272 2.346e-08 1 Neuroactive ligand-receptor interaction www.genome.jp/d...
KEGG 04060 View Gene Set 9.349e-09 266 1e-06 2 Cytokine-cytokine receptor interaction www.genome.jp/d...
KEGG 04514 View Gene Set 1.713e-07 135 1.049e-05 3 Cell adhesion molecules (CAMs) www.genome.jp/d...
KEGG 04740 View Gene Set 1.961e-07 388 1.049e-05 3 Olfactory transduction www.genome.jp/d...
KEGG 05332 View Gene Set 8.62e-07 43 3.689e-05 5 Graft-versus-host disease www.genome.jp/d...
KEGG 05320 View Gene Set 1.763e-06 54 6.287e-05 6 Autoimmune thyroid disease www.genome.jp/d...
KEGG 05330 View Gene Set 2.595e-06 39 7.933e-05 7 Allograft rejection www.genome.jp/d...
KEGG 04512 View Gene Set 3.774e-06 84 0.000101 8 ECM-receptor interaction www.genome.jp/d...
KEGG 04940 View Gene Set 9.064e-06 45 0.0002155 9 Type I diabetes mellitus www.genome.jp/d...
KEGG 04610 View Gene Set 2.108e-05 69 0.0004512 10 Complement and coagulation cascades www.genome.jp/d...
KEGG 00980 View Gene Set 3.04e-05 71 0.0005915 11 Metabolism of xenobiotics by cytochrome P450 www.genome.jp/d...
KEGG 00140 View Gene Set 0.0001001 56 0.001785 12 Steroid hormone biosynthesis www.genome.jp/d...
KEGG 04640 View Gene Set 0.0001354 88 0.002229 13 Hematopoietic cell lineage www.genome.jp/d...
KEGG 04020 View Gene Set 0.0001761 178 0.002692 14 Calcium signaling pathway www.genome.jp/d...
KEGG 04950 View Gene Set 0.000433 25 0.006177 15 Maturity onset diabetes of the young www.genome.jp/d...
KEGG 00982 View Gene Set 0.0005058 73 0.006765 16 Drug metabolism - cytochrome P450 www.genome.jp/d...
KEGG 05144 View Gene Set 0.0007994 51 0.01006 17 Malaria www.genome.jp/d...
KEGG 00591 View Gene Set 0.001015 29 0.01207 18 Linoleic acid metabolism www.genome.jp/d...
KEGG 04742 View Gene Set 0.001341 52 0.0151 19 Taste transduction www.genome.jp/d...
KEGG 00830 View Gene Set 0.001478 65 0.01582 20 Retinol metabolism www.genome.jp/d...
KEGG 04672 View Gene Set 0.001757 49 0.0179 21 Intestinal immune network for IgA production www.genome.jp/d...
KEGG 00053 View Gene Set 0.002178 26 0.02119 22 Ascorbate and aldarate metabolism www.genome.jp/d...
KEGG 00590 View Gene Set 0.002696 58 0.02509 23 Arachidonic acid metabolism www.genome.jp/d...
KEGG 00500 View Gene Set 0.003593 53 0.03204 24 Starch and sucrose metabolism www.genome.jp/d...
KEGG 00040 View Gene Set 0.004781 29 0.04093 25 Pentose and glucuronate interconversions www.genome.jp/d...
KEGG 05414 View Gene Set 0.005316 92 0.04376 26 Dilated cardiomyopathy www.genome.jp/d...

Gene Set Collection: GO

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
GO GO:0005576 View Gene Set 1.099e-63 2036 1.469e-59 1 extracellular region amigo.geneontol...
GO GO:0032501 View Gene Set 2.674e-49 4631 1.787e-45 2 multicellular organismal process amigo.geneontol...
GO GO:0044421 View Gene Set 2.556e-44 1001 1.138e-40 3 extracellular region part amigo.geneontol...
GO GO:0005886 View Gene Set 4.238e-43 3759 1.415e-39 4 plasma membrane amigo.geneontol...
GO GO:0004872 View Gene Set 6.071e-36 1688 1.622e-32 5 receptor activity amigo.geneontol...
GO GO:0004871 View Gene Set 2.319e-33 2128 4.426e-30 6 signal transducer activity amigo.geneontol...
GO GO:0060089 View Gene Set 2.319e-33 2128 4.426e-30 6 molecular transducer activity amigo.geneontol...
GO GO:0004888 View Gene Set 3.065e-31 1275 5.119e-28 8 transmembrane receptor activity amigo.geneontol...
GO GO:0031012 View Gene Set 1.494e-30 371 2.217e-27 9 extracellular matrix amigo.geneontol...
GO GO:0003008 View Gene Set 2.427e-30 1632 3.242e-27 10 system process amigo.geneontol...
GO GO:0005615 View Gene Set 5.513e-29 752 6.696e-26 11 extracellular space amigo.geneontol...
GO GO:0044459 View Gene Set 9.44e-27 2023 1.051e-23 12 plasma membrane part amigo.geneontol...
GO GO:0048731 View Gene Set 1.306e-24 2544 1.342e-21 13 system development amigo.geneontol...
GO GO:0007275 View Gene Set 2.188e-24 3067 2.088e-21 14 multicellular organismal development amigo.geneontol...
GO GO:0005578 View Gene Set 3.079e-24 313 2.742e-21 15 proteinaceous extracellular matrix amigo.geneontol...
GO GO:0050877 View Gene Set 6.277e-24 1272 5.242e-21 16 neurological system process amigo.geneontol...
GO GO:0048856 View Gene Set 2.56e-22 2763 2.012e-19 17 anatomical structure development amigo.geneontol...
GO GO:0031224 View Gene Set 2.683e-21 5387 1.991e-18 18 intrinsic to membrane amigo.geneontol...
GO GO:0030154 View Gene Set 1.314e-20 1834 9.239e-18 19 cell differentiation amigo.geneontol...
GO GO:0032502 View Gene Set 1.887e-20 3351 1.261e-17 20 developmental process amigo.geneontol...
GO GO:0031226 View Gene Set 4.42e-20 1208 2.812e-17 21 intrinsic to plasma membrane amigo.geneontol...
GO GO:0005887 View Gene Set 1.478e-19 1186 8.974e-17 22 integral to plasma membrane amigo.geneontol...
GO GO:0048869 View Gene Set 2.582e-19 1883 1.5e-16 23 cellular developmental process amigo.geneontol...
GO GO:0007267 View Gene Set 3.98e-19 720 2.216e-16 24 cell-cell signaling amigo.geneontol...
GO GO:0004930 View Gene Set 1.335e-18 855 7.132e-16 25 G-protein coupled receptor activity amigo.geneontol...
GO GO:0007155 View Gene Set 3.416e-18 827 1.755e-15 26 cell adhesion amigo.geneontol...
GO GO:0022610 View Gene Set 5.017e-18 828 2.483e-15 27 biological adhesion amigo.geneontol...
GO GO:0007166 View Gene Set 8.131e-18 1497 3.88e-15 28 cell surface receptor linked signaling pathway amigo.geneontol...
GO GO:0016021 View Gene Set 8.654e-18 5278 3.987e-15 29 integral to membrane amigo.geneontol...
GO GO:0051239 View Gene Set 5.379e-17 1088 2.395e-14 30 regulation of multicellular organismal process amigo.geneontol...
GO GO:0044425 View Gene Set 1.213e-16 6145 5.227e-14 31 membrane part amigo.geneontol...
GO GO:0048513 View Gene Set 1.391e-16 1931 5.808e-14 32 organ development amigo.geneontol...
GO GO:0007600 View Gene Set 5.653e-16 830 2.288e-13 33 sensory perception amigo.geneontol...
GO GO:0023052 View Gene Set 1.036e-15 3571 4.072e-13 34 signaling amigo.geneontol...
GO GO:0007154 View Gene Set 7.047e-15 1687 2.69e-12 35 cell communication amigo.geneontol...
GO GO:0015267 View Gene Set 8.748e-15 409 3.247e-12 36 channel activity amigo.geneontol...
GO GO:0007186 View Gene Set 1.188e-14 543 4.29e-12 37 G-protein coupled receptor protein signaling pathway amigo.geneontol...
GO GO:0022803 View Gene Set 1.242e-14 410 4.368e-12 38 passive transmembrane transporter activity amigo.geneontol...
GO GO:0006955 View Gene Set 1.747e-14 732 5.983e-12 39 immune response amigo.geneontol...
GO GO:0005216 View Gene Set 4.03e-14 382 1.346e-11 40 ion channel activity amigo.geneontol...
GO GO:0022838 View Gene Set 4.226e-14 393 1.377e-11 41 substrate-specific channel activity amigo.geneontol...
GO GO:0007399 View Gene Set 1.527e-12 1174 4.856e-10 42 nervous system development amigo.geneontol...
GO GO:0007610 View Gene Set 2.453e-12 492 7.62e-10 43 behavior amigo.geneontol...
GO GO:0022836 View Gene Set 3.135e-12 309 9.518e-10 44 gated channel activity amigo.geneontol...
GO GO:0016020 View Gene Set 3.523e-12 7286 1.046e-09 45 membrane amigo.geneontol...
GO GO:0031225 View Gene Set 6.151e-12 133 1.787e-09 46 anchored to membrane amigo.geneontol...
GO GO:0030246 View Gene Set 7.821e-12 367 2.223e-09 47 carbohydrate binding amigo.geneontol...
GO GO:0009611 View Gene Set 8.361e-12 621 2.327e-09 48 response to wounding amigo.geneontol...
GO GO:0005201 View Gene Set 1.104e-11 81 3.011e-09 49 extracellular matrix structural constituent amigo.geneontol...
GO GO:0009888 View Gene Set 1.349e-11 827 3.605e-09 50 tissue development amigo.geneontol...
GO GO:0009653 View Gene Set 1.579e-11 1301 4.135e-09 51 anatomical structure morphogenesis amigo.geneontol...
GO GO:0005261 View Gene Set 2.405e-11 271 6.18e-09 52 cation channel activity amigo.geneontol...
GO GO:0006952 View Gene Set 2.89e-11 717 7.285e-09 53 defense response amigo.geneontol...
GO GO:0002376 View Gene Set 3.119e-11 1101 7.717e-09 54 immune system process amigo.geneontol...
GO GO:0044420 View Gene Set 8.276e-11 112 2.01e-08 55 extracellular matrix part amigo.geneontol...
GO GO:0023046 View Gene Set 2.062e-10 2577 4.919e-08 56 signaling process amigo.geneontol...
GO GO:0023060 View Gene Set 3.428e-10 2571 8.035e-08 57 signal transmission amigo.geneontol...
GO GO:0001871 View Gene Set 4.547e-10 166 1.03e-07 58 pattern binding amigo.geneontol...
GO GO:0030247 View Gene Set 4.547e-10 166 1.03e-07 58 polysaccharide binding amigo.geneontol...
GO GO:0006954 View Gene Set 5.333e-10 380 1.188e-07 60 inflammatory response amigo.geneontol...
GO GO:0030182 View Gene Set 8.642e-10 546 1.893e-07 61 neuron differentiation amigo.geneontol...
GO GO:0008083 View Gene Set 9.461e-10 161 2.039e-07 62 growth factor activity amigo.geneontol...
GO GO:0048699 View Gene Set 1.053e-09 601 2.216e-07 63 generation of neurons amigo.geneontol...
GO GO:0005539 View Gene Set 1.062e-09 151 2.216e-07 63 glycosaminoglycan binding amigo.geneontol...
GO GO:0007606 View Gene Set 1.132e-09 478 2.326e-07 65 sensory perception of chemical stimulus amigo.geneontol...
GO GO:0003013 View Gene Set 1.957e-09 250 3.903e-07 66 circulatory system process amigo.geneontol...
GO GO:0008015 View Gene Set 1.957e-09 250 3.903e-07 66 blood circulation amigo.geneontol...
GO GO:0005125 View Gene Set 2.549e-09 201 5.008e-07 68 cytokine activity amigo.geneontol...
GO GO:0022008 View Gene Set 4.883e-09 646 9.454e-07 69 neurogenesis amigo.geneontol...
GO GO:0030855 View Gene Set 5.186e-09 194 9.898e-07 70 epithelial cell differentiation amigo.geneontol...
GO GO:0048705 View Gene Set 5.908e-09 123 1.112e-06 71 skeletal system morphogenesis amigo.geneontol...
GO GO:0007626 View Gene Set 6.542e-09 300 1.214e-06 72 locomotory behavior amigo.geneontol...
GO GO:0044057 View Gene Set 7.094e-09 315 1.298e-06 73 regulation of system process amigo.geneontol...
GO GO:0048878 View Gene Set 9.502e-09 563 1.716e-06 74 chemical homeostasis amigo.geneontol...
GO GO:0007608 View Gene Set 9.889e-09 432 1.762e-06 75 sensory perception of smell amigo.geneontol...
GO GO:0034702 View Gene Set 1.351e-08 210 2.374e-06 76 ion channel complex amigo.geneontol...
GO GO:0009187 View Gene Set 1.453e-08 147 2.521e-06 77 cyclic nucleotide metabolic process amigo.geneontol...
GO GO:0006873 View Gene Set 1.726e-08 405 2.956e-06 78 cellular ion homeostasis amigo.geneontol...
GO GO:0005509 View Gene Set 1.763e-08 626 2.981e-06 79 calcium ion binding amigo.geneontol...
GO GO:0030054 View Gene Set 2.05e-08 539 3.424e-06 80 cell junction amigo.geneontol...
GO GO:0055082 View Gene Set 2.131e-08 411 3.515e-06 81 cellular chemical homeostasis amigo.geneontol...
GO GO:0050801 View Gene Set 2.456e-08 441 4.002e-06 82 ion homeostasis amigo.geneontol...
GO GO:0022843 View Gene Set 2.567e-08 143 4.132e-06 83 voltage-gated cation channel activity amigo.geneontol...
GO GO:0001501 View Gene Set 2.662e-08 277 4.235e-06 84 skeletal system development amigo.geneontol...
GO GO:0005102 View Gene Set 3.675e-08 928 5.777e-06 85 receptor binding amigo.geneontol...
GO GO:0019226 View Gene Set 4.195e-08 421 6.517e-06 86 transmission of nerve impulse amigo.geneontol...
GO GO:0007268 View Gene Set 4.97e-08 362 7.632e-06 87 synaptic transmission amigo.geneontol...
GO GO:0006875 View Gene Set 5.168e-08 215 7.801e-06 88 cellular metal ion homeostasis amigo.geneontol...
GO GO:2000026 View Gene Set 5.197e-08 625 7.801e-06 88 regulation of multicellular organismal development amigo.geneontol...
GO GO:0004984 View Gene Set 5.4e-08 419 7.842e-06 90 olfactory receptor activity amigo.geneontol...
GO GO:0005244 View Gene Set 5.377e-08 190 7.842e-06 90 voltage-gated ion channel activity amigo.geneontol...
GO GO:0022832 View Gene Set 5.377e-08 190 7.842e-06 90 voltage-gated channel activity amigo.geneontol...
GO GO:0043062 View Gene Set 5.674e-08 174 8.151e-06 93 extracellular structure organization amigo.geneontol...
GO GO:0050896 View Gene Set 6.312e-08 3765 8.971e-06 94 response to stimulus amigo.geneontol...
GO GO:0042611 View Gene Set 8.253e-08 36 1.161e-05 95 MHC protein complex amigo.geneontol...
GO GO:0007204 View Gene Set 9.827e-08 134 1.368e-05 96 elevation of cytosolic calcium ion concentration amigo.geneontol...
GO GO:0007423 View Gene Set 1.028e-07 251 1.416e-05 97 sensory organ development amigo.geneontol...
GO GO:0046058 View Gene Set 1.116e-07 124 1.521e-05 98 cAMP metabolic process amigo.geneontol...
GO GO:0005882 View Gene Set 1.141e-07 178 1.539e-05 99 intermediate filament amigo.geneontol...
GO GO:0007398 View Gene Set 1.158e-07 218 1.547e-05 100 ectoderm development amigo.geneontol...
GO GO:0048562 View Gene Set 1.284e-07 138 1.699e-05 101 embryonic organ morphogenesis amigo.geneontol...
GO GO:0008544 View Gene Set 1.376e-07 203 1.802e-05 102 epidermis development amigo.geneontol...
GO GO:0030799 View Gene Set 1.539e-07 125 1.996e-05 103 regulation of cyclic nucleotide metabolic process amigo.geneontol...
GO GO:0008201 View Gene Set 1.573e-07 113 2.021e-05 104 heparin binding amigo.geneontol...
GO GO:0009190 View Gene Set 1.76e-07 128 2.198e-05 105 cyclic nucleotide biosynthetic process amigo.geneontol...
GO GO:0048468 View Gene Set 1.744e-07 804 2.198e-05 105 cell development amigo.geneontol...
GO GO:0055065 View Gene Set 1.744e-07 225 2.198e-05 105 metal ion homeostasis amigo.geneontol...
GO GO:0009887 View Gene Set 1.88e-07 659 2.326e-05 108 organ morphogenesis amigo.geneontol...
GO GO:0006874 View Gene Set 2.709e-07 204 3.31e-05 109 cellular calcium ion homeostasis amigo.geneontol...
GO GO:0030802 View Gene Set 2.769e-07 120 3.31e-05 109 regulation of cyclic nucleotide biosynthetic process amigo.geneontol...
GO GO:0030808 View Gene Set 2.769e-07 120 3.31e-05 109 regulation of nucleotide biosynthetic process amigo.geneontol...
GO GO:0045165 View Gene Set 2.775e-07 143 3.31e-05 109 cell fate commitment amigo.geneontol...
GO GO:0030198 View Gene Set 2.855e-07 103 3.375e-05 113 extracellular matrix organization amigo.geneontol...
GO GO:0051480 View Gene Set 3.071e-07 143 3.599e-05 114 cytosolic calcium ion homeostasis amigo.geneontol...
GO GO:0050793 View Gene Set 3.104e-07 748 3.606e-05 115 regulation of developmental process amigo.geneontol...
GO GO:0009605 View Gene Set 3.936e-07 666 4.495e-05 116 response to external stimulus amigo.geneontol...
GO GO:0009897 View Gene Set 3.91e-07 140 4.495e-05 116 external side of plasma membrane amigo.geneontol...
GO GO:0051094 View Gene Set 4.298e-07 352 4.866e-05 118 positive regulation of developmental process amigo.geneontol...
GO GO:0009986 View Gene Set 4.818e-07 350 5.409e-05 119 cell surface amigo.geneontol...
GO GO:0006140 View Gene Set 4.879e-07 283 5.432e-05 120 regulation of nucleotide metabolic process amigo.geneontol...
GO GO:0055074 View Gene Set 5.388e-07 211 5.949e-05 121 calcium ion homeostasis amigo.geneontol...
GO GO:0005581 View Gene Set 5.603e-07 35 6.136e-05 122 collagen amigo.geneontol...
GO GO:0005089 View Gene Set 5.993e-07 72 6.509e-05 123 Rho guanyl-nucleotide exchange factor activity amigo.geneontol...
GO GO:0001775 View Gene Set 6.141e-07 389 6.616e-05 124 cell activation amigo.geneontol...
GO GO:0045202 View Gene Set 8.126e-07 371 8.686e-05 125 synapse amigo.geneontol...
GO GO:0007167 View Gene Set 8.519e-07 475 9.033e-05 126 enzyme linked receptor protein signaling pathway amigo.geneontol...
GO GO:0023033 View Gene Set 8.641e-07 2547 9.09e-05 127 signaling pathway amigo.geneontol...
GO GO:0051241 View Gene Set 9.243e-07 191 9.647e-05 128 negative regulation of multicellular organismal process amigo.geneontol...
GO GO:0000904 View Gene Set 9.639e-07 305 9.983e-05 129 cell morphogenesis involved in differentiation amigo.geneontol...
GO GO:0048663 View Gene Set 9.724e-07 39 9.993e-05 130 neuron fate commitment amigo.geneontol...
GO GO:0022603 View Gene Set 1.027e-06 256 0.0001047 131 regulation of anatomical structure morphogenesis amigo.geneontol...
GO GO:0031279 View Gene Set 1.087e-06 99 0.00011 132 regulation of cyclase activity amigo.geneontol...
GO GO:0003001 View Gene Set 1.195e-06 187 0.0001171 133 generation of a signal involved in cell-cell signaling amigo.geneontol...
GO GO:0007601 View Gene Set 1.21e-06 218 0.0001171 133 visual perception amigo.geneontol...
GO GO:0010817 View Gene Set 1.209e-06 237 0.0001171 133 regulation of hormone levels amigo.geneontol...
GO GO:0023061 View Gene Set 1.195e-06 187 0.0001171 133 signal release amigo.geneontol...
GO GO:0050953 View Gene Set 1.21e-06 218 0.0001171 133 sensory perception of light stimulus amigo.geneontol...
GO GO:0045111 View Gene Set 1.185e-06 187 0.0001171 133 intermediate filament cytoskeleton amigo.geneontol...
GO GO:0001944 View Gene Set 1.252e-06 338 0.0001202 139 vasculature development amigo.geneontol...
GO GO:0006171 View Gene Set 1.26e-06 114 0.0001202 139 cAMP biosynthetic process amigo.geneontol...
GO GO:0046903 View Gene Set 1.309e-06 502 0.000124 141 secretion amigo.geneontol...
GO GO:0030817 View Gene Set 1.349e-06 112 0.0001269 142 regulation of cAMP biosynthetic process amigo.geneontol...
GO GO:0048514 View Gene Set 1.434e-06 280 0.0001339 143 blood vessel morphogenesis amigo.geneontol...
GO GO:0003002 View Gene Set 1.461e-06 226 0.0001355 144 regionalization amigo.geneontol...
GO GO:0051046 View Gene Set 1.471e-06 243 0.0001355 144 regulation of secretion amigo.geneontol...
GO GO:0030814 View Gene Set 1.584e-06 114 0.0001449 146 regulation of cAMP metabolic process amigo.geneontol...
GO GO:0005085 View Gene Set 1.612e-06 150 0.0001465 147 guanyl-nucleotide exchange factor activity amigo.geneontol...
GO GO:0007411 View Gene Set 1.697e-06 97 0.0001532 148 axon guidance amigo.geneontol...
GO GO:0005604 View Gene Set 1.77e-06 73 0.0001587 149 basement membrane amigo.geneontol...
GO GO:0048568 View Gene Set 2.231e-06 214 0.0001987 150 embryonic organ development amigo.geneontol...
GO GO:0001568 View Gene Set 2.287e-06 328 0.000201 151 blood vessel development amigo.geneontol...
GO GO:0051339 View Gene Set 2.281e-06 101 0.000201 151 regulation of lyase activity amigo.geneontol...
GO GO:0045761 View Gene Set 2.306e-06 97 0.0002014 153 regulation of adenylate cyclase activity amigo.geneontol...
GO GO:0005088 View Gene Set 2.462e-06 86 0.0002136 154 Ras guanyl-nucleotide exchange factor activity amigo.geneontol...
GO GO:0051240 View Gene Set 2.524e-06 283 0.0002176 155 positive regulation of multicellular organismal process amigo.geneontol...
GO GO:0015276 View Gene Set 2.701e-06 128 0.0002299 156 ligand-gated ion channel activity amigo.geneontol...
GO GO:0022834 View Gene Set 2.701e-06 128 0.0002299 156 ligand-gated channel activity amigo.geneontol...
GO GO:0060429 View Gene Set 2.769e-06 373 0.0002341 158 epithelium development amigo.geneontol...
GO GO:0015075 View Gene Set 2.897e-06 715 0.0002434 159 ion transmembrane transporter activity amigo.geneontol...
GO GO:0045595 View Gene Set 3.385e-06 563 0.0002827 160 regulation of cell differentiation amigo.geneontol...
GO GO:0048706 View Gene Set 3.573e-06 83 0.0002965 161 embryonic skeletal system development amigo.geneontol...
GO GO:0005179 View Gene Set 3.909e-06 108 0.0003224 162 hormone activity amigo.geneontol...
GO GO:0006811 View Gene Set 3.939e-06 829 0.0003229 163 ion transport amigo.geneontol...
GO GO:0030199 View Gene Set 4.058e-06 27 0.0003306 164 collagen fibril organization amigo.geneontol...
GO GO:0006959 View Gene Set 4.092e-06 85 0.0003313 165 humoral immune response amigo.geneontol...
GO GO:0031589 View Gene Set 4.143e-06 152 0.0003335 166 cell-substrate adhesion amigo.geneontol...
GO GO:0040011 View Gene Set 4.204e-06 617 0.0003363 167 locomotion amigo.geneontol...
GO GO:0010646 View Gene Set 4.413e-06 1173 0.000351 168 regulation of cell communication amigo.geneontol...
GO GO:0007389 View Gene Set 4.892e-06 285 0.0003867 169 pattern specification process amigo.geneontol...
GO GO:0051093 View Gene Set 5e-06 288 0.000393 170 negative regulation of developmental process amigo.geneontol...
GO GO:0005267 View Gene Set 5.095e-06 130 0.0003981 171 potassium channel activity amigo.geneontol...
GO GO:0072001 View Gene Set 5.32e-06 110 0.0004132 172 renal system development amigo.geneontol...
GO GO:0048666 View Gene Set 5.714e-06 399 0.0004412 173 neuron development amigo.geneontol...
GO GO:0042060 View Gene Set 5.782e-06 223 0.000444 174 wound healing amigo.geneontol...
GO GO:0030005 View Gene Set 5.893e-06 250 0.0004499 175 cellular di- tri-valent inorganic cation homeostasis amigo.geneontol...
GO GO:0055080 View Gene Set 6.174e-06 310 0.0004686 176 cation homeostasis amigo.geneontol...
GO GO:0001525 View Gene Set 6.852e-06 236 0.0005172 177 angiogenesis amigo.geneontol...
GO GO:0034703 View Gene Set 7.326e-06 136 0.0005499 178 cation channel complex amigo.geneontol...
GO GO:0032101 View Gene Set 7.737e-06 190 0.0005774 179 regulation of response to external stimulus amigo.geneontol...
GO GO:0045321 View Gene Set 8.122e-06 342 0.0006028 180 leukocyte activation amigo.geneontol...
GO GO:0044456 View Gene Set 9.197e-06 274 0.0006789 181 synapse part amigo.geneontol...
GO GO:0055066 View Gene Set 9.262e-06 264 0.0006799 182 di- tri-valent inorganic cation homeostasis amigo.geneontol...
GO GO:0001822 View Gene Set 9.842e-06 107 0.0007185 183 kidney development amigo.geneontol...
GO GO:0016337 View Gene Set 1.021e-05 318 0.0007416 184 cell-cell adhesion amigo.geneontol...
GO GO:0051216 View Gene Set 1.103e-05 95 0.0007965 185 cartilage development amigo.geneontol...
GO GO:0030003 View Gene Set 1.125e-05 277 0.0008077 186 cellular cation homeostasis amigo.geneontol...
GO GO:0042612 View Gene Set 1.165e-05 22 0.0008323 187 MHC class I protein complex amigo.geneontol...
GO GO:0065008 View Gene Set 1.188e-05 1741 0.0008441 188 regulation of biological quality amigo.geneontol...
GO GO:0007165 View Gene Set 1.201e-05 2232 0.0008493 189 signal transduction amigo.geneontol...
GO GO:0002684 View Gene Set 1.21e-05 274 0.000851 190 positive regulation of immune system process amigo.geneontol...
GO GO:0021953 View Gene Set 1.226e-05 73 0.0008578 191 central nervous system neuron differentiation amigo.geneontol...
GO GO:0033700 View Gene Set 1.245e-05 10 0.0008664 192 phospholipid efflux amigo.geneontol...
GO GO:0048704 View Gene Set 1.327e-05 61 0.0009187 193 embryonic skeletal system morphogenesis amigo.geneontol...
GO GO:0005529 View Gene Set 1.342e-05 196 0.0009242 194 sugar binding amigo.geneontol...
GO GO:0009812 View Gene Set 1.495e-05 10 0.001024 195 flavonoid metabolic process amigo.geneontol...
GO GO:0001654 View Gene Set 1.616e-05 155 0.001102 196 eye development amigo.geneontol...
GO GO:0005583 View Gene Set 1.768e-05 11 0.001199 197 fibrillar collagen amigo.geneontol...
GO GO:0051048 View Gene Set 1.837e-05 70 0.001233 198 negative regulation of secretion amigo.geneontol...
GO GO:0019955 View Gene Set 1.832e-05 113 0.001233 198 cytokine binding amigo.geneontol...
GO GO:0005249 View Gene Set 1.926e-05 97 0.001287 200 voltage-gated potassium channel activity amigo.geneontol...

Gene Set Collection: Broad.c1.CYTOBAND

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad chr19q13 View Gene Set 4.579e-07 765 0.0001493 1 Genes in cytogenetic band chr19q13 www.broad.mit.e...

Gene Set Collection: Broad.c2.CGP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad BENPORATH_ES_WITH_H3K27ME3 View Gene Set 8.036e-62 1094 1.922e-58 1 Set 'H3K27 bound': genes posessing the trimethylated H3K27 (H3K27me3) mark in their promoters in human embryonic stem cells as identified by ChIP on chip. www.broad.mit.e...
Broad BENPORATH_SUZ12_TARGETS View Gene Set 7.499e-46 1011 8.968e-43 2 Set 'Suz12 targets': genes identified by ChIP on chip as targets of the Polycomb protein SUZ12 [Gene ID=23512] in human embryonic stem cells. www.broad.mit.e...
Broad BENPORATH_PRC2_TARGETS View Gene Set 5.811e-40 636 4.634e-37 3 Set 'PRC2 targets': Polycomb Repression Complex 2 (PRC) targets; identified by ChIP on chip on human embryonic stem cells as genes that: posess the trimethylated H3K27 mark in their promoters and are bound by SUZ12 [Gene ID=23512] and EED [Gene ID=8726] Polycomb proteins. www.broad.mit.e...
Broad BENPORATH_EED_TARGETS View Gene Set 8.296e-34 1033 4.961e-31 4 Set 'Eed targets': genes identified by ChIP on chip as targets of the Polycomb protein EED [Gene ID=8726] in human embryonic stem cells. www.broad.mit.e...
Broad LIU_PROSTATE_CANCER_DN View Gene Set 2.027e-28 446 9.696e-26 5 Genes down-regulated in prostate cancer samples. www.broad.mit.e...
Broad SMID_BREAST_CANCER_NORMAL_LIKE_UP View Gene Set 1.695e-27 459 6.758e-25 6 Genes up-regulated in the normal-like subtype of breast cancer. www.broad.mit.e...
Broad SMID_BREAST_CANCER_LUMINAL_B_DN View Gene Set 1.553e-22 549 5.307e-20 7 Genes down-regulated in the luminal B subtype of breast cancer. www.broad.mit.e...
Broad SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 View Gene Set 2.107e-19 407 6.3e-17 8 Genes up-regulated in the pancreatic cancer cell lines (AsPC1 Hs766T MiaPaCa2 Panc1) but not in the non-neoplastic cells (HPDE) by decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. www.broad.mit.e...
Broad DODD_NASOPHARYNGEAL_CARCINOMA_UP View Gene Set 4.273e-19 1582 1.136e-16 9 Genes up-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. www.broad.mit.e...
Broad WALLACE_PROSTATE_CANCER_RACE_UP View Gene Set 4.286e-15 288 1.025e-12 10 Genes up-regulated in prostate cancer samples from African-American patients compared to those from the European-American patients. www.broad.mit.e...
Broad SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP View Gene Set 5.46e-15 339 1.187e-12 11 Genes up-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS non-invasive). www.broad.mit.e...
Broad LINDGREN_BLADDER_CANCER_CLUSTER_2B View Gene Set 1.497e-14 384 2.984e-12 12 Genes specifically up-regulated in Cluster IIb of urothelial cell carcinom (UCC) tumors. www.broad.mit.e...
Broad ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN View Gene Set 2.87e-14 882 5.28e-12 13 Genes whose DNA is hyper-methylated in hepatocellular carcinoma (HCC) compared to normal liver. www.broad.mit.e...
Broad SHEN_SMARCA2_TARGETS_DN View Gene Set 6.696e-14 334 1.144e-11 14 Genes whose expression negatively correlated with that of SMARCA2 [Gene ID=6595] in prostate cancer samples. www.broad.mit.e...
Broad HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP View Gene Set 3.185e-13 399 5.079e-11 15 Genes up-regulated in multiple myeloma (MM) cell lines treated with both decitabine [PubChem=451668] TSA [PubChem=5562]. www.broad.mit.e...
Broad MCLACHLAN_DENTAL_CARIES_DN View Gene Set 2.042e-12 234 3.053e-10 16 Genes down-regulated in pulpal tissue extracted from carious teeth. www.broad.mit.e...
Broad RIGGI_EWING_SARCOMA_PROGENITOR_UP View Gene Set 2.772e-12 399 3.9e-10 17 Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [Gene ID=2130 2321] fusion protein. www.broad.mit.e...
Broad SABATES_COLORECTAL_ADENOMA_DN View Gene Set 6.674e-12 276 8.869e-10 18 Genes down-regulated in colorectal adenoma compared to normal mucosa samples. www.broad.mit.e...
Broad MCLACHLAN_DENTAL_CARIES_UP View Gene Set 3.633e-11 207 4.573e-09 19 Genes up-regulated in pulpal tissue extracted from carious teeth. www.broad.mit.e...
Broad HATADA_METHYLATED_IN_LUNG_CANCER_UP View Gene Set 7.874e-11 355 9.418e-09 20 Genes with hypermethylated DNA in lung cancer samples. www.broad.mit.e...
Broad PEREZ_TP63_TARGETS View Gene Set 1.195e-10 328 1.361e-08 21 Genes up-regulated in the HMEC cells (primary mammary epithelium) upon expression of the transcriptionally active isoform of TP63 [Gene ID=8626] off adenoviral vector. www.broad.mit.e...
Broad MANALO_HYPOXIA_UP View Gene Set 9.974e-10 197 1.062e-07 22 Genes up-regulated in response to both hypoxia and overexpression of an active form of HIF1A [Gene ID=3091]. www.broad.mit.e...
Broad HELLER_HDAC_TARGETS_UP View Gene Set 1.021e-09 268 1.062e-07 22 Genes up-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]. www.broad.mit.e...
Broad ODONNELL_TFRC_TARGETS_UP View Gene Set 1.173e-09 401 1.169e-07 24 Genes up-regulated in P493-6 cells (B lymphocyte) upon knockdown of TFRC [Gene ID=7037] by RNAi. www.broad.mit.e...
Broad VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP View Gene Set 2.368e-09 163 2.266e-07 25 Angiogenic markers up-regulated in lymph endothelial cells upon infection with KSHV (Kaposi's sarcoma herpes virus). www.broad.mit.e...
Broad PEREZ_TP53_TARGETS View Gene Set 3.486e-09 1066 3.207e-07 26 Genes up-regulated in the HMEC cells (primary mammary epithelium) upon expression of TP53 [Gene ID=7157] off adenoviral vector. www.broad.mit.e...
Broad EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP View Gene Set 9.758e-09 201 8.645e-07 27 Genes up-regulated in Rh4 cells (alveolar rhabdomyosarcoma ARMS) after knockdown of the PAX3-FOXO1 [Gene iD=5077 2308] fusion protein by RNAi for 72 hr. www.broad.mit.e...
Broad VERHAAK_AML_WITH_NPM1_MUTATED_DN View Gene Set 2.263e-08 241 1.934e-06 28 Genes down-regulated in acute myeloid leukemia (AML) patients with mutated NPM1 [Gene ID=4869]. www.broad.mit.e...
Broad ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP View Gene Set 6.588e-08 458 5.434e-06 29 Genes up-regulated in macrophage by live P.gingivalis. www.broad.mit.e...
Broad ZHOU_INFLAMMATORY_RESPONSE_LPS_UP View Gene Set 2.601e-07 400 2.074e-05 30 Genes up-regulated in macrophages by P.gingivalis LPS (lipopolysaccharide). www.broad.mit.e...
Broad SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN View Gene Set 2.709e-07 296 2.09e-05 31 Genes down-regulated in nsopharyngeal carcinoma relative to the normal tissue. www.broad.mit.e...
Broad ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP View Gene Set 3.183e-07 502 2.379e-05 32 Genes up-regulated in macrophages by P.gingivalis FimA pathogen. www.broad.mit.e...
Broad SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER View Gene Set 5.825e-07 48 4.222e-05 33 50 most interesting genes up-regulated in pancreatic cancer cell lines (AsPC1 Hs766T MiaPaCa2 Panc1) but not in the non-neoplastic cells (HPDE) by TSA [PubChem=5562]. www.broad.mit.e...
Broad BORCZUK_MALIGNANT_MESOTHELIOMA_DN View Gene Set 6.366e-07 100 4.479e-05 34 Genes down-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma. www.broad.mit.e...
Broad SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP View Gene Set 1.074e-06 157 7.226e-05 35 Genes up-regulated in circulating endothelial cells (CEC) from cancer patients compared to those from healthy donors. www.broad.mit.e...
Broad KONDO_PROSTATE_CANCER_WITH_H3K27ME3 View Gene Set 1.088e-06 187 7.226e-05 35 Top 200 genes with high histone H3 trimethylation mark at K27 (H3K27me3) in PC3 cells (prostate cancer) by ChIP-chip assay on an 88K microarray (all promoters). www.broad.mit.e...
Broad KUNINGER_IGF1_VS_PDGFB_TARGETS_UP View Gene Set 1.372e-06 42 8.869e-05 37 Genes up-regulated in C2AS12 cells (myoblast) by IGF1 [Gene ID=3479] vs PDGFB [Gene ID=5155]. www.broad.mit.e...
Broad ELVIDGE_HYPOXIA_UP View Gene Set 1.962e-06 163 0.0001235 38 Genes up-regulated in MCF7 cells (breast cancer) under hypoxia conditions. www.broad.mit.e...
Broad DELYS_THYROID_CANCER_DN View Gene Set 2.076e-06 213 0.0001273 39 Genes down-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. www.broad.mit.e...
Broad TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN View Gene Set 2.456e-06 186 0.0001433 40 Genes down-regulated in ductal carcinoma vs normal ductal breast cells. www.broad.mit.e...
Broad TARTE_PLASMA_CELL_VS_PLASMABLAST_UP View Gene Set 2.445e-06 386 0.0001433 40 Genes up-regulated in mature plasma cells compared with plasmablastic B lymphocytes. www.broad.mit.e...
Broad GAURNIER_PSMD4_TARGETS View Gene Set 2.832e-06 59 0.0001613 42 Inflammatory cytokines chemokines and their cognate receptors up-regulated in THP-1 cells (monocyte) after treatment with PSMD4 [Gene ID=5710]. www.broad.mit.e...
Broad VECCHI_GASTRIC_CANCER_EARLY_DN View Gene Set 3.076e-06 346 0.0001711 43 Down-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. www.broad.mit.e...
Broad PEREZ_TP53_AND_TP63_TARGETS View Gene Set 3.246e-06 187 0.0001765 44 Genes up-regulated in HMEC cells (primary mammary epithelium) upon expression of both of TP53 [Gene ID=7157] and the transcriptionally active isoform of TP63 [Gene ID=8626] off adenoviral vectors. www.broad.mit.e...
Broad SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER View Gene Set 4.484e-06 86 0.0002384 45 Genes bearing H3K27me3 mark or whose promoters are bound by the polycomb proteins SUZ12 or EED [Gene ID=23512 8726]; their DNA is methylated de novo in cancer. www.broad.mit.e...
Broad MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP View Gene Set 5.14e-06 365 0.0002665 46 Genes distinguishing in multiple myeloma (MM) samples with higher expression of TACI [Gene ID=23495]. www.broad.mit.e...
Broad SENGUPTA_EBNA1_ANTICORRELATED View Gene Set 5.237e-06 156 0.0002665 46 Genes whose reduced expression in nasopharyngeal carinoma (NPC) correlated most with the increased expression of EBNA1 [Gene ID=3783774] a latent gene of Epstein-Barr virus (EBV). www.broad.mit.e...
Broad ELVIDGE_HYPOXIA_BY_DMOG_UP View Gene Set 5.385e-06 125 0.0002684 48 Genes up-regulated in MCF7 cells (breast cancer) treated with hypoxia mimetic DMOG [PubChem=3080614]. www.broad.mit.e...
Broad VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP View Gene Set 5.602e-06 159 0.0002735 49 Up-regulated genes distinguishing between two subtypes of gastric cancer: advanced (AGC) and early (EGC). www.broad.mit.e...
Broad VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN View Gene Set 5.794e-06 134 0.0002772 50 Angiogenic markers down-regulated in lymph endothelial cells upon infection with KSHV (Kaposi's sarcoma herpes virus). www.broad.mit.e...
Broad CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN View Gene Set 6.915e-06 144 0.0003243 51 Top 200 marker genes down-regulated in the 'CTNNB1' subclass of hepatocellular carcinoma (HCC); characterized by activated CTNNB1 [Gene ID=1499]. www.broad.mit.e...
Broad ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP View Gene Set 7.52e-06 178 0.0003459 52 Genes up-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]. www.broad.mit.e...
Broad SENESE_HDAC2_TARGETS_DN View Gene Set 7.796e-06 124 0.0003518 53 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC2 [Gene ID=3066] by RNAi. www.broad.mit.e...
Broad PODAR_RESPONSE_TO_ADAPHOSTIN_UP View Gene Set 1.053e-05 140 0.0004666 54 Up-regulated genes in MM1.S cells (multiple myeloma) treated with adaphostin [PubChem=387042] a tyrosine kinase inhibitor with anticancer properties. www.broad.mit.e...
Broad PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP View Gene Set 1.076e-05 197 0.0004679 55 Up-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes. www.broad.mit.e...
Broad JAATINEN_HEMATOPOIETIC_STEM_CELL_DN View Gene Set 1.191e-05 215 0.0005086 56 Genes up-regulated in CD133+ [Gene ID=8842] cells (hematopoietic stem cells HSC) compared to the CD133- cells. www.broad.mit.e...
Broad NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP View Gene Set 1.281e-05 74 0.0005376 57 Top 100 probe sets contrubuting to the positive side of the 1st principal component; predominantly associated with spindle cell and pleomorphic sarcoma samples. www.broad.mit.e...
Broad MOHANKUMAR_TLX1_TARGETS_DN View Gene Set 1.529e-05 158 0.0006305 58 Down-regulated in MCF7 cells (breast cancer) by TLX1 (HOX11) [Gene ID=3195]. www.broad.mit.e...
Broad HELLER_SILENCED_BY_METHYLATION_UP View Gene Set 1.638e-05 247 0.0006642 59 Genes up-regulated in at least one of three multiple myeloma (MM) cell lines treated with the DNA hypomethylating agent decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. www.broad.mit.e...
Broad CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP View Gene Set 1.923e-05 228 0.0007668 60 Genes up-regulated in SH-SY5Y cells (neuroblastoma) after treatment with epoxomicin [PubChem=3035402] a protease inhibitor causing apoptosis. www.broad.mit.e...
Broad MAHADEVAN_RESPONSE_TO_MP470_DN View Gene Set 2.069e-05 16 0.0008112 61 Top genes up-regulated in the GIST (gastrointestinal stromal tumor) cell line sensitive to imatinib [PubChem=5291] after treatment with MP470 a protein kinase inhibitor. www.broad.mit.e...
Broad YAMASHITA_METHYLATED_IN_PROSTATE_CANCER View Gene Set 2.14e-05 57 0.0008255 62 Genes up-regulated in prostate cancer cell lines after treatment with 5-aza-2'-deoxycytidine (decitabine) [PubChem=451668]. www.broad.mit.e...
Broad DELYS_THYROID_CANCER_UP View Gene Set 2.203e-05 397 0.0008365 63 Genes up-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN View Gene Set 2.295e-05 192 0.0008578 64 Genes down-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 8 days after transduction. www.broad.mit.e...
Broad SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 View Gene Set 2.501e-05 48 0.0009205 65 50 most interesting genes up-regulated in the pancreatic cancer cell lines (AsPC1 Hs766T MiaPaCa2 Panc1) but not in the non-neoplastic cells (HPDE) by decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP View Gene Set 2.96e-05 186 0.001073 66 Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 10 days after transduction. www.broad.mit.e...
Broad TOMLINS_PROSTATE_CANCER_DN View Gene Set 3.185e-05 39 0.001137 67 Genes down-regulated in prostate cancer vs benign prostate tissue based on a meta-analysis of five gene expression profiling studies. www.broad.mit.e...
Broad KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN View Gene Set 3.709e-05 306 0.001305 68 Genes down-regulated in TC71 and EWS502 cells (Ewing's sarcoma) upon knockdown of the EWSR1-FLII fusion [Gene ID=2130 2314]. www.broad.mit.e...
Broad SWEET_LUNG_CANCER_KRAS_DN View Gene Set 3.991e-05 397 0.001374 69 Genes down-regulated in the mouse lung cancer model with mutated KRAS [Gene ID=3845]. www.broad.mit.e...
Broad CROONQUIST_STROMAL_STIMULATION_UP View Gene Set 4.022e-05 47 0.001374 69 Genes up-regulated in ANBL-6 cell line (multiple myeloma MM) co-cultured with bone marrow stromal cells compared to those grown in the presence of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad LEE_NEURAL_CREST_STEM_CELL_DN View Gene Set 4.207e-05 114 0.001417 71 Genes down-regulated in the neural crest stem cells (NCS) defined as p75+/HNK1+ [Gene ID=4804 27087]. www.broad.mit.e...
Broad NAGASHIMA_EGF_SIGNALING_UP View Gene Set 4.753e-05 57 0.001567 72 Genes up-regulated in MCF7 cells (breast cancer) after stimulation with EGF [Gene ID=1950]. www.broad.mit.e...
Broad HUPER_BREAST_BASAL_VS_LUMINAL_UP View Gene Set 4.782e-05 54 0.001567 72 Genes up-regulated in basal mammary epithelial cells compared to the luminal ones. www.broad.mit.e...
Broad GOZGIT_ESR1_TARGETS_DN View Gene Set 5.955e-05 710 0.001899 74 Genes down-regulated in TMX2-28 cells (breast cancer) which do not express ESR1 [Gene ID=2099]) compared to the parental MCF7 cells which do. www.broad.mit.e...
Broad CROMER_TUMORIGENESIS_DN View Gene Set 5.904e-05 43 0.001899 74 Tumorigenesis markers of head and neck squamous cell carcinoma (HNSCC): down-regulated in the 'early' tumors vs normal samples. www.broad.mit.e...
Broad HOOI_ST7_TARGETS_DN View Gene Set 6.131e-05 108 0.00193 76 Genes down-regulated in PC-3 cells (prostate cancer) stably expressing ST7 [Gene ID=7982] off a plasmid vector. www.broad.mit.e...
Broad TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN View Gene Set 6.515e-05 64 0.002024 77 Genes down-regulated in ductal carcinoma vs normal lobular breast cells. www.broad.mit.e...
Broad ELVIDGE_HIF1A_TARGETS_DN View Gene Set 7.914e-05 87 0.002427 78 Genes down-regulated in MCF7 cells (breast cancer) after knockdown of HIF1A [Gene ID=3091] by RNAi. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN View Gene Set 9.028e-05 138 0.002733 79 Genes down-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 10 days after transduction. www.broad.mit.e...
Broad SHIPP_DLBCL_CURED_VS_FATAL_UP View Gene Set 9.584e-05 38 0.002865 80 Top 50 up-regulated markers for the diffused large B-cell lymphoma (DLBCL) that distinguished between cured and fatal/refractory clinical outcomes. www.broad.mit.e...
Broad HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP View Gene Set 0.0001161 34 0.003428 81 Genes up-regulated in SCLC (small cell lung cancer) cells with acquired resistance to ABT-737 [PubChem=11228183] an inhibitor of the BCL2 [Gene ID=596] family proteins. www.broad.mit.e...
Broad WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN View Gene Set 0.0001196 23 0.003448 82 Down-regulated genes characteristic for autonomous thyroid adenoma. www.broad.mit.e...
Broad KHETCHOUMIAN_TRIM24_TARGETS_UP View Gene Set 0.0001196 45 0.003448 82 Retinoic acid-responsive genes up-regulated in hepatocellular carcinoma (HCC) samples of TRIM24 [Gene ID=8805] knockout mice. www.broad.mit.e...
Broad WANG_SMARCE1_TARGETS_UP View Gene Set 0.0001391 158 0.003962 84 Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [Gene ID=6605] off a retroviral vector. www.broad.mit.e...
Broad GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP View Gene Set 0.0001432 75 0.004029 85 Up-regulated genes from the set E (Fig. 5a): specific signature shared by cells expressing either MLL-AF4 [Gene ID=4297 4299] or AF4-MLL fusion proteins alone and those expressing both fusion proteins. www.broad.mit.e...
Broad RICKMAN_HEAD_AND_NECK_CANCER_A View Gene Set 0.0001506 91 0.00419 86 Cluster a: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). www.broad.mit.e...
Broad CERVERA_SDHB_TARGETS_1_UP View Gene Set 0.0001578 110 0.004338 87 Genes turned on in Hep3B cells (hepatocellular carcinoma HCC) upon knockdown of SDHB [Gene ID=6390] by RNAi. www.broad.mit.e...
Broad RICKMAN_HEAD_AND_NECK_CANCER_D View Gene Set 0.0001624 36 0.004413 88 Cluster d: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). www.broad.mit.e...
Broad WANG_METHYLATED_IN_BREAST_CANCER View Gene Set 0.000168 32 0.004515 89 Genes up-regulated in MDA468 cells (breast cancer) vs DU99 cells (normal breast) after treatment with azacytidine [PubChem=9444]. www.broad.mit.e...
Broad MCGARVEY_SILENCED_BY_METHYLATION_IN_COLON_CANCER View Gene Set 0.0001815 42 0.004825 90 Genes silenced in HCT116 cells (colon cancer) by methylation of CpG islands in their promoters. www.broad.mit.e...
Broad NAKAMURA_CANCER_MICROENVIRONMENT_UP View Gene Set 0.0001888 25 0.004857 91 Genes up-regulated in pancreatic cancer cells grown in orthotopic xenograft tumors compared to those grown in vitro. www.broad.mit.e...
Broad CHEBOTAEV_GR_TARGETS_DN View Gene Set 0.000186 118 0.004857 91 Genes down-regulated in follicular epithelial stem cells after transgenic expression of GR [Gene ID=2908] under control of the keratin5 (K5) [Gene ID=3852] promoter. www.broad.mit.e...
Broad WILENSKY_RESPONSE_TO_DARAPLADIB View Gene Set 0.0001868 27 0.004857 91 Atherosclerotic process genes whose coronary expression changed after darapladib [PubChem=9939609] treatment. www.broad.mit.e...
Broad AMIT_DELAYED_EARLY_GENES View Gene Set 0.0002092 17 0.005323 94 Delayed early genes (DEG) which are coordinately down-regulated in multiple epithelial tumor types. www.broad.mit.e...
Broad WONG_ENDMETRIUM_CANCER_DN View Gene Set 0.0002211 42 0.005567 95 Genes down-regulated in cancer endometrium samples compared to the normal endometrium. www.broad.mit.e...
Broad KERLEY_RESPONSE_TO_CISPLATIN_UP View Gene Set 0.0002274 38 0.005666 96 Genes genes up-regulated in NT2/D1 cells (embryonal carcinoma) in response to treatment with cisplatin [PubChem=2767]. www.broad.mit.e...
Broad ROZANOV_MMP14_TARGETS_SUBSET View Gene Set 0.0002365 33 0.005831 97 Genes linked to the ECM maintenance and angiogenesis that were changed in HT1080 cells (fibrosarcoma) over-expressing MMP14 [Gene ID=4323] compared to those with knockdown of the gene by RNAi. www.broad.mit.e...
Broad SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN View Gene Set 0.0002403 167 0.005865 98 Genes down-regulated in nasopharyngeal carcinoma (NPC) positive for LMP1 [Gene ID=9260] a latent gene of Epstein-Barr virus (EBV). www.broad.mit.e...
Broad ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN View Gene Set 0.0003333 100 0.008053 99 Genes down-regulated in MCF7 cells (breast cancer) after knockdown of both HIF1A and HIF2A [Gene ID=3091 2034] by RNAi. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP View Gene Set 0.0003428 174 0.008199 100 Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 3 days after transduction. www.broad.mit.e...
Broad MUELLER_METHYLATED_IN_GLIOBLASTOMA View Gene Set 0.0003546 42 0.008371 101 Genes up-regulated in short-term cultured glioblastomas after azacitidine [PubChem=9444] treatment. www.broad.mit.e...
Broad COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP View Gene Set 0.0003569 34 0.008371 101 Genes up-regulated in pilocytic astrocytoma compared to glioblastoma samples. www.broad.mit.e...
Broad ODONNELL_METASTASIS_UP View Gene Set 0.000411 77 0.009418 103 Up-regulated genes in the signature set for lymph node metastasis in head and neck squamous cell carcinoma (HNSCC). www.broad.mit.e...
Broad RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP View Gene Set 0.0004084 25 0.009418 103 ES/PNET (Ewing sarcoma; primitive neuroectodermal tumors) markers up-regulated in neuroblastoma cell lines expressing ESWR1-FLI1 [Gene ID=2130 2313] fusion protein. www.broad.mit.e...
Broad TAVAZOIE_METASTASIS View Gene Set 0.0004134 103 0.009418 103 Putative metastasis genes: up-regulated in metastatic cell lines LM2 (lung) and BoM2 (bone) relative to the parental MDA-MB-231 line (breast adenocarcinoma). www.broad.mit.e...
Broad MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP View Gene Set 0.000418 22 0.009432 106 Top genes up-regulated in mesenchyme stem cells (MSC) grown in a tumor conditioned medium which leads to carcinoma-associated fibroblast phenotype. www.broad.mit.e...
Broad CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 View Gene Set 0.0004527 377 0.01003 107 The 'group 2 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [Gene ID=2099 2064]. www.broad.mit.e...
Broad HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS View Gene Set 0.0004501 56 0.01003 107 Genes down-regulated in tumor-conditioned vs quiescent endothelial cells and up-regulated upon treatment with decitabine and TSA [PubChem=451668 5562]. www.broad.mit.e...
Broad NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN View Gene Set 0.0004595 78 0.01008 109 Top 100 probe sets contrubuting to the negative side of the 2nd principal component; associated with adipocytic differentiation. www.broad.mit.e...
Broad FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP View Gene Set 0.0004696 86 0.01021 110 Genes differentially expressed in kidney biopsies from patients with acute transplant rejection compared to the biopsies from patients with well functioning kidneys more than 1-year post transplant. www.broad.mit.e...
Broad RICKMAN_HEAD_AND_NECK_CANCER_C View Gene Set 0.0004949 107 0.01066 111 Cluster c: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). www.broad.mit.e...
Broad LOPES_METHYLATED_IN_COLON_CANCER_UP View Gene Set 0.0005051 23 0.01079 112 Genes methylated aberrantly in HCT116 and Colo320 (colon cancer) cells. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP View Gene Set 0.0006304 168 0.01334 113 Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 16 days after transduction. www.broad.mit.e...
Broad OSADA_ASCL1_TARGETS_UP View Gene Set 0.0006413 46 0.01346 114 Genes up-regulated in A549 cells (lung cancer) upon expression of ASCL1 [Gene ID=429] off a viral vector. www.broad.mit.e...
Broad BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN View Gene Set 0.0006559 153 0.01364 115 Genes down-regulated in medullary breast cancer (MBC) relative to ductal breast cancer (DBD). www.broad.mit.e...
Broad CROMER_TUMORIGENESIS_UP View Gene Set 0.0006831 43 0.01409 116 Tumorigenesis markers of head and neck squamous cell carcinoma (HNSCC): up-regulated in the 'early' tumors vs normal samples. www.broad.mit.e...
Broad KOBAYASHI_RESPONSE_TO_ROMIDEPSIN View Gene Set 0.0007103 19 0.01452 117 Genes up-regulated in MM-LH cells (malignant melanoma) after treatment with the HDAC inhibitor romidepsin (FK228) [PubChem=5352062]. www.broad.mit.e...
Broad REN_ALVEOLAR_RHABDOMYOSARCOMA_UP View Gene Set 0.0007186 95 0.01457 118 Genes commonly up-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [Gene ID=5077 2308] fusion. www.broad.mit.e...
Broad CHEN_HOXA5_TARGETS_6HR_UP View Gene Set 0.0008155 10 0.01639 119 Differentially expressed genes 6 hr after tinduction of HoxA5 [Gene ID=3205] expression in a breast cancer cell line. www.broad.mit.e...
Broad SENESE_HDAC1_AND_HDAC2_TARGETS_DN View Gene Set 0.0008523 218 0.01684 120 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of both HDAC1 and HDAC2 [Gene ID=3065 3066] by RNAi. www.broad.mit.e...
Broad LEE_NEURAL_CREST_STEM_CELL_UP View Gene Set 0.0008487 142 0.01684 120 Genes up-regulated in the neural crest stem cells (NCS) defined as p75+/HNK1+ [Gene ID=4804 27087]. www.broad.mit.e...
Broad SANA_RESPONSE_TO_IFNG_UP View Gene Set 0.0008633 68 0.01684 120 Genes up-regulated in five primary endothelial cell types (lung aortic iliac dermal and colon) by IFNG [Gene ID=3458]. www.broad.mit.e...
Broad VERHAAK_AML_WITH_NPM1_MUTATED_UP View Gene Set 0.0008688 178 0.01684 120 Genes up-regulated in acute myeloid leukemia (AML) patients with mutated NPM1 [Gene ID=4869]. www.broad.mit.e...
Broad MILICIC_FAMILIAL_ADENOMATOUS_POLYPOSIS_DN View Gene Set 0.000873 10 0.01684 120 Top genes down-regulated in colon epithelium biopsies from FAP (familial adenomatous polyposis) patients with mutated APC [Gene ID=324]. www.broad.mit.e...
Broad VALK_AML_WITH_11Q23_REARRANGED View Gene Set 0.0009357 18 0.01791 125 Genes that best predicted acute myeloid leukemia (AML) with the 11q23 rearrangements. www.broad.mit.e...
Broad SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER View Gene Set 0.0009793 46 0.01859 126 50 genes up-regulated in the pancreatic cancer cell lines (AsPC1 Hs766T MiaPaCa2 Panc1) but not in the non-neoplastic cells (HPDE) by the combination of decitabine and TSA [PubChem=451668 5562]. www.broad.mit.e...
Broad HUANG_FOXA2_TARGETS_DN View Gene Set 0.001021 36 0.01908 127 Genes down-regulated in H358 cells (lung cancer) by inducible expression of FOXA2 [GeneID=3170] in a Tet-off system. www.broad.mit.e...
Broad SMID_BREAST_CANCER_LUMINAL_A_UP View Gene Set 0.001018 79 0.01908 127 Genes up-regulated in the luminal A subtype of breast cancer. www.broad.mit.e...
Broad KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN View Gene Set 0.001108 56 0.02054 129 Genes down-regulated in AIDS-related primary effusion lymphoma (PEL) samples compared to other tumor subtypes and normal B lymphocytes. www.broad.mit.e...
Broad KAN_RESPONSE_TO_ARSENIC_TRIOXIDE View Gene Set 0.001126 117 0.02072 130 Genes changed in U373-MG cells (malignant glioma) upon treatment with arsenic trioxide [PubChem=14888] a chemical that can cause autophagic cell death. www.broad.mit.e...
Broad YU_MYC_TARGETS_DN View Gene Set 0.00116 44 0.02118 131 Genes down-regulated in B cell lymphoma tumors expressing an activated form of MYC [Gene ID=4609]. www.broad.mit.e...
Broad ROY_WOUND_BLOOD_VESSEL_UP View Gene Set 0.001182 48 0.02118 132 Genes up-regulated in blood vessel cells from wound site. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP View Gene Set 0.001188 153 0.02118 132 Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 8 days after transduction. www.broad.mit.e...
Broad SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 View Gene Set 0.001189 296 0.02118 132 Cluster 12 of method A: up-regulation of these genes in patients with non-small cell lung cancer (NSCLC) predicts good survival outcome. www.broad.mit.e...
Broad LIU_VAV3_PROSTATE_CARCINOGENESIS_UP View Gene Set 0.001196 89 0.02118 132 Selected genes up-regulated in prostate tumors developed by transgenic mice overexpressing VAV3 [Gene ID=10451] in prostate epithelium. www.broad.mit.e...
Broad CAIRO_HEPATOBLASTOMA_CLASSES_DN View Gene Set 0.001207 205 0.02124 136 Genes down-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). www.broad.mit.e...
Broad RIGGINS_TAMOXIFEN_RESISTANCE_UP View Gene Set 0.001307 65 0.02282 137 Genes up-regulated SUM44/LCCTam cells (breast cancer) resistant to 4-hydroxytamoxifen [PubChem=63062] relative to the parental SUM44 cells sensitive to the drug. www.broad.mit.e...
Broad EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION View Gene Set 0.001357 50 0.02352 138 Muscle development genes up-regulated in Rh4 cells (alveolar rhabdomyosarcoma ARMS) but not in the RD cells (embryonal rhabdomyosarcoma ERMS) after knockdown of PAX3-FOXO1 [Gene ID=5077 2308] fusion by RNAi for 72 hr. www.broad.mit.e...
Broad HATADA_METHYLATED_IN_LUNG_CANCER_DN View Gene Set 0.001419 29 0.02441 139 Genes with unmethylated DNA in lung cancer samples. www.broad.mit.e...
Broad VALK_AML_CLUSTER_13 View Gene Set 0.001518 27 0.02594 140 Top 40 genes from cluster 13 of acute myeloid leukemia (AML) expression profile; 91% of the samples are FAB M2 subtype all bear the t(8;21) translocation producing the AML1-ETO fusion [Gene ID=861 862]; indicate good survival. www.broad.mit.e...
Broad FARMER_BREAST_CANCER_CLUSTER_5 View Gene Set 0.00153 19 0.02596 141 Cluster 5: selected 17q21_23 amplicon genes clustered together across breast cancer samples. www.broad.mit.e...
Broad AMIT_EGF_RESPONSE_20_HELA View Gene Set 0.001577 11 0.02657 142 Genes whose expression peaked at 20 min after stimulation of HeLa cells with EGF [Gene ID=1950]. www.broad.mit.e...
Broad ENGELMANN_CANCER_PROGENITORS_DN View Gene Set 0.001754 69 0.02935 143 Down-regulated genes in the cancer progenitor (stem) cells corresponding to side population (SP) MCF7 cells (breast cancer) positive for MUC1 [Gene ID=4582]. www.broad.mit.e...
Broad FURUKAWA_DUSP6_TARGETS_PCI35_UP View Gene Set 0.001771 64 0.02942 144 Genes up-regulated in PCI-35 cells (pancreatic cancer lack endogenous DUSP6 [Gene ID=1848]) upon expression of DUSP6 off an adenoviral vector. www.broad.mit.e...
Broad SUH_COEXPRESSED_WITH_ID1_AND_ID2_UP View Gene Set 0.00179 18 0.02952 145 Genes whose expression positively correlates with that of both ID1 [Gene ID=3397] and ID2 [Gene ID=3398] genes in a cohort of 285 patients with primaly AML (acule myelogenous leukemia) [PMID=15084694]. www.broad.mit.e...
Broad MURATA_VIRULENCE_OF_H_PILORI View Gene Set 0.001886 16 0.03053 146 Selected genes up-regulated in WT-A10 cells (gastric epithelium) expressing the H. pilori virulence gene CagA. www.broad.mit.e...
Broad BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN View Gene Set 0.00187 30 0.03053 146 Genes down-regulated in cultured stromal stem cells from adipose tissue compared to the freshly isolated cells. www.broad.mit.e...
Broad HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_UP View Gene Set 0.001889 21 0.03053 146 Genes up-regulated in bone marrow hematopoietic stem cells (HSC CD34+ [Gene ID=947]) from patients with low risk of myelodysplastic syndrome (MDS) compared with healthy controls. www.broad.mit.e...
Broad JAEGER_METASTASIS_DN View Gene Set 0.001933 252 0.03083 149 Genes down-regulated in metastases from malignant melanoma compared to the primary tumors. www.broad.mit.e...
Broad BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN View Gene Set 0.001928 45 0.03083 149 Genes down-regulated in the invasive ductal carcinoma (IDC) compared to the invasive lobular carcinoma (ILC) the two major pathological types of breast cancer. www.broad.mit.e...
Broad SABATES_COLORECTAL_ADENOMA_UP View Gene Set 0.001967 132 0.03086 151 Genes up-regulated in colorectal adenoma compared to normal mucosa samples. www.broad.mit.e...
Broad CADWELL_ATG16L1_TARGETS_UP View Gene Set 0.001974 83 0.03086 151 Genes up-regulated in Paneth cell (part of intestiinal epithelium) of mice with hypomorphic (reduced function) form of ATG16L1 [Gene ID=55054]. www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_30MIN_UP View Gene Set 0.001969 53 0.03086 151 Genes up-regulated in primary fibroblast cell culture at 30 min time point after infection with HCMV (AD169 strain). www.broad.mit.e...
Broad BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN View Gene Set 0.002045 138 0.03177 154 Genes down-regulated in T98G cells (glioma express MGMT [Gene ID=4255]) by carmustine [PubChem=2578] at 48 h. www.broad.mit.e...
Broad DOANE_BREAST_CANCER_ESR1_DN View Gene Set 0.002069 48 0.03193 155 Genes changed in breast cancer samples according to the ESR1 [Gene ID=2099] status: ER positive vs ER negative tumors. www.broad.mit.e...
Broad IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN View Gene Set 0.002108 104 0.03218 156 Genes down-regulated in adipose tissue mesenchymal stem cells (ASC) vs bone marrow mesenchymal stem cells (rBMSC) www.broad.mit.e...
Broad BRUECKNER_TARGETS_OF_MIRLET7A3_DN View Gene Set 0.002112 77 0.03218 156 Genes down-regulated in A549 cells (lung cancer) expressing MIRLET7A3 [Gene ID=406883] microRNA off a plasmid vector. www.broad.mit.e...
Broad WINTER_HYPOXIA_DN View Gene Set 0.002233 46 0.03381 158 Genes down-regulated in head and neck tumor samples which clustered around known hypoxia genes. www.broad.mit.e...
Broad ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP View Gene Set 0.002254 208 0.0339 159 Genes up-regulated in BxPC3 cells (pancreatic cancer) after treatment with TNF [Gene ID=7124] or IKI-1 an inhibitor of I?B kinase (IKK). www.broad.mit.e...
Broad BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN View Gene Set 0.002337 36 0.03494 160 Genes down-regulated in SaOS-2 cells (osteosarcoma) upon expression of PAX3-FOXO1 [Gene ID=5077 2308] fusion protein off an adenoviral vector. www.broad.mit.e...
Broad HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP View Gene Set 0.002498 64 0.03706 161 Genes up-regulated in T helper cells (defines as CD4+) isolated from patients with mucosis fungoides compared to those from normal control donors. www.broad.mit.e...
Broad GAUTSCHI_SRC_SIGNALING View Gene Set 0.00251 8 0.03706 161 Genes down-regulated in A549 cells (lung cancer) after treatment with AZD0530 [PubChem=10302451] a SRC [Gene ID=6714] kinase inhibitor. www.broad.mit.e...
Broad SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_DN View Gene Set 0.002575 35 0.03779 163 Selected genes down-regulated in peripheral blood monocytes (PBMC) of patients with hepatocellular carcinoma (HCC) compared to those with chronic hepatitis. www.broad.mit.e...
Broad LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT View Gene Set 0.002654 100 0.0385 164 Genes downregulated in MCF10A cells (breast cancer) co-cultured with cancer-associated fibroblasts (CAF). www.broad.mit.e...
Broad SANA_TNF_SIGNALING_UP View Gene Set 0.002656 75 0.0385 164 Genes up-regulated in five primary endothelial cell types (lung aortic iliac dermal and colon) by TNF [Gene ID=7124]. www.broad.mit.e...
Broad RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP View Gene Set 0.0027 75 0.03891 166 Genes up-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids. www.broad.mit.e...
Broad TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP View Gene Set 0.002779 155 0.03956 167 Genes up-regulated in erythroid lineage cells by RUNX1-RUNX1T1 [Gene ID=861 862] fusion . www.broad.mit.e...
Broad BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_UP View Gene Set 0.002774 18 0.03956 167 Genes up-regulated in NIH3T3 cells (fibroblasts) transfrormed by expression of constitutively active (Q63L) form of RHOA [Gene ID=387] off plasmid vector; their expression did NOT reverted completely after treatment with Y27632 [PubChem=123862] an inhibitor of ROCK proteins. www.broad.mit.e...
Broad GOZGIT_ESR1_TARGETS_UP View Gene Set 0.002843 141 0.04006 169 Genes up-regulated in TMX2-28 cells (breast cancer) which do not express ESR1 [Gene ID=2099]) compared to the parental MCF7 cells which do. www.broad.mit.e...
Broad WONG_ENDOMETRIAL_CANCER_LATE View Gene Set 0.002847 9 0.04006 169 Genes down-regulated in late stage (stage 3) endometrial cancers compared to the earlier stages (stage 1 and 2). www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 View Gene Set 0.002923 67 0.04089 171 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 1. www.broad.mit.e...
Broad RICKMAN_HEAD_AND_NECK_CANCER_E View Gene Set 0.003018 83 0.04198 172 Cluster e: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). www.broad.mit.e...
Broad FARMER_BREAST_CANCER_CLUSTER_1 View Gene Set 0.003077 44 0.04255 173 Cluster 1: interferon T and B lymphocyte genes clustered together across breast cancer samples. www.broad.mit.e...
Broad FOURNIER_ACINAR_DEVELOPMENT_LATE_UP View Gene Set 0.003113 10 0.04256 174 Genes up-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro. www.broad.mit.e...
Broad WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_DN View Gene Set 0.003114 34 0.04256 174 Genes down-regulated in esophageal adenocarcinoma (EAC) and Barret's esophagus (BE) relative to normal esophagi. www.broad.mit.e...
Broad SENESE_HDAC1_TARGETS_DN View Gene Set 0.003204 235 0.04354 176 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [Gene ID=3065] by RNAi. www.broad.mit.e...
Broad LY_AGING_MIDDLE_UP View Gene Set 0.003262 13 0.04409 177 Genes up-regulated in fibroblasts from middle-age individuals compared to those from the young donors. www.broad.mit.e...
Broad KOBAYASHI_EGFR_SIGNALING_6HR_DN View Gene Set 0.003418 18 0.04593 178 Genes down-regulated in H1975 cells (non-small cell lung cancer NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 6h. www.broad.mit.e...
Broad MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN View Gene Set 0.003457 76 0.04594 179 Genes down-regulated in apoptotic tissues (neuroepithelium) after MDM4 [Gene ID=4194] knockout. www.broad.mit.e...
Broad JEON_SMAD6_TARGETS_UP View Gene Set 0.003457 23 0.04594 179 Genes up-regulated in H1299 cells (lung cancer) upon knockdown of SMAD6 [Gene ID=4091] by RNAi. www.broad.mit.e...
Broad FERRANDO_TAL1_NEIGHBORS View Gene Set 0.003574 17 0.04723 181 Nearest neighbors of TAL1 [Gene ID=6886] based on the close agreement of their expression profiles with that of TAL1 in pediatric T cell acute lymphoblastic leukemia (T-ALL) www.broad.mit.e...
Broad NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN View Gene Set 0.003612 73 0.04747 182 Top 100 probe sets contrubuting to the negative side of the 1st principal component; predominantly associated with synovial sarcoma and myxoid/round cell liposarcoma samples. www.broad.mit.e...
Broad RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_DN View Gene Set 0.003633 21 0.04749 183 Neuroblastoma markers down-regulated in neuroblastoma cell lines expressing ESWR1-FLI1 [Gene ID=2130 2313] fusion protein. www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.BIOCARTA

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad BIOCARTA_COMP_PATHWAY View Gene Set 0.0009058 19 0.03931 1 Complement Pathway www.broad.mit.e...
Broad BIOCARTA_IL17_PATHWAY View Gene Set 0.0007574 17 0.03931 1 IL 17 Signaling Pathway www.broad.mit.e...
Broad BIOCARTA_TCRA_PATHWAY View Gene Set 0.0002558 13 0.03931 1 Lck and Fyn tyrosine kinases in initiation of TCR Activation www.broad.mit.e...
Broad BIOCARTA_TCYTOTOXIC_PATHWAY View Gene Set 0.0005024 14 0.03931 1 T Cytotoxic Cell Surface Molecules www.broad.mit.e...
Broad BIOCARTA_THELPER_PATHWAY View Gene Set 0.0008351 14 0.03931 1 T Helper Cell Surface Molecules www.broad.mit.e...
Broad BIOCARTA_NO2IL12_PATHWAY View Gene Set 0.001124 17 0.04066 6 NO2-dependent IL 12 Pathway in NK cells www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.KEGG

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION View Gene Set 1.096e-10 272 2.039e-08 1 Neuroactive ligand-receptor interaction www.broad.mit.e...
Broad KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION View Gene Set 6.796e-09 267 6.32e-07 2 Cytokine-cytokine receptor interaction www.broad.mit.e...
Broad KEGG_CELL_ADHESION_MOLECULES_CAMS View Gene Set 1.713e-07 134 9.119e-06 3 Cell adhesion molecules (CAMs) www.broad.mit.e...
Broad KEGG_OLFACTORY_TRANSDUCTION View Gene Set 1.961e-07 389 9.119e-06 3 Olfactory transduction www.broad.mit.e...
Broad KEGG_GRAFT_VERSUS_HOST_DISEASE View Gene Set 8.62e-07 42 3.207e-05 5 Graft-versus-host disease www.broad.mit.e...
Broad KEGG_AUTOIMMUNE_THYROID_DISEASE View Gene Set 1.763e-06 53 5.464e-05 6 Autoimmune thyroid disease www.broad.mit.e...
Broad KEGG_ALLOGRAFT_REJECTION View Gene Set 2.595e-06 38 6.895e-05 7 Allograft rejection www.broad.mit.e...
Broad KEGG_ECM_RECEPTOR_INTERACTION View Gene Set 3.774e-06 84 8.775e-05 8 ECM-receptor interaction www.broad.mit.e...
Broad KEGG_TYPE_I_DIABETES_MELLITUS View Gene Set 9.064e-06 44 0.0001873 9 Type I diabetes mellitus www.broad.mit.e...
Broad KEGG_COMPLEMENT_AND_COAGULATION_CASCADES View Gene Set 2.108e-05 69 0.0003922 10 Complement and coagulation cascades www.broad.mit.e...
Broad KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450 View Gene Set 3.04e-05 70 0.0005141 11 Metabolism of xenobiotics by cytochrome P450 www.broad.mit.e...
Broad KEGG_STEROID_HORMONE_BIOSYNTHESIS View Gene Set 0.0001001 55 0.001552 12 Steroid hormone biosynthesis www.broad.mit.e...
Broad KEGG_HEMATOPOIETIC_CELL_LINEAGE View Gene Set 0.0001354 88 0.001937 13 Hematopoietic cell lineage www.broad.mit.e...
Broad KEGG_CALCIUM_SIGNALING_PATHWAY View Gene Set 0.0001761 178 0.002339 14 Calcium signaling pathway www.broad.mit.e...
Broad KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG View Gene Set 0.000433 25 0.005369 15 Maturity onset diabetes of the young www.broad.mit.e...
Broad KEGG_DRUG_METABOLISM_CYTOCHROME_P450 View Gene Set 0.0005058 72 0.00588 16 Drug metabolism - cytochrome P450 www.broad.mit.e...
Broad KEGG_LINOLEIC_ACID_METABOLISM View Gene Set 0.001015 29 0.01111 17 Linoleic acid metabolism www.broad.mit.e...
Broad KEGG_TASTE_TRANSDUCTION View Gene Set 0.001341 52 0.01385 18 Taste transduction www.broad.mit.e...
Broad KEGG_RETINOL_METABOLISM View Gene Set 0.001478 64 0.01447 19 Retinol metabolism www.broad.mit.e...
Broad KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION View Gene Set 0.001757 48 0.01634 20 Intestinal immune network for IgA production www.broad.mit.e...
Broad KEGG_ASCORBATE_AND_ALDARATE_METABOLISM View Gene Set 0.002178 25 0.01929 21 Ascorbate and aldarate metabolism www.broad.mit.e...
Broad KEGG_ARACHIDONIC_ACID_METABOLISM View Gene Set 0.002696 58 0.0228 22 Arachidonic acid metabolism www.broad.mit.e...
Broad KEGG_STARCH_AND_SUCROSE_METABOLISM View Gene Set 0.003593 52 0.02906 23 Starch and sucrose metabolism www.broad.mit.e...
Broad KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS View Gene Set 0.004781 28 0.03705 24 Pentose and glucuronate interconversions www.broad.mit.e...
Broad KEGG_DILATED_CARDIOMYOPATHY View Gene Set 0.005316 92 0.03955 25 Dilated cardiomyopathy www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.REACTOME

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad REACTOME_GPCR_LIGAND_BINDING View Gene Set 2.491e-13 392 1.071e-10 1 Genes involved in GPCR ligand binding www.broad.mit.e...
Broad REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING View Gene Set 6.232e-13 448 1.34e-10 2 Genes involved in Downstream events in GPCR signaling www.broad.mit.e...
Broad REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS View Gene Set 4.871e-10 292 6.982e-08 3 Genes involved in Class A/1 (Rhodopsin-like receptors) www.broad.mit.e...
Broad REACTOME_OLFACTORY_SIGNALING_PATHWAY View Gene Set 1.417e-07 371 1.523e-05 4 Genes involved in Olfactory Signaling Pathway www.broad.mit.e...
Broad REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS View Gene Set 1.89e-07 173 1.625e-05 5 Genes involved in Peptide ligand-binding receptors www.broad.mit.e...
Broad REACTOME_NCAM1_INTERACTIONS View Gene Set 4.016e-06 43 0.0002878 6 Genes involved in NCAM1 interactions www.broad.mit.e...
Broad REACTOME_G_ALPHA_I_SIGNALLING_EVENTS View Gene Set 1.383e-05 177 0.0008496 7 Genes involved in G alpha (i) signalling events www.broad.mit.e...
Broad REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES View Gene Set 4.993e-05 37 0.002684 8 Genes involved in Generation of second messenger molecules www.broad.mit.e...
Broad REACTOME_TRANSLOCATION_OF_ZAP70_TO_IMMUNOLOGICAL_SYNAPSE View Gene Set 6.235e-05 24 0.002979 9 Genes involved in Translocation of ZAP-70 to Immunological synapse www.broad.mit.e...
Broad REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS View Gene Set 8.554e-05 156 0.003678 10 Genes involved in G alpha (q) signalling events www.broad.mit.e...
Broad REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE View Gene Set 9.622e-05 49 0.003762 11 Genes involved in Cytochrome P450 - arranged by substrate type www.broad.mit.e...
Broad REACTOME_G_ALPHA_S_SIGNALLING_EVENTS View Gene Set 0.0001101 126 0.003946 12 Genes involved in G alpha (s) signalling events www.broad.mit.e...
Broad REACTOME_BIOLOGICAL_OXIDATIONS View Gene Set 0.000129 127 0.004266 13 Genes involved in Biological oxidations www.broad.mit.e...
Broad REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL View Gene Set 0.0001735 106 0.005329 14 Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell www.broad.mit.e...
Broad REACTOME_GAP_JUNCTION_ASSEMBLY View Gene Set 0.0002989 19 0.008569 15 Genes involved in Gap junction assembly www.broad.mit.e...
Broad REACTOME_AMINE_DERIVED_HORMONES View Gene Set 0.0004004 13 0.01073 16 Genes involved in Amine-derived hormones www.broad.mit.e...
Broad REACTOME_GLUCURONIDATION View Gene Set 0.0004244 19 0.01073 16 Genes involved in Glucuronidation www.broad.mit.e...
Broad REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS View Gene Set 0.0005046 26 0.01205 18 Genes involved in Phosphorylation of CD3 and TCR zeta chains www.broad.mit.e...
Broad REACTOME_CLASS_B2_SECRETIN_FAMILY_RECEPTORS View Gene Set 0.0007448 85 0.01686 19 Genes involved in Class B/2 (Secretin family receptors) www.broad.mit.e...
Broad REACTOME_CRMPS_IN_SEMA3A_SIGNALING View Gene Set 0.0008331 16 0.01791 20 Genes involved in CRMPs in Sema3A signaling www.broad.mit.e...
Broad REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH View Gene Set 0.001214 68 0.02485 21 Genes involved in NCAM signaling for neurite out-growth www.broad.mit.e...
Broad REACTOME_PD1_SIGNALING View Gene Set 0.001405 29 0.02746 22 Genes involved in PD-1 signaling www.broad.mit.e...
Broad REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK View Gene Set 0.001571 48 0.02938 23 Genes involved in NRAGE signals death through JNK www.broad.mit.e...
Broad REACTOME_AXON_GUIDANCE View Gene Set 0.002067 160 0.03077 24 Genes involved in Axon guidance www.broad.mit.e...
Broad REACTOME_PHASE_1_FUNCTIONALIZATION_OF_COMPOUNDS View Gene Set 0.001865 67 0.03077 24 Genes involved in Phase 1 - Functionalization of compounds www.broad.mit.e...
Broad REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION View Gene Set 0.001879 14 0.03077 24 Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion www.broad.mit.e...
Broad REACTOME_SIGNALING_IN_IMMUNE_SYSTEM View Gene Set 0.002009 366 0.03077 24 Genes involved in Signaling in Immune system www.broad.mit.e...
Broad REACTOME_STRIATED_MUSCLE_CONTRACTION View Gene Set 0.001874 31 0.03077 24 Genes involved in Striated Muscle Contraction www.broad.mit.e...
Broad REACTOME_XENOBIOTICS View Gene Set 0.002075 15 0.03077 24 Genes involved in Xenobiotics www.broad.mit.e...

Gene Set Collection: Broad.c3.TFT

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad CAGGTG_V$E12_Q6 View Gene Set 1.313e-08 1818 4.039e-06 1 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CAGGTG which matches annotation for TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) www.broad.mit.e...
Broad TATAAA_V$TATA_01 View Gene Set 1.285e-08 1012 4.039e-06 1 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TATAAA which matches annotation for TAF<br> TATA www.broad.mit.e...
Broad V$AP4_Q6 View Gene Set 5.308e-08 170 6.529e-06 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CWCAGCTGGN which matches annotation for TFAP4: transcription factor AP-4 (activating enhancer binding protein 4) www.broad.mit.e...
Broad V$RP58_01 View Gene Set 5.143e-08 179 6.529e-06 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNAACATCTGGA which matches annotation for ZNF238: zinc finger protein 238 www.broad.mit.e...
Broad V$E2A_Q2 View Gene Set 4.804e-08 179 6.529e-06 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCACCTGYYNCNKN which matches annotation for TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) www.broad.mit.e...
Broad CAGCTG_V$AP4_Q5 View Gene Set 8.824e-08 1129 9.044e-06 6 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CAGCTG which matches annotation for REPIN1: replication initiator 1 www.broad.mit.e...
Broad TGATTTRY_V$GFI1_01 View Gene Set 1.049e-06 234 9.218e-05 7 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TGATTTRY which matches annotation for GFI1: growth factor independent 1 www.broad.mit.e...
Broad CTAWWWATA_V$RSRFC4_Q2 View Gene Set 1.584e-06 283 0.0001218 8 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CTAWWWATA which matches annotation for MEF2A: MADS box transcription enhancer factor 2 polypeptide A (myocyte enhancer factor 2A) www.broad.mit.e...
Broad V$MYOD_Q6_01 View Gene Set 3.437e-06 182 0.0002348 9 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CNGNRNCAGGTGNNGNAN which matches annotation for MYOD1: myogenic differentiation 1 www.broad.mit.e...
Broad V$RSRFC4_01 View Gene Set 4.508e-06 192 0.0002772 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RNKCTATTTWTAGMWN which matches annotation for MEF2A: MADS box transcription enhancer factor 2 polypeptide A (myocyte enhancer factor 2A) www.broad.mit.e...
Broad V$GATA_Q6 View Gene Set 5.399e-06 159 0.0003018 11 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif WGATARN which matches annotation for GATA1: GATA binding protein 1 (globin transcription factor 1) www.broad.mit.e...
Broad GGATTA_V$PITX2_Q2 View Gene Set 8.534e-06 456 0.0004374 12 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGATTA which matches annotation for PITX2: paired-like homeodomain transcription factor 2 www.broad.mit.e...
Broad V$NRSF_01 View Gene Set 2.454e-05 76 0.001161 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTCAGCACCACGGACAGMGCC which matches annotation for REST: RE1-silencing transcription factor www.broad.mit.e...
Broad V$GATA1_04 View Gene Set 3.917e-05 191 0.001639 14 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNCWGATARNNNN which matches annotation for GATA1: GATA binding protein 1 (globin transcription factor 1) www.broad.mit.e...
Broad GATAAGR_V$GATA_C View Gene Set 3.997e-05 232 0.001639 14 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GATAAGR. Motif does not match any known transcription factor www.broad.mit.e...
Broad CAGGTA_V$AREB6_01 View Gene Set 4.444e-05 575 0.001708 16 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CAGGTA which matches annotation for TCF8: transcription factor 8 (represses interleukin 2 expression) www.broad.mit.e...
Broad TAATTA_V$CHX10_01 View Gene Set 5.079e-05 612 0.001838 17 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TAATTA which matches annotation for VSX1: visual system homeobox 1 homolog CHX10-like (zebrafish) www.broad.mit.e...
Broad CAGNWMCNNNGAC_UNKNOWN View Gene Set 5.555e-05 68 0.001898 18 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CAGNWMCNNNGAC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$GATA_C View Gene Set 6.415e-05 204 0.001973 19 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NGATAAGNMNN which matches annotation for GATA1: GATA binding protein 1 (globin transcription factor 1) www.broad.mit.e...
Broad V$GATA6_01 View Gene Set 6.266e-05 191 0.001973 19 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNGATWANN which matches annotation for GATA6: GATA binding protein 6 www.broad.mit.e...
Broad V$OCT_C View Gene Set 7.552e-05 206 0.002111 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CTNATTTGCATAY. Motif does not match any known transcription factor www.broad.mit.e...
Broad TGANTCA_V$AP1_C View Gene Set 7.279e-05 850 0.002111 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TGANTCA which matches annotation for JUN: jun oncogene www.broad.mit.e...
Broad V$OCT1_Q6 View Gene Set 0.0001003 202 0.002681 23 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNATGCAAATNAN which matches annotation for POU2F1: POU domain class 2 transcription factor 1 www.broad.mit.e...
Broad V$E47_01 View Gene Set 0.0001275 201 0.003138 24 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif VSNGCAGGTGKNCNN which matches annotation for TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) www.broad.mit.e...
Broad V$LHX3_01 View Gene Set 0.000126 182 0.003138 24 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif AATTAATTAA which matches annotation for LHX3: LIM homeobox 3 www.broad.mit.e...
Broad V$MMEF2_Q6 View Gene Set 0.0001463 215 0.003461 26 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CKSNYTAAAAAWRMCY. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MEF2_02 View Gene Set 0.0001902 182 0.004333 27 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNNNNNKCTAWAAATAGMNNNN. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$CHX10_01 View Gene Set 0.0002026 182 0.004451 28 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNTAATTAGCNNN which matches annotation for VSX1: visual system homeobox 1 homolog CHX10-like (zebrafish) www.broad.mit.e...
Broad V$MEF2_Q6_01 View Gene Set 0.0002244 191 0.004759 29 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif RGCTATWTTTAR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$OCT1_B View Gene Set 0.0002469 213 0.005062 30 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TATGCAAATN which matches annotation for POU2F1: POU domain class 2 transcription factor 1 www.broad.mit.e...
Broad V$S8_01 View Gene Set 0.0003181 195 0.00631 31 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif WNNANYYAATTANCNN which matches annotation for PRRX2: paired related homeobox 2 www.broad.mit.e...
Broad V$OCT1_Q5_01 View Gene Set 0.0004182 209 0.008037 32 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TNATTTGCATW which matches annotation for POU2F1: POU domain class 2 transcription factor 1 www.broad.mit.e...
Broad TGTTTGY_V$HNF3_Q6 View Gene Set 0.0004638 560 0.008643 33 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TGTTTGY which matches annotation for FOXA1: forkhead box A1 www.broad.mit.e...
Broad V$ARP1_01 View Gene Set 0.000481 122 0.008701 34 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TGARCCYTTGAMCCCW which matches annotation for PITX2: paired-like homeodomain transcription factor 2 www.broad.mit.e...
Broad V$MEF2_03 View Gene Set 0.0005238 184 0.008796 35 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNNNNWKCTAWAAATAGMNNNN. Motif does not match any known transcription factor www.broad.mit.e...
Broad YATTNATC_UNKNOWN View Gene Set 0.0005292 275 0.008796 35 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif YATTNATC. Motif does not match any known transcription factor www.broad.mit.e...
Broad GGGTGGRR_V$PAX4_03 View Gene Set 0.0005269 994 0.008796 35 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGGTGGRR which matches annotation for PAX4: paired box gene 4 www.broad.mit.e...
Broad V$OCT1_05 View Gene Set 0.0005894 201 0.009483 38 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif MKVATTTGCATATT which matches annotation for POU2F1: POU domain class 2 transcription factor 1 www.broad.mit.e...
Broad GCANCTGNY_V$MYOD_Q6 View Gene Set 0.0006014 673 0.009483 38 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCANCTGNY which matches annotation for MYOD1: myogenic differentiation 1 www.broad.mit.e...
Broad V$TATA_01 View Gene Set 0.0006193 218 0.009522 40 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif STATAAAWRNNNNNN which matches annotation for TAF<br> TATA www.broad.mit.e...
Broad V$HNF1_C View Gene Set 0.0006511 174 0.009534 41 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif DGTTAATKAWTNACCAM which matches annotation for TCF1: transcription factor 1 hepatic; LF-B1 hepatic nuclear factor (HNF1) albumin proximal factor www.broad.mit.e...
Broad YATGNWAAT_V$OCT_C View Gene Set 0.0006503 289 0.009534 41 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif YATGNWAAT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$HMEF2_Q6 View Gene Set 0.0007413 108 0.0106 43 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif SKYTAAAAATAACYCH. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$OCT_Q6 View Gene Set 0.0008624 206 0.01205 44 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TNATTTGCATN. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$TBP_01 View Gene Set 0.001228 189 0.01678 45 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TATAAATW which matches annotation for TBP: TATA box binding protein www.broad.mit.e...
Broad GGGAGGRR_V$MAZ_Q6 View Gene Set 0.001263 1701 0.01689 46 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGGAGGRR which matches annotation for MAZ: MYC-associated zinc finger protein (purine-binding transcription factor) www.broad.mit.e...
Broad CTGCAGY_UNKNOWN View Gene Set 0.001314 570 0.01719 47 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CTGCAGY. Motif does not match any known transcription factor www.broad.mit.e...
Broad GTGGGTGK_UNKNOWN View Gene Set 0.001403 224 0.01798 48 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GTGGGTGK. Motif does not match any known transcription factor www.broad.mit.e...
Broad TGGNNNNNNKCCAR_UNKNOWN View Gene Set 0.001546 314 0.0194 49 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TGGNNNNNNKCCAR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$TAL1BETAITF2_01 View Gene Set 0.001936 191 0.02334 50 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNAACAGATGKTNNN which matches annotation for TAL1: T-cell acute lymphocytic leukemia 1<br> TCF4: transcription factor 4 www.broad.mit.e...
Broad V$AMEF2_Q6 View Gene Set 0.001911 194 0.02334 50 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CKGDYTAAAAATAACYMM. Motif does not match any known transcription factor www.broad.mit.e...
Broad TAAYNRNNTCC_UNKNOWN View Gene Set 0.002076 129 0.02436 52 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TAAYNRNNTCC. Motif does not match any known transcription factor www.broad.mit.e...
Broad TGCCAAR_V$NF1_Q6 View Gene Set 0.002099 532 0.02436 52 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TGCCAAR which matches annotation for NF1: neurofibromin 1 (neurofibromatosis von Recklinghausen disease Watson disease) www.broad.mit.e...
Broad V$GATA3_01 View Gene Set 0.00219 185 0.02493 54 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNGATARNG which matches annotation for GATA3: GATA binding protein 3 www.broad.mit.e...
Broad V$AFP1_Q6 View Gene Set 0.002229 198 0.02493 54 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif ATTAAYTRCAC which matches annotation for ZHX2: zinc fingers and homeoboxes 2 www.broad.mit.e...
Broad V$MEF2_01 View Gene Set 0.002398 117 0.02633 56 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CTCTAAAAATAACYCY. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$IK2_01 View Gene Set 0.002709 208 0.02918 57 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNNTGGGAWNNC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$PBX1_02 View Gene Set 0.00277 107 0.02918 57 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNCATCAATCAANNW which matches annotation for PBX1: pre-B-cell leukemia transcription factor 1 www.broad.mit.e...
Broad V$NKX25_02 View Gene Set 0.002846 199 0.02918 57 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CWTAATTG which matches annotation for NKX2-5: NK2 transcription factor related locus 5 (Drosophila) www.broad.mit.e...
Broad RGTTAMWNATT_V$HNF1_01 View Gene Set 0.002802 56 0.02918 57 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RGTTAMWNATT which matches annotation for TCF1: transcription factor 1 hepatic; LF-B1 hepatic nuclear factor (HNF1) albumin proximal factor www.broad.mit.e...
Broad V$RSRFC4_Q2 View Gene Set 0.002994 168 0.03019 61 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif ANKCTAWAAATAGMHNN which matches annotation for MEF2A: MADS box transcription enhancer factor 2 polypeptide A (myocyte enhancer factor 2A) www.broad.mit.e...
Broad V$LBP1_Q6 View Gene Set 0.00323 164 0.03204 62 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CAGCTGS which matches annotation for UBP1: upstream binding protein 1 (LBP-1a) www.broad.mit.e...
Broad V$E47_02 View Gene Set 0.003374 188 0.03231 63 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNMRCAGGTGTTMNN which matches annotation for TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) www.broad.mit.e...
Broad V$MYOD_Q6 View Gene Set 0.00352 187 0.03231 63 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNCACCTGNY which matches annotation for MYOD1: myogenic differentiation 1 www.broad.mit.e...
Broad V$MSX1_01 View Gene Set 0.003373 145 0.03231 63 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CNGTAWNTG which matches annotation for MSX1: msh homeobox homolog 1 (Drosophila) www.broad.mit.e...
Broad V$E12_Q6 View Gene Set 0.003435 191 0.03231 63 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RRCAGGTGNCV which matches annotation for TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) www.broad.mit.e...
Broad RAAGNYNNCTTY_UNKNOWN View Gene Set 0.003475 110 0.03231 63 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif RAAGNYNNCTTY. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$LMO2COM_02 View Gene Set 0.003591 194 0.03248 68 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NMGATANSG which matches annotation for LMO2: LIM domain only 2 (rhombotin-like 1) www.broad.mit.e...
Broad V$GATA1_02 View Gene Set 0.00386 183 0.03297 69 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNGATANKGNN which matches annotation for GATA1: GATA binding protein 1 (globin transcription factor 1) www.broad.mit.e...
Broad V$AML_Q6 View Gene Set 0.003746 196 0.03297 69 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNGKNTGTGGTTWNC which matches annotation for RUNX1: runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) www.broad.mit.e...
Broad V$SREBP_Q3 View Gene Set 0.003857 185 0.03297 69 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif VNNVTCACCCYA. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$AP4_Q6_01 View Gene Set 0.00385 191 0.03297 69 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RNCAGCTGC which matches annotation for TFAP4: transcription factor AP-4 (activating enhancer binding protein 4) www.broad.mit.e...
Broad V$FREAC4_01 View Gene Set 0.004029 111 0.03394 73 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CTWAWGTAAACANWGN which matches annotation for FOXD1: forkhead box D1 www.broad.mit.e...
Broad V$HEB_Q6 View Gene Set 0.004453 200 0.037 74 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RCCWGCTG which matches annotation for TCF12: transcription factor 12 (HTF4 helix-loop-helix transcription factors 4) www.broad.mit.e...
Broad V$NKX62_Q2 View Gene Set 0.004517 187 0.03704 75 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NWADTAAWTANN which matches annotation for NKX6-2: NK6 transcription factor related locus 2 (Drosophila) www.broad.mit.e...
Broad V$TAL1BETAE47_01 View Gene Set 0.004594 184 0.03718 76 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNAACAGATGKTNNN which matches annotation for TAL1: T-cell acute lymphocytic leukemia 1<br> TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) www.broad.mit.e...
Broad V$NF1_Q6 View Gene Set 0.005127 206 0.04043 77 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNTTGGCNNNNNNCCNNN which matches annotation for NF1: neurofibromin 1 (neurofibromatosis von Recklinghausen disease Watson disease) www.broad.mit.e...
Broad TTCYNRGAA_V$STAT5B_01 View Gene Set 0.005102 247 0.04043 77 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTCYNRGAA which matches annotation for STAT5B: signal transducer and activator of transcription 5B www.broad.mit.e...
Broad V$IRF_Q6 View Gene Set 0.005317 174 0.04139 79 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif BNCRSTTTCANTTYY which matches annotation for IRF1: interferon regulatory factor 1 www.broad.mit.e...
Broad WGGAATGY_V$TEF1_Q6 View Gene Set 0.005619 281 0.0432 80 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif WGGAATGY which matches annotation for TEAD1: TEA domain family member 1 (SV40 transcriptional enhancer factor) www.broad.mit.e...
Broad V$HNF3B_01 View Gene Set 0.005963 173 0.04488 81 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif KGNANTRTTTRYTTW which matches annotation for FOXA2: forkhead box A2 www.broad.mit.e...
Broad YCATTAA_UNKNOWN View Gene Set 0.005984 426 0.04488 81 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif YCATTAA. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$AREB6_02 View Gene Set 0.006111 189 0.04528 83 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif WNWCACCTGWNN which matches annotation for TCF8: transcription factor 8 (represses interleukin 2 expression) www.broad.mit.e...
Broad V$HNF1_01 View Gene Set 0.006524 183 0.04765 84 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGTTAATNWTTAMCN which matches annotation for TCF1: transcription factor 1 hepatic; LF-B1 hepatic nuclear factor (HNF1) albumin proximal factor www.broad.mit.e...
Broad TGACATY_UNKNOWN View Gene Set 0.006586 503 0.04765 84 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TGACATY. Motif does not match any known transcription factor www.broad.mit.e...

Gene Set Collection: Broad.c4.CGN

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad MORF_MAGEA9 View Gene Set 4.062e-09 405 1.735e-06 1 Neighborhood of MAGEA9 www.broad.mit.e...
Broad MORF_ARL3 View Gene Set 9.178e-09 291 1.959e-06 2 Neighborhood of ARL3 www.broad.mit.e...
Broad MORF_NOS2A View Gene Set 1.99e-08 276 2.833e-06 3 Neighborhood of NOS2A www.broad.mit.e...
Broad MORF_FOSL1 View Gene Set 3.103e-08 386 3.313e-06 4 Neighborhood of FOSL1 www.broad.mit.e...
Broad MORF_ERCC4 View Gene Set 5.928e-08 309 5.063e-06 5 Neighborhood of ERCC4 www.broad.mit.e...
Broad MORF_PAX7 View Gene Set 2.486e-07 251 1.769e-05 6 Neighborhood of PAX7 www.broad.mit.e...
Broad MORF_BCL2 View Gene Set 4.242e-07 202 2.5e-05 7 Neighborhood of BCL2 www.broad.mit.e...
Broad MORF_RAD51L3 View Gene Set 5.269e-07 371 2.5e-05 7 Neighborhood of RAD51L3 www.broad.mit.e...
Broad MORF_ETV3 View Gene Set 5.079e-07 63 2.5e-05 7 Neighborhood of ETV3 www.broad.mit.e...
Broad MORF_NF1 View Gene Set 9.074e-07 158 3.875e-05 10 Neighborhood of NF1 www.broad.mit.e...
Broad MORF_MAP2K7 View Gene Set 4.399e-06 179 0.0001708 11 Neighborhood of MAP2K7 www.broad.mit.e...
Broad GNF2_MAPT View Gene Set 5.757e-06 38 0.0002049 12 Neighborhood of MAPT www.broad.mit.e...
Broad MORF_SUPT3H View Gene Set 7.19e-06 318 0.0002188 13 Neighborhood of SUPT3H www.broad.mit.e...
Broad MORF_TNFRSF25 View Gene Set 7.686e-06 242 0.0002188 13 Neighborhood of TNFRSF25 www.broad.mit.e...
Broad GNF2_CDH3 View Gene Set 7.459e-06 24 0.0002188 13 Neighborhood of CDH3 www.broad.mit.e...
Broad MORF_CD8A View Gene Set 9.732e-06 121 0.0002597 16 Neighborhood of CD8A www.broad.mit.e...
Broad GNF2_TIMP2 View Gene Set 1.175e-05 45 0.0002952 17 Neighborhood of TIMP2 www.broad.mit.e...
Broad MORF_FLT1 View Gene Set 1.304e-05 117 0.0003093 18 Neighborhood of FLT1 www.broad.mit.e...
Broad MORF_FSHR View Gene Set 1.717e-05 268 0.0003666 19 Neighborhood of FSHR www.broad.mit.e...
Broad GNF2_TM4SF2 View Gene Set 1.689e-05 23 0.0003666 19 Neighborhood of TM4SF2 www.broad.mit.e...
Broad GNF2_DNM1 View Gene Set 2.215e-05 69 0.0004504 21 Neighborhood of DNM1 www.broad.mit.e...
Broad GNF2_KISS1 View Gene Set 2.612e-05 48 0.0005069 22 Neighborhood of KISS1 www.broad.mit.e...
Broad MORF_CAMK4 View Gene Set 3.053e-05 281 0.0005432 23 Neighborhood of CAMK4 www.broad.mit.e...
Broad GNF2_MMP11 View Gene Set 2.926e-05 41 0.0005432 23 Neighborhood of MMP11 www.broad.mit.e...
Broad MORF_ATF2 View Gene Set 4.502e-05 318 0.000769 25 Neighborhood of ATF2 www.broad.mit.e...
Broad MORF_TFDP2 View Gene Set 5.92e-05 215 0.0009722 26 Neighborhood of TFDP2 www.broad.mit.e...
Broad GNF2_IGFBP1 View Gene Set 6.221e-05 35 0.0009839 27 Neighborhood of IGFBP1 www.broad.mit.e...
Broad MORF_MAGEA8 View Gene Set 0.0001053 250 0.001478 28 Neighborhood of MAGEA8 www.broad.mit.e...
Broad GNF2_CCNA1 View Gene Set 0.0001073 59 0.001478 28 Neighborhood of CCNA1 www.broad.mit.e...
Broad GNF2_SERPINB5 View Gene Set 0.0001069 25 0.001478 28 Neighborhood of SERPINB5 www.broad.mit.e...
Broad GNF2_VAV1 View Gene Set 9.991e-05 34 0.001478 28 Neighborhood of VAV1 www.broad.mit.e...
Broad MORF_STK17A View Gene Set 0.0001172 155 0.001564 32 Neighborhood of STK17A www.broad.mit.e...
Broad MORF_MDM2 View Gene Set 0.0001288 269 0.001667 33 Neighborhood of MDM2 www.broad.mit.e...
Broad GNF2_RAB3A View Gene Set 0.0001445 34 0.001815 34 Neighborhood of RAB3A www.broad.mit.e...
Broad MORF_MYL3 View Gene Set 0.0001762 69 0.00215 35 Neighborhood of MYL3 www.broad.mit.e...
Broad MORF_CDH4 View Gene Set 0.0002001 134 0.002373 36 Neighborhood of CDH4 www.broad.mit.e...
Broad MORF_JAG1 View Gene Set 0.0002205 87 0.00239 37 Neighborhood of JAG1 www.broad.mit.e...
Broad GNF2_GSTM1 View Gene Set 0.0002219 108 0.00239 37 Neighborhood of GSTM1 www.broad.mit.e...
Broad GNF2_HPX View Gene Set 0.0002239 134 0.00239 37 Neighborhood of HPX www.broad.mit.e...
Broad GNF2_LCAT View Gene Set 0.0002119 123 0.00239 37 Neighborhood of LCAT www.broad.mit.e...
Broad MORF_IFNA1 View Gene Set 0.0002363 198 0.002461 41 Neighborhood of IFNA1 www.broad.mit.e...
Broad GNF2_IL2RB View Gene Set 0.0003054 44 0.003105 42 Neighborhood of IL2RB www.broad.mit.e...
Broad MORF_IL13 View Gene Set 0.0003171 216 0.003123 43 Neighborhood of IL13 www.broad.mit.e...
Broad GNF2_HPN View Gene Set 0.0003218 132 0.003123 43 Neighborhood of HPN www.broad.mit.e...
Broad MORF_IL4 View Gene Set 0.0003537 186 0.003357 45 Neighborhood of IL4 www.broad.mit.e...
Broad MORF_BCL2L11 View Gene Set 0.0003712 178 0.003445 46 Neighborhood of BCL2L11 www.broad.mit.e...
Broad MORF_CTSB View Gene Set 0.0003792 182 0.003445 46 Neighborhood of CTSB www.broad.mit.e...
Broad MORF_KDR View Gene Set 0.0005014 90 0.004461 48 Neighborhood of KDR www.broad.mit.e...
Broad MORF_MLLT10 View Gene Set 0.0005133 290 0.004473 49 Neighborhood of MLLT10 www.broad.mit.e...
Broad GCM_PTPRU View Gene Set 0.0005645 55 0.004821 50 Neighborhood of PTPRU www.broad.mit.e...
Broad GCM_HMGA2 View Gene Set 0.0005912 123 0.00495 51 Neighborhood of HMGA2 www.broad.mit.e...
Broad GNF2_TST View Gene Set 0.0006378 103 0.005237 52 Neighborhood of TST www.broad.mit.e...
Broad MORF_PTPRR View Gene Set 0.0007347 98 0.00592 53 Neighborhood of PTPRR www.broad.mit.e...
Broad GNF2_PTPRC View Gene Set 0.000811 60 0.006413 54 Neighborhood of PTPRC www.broad.mit.e...
Broad GNF2_CYP2B6 View Gene Set 0.0008982 49 0.006973 55 Neighborhood of CYP2B6 www.broad.mit.e...
Broad GNF2_ICAM3 View Gene Set 0.0009793 36 0.007468 56 Neighborhood of ICAM3 www.broad.mit.e...
Broad MORF_THRA View Gene Set 0.001189 50 0.00891 57 Neighborhood of THRA www.broad.mit.e...
Broad GNF2_CEBPA View Gene Set 0.00134 64 0.009862 58 Neighborhood of CEBPA www.broad.mit.e...
Broad GNF2_MLF1 View Gene Set 0.001417 76 0.01026 59 Neighborhood of MLF1 www.broad.mit.e...
Broad GNF2_CD97 View Gene Set 0.001584 37 0.01127 60 Neighborhood of CD97 www.broad.mit.e...
Broad GNF2_CDKN1C View Gene Set 0.00161 27 0.01127 61 Neighborhood of CDKN1C www.broad.mit.e...
Broad MORF_PRKCA View Gene Set 0.001646 174 0.01134 62 Neighborhood of PRKCA www.broad.mit.e...
Broad MORF_RAGE View Gene Set 0.001732 132 0.01174 63 Neighborhood of RAGE www.broad.mit.e...
Broad MORF_MT4 View Gene Set 0.001804 218 0.01196 64 Neighborhood of MT4 www.broad.mit.e...
Broad MORF_MAP3K14 View Gene Set 0.00182 110 0.01196 64 Neighborhood of MAP3K14 www.broad.mit.e...
Broad MORF_PTPRB View Gene Set 0.001922 241 0.0124 66 Neighborhood of PTPRB www.broad.mit.e...
Broad CAR_HPX View Gene Set 0.001952 73 0.0124 66 Neighborhood of HPX www.broad.mit.e...
Broad GNF2_RTN1 View Gene Set 0.001974 45 0.0124 66 Neighborhood of RTN1 www.broad.mit.e...
Broad CAR_IGFBP1 View Gene Set 0.002207 57 0.01366 69 Neighborhood of IGFBP1 www.broad.mit.e...
Broad MORF_IL16 View Gene Set 0.002261 227 0.01379 70 Neighborhood of IL16 www.broad.mit.e...
Broad GNF2_CD7 View Gene Set 0.00236 38 0.01419 71 Neighborhood of CD7 www.broad.mit.e...
Broad MORF_LTK View Gene Set 0.002504 133 0.01485 72 Neighborhood of LTK www.broad.mit.e...
Broad GNF2_SPINK1 View Gene Set 0.002716 24 0.01589 73 Neighborhood of SPINK1 www.broad.mit.e...
Broad MORF_JAK3 View Gene Set 0.002809 86 0.01611 74 Neighborhood of JAK3 www.broad.mit.e...
Broad GNF2_TTN View Gene Set 0.002829 26 0.01611 74 Neighborhood of TTN www.broad.mit.e...
Broad MORF_LMO1 View Gene Set 0.003139 46 0.01763 76 Neighborhood of LMO1 www.broad.mit.e...
Broad GNF2_ITGAL View Gene Set 0.003363 49 0.01865 77 Neighborhood of ITGAL www.broad.mit.e...
Broad MORF_PPP2R5B View Gene Set 0.003474 162 0.01902 78 Neighborhood of PPP2R5B www.broad.mit.e...
Broad GCM_CDH5 View Gene Set 0.003898 35 0.02107 79 Neighborhood of CDH5 www.broad.mit.e...
Broad GNF2_CARD15 View Gene Set 0.004264 62 0.02248 80 Neighborhood of CARD15 www.broad.mit.e...
Broad GNF2_MYL3 View Gene Set 0.004258 31 0.02248 80 Neighborhood of MYL3 www.broad.mit.e...
Broad GNF2_SERPINI2 View Gene Set 0.0051 21 0.02656 82 Neighborhood of SERPINI2 www.broad.mit.e...
Broad GNF2_PTPN4 View Gene Set 0.005245 47 0.02698 83 Neighborhood of PTPN4 www.broad.mit.e...
Broad GNF2_MYL2 View Gene Set 0.006762 32 0.03437 84 Neighborhood of MYL2 www.broad.mit.e...
Broad MORF_WNT1 View Gene Set 0.00694 99 0.03486 85 Neighborhood of WNT1 www.broad.mit.e...
Broad GCM_LTK View Gene Set 0.007073 43 0.03512 86 Neighborhood of LTK www.broad.mit.e...
Broad GNF2_HLA-C View Gene Set 0.007235 44 0.03551 87 Neighborhood of HLA-C www.broad.mit.e...
Broad GNF2_MATK View Gene Set 0.008047 23 0.03905 88 Neighborhood of MATK www.broad.mit.e...
Broad GCM_TEC View Gene Set 0.008789 33 0.04217 89 Neighborhood of TEC www.broad.mit.e...
Broad GNF2_S100A4 View Gene Set 0.008905 43 0.04225 90 Neighborhood of S100A4 www.broad.mit.e...
Broad GNF2_EGFR View Gene Set 0.00902 32 0.04233 91 Neighborhood of EGFR www.broad.mit.e...
Broad CAR_MLANA View Gene Set 0.009943 42 0.04615 92 Neighborhood of MLANA www.broad.mit.e...
Broad GNF2_IGF1 View Gene Set 0.01005 26 0.04616 93 Neighborhood of IGF1 www.broad.mit.e...
Broad GNF2_CD48 View Gene Set 0.01049 31 0.04764 94 Neighborhood of CD48 www.broad.mit.e...

Gene Set Collection: Broad.c4.CM

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad module_64 View Gene Set 1.361e-23 506 6.181e-21 1 Genes in module_64 www.broad.mit.e...
Broad module_84 View Gene Set 5.853e-23 526 1.329e-20 2 Genes in module_84 www.broad.mit.e...
Broad module_55 View Gene Set 1.452e-22 807 2.197e-20 3 Genes in module_55 www.broad.mit.e...
Broad module_88 View Gene Set 3.344e-22 812 3.796e-20 4 Genes in module_88 www.broad.mit.e...
Broad module_117 View Gene Set 7.313e-21 699 6.1e-19 5 Genes in module_117 www.broad.mit.e...
Broad module_220 View Gene Set 8.061e-21 328 6.1e-19 5 Genes in module_220 www.broad.mit.e...
Broad module_66 View Gene Set 1.661e-20 530 1.077e-18 7 Genes in module_66 www.broad.mit.e...
Broad module_100 View Gene Set 2.198e-20 523 1.248e-18 8 Genes in module_100 www.broad.mit.e...
Broad module_137 View Gene Set 1.719e-19 525 8.674e-18 9 Genes in module_137 www.broad.mit.e...
Broad module_75 View Gene Set 1.09e-15 391 4.949e-14 10 Genes in module_75 www.broad.mit.e...
Broad module_11 View Gene Set 2.472e-15 520 1.02e-13 11 Genes in module_11 www.broad.mit.e...
Broad module_45 View Gene Set 1.207e-14 563 4.565e-13 12 Genes in module_45 www.broad.mit.e...
Broad module_46 View Gene Set 1.712e-14 386 5.978e-13 13 Genes in module_46 www.broad.mit.e...
Broad module_2 View Gene Set 5.636e-13 373 1.828e-11 14 Genes in module_2 www.broad.mit.e...
Broad module_27 View Gene Set 1.098e-12 345 3.116e-11 15 Genes in module_27 www.broad.mit.e...
Broad module_41 View Gene Set 1.055e-12 542 3.116e-11 15 Genes in module_41 www.broad.mit.e...
Broad module_47 View Gene Set 1.331e-12 216 3.555e-11 17 Genes in module_47 www.broad.mit.e...
Broad module_12 View Gene Set 2.93e-12 346 7.391e-11 18 Genes in module_12 www.broad.mit.e...
Broad module_112 View Gene Set 1.572e-11 255 3.756e-10 19 Genes in module_112 www.broad.mit.e...
Broad module_1 View Gene Set 1.923e-11 355 4.366e-10 20 Genes in module_1 www.broad.mit.e...
Broad module_5 View Gene Set 3.68e-11 420 7.957e-10 21 Genes in module_5 www.broad.mit.e...
Broad module_176 View Gene Set 2.545e-10 225 5.252e-09 22 Genes in module_176 www.broad.mit.e...
Broad module_6 View Gene Set 4.251e-10 403 8.392e-09 23 Genes in module_6 www.broad.mit.e...
Broad module_38 View Gene Set 5.052e-10 453 9.556e-09 24 Genes in module_38 www.broad.mit.e...
Broad module_104 View Gene Set 2.255e-09 337 4.096e-08 25 Genes in module_104 www.broad.mit.e...
Broad module_60 View Gene Set 4.325e-09 403 7.552e-08 26 Genes in module_60 www.broad.mit.e...
Broad module_63 View Gene Set 8.658e-09 210 1.456e-07 27 Genes in module_63 www.broad.mit.e...
Broad module_122 View Gene Set 1.164e-08 138 1.887e-07 28 Genes in module_122 www.broad.mit.e...
Broad module_23 View Gene Set 1.474e-08 552 2.291e-07 29 Genes in module_23 www.broad.mit.e...
Broad module_33 View Gene Set 1.514e-08 369 2.291e-07 29 Genes in module_33 www.broad.mit.e...
Broad module_99 View Gene Set 2.5e-08 346 3.661e-07 31 Genes in module_99 www.broad.mit.e...
Broad module_44 View Gene Set 8.375e-08 319 1.188e-06 32 Genes in module_44 www.broad.mit.e...
Broad module_181 View Gene Set 1.017e-07 292 1.399e-06 33 Genes in module_181 www.broad.mit.e...
Broad module_24 View Gene Set 1.284e-07 443 1.714e-06 34 Genes in module_24 www.broad.mit.e...
Broad module_92 View Gene Set 1.947e-07 146 2.525e-06 35 Genes in module_92 www.broad.mit.e...
Broad module_289 View Gene Set 4.721e-07 118 5.954e-06 36 Genes in module_289 www.broad.mit.e...
Broad module_113 View Gene Set 4.53e-06 105 5.559e-05 37 Genes in module_113 www.broad.mit.e...
Broad module_111 View Gene Set 4.71e-06 151 5.628e-05 38 Genes in module_111 www.broad.mit.e...
Broad module_94 View Gene Set 5.133e-06 362 5.975e-05 39 Genes in module_94 www.broad.mit.e...
Broad module_324 View Gene Set 7.964e-06 131 9.04e-05 40 Genes in module_324 www.broad.mit.e...
Broad module_436 View Gene Set 1.115e-05 129 0.0001235 41 Genes in module_436 www.broad.mit.e...
Broad module_242 View Gene Set 1.146e-05 204 0.0001239 42 Genes in module_242 www.broad.mit.e...
Broad module_316 View Gene Set 2.007e-05 70 0.0002119 43 Genes in module_316 www.broad.mit.e...
Broad module_157 View Gene Set 2.206e-05 105 0.0002226 44 Genes in module_157 www.broad.mit.e...
Broad module_489 View Gene Set 2.195e-05 30 0.0002226 44 Genes in module_489 www.broad.mit.e...
Broad module_433 View Gene Set 3.213e-05 60 0.0003171 46 Genes in module_433 www.broad.mit.e...
Broad module_292 View Gene Set 3.405e-05 129 0.0003289 47 Genes in module_292 www.broad.mit.e...
Broad module_345 View Gene Set 3.547e-05 118 0.0003355 48 Genes in module_345 www.broad.mit.e...
Broad module_154 View Gene Set 3.836e-05 73 0.0003554 49 Genes in module_154 www.broad.mit.e...
Broad module_379 View Gene Set 3.96e-05 194 0.0003596 50 Genes in module_379 www.broad.mit.e...
Broad module_223 View Gene Set 6.101e-05 140 0.0005431 51 Genes in module_223 www.broad.mit.e...
Broad module_297 View Gene Set 6.302e-05 78 0.0005502 52 Genes in module_297 www.broad.mit.e...
Broad module_199 View Gene Set 6.507e-05 57 0.0005574 53 Genes in module_199 www.broad.mit.e...
Broad module_171 View Gene Set 7.563e-05 131 0.0006358 54 Genes in module_171 www.broad.mit.e...
Broad module_375 View Gene Set 9.505e-05 84 0.0007846 55 Genes in module_375 www.broad.mit.e...
Broad module_357 View Gene Set 0.0001094 78 0.0008865 56 Genes in module_357 www.broad.mit.e...
Broad module_213 View Gene Set 0.0001153 77 0.0009183 57 Genes in module_213 www.broad.mit.e...
Broad module_274 View Gene Set 0.0001356 82 0.001062 58 Genes in module_274 www.broad.mit.e...
Broad module_287 View Gene Set 0.0001428 49 0.001099 59 Genes in module_287 www.broad.mit.e...
Broad module_259 View Gene Set 0.0001725 46 0.001302 60 Genes in module_259 www.broad.mit.e...
Broad module_263 View Gene Set 0.000175 43 0.001302 60 Genes in module_263 www.broad.mit.e...
Broad module_119 View Gene Set 0.0002195 135 0.001607 62 Genes in module_119 www.broad.mit.e...
Broad module_146 View Gene Set 0.0002921 92 0.002105 63 Genes in module_146 www.broad.mit.e...
Broad module_329 View Gene Set 0.0003081 51 0.002186 64 Genes in module_329 www.broad.mit.e...
Broad module_108 View Gene Set 0.0003347 52 0.002338 65 Genes in module_108 www.broad.mit.e...
Broad module_208 View Gene Set 0.0003399 118 0.002338 65 Genes in module_208 www.broad.mit.e...
Broad module_130 View Gene Set 0.0004393 23 0.002933 67 Genes in module_130 www.broad.mit.e...
Broad module_367 View Gene Set 0.000434 27 0.002933 67 Genes in module_367 www.broad.mit.e...
Broad module_387 View Gene Set 0.0005365 49 0.00353 69 Genes in module_387 www.broad.mit.e...
Broad module_13 View Gene Set 0.0005711 498 0.003652 70 Genes in module_13 www.broad.mit.e...
Broad module_96 View Gene Set 0.0005705 36 0.003652 70 Genes in module_96 www.broad.mit.e...
Broad module_400 View Gene Set 0.0007743 19 0.004882 72 Genes in module_400 www.broad.mit.e...
Broad module_248 View Gene Set 0.0008654 126 0.005382 73 Genes in module_248 www.broad.mit.e...
Broad module_513 View Gene Set 0.000936 8 0.005743 74 Genes in module_513 www.broad.mit.e...
Broad module_76 View Gene Set 0.0009531 79 0.005769 75 Genes in module_76 www.broad.mit.e...
Broad module_143 View Gene Set 0.0009718 14 0.005805 76 Genes in module_143 www.broad.mit.e...
Broad module_190 View Gene Set 0.001031 12 0.006081 77 Genes in module_190 www.broad.mit.e...
Broad module_131 View Gene Set 0.001064 33 0.006194 78 Genes in module_131 www.broad.mit.e...
Broad module_144 View Gene Set 0.001104 8 0.006347 79 Genes in module_144 www.broad.mit.e...
Broad module_109 View Gene Set 0.001172 34 0.006652 80 Genes in module_109 www.broad.mit.e...
Broad module_293 View Gene Set 0.001201 12 0.006731 81 Genes in module_293 www.broad.mit.e...
Broad module_174 View Gene Set 0.001233 92 0.006825 82 Genes in module_174 www.broad.mit.e...
Broad module_129 View Gene Set 0.001348 215 0.007374 83 Genes in module_129 www.broad.mit.e...
Broad module_85 View Gene Set 0.001513 51 0.008179 84 Genes in module_85 www.broad.mit.e...
Broad module_301 View Gene Set 0.001612 144 0.008517 85 Genes in module_301 www.broad.mit.e...
Broad module_410 View Gene Set 0.001613 35 0.008517 85 Genes in module_410 www.broad.mit.e...
Broad module_58 View Gene Set 0.001814 21 0.009436 87 Genes in module_58 www.broad.mit.e...
Broad module_121 View Gene Set 0.001829 98 0.009436 87 Genes in module_121 www.broad.mit.e...
Broad module_474 View Gene Set 0.001865 16 0.009514 89 Genes in module_474 www.broad.mit.e...
Broad module_512 View Gene Set 0.002385 37 0.01203 90 Genes in module_512 www.broad.mit.e...
Broad module_361 View Gene Set 0.002425 136 0.0121 91 Genes in module_361 www.broad.mit.e...
Broad module_201 View Gene Set 0.00284 50 0.01389 92 Genes in module_201 www.broad.mit.e...
Broad module_234 View Gene Set 0.002846 53 0.01389 92 Genes in module_234 www.broad.mit.e...
Broad module_128 View Gene Set 0.003003 98 0.0145 94 Genes in module_128 www.broad.mit.e...
Broad module_382 View Gene Set 0.00314 28 0.01501 95 Genes in module_382 www.broad.mit.e...
Broad module_238 View Gene Set 0.003274 150 0.01548 96 Genes in module_238 www.broad.mit.e...
Broad module_79 View Gene Set 0.003709 100 0.01718 97 Genes in module_79 www.broad.mit.e...
Broad module_418 View Gene Set 0.003709 56 0.01718 97 Genes in module_418 www.broad.mit.e...
Broad module_170 View Gene Set 0.003817 100 0.0175 99 Genes in module_170 www.broad.mit.e...
Broad module_165 View Gene Set 0.005103 78 0.02317 100 Genes in module_165 www.broad.mit.e...
Broad module_205 View Gene Set 0.005259 259 0.02364 101 Genes in module_205 www.broad.mit.e...
Broad module_164 View Gene Set 0.005322 61 0.02369 102 Genes in module_164 www.broad.mit.e...
Broad module_107 View Gene Set 0.005825 77 0.02568 103 Genes in module_107 www.broad.mit.e...
Broad module_7 View Gene Set 0.006399 227 0.02786 104 Genes in module_7 www.broad.mit.e...
Broad module_368 View Gene Set 0.006443 18 0.02786 104 Genes in module_368 www.broad.mit.e...
Broad module_200 View Gene Set 0.006787 27 0.02907 106 Genes in module_200 www.broad.mit.e...
Broad module_497 View Gene Set 0.008189 29 0.03474 107 Genes in module_497 www.broad.mit.e...
Broad module_51 View Gene Set 0.008329 36 0.03501 108 Genes in module_51 www.broad.mit.e...
Broad module_20 View Gene Set 0.008491 81 0.03537 109 Genes in module_20 www.broad.mit.e...
Broad module_188 View Gene Set 0.00877 130 0.03587 110 Genes in module_188 www.broad.mit.e...
Broad module_288 View Gene Set 0.008724 34 0.03587 110 Genes in module_288 www.broad.mit.e...
Broad module_311 View Gene Set 0.009352 18 0.03791 112 Genes in module_311 www.broad.mit.e...
Broad module_426 View Gene Set 0.01003 82 0.04009 113 Genes in module_426 www.broad.mit.e...
Broad module_478 View Gene Set 0.01007 19 0.04009 113 Genes in module_478 www.broad.mit.e...
Broad module_134 View Gene Set 0.01101 28 0.04345 115 Genes in module_134 www.broad.mit.e...
Broad module_291 View Gene Set 0.01111 63 0.04347 116 Genes in module_291 www.broad.mit.e...
Broad module_80 View Gene Set 0.01136 32 0.0441 117 Genes in module_80 www.broad.mit.e...
Broad module_153 View Gene Set 0.01149 34 0.04422 118 Genes in module_153 www.broad.mit.e...
Broad module_95 View Gene Set 0.01291 490 0.04924 119 Genes in module_95 www.broad.mit.e...

Gene Set Collection: Broad.c5.BP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad SYSTEM_PROCESS View Gene Set 2.412e-15 558 1.99e-12 1 Genes annotated by the GO term GO:0003008. A biological process occurring at the level of an organ system pertinent to the function of the organism. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. www.broad.mit.e...
Broad SYSTEM_DEVELOPMENT View Gene Set 9.912e-14 853 4.089e-11 2 Genes annotated by the GO term GO:0048731. The process whose specific outcome is the progression of an organismal system over time from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. www.broad.mit.e...
Broad ANATOMICAL_STRUCTURE_DEVELOPMENT View Gene Set 1.543e-13 1004 4.243e-11 3 Genes annotated by the GO term GO:0048856. The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel or microscopic such as an acrosome. www.broad.mit.e...
Broad MULTICELLULAR_ORGANISMAL_DEVELOPMENT View Gene Set 3.828e-13 1037 7.896e-11 4 Genes annotated by the GO term GO:0007275. The biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). www.broad.mit.e...
Broad CELL_SURFACE_RECEPTOR_LINKED_SIGNAL_TRANSDUCTION_GO_0007166 View Gene Set 1.96e-12 620 3.233e-10 5 Genes annotated by the GO term GO:0007166. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell. www.broad.mit.e...
Broad CELL_CELL_SIGNALING View Gene Set 4.073e-12 400 5.601e-10 6 Genes annotated by the GO term GO:0007267. Any process that mediates the transfer of information from one cell to another. www.broad.mit.e...
Broad G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY View Gene Set 5.956e-11 326 7.02e-09 7 Genes annotated by the GO term GO:0007186. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand. www.broad.mit.e...
Broad DEFENSE_RESPONSE View Gene Set 6.119e-10 264 6.31e-08 8 Genes annotated by the GO term GO:0006952. Reactions triggered in response to the presence of a foreign body or the occurrence of an injury which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. www.broad.mit.e...
Broad NEUROLOGICAL_SYSTEM_PROCESS View Gene Set 5.431e-09 377 4.979e-07 9 Genes annotated by the GO term GO:0050877. The processes pertaining to the functions of the nervous system of an organism. www.broad.mit.e...
Broad IMMUNE_RESPONSE View Gene Set 3.193e-08 232 2.634e-06 10 Genes annotated by the GO term GO:0006955. Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. www.broad.mit.e...
Broad IMMUNE_SYSTEM_PROCESS View Gene Set 3.97e-08 326 2.755e-06 11 Genes annotated by the GO term GO:0002376. Any process involved in the development or functioning of the immune system an organismal system for calibrated responses to potential internal or invasive threats. www.broad.mit.e...
Broad RESPONSE_TO_EXTERNAL_STIMULUS View Gene Set 4.007e-08 305 2.755e-06 11 Genes annotated by the GO term GO:0009605. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of an external stimulus. www.broad.mit.e...
Broad ORGAN_DEVELOPMENT View Gene Set 4.447e-08 567 2.822e-06 13 Genes annotated by the GO term GO:0048513. Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time from its formation to the mature structure. Organs are commonly observed as visibly distinct structures but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. www.broad.mit.e...
Broad NERVOUS_SYSTEM_DEVELOPMENT View Gene Set 3.196e-07 380 1.883e-05 14 Genes annotated by the GO term GO:0007399. The process whose specific outcome is the progression of nervous tissue over time from its formation to its mature state. www.broad.mit.e...
Broad RESPONSE_TO_WOUNDING View Gene Set 2.275e-06 184 0.0001125 15 Genes annotated by the GO term GO:0009611. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus indicating damage to the organism. www.broad.mit.e...
Broad MONOVALENT_INORGANIC_CATION_TRANSPORT View Gene Set 2.319e-06 92 0.0001125 15 Genes annotated by the GO term GO:0015672. The directed movement of inorganic cations with a valency of one into out of within or between cells. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage. www.broad.mit.e...
Broad POTASSIUM_ION_TRANSPORT View Gene Set 2.116e-06 58 0.0001125 15 Genes annotated by the GO term GO:0006813. The directed movement of potassium ions (K+) into out of within or between cells. www.broad.mit.e...
Broad REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS View Gene Set 2.505e-06 149 0.0001148 18 Genes annotated by the GO term GO:0051239. Any process that modulates the frequency rate or extent of an organismal process the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. www.broad.mit.e...
Broad METAL_ION_TRANSPORT View Gene Set 7.114e-06 116 0.0003089 19 Genes annotated by the GO term GO:0030001. The directed movement of metal ions any metal ion with an electric charge into out of within or between cells. www.broad.mit.e...
Broad SYNAPTIC_TRANSMISSION View Gene Set 9.13e-06 172 0.0003766 20 Genes annotated by the GO term GO:0007268. The process of communication from a neuron to a target (neuron muscle or secretory cell) across a synapse. www.broad.mit.e...
Broad SENSORY_PERCEPTION View Gene Set 1.351e-05 190 0.0005306 21 Genes annotated by the GO term GO:0007600. The series of events required for an organism to receive a sensory stimulus convert it to a molecular signal and recognize and characterize the signal. www.broad.mit.e...
Broad ION_TRANSPORT View Gene Set 1.647e-05 183 0.0006175 22 Genes annotated by the GO term GO:0006811. The directed movement of charged atoms or small charged molecules into out of within or between cells. www.broad.mit.e...
Broad BEHAVIOR View Gene Set 1.849e-05 148 0.0006634 23 Genes annotated by the GO term GO:0007610. The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. www.broad.mit.e...
Broad CATION_TRANSPORT View Gene Set 2.574e-05 145 0.0008849 24 Genes annotated by the GO term GO:0006812. The directed movement of cations atoms or small molecules with a net positive charge into out of within or between cells. www.broad.mit.e...
Broad CHEMICAL_HOMEOSTASIS View Gene Set 3.501e-05 151 0.001155 25 Genes annotated by the GO term GO:0048878. The biological processes involved in the maintenance of an internal equilibrium of a chemical. www.broad.mit.e...
Broad REGULATION_OF_BIOLOGICAL_QUALITY View Gene Set 3.971e-05 406 0.001213 26 Genes annotated by the GO term GO:0065008. Any process that modulates the frequency rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism such as size mass shape color etc. www.broad.mit.e...
Broad ANATOMICAL_STRUCTURE_MORPHOGENESIS View Gene Set 3.843e-05 375 0.001213 26 Genes annotated by the GO term GO:0009653. The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. www.broad.mit.e...
Broad SIGNAL_TRANSDUCTION View Gene Set 4.745e-05 1597 0.001398 28 Genes annotated by the GO term GO:0007165. The cascade of processes by which a signal interacts with a receptor causing a change in the level or activity of a second messenger or other downstream target and ultimately effecting a change in the functioning of the cell. www.broad.mit.e...
Broad SECOND_MESSENGER_MEDIATED_SIGNALING View Gene Set 5.75e-05 146 0.001636 29 Genes annotated by the GO term GO:0019932. A series of molecular signals in which an ion or small molecule is formed or released into the cytosol thereby helping relay the signal within the cell. www.broad.mit.e...
Broad G_PROTEIN_SIGNALING_COUPLED_TO_CAMP_NUCLEOTIDE_SECOND_MESSENGER View Gene Set 0.0001032 64 0.002838 30 Genes annotated by the GO term GO:0007188. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand followed by modulation of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP. www.broad.mit.e...
Broad CELLULAR_HOMEOSTASIS View Gene Set 0.000122 141 0.003247 31 Genes annotated by the GO term GO:0019725. The processes involved in the maintenance of an internal equilibrium at the level of the cell. www.broad.mit.e...
Broad ION_HOMEOSTASIS View Gene Set 0.0001339 124 0.003348 32 Genes annotated by the GO term GO:0050801. Any of the processes involved in the maintenance of an internal equilibrium of ions within an organism or cell. www.broad.mit.e...
Broad TRANSMISSION_OF_NERVE_IMPULSE View Gene Set 0.0001315 187 0.003348 32 Genes annotated by the GO term GO:0019226. The sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation. www.broad.mit.e...
Broad HOMEOSTATIC_PROCESS View Gene Set 0.0001871 202 0.00454 34 Genes annotated by the GO term GO:0042592. The biological processes involved in the maintenance of an internal equilibrium. www.broad.mit.e...
Broad INFLAMMATORY_RESPONSE View Gene Set 0.0002041 124 0.004811 35 Genes annotated by the GO term GO:0006954. The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. www.broad.mit.e...
Broad CAMP_MEDIATED_SIGNALING View Gene Set 0.0002394 65 0.005486 36 Genes annotated by the GO term GO:0019933. A series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. www.broad.mit.e...
Broad REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY View Gene Set 0.000301 23 0.006712 37 Genes annotated by the GO term GO:0008277. Any process that modulates the frequency rate or extent of G-protein coupled receptor protein signaling pathway activity. www.broad.mit.e...
Broad CELL_ACTIVATION View Gene Set 0.0003205 74 0.006958 38 Genes annotated by the GO term GO:0001775. A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. www.broad.mit.e...
Broad G_PROTEIN_SIGNALING_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER View Gene Set 0.0003334 98 0.007053 39 Genes annotated by the GO term GO:0007187. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand followed by modulation of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide. www.broad.mit.e...
Broad LIPID_HOMEOSTASIS View Gene Set 0.0003662 17 0.007553 40 Genes annotated by the GO term GO:0055088. Any of the processes involved in the maintenance of an internal equilibrium of lipid within an organism or cell. www.broad.mit.e...
Broad ORGAN_MORPHOGENESIS View Gene Set 0.000483 144 0.009718 41 Genes annotated by the GO term GO:0009887. Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. www.broad.mit.e...
Broad RESPONSE_TO_BACTERIUM View Gene Set 0.0005413 30 0.01063 42 Genes annotated by the GO term GO:0009617. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus from a bacterium. www.broad.mit.e...
Broad G_PROTEIN_SIGNALING_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY View Gene Set 0.0005746 25 0.01102 43 Genes annotated by the GO term GO:0007189. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand followed by activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP. www.broad.mit.e...
Broad LOCOMOTORY_BEHAVIOR View Gene Set 0.0006405 91 0.01174 44 Genes annotated by the GO term GO:0007626. The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. www.broad.mit.e...
Broad CDC42_PROTEIN_SIGNAL_TRANSDUCTION View Gene Set 0.0006292 13 0.01174 44 Genes annotated by the GO term GO:0032488. A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. www.broad.mit.e...
Broad DETECTION_OF_STIMULUS View Gene Set 0.0007275 47 0.01305 46 Genes annotated by the GO term GO:0051606. The series of events in which a stimulus is received by a cell and converted into a molecular signal. www.broad.mit.e...
Broad DEFENSE_RESPONSE_TO_BACTERIUM View Gene Set 0.0007517 24 0.0132 47 Genes annotated by the GO term GO:0042742. Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. www.broad.mit.e...
Broad LEUKOCYTE_ACTIVATION View Gene Set 0.0008493 67 0.01459 48 Genes annotated by the GO term GO:0045321. A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen mitogen cytokine cellular ligand or soluble factor. www.broad.mit.e...
Broad DETECTION_OF_EXTERNAL_STIMULUS View Gene Set 0.0008663 23 0.01459 48 Genes annotated by the GO term GO:0009581. The series of events in which an external stimulus is received by a cell and converted into a molecular signal. www.broad.mit.e...
Broad CYTOKINE_PRODUCTION View Gene Set 0.0009522 72 0.01571 50 Genes annotated by the GO term GO:0001816. The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus resulting in an increase in its intracellular or extracellular levels. www.broad.mit.e...
Broad CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING View Gene Set 0.001002 100 0.01621 51 Genes annotated by the GO term GO:0019935. A series of molecular signals in which a cell uses a cyclic nucleotide to convert an extracellular signal into a response. www.broad.mit.e...
Broad NEURON_DIFFERENTIATION View Gene Set 0.001069 76 0.01697 52 Genes annotated by the GO term GO:0030182. The process whereby a relatively unspecialized cell acquires specialized features of a neuron. www.broad.mit.e...
Broad CELL_CELL_ADHESION View Gene Set 0.001093 86 0.01701 53 Genes annotated by the GO term GO:0016337. The attachment of one cell to another cell via adhesion molecules. www.broad.mit.e...
Broad GENERATION_OF_NEURONS View Gene Set 0.00135 83 0.02063 54 Genes annotated by the GO term GO:0048699. The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. www.broad.mit.e...
Broad NEURITE_DEVELOPMENT View Gene Set 0.001431 53 0.02124 55 Genes annotated by the GO term GO:0031175. The process whose specific outcome is the progression of the neurite over time from its formation to the mature structure. The neurite is any process extending from a neural cell such as axons or dendrites. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS View Gene Set 0.001442 66 0.02124 55 Genes annotated by the GO term GO:0051240. Any process that activates or increases the frequency rate or extent of an organismal process the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. www.broad.mit.e...
Broad CELLULAR_MORPHOGENESIS_DURING_DIFFERENTIATION View Gene Set 0.00157 49 0.02273 57 Genes annotated by the GO term GO:0000904. The change in form (cell shape and size) that occurs when relatively unspecialized cells e.g. embryonic or regenerative cells acquire specialized structural and/or functional features that characterize the cells tissues or organs of the mature organism or some other relatively stable phase of the organism's life history. www.broad.mit.e...
Broad TISSUE_DEVELOPMENT View Gene Set 0.001629 137 0.02318 58 Genes annotated by the GO term GO:0009888. The process whose specific outcome is the progression of a tissue over time from its formation to the mature structure. www.broad.mit.e...
Broad MULTI_ORGANISM_PROCESS View Gene Set 0.001723 161 0.02376 59 Genes annotated by the GO term GO:0051704. The processes by which an organism has an effect on another organism of the same or different species. www.broad.mit.e...
Broad CELLULAR_DEFENSE_RESPONSE View Gene Set 0.001728 57 0.02376 59 Genes annotated by the GO term GO:0006968. A defense response that is mediated by cells. www.broad.mit.e...
Broad NEURON_DEVELOPMENT View Gene Set 0.002286 61 0.03091 61 Genes annotated by the GO term GO:0048666. The process whose specific outcome is the progression of a neuron over time from initial commitment of the cell to a specific fate to the fully functional differentiated cell. www.broad.mit.e...
Broad INTERLEUKIN_1_SECRETION View Gene Set 0.002433 10 0.03188 62 Genes annotated by the GO term GO:0050701. The regulated release of interleukin-1 from a cell or group of cells. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation by inducing interleukin 2 release and it is involved in the inflammatory response. www.broad.mit.e...
Broad CATION_HOMEOSTASIS View Gene Set 0.002435 104 0.03188 62 Genes annotated by the GO term GO:0055080. The regulation of the levels transport and metabolism of cations. www.broad.mit.e...
Broad REGULATION_OF_SECRETION View Gene Set 0.002476 40 0.03192 64 Genes annotated by the GO term GO:0051046. Any process that modulates the frequency rate or extent of the regulated release of a substance from a cell or group of cells. www.broad.mit.e...
Broad WOUND_HEALING View Gene Set 0.002574 53 0.03218 65 Genes annotated by the GO term GO:0042060. The series of events that restore integrity to a damaged tissue following an injury. www.broad.mit.e...
Broad ADENYLATE_CYCLASE_ACTIVATION View Gene Set 0.002545 19 0.03218 65 Genes annotated by the GO term GO:0007190. Any process that initiates the activity of the inactive enzyme adenylate cyclase. www.broad.mit.e...
Broad RESPONSE_TO_OTHER_ORGANISM View Gene Set 0.002709 80 0.03336 67 Genes annotated by the GO term GO:0051707. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus from another living organism. www.broad.mit.e...
Broad HUMORAL_IMMUNE_RESPONSE View Gene Set 0.002843 31 0.03449 68 Genes annotated by the GO term GO:0006959. An immune response mediated through a body fluid. www.broad.mit.e...
Broad CYTOKINE_SECRETION View Gene Set 0.003023 18 0.03615 69 Genes annotated by the GO term GO:0050663. The regulated release of cytokines from a cell or group of cells. Cytokines are any of a group of proteins that function to control the survival growth and differentiation of tissues and cells and which have autocrine and paracrine activity. www.broad.mit.e...
Broad REGULATION_OF_CYTOKINE_SECRETION View Gene Set 0.003254 16 0.03835 70 Genes annotated by the GO term GO:0050707. Any process that modulates the frequency rate or extent of the regulated release of cytokines from a cell or group of cells. www.broad.mit.e...
Broad SKELETAL_DEVELOPMENT View Gene Set 0.00344 102 0.03997 71 Genes annotated by the GO term GO:0001501. The process whose specific outcome is the progression of the skeleton over time from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). www.broad.mit.e...
Broad AXONOGENESIS View Gene Set 0.003634 43 0.04107 72 Genes annotated by the GO term GO:0007409. Generation of a long process of a neuron that carries efferent (outgoing) action potentials from the cell body towards target cells. www.broad.mit.e...
Broad LYMPHOCYTE_ACTIVATION View Gene Set 0.003613 60 0.04107 72 Genes annotated by the GO term GO:0046649. A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen mitogen cytokine chemokine cellular ligand or soluble factor. www.broad.mit.e...
Broad MUSCLE_DEVELOPMENT View Gene Set 0.004072 92 0.04539 74 Genes annotated by the GO term GO:0007517. The process whose specific outcome is the progression of the muscle over time from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. www.broad.mit.e...
Broad ANATOMICAL_STRUCTURE_FORMATION View Gene Set 0.004319 56 0.04751 75 Genes annotated by the GO term GO:0048646. The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel or microscopic such as an acrosome. www.broad.mit.e...

Gene Set Collection: Broad.c5.CC

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad EXTRACELLULAR_REGION View Gene Set 1.104e-17 437 2.572e-15 1 Genes annotated by the GO term GO:0005576. The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. www.broad.mit.e...
Broad PLASMA_MEMBRANE_PART View Gene Set 4.368e-16 1142 4.483e-14 2 Genes annotated by the GO term GO:0044459. Any constituent part of the plasma membrane the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. www.broad.mit.e...
Broad PLASMA_MEMBRANE View Gene Set 5.772e-16 1392 4.483e-14 2 Genes annotated by the GO term GO:0005886. The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. www.broad.mit.e...
Broad INTRINSIC_TO_PLASMA_MEMBRANE View Gene Set 1.025e-14 978 4.778e-13 4 Genes annotated by the GO term GO:0031226. Located in the plasma membrane such that some covalently attached portion of the gene product for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor spans or is embedded in one or both leaflets of the membrane. www.broad.mit.e...
Broad EXTRACELLULAR_REGION_PART View Gene Set 1.019e-14 331 4.778e-13 4 Genes annotated by the GO term GO:0044421. Any constituent part of the extracellular region the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite. www.broad.mit.e...
Broad INTEGRAL_TO_PLASMA_MEMBRANE View Gene Set 3.047e-14 964 1.183e-12 6 Genes annotated by the GO term GO:0005887. Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. www.broad.mit.e...
Broad INTRINSIC_TO_MEMBRANE View Gene Set 7.273e-11 1319 2.118e-09 7 Genes annotated by the GO term GO:0031224. Located in a membrane such that some covalently attached portion of the gene product for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor spans or is embedded in one or both leaflets of the membrane. www.broad.mit.e...
Broad EXTRACELLULAR_SPACE View Gene Set 6.934e-11 239 2.118e-09 7 Genes annotated by the GO term GO:0005615. That part of a multicellular organism outside the cells proper usually taken to be outside the plasma membranes and occupied by fluid. www.broad.mit.e...
Broad INTEGRAL_TO_MEMBRANE View Gene Set 2.046e-10 1301 5.296e-09 9 Genes annotated by the GO term GO:0016021. Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein indicates that all or part of the peptide sequence is embedded in the membrane. www.broad.mit.e...
Broad PROTEINACEOUS_EXTRACELLULAR_MATRIX View Gene Set 1.18e-06 98 2.749e-05 10 Genes annotated by the GO term GO:0005578. A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. www.broad.mit.e...
Broad EXTRACELLULAR_MATRIX View Gene Set 2.608e-06 100 5.524e-05 11 Genes annotated by the GO term GO:0031012. A structure lying external to one or more cells which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants). www.broad.mit.e...
Broad MEMBRANE_PART View Gene Set 9.069e-06 1632 0.0001761 12 Genes annotated by the GO term GO:0044425. Any constituent part of a membrane a double layer of lipid molecules that encloses all cells and in eukaryotes many organelles; may be a single or double lipid bilayer; also includes associated proteins. www.broad.mit.e...
Broad VOLTAGE_GATED_POTASSIUM_CHANNEL_COMPLEX View Gene Set 1.386e-05 40 0.0002484 13 Genes annotated by the GO term GO:0008076. A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential. www.broad.mit.e...
Broad COLLAGEN View Gene Set 1.516e-05 23 0.0002524 14 Genes annotated by the GO term GO:0005581. Any of the various assemblies in which collagen chains form a left-handed triple helix; may assemble into higher order structures. www.broad.mit.e...
Broad MEMBRANE View Gene Set 2.125e-05 1939 0.00033 15 Genes annotated by the GO term GO:0016020. Double layer of lipid molecules that encloses all cells and in eukaryotes many organelles; may be a single or double lipid bilayer; also includes associated proteins. www.broad.mit.e...
Broad EXTRACELLULAR_MATRIX_PART View Gene Set 0.0004205 57 0.006124 16 Genes annotated by the GO term GO:0044420. Any constituent part of the extracellular matrix the structure lying external to one or more cells which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants). www.broad.mit.e...
Broad VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX View Gene Set 0.003291 15 0.04511 17 Genes annotated by the GO term GO:0005891. A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential. www.broad.mit.e...

Gene Set Collection: Broad.c5.MF

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad TRANSMEMBRANE_RECEPTOR_ACTIVITY View Gene Set 3.566e-12 411 1.412e-09 1 Genes annotated by the GO term GO:0004888. Combining with an extracellular or intracellular messenger to initiate a change in cell activity and spanning to the membrane of either the cell or an organelle. www.broad.mit.e...
Broad RECEPTOR_ACTIVITY View Gene Set 1.221e-11 572 2.418e-09 2 Genes annotated by the GO term GO:0004872. Combining with an extracellular or intracellular messenger to initiate a change in cell activity. www.broad.mit.e...
Broad SUBSTRATE_SPECIFIC_CHANNEL_ACTIVITY View Gene Set 9.254e-11 154 9.161e-09 3 Genes annotated by the GO term GO:0022838. Catalysis of energy-independent facilitated diffusion mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules. www.broad.mit.e...
Broad ION_CHANNEL_ACTIVITY View Gene Set 8.442e-11 147 9.161e-09 3 Genes annotated by the GO term GO:0005216. Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. www.broad.mit.e...
Broad GATED_CHANNEL_ACTIVITY View Gene Set 1.868e-09 121 1.48e-07 5 Genes annotated by the GO term GO:0022836. Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus. www.broad.mit.e...
Broad CATION_CHANNEL_ACTIVITY View Gene Set 7.609e-09 118 5.022e-07 6 Genes annotated by the GO term GO:0005261. Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient. www.broad.mit.e...
Broad VOLTAGE_GATED_CHANNEL_ACTIVITY View Gene Set 9.502e-08 73 5.376e-06 7 Genes annotated by the GO term GO:0022832. Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded. www.broad.mit.e...
Broad METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY View Gene Set 1.363e-07 145 6.746e-06 8 Genes annotated by the GO term GO:0046873. Catalysis of the transfer of metal ions from one side of a membrane to the other. www.broad.mit.e...
Broad VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY View Gene Set 1.645e-07 66 7.237e-06 9 Genes annotated by the GO term GO:0022843. Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. www.broad.mit.e...
Broad ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY View Gene Set 5.122e-07 275 2.028e-05 10 Genes annotated by the GO term GO:0015075. Catalysis of the transfer of an ion from one side of a membrane to the other. www.broad.mit.e...
Broad G_PROTEIN_COUPLED_RECEPTOR_ACTIVITY View Gene Set 7.045e-07 185 2.536e-05 11 Genes annotated by the GO term GO:0004930. A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers. www.broad.mit.e...
Broad RECEPTOR_BINDING View Gene Set 3.368e-06 373 0.0001111 12 Genes annotated by the GO term GO:0005102. Interacting selectively with one or more specific sites on a receptor molecule a macromolecule that undergoes combination with a hormone neurotransmitter drug or intracellular messenger to initiate a change in cell function. www.broad.mit.e...
Broad GROWTH_FACTOR_ACTIVITY View Gene Set 4.376e-06 54 0.0001333 13 Genes annotated by the GO term GO:0008083. The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation. www.broad.mit.e...
Broad POTASSIUM_CHANNEL_ACTIVITY View Gene Set 1.013e-05 50 0.0002865 14 Genes annotated by the GO term GO:0005267. Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. www.broad.mit.e...
Broad VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY View Gene Set 1.379e-05 36 0.0003639 15 Genes annotated by the GO term GO:0005249. Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel. www.broad.mit.e...
Broad CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY View Gene Set 2.252e-05 211 0.0005574 16 Genes annotated by the GO term GO:0008324. Catalysis of the transfer of cation from one side of the membrane to the other. www.broad.mit.e...
Broad RHODOPSIN_LIKE_RECEPTOR_ACTIVITY View Gene Set 5.428e-05 131 0.001264 17 Genes annotated by the GO term GO:0001584. A G-protein coupled receptor that is structurally/functionally related to the rhodopsin receptor. www.broad.mit.e...
Broad CYTOKINE_ACTIVITY View Gene Set 9.238e-05 111 0.002032 18 Genes annotated by the GO term GO:0005125. Functions to control the survival growth differentiation and effector function of tissues and cells. www.broad.mit.e...
Broad HORMONE_ACTIVITY View Gene Set 0.000276 44 0.005753 19 Genes annotated by the GO term GO:0005179. The action characteristic of a hormone any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants and to synthetic substances having comparable effects. www.broad.mit.e...
Broad SUBSTRATE_SPECIFIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY View Gene Set 0.0007738 341 0.01532 20 Genes annotated by the GO term GO:0022891. Catalysis of the transfer of a specific substance or group of related substances from one side of a membrane to the other. www.broad.mit.e...
Broad G_PROTEIN_COUPLED_RECEPTOR_BINDING View Gene Set 0.0009546 54 0.018 21 Genes annotated by the GO term GO:0001664. Interacting selectively with a G-protein-coupled receptor. www.broad.mit.e...
Broad SERINE_TYPE_ENDOPEPTIDASE_ACTIVITY View Gene Set 0.001195 39 0.02151 22 Genes annotated by the GO term GO:0004252. Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). www.broad.mit.e...
Broad INTEGRIN_BINDING View Gene Set 0.001448 30 0.02366 23 Genes annotated by the GO term GO:0005178. Interacting selectively with an integrin. www.broad.mit.e...
Broad SUBSTRATE_SPECIFIC_TRANSPORTER_ACTIVITY View Gene Set 0.001535 389 0.02366 23 Genes annotated by the GO term GO:0022892. Enables the directed movement of a specific substance or group of related substances (such as macromolecules small molecules ions) into out of within or between cells. www.broad.mit.e...
Broad SERINE_HYDROLASE_ACTIVITY View Gene Set 0.001418 44 0.02366 23 Genes annotated by the GO term GO:0017171. Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). www.broad.mit.e...
Broad TRANSMEMBRANE_TRANSPORTER_ACTIVITY View Gene Set 0.001553 371 0.02366 23 Genes annotated by the GO term GO:0022857. Catalysis of the transfer of a substance from one side of a membrane to the other. www.broad.mit.e...
Broad CARBOHYDRATE_BINDING View Gene Set 0.001769 72 0.0253 27 Genes annotated by the GO term GO:0030246. Interacting selectively with any carbohydrate. www.broad.mit.e...
Broad VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY View Gene Set 0.001832 18 0.0253 27 Genes annotated by the GO term GO:0005245. Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel. www.broad.mit.e...
Broad DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY View Gene Set 0.001853 12 0.0253 27 Genes annotated by the GO term GO:0005251. www.broad.mit.e...
Broad SERINE_TYPE_PEPTIDASE_ACTIVITY View Gene Set 0.00207 43 0.02732 30 Genes annotated by the GO term GO:0008236. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). www.broad.mit.e...
Broad CHEMOKINE_RECEPTOR_BINDING View Gene Set 0.002627 43 0.03356 31 Genes annotated by the GO term GO:0042379. Interacting selectively with any chemokine receptor. www.broad.mit.e...
Broad NEUROPEPTIDE_HORMONE_ACTIVITY View Gene Set 0.002716 12 0.03362 32 Genes annotated by the GO term GO:0005184. The action characteristic of a neuropeptide hormone any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue composed of short chains of amino acids; they include endorphins enkephalins vasopressin and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters although some are also hormones. www.broad.mit.e...
Broad CHEMOKINE_ACTIVITY View Gene Set 0.00305 42 0.03553 33 Genes annotated by the GO term GO:0008009. The function of a family of chemotactic pro-inflammatory activation-inducible cytokines acting primarily upon hemopoietic cells in immunoregulatory processes; all chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. www.broad.mit.e...
Broad CALCIUM_CHANNEL_ACTIVITY View Gene Set 0.002985 33 0.03553 33 Genes annotated by the GO term GO:0005262. Catalysis of facilitated diffusion of an calcium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. www.broad.mit.e...
Broad LIGAND_GATED_CHANNEL_ACTIVITY View Gene Set 0.003193 39 0.03612 35 Genes annotated by the GO term GO:0022834. Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. www.broad.mit.e...
Broad HEMATOPOIETIN_INTERFERON_CLASSD200_DOMAIN_CYTOKINE_RECEPTOR_BINDING View Gene Set 0.004344 29 0.04778 36 Genes annotated by the GO term GO:0005126. www.broad.mit.e...

Gene Set Collection: PMID

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
PMID 12975309 View Gene Set 4.523e-13 1000 1.134e-09 1 The secreted protein discovery initiative (SPDI) a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. www.ncbi.nlm.ni...
PMID 20452482 View Gene Set 4.674e-11 188 5.859e-08 2 Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. www.ncbi.nlm.ni...
PMID 20237496 View Gene Set 9.431e-11 828 7.881e-08 3 New genetic associations detected in a host response study to hepatitis B vaccine. www.ncbi.nlm.ni...
PMID 15340161 View Gene Set 1.34e-09 264 8.4e-07 4 Signal peptide prediction based on analysis of experimentally verified cleavage sites. www.ncbi.nlm.ni...
PMID 19086053 View Gene Set 2.4e-09 301 1.204e-06 5 Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. www.ncbi.nlm.ni...
PMID 20503287 View Gene Set 1.796e-08 205 7.506e-06 6 Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. www.ncbi.nlm.ni...
PMID 17703412 View Gene Set 2.521e-08 207 9.03e-06 7 Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. www.ncbi.nlm.ni...
PMID 19258923 View Gene Set 4.271e-08 205 1.338e-05 8 Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. www.ncbi.nlm.ni...
PMID 16335952 View Gene Set 5.8e-08 257 1.616e-05 9 Human plasma N-glycoproteome analysis by immunoaffinity subtraction hydrazide chemistry and mass spectrometry. www.ncbi.nlm.ni...
PMID 20424473 View Gene Set 6.737e-08 146 1.689e-05 10 L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms. www.ncbi.nlm.ni...
PMID 18240029 View Gene Set 2.415e-07 203 5.505e-05 11 Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. www.ncbi.nlm.ni...
PMID 19419973 View Gene Set 3.596e-07 13 7.512e-05 12 Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia. www.ncbi.nlm.ni...
PMID 12679517 View Gene Set 4.913e-07 31 9.475e-05 13 The G protein-coupled receptor repertoires of human and mouse. www.ncbi.nlm.ni...
PMID 10836148 View Gene Set 7.775e-07 14 0.0001147 14 Human UDP-glucuronosyltransferases: metabolism expression and disease. www.ncbi.nlm.ni...
PMID 11434514 View Gene Set 7.775e-07 12 0.0001147 14 Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus. www.ncbi.nlm.ni...
PMID 11465080 View Gene Set 7.775e-07 10 0.0001147 14 UDP-glucuronosyltransferases. www.ncbi.nlm.ni...
PMID 14983052 View Gene Set 6.491e-07 391 0.0001147 14 The human olfactory receptor gene family. www.ncbi.nlm.ni...
PMID 2286373 View Gene Set 9.466e-07 12 0.0001318 18 Human metallothionein genes: structure of the functional locus at 16q13. www.ncbi.nlm.ni...
PMID 18834073 View Gene Set 1.114e-06 18 0.000147 19 Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux. www.ncbi.nlm.ni...
PMID 19453261 View Gene Set 1.478e-06 383 0.0001852 20 High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. www.ncbi.nlm.ni...
PMID 8084338 View Gene Set 1.973e-06 21 0.0002355 21 HIV-1 gp41 binding proteins and antibodies to gp41 could inhibit enhancement of human Raji cell MHC class I and II expression by gp41. www.ncbi.nlm.ni...
PMID 9295054 View Gene Set 2.794e-06 14 0.0003183 22 The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. www.ncbi.nlm.ni...
PMID 19420105 View Gene Set 3.55e-06 81 0.0003869 23 A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN). www.ncbi.nlm.ni...
PMID 12427289 View Gene Set 4.548e-06 20 0.0004751 24 HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells. www.ncbi.nlm.ni...
PMID 19247692 View Gene Set 5.149e-06 92 0.0005164 25 Analyses of associations with asthma in four asthma population samples from Canada and Australia. www.ncbi.nlm.ni...
PMID 19948975 View Gene Set 5.53e-06 229 0.0005333 26 Integrative predictive model of coronary artery calcification in atherosclerosis. www.ncbi.nlm.ni...
PMID 14672974 View Gene Set 9.701e-06 12 0.0009008 27 Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation. www.ncbi.nlm.ni...
PMID 17652306 View Gene Set 1.104e-05 28 0.0009889 28 Keeping the (kinase) party going: SLP-76 and ITK dance to the beat. www.ncbi.nlm.ni...
PMID 11048639 View Gene Set 1.162e-05 29 0.001004 29 The mechanism of phospholipase C-gamma1 regulation. www.ncbi.nlm.ni...
PMID 7539755 View Gene Set 1.401e-05 21 0.001171 30 Modulation of CD4 lateral interaction with lymphocyte surface molecules induced by HIV-1 gp120. www.ncbi.nlm.ni...
PMID 19578796 View Gene Set 3.64e-05 152 0.002944 31 Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. www.ncbi.nlm.ni...
PMID 19336475 View Gene Set 4.016e-05 76 0.003146 32 Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk. www.ncbi.nlm.ni...
PMID 19263529 View Gene Set 4.708e-05 57 0.003576 33 Genetic risk factors in recurrent venous thromboembolism: A multilocus population-based prospective approach. www.ncbi.nlm.ni...
PMID 12815422 View Gene Set 4.997e-05 239 0.003685 34 The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. www.ncbi.nlm.ni...
PMID 16382104 View Gene Set 5.599e-05 40 0.004011 35 International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. www.ncbi.nlm.ni...
PMID 19736351 View Gene Set 6.533e-05 31 0.00455 36 Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia autism and mental retardation. www.ncbi.nlm.ni...
PMID 11827988 View Gene Set 6.874e-05 25 0.004658 37 Adapters in lymphocyte signaling. www.ncbi.nlm.ni...
PMID 1973146 View Gene Set 9.032e-05 43 0.005793 38 Nomenclature for human homeobox genes. www.ncbi.nlm.ni...
PMID 20082482 View Gene Set 9.243e-05 29 0.005793 38 Immunogenetic characteristics of patients with autoimmune gastritis. www.ncbi.nlm.ni...
PMID 9263011 View Gene Set 9.041e-05 20 0.005793 38 gp 120s derived from four syncytium-inducing HIV-1 strains induce different patterns of CD4 association with lymphocyte surface molecules. www.ncbi.nlm.ni...
PMID 19131662 View Gene Set 9.583e-05 64 0.00586 41 A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. www.ncbi.nlm.ni...
PMID 19861144 View Gene Set 0.0001041 21 0.005933 42 Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis. www.ncbi.nlm.ni...
PMID 20426625 View Gene Set 0.0001008 20 0.005933 42 HLA and KIR frequencies in Sicilian Centenarians. www.ncbi.nlm.ni...
PMID 20492596 View Gene Set 0.0001041 22 0.005933 42 Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3). www.ncbi.nlm.ni...
PMID 7913356 View Gene Set 0.0001103 13 0.006146 45 HIV-1 gp41 enhances major histocompatibility complex class I and ICAM-1 expression on H9 and U937 cells. www.ncbi.nlm.ni...
PMID 15128046 View Gene Set 0.0001143 60 0.006231 46 Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes including nomenclature recommendations for genes pseudogenes and alternative-splice variants. www.ncbi.nlm.ni...
PMID 19414484 View Gene Set 0.0001172 22 0.006252 47 Genome-wide association meta-analysis for total serum bilirubin levels. www.ncbi.nlm.ni...
PMID 11181995 View Gene Set 0.0001535 511 0.008018 48 The sequence of the human genome. www.ncbi.nlm.ni...
PMID 15489916 View Gene Set 0.0001721 24 0.008803 49 Function of the Src-family kinases Lck and Fyn in T-cell development and activation. www.ncbi.nlm.ni...
PMID 12446192 View Gene Set 0.0001883 15 0.008881 50 Analysis of several hundred genetic polymorphisms may improve assessment of the individual genetic burden for coronary artery disease. www.ncbi.nlm.ni...
PMID 12956878 View Gene Set 0.0001979 10 0.008881 50 Roles of HLA-B HLA-C and HLA-DPA1 incompatibilities in the outcome of unrelated stem-cell transplantation. www.ncbi.nlm.ni...
PMID 16873704 View Gene Set 0.0001904 12 0.008881 50 Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects. www.ncbi.nlm.ni...
PMID 19683555 View Gene Set 0.0001944 35 0.008881 50 Role of human leukocyte antigen killer-cell immunoglobulin-like receptors and cytokine gene polymorphisms in leptospirosis. www.ncbi.nlm.ni...
PMID 20161734 View Gene Set 0.0001896 16 0.008881 50 Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants. www.ncbi.nlm.ni...
PMID 20210918 View Gene Set 0.0001984 18 0.008881 50 Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela. www.ncbi.nlm.ni...
PMID 20237151 View Gene Set 0.0001978 12 0.008881 50 Field synopsis and synthesis of genetic association studies in osteoarthritis: the CUMAGAS-OSTEO information system. www.ncbi.nlm.ni...
PMID 10391210 View Gene Set 0.0002169 16 0.009377 57 Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. www.ncbi.nlm.ni...
PMID 1358459 View Gene Set 0.0002161 40 0.009377 57 Vertebrate homeobox gene nomenclature. www.ncbi.nlm.ni...
PMID 19630074 View Gene Set 0.0002275 18 0.009667 59 Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis. www.ncbi.nlm.ni...
PMID 18519826 View Gene Set 0.0002393 101 0.009978 60 Molecular genetics of successful smoking cessation: convergent genome-wide association study results. www.ncbi.nlm.ni...
PMID 20346360 View Gene Set 0.0002428 94 0.009978 60 Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. www.ncbi.nlm.ni...
PMID 14760718 View Gene Set 0.0002571 47 0.0104 62 Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. www.ncbi.nlm.ni...
PMID 11698679 View Gene Set 0.0002804 19 0.01057 63 Differentially expressed late constituents of the epidermal cornified envelope. www.ncbi.nlm.ni...
PMID 18571006 View Gene Set 0.0002952 19 0.01057 63 KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease. www.ncbi.nlm.ni...
PMID 18778326 View Gene Set 0.0002952 19 0.01057 63 Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil. www.ncbi.nlm.ni...
PMID 18848853 View Gene Set 0.0002952 19 0.01057 63 Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of ParanĂ¡. www.ncbi.nlm.ni...
PMID 19968064 View Gene Set 0.0002952 17 0.01057 63 [Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoitic stem cell transplantation]. www.ncbi.nlm.ni...
PMID 20173792 View Gene Set 0.0002952 17 0.01057 63 The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia. www.ncbi.nlm.ni...
PMID 20193031 View Gene Set 0.0002952 20 0.01057 63 Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay. www.ncbi.nlm.ni...
PMID 20519398 View Gene Set 0.0002952 18 0.01057 63 Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa. www.ncbi.nlm.ni...
PMID 15854049 View Gene Set 0.000301 18 0.01058 71 Late cornified envelope family in differentiating epithelia--response to calcium and ultraviolet irradiation. www.ncbi.nlm.ni...
PMID 18937294 View Gene Set 0.0003038 33 0.01058 71 Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder. www.ncbi.nlm.ni...
PMID 2576652 View Gene Set 0.0003335 22 0.01145 73 Organization of human class I homeobox genes. www.ncbi.nlm.ni...
PMID 11904677 View Gene Set 0.0003468 10 0.01175 74 Distinctive KIR and HLA diversity in a panel of north Indian Hindus. www.ncbi.nlm.ni...
PMID 18633131 View Gene Set 0.0003571 44 0.01194 75 Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era. www.ncbi.nlm.ni...
PMID 16831889 View Gene Set 0.0004169 62 0.01375 76 New consensus nomenclature for mammalian keratins. www.ncbi.nlm.ni...
PMID 11857506 View Gene Set 0.0004554 38 0.0142 77 Complete mutation analysis panel of the 39 human HOX genes. www.ncbi.nlm.ni...
PMID 16091223 View Gene Set 0.0004587 14 0.0142 77 HIV accessory proteins and surviving the host cell. www.ncbi.nlm.ni...
PMID 19336370 View Gene Set 0.0004506 130 0.0142 77 Determination of genetic predisposition to patent ductus arteriosus in preterm infants. www.ncbi.nlm.ni...
PMID 19860767 View Gene Set 0.0004491 13 0.0142 77 Genetic cardiovascular risk factors and age-related macular degeneration. www.ncbi.nlm.ni...
PMID 2574852 View Gene Set 0.0004473 29 0.0142 77 The human HOX gene family. www.ncbi.nlm.ni...
PMID 18161889 View Gene Set 0.000476 12 0.01455 82 Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis. www.ncbi.nlm.ni...
PMID 18974842 View Gene Set 0.0005322 46 0.01608 83 Gender differences in genetic risk profiles for cardiovascular disease. www.ncbi.nlm.ni...
PMID 19874574 View Gene Set 0.0005571 130 0.01624 84 Genetical genomic determinants of alcohol consumption in rats and humans. www.ncbi.nlm.ni...
PMID 19898482 View Gene Set 0.0005571 66 0.01624 84 Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. www.ncbi.nlm.ni...
PMID 20173784 View Gene Set 0.0005499 17 0.01624 84 The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population. www.ncbi.nlm.ni...
PMID 14718574 View Gene Set 0.0005703 166 0.01625 87 The human plasma proteome: a nonredundant list developed by combination of four separate sources. www.ncbi.nlm.ni...
PMID 2745554 View Gene Set 0.0005654 11 0.01625 87 SPARC a secreted protein associated with cellular proliferation inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix. www.ncbi.nlm.ni...
PMID 20468064 View Gene Set 0.0005884 182 0.01657 89 Association study of 182 candidate genes in anorexia nervosa. www.ncbi.nlm.ni...
PMID 20331834 View Gene Set 0.0006107 16 0.01682 90 Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA. www.ncbi.nlm.ni...
PMID 20483367 View Gene Set 0.0006107 16 0.01682 90 Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru. www.ncbi.nlm.ni...
PMID 19956635 View Gene Set 0.0006262 108 0.01706 92 Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies. www.ncbi.nlm.ni...
PMID 11751963 View Gene Set 0.0006861 21 0.0183 93 Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation function and antigen-specific T cell responses. www.ncbi.nlm.ni...
PMID 17632545 View Gene Set 0.0006809 10 0.0183 93 A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. www.ncbi.nlm.ni...
PMID 9242638 View Gene Set 0.0007283 14 0.01922 95 Differential interactions of Id proteins with basic-helix-loop-helix transcription factors. www.ncbi.nlm.ni...
PMID 17868255 View Gene Set 0.0007739 16 0.0198 96 No association of KIR genes with Behcet's disease. www.ncbi.nlm.ni...
PMID 18992263 View Gene Set 0.0007676 25 0.0198 96 Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways. www.ncbi.nlm.ni...
PMID 19846535 View Gene Set 0.0007739 18 0.0198 96 Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection. www.ncbi.nlm.ni...
PMID 12836198 View Gene Set 0.0008228 17 0.02084 99 [The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway]. www.ncbi.nlm.ni...
PMID 18676870 View Gene Set 0.0008893 22 0.0223 100 Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China. www.ncbi.nlm.ni...
PMID 12107411 View Gene Set 0.0008988 46 0.02231 101 Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin an abundant novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts. www.ncbi.nlm.ni...
PMID 10729169 View Gene Set 0.00101 15 0.02235 102 Efficient incorporation of HLA class II onto human immunodeficiency virus type 1 requires envelope glycoprotein packaging. www.ncbi.nlm.ni...
PMID 11543631 View Gene Set 0.0009555 12 0.02235 102 Genomic analysis of synaptotagmin genes. www.ncbi.nlm.ni...
PMID 12359730 View Gene Set 0.001034 40 0.02235 102 Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1. www.ncbi.nlm.ni...
PMID 12514663 View Gene Set 0.001022 12 0.02235 102 Potential thrombophilic mutations/polymorphisms in patients with no flow-limiting stenosis after myocardial infarction. www.ncbi.nlm.ni...
PMID 12871600 View Gene Set 0.0009603 22 0.02235 102 Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen. www.ncbi.nlm.ni...
PMID 15839736 View Gene Set 0.0009834 17 0.02235 102 Differentiation of insulin-producing cells from human neural progenitor cells. www.ncbi.nlm.ni...
PMID 16382102 View Gene Set 0.001034 10 0.02235 102 International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels. www.ncbi.nlm.ni...
PMID 19423540 View Gene Set 0.0009357 209 0.02235 102 Common variation in genes related to innate immunity and risk of adult glioma. www.ncbi.nlm.ni...
PMID 19424794 View Gene Set 0.001043 17 0.02235 102 Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women. www.ncbi.nlm.ni...
PMID 20210919 View Gene Set 0.0009094 16 0.02235 102 HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop. www.ncbi.nlm.ni...
PMID 20331378 View Gene Set 0.001043 112 0.02235 102 Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. www.ncbi.nlm.ni...
PMID 20406964 View Gene Set 0.0009357 209 0.02235 102 Risk of meningioma and common variation in genes related to innate immunity. www.ncbi.nlm.ni...
PMID 3489470 View Gene Set 0.00101 15 0.02235 102 AIDS and related syndromes as a viral-induced autoimmune disease of the immune system: an anti-MHC II disorder. Therapeutic implications. www.ncbi.nlm.ni...
PMID 7602119 View Gene Set 0.00101 15 0.02235 102 Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and role in processing for association with class II MHC. www.ncbi.nlm.ni...
PMID 8376762 View Gene Set 0.00101 15 0.02235 102 HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II-restricted T lymphocytes. www.ncbi.nlm.ni...
PMID 9079699 View Gene Set 0.00101 15 0.02235 102 The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway. www.ncbi.nlm.ni...
PMID 11140838 View Gene Set 0.001059 58 0.02249 118 A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory. www.ncbi.nlm.ni...
PMID 20200544 View Gene Set 0.001074 18 0.02263 119 Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes. www.ncbi.nlm.ni...
PMID 18564921 View Gene Set 0.001097 25 0.02273 120 Candidate gene analysis in primary lymphedema. www.ncbi.nlm.ni...
PMID 19046302 View Gene Set 0.001096 18 0.02273 120 Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians. www.ncbi.nlm.ni...
PMID 19934297 View Gene Set 0.00115 13 0.02363 122 KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma. www.ncbi.nlm.ni...
PMID 11756498 View Gene Set 0.00116 40 0.02363 123 Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis. www.ncbi.nlm.ni...
PMID 20438785 View Gene Set 0.001196 208 0.02418 124 Polymorphisms in innate immunity genes and risk of childhood leukemia. www.ncbi.nlm.ni...
PMID 16928730 View Gene Set 0.001209 11 0.02426 125 Identifying genetic susceptibilities to diabetes-related complications among individuals at low risk of complications: An application of tree-structured survival analysis. www.ncbi.nlm.ni...
PMID 19180518 View Gene Set 0.001281 25 0.02549 126 Associations of 25 structural degradative and inflammatory candidate genes with lumbar disc desiccation bulging and height narrowing. www.ncbi.nlm.ni...
PMID 19479237 View Gene Set 0.001312 57 0.02589 127 Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling. www.ncbi.nlm.ni...
PMID 19032228 View Gene Set 0.001322 17 0.0259 128 Natural killer cell receptor repertoire and their ligands and the risk of CMV infection after kidney transplantation. www.ncbi.nlm.ni...
PMID 10661406 View Gene Set 0.001384 18 0.02628 129 Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection. www.ncbi.nlm.ni...
PMID 11118314 View Gene Set 0.001384 18 0.02628 129 Reciprocal modulation of transcriptional activities between HIV-1 Tat and MHC class II transactivator CIITA. www.ncbi.nlm.ni...
PMID 19008959 View Gene Set 0.001382 12 0.02628 129 The genetics of primary haemorrhagic stroke subarachnoid haemorrhage and ruptured intracranial aneurysms in adults. www.ncbi.nlm.ni...
PMID 19169284 View Gene Set 0.001365 17 0.02628 129 KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated 12/12 HLA matched hematopoietic stem cell transplantation. www.ncbi.nlm.ni...
PMID 19559392 View Gene Set 0.001431 52 0.02697 133 A candidate gene association study of 77 polymorphisms in migraine. www.ncbi.nlm.ni...
PMID 1978941 View Gene Set 0.001502 16 0.02768 134 Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules. www.ncbi.nlm.ni...
PMID 2543930 View Gene Set 0.001502 16 0.02768 134 Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding. www.ncbi.nlm.ni...
PMID 2846691 View Gene Set 0.001502 16 0.02768 134 Inhibition of CD4+ T cell function by the HIV envelope protein gp120. www.ncbi.nlm.ni...
PMID 12376548 View Gene Set 0.001571 47 0.02875 137 NRAGE a p75 neurotrophin receptor-interacting protein induces caspase activation and cell death through a JNK-dependent mitochondrial pathway. www.ncbi.nlm.ni...
PMID 18927546 View Gene Set 0.001612 17 0.02925 138 Lp(a) and risk of recurrent cardiac events in obese postinfarction patients. www.ncbi.nlm.ni...
PMID 19544559 View Gene Set 0.001622 12 0.02925 138 Synergistic effect of HLA class II loci and cytokine gene polymorphisms on the risk of gastric cancer in Japanese patients with Helicobacter pylori infection. www.ncbi.nlm.ni...
PMID 19015224 View Gene Set 0.001768 14 0.03093 140 Polymorphisms in C2 CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss. www.ncbi.nlm.ni...
PMID 19493232 View Gene Set 0.001814 15 0.03093 140 Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia. www.ncbi.nlm.ni...
PMID 19515364 View Gene Set 0.001813 11 0.03093 140 Genetic background of lead and mercury metabolism in a group of medical students in Austria. www.ncbi.nlm.ni...
PMID 19641626 View Gene Set 0.001744 16 0.03093 140 Local network topology in human protein interaction data predicts functional association. www.ncbi.nlm.ni...
PMID 19644155 View Gene Set 0.001749 11 0.03093 140 Evaluation of the genetic background of standard-immunosuppressant-related toxicity in a cohort of 200 paediatric renal allograft recipients--a retrospective study. www.ncbi.nlm.ni...
PMID 19850842 View Gene Set 0.001814 15 0.03093 140 Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis with and without axial spondyloarthropathy. www.ncbi.nlm.ni...
PMID 20136364 View Gene Set 0.001793 16 0.03093 140 Errors and reproducibility of DNA array-based detection of allelic variants in ADME genes: PHARMAchip. www.ncbi.nlm.ni...
PMID 2649166 View Gene Set 0.001761 12 0.03093 140 A review of the molecular genetics of the human alpha-globin gene cluster. www.ncbi.nlm.ni...
PMID 7541827 View Gene Set 0.00184 20 0.03116 148 HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71). www.ncbi.nlm.ni...
PMID 11992404 View Gene Set 0.001895 10 0.03179 149 The XAGE family of cancer/testis-associated genes: alignment and expression profile in normal tissues melanoma lesions and Ewing's sarcoma. www.ncbi.nlm.ni...
PMID 16763159 View Gene Set 0.001902 15 0.03179 149 Consistent effects of genes involved in reverse cholesterol transport on plasma lipid and apolipoprotein levels in CARDIA participants. www.ncbi.nlm.ni...
PMID 12180907 View Gene Set 0.001971 12 0.03273 151 Matrilin-2 interacts with itself and with other extracellular matrix proteins. www.ncbi.nlm.ni...
PMID 11466363 View Gene Set 0.00209 10 0.03309 152 Two novel IL-1 family members IL-1 delta and IL-1 epsilon function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2. www.ncbi.nlm.ni...
PMID 12732844 View Gene Set 0.002067 40 0.03309 152 A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus. www.ncbi.nlm.ni...
PMID 14706682 View Gene Set 0.002106 10 0.03309 152 Genetic polymorphisms associated with thrombophilia and vascular disease in women with unexplained late intrauterine fetal death: a multicenter study. www.ncbi.nlm.ni...
PMID 15199049 View Gene Set 0.002112 22 0.03309 152 Functional phylogeny relates LET-756 to fibroblast growth factor 9. www.ncbi.nlm.ni...
PMID 18174230 View Gene Set 0.002068 53 0.03309 152 Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus. www.ncbi.nlm.ni...
PMID 18643961 View Gene Set 0.002072 16 0.03309 152 A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris. www.ncbi.nlm.ni...
PMID 18945962 View Gene Set 0.002092 14 0.03309 152 Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia. www.ncbi.nlm.ni...
PMID 19326408 View Gene Set 0.002072 15 0.03309 152 Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation. www.ncbi.nlm.ni...
PMID 20356536 View Gene Set 0.002072 15 0.03309 152 [Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes]. www.ncbi.nlm.ni...
PMID 15078178 View Gene Set 0.002184 19 0.03401 161 HIV/SIV escape from immune surveillance: focus on Nef. www.ncbi.nlm.ni...
PMID 1869305 View Gene Set 0.002264 14 0.03483 162 Interaction of CD4 with HLA class II antigens and HIV gp120. www.ncbi.nlm.ni...
PMID 7512597 View Gene Set 0.002264 14 0.03483 162 HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4. www.ncbi.nlm.ni...
PMID 19601998 View Gene Set 0.002281 21 0.03487 164 Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients. www.ncbi.nlm.ni...
PMID 18240903 View Gene Set 0.002299 10 0.03494 165 Pharmacogenetically relevant polymorphisms in Portugal. www.ncbi.nlm.ni...
PMID 19474452 View Gene Set 0.002549 23 0.0385 166 Perioperative genomic profiles using structure-specific oligonucleotide probes. www.ncbi.nlm.ni...
PMID 16771603 View Gene Set 0.002859 13 0.04167 167 Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population. www.ncbi.nlm.ni...
PMID 17111197 View Gene Set 0.002836 10 0.04167 167 A comprehensive analysis of 12 thrombophilic mutations and related parameters in patients with inflammatory bowel disease: data from Turkey. www.ncbi.nlm.ni...
PMID 19072566 View Gene Set 0.002836 10 0.04167 167 Prevalence of prothrombotic polymorphisms in Greece. www.ncbi.nlm.ni...
PMID 19906129 View Gene Set 0.002836 10 0.04167 167 A prospective case-control study analyzes 12 thrombophilic gene mutations in Turkish couples with recurrent pregnancy loss. www.ncbi.nlm.ni...
PMID 20425806 View Gene Set 0.002836 10 0.04167 167 Vascular at-risk genotypes and disease severity in Lebanese sickle cell disease patients. www.ncbi.nlm.ni...
PMID 9373155 View Gene Set 0.002844 10 0.04167 167 Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene. www.ncbi.nlm.ni...
PMID 15822905 View Gene Set 0.00292 17 0.04231 173 Phosphoproteomic analysis of synaptosomes from human cerebral cortex. www.ncbi.nlm.ni...
PMID 19807924 View Gene Set 0.002943 46 0.0424 174 Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. www.ncbi.nlm.ni...
PMID 12539042 View Gene Set 0.002986 45 0.04278 175 HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. www.ncbi.nlm.ni...
PMID 19571811 View Gene Set 0.00303 15 0.04315 176 Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. www.ncbi.nlm.ni...
PMID 19560472 View Gene Set 0.003068 10 0.04346 177 Clinical factors such as B-type natriuretic peptide link to factor VII endothelial NO synthase and estrogen receptor alpha polymorphism in elderly women. www.ncbi.nlm.ni...
PMID 19181658 View Gene Set 0.003103 12 0.04356 178 Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome. www.ncbi.nlm.ni...
PMID 19729601 View Gene Set 0.00311 64 0.04356 178 Candidate gene polymorphisms for ischemic stroke. www.ncbi.nlm.ni...
PMID 12213199 View Gene Set 0.003133 216 0.04364 180 DEFOG: a practical scheme for deciphering families of genes. www.ncbi.nlm.ni...
PMID 11060466 View Gene Set 0.003273 10 0.04484 181 Clustering of two fragile sites and seven homeobox genes in human chromosome region 2q31-->q32.1. www.ncbi.nlm.ni...
PMID 1967269 View Gene Set 0.003272 15 0.04484 181 HIV-gp120 can block CD4-class II MHC-mediated adhesion. www.ncbi.nlm.ni...
PMID 8168144 View Gene Set 0.003272 15 0.04484 181 Envelope glycoproteins of HIV-1 interfere with T-cell-dependent B cell differentiation: role of CD4-MHC class II interaction in the effector phase of T cell help. www.ncbi.nlm.ni...
PMID 15028290 View Gene Set 0.00339 16 0.04619 184 A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3. www.ncbi.nlm.ni...
PMID 19503597 View Gene Set 0.00353 11 0.04784 185 Meta-analysis of 28 141 individuals identifies common variants within five new loci that influence uric acid concentrations. www.ncbi.nlm.ni...
PMID 14962103 View Gene Set 0.003604 11 0.04857 186 Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21. www.ncbi.nlm.ni...
PMID 20389299 View Gene Set 0.003658 11 0.04904 187 Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism. www.ncbi.nlm.ni...
PMID 17244347 View Gene Set 0.003709 10 0.04919 188 Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. www.ncbi.nlm.ni...
PMID 20378664 View Gene Set 0.003699 26 0.04919 188 Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis. www.ncbi.nlm.ni...
PMID 12471243 View Gene Set 0.00388 20 0.04997 190 The protein kinase complement of the human genome. www.ncbi.nlm.ni...
PMID 15896204 View Gene Set 0.004182 14 0.04997 190 Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population. www.ncbi.nlm.ni...
PMID 16199891 View Gene Set 0.004039 18 0.04997 190 Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid. www.ncbi.nlm.ni...
PMID 16272310 View Gene Set 0.003918 10 0.04997 190 Functional analysis of HIV type 1 Nef reveals a role for PAK2 as a regulator of cell phenotype and function in the murine dendritic cell line DC2.4. www.ncbi.nlm.ni...
PMID 18668235 View Gene Set 0.004182 16 0.04997 190 Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese Malay and Indian in Singapore. www.ncbi.nlm.ni...
PMID 19000141 View Gene Set 0.004182 16 0.04997 190 Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java Kalimantan Timor and Irian Jaya. www.ncbi.nlm.ni...
PMID 19028820 View Gene Set 0.003942 33 0.04997 190 Polymorphisms in inflammatory genes and the risk of ischemic stroke and transient ischemic attack: results of a multilocus genotyping assay. www.ncbi.nlm.ni...
PMID 19167759 View Gene Set 0.004186 10 0.04997 190 HLA-association of serum levels of natural antibodies. www.ncbi.nlm.ni...
PMID 19218127 View Gene Set 0.004182 17 0.04997 190 [Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese]. www.ncbi.nlm.ni...
PMID 19264973 View Gene Set 0.004009 38 0.04997 190 Assessing the reproducibility of asthma candidate gene associations using genome-wide data. www.ncbi.nlm.ni...
PMID 19279038 View Gene Set 0.004182 16 0.04997 190 Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages. www.ncbi.nlm.ni...

Gene Set Collection: Prosite

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null PS50835 View Gene Set 1.998e-26 658 1.469e-23 1 IG_LIKE expasy.org/pros...
Null PS50026 View Gene Set 2.246e-15 207 5.889e-13 2 EGF_3 expasy.org/pros...
Null PS50262 View Gene Set 2.404e-15 765 5.889e-13 2 G_PROTEIN_RECEP_F1_2 expasy.org/pros...
Null PS00027 View Gene Set 1.726e-14 197 3.171e-12 4 HOMEOBOX_1 expasy.org/pros...
Null PS00022 View Gene Set 1.744e-13 151 2.563e-11 5 EGF_1 expasy.org/pros...
Null PS50071 View Gene Set 2.327e-13 264 2.85e-11 6 HOMEOBOX_2 expasy.org/pros...
Null PS00237 View Gene Set 2.897e-13 555 3.042e-11 7 G_PROTEIN_RECEP_F1_1 expasy.org/pros...
Null PS01186 View Gene Set 4.358e-13 171 4.004e-11 8 EGF_2 expasy.org/pros...
Null PS50853 View Gene Set 2.525e-10 181 2.062e-08 9 FN3 expasy.org/pros...
Null PS00290 View Gene Set 1.266e-09 86 9.304e-08 10 IG_MHC expasy.org/pros...
Null PS50092 View Gene Set 4.384e-09 68 2.929e-07 11 TSP1 expasy.org/pros...
Null PS01208 View Gene Set 4.894e-09 34 2.957e-07 12 VWFC_1 expasy.org/pros...
Null PS50184 View Gene Set 5.23e-09 35 2.957e-07 12 VWFC_2 expasy.org/pros...
Null PS00010 View Gene Set 1.052e-08 103 5.525e-07 14 ASX_HYDROXYL expasy.org/pros...
Null PS01187 View Gene Set 1.864e-08 99 9.133e-07 15 EGF_CA expasy.org/pros...
Null PS00203 View Gene Set 4.019e-08 13 1.846e-06 16 METALLOTHIONEIN_VRT expasy.org/pros...
Null PS50240 View Gene Set 2.655e-07 122 1.148e-05 17 TRYPSIN_DOM expasy.org/pros...
Null PS00375 View Gene Set 5.826e-07 23 2.254e-05 18 UDPGT expasy.org/pros...
Null PS51233 View Gene Set 5.775e-07 24 2.254e-05 18 VWFD expasy.org/pros...
Null PS00135 View Gene Set 1.096e-06 99 4.027e-05 20 TRYPSIN_SER expasy.org/pros...
Null PS50010 View Gene Set 1.219e-06 71 4.268e-05 21 DH_2 expasy.org/pros...
Null PS00134 View Gene Set 1.804e-06 104 6.026e-05 22 TRYPSIN_HIS expasy.org/pros...
Null PS50003 View Gene Set 5.68e-06 259 0.0001815 23 PH_DOMAIN expasy.org/pros...
Null PS50025 View Gene Set 6.071e-06 41 0.0001859 24 LAM_G_DOMAIN expasy.org/pros...
Null PS01225 View Gene Set 2.082e-05 24 0.0006121 25 CTCK_2 expasy.org/pros...
Null PS50923 View Gene Set 2.214e-05 57 0.000626 26 SUSHI expasy.org/pros...
Null PS50234 View Gene Set 3.098e-05 70 0.0008433 27 VWFA expasy.org/pros...
Null PS50002 View Gene Set 5.412e-05 212 0.001421 28 SH3 expasy.org/pros...
Null PS00086 View Gene Set 6.307e-05 55 0.001599 29 CYTOCHROME_P450 expasy.org/pros...
Null PS50041 View Gene Set 7.504e-05 88 0.001838 30 C_TYPE_LECTIN_2 expasy.org/pros...
Null PS51362 View Gene Set 8.837e-05 39 0.002095 31 TGF_BETA_2 expasy.org/pros...
Null PS00109 View Gene Set 0.0001116 98 0.002563 32 PROTEIN_KINASE_TYR expasy.org/pros...
Null PS00408 View Gene Set 0.0001618 20 0.003603 33 CONNEXINS_2 expasy.org/pros...
Null PS00407 View Gene Set 0.0001824 19 0.003942 34 CONNEXINS_1 expasy.org/pros...
Null PS01185 View Gene Set 0.000215 15 0.004515 35 CTCK_1 expasy.org/pros...
Null PS50837 View Gene Set 0.0002687 23 0.005486 36 NACHT expasy.org/pros...
Null PS50001 View Gene Set 0.0003109 110 0.006176 37 SH2 expasy.org/pros...
Null PS50189 View Gene Set 0.0003448 26 0.006668 38 NTR expasy.org/pros...
Null PS00284 View Gene Set 0.0003659 33 0.006724 39 SERPIN expasy.org/pros...
Null PS50106 View Gene Set 0.0003644 153 0.006724 39 PDZ expasy.org/pros...
Null PS00615 View Gene Set 0.0003774 45 0.006765 41 C_TYPE_LECTIN_1 expasy.org/pros...
Null PS00226 View Gene Set 0.0004632 69 0.008105 42 IF expasy.org/pros...
Null PS50088 View Gene Set 0.000506 273 0.008648 43 ANK_REPEAT expasy.org/pros...
Null PS50004 View Gene Set 0.0005403 115 0.009026 44 C2 expasy.org/pros...
Null PS00478 View Gene Set 0.0005691 71 0.009295 45 LIM_DOMAIN_1 expasy.org/pros...
Null PS50297 View Gene Set 0.0006047 285 0.009662 46 ANK_REP_REGION expasy.org/pros...
Null PS50824 View Gene Set 0.0007088 23 0.01108 47 DAPIN expasy.org/pros...
Null PS50009 View Gene Set 0.0007965 32 0.0122 48 RASGEF_CAT expasy.org/pros...
Null PS51004 View Gene Set 0.0008907 31 0.01336 49 SEMA expasy.org/pros...
Null PS50023 View Gene Set 0.0009917 73 0.01458 50 LIM_DOMAIN_2 expasy.org/pros...
Null PS50222 View Gene Set 0.001078 231 0.01554 51 EF_HAND_2 expasy.org/pros...
Null PS00250 View Gene Set 0.001102 33 0.01558 52 TGF_BETA_1 expasy.org/pros...
Null PS50888 View Gene Set 0.00137 114 0.019 53 HLH expasy.org/pros...
Null PS01031 View Gene Set 0.001495 10 0.02035 54 HSP20 expasy.org/pros...
Null PS50215 View Gene Set 0.001565 44 0.02054 55 ADAM_MEPRO expasy.org/pros...
Null PS51323 View Gene Set 0.001555 20 0.02054 55 IGFBP_N_2 expasy.org/pros...
Null PS00247 View Gene Set 0.001695 22 0.02149 57 HBGF_FGF expasy.org/pros...
Null PS51406 View Gene Set 0.001681 36 0.02149 57 FIBRINOGEN_C_2 expasy.org/pros...
Null PS00236 View Gene Set 0.002294 45 0.02858 59 NEUROTR_ION_CHANNEL expasy.org/pros...
Null PS00018 View Gene Set 0.002711 183 0.03253 60 EF_HAND_1 expasy.org/pros...
Null PS50871 View Gene Set 0.002744 32 0.03253 60 C1Q expasy.org/pros...
Null PS51055 View Gene Set 0.002673 8 0.03253 60 ITAM_1 expasy.org/pros...
Null PS51064 View Gene Set 0.002857 13 0.03333 63 IRS_PTB expasy.org/pros...
Null PS50027 View Gene Set 0.003036 29 0.03457 64 EGF_LAM_2 expasy.org/pros...
Null PS51021 View Gene Set 0.003057 15 0.03457 64 BAR expasy.org/pros...
Null PS50900 View Gene Set 0.003391 22 0.03777 66 PLAC expasy.org/pros...
Null PS00032 View Gene Set 0.003856 20 0.0423 67 ANTENNAPEDIA expasy.org/pros...
Null PS50024 View Gene Set 0.004276 19 0.04622 68 SEA expasy.org/pros...
Null PS50042 View Gene Set 0.004535 38 0.04831 69 CNMP_BINDING_3 expasy.org/pros...

Gene Set Collection: Enzyme

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null EC:2.4.1.17 View Gene Set 4.636e-06 19 0.0007324 1 Glucuronosyltransferase expasy.org/enzy...

Gene Set Collection: pathwayCommons.reactome

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Signaling by GPCR View Gene Set 2.17e-19 802 2.424e-16 1 REACTOME - Signaling by GPCR gene set www.pathwaycomm...
Null GPCR ligand binding View Gene Set 1.863e-13 339 1.04e-10 2 REACTOME - GPCR ligand binding gene set www.pathwaycomm...
Null GPCR downstream signaling View Gene Set 4.298e-11 595 1.6e-08 3 REACTOME - GPCR downstream signaling gene set www.pathwaycomm...
Null Class A/1 (Rhodopsin-like receptors) View Gene Set 8.272e-10 277 2.31e-07 4 REACTOME - Class A/1 (Rhodopsin-like receptors) gene set www.pathwaycomm...
Null Olfactory Signaling Pathway View Gene Set 2.141e-07 370 4.784e-05 5 REACTOME - Olfactory Signaling Pathway gene set www.pathwaycomm...
Null Peptide ligand-binding receptors View Gene Set 7.154e-07 167 0.0001332 6 REACTOME - Peptide ligand-binding receptors gene set www.pathwaycomm...
Null SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion View Gene Set 6.009e-05 19 0.009588 7 REACTOME - SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion gene set www.pathwaycomm...
Null Cytochrome P450 - arranged by substrate type View Gene Set 0.0001463 47 0.02042 8 REACTOME - Cytochrome P450 - arranged by substrate type gene set www.pathwaycomm...
Null Interaction between L1 and Ankyrins View Gene Set 0.0001775 14 0.02204 9 REACTOME - Interaction between L1 and Ankyrins gene set www.pathwaycomm...
Null Class B/2 (Secretin family receptors) View Gene Set 0.0002146 47 0.02397 10 REACTOME - Class B/2 (Secretin family receptors) gene set www.pathwaycomm...
Null Glucagon-type ligand receptors View Gene Set 0.000313 16 0.03179 11 REACTOME - Glucagon-type ligand receptors gene set www.pathwaycomm...
Null G alpha (s) signalling events View Gene Set 0.0003998 75 0.03721 12 REACTOME - G alpha (s) signalling events gene set www.pathwaycomm...
Null Thyroxine biosynthesis View Gene Set 0.000488 4 0.04193 13 REACTOME - Thyroxine biosynthesis gene set www.pathwaycomm...

Gene Set Collection: miranda.targets

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-661 View Gene Set 1.988e-06 2076 0.001346 1 microRNA targets for hsa-miR-661 from miranda.targets www.mirbase.org...
Null hsa-miR-744 View Gene Set 1.889e-05 797 0.006393 2 microRNA targets for hsa-miR-744 from miranda.targets www.mirbase.org...
Null hsa-miR-637 View Gene Set 3.187e-05 2291 0.007192 3 microRNA targets for hsa-miR-637 from miranda.targets www.mirbase.org...
Null hsa-miR-663 View Gene Set 4.43e-05 993 0.007499 4 microRNA targets for hsa-miR-663 from miranda.targets www.mirbase.org...
Null hsa-miR-886-3p View Gene Set 0.0001686 377 0.02283 5 microRNA targets for hsa-miR-886-3p from miranda.targets www.mirbase.org...
Null hsa-miR-296-5p View Gene Set 0.0002503 887 0.02824 6 microRNA targets for hsa-miR-296-5p from miranda.targets www.mirbase.org...
Null hsa-miR-342-5p View Gene Set 0.0003262 861 0.03155 7 microRNA targets for hsa-miR-342-5p from miranda.targets www.mirbase.org...
Null hsa-miR-615-5p View Gene Set 0.0005093 1189 0.0431 8 microRNA targets for hsa-miR-615-5p from miranda.targets www.mirbase.org...

Gene Set Collection: mirbase.targets

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-663 View Gene Set 2.519e-17 743 1.791e-14 1 microRNA targets for hsa-miR-663 from mirbase.targets www.mirbase.org...
Null hsa-miR-615-5p View Gene Set 1.703e-12 848 6.055e-10 2 microRNA targets for hsa-miR-615-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-886-3p View Gene Set 7.225e-12 745 1.712e-09 3 microRNA targets for hsa-miR-886-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-326 View Gene Set 2.352e-11 650 4.18e-09 4 microRNA targets for hsa-miR-326 from mirbase.targets www.mirbase.org...
Null hsa-miR-330-5p View Gene Set 3.517e-11 728 5.001e-09 5 microRNA targets for hsa-miR-330-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-886-5p View Gene Set 1.36e-10 793 1.611e-08 6 microRNA targets for hsa-miR-886-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-296-5p View Gene Set 2.184e-09 755 2.218e-07 7 microRNA targets for hsa-miR-296-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-423-3p View Gene Set 1.684e-08 741 1.497e-06 8 microRNA targets for hsa-miR-423-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-760 View Gene Set 3.012e-08 690 2.379e-06 9 microRNA targets for hsa-miR-760 from mirbase.targets www.mirbase.org...
Null hsa-miR-560 View Gene Set 4.821e-08 730 3.427e-06 10 microRNA targets for hsa-miR-560 from mirbase.targets www.mirbase.org...
Null hsa-miR-149* View Gene Set 8.13e-08 459 5.255e-06 11 microRNA targets for hsa-miR-149* from mirbase.targets www.mirbase.org...
Null hsa-miR-637 View Gene Set 3.08e-07 672 1.825e-05 12 microRNA targets for hsa-miR-637 from mirbase.targets www.mirbase.org...
Null hsa-miR-92b* View Gene Set 3.383e-07 648 1.85e-05 13 microRNA targets for hsa-miR-92b* from mirbase.targets www.mirbase.org...
Null hsa-miR-328 View Gene Set 3.992e-07 685 2.028e-05 14 microRNA targets for hsa-miR-328 from mirbase.targets www.mirbase.org...
Null hsa-miR-593 View Gene Set 7.12e-07 556 3.375e-05 15 microRNA targets for hsa-miR-593 from mirbase.targets www.mirbase.org...
Null hsa-miR-939 View Gene Set 8.905e-07 667 3.957e-05 16 microRNA targets for hsa-miR-939 from mirbase.targets www.mirbase.org...
Null hsa-miR-92a-2* View Gene Set 1.293e-06 654 5.406e-05 17 microRNA targets for hsa-miR-92a-2* from mirbase.targets www.mirbase.org...
Null hsa-miR-486-3p View Gene Set 1.824e-06 773 7.206e-05 18 microRNA targets for hsa-miR-486-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-885-3p View Gene Set 2.214e-06 799 8.284e-05 19 microRNA targets for hsa-miR-885-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-370 View Gene Set 2.336e-06 710 8.304e-05 20 microRNA targets for hsa-miR-370 from mirbase.targets www.mirbase.org...
Null hsa-miR-571 View Gene Set 3.015e-06 720 0.0001021 21 microRNA targets for hsa-miR-571 from mirbase.targets www.mirbase.org...
Null hsa-miR-185* View Gene Set 3.419e-06 506 0.0001057 22 microRNA targets for hsa-miR-185* from mirbase.targets www.mirbase.org...
Null hsa-miR-615-3p View Gene Set 3.329e-06 757 0.0001057 22 microRNA targets for hsa-miR-615-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-484 View Gene Set 5.001e-06 733 0.0001482 24 microRNA targets for hsa-miR-484 from mirbase.targets www.mirbase.org...
Null hsa-miR-608 View Gene Set 6.732e-06 729 0.0001915 25 microRNA targets for hsa-miR-608 from mirbase.targets www.mirbase.org...
Null hsa-miR-609 View Gene Set 9.359e-06 687 0.0002559 26 microRNA targets for hsa-miR-609 from mirbase.targets www.mirbase.org...
Null hsa-miR-937 View Gene Set 1.238e-05 654 0.0003261 27 microRNA targets for hsa-miR-937 from mirbase.targets www.mirbase.org...
Null hsa-miR-658 View Gene Set 1.341e-05 660 0.0003406 28 microRNA targets for hsa-miR-658 from mirbase.targets www.mirbase.org...
Null hsa-miR-638 View Gene Set 1.394e-05 639 0.0003418 29 microRNA targets for hsa-miR-638 from mirbase.targets www.mirbase.org...
Null hsa-miR-675 View Gene Set 1.861e-05 686 0.0004411 30 microRNA targets for hsa-miR-675 from mirbase.targets www.mirbase.org...
Null hsa-miR-139-3p View Gene Set 2.454e-05 736 0.0005286 31 microRNA targets for hsa-miR-139-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-565 View Gene Set 2.447e-05 689 0.0005286 31 microRNA targets for hsa-miR-565 from mirbase.targets www.mirbase.org...
Null hsa-miR-744 View Gene Set 2.375e-05 715 0.0005286 31 microRNA targets for hsa-miR-744 from mirbase.targets www.mirbase.org...
Null hsa-miR-339-3p View Gene Set 2.718e-05 797 0.0005684 34 microRNA targets for hsa-miR-339-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-611 View Gene Set 3.422e-05 671 0.0006951 35 microRNA targets for hsa-miR-611 from mirbase.targets www.mirbase.org...
Null hsa-miR-23a* View Gene Set 3.655e-05 604 0.0007218 36 microRNA targets for hsa-miR-23a* from mirbase.targets www.mirbase.org...
Null hsa-miR-654-5p View Gene Set 3.979e-05 718 0.0007647 37 microRNA targets for hsa-miR-654-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-491-5p View Gene Set 4.255e-05 731 0.0007961 38 microRNA targets for hsa-miR-491-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-661 View Gene Set 5.113e-05 575 0.0009321 39 microRNA targets for hsa-miR-661 from mirbase.targets www.mirbase.org...
Null hsa-miR-342-5p View Gene Set 5.312e-05 698 0.0009443 40 microRNA targets for hsa-miR-342-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-214* View Gene Set 6.004e-05 434 0.001041 41 microRNA targets for hsa-miR-214* from mirbase.targets www.mirbase.org...
Null hsa-miR-765 View Gene Set 6.149e-05 674 0.001041 41 microRNA targets for hsa-miR-765 from mirbase.targets www.mirbase.org...
Null hsa-miR-877* View Gene Set 6.524e-05 479 0.001079 43 microRNA targets for hsa-miR-877* from mirbase.targets www.mirbase.org...
Null hsa-miR-631 View Gene Set 6.915e-05 714 0.001117 44 microRNA targets for hsa-miR-631 from mirbase.targets www.mirbase.org...
Null hsa-miR-125b-1* View Gene Set 8.42e-05 622 0.001301 45 microRNA targets for hsa-miR-125b-1* from mirbase.targets www.mirbase.org...
Null hsa-miR-596 View Gene Set 8.313e-05 644 0.001301 45 microRNA targets for hsa-miR-596 from mirbase.targets www.mirbase.org...
Null hsa-miR-323-5p View Gene Set 0.000144 763 0.002145 47 microRNA targets for hsa-miR-323-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-339-5p View Gene Set 0.0001478 659 0.002145 47 microRNA targets for hsa-miR-339-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-602 View Gene Set 0.000145 710 0.002145 47 microRNA targets for hsa-miR-602 from mirbase.targets www.mirbase.org...
Null hsa-miR-874 View Gene Set 0.0001868 722 0.002657 50 microRNA targets for hsa-miR-874 from mirbase.targets www.mirbase.org...
Null hsa-miR-541 View Gene Set 0.0002373 711 0.003308 51 microRNA targets for hsa-miR-541 from mirbase.targets www.mirbase.org...
Null hsa-miR-296-3p View Gene Set 0.0002747 905 0.003685 52 microRNA targets for hsa-miR-296-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-769-5p View Gene Set 0.0002725 790 0.003685 52 microRNA targets for hsa-miR-769-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-665 View Gene Set 0.0002883 617 0.003796 54 microRNA targets for hsa-miR-665 from mirbase.targets www.mirbase.org...
Null hsa-miR-500* View Gene Set 0.0003233 538 0.004179 55 microRNA targets for hsa-miR-500* from mirbase.targets www.mirbase.org...
Null hsa-miR-612 View Gene Set 0.0003507 685 0.004452 56 microRNA targets for hsa-miR-612 from mirbase.targets www.mirbase.org...
Null hsa-miR-453 View Gene Set 0.0003735 702 0.004659 57 microRNA targets for hsa-miR-453 from mirbase.targets www.mirbase.org...
Null hsa-miR-204 View Gene Set 0.0003818 640 0.00468 58 microRNA targets for hsa-miR-204 from mirbase.targets www.mirbase.org...
Null hsa-miR-324-3p View Gene Set 0.0003898 788 0.004697 59 microRNA targets for hsa-miR-324-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-191* View Gene Set 0.0004009 462 0.004751 60 microRNA targets for hsa-miR-191* from mirbase.targets www.mirbase.org...
Null hsa-miR-23b* View Gene Set 0.0004416 544 0.005147 61 microRNA targets for hsa-miR-23b* from mirbase.targets www.mirbase.org...
Null hsa-miR-639 View Gene Set 0.0004863 561 0.00555 62 microRNA targets for hsa-miR-639 from mirbase.targets www.mirbase.org...
Null hsa-miR-668 View Gene Set 0.0004918 560 0.00555 62 microRNA targets for hsa-miR-668 from mirbase.targets www.mirbase.org...
Null hsa-miR-193a-5p View Gene Set 0.000501 767 0.005566 64 microRNA targets for hsa-miR-193a-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-483-3p View Gene Set 0.0005221 702 0.005711 65 microRNA targets for hsa-miR-483-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-125b View Gene Set 0.0005466 831 0.005888 66 microRNA targets for hsa-miR-125b from mirbase.targets www.mirbase.org...
Null hsa-miR-331-3p View Gene Set 0.000604 712 0.00641 67 microRNA targets for hsa-miR-331-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-647 View Gene Set 0.0006765 724 0.007074 68 microRNA targets for hsa-miR-647 from mirbase.targets www.mirbase.org...
Null hsa-miR-340* View Gene Set 0.0007872 358 0.008112 69 microRNA targets for hsa-miR-340* from mirbase.targets www.mirbase.org...
Null hsa-miR-942 View Gene Set 0.001047 583 0.01063 70 microRNA targets for hsa-miR-942 from mirbase.targets www.mirbase.org...
Null hsa-miR-25* View Gene Set 0.00113 418 0.01132 71 microRNA targets for hsa-miR-25* from mirbase.targets www.mirbase.org...
Null hsa-miR-151-5p View Gene Set 0.001173 749 0.01158 72 microRNA targets for hsa-miR-151-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-324-5p View Gene Set 0.001359 801 0.01324 73 microRNA targets for hsa-miR-324-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-512-5p View Gene Set 0.00146 693 0.01384 74 microRNA targets for hsa-miR-512-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-604 View Gene Set 0.001456 691 0.01384 74 microRNA targets for hsa-miR-604 from mirbase.targets www.mirbase.org...
Null hsa-miR-542-5p View Gene Set 0.001488 774 0.01392 76 microRNA targets for hsa-miR-542-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-941 View Gene Set 0.001523 590 0.01406 77 microRNA targets for hsa-miR-941 from mirbase.targets www.mirbase.org...
Null hsa-miR-769-3p View Gene Set 0.001786 823 0.01628 78 microRNA targets for hsa-miR-769-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-125a-5p View Gene Set 0.002159 817 0.01919 79 microRNA targets for hsa-miR-125a-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-127-3p View Gene Set 0.002134 653 0.01919 79 microRNA targets for hsa-miR-127-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-629* View Gene Set 0.002266 382 0.01989 81 microRNA targets for hsa-miR-629* from mirbase.targets www.mirbase.org...
Null hsa-miR-920 View Gene Set 0.002405 661 0.0206 82 microRNA targets for hsa-miR-920 from mirbase.targets www.mirbase.org...
Null hsa-miR-92a-1* View Gene Set 0.002384 661 0.0206 82 microRNA targets for hsa-miR-92a-1* from mirbase.targets www.mirbase.org...
Null hsa-miR-431* View Gene Set 0.002511 547 0.02126 84 microRNA targets for hsa-miR-431* from mirbase.targets www.mirbase.org...
Null hsa-miR-361-3p View Gene Set 0.002865 634 0.02396 85 microRNA targets for hsa-miR-361-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-422a View Gene Set 0.002922 755 0.02416 86 microRNA targets for hsa-miR-422a from mirbase.targets www.mirbase.org...
Null hsa-miR-505* View Gene Set 0.003039 516 0.02484 87 microRNA targets for hsa-miR-505* from mirbase.targets www.mirbase.org...
Null hsa-miR-214 View Gene Set 0.003425 797 0.02736 88 microRNA targets for hsa-miR-214 from mirbase.targets www.mirbase.org...
Null hsa-miR-371-3p View Gene Set 0.0034 750 0.02736 88 microRNA targets for hsa-miR-371-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-27a* View Gene Set 0.003563 616 0.02815 90 microRNA targets for hsa-miR-27a* from mirbase.targets www.mirbase.org...
Null hsa-miR-614 View Gene Set 0.004572 578 0.03533 91 microRNA targets for hsa-miR-614 from mirbase.targets www.mirbase.org...
Null hsa-miR-662 View Gene Set 0.004554 663 0.03533 91 microRNA targets for hsa-miR-662 from mirbase.targets www.mirbase.org...
Null hsa-miR-423-5p View Gene Set 0.004673 767 0.03572 93 microRNA targets for hsa-miR-423-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-205 View Gene Set 0.004733 687 0.0358 94 microRNA targets for hsa-miR-205 from mirbase.targets www.mirbase.org...
Null hsa-miR-432* View Gene Set 0.005448 544 0.04077 95 microRNA targets for hsa-miR-432* from mirbase.targets www.mirbase.org...
Null hsa-miR-572 View Gene Set 0.005818 602 0.04309 96 microRNA targets for hsa-miR-572 from mirbase.targets www.mirbase.org...
Null hsa-miR-299-3p View Gene Set 0.006067 732 0.04447 97 microRNA targets for hsa-miR-299-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-650 View Gene Set 0.00615 693 0.04462 98 microRNA targets for hsa-miR-650 from mirbase.targets www.mirbase.org...
Null hsa-miR-940 View Gene Set 0.00658 660 0.04726 99 microRNA targets for hsa-miR-940 from mirbase.targets www.mirbase.org...

Gene Set Collection: miRNAtargetUnion

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-663 View Gene Set 8.642e-15 1582 2e-11 1 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-663 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-886-3p View Gene Set 3.041e-14 1039 3.518e-11 2 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-886-3p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-615-5p View Gene Set 2.445e-12 1865 1.886e-09 3 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-615-5p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-296-5p View Gene Set 6.482e-11 1519 3.75e-08 4 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-296-5p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-661 View Gene Set 5.091e-10 2615 2.356e-07 5 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-661 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.targetscan.targetsUnion.hsa-miR-326 View Gene Set 7.514e-09 2156 2.898e-06 6 microRNA targets for miranda.mirbase.targetscan.targetsUnion.hsa-miR-326 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-326 View Gene Set 2.527e-08 2147 8.355e-06 7 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-326 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-886-5p View Gene Set 2.938e-08 1187 8.499e-06 8 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-886-5p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-637 View Gene Set 7.029e-08 2846 1.807e-05 9 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-637 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.pictar.targetsUnion.hsa-miR-326 View Gene Set 9.789e-08 2171 2.265e-05 10 microRNA targets for miranda.mirbase.pictar.targetsUnion.hsa-miR-326 from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-326 View Gene Set 1.126e-07 1065 2.368e-05 11 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-326 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-423-3p View Gene Set 1.504e-07 1053 2.899e-05 12 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-423-3p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-615-3p View Gene Set 1.873e-07 1113 3.096e-05 13 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-615-3p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.targetscan.targetsUnion.hsa-miR-615-3p View Gene Set 1.857e-07 1112 3.096e-05 13 microRNA targets for miranda.mirbase.targetscan.targetsUnion.hsa-miR-615-3p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-744 View Gene Set 2.093e-07 1378 3.228e-05 15 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-744 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-342-5p View Gene Set 2.257e-07 1470 3.265e-05 16 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-342-5p from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-330-5p View Gene Set 3.351e-07 1142 4.561e-05 17 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-330-5p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-654-5p View Gene Set 1.087e-06 1681 0.0001398 18 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-654-5p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-638 View Gene Set 1.353e-06 1054 0.0001566 19 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-638 from miRNAtargetUnion www.mirbase.org...
Null mirbase.pictar.targetscan.targetsUnion.hsa-miR-326 View Gene Set 1.294e-06 1071 0.0001566 19 microRNA targets for mirbase.pictar.targetscan.targetsUnion.hsa-miR-326 from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.pictar.targetsUnion.hsa-miR-326 View Gene Set 3.063e-06 1066 0.0003376 21 microRNA targets for mirbase.mirtarget2.pictar.targetsUnion.hsa-miR-326 from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-615-3p View Gene Set 3.295e-06 764 0.0003466 22 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-615-3p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-339-3p View Gene Set 4.591e-06 1044 0.0004619 23 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-339-3p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-331-3p View Gene Set 6.25e-06 1764 0.0006026 24 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-331-3p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.targetscan.targetsUnion.hsa-miR-330-5p View Gene Set 9.482e-06 2574 0.0008777 25 microRNA targets for miranda.mirbase.targetscan.targetsUnion.hsa-miR-330-5p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-675 View Gene Set 1.314e-05 1108 0.001169 26 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-675 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-484 View Gene Set 1.711e-05 1853 0.001414 27 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-484 from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.pictar.targetsUnion.hsa-miR-328 View Gene Set 1.656e-05 946 0.001414 27 microRNA targets for mirbase.mirtarget2.pictar.targetsUnion.hsa-miR-328 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.targetscan.targetsUnion.hsa-miR-874 View Gene Set 2.181e-05 1806 0.001741 29 microRNA targets for miranda.mirbase.targetscan.targetsUnion.hsa-miR-874 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-571 View Gene Set 3.179e-05 1591 0.002401 30 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-571 from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-328 View Gene Set 3.217e-05 872 0.002401 30 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-328 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-596 View Gene Set 3.483e-05 1484 0.002519 32 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-596 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-330-5p View Gene Set 3.948e-05 2597 0.002768 33 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-330-5p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-593 View Gene Set 4.259e-05 1838 0.002816 34 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-593 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-874 View Gene Set 4.24e-05 1840 0.002816 34 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-874 from miRNAtargetUnion www.mirbase.org...
Null mirbase.pictar.targetscan.targetsUnion.hsa-miR-328 View Gene Set 5.114e-05 916 0.003287 36 microRNA targets for mirbase.pictar.targetscan.targetsUnion.hsa-miR-328 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-541 View Gene Set 5.258e-05 1832 0.003288 37 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-541 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-611 View Gene Set 6.507e-05 1017 0.003962 38 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-611 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-937 View Gene Set 7.814e-05 820 0.004637 39 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-937 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-631 View Gene Set 8.106e-05 1374 0.004689 40 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-631 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-658 View Gene Set 0.0001031 1603 0.005817 41 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-658 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-328 View Gene Set 0.000117 1858 0.006449 42 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-328 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-608 View Gene Set 0.0001337 3384 0.006938 43 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-608 from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-296-3p View Gene Set 0.0001337 1042 0.006938 43 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-296-3p from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-874 View Gene Set 0.0001349 975 0.006938 43 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-874 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.targetscan.targetsUnion.hsa-miR-328 View Gene Set 0.0001859 1838 0.009351 46 microRNA targets for miranda.mirbase.targetscan.targetsUnion.hsa-miR-328 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-939 View Gene Set 0.0003157 2729 0.01554 47 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-939 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.pictar.targetsUnion.hsa-miR-328 View Gene Set 0.0003404 1892 0.01641 48 microRNA targets for miranda.mirbase.pictar.targetsUnion.hsa-miR-328 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-423-5p View Gene Set 0.0004395 2496 0.02075 49 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-423-5p from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-370 View Gene Set 0.0005471 1067 0.02532 50 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-370 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-370 View Gene Set 0.0005848 2143 0.02653 51 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-370 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-760 View Gene Set 0.0005963 2252 0.02653 51 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-760 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-602 View Gene Set 0.0006186 1257 0.02691 53 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-602 from miRNAtargetUnion www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-491-5p View Gene Set 0.000628 954 0.02691 53 microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-491-5p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-324-3p View Gene Set 0.0008341 1946 0.03509 55 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-324-3p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.tarbase.targetsUnion.hsa-miR-24 View Gene Set 0.0008649 2089 0.03574 56 microRNA targets for miranda.mirbase.tarbase.targetsUnion.hsa-miR-24 from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.targetscan.targetsUnion.hsa-miR-24 View Gene Set 0.001065 2258 0.04323 57 microRNA targets for miranda.mirbase.targetscan.targetsUnion.hsa-miR-24 from miRNAtargetUnion www.mirbase.org...

Gene Set Collection: hprdBatch.UP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL-3 Signaling Pathway View Gene Set 0.0009843 40 0.01574 1 From NetPath for IL-3 Signaling Pathway www.netpath.org...
Null IL-6 Signaling Pathway View Gene Set 0.001574 80 0.01574 1 From NetPath for IL-6 Signaling Pathway www.netpath.org...
Null IL-4 Signaling Pathway View Gene Set 0.007046 217 0.04697 3 From NetPath for IL-4 Signaling Pathway www.netpath.org...

Gene Set Collection: hprdBatch.DOWN

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL-4 Signaling Pathway View Gene Set 0.001697 90 0.03224 1 From NetPath for IL-4 Signaling Pathway www.netpath.org...

Gene Set Collection: hprdBatch.DIFFERENT

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL-4 Signaling Pathway View Gene Set 0.0002419 301 0.004837 1 From NetPath for IL-4 Signaling Pathway www.netpath.org...
Null IL-3 Signaling Pathway View Gene Set 0.004172 49 0.04172 2 From NetPath for IL-3 Signaling Pathway www.netpath.org...

Gene Set Collection: hprdManual.UP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL1 View Gene Set 0.0001393 85 0.003344 1 From NetPath for IL1 www.netpath.org...
Null TNFalpha View Gene Set 0.001153 113 0.01383 2 From NetPath for TNFalpha www.netpath.org...
Null IL3 View Gene Set 0.006122 17 0.03602 3 From NetPath for IL3 www.netpath.org...
Null Leptin View Gene Set 0.005125 31 0.03602 3 From NetPath for Leptin www.netpath.org...
Null TSH View Gene Set 0.007505 48 0.03602 3 From NetPath for TSH www.netpath.org...

Gene Set Collection: hprdManual.DOWN

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL4 View Gene Set 0.004827 77 0.04782 1 From NetPath for IL4 www.netpath.org...
Null Leptin View Gene Set 0.005033 79 0.04782 1 From NetPath for Leptin www.netpath.org...
Null IL1 View Gene Set 0.007823 35 0.04954 3 From NetPath for IL1 www.netpath.org...

Gene Set Collection: hprdManual.DIFFERENT

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL1 View Gene Set 6.215e-06 120 0.0001492 1 From NetPath for IL1 www.netpath.org...
Null Leptin View Gene Set 0.0001871 110 0.002245 2 From NetPath for Leptin www.netpath.org...
Null TNFalpha View Gene Set 0.0003251 121 0.002601 3 From NetPath for TNFalpha www.netpath.org...
Null IL4 View Gene Set 0.002297 269 0.01378 4 From NetPath for IL4 www.netpath.org...
Null IL3 View Gene Set 0.005257 20 0.02523 5 From NetPath for IL3 www.netpath.org...

Gene Set Collection: tfbsK3Z3

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null V_AP1_01 View Gene Set 7.094e-08 169 1.511e-05 1 List of genes containing a conserved (FDR < 0.1%) V$AP1_01 TFBS located within 3 kb around the TSS for the AP-1 transcription factor www.gene-regula...
Null V_RFX1_02 View Gene Set 4.936e-06 364 0.0005256 2 List of genes containing a conserved (FDR < 0.1%) V$RFX1_02 TFBS located within 3 kb around the TSS for the RFX1 transcription factor www.gene-regula...
Null V_MEIS1AHOXA9_01 View Gene Set 1.576e-05 263 0.0006712 3 List of genes containing a conserved (FDR < 0.1%) V$MEIS1AHOXA9_01 TFBS located within 3 kb around the TSS for the HOXA9B transcription factor www.gene-regula...
Null V_NRSF_01 View Gene Set 1.13e-05 256 0.0006712 3 List of genes containing a conserved (FDR < 0.1%) V$NRSF_01 TFBS located within 3 kb around the TSS for the NRSF form 1 transcription factor www.gene-regula...
Null V_OCT_C View Gene Set 1.318e-05 316 0.0006712 3 List of genes containing a conserved (FDR < 0.1%) V$OCT_C TFBS located within 3 kb around the TSS for the Oct-B1 transcription factor www.gene-regula...
Null V_CDPCR3HD_01 View Gene Set 6.385e-05 100 0.001943 6 List of genes containing a conserved (FDR < 0.1%) V$CDPCR3HD_01 TFBS located within 3 kb around the TSS for the CUTL1 transcription factor www.gene-regula...
Null V_ROAZ_01 View Gene Set 5.498e-05 189 0.001943 6 List of genes containing a conserved (FDR < 0.1%) V$ROAZ_01 TFBS located within 3 kb around the TSS for the Roaz transcription factor www.gene-regula...
Null V_LUN1_01 View Gene Set 0.0001172 194 0.00257 8 List of genes containing a conserved (FDR < 0.1%) V$LUN1_01 TFBS located within 3 kb around the TSS for the LUN-1 transcription factor www.gene-regula...
Null V_POU3F2_02 View Gene Set 0.0001206 261 0.00257 8 List of genes containing a conserved (FDR < 0.1%) V$POU3F2_02 TFBS located within 3 kb around the TSS for the POU3F2 transcription factor www.gene-regula...
Null V_PPARG_01 View Gene Set 0.0001177 386 0.00257 8 List of genes containing a conserved (FDR < 0.1%) V$PPARG_01 TFBS located within 3 kb around the TSS for the PPAR-gamma1 transcription factor www.gene-regula...
Null V_RSRFC4_01 View Gene Set 0.0001355 394 0.002625 11 List of genes containing a conserved (FDR < 0.1%) V$RSRFC4_01 TFBS located within 3 kb around the TSS for the RSRFC4 transcription factor www.gene-regula...
Null V_CART1_01 View Gene Set 0.000224 248 0.003181 12 List of genes containing a conserved (FDR < 0.1%) V$CART1_01 TFBS located within 3 kb around the TSS for the Cart-1 transcription factor www.gene-regula...
Null V_HOXA3_01 View Gene Set 0.0002026 81 0.003181 12 List of genes containing a conserved (FDR < 0.1%) V$HOXA3_01 TFBS located within 3 kb around the TSS for the HOXA3 transcription factor www.gene-regula...
Null V_LHX3_01 View Gene Set 0.0002154 80 0.003181 12 List of genes containing a conserved (FDR < 0.1%) V$LHX3_01 TFBS located within 3 kb around the TSS for the LHX3a transcription factor www.gene-regula...
Null V_NFE2_01 View Gene Set 0.0002088 213 0.003181 12 List of genes containing a conserved (FDR < 0.1%) V$NFE2_01 TFBS located within 3 kb around the TSS for the NF-E2 transcription factor www.gene-regula...
Null V_NKX25_02 View Gene Set 0.0002771 252 0.003689 16 List of genes containing a conserved (FDR < 0.1%) V$NKX25_02 TFBS located within 3 kb around the TSS for the Nkx2-5 transcription factor www.gene-regula...
Null V_HNF4_01 View Gene Set 0.0003333 11 0.004176 17 List of genes containing a conserved (FDR < 0.1%) V$HNF4_01 TFBS located within 3 kb around the TSS for the HNF-4alpha2 transcription factor www.gene-regula...
Null V_MEF2_01 View Gene Set 0.0003549 385 0.0042 18 List of genes containing a conserved (FDR < 0.1%) V$MEF2_01 TFBS located within 3 kb around the TSS for the MEF-2A transcription factor www.gene-regula...
Null V_PBX1_02 View Gene Set 0.0004815 223 0.005398 19 List of genes containing a conserved (FDR < 0.1%) V$PBX1_02 TFBS located within 3 kb around the TSS for the Pbx1a transcription factor www.gene-regula...
Null V_FAC1_01 View Gene Set 0.0005483 172 0.005839 20 List of genes containing a conserved (FDR < 0.1%) V$FAC1_01 TFBS located within 3 kb around the TSS for the FAC1 transcription factor www.gene-regula...
Null V_MEF2_02 View Gene Set 0.0007876 157 0.007626 21 List of genes containing a conserved (FDR < 0.1%) V$MEF2_02 TFBS located within 3 kb around the TSS for the MEF-2A transcription factor www.gene-regula...
Null V_NKX61_01 View Gene Set 0.0007872 186 0.007626 21 List of genes containing a conserved (FDR < 0.1%) V$NKX61_01 TFBS located within 3 kb around the TSS for the Nkx6-1 transcription factor www.gene-regula...
Null V_POU3F2_01 View Gene Set 0.0008908 324 0.008249 23 List of genes containing a conserved (FDR < 0.1%) V$POU3F2_01 TFBS located within 3 kb around the TSS for the POU3F2 transcription factor www.gene-regula...
Null V_LMO2COM_02 View Gene Set 0.001067 138 0.009095 24 List of genes containing a conserved (FDR < 0.1%) V$LMO2COM_02 TFBS located within 3 kb around the TSS for the Lmo2 transcription factor www.gene-regula...
Null V_POU6F1_01 View Gene Set 0.001036 200 0.009095 24 List of genes containing a conserved (FDR < 0.1%) V$POU6F1_01 TFBS located within 3 kb around the TSS for the POU6F1 (c2) transcription factor www.gene-regula...
Null V_EVI1_02 View Gene Set 0.00165 110 0.01352 26 List of genes containing a conserved (FDR < 0.1%) V$EVI1_02 TFBS located within 3 kb around the TSS for the Evi-1 transcription factor www.gene-regula...
Null V_IK1_01 View Gene Set 0.001899 106 0.01445 27 List of genes containing a conserved (FDR < 0.1%) V$IK1_01 TFBS located within 3 kb around the TSS for the Ik-1 transcription factor www.gene-regula...
Null V_PPARG_02 View Gene Set 0.001894 151 0.01445 27 List of genes containing a conserved (FDR < 0.1%) V$PPARG_02 TFBS located within 3 kb around the TSS for the PPAR-gamma1 transcription factor www.gene-regula...
Null V_NKX22_01 View Gene Set 0.00226 246 0.0166 29 List of genes containing a conserved (FDR < 0.1%) V$NKX22_01 TFBS located within 3 kb around the TSS for the Nkx2-2 transcription factor www.gene-regula...
Null V_ER_Q6 View Gene Set 0.002748 146 0.01951 30 List of genes containing a conserved (FDR < 0.1%) V$ER_Q6 TFBS located within 3 kb around the TSS for the ER-alpha transcription factor www.gene-regula...
Null V_SEF1_C View Gene Set 0.002899 141 0.01992 31 List of genes containing a conserved (FDR < 0.1%) V$SEF1_C TFBS located within 3 kb around the TSS for the SEF-1 (1) transcription factor www.gene-regula...
Null V_EVI1_01 View Gene Set 0.003462 265 0.02304 32 List of genes containing a conserved (FDR < 0.1%) V$EVI1_01 TFBS located within 3 kb around the TSS for the Evi-1 transcription factor www.gene-regula...
Null V_MEF2_03 View Gene Set 0.003828 164 0.02457 33 List of genes containing a conserved (FDR < 0.1%) V$MEF2_03 TFBS located within 3 kb around the TSS for the MEF-2A transcription factor www.gene-regula...
Null V_PAX4_02 View Gene Set 0.003922 121 0.02457 33 List of genes containing a conserved (FDR < 0.1%) V$PAX4_02 TFBS located within 3 kb around the TSS for the Pax-4a transcription factor www.gene-regula...
Null V_OCT1_01 View Gene Set 0.004231 70 0.02575 35 List of genes containing a conserved (FDR < 0.1%) V$OCT1_01 TFBS located within 3 kb around the TSS for the POU2F1 transcription factor www.gene-regula...
Null V_STAT5B_01 View Gene Set 0.004688 50 0.02774 36 List of genes containing a conserved (FDR < 0.1%) V$STAT5B_01 TFBS located within 3 kb around the TSS for the STAT5B transcription factor www.gene-regula...
Null V_HNF1_01 View Gene Set 0.004852 185 0.02793 37 List of genes containing a conserved (FDR < 0.1%) V$HNF1_01 TFBS located within 3 kb around the TSS for the HNF-1A transcription factor www.gene-regula...
Null V_HAND1E47_01 View Gene Set 0.005535 82 0.03103 38 List of genes containing a conserved (FDR < 0.1%) V$HAND1E47_01 TFBS located within 3 kb around the TSS for the E47 transcription factor www.gene-regula...
Null V_MEF2_04 View Gene Set 0.005695 227 0.0311 39 List of genes containing a conserved (FDR < 0.1%) V$MEF2_04 TFBS located within 3 kb around the TSS for the MEF-2A transcription factor www.gene-regula...
Null V_CDPCR1_01 View Gene Set 0.006116 160 0.03257 40 List of genes containing a conserved (FDR < 0.1%) V$CDPCR1_01 TFBS located within 3 kb around the TSS for the CUTL1 transcription factor www.gene-regula...
Null V_COUP_01 View Gene Set 0.007267 251 0.03775 41 List of genes containing a conserved (FDR < 0.1%) V$COUP_01 TFBS located within 3 kb around the TSS for the COUP-TF1 transcription factor www.gene-regula...
Null V_OCT1_04 View Gene Set 0.007511 82 0.03809 42 List of genes containing a conserved (FDR < 0.1%) V$OCT1_04 TFBS located within 3 kb around the TSS for the POU2F1 transcription factor www.gene-regula...
Null V_SRF_C View Gene Set 0.008882 120 0.044 43 List of genes containing a conserved (FDR < 0.1%) V$SRF_C TFBS located within 3 kb around the TSS for the SRF transcription factor www.gene-regula...