Results

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Go to: Gene Set Collection: KEGG
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Go to: Gene Set Collection: Broad.c2.CGP
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Go to: Gene Set Collection: Broad.c2.CP.KEGG
Go to: Gene Set Collection: Broad.c2.CP.REACTOME
Go to: Gene Set Collection: Broad.c3.TFT
Go to: Gene Set Collection: Broad.c4.CGN
Go to: Gene Set Collection: Broad.c4.CM
Go to: Gene Set Collection: Broad.c5.BP
Go to: Gene Set Collection: Broad.c5.CC
Go to: Gene Set Collection: Broad.c5.MF
Go to: Gene Set Collection: PMID
Go to: Gene Set Collection: Prosite
Go to: Gene Set Collection: pathwayCommons.reactome
Go to: Gene Set Collection: mirbase.targets
Go to: Gene Set Collection: miRNAtargetUnion
Go to: Gene Set Collection: hprdBatch.UP
Go to: Gene Set Collection: hprdBatch.DIFFERENT
Go to: Gene Set Collection: hprdManual.UP
Go to: Gene Set Collection: hprdManual.DOWN
Go to: Gene Set Collection: hprdManual.DIFFERENT
Go to: Gene Set Collection: tfbsK3Z3

AFA results for: TSAvsControl

Click on the heading for any column to sort by that column.

Gene Set Collection: KEGG

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
KEGG 04080 View Gene Set 1.961e-12 272 4.197e-10 1 Neuroactive ligand-receptor interaction www.genome.jp/d...
KEGG 04060 View Gene Set 6.463e-10 266 6.916e-08 2 Cytokine-cytokine receptor interaction www.genome.jp/d...
KEGG 04740 View Gene Set 9.788e-08 388 6.982e-06 3 Olfactory transduction www.genome.jp/d...
KEGG 04610 View Gene Set 1.933e-07 69 1.034e-05 4 Complement and coagulation cascades www.genome.jp/d...
KEGG 04514 View Gene Set 8.579e-06 135 0.0003672 5 Cell adhesion molecules (CAMs) www.genome.jp/d...
KEGG 04672 View Gene Set 3.202e-05 49 0.001142 6 Intestinal immune network for IgA production www.genome.jp/d...
KEGG 04640 View Gene Set 6.074e-05 88 0.001737 7 Hematopoietic cell lineage www.genome.jp/d...
KEGG 04950 View Gene Set 6.492e-05 25 0.001737 7 Maturity onset diabetes of the young www.genome.jp/d...
KEGG 04020 View Gene Set 9.261e-05 178 0.002202 9 Calcium signaling pathway www.genome.jp/d...
KEGG 04630 View Gene Set 0.0008641 155 0.01849 10 Jak-STAT signaling pathway www.genome.jp/d...
KEGG 05144 View Gene Set 0.001087 51 0.02114 11 Malaria www.genome.jp/d...
KEGG 04512 View Gene Set 0.001951 84 0.03479 12 ECM-receptor interaction www.genome.jp/d...
KEGG 05310 View Gene Set 0.002947 31 0.04852 13 Asthma www.genome.jp/d...

Gene Set Collection: GO

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
GO GO:0005576 View Gene Set 5.947e-58 2036 7.945e-54 1 extracellular region amigo.geneontol...
GO GO:0032501 View Gene Set 1.437e-44 4631 9.598e-41 2 multicellular organismal process amigo.geneontol...
GO GO:0044421 View Gene Set 3.806e-41 1001 1.695e-37 3 extracellular region part amigo.geneontol...
GO GO:0005886 View Gene Set 1.294e-36 3759 4.322e-33 4 plasma membrane amigo.geneontol...
GO GO:0004872 View Gene Set 6.061e-33 1688 1.62e-29 5 receptor activity amigo.geneontol...
GO GO:0004871 View Gene Set 2.518e-30 2128 4.805e-27 6 signal transducer activity amigo.geneontol...
GO GO:0060089 View Gene Set 2.518e-30 2128 4.805e-27 6 molecular transducer activity amigo.geneontol...
GO GO:0004888 View Gene Set 4.701e-30 1275 7.851e-27 8 transmembrane receptor activity amigo.geneontol...
GO GO:0005615 View Gene Set 8.991e-29 752 1.335e-25 9 extracellular space amigo.geneontol...
GO GO:0003008 View Gene Set 1.445e-26 1632 1.931e-23 10 system process amigo.geneontol...
GO GO:0050877 View Gene Set 2.491e-24 1272 3.026e-21 11 neurological system process amigo.geneontol...
GO GO:0031012 View Gene Set 3.905e-24 371 4.348e-21 12 extracellular matrix amigo.geneontol...
GO GO:0044459 View Gene Set 7.177e-23 2023 7.376e-20 13 plasma membrane part amigo.geneontol...
GO GO:0007275 View Gene Set 1.006e-21 3067 9.601e-19 14 multicellular organismal development amigo.geneontol...
GO GO:0048731 View Gene Set 1.737e-20 2544 1.547e-17 15 system development amigo.geneontol...
GO GO:0004930 View Gene Set 7.032e-20 855 5.871e-17 16 G-protein coupled receptor activity amigo.geneontol...
GO GO:0007267 View Gene Set 9.046e-20 720 7.109e-17 17 cell-cell signaling amigo.geneontol...
GO GO:0048856 View Gene Set 2.327e-19 2763 1.727e-16 18 anatomical structure development amigo.geneontol...
GO GO:0032502 View Gene Set 1.127e-18 3351 7.922e-16 19 developmental process amigo.geneontol...
GO GO:0007166 View Gene Set 4.324e-18 1497 2.626e-15 20 cell surface receptor linked signaling pathway amigo.geneontol...
GO GO:0030154 View Gene Set 4.181e-18 1834 2.626e-15 20 cell differentiation amigo.geneontol...
GO GO:0005578 View Gene Set 4.148e-18 313 2.626e-15 20 proteinaceous extracellular matrix amigo.geneontol...
GO GO:0031226 View Gene Set 4.646e-18 1208 2.698e-15 23 intrinsic to plasma membrane amigo.geneontol...
GO GO:0048869 View Gene Set 2.605e-17 1883 1.45e-14 24 cellular developmental process amigo.geneontol...
GO GO:0005887 View Gene Set 3.15e-17 1186 1.684e-14 25 integral to plasma membrane amigo.geneontol...
GO GO:0007186 View Gene Set 6.758e-17 543 3.473e-14 26 G-protein coupled receptor protein signaling pathway amigo.geneontol...
GO GO:0007600 View Gene Set 2.101e-15 830 1.039e-12 27 sensory perception amigo.geneontol...
GO GO:0007155 View Gene Set 7.91e-15 827 3.774e-12 28 cell adhesion amigo.geneontol...
GO GO:0009611 View Gene Set 8.814e-15 621 4.061e-12 29 response to wounding amigo.geneontol...
GO GO:0022610 View Gene Set 1.146e-14 828 5.104e-12 30 biological adhesion amigo.geneontol...
GO GO:0051239 View Gene Set 3.247e-14 1088 1.399e-11 31 regulation of multicellular organismal process amigo.geneontol...
GO GO:0048513 View Gene Set 9.102e-14 1931 3.75e-11 32 organ development amigo.geneontol...
GO GO:0005216 View Gene Set 9.264e-14 382 3.75e-11 32 ion channel activity amigo.geneontol...
GO GO:0007610 View Gene Set 1.248e-13 492 4.903e-11 34 behavior amigo.geneontol...
GO GO:0007399 View Gene Set 1.367e-13 1174 5.219e-11 35 nervous system development amigo.geneontol...
GO GO:0022836 View Gene Set 1.501e-13 309 5.569e-11 36 gated channel activity amigo.geneontol...
GO GO:0031224 View Gene Set 2.357e-13 5387 8.511e-11 37 intrinsic to membrane amigo.geneontol...
GO GO:0022803 View Gene Set 2.679e-13 410 9.418e-11 38 passive transmembrane transporter activity amigo.geneontol...
GO GO:0022838 View Gene Set 2.959e-13 393 1.014e-10 39 substrate-specific channel activity amigo.geneontol...
GO GO:0015267 View Gene Set 3.725e-13 409 1.244e-10 40 channel activity amigo.geneontol...
GO GO:0005261 View Gene Set 5.635e-13 271 1.836e-10 41 cation channel activity amigo.geneontol...
GO GO:0023052 View Gene Set 5.87e-13 3571 1.867e-10 42 signaling amigo.geneontol...
GO GO:0002376 View Gene Set 2.303e-12 1101 7.156e-10 43 immune system process amigo.geneontol...
GO GO:0006955 View Gene Set 2.735e-12 732 8.305e-10 44 immune response amigo.geneontol...
GO GO:0006954 View Gene Set 7.535e-12 380 2.237e-09 45 inflammatory response amigo.geneontol...
GO GO:0006952 View Gene Set 1.864e-11 717 5.414e-09 46 defense response amigo.geneontol...
GO GO:0007154 View Gene Set 1.924e-11 1687 5.469e-09 47 cell communication amigo.geneontol...
GO GO:0009653 View Gene Set 6.725e-11 1301 1.872e-08 48 anatomical structure morphogenesis amigo.geneontol...
GO GO:0016021 View Gene Set 7.732e-11 5278 2.108e-08 49 integral to membrane amigo.geneontol...
GO GO:0005201 View Gene Set 1.515e-10 81 4.047e-08 50 extracellular matrix structural constituent amigo.geneontol...
GO GO:0044425 View Gene Set 1.863e-10 6145 4.882e-08 51 membrane part amigo.geneontol...
GO GO:0006875 View Gene Set 2.547e-10 215 6.544e-08 52 cellular metal ion homeostasis amigo.geneontol...
GO GO:0031225 View Gene Set 2.927e-10 133 7.377e-08 53 anchored to membrane amigo.geneontol...
GO GO:0005125 View Gene Set 3.058e-10 201 7.566e-08 54 cytokine activity amigo.geneontol...
GO GO:0007626 View Gene Set 5.427e-10 300 1.318e-07 55 locomotory behavior amigo.geneontol...
GO GO:0007606 View Gene Set 1.299e-09 478 3.099e-07 56 sensory perception of chemical stimulus amigo.geneontol...
GO GO:0019226 View Gene Set 1.386e-09 421 3.248e-07 57 transmission of nerve impulse amigo.geneontol...
GO GO:0007268 View Gene Set 1.45e-09 362 3.34e-07 58 synaptic transmission amigo.geneontol...
GO GO:0022843 View Gene Set 1.485e-09 143 3.362e-07 59 voltage-gated cation channel activity amigo.geneontol...
GO GO:0055065 View Gene Set 1.806e-09 225 4.022e-07 60 metal ion homeostasis amigo.geneontol...
GO GO:0001775 View Gene Set 2.118e-09 389 4.64e-07 61 cell activation amigo.geneontol...
GO GO:0040011 View Gene Set 2.909e-09 617 6.268e-07 62 locomotion amigo.geneontol...
GO GO:0043062 View Gene Set 3.705e-09 174 7.857e-07 63 extracellular structure organization amigo.geneontol...
GO GO:0001501 View Gene Set 4.135e-09 277 8.547e-07 64 skeletal system development amigo.geneontol...
GO GO:0044057 View Gene Set 4.158e-09 315 8.547e-07 64 regulation of system process amigo.geneontol...
GO GO:0048699 View Gene Set 4.607e-09 601 9.327e-07 66 generation of neurons amigo.geneontol...
GO GO:0006874 View Gene Set 5.082e-09 204 1.013e-06 67 cellular calcium ion homeostasis amigo.geneontol...
GO GO:0022008 View Gene Set 5.943e-09 646 1.168e-06 68 neurogenesis amigo.geneontol...
GO GO:0009888 View Gene Set 6.167e-09 827 1.194e-06 69 tissue development amigo.geneontol...
GO GO:0030182 View Gene Set 6.633e-09 546 1.266e-06 70 neuron differentiation amigo.geneontol...
GO GO:0007608 View Gene Set 6.997e-09 432 1.317e-06 71 sensory perception of smell amigo.geneontol...
GO GO:0007204 View Gene Set 7.535e-09 134 1.398e-06 72 elevation of cytosolic calcium ion concentration amigo.geneontol...
GO GO:0030246 View Gene Set 8.679e-09 367 1.588e-06 73 carbohydrate binding amigo.geneontol...
GO GO:0006873 View Gene Set 8.8e-09 405 1.589e-06 74 cellular ion homeostasis amigo.geneontol...
GO GO:0055074 View Gene Set 1.011e-08 211 1.8e-06 75 calcium ion homeostasis amigo.geneontol...
GO GO:0004984 View Gene Set 1.161e-08 419 2.041e-06 76 olfactory receptor activity amigo.geneontol...
GO GO:0009605 View Gene Set 1.222e-08 666 2.106e-06 77 response to external stimulus amigo.geneontol...
GO GO:0055082 View Gene Set 1.23e-08 411 2.106e-06 77 cellular chemical homeostasis amigo.geneontol...
GO GO:0023060 View Gene Set 1.251e-08 2571 2.115e-06 79 signal transmission amigo.geneontol...
GO GO:0023046 View Gene Set 1.338e-08 2577 2.235e-06 80 signaling process amigo.geneontol...
GO GO:0005244 View Gene Set 1.437e-08 190 2.341e-06 81 voltage-gated ion channel activity amigo.geneontol...
GO GO:0022832 View Gene Set 1.437e-08 190 2.341e-06 81 voltage-gated channel activity amigo.geneontol...
GO GO:0034702 View Gene Set 1.645e-08 210 2.648e-06 83 ion channel complex amigo.geneontol...
GO GO:0051480 View Gene Set 1.712e-08 143 2.723e-06 84 cytosolic calcium ion homeostasis amigo.geneontol...
GO GO:0003013 View Gene Set 2.097e-08 250 3.258e-06 85 circulatory system process amigo.geneontol...
GO GO:0008015 View Gene Set 2.097e-08 250 3.258e-06 85 blood circulation amigo.geneontol...
GO GO:0030198 View Gene Set 2.707e-08 103 4.156e-06 87 extracellular matrix organization amigo.geneontol...
GO GO:0050801 View Gene Set 2.79e-08 441 4.235e-06 88 ion homeostasis amigo.geneontol...
GO GO:0001871 View Gene Set 4.021e-08 166 5.969e-06 89 pattern binding amigo.geneontol...
GO GO:0030247 View Gene Set 4.021e-08 166 5.969e-06 89 polysaccharide binding amigo.geneontol...
GO GO:0048468 View Gene Set 4.272e-08 804 6.272e-06 91 cell development amigo.geneontol...
GO GO:0048878 View Gene Set 4.44e-08 563 6.447e-06 92 chemical homeostasis amigo.geneontol...
GO GO:0002684 View Gene Set 6.06e-08 274 8.706e-06 93 positive regulation of immune system process amigo.geneontol...
GO GO:0032101 View Gene Set 6.389e-08 190 9.081e-06 94 regulation of response to external stimulus amigo.geneontol...
GO GO:0042060 View Gene Set 9.248e-08 223 1.301e-05 95 wound healing amigo.geneontol...
GO GO:0051241 View Gene Set 1.046e-07 191 1.456e-05 96 negative regulation of multicellular organismal process amigo.geneontol...
GO GO:0015276 View Gene Set 1.175e-07 128 1.601e-05 97 ligand-gated ion channel activity amigo.geneontol...
GO GO:0022834 View Gene Set 1.175e-07 128 1.601e-05 97 ligand-gated channel activity amigo.geneontol...
GO GO:0045321 View Gene Set 2.059e-07 342 2.778e-05 99 leukocyte activation amigo.geneontol...
GO GO:0046649 View Gene Set 2.905e-07 283 3.881e-05 100 lymphocyte activation amigo.geneontol...
GO GO:0051046 View Gene Set 3.42e-07 243 4.524e-05 101 regulation of secretion amigo.geneontol...
GO GO:0003002 View Gene Set 3.713e-07 226 4.863e-05 102 regionalization amigo.geneontol...
GO GO:0050865 View Gene Set 3.819e-07 191 4.954e-05 103 regulation of cell activation amigo.geneontol...
GO GO:0051240 View Gene Set 4.428e-07 283 5.689e-05 104 positive regulation of multicellular organismal process amigo.geneontol...
GO GO:0005102 View Gene Set 5.156e-07 928 6.56e-05 105 receptor binding amigo.geneontol...
GO GO:0002682 View Gene Set 6.193e-07 425 7.805e-05 106 regulation of immune system process amigo.geneontol...
GO GO:0009897 View Gene Set 6.413e-07 140 8.008e-05 107 external side of plasma membrane amigo.geneontol...
GO GO:0007596 View Gene Set 1.01e-06 128 0.0001249 108 blood coagulation amigo.geneontol...
GO GO:0030005 View Gene Set 1.131e-06 250 0.0001383 109 cellular di- tri-valent inorganic cation homeostasis amigo.geneontol...
GO GO:0008083 View Gene Set 1.138e-06 161 0.0001383 109 growth factor activity amigo.geneontol...
GO GO:0048870 View Gene Set 1.198e-06 495 0.0001429 111 cell motility amigo.geneontol...
GO GO:0051674 View Gene Set 1.198e-06 495 0.0001429 111 localization of cell amigo.geneontol...
GO GO:0048705 View Gene Set 1.261e-06 123 0.0001491 113 skeletal system morphogenesis amigo.geneontol...
GO GO:0005539 View Gene Set 1.278e-06 151 0.0001498 114 glycosaminoglycan binding amigo.geneontol...
GO GO:0055066 View Gene Set 1.327e-06 264 0.0001542 115 di- tri-valent inorganic cation homeostasis amigo.geneontol...
GO GO:0005267 View Gene Set 1.401e-06 130 0.0001613 116 potassium channel activity amigo.geneontol...
GO GO:0003001 View Gene Set 1.511e-06 187 0.00017 117 generation of a signal involved in cell-cell signaling amigo.geneontol...
GO GO:0023061 View Gene Set 1.511e-06 187 0.00017 117 signal release amigo.geneontol...
GO GO:0005581 View Gene Set 1.515e-06 35 0.00017 117 collagen amigo.geneontol...
GO GO:0045165 View Gene Set 1.548e-06 143 0.0001724 120 cell fate commitment amigo.geneontol...
GO GO:0042995 View Gene Set 1.579e-06 766 0.0001744 121 cell projection amigo.geneontol...
GO GO:0002541 View Gene Set 1.658e-06 44 0.0001816 122 activation of plasma proteins involved in acute inflammatory response amigo.geneontol...
GO GO:0006935 View Gene Set 1.693e-06 199 0.0001823 123 chemotaxis amigo.geneontol...
GO GO:0007389 View Gene Set 1.705e-06 285 0.0001823 123 pattern specification process amigo.geneontol...
GO GO:0042330 View Gene Set 1.693e-06 199 0.0001823 123 taxis amigo.geneontol...
GO GO:0050817 View Gene Set 1.854e-06 131 0.0001965 126 coagulation amigo.geneontol...
GO GO:0004497 View Gene Set 2.066e-06 93 0.0002174 127 monooxygenase activity amigo.geneontol...
GO GO:0006811 View Gene Set 2.086e-06 829 0.0002178 128 ion transport amigo.geneontol...
GO GO:0030193 View Gene Set 2.193e-06 40 0.0002254 129 regulation of blood coagulation amigo.geneontol...
GO GO:0030054 View Gene Set 2.179e-06 539 0.0002254 129 cell junction amigo.geneontol...
GO GO:0007423 View Gene Set 2.452e-06 251 0.0002501 131 sensory organ development amigo.geneontol...
GO GO:0048562 View Gene Set 2.62e-06 138 0.0002652 132 embryonic organ morphogenesis amigo.geneontol...
GO GO:0051094 View Gene Set 2.987e-06 352 0.000299 133 positive regulation of developmental process amigo.geneontol...
GO GO:0015075 View Gene Set 2.999e-06 715 0.000299 133 ion transmembrane transporter activity amigo.geneontol...
GO GO:0044420 View Gene Set 3.086e-06 112 0.0003054 135 extracellular matrix part amigo.geneontol...
GO GO:0009187 View Gene Set 3.195e-06 147 0.0003138 136 cyclic nucleotide metabolic process amigo.geneontol...
GO GO:0005179 View Gene Set 3.23e-06 108 0.000315 137 hormone activity amigo.geneontol...
GO GO:0021953 View Gene Set 3.381e-06 73 0.0003273 138 central nervous system neuron differentiation amigo.geneontol...
GO GO:0034703 View Gene Set 3.453e-06 136 0.0003319 139 cation channel complex amigo.geneontol...
GO GO:0007599 View Gene Set 3.636e-06 134 0.000347 140 hemostasis amigo.geneontol...
GO GO:0030199 View Gene Set 3.92e-06 27 0.0003715 141 collagen fibril organization amigo.geneontol...
GO GO:0006816 View Gene Set 4.114e-06 196 0.0003871 142 calcium ion transport amigo.geneontol...
GO GO:0055080 View Gene Set 4.35e-06 310 0.0004064 143 cation homeostasis amigo.geneontol...
GO GO:0005230 View Gene Set 4.422e-06 73 0.0004102 144 extracellular ligand-gated ion channel activity amigo.geneontol...
GO GO:0006928 View Gene Set 4.761e-06 653 0.0004387 145 cellular component movement amigo.geneontol...
GO GO:0030003 View Gene Set 5.107e-06 277 0.0004673 146 cellular cation homeostasis amigo.geneontol...
GO GO:0033267 View Gene Set 5.452e-06 71 0.0004955 147 axon part amigo.geneontol...
GO GO:0050896 View Gene Set 6.339e-06 3765 0.0005722 148 response to stimulus amigo.geneontol...
GO GO:0046058 View Gene Set 6.617e-06 124 0.0005933 149 cAMP metabolic process amigo.geneontol...
GO GO:0005509 View Gene Set 6.714e-06 626 0.000598 150 calcium ion binding amigo.geneontol...
GO GO:0061041 View Gene Set 7.017e-06 44 0.0006088 151 regulation of wound healing amigo.geneontol...
GO GO:0009986 View Gene Set 6.999e-06 350 0.0006088 151 cell surface amigo.geneontol...
GO GO:0001653 View Gene Set 6.988e-06 113 0.0006088 151 peptide receptor activity amigo.geneontol...
GO GO:0008528 View Gene Set 6.988e-06 113 0.0006088 151 peptide receptor activity G-protein coupled amigo.geneontol...
GO GO:2000026 View Gene Set 7.221e-06 625 0.0006224 155 regulation of multicellular organismal development amigo.geneontol...
GO GO:0006959 View Gene Set 7.999e-06 85 0.000685 156 humoral immune response amigo.geneontol...
GO GO:0000904 View Gene Set 8.723e-06 305 0.0007375 157 cell morphogenesis involved in differentiation amigo.geneontol...
GO GO:0016477 View Gene Set 8.686e-06 462 0.0007375 157 cell migration amigo.geneontol...
GO GO:0009887 View Gene Set 9.565e-06 659 0.0007937 159 organ morphogenesis amigo.geneontol...
GO GO:0051093 View Gene Set 9.492e-06 288 0.0007937 159 negative regulation of developmental process amigo.geneontol...
GO GO:0043195 View Gene Set 9.537e-06 26 0.0007937 159 terminal button amigo.geneontol...
GO GO:0005126 View Gene Set 9.749e-06 187 0.000804 162 cytokine receptor binding amigo.geneontol...
GO GO:0002694 View Gene Set 9.934e-06 179 0.0008142 163 regulation of leukocyte activation amigo.geneontol...
GO GO:0016020 View Gene Set 1.013e-05 7286 0.0008256 164 membrane amigo.geneontol...
GO GO:0048583 View Gene Set 1.042e-05 545 0.0008436 165 regulation of response to stimulus amigo.geneontol...
GO GO:0050795 View Gene Set 1.058e-05 69 0.0008467 166 regulation of behavior amigo.geneontol...
GO GO:0045202 View Gene Set 1.058e-05 371 0.0008467 166 synapse amigo.geneontol...
GO GO:0044456 View Gene Set 1.119e-05 274 0.0008903 168 synapse part amigo.geneontol...
GO GO:0046903 View Gene Set 1.354e-05 502 0.00107 169 secretion amigo.geneontol...
GO GO:0048666 View Gene Set 1.396e-05 399 0.001097 170 neuron development amigo.geneontol...
GO GO:0070838 View Gene Set 1.44e-05 203 0.001125 171 divalent metal ion transport amigo.geneontol...
GO GO:0009914 View Gene Set 1.465e-05 121 0.001134 172 hormone transport amigo.geneontol...
GO GO:0030855 View Gene Set 1.468e-05 194 0.001134 172 epithelial cell differentiation amigo.geneontol...
GO GO:0005249 View Gene Set 1.553e-05 97 0.001193 174 voltage-gated potassium channel activity amigo.geneontol...
GO GO:0006956 View Gene Set 1.648e-05 41 0.001258 175 complement activation amigo.geneontol...
GO GO:0050793 View Gene Set 1.709e-05 748 0.001298 176 regulation of developmental process amigo.geneontol...
GO GO:0050867 View Gene Set 1.745e-05 121 0.001317 177 positive regulation of cell activation amigo.geneontol...
GO GO:0009190 View Gene Set 1.929e-05 128 0.001447 178 cyclic nucleotide biosynthetic process amigo.geneontol...
GO GO:0001664 View Gene Set 2.084e-05 139 0.001555 179 G-protein-coupled receptor binding amigo.geneontol...
GO GO:0007417 View Gene Set 2.175e-05 463 0.0016 180 central nervous system development amigo.geneontol...
GO GO:0043005 View Gene Set 2.179e-05 371 0.0016 180 neuron projection amigo.geneontol...
GO GO:0045211 View Gene Set 2.174e-05 155 0.0016 180 postsynaptic membrane amigo.geneontol...
GO GO:0050818 View Gene Set 2.212e-05 44 0.001615 183 regulation of coagulation amigo.geneontol...
GO GO:0048584 View Gene Set 2.343e-05 284 0.001701 184 positive regulation of response to stimulus amigo.geneontol...
GO GO:0007411 View Gene Set 2.463e-05 97 0.001778 185 axon guidance amigo.geneontol...
GO GO:0019955 View Gene Set 2.573e-05 113 0.001848 186 cytokine binding amigo.geneontol...
GO GO:0000902 View Gene Set 2.73e-05 380 0.00195 187 cell morphogenesis amigo.geneontol...
GO GO:0030799 View Gene Set 2.751e-05 125 0.001955 188 regulation of cyclic nucleotide metabolic process amigo.geneontol...
GO GO:0042110 View Gene Set 2.793e-05 196 0.001964 189 T cell activation amigo.geneontol...
GO GO:0048568 View Gene Set 2.782e-05 214 0.001964 189 embryonic organ development amigo.geneontol...
GO GO:0050778 View Gene Set 2.869e-05 161 0.002007 191 positive regulation of immune response amigo.geneontol...
GO GO:0060401 View Gene Set 2.891e-05 48 0.002011 192 cytosolic calcium ion transport amigo.geneontol...
GO GO:0016337 View Gene Set 2.907e-05 318 0.002013 193 cell-cell adhesion amigo.geneontol...
GO GO:0005882 View Gene Set 3.355e-05 178 0.00231 194 intermediate filament amigo.geneontol...
GO GO:0032940 View Gene Set 3.396e-05 392 0.002327 195 secretion by cell amigo.geneontol...
GO GO:0006171 View Gene Set 3.506e-05 114 0.002365 196 cAMP biosynthetic process amigo.geneontol...
GO GO:0030802 View Gene Set 3.523e-05 120 0.002365 196 regulation of cyclic nucleotide biosynthetic process amigo.geneontol...
GO GO:0030808 View Gene Set 3.523e-05 120 0.002365 196 regulation of nucleotide biosynthetic process amigo.geneontol...
GO GO:0048663 View Gene Set 3.479e-05 39 0.002365 196 neuron fate commitment amigo.geneontol...
GO GO:0008201 View Gene Set 3.686e-05 113 0.002462 200 heparin binding amigo.geneontol...

Gene Set Collection: Broad.c2.CGP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad BENPORATH_ES_WITH_H3K27ME3 View Gene Set 2.935e-63 1094 7.02e-60 1 Set 'H3K27 bound': genes posessing the trimethylated H3K27 (H3K27me3) mark in their promoters in human embryonic stem cells as identified by ChIP on chip. www.broad.mit.e...
Broad BENPORATH_SUZ12_TARGETS View Gene Set 1.366e-50 1011 1.634e-47 2 Set 'Suz12 targets': genes identified by ChIP on chip as targets of the Polycomb protein SUZ12 [Gene ID=23512] in human embryonic stem cells. www.broad.mit.e...
Broad BENPORATH_PRC2_TARGETS View Gene Set 9.183e-42 636 7.322e-39 3 Set 'PRC2 targets': Polycomb Repression Complex 2 (PRC) targets; identified by ChIP on chip on human embryonic stem cells as genes that: posess the trimethylated H3K27 mark in their promoters and are bound by SUZ12 [Gene ID=23512] and EED [Gene ID=8726] Polycomb proteins. www.broad.mit.e...
Broad BENPORATH_EED_TARGETS View Gene Set 2.535e-37 1033 1.516e-34 4 Set 'Eed targets': genes identified by ChIP on chip as targets of the Polycomb protein EED [Gene ID=8726] in human embryonic stem cells. www.broad.mit.e...
Broad SMID_BREAST_CANCER_NORMAL_LIKE_UP View Gene Set 1.675e-30 459 8.013e-28 5 Genes up-regulated in the normal-like subtype of breast cancer. www.broad.mit.e...
Broad SMID_BREAST_CANCER_LUMINAL_B_DN View Gene Set 1.639e-22 549 6.533e-20 6 Genes down-regulated in the luminal B subtype of breast cancer. www.broad.mit.e...
Broad ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN View Gene Set 1.027e-19 882 3.509e-17 7 Genes whose DNA is hyper-methylated in hepatocellular carcinoma (HCC) compared to normal liver. www.broad.mit.e...
Broad LIU_PROSTATE_CANCER_DN View Gene Set 1.212e-19 446 3.624e-17 8 Genes down-regulated in prostate cancer samples. www.broad.mit.e...
Broad RIGGI_EWING_SARCOMA_PROGENITOR_UP View Gene Set 2.637e-18 399 7.008e-16 9 Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [Gene ID=2130 2321] fusion protein. www.broad.mit.e...
Broad SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP View Gene Set 1.261e-17 339 3.016e-15 10 Genes up-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS non-invasive). www.broad.mit.e...
Broad LINDGREN_BLADDER_CANCER_CLUSTER_2B View Gene Set 1.448e-17 384 3.148e-15 11 Genes specifically up-regulated in Cluster IIb of urothelial cell carcinom (UCC) tumors. www.broad.mit.e...
Broad HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP View Gene Set 2.252e-15 399 4.489e-13 12 Genes up-regulated in multiple myeloma (MM) cell lines treated with both decitabine [PubChem=451668] TSA [PubChem=5562]. www.broad.mit.e...
Broad SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 View Gene Set 1.443e-14 407 2.655e-12 13 Genes up-regulated in the pancreatic cancer cell lines (AsPC1 Hs766T MiaPaCa2 Panc1) but not in the non-neoplastic cells (HPDE) by decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. www.broad.mit.e...
Broad WALLACE_PROSTATE_CANCER_RACE_UP View Gene Set 1.754e-14 288 2.997e-12 14 Genes up-regulated in prostate cancer samples from African-American patients compared to those from the European-American patients. www.broad.mit.e...
Broad SHEN_SMARCA2_TARGETS_DN View Gene Set 2.531e-13 334 4.036e-11 15 Genes whose expression negatively correlated with that of SMARCA2 [Gene ID=6595] in prostate cancer samples. www.broad.mit.e...
Broad DODD_NASOPHARYNGEAL_CARCINOMA_UP View Gene Set 4.363e-13 1582 6.522e-11 16 Genes up-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. www.broad.mit.e...
Broad MCLACHLAN_DENTAL_CARIES_DN View Gene Set 5.49e-12 234 7.724e-10 17 Genes down-regulated in pulpal tissue extracted from carious teeth. www.broad.mit.e...
Broad VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP View Gene Set 3.482e-11 163 4.627e-09 18 Angiogenic markers up-regulated in lymph endothelial cells upon infection with KSHV (Kaposi's sarcoma herpes virus). www.broad.mit.e...
Broad ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP View Gene Set 8.216e-11 502 9.358e-09 19 Genes up-regulated in macrophages by P.gingivalis FimA pathogen. www.broad.mit.e...
Broad HELLER_HDAC_TARGETS_UP View Gene Set 7.845e-11 268 9.358e-09 19 Genes up-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]. www.broad.mit.e...
Broad MCLACHLAN_DENTAL_CARIES_UP View Gene Set 8.056e-11 207 9.358e-09 19 Genes up-regulated in pulpal tissue extracted from carious teeth. www.broad.mit.e...
Broad SABATES_COLORECTAL_ADENOMA_DN View Gene Set 5.708e-10 276 6.206e-08 22 Genes down-regulated in colorectal adenoma compared to normal mucosa samples. www.broad.mit.e...
Broad PEREZ_TP63_TARGETS View Gene Set 1.385e-09 328 1.44e-07 23 Genes up-regulated in the HMEC cells (primary mammary epithelium) upon expression of the transcriptionally active isoform of TP63 [Gene ID=8626] off adenoviral vector. www.broad.mit.e...
Broad HATADA_METHYLATED_IN_LUNG_CANCER_UP View Gene Set 7.864e-09 355 7.838e-07 24 Genes with hypermethylated DNA in lung cancer samples. www.broad.mit.e...
Broad ZHOU_INFLAMMATORY_RESPONSE_LPS_UP View Gene Set 1.841e-08 400 1.762e-06 25 Genes up-regulated in macrophages by P.gingivalis LPS (lipopolysaccharide). www.broad.mit.e...
Broad VECCHI_GASTRIC_CANCER_EARLY_DN View Gene Set 5.288e-08 346 4.826e-06 26 Down-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. www.broad.mit.e...
Broad CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN View Gene Set 5.447e-08 144 4.826e-06 26 Top 200 marker genes down-regulated in the 'CTNNB1' subclass of hepatocellular carcinoma (HCC); characterized by activated CTNNB1 [Gene ID=1499]. www.broad.mit.e...
Broad SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN View Gene Set 6.225e-08 296 5.318e-06 28 Genes down-regulated in nsopharyngeal carcinoma relative to the normal tissue. www.broad.mit.e...
Broad SWEET_LUNG_CANCER_KRAS_DN View Gene Set 3.479e-07 397 2.87e-05 29 Genes down-regulated in the mouse lung cancer model with mutated KRAS [Gene ID=3845]. www.broad.mit.e...
Broad KONDO_PROSTATE_CANCER_WITH_H3K27ME3 View Gene Set 3.963e-07 187 3.16e-05 30 Top 200 genes with high histone H3 trimethylation mark at K27 (H3K27me3) in PC3 cells (prostate cancer) by ChIP-chip assay on an 88K microarray (all promoters). www.broad.mit.e...
Broad PEREZ_TP53_TARGETS View Gene Set 4.57e-07 1066 3.526e-05 31 Genes up-regulated in the HMEC cells (primary mammary epithelium) upon expression of TP53 [Gene ID=7157] off adenoviral vector. www.broad.mit.e...
Broad TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN View Gene Set 5.95e-07 186 4.448e-05 32 Genes down-regulated in ductal carcinoma vs normal ductal breast cells. www.broad.mit.e...
Broad DELYS_THYROID_CANCER_DN View Gene Set 9.844e-07 213 7.135e-05 33 Genes down-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. www.broad.mit.e...
Broad SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN View Gene Set 1.197e-06 167 8.42e-05 34 Genes down-regulated in nasopharyngeal carcinoma (NPC) positive for LMP1 [Gene ID=9260] a latent gene of Epstein-Barr virus (EBV). www.broad.mit.e...
Broad SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER View Gene Set 1.277e-06 48 8.73e-05 35 50 most interesting genes up-regulated in pancreatic cancer cell lines (AsPC1 Hs766T MiaPaCa2 Panc1) but not in the non-neoplastic cells (HPDE) by TSA [PubChem=5562]. www.broad.mit.e...
Broad JAATINEN_HEMATOPOIETIC_STEM_CELL_DN View Gene Set 1.34e-06 215 8.905e-05 36 Genes up-regulated in CD133+ [Gene ID=8842] cells (hematopoietic stem cells HSC) compared to the CD133- cells. www.broad.mit.e...
Broad VERHAAK_AML_WITH_NPM1_MUTATED_DN View Gene Set 1.595e-06 241 0.0001031 37 Genes down-regulated in acute myeloid leukemia (AML) patients with mutated NPM1 [Gene ID=4869]. www.broad.mit.e...
Broad PEREZ_TP53_AND_TP63_TARGETS View Gene Set 2.545e-06 187 0.0001602 38 Genes up-regulated in HMEC cells (primary mammary epithelium) upon expression of both of TP53 [Gene ID=7157] and the transcriptionally active isoform of TP63 [Gene ID=8626] off adenoviral vectors. www.broad.mit.e...
Broad ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP View Gene Set 3.04e-06 458 0.0001865 39 Genes up-regulated in macrophage by live P.gingivalis. www.broad.mit.e...
Broad PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP View Gene Set 3.594e-06 197 0.0002149 40 Up-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes. www.broad.mit.e...
Broad EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP View Gene Set 4.68e-06 201 0.000273 41 Genes up-regulated in Rh4 cells (alveolar rhabdomyosarcoma ARMS) after knockdown of the PAX3-FOXO1 [Gene iD=5077 2308] fusion protein by RNAi for 72 hr. www.broad.mit.e...
Broad VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP View Gene Set 4.903e-06 159 0.0002792 42 Up-regulated genes distinguishing between two subtypes of gastric cancer: advanced (AGC) and early (EGC). www.broad.mit.e...
Broad GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP View Gene Set 5.522e-06 75 0.0003072 43 Up-regulated genes from the set E (Fig. 5a): specific signature shared by cells expressing either MLL-AF4 [Gene ID=4297 4299] or AF4-MLL fusion proteins alone and those expressing both fusion proteins. www.broad.mit.e...
Broad TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN View Gene Set 5.998e-06 64 0.0003261 44 Genes down-regulated in ductal carcinoma vs normal lobular breast cells. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP View Gene Set 1.141e-05 186 0.0006065 45 Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 10 days after transduction. www.broad.mit.e...
Broad CROONQUIST_STROMAL_STIMULATION_UP View Gene Set 1.167e-05 47 0.0006067 46 Genes up-regulated in ANBL-6 cell line (multiple myeloma MM) co-cultured with bone marrow stromal cells compared to those grown in the presence of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad MCGARVEY_SILENCED_BY_METHYLATION_IN_COLON_CANCER View Gene Set 1.346e-05 42 0.000685 47 Genes silenced in HCT116 cells (colon cancer) by methylation of CpG islands in their promoters. www.broad.mit.e...
Broad RICKMAN_HEAD_AND_NECK_CANCER_A View Gene Set 1.639e-05 91 0.0008169 48 Cluster a: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). www.broad.mit.e...
Broad ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP View Gene Set 1.702e-05 178 0.0008308 49 Genes up-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN View Gene Set 1.802e-05 192 0.0008621 50 Genes down-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 8 days after transduction. www.broad.mit.e...
Broad MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP View Gene Set 2.166e-05 365 0.001016 51 Genes distinguishing in multiple myeloma (MM) samples with higher expression of TACI [Gene ID=23495]. www.broad.mit.e...
Broad BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN View Gene Set 3.519e-05 45 0.001619 52 Genes down-regulated in the invasive ductal carcinoma (IDC) compared to the invasive lobular carcinoma (ILC) the two major pathological types of breast cancer. www.broad.mit.e...
Broad FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP View Gene Set 4.85e-05 86 0.002189 53 Genes differentially expressed in kidney biopsies from patients with acute transplant rejection compared to the biopsies from patients with well functioning kidneys more than 1-year post transplant. www.broad.mit.e...
Broad ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP View Gene Set 5.139e-05 280 0.002256 54 Genes whose promoters display higher levels of histone H3 trimethylation mark at K27 (H3K27me3) in hepatocellular carcinoma (HCC) compared to normal liver. www.broad.mit.e...
Broad GAURNIER_PSMD4_TARGETS View Gene Set 5.186e-05 59 0.002256 54 Inflammatory cytokines chemokines and their cognate receptors up-regulated in THP-1 cells (monocyte) after treatment with PSMD4 [Gene ID=5710]. www.broad.mit.e...
Broad SENGUPTA_EBNA1_ANTICORRELATED View Gene Set 6.083e-05 156 0.002598 56 Genes whose reduced expression in nasopharyngeal carinoma (NPC) correlated most with the increased expression of EBNA1 [Gene ID=3783774] a latent gene of Epstein-Barr virus (EBV). www.broad.mit.e...
Broad MANALO_HYPOXIA_UP View Gene Set 6.206e-05 197 0.002604 57 Genes up-regulated in response to both hypoxia and overexpression of an active form of HIF1A [Gene ID=3091]. www.broad.mit.e...
Broad SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER View Gene Set 6.436e-05 86 0.002654 58 Genes bearing H3K27me3 mark or whose promoters are bound by the polycomb proteins SUZ12 or EED [Gene ID=23512 8726]; their DNA is methylated de novo in cancer. www.broad.mit.e...
Broad VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN View Gene Set 7.097e-05 134 0.002877 59 Angiogenic markers down-regulated in lymph endothelial cells upon infection with KSHV (Kaposi's sarcoma herpes virus). www.broad.mit.e...
Broad ODONNELL_TFRC_TARGETS_UP View Gene Set 7.485e-05 401 0.002984 60 Genes up-regulated in P493-6 cells (B lymphocyte) upon knockdown of TFRC [Gene ID=7037] by RNAi. www.broad.mit.e...
Broad RICKMAN_HEAD_AND_NECK_CANCER_E View Gene Set 9.135e-05 83 0.003582 61 Cluster e: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). www.broad.mit.e...
Broad TAVAZOIE_METASTASIS View Gene Set 0.0001146 103 0.004422 62 Putative metastasis genes: up-regulated in metastatic cell lines LM2 (lung) and BoM2 (bone) relative to the parental MDA-MB-231 line (breast adenocarcinoma). www.broad.mit.e...
Broad RICKMAN_HEAD_AND_NECK_CANCER_C View Gene Set 0.0001197 107 0.004546 63 Cluster c: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). www.broad.mit.e...
Broad TOMLINS_PROSTATE_CANCER_DN View Gene Set 0.000143 39 0.005343 64 Genes down-regulated in prostate cancer vs benign prostate tissue based on a meta-analysis of five gene expression profiling studies. www.broad.mit.e...
Broad WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN View Gene Set 0.0001531 23 0.005633 65 Down-regulated genes characteristic for autonomous thyroid adenoma. www.broad.mit.e...
Broad CROMER_TUMORIGENESIS_UP View Gene Set 0.0001581 43 0.00573 66 Tumorigenesis markers of head and neck squamous cell carcinoma (HNSCC): up-regulated in the 'early' tumors vs normal samples. www.broad.mit.e...
Broad IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN View Gene Set 0.0001718 104 0.006133 67 Genes down-regulated in adipose tissue mesenchymal stem cells (ASC) vs bone marrow mesenchymal stem cells (rBMSC) www.broad.mit.e...
Broad HELLER_SILENCED_BY_METHYLATION_UP View Gene Set 0.0001769 247 0.006223 68 Genes up-regulated in at least one of three multiple myeloma (MM) cell lines treated with the DNA hypomethylating agent decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. www.broad.mit.e...
Broad WANG_SMARCE1_TARGETS_UP View Gene Set 0.0002012 158 0.006974 69 Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [Gene ID=6605] off a retroviral vector. www.broad.mit.e...
Broad WONG_ENDMETRIUM_CANCER_DN View Gene Set 0.0002106 42 0.007195 70 Genes down-regulated in cancer endometrium samples compared to the normal endometrium. www.broad.mit.e...
Broad LEE_NEURAL_CREST_STEM_CELL_UP View Gene Set 0.0002429 142 0.008185 71 Genes up-regulated in the neural crest stem cells (NCS) defined as p75+/HNK1+ [Gene ID=4804 27087]. www.broad.mit.e...
Broad CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 View Gene Set 0.0002535 377 0.008423 72 The 'group 2 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [Gene ID=2099 2064]. www.broad.mit.e...
Broad NAGASHIMA_EGF_SIGNALING_UP View Gene Set 0.0002755 57 0.009026 73 Genes up-regulated in MCF7 cells (breast cancer) after stimulation with EGF [Gene ID=1950]. www.broad.mit.e...
Broad KANG_IMMORTALIZED_BY_TERT_DN View Gene Set 0.000293 102 0.009471 74 Down-regulated genes in the signature of adipose stromal cells (ADSC) immortalized by forced expression of telomerase (TERT) [Gene ID=7015]. www.broad.mit.e...
Broad RICKMAN_HEAD_AND_NECK_CANCER_D View Gene Set 0.0003173 36 0.01012 75 Cluster d: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). www.broad.mit.e...
Broad DOANE_BREAST_CANCER_ESR1_DN View Gene Set 0.0003464 48 0.01089 76 Genes changed in breast cancer samples according to the ESR1 [Gene ID=2099] status: ER positive vs ER negative tumors. www.broad.mit.e...
Broad BOYLAN_MULTIPLE_MYELOMA_C_D_DN View Gene Set 0.0003506 232 0.01089 76 Genes down-regulated both in group C and D of tumors arising from overexpression of BCL2L1 and MYC [Gene ID=598 4609] in plasma cells. www.broad.mit.e...
Broad NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN View Gene Set 0.0003694 78 0.01133 78 Top 100 probe sets contrubuting to the negative side of the 2nd principal component; associated with adipocytic differentiation. www.broad.mit.e...
Broad HUPER_BREAST_BASAL_VS_LUMINAL_UP View Gene Set 0.000422 54 0.01262 79 Genes up-regulated in basal mammary epithelial cells compared to the luminal ones. www.broad.mit.e...
Broad POOLA_INVASIVE_BREAST_CANCER_UP View Gene Set 0.0004189 278 0.01262 79 Genes up-regulated in atypical ductal hyperplastic tissues from patients with (ADHC) breast cancer vs those without the cancer (ADH). www.broad.mit.e...
Broad MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN View Gene Set 0.0005037 64 0.01481 81 Down-regulated 'cooperation response genes': responded synergystically to the combination of mutant TP53 [Gene ID=7157] and HRAS [Gene ID=3265] in YAMC cells (colon). www.broad.mit.e...
Broad NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP View Gene Set 0.0005075 74 0.01481 81 Top 100 probe sets contrubuting to the positive side of the 1st principal component; predominantly associated with spindle cell and pleomorphic sarcoma samples. www.broad.mit.e...
Broad KHETCHOUMIAN_TRIM24_TARGETS_UP View Gene Set 0.0005174 45 0.01491 83 Retinoic acid-responsive genes up-regulated in hepatocellular carcinoma (HCC) samples of TRIM24 [Gene ID=8805] knockout mice. www.broad.mit.e...
Broad BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN View Gene Set 0.0005349 30 0.01523 84 Genes down-regulated in cultured stromal stem cells from adipose tissue compared to the freshly isolated cells. www.broad.mit.e...
Broad SENESE_HDAC1_AND_HDAC2_TARGETS_DN View Gene Set 0.0005638 218 0.01587 85 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of both HDAC1 and HDAC2 [Gene ID=3065 3066] by RNAi. www.broad.mit.e...
Broad CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN View Gene Set 0.0005794 444 0.01612 86 Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. www.broad.mit.e...
Broad WILENSKY_RESPONSE_TO_DARAPLADIB View Gene Set 0.0006057 27 0.01665 87 Atherosclerotic process genes whose coronary expression changed after darapladib [PubChem=9939609] treatment. www.broad.mit.e...
Broad BOYLAN_MULTIPLE_MYELOMA_PCA1_UP View Gene Set 0.0006128 80 0.01666 88 Top up-regulated genes from principal component 1 (PCA1) which captures variation between normal plasma cells and tumors arising from aberrant expression of BCL2L1 and MYC [Gene ID=598 4609]. www.broad.mit.e...
Broad SABATES_COLORECTAL_ADENOMA_UP View Gene Set 0.0006814 132 0.01818 89 Genes up-regulated in colorectal adenoma compared to normal mucosa samples. www.broad.mit.e...
Broad CHEBOTAEV_GR_TARGETS_DN View Gene Set 0.000684 118 0.01818 89 Genes down-regulated in follicular epithelial stem cells after transgenic expression of GR [Gene ID=2908] under control of the keratin5 (K5) [Gene ID=3852] promoter. www.broad.mit.e...
Broad SENESE_HDAC2_TARGETS_DN View Gene Set 0.0007752 124 0.02038 91 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC2 [Gene ID=3066] by RNAi. www.broad.mit.e...
Broad CHEN_HOXA5_TARGETS_6HR_UP View Gene Set 0.00103 10 0.02641 92 Differentially expressed genes 6 hr after tinduction of HoxA5 [Gene ID=3205] expression in a breast cancer cell line. www.broad.mit.e...
Broad ZHAN_MULTIPLE_MYELOMA_CD2_UP View Gene Set 0.001022 42 0.02641 92 Top 50 up-regulated genes in cluster CD-2 of multiple myeloma samples with the characteristic expression spike of CCND3 [Gene ID=896]. www.broad.mit.e...
Broad KUNINGER_IGF1_VS_PDGFB_TARGETS_UP View Gene Set 0.001038 42 0.02641 92 Genes up-regulated in C2AS12 cells (myoblast) by IGF1 [Gene ID=3479] vs PDGFB [Gene ID=5155]. www.broad.mit.e...
Broad PASTURAL_RIZ1_TARGETS_DN View Gene Set 0.001058 5 0.02663 95 Genes down-regulated in K562 (chronic myelogenous leukemia CML) cells engineered to stably express RIZ1 [Gene ID=7799]. www.broad.mit.e...
Broad DELYS_THYROID_CANCER_UP View Gene Set 0.001142 397 0.02845 96 Genes up-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. www.broad.mit.e...
Broad KOBAYASHI_EGFR_SIGNALING_6HR_DN View Gene Set 0.001171 18 0.02888 97 Genes down-regulated in H1975 cells (non-small cell lung cancer NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 6h. www.broad.mit.e...
Broad OSADA_ASCL1_TARGETS_UP View Gene Set 0.001209 46 0.02931 98 Genes up-regulated in A549 cells (lung cancer) upon expression of ASCL1 [Gene ID=429] off a viral vector. www.broad.mit.e...
Broad BEIER_GLIOMA_STEM_CELL_UP View Gene Set 0.001213 33 0.02931 98 Genes up-regulated in cancer stem cells derived from glyoblastoma tumors: CD133+ [Gene ID=8842] vs. CD133- cells. www.broad.mit.e...
Broad ODONNELL_METASTASIS_UP View Gene Set 0.001268 77 0.03034 100 Up-regulated genes in the signature set for lymph node metastasis in head and neck squamous cell carcinoma (HNSCC). www.broad.mit.e...
Broad SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 View Gene Set 0.00139 48 0.03293 101 50 most interesting genes up-regulated in the pancreatic cancer cell lines (AsPC1 Hs766T MiaPaCa2 Panc1) but not in the non-neoplastic cells (HPDE) by decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. www.broad.mit.e...
Broad DE_YY1_TARGETS_UP View Gene Set 0.001408 19 0.03302 102 Genes up-regulated in SaOS-2 cells (osteosarcoma) upon knockdown of YY1 [Gene ID=7528] by RNAi. www.broad.mit.e...
Broad VERHAAK_AML_WITH_NPM1_MUTATED_UP View Gene Set 0.001458 178 0.03387 103 Genes up-regulated in acute myeloid leukemia (AML) patients with mutated NPM1 [Gene ID=4869]. www.broad.mit.e...
Broad FURUKAWA_DUSP6_TARGETS_PCI35_UP View Gene Set 0.00149 64 0.03427 104 Genes up-regulated in PCI-35 cells (pancreatic cancer lack endogenous DUSP6 [Gene ID=1848]) upon expression of DUSP6 off an adenoviral vector. www.broad.mit.e...
Broad LEE_NEURAL_CREST_STEM_CELL_DN View Gene Set 0.001564 114 0.03564 105 Genes down-regulated in the neural crest stem cells (NCS) defined as p75+/HNK1+ [Gene ID=4804 27087]. www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_2HR_UP View Gene Set 0.001665 39 0.03757 106 Genes up-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 2 h time point that were not up-regulated at the previous time point 1 h. www.broad.mit.e...
Broad CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP View Gene Set 0.001693 138 0.03784 107 Top 200 marker genes up-regulated in the 'CTNNB1' subclass of hepatocellular carcinoma (HCC); characterized by activated CTNNB1 [Gene ID=1499]. www.broad.mit.e...
Broad TING_SILENCED_BY_DICER View Gene Set 0.00179 27 0.03965 108 Epigenetically silenced genes up-regulated in HCT116 cells (colon cancer) hypomorphic for DICER1 [Gene ID=23405]. www.broad.mit.e...
Broad WINTER_HYPOXIA_DN View Gene Set 0.001986 46 0.04277 109 Genes down-regulated in head and neck tumor samples which clustered around known hypoxia genes. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP View Gene Set 0.001989 174 0.04277 109 Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 3 days after transduction. www.broad.mit.e...
Broad SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 View Gene Set 0.002003 296 0.04277 109 Cluster 12 of method A: up-regulation of these genes in patients with non-small cell lung cancer (NSCLC) predicts good survival outcome. www.broad.mit.e...
Broad XU_GH1_EXOGENOUS_TARGETS_UP View Gene Set 0.00195 48 0.04277 109 Genes up-regulated in MFCF-7 cells (breast cancer) by exogenous HG1 [Gene ID=2688]. www.broad.mit.e...
Broad YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP View Gene Set 0.002022 130 0.0428 113 Genes up-regulated in mouse stroma of pancreatic adenocarcinoma zenografts after treatment with HhAntag a hedgehog (Hh) pathway inhibitor. www.broad.mit.e...
Broad MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_UP View Gene Set 0.002044 21 0.04288 114 Genes up-regulated in FSHD (facioscapulohumeral muscular dystrophy) mesoangioblasts. www.broad.mit.e...
Broad DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS View Gene Set 0.002183 5 0.04471 115 NF-kB-driven pro-inflammatory genes that are negatively regulated by glucocorticoids. www.broad.mit.e...
Broad YAMASHITA_METHYLATED_IN_PROSTATE_CANCER View Gene Set 0.002184 57 0.04471 115 Genes up-regulated in prostate cancer cell lines after treatment with 5-aza-2'-deoxycytidine (decitabine) [PubChem=451668]. www.broad.mit.e...
Broad NAKAMURA_METASTASIS_MODEL_DN View Gene Set 0.002187 41 0.04471 115 Top genes up-regulated in subcutaneous tumors from highly metastatic pancreatic cancer cells. www.broad.mit.e...
Broad CROONQUIST_NRAS_SIGNALING_UP View Gene Set 0.002216 32 0.04493 118 Genes up-regulated in ANBL-6 cell line (multiple myeloma MM) expressing a constantly active form of NRAS [Gene ID=4893] off a plasmid vector compared to those grown in the presence of IL6 [Gene ID=3569]. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP View Gene Set 0.002299 168 0.04501 119 Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 16 days after transduction. www.broad.mit.e...
Broad STREICHER_LSM1_TARGETS_DN View Gene Set 0.002265 19 0.04501 119 Genes down-regulated in MCF10A cells (breast cancer) by expression of LSM1 [Gene ID=27257] off a letiviral vector. www.broad.mit.e...
Broad NAKAMURA_ALVEOLAR_EPITHELIUM View Gene Set 0.002299 5 0.04501 119 Differentiation markers for normal alveolar epithelium cells. www.broad.mit.e...
Broad LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP View Gene Set 0.002315 79 0.04501 119 Genes up-regulated between two breast carcinoma subtypes: metaplastic (MCB) and ductal (DCB). www.broad.mit.e...
Broad CERVERA_SDHB_TARGETS_1_UP View Gene Set 0.002298 110 0.04501 119 Genes turned on in Hep3B cells (hepatocellular carcinoma HCC) upon knockdown of SDHB [Gene ID=6390] by RNAi. www.broad.mit.e...
Broad WANG_METHYLATED_IN_BREAST_CANCER View Gene Set 0.002338 32 0.04511 124 Genes up-regulated in MDA468 cells (breast cancer) vs DU99 cells (normal breast) after treatment with azacytidine [PubChem=9444]. www.broad.mit.e...
Broad ROY_WOUND_BLOOD_VESSEL_UP View Gene Set 0.002472 48 0.04693 125 Genes up-regulated in blood vessel cells from wound site. www.broad.mit.e...
Broad HUANG_FOXA2_TARGETS_DN View Gene Set 0.002455 36 0.04693 125 Genes down-regulated in H358 cells (lung cancer) by inducible expression of FOXA2 [GeneID=3170] in a Tet-off system. www.broad.mit.e...
Broad TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN View Gene Set 0.002507 138 0.04707 127 Genes down-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928 3205] off a retroviral vector at 10 days after transduction. www.broad.mit.e...
Broad GOZGIT_ESR1_TARGETS_DN View Gene Set 0.002539 710 0.04707 127 Genes down-regulated in TMX2-28 cells (breast cancer) which do not express ESR1 [Gene ID=2099]) compared to the parental MCF7 cells which do. www.broad.mit.e...
Broad LOPES_METHYLATED_IN_COLON_CANCER_UP View Gene Set 0.002531 23 0.04707 127 Genes methylated aberrantly in HCT116 and Colo320 (colon cancer) cells. www.broad.mit.e...
Broad FARMER_BREAST_CANCER_CLUSTER_5 View Gene Set 0.002632 19 0.04738 130 Cluster 5: selected 17q21_23 amplicon genes clustered together across breast cancer samples. www.broad.mit.e...
Broad RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP View Gene Set 0.002622 25 0.04738 130 ES/PNET (Ewing sarcoma; primitive neuroectodermal tumors) markers up-regulated in neuroblastoma cell lines expressing ESWR1-FLI1 [Gene ID=2130 2313] fusion protein. www.broad.mit.e...
Broad REN_ALVEOLAR_RHABDOMYOSARCOMA_UP View Gene Set 0.002654 95 0.04738 130 Genes commonly up-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [Gene ID=5077 2308] fusion. www.broad.mit.e...
Broad LIANG_SILENCED_BY_METHYLATION_2 View Gene Set 0.002609 35 0.04738 130 Genes up-regulated in T24 cells (bladder carcinoma) after treatment with decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. www.broad.mit.e...
Broad BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_UP View Gene Set 0.002635 19 0.04738 130 Genes up-regulated in D-341 MED (OBR) cells (medulloblastoma) resistant to both carmustine and O6-BG [PubChem=2578 4578]. www.broad.mit.e...
Broad SILIGAN_BOUND_BY_EWS_FLT1_FUSION View Gene Set 0.002812 36 0.04966 135 Genes bound by EWSR1-FLT1 [Gene ID=2130 2321] fusion but whose expression did not change in STA-ET-7.2 cells (Ewing's sarcoma) after knockdown of EWSR1-FLT1 by RNAi. www.broad.mit.e...
Broad HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP View Gene Set 0.002834 34 0.04966 135 Genes up-regulated in SCLC (small cell lung cancer) cells with acquired resistance to ABT-737 [PubChem=11228183] an inhibitor of the BCL2 [Gene ID=596] family proteins. www.broad.mit.e...
Broad SMID_BREAST_CANCER_LUMINAL_A_UP View Gene Set 0.002844 79 0.04966 135 Genes up-regulated in the luminal A subtype of breast cancer. www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.BIOCARTA

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad BIOCARTA_TCRA_PATHWAY View Gene Set 8.587e-05 13 0.01863 1 Lck and Fyn tyrosine kinases in initiation of TCR Activation www.broad.mit.e...
Broad BIOCARTA_INTRINSIC_PATHWAY View Gene Set 0.0007217 23 0.03915 2 Intrinsic Prothrombin Activation Pathway www.broad.mit.e...
Broad BIOCARTA_TCYTOTOXIC_PATHWAY View Gene Set 0.0003757 14 0.03915 2 T Cytotoxic Cell Surface Molecules www.broad.mit.e...
Broad BIOCARTA_THELPER_PATHWAY View Gene Set 0.0005938 14 0.03915 2 T Helper Cell Surface Molecules www.broad.mit.e...
Broad BIOCARTA_BLYMPHOCYTE_PATHWAY View Gene Set 0.001478 11 0.04129 5 B Lymphocyte Cell Surface Molecules www.broad.mit.e...
Broad BIOCARTA_COMP_PATHWAY View Gene Set 0.001347 19 0.04129 5 Complement Pathway www.broad.mit.e...
Broad BIOCARTA_IL17_PATHWAY View Gene Set 0.001522 17 0.04129 5 IL 17 Signaling Pathway www.broad.mit.e...
Broad BIOCARTA_NO2IL12_PATHWAY View Gene Set 0.001051 17 0.04129 5 NO2-dependent IL 12 Pathway in NK cells www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.KEGG

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION View Gene Set 1.961e-12 272 3.648e-10 1 Neuroactive ligand-receptor interaction www.broad.mit.e...
Broad KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION View Gene Set 2.558e-10 267 2.379e-08 2 Cytokine-cytokine receptor interaction www.broad.mit.e...
Broad KEGG_OLFACTORY_TRANSDUCTION View Gene Set 9.788e-08 389 6.069e-06 3 Olfactory transduction www.broad.mit.e...
Broad KEGG_COMPLEMENT_AND_COAGULATION_CASCADES View Gene Set 1.933e-07 69 8.989e-06 4 Complement and coagulation cascades www.broad.mit.e...
Broad KEGG_CELL_ADHESION_MOLECULES_CAMS View Gene Set 8.579e-06 134 0.0003191 5 Cell adhesion molecules (CAMs) www.broad.mit.e...
Broad KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION View Gene Set 3.202e-05 48 0.0009926 6 Intestinal immune network for IgA production www.broad.mit.e...
Broad KEGG_HEMATOPOIETIC_CELL_LINEAGE View Gene Set 6.074e-05 88 0.001509 7 Hematopoietic cell lineage www.broad.mit.e...
Broad KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG View Gene Set 6.492e-05 25 0.001509 7 Maturity onset diabetes of the young www.broad.mit.e...
Broad KEGG_CALCIUM_SIGNALING_PATHWAY View Gene Set 9.261e-05 178 0.001914 9 Calcium signaling pathway www.broad.mit.e...
Broad KEGG_JAK_STAT_SIGNALING_PATHWAY View Gene Set 0.0008641 155 0.01607 10 Jak-STAT signaling pathway www.broad.mit.e...
Broad KEGG_ECM_RECEPTOR_INTERACTION View Gene Set 0.001951 84 0.03298 11 ECM-receptor interaction www.broad.mit.e...
Broad KEGG_ASTHMA View Gene Set 0.002947 30 0.04569 12 Asthma www.broad.mit.e...
Broad KEGG_AUTOIMMUNE_THYROID_DISEASE View Gene Set 0.003356 53 0.04727 13 Autoimmune thyroid disease www.broad.mit.e...
Broad KEGG_GRAFT_VERSUS_HOST_DISEASE View Gene Set 0.003558 42 0.04727 13 Graft-versus-host disease www.broad.mit.e...

Gene Set Collection: Broad.c2.CP.REACTOME

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad REACTOME_GPCR_LIGAND_BINDING View Gene Set 2.051e-14 392 8.819e-12 1 Genes involved in GPCR ligand binding www.broad.mit.e...
Broad REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING View Gene Set 8.104e-13 448 1.742e-10 2 Genes involved in Downstream events in GPCR signaling www.broad.mit.e...
Broad REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS View Gene Set 9.529e-12 292 1.366e-09 3 Genes involved in Class A/1 (Rhodopsin-like receptors) www.broad.mit.e...
Broad REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS View Gene Set 6.971e-09 173 7.494e-07 4 Genes involved in Peptide ligand-binding receptors www.broad.mit.e...
Broad REACTOME_OLFACTORY_SIGNALING_PATHWAY View Gene Set 4.179e-08 371 3.594e-06 5 Genes involved in Olfactory Signaling Pathway www.broad.mit.e...
Broad REACTOME_G_ALPHA_I_SIGNALLING_EVENTS View Gene Set 5.573e-07 177 3.994e-05 6 Genes involved in G alpha (i) signalling events www.broad.mit.e...
Broad REACTOME_TRANSLOCATION_OF_ZAP70_TO_IMMUNOLOGICAL_SYNAPSE View Gene Set 3.55e-05 24 0.002181 7 Genes involved in Translocation of ZAP-70 to Immunological synapse www.broad.mit.e...
Broad REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE View Gene Set 4.265e-05 49 0.002293 8 Genes involved in Cytochrome P450 - arranged by substrate type www.broad.mit.e...
Broad REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS View Gene Set 8.274e-05 156 0.003558 9 Genes involved in G alpha (q) signalling events www.broad.mit.e...
Broad REACTOME_NCAM1_INTERACTIONS View Gene Set 7.926e-05 43 0.003558 9 Genes involved in NCAM1 interactions www.broad.mit.e...
Broad REACTOME_G_ALPHA_S_SIGNALLING_EVENTS View Gene Set 9.512e-05 126 0.003718 11 Genes involved in G alpha (s) signalling events www.broad.mit.e...
Broad REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES View Gene Set 0.0001139 37 0.003767 12 Genes involved in Generation of second messenger molecules www.broad.mit.e...
Broad REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS View Gene Set 0.0001104 26 0.003767 12 Genes involved in Phosphorylation of CD3 and TCR zeta chains www.broad.mit.e...
Broad REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS View Gene Set 0.0001681 18 0.005162 14 Genes involved in Na+/Cl- dependent neurotransmitter transporters www.broad.mit.e...
Broad REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES View Gene Set 0.000342 55 0.009191 15 Genes involved in Chemokine receptors bind chemokines www.broad.mit.e...
Broad REACTOME_CLASS_B2_SECRETIN_FAMILY_RECEPTORS View Gene Set 0.0003223 85 0.009191 15 Genes involved in Class B/2 (Secretin family receptors) www.broad.mit.e...
Broad REACTOME_PHASE_1_FUNCTIONALIZATION_OF_COMPOUNDS View Gene Set 0.000407 67 0.01029 17 Genes involved in Phase 1 - Functionalization of compounds www.broad.mit.e...
Broad REACTOME_CRMPS_IN_SEMA3A_SIGNALING View Gene Set 0.0004806 16 0.01148 18 Genes involved in CRMPs in Sema3A signaling www.broad.mit.e...
Broad REACTOME_COMPLEMENT_CASCADE View Gene Set 0.001178 50 0.02667 19 Genes involved in Complement cascade www.broad.mit.e...
Broad REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION View Gene Set 0.001326 14 0.02851 20 Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion www.broad.mit.e...
Broad REACTOME_PD1_SIGNALING View Gene Set 0.001395 29 0.02856 21 Genes involved in PD-1 signaling www.broad.mit.e...

Gene Set Collection: Broad.c3.TFT

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad V$RP58_01 View Gene Set 1.796e-08 179 1.105e-05 1 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNAACATCTGGA which matches annotation for ZNF238: zinc finger protein 238 www.broad.mit.e...
Broad TATAAA_V$TATA_01 View Gene Set 8.895e-08 1012 2.735e-05 2 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TATAAA which matches annotation for TAF<br> TATA www.broad.mit.e...
Broad V$AP4_Q6 View Gene Set 7.246e-07 170 0.0001312 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CWCAGCTGGN which matches annotation for TFAP4: transcription factor AP-4 (activating enhancer binding protein 4) www.broad.mit.e...
Broad V$LHX3_01 View Gene Set 8.532e-07 182 0.0001312 3 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif AATTAATTAA which matches annotation for LHX3: LIM homeobox 3 www.broad.mit.e...
Broad V$GATA_Q6 View Gene Set 2.654e-06 159 0.000272 5 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif WGATARN which matches annotation for GATA1: GATA binding protein 1 (globin transcription factor 1) www.broad.mit.e...
Broad CTAWWWATA_V$RSRFC4_Q2 View Gene Set 2.238e-06 283 0.000272 5 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CTAWWWATA which matches annotation for MEF2A: MADS box transcription enhancer factor 2 polypeptide A (myocyte enhancer factor 2A) www.broad.mit.e...
Broad V$NRSF_01 View Gene Set 4.942e-06 76 0.0004342 7 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTCAGCACCACGGACAGMGCC which matches annotation for REST: RE1-silencing transcription factor www.broad.mit.e...
Broad V$RSRFC4_01 View Gene Set 2.005e-05 192 0.001542 8 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RNKCTATTTWTAGMWN which matches annotation for MEF2A: MADS box transcription enhancer factor 2 polypeptide A (myocyte enhancer factor 2A) www.broad.mit.e...
Broad V$OCT1_Q5_01 View Gene Set 2.282e-05 209 0.001559 9 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TNATTTGCATW which matches annotation for POU2F1: POU domain class 2 transcription factor 1 www.broad.mit.e...
Broad V$MEF2_02 View Gene Set 3.837e-05 182 0.002219 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNNNNNKCTAWAAATAGMNNNN. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MEF2_03 View Gene Set 4.244e-05 184 0.002219 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNNNNWKCTAWAAATAGMNNNN. Motif does not match any known transcription factor www.broad.mit.e...
Broad TAATTA_V$CHX10_01 View Gene Set 4.329e-05 612 0.002219 10 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TAATTA which matches annotation for VSX1: visual system homeobox 1 homolog CHX10-like (zebrafish) www.broad.mit.e...
Broad V$OCT1_Q6 View Gene Set 5.883e-05 202 0.002618 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNATGCAAATNAN which matches annotation for POU2F1: POU domain class 2 transcription factor 1 www.broad.mit.e...
Broad V$CHX10_01 View Gene Set 6.144e-05 182 0.002618 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNTAATTAGCNNN which matches annotation for VSX1: visual system homeobox 1 homolog CHX10-like (zebrafish) www.broad.mit.e...
Broad V$OCT_Q6 View Gene Set 6.386e-05 206 0.002618 13 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TNATTTGCATN. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$GATA_C View Gene Set 7.707e-05 204 0.002962 16 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NGATAAGNMNN which matches annotation for GATA1: GATA binding protein 1 (globin transcription factor 1) www.broad.mit.e...
Broad TGATTTRY_V$GFI1_01 View Gene Set 9.255e-05 234 0.003223 17 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TGATTTRY which matches annotation for GFI1: growth factor independent 1 www.broad.mit.e...
Broad YATGNWAAT_V$OCT_C View Gene Set 9.433e-05 289 0.003223 17 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif YATGNWAAT. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$NKX3A_01 View Gene Set 0.0001307 166 0.004231 19 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NWATAAGTATWT which matches annotation for NKX3-1: NK3 transcription factor related locus 1 (Drosophila) www.broad.mit.e...
Broad V$GATA1_04 View Gene Set 0.0001953 191 0.006004 20 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNCWGATARNNNN which matches annotation for GATA1: GATA binding protein 1 (globin transcription factor 1) www.broad.mit.e...
Broad V$TAL1BETAE47_01 View Gene Set 0.0002276 184 0.006356 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNAACAGATGKTNNN which matches annotation for TAL1: T-cell acute lymphocytic leukemia 1<br> TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) www.broad.mit.e...
Broad V$TAL1BETAITF2_01 View Gene Set 0.0002397 191 0.006356 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNAACAGATGKTNNN which matches annotation for TAL1: T-cell acute lymphocytic leukemia 1<br> TCF4: transcription factor 4 www.broad.mit.e...
Broad V$OCT1_05 View Gene Set 0.0002584 201 0.006356 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif MKVATTTGCATATT which matches annotation for POU2F1: POU domain class 2 transcription factor 1 www.broad.mit.e...
Broad V$OCT1_B View Gene Set 0.0002545 213 0.006356 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TATGCAAATN which matches annotation for POU2F1: POU domain class 2 transcription factor 1 www.broad.mit.e...
Broad V$HMEF2_Q6 View Gene Set 0.0002258 108 0.006356 21 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif SKYTAAAAATAACYCH. Motif does not match any known transcription factor www.broad.mit.e...
Broad CAGGTG_V$E12_Q6 View Gene Set 0.000274 1818 0.006482 26 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CAGGTG which matches annotation for TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) www.broad.mit.e...
Broad TAAYNRNNTCC_UNKNOWN View Gene Set 0.0003173 129 0.007227 27 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TAAYNRNNTCC. Motif does not match any known transcription factor www.broad.mit.e...
Broad CAGCTG_V$AP4_Q5 View Gene Set 0.0003816 1129 0.008382 28 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CAGCTG which matches annotation for REPIN1: replication initiator 1 www.broad.mit.e...
Broad YATTNATC_UNKNOWN View Gene Set 0.0004289 275 0.009029 29 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif YATTNATC. Motif does not match any known transcription factor www.broad.mit.e...
Broad GGATTA_V$PITX2_Q2 View Gene Set 0.0004405 456 0.009029 29 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGATTA which matches annotation for PITX2: paired-like homeodomain transcription factor 2 www.broad.mit.e...
Broad V$NKX61_01 View Gene Set 0.0004631 177 0.009188 31 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TWTTTAATTGGTT which matches annotation for NKX6-1: NK6 transcription factor related locus 1 (Drosophila) www.broad.mit.e...
Broad V$MEF2_Q6_01 View Gene Set 0.0004823 191 0.00927 32 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif RGCTATWTTTAR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MMEF2_Q6 View Gene Set 0.0005552 215 0.01035 33 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CKSNYTAAAAAWRMCY. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$PBX1_02 View Gene Set 0.0007207 107 0.01266 34 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNCATCAATCAANNW which matches annotation for PBX1: pre-B-cell leukemia transcription factor 1 www.broad.mit.e...
Broad GATAAGR_V$GATA_C View Gene Set 0.0007158 232 0.01266 34 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GATAAGR. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$NKX25_02 View Gene Set 0.0007891 199 0.01323 36 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CWTAATTG which matches annotation for NKX2-5: NK2 transcription factor related locus 5 (Drosophila) www.broad.mit.e...
Broad V$FREAC4_01 View Gene Set 0.0007961 111 0.01323 36 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CTWAWGTAAACANWGN which matches annotation for FOXD1: forkhead box D1 www.broad.mit.e...
Broad RAAGNYNNCTTY_UNKNOWN View Gene Set 0.0008588 110 0.01379 38 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif RAAGNYNNCTTY. Motif does not match any known transcription factor www.broad.mit.e...
Broad GCANCTGNY_V$MYOD_Q6 View Gene Set 0.0008748 673 0.01379 38 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCANCTGNY which matches annotation for MYOD1: myogenic differentiation 1 www.broad.mit.e...
Broad V$OCT_C View Gene Set 0.0009464 206 0.0142 40 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CTNATTTGCATAY. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$GATA6_01 View Gene Set 0.0009306 191 0.0142 40 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNGATWANN which matches annotation for GATA6: GATA binding protein 6 www.broad.mit.e...
Broad V$HNF1_Q6 View Gene Set 0.0009704 195 0.01421 42 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif WRGTTAATNATTAACNNN which matches annotation for TCF1: transcription factor 1 hepatic; LF-B1 hepatic nuclear factor (HNF1) albumin proximal factor www.broad.mit.e...
Broad GTGGGTGK_UNKNOWN View Gene Set 0.001055 224 0.01508 43 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GTGGGTGK. Motif does not match any known transcription factor www.broad.mit.e...
Broad YTAATTAA_V$LHX3_01 View Gene Set 0.001104 144 0.01544 44 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif YTAATTAA which matches annotation for LHX3: LIM homeobox 3 www.broad.mit.e...
Broad V$TAL1ALPHAE47_01 View Gene Set 0.001181 192 0.01579 45 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNAACAGATGKTNNN which matches annotation for TAL1: T-cell acute lymphocytic leukemia 1<br> TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) www.broad.mit.e...
Broad CAGNWMCNNNGAC_UNKNOWN View Gene Set 0.001166 68 0.01579 45 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CAGNWMCNNNGAC. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$S8_01 View Gene Set 0.001238 195 0.0162 47 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif WNNANYYAATTANCNN which matches annotation for PRRX2: paired related homeobox 2 www.broad.mit.e...
Broad V$TATA_01 View Gene Set 0.001511 218 0.01896 48 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif STATAAAWRNNNNNN which matches annotation for TAF<br> TATA www.broad.mit.e...
Broad V$E2A_Q2 View Gene Set 0.001482 179 0.01896 48 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCACCTGYYNCNKN which matches annotation for TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) www.broad.mit.e...
Broad V$AFP1_Q6 View Gene Set 0.001608 198 0.01965 50 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif ATTAAYTRCAC which matches annotation for ZHX2: zinc fingers and homeoboxes 2 www.broad.mit.e...
Broad YNTTTNNNANGCARM_UNKNOWN View Gene Set 0.00163 55 0.01965 50 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif YNTTTNNNANGCARM. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$MYOD_Q6_01 View Gene Set 0.001714 182 0.02027 52 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CNGNRNCAGGTGNNGNAN which matches annotation for MYOD1: myogenic differentiation 1 www.broad.mit.e...
Broad V$AP4_Q6_01 View Gene Set 0.002563 191 0.02975 53 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RNCAGCTGC which matches annotation for TFAP4: transcription factor AP-4 (activating enhancer binding protein 4) www.broad.mit.e...
Broad V$RSRFC4_Q2 View Gene Set 0.003004 168 0.03421 54 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif ANKCTAWAAATAGMHNN which matches annotation for MEF2A: MADS box transcription enhancer factor 2 polypeptide A (myocyte enhancer factor 2A) www.broad.mit.e...
Broad YCATTAA_UNKNOWN View Gene Set 0.00315 426 0.03459 55 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif YCATTAA. Motif does not match any known transcription factor www.broad.mit.e...
Broad TGCCAAR_V$NF1_Q6 View Gene Set 0.003097 532 0.03459 55 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TGCCAAR which matches annotation for NF1: neurofibromin 1 (neurofibromatosis von Recklinghausen disease Watson disease) www.broad.mit.e...
Broad V$TBP_01 View Gene Set 0.003293 189 0.03553 57 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TATAAATW which matches annotation for TBP: TATA box binding protein www.broad.mit.e...
Broad V$AMEF2_Q6 View Gene Set 0.003526 194 0.03738 58 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CKGDYTAAAAATAACYMM. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$HNF1_C View Gene Set 0.003684 174 0.0384 59 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif DGTTAATKAWTNACCAM which matches annotation for TCF1: transcription factor 1 hepatic; LF-B1 hepatic nuclear factor (HNF1) albumin proximal factor www.broad.mit.e...
Broad CAGGTA_V$AREB6_01 View Gene Set 0.003962 575 0.04061 60 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CAGGTA which matches annotation for TCF8: transcription factor 8 (represses interleukin 2 expression) www.broad.mit.e...
Broad V$NKX62_Q2 View Gene Set 0.004101 187 0.04135 61 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NWADTAAWTANN which matches annotation for NKX6-2: NK6 transcription factor related locus 2 (Drosophila) www.broad.mit.e...
Broad V$MEF2_01 View Gene Set 0.004475 117 0.04437 62 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CTCTAAAAATAACYCY. Motif does not match any known transcription factor www.broad.mit.e...
Broad V$HNF1_01 View Gene Set 0.004545 183 0.04437 62 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGTTAATNWTTAMCN which matches annotation for TCF1: transcription factor 1 hepatic; LF-B1 hepatic nuclear factor (HNF1) albumin proximal factor www.broad.mit.e...
Broad V$CRX_Q4 View Gene Set 0.004938 207 0.04683 64 Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif YNNNTAATCYCMN which matches annotation for CRX: cone-rod homeobox www.broad.mit.e...
Broad TGACATY_UNKNOWN View Gene Set 0.00495 503 0.04683 64 Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TGACATY. Motif does not match any known transcription factor www.broad.mit.e...

Gene Set Collection: Broad.c4.CGN

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad MORF_ARL3 View Gene Set 4.289e-08 291 1.831e-05 1 Neighborhood of ARL3 www.broad.mit.e...
Broad MORF_MAGEA9 View Gene Set 8.735e-08 405 1.865e-05 2 Neighborhood of MAGEA9 www.broad.mit.e...
Broad MORF_FOSL1 View Gene Set 2.171e-07 386 2.318e-05 3 Neighborhood of FOSL1 www.broad.mit.e...
Broad MORF_NOS2A View Gene Set 1.708e-07 276 2.318e-05 3 Neighborhood of NOS2A www.broad.mit.e...
Broad MORF_ERCC4 View Gene Set 3.054e-07 309 2.608e-05 5 Neighborhood of ERCC4 www.broad.mit.e...
Broad MORF_RAD51L3 View Gene Set 1.771e-06 371 0.000126 6 Neighborhood of RAD51L3 www.broad.mit.e...
Broad MORF_CD8A View Gene Set 2.323e-06 121 0.0001417 7 Neighborhood of CD8A www.broad.mit.e...
Broad GNF2_HPX View Gene Set 2.83e-06 134 0.000151 8 Neighborhood of HPX www.broad.mit.e...
Broad MORF_PAX7 View Gene Set 6.443e-06 251 0.0003057 9 Neighborhood of PAX7 www.broad.mit.e...
Broad GNF2_LCAT View Gene Set 1.046e-05 123 0.0004465 10 Neighborhood of LCAT www.broad.mit.e...
Broad GNF2_GSTM1 View Gene Set 1.199e-05 108 0.0004656 11 Neighborhood of GSTM1 www.broad.mit.e...
Broad GNF2_TST View Gene Set 1.686e-05 103 0.0005998 12 Neighborhood of TST www.broad.mit.e...
Broad MORF_MAP3K14 View Gene Set 2.013e-05 110 0.0006383 13 Neighborhood of MAP3K14 www.broad.mit.e...
Broad GNF2_HPN View Gene Set 2.14e-05 132 0.0006383 13 Neighborhood of HPN www.broad.mit.e...
Broad GNF2_TM4SF2 View Gene Set 2.242e-05 23 0.0006383 13 Neighborhood of TM4SF2 www.broad.mit.e...
Broad MORF_SUPT3H View Gene Set 2.583e-05 318 0.0006894 16 Neighborhood of SUPT3H www.broad.mit.e...
Broad MORF_NF1 View Gene Set 2.961e-05 158 0.0007024 17 Neighborhood of NF1 www.broad.mit.e...
Broad MORF_ETV3 View Gene Set 2.92e-05 63 0.0007024 17 Neighborhood of ETV3 www.broad.mit.e...
Broad GNF2_CYP2B6 View Gene Set 3.747e-05 49 0.0008421 19 Neighborhood of CYP2B6 www.broad.mit.e...
Broad MORF_MAGEA8 View Gene Set 4.124e-05 250 0.0008805 20 Neighborhood of MAGEA8 www.broad.mit.e...
Broad MORF_FSHR View Gene Set 4.61e-05 268 0.0008949 21 Neighborhood of FSHR www.broad.mit.e...
Broad MORF_MAP2K7 View Gene Set 4.479e-05 179 0.0008949 21 Neighborhood of MAP2K7 www.broad.mit.e...
Broad MORF_CAMK4 View Gene Set 5.193e-05 281 0.0009641 23 Neighborhood of CAMK4 www.broad.mit.e...
Broad GNF2_CEBPA View Gene Set 5.874e-05 64 0.001045 24 Neighborhood of CEBPA www.broad.mit.e...
Broad GNF2_TIMP2 View Gene Set 6.418e-05 45 0.001096 25 Neighborhood of TIMP2 www.broad.mit.e...
Broad MORF_IFNA1 View Gene Set 6.94e-05 198 0.00114 26 Neighborhood of IFNA1 www.broad.mit.e...
Broad MORF_ATF2 View Gene Set 7.381e-05 318 0.001167 27 Neighborhood of ATF2 www.broad.mit.e...
Broad GNF2_KISS1 View Gene Set 7.875e-05 48 0.001201 28 Neighborhood of KISS1 www.broad.mit.e...
Broad MORF_BCL2 View Gene Set 0.0001023 202 0.001456 29 Neighborhood of BCL2 www.broad.mit.e...
Broad GNF2_CCNA1 View Gene Set 9.925e-05 59 0.001456 29 Neighborhood of CCNA1 www.broad.mit.e...
Broad MORF_LCAT View Gene Set 0.0001188 124 0.001636 31 Neighborhood of LCAT www.broad.mit.e...
Broad GNF2_MMP11 View Gene Set 0.0001472 41 0.001964 32 Neighborhood of MMP11 www.broad.mit.e...
Broad MORF_PRKCA View Gene Set 0.0001638 174 0.002004 33 Neighborhood of PRKCA www.broad.mit.e...
Broad MORF_TNFRSF25 View Gene Set 0.0001642 242 0.002004 33 Neighborhood of TNFRSF25 www.broad.mit.e...
Broad GNF2_DNM1 View Gene Set 0.0001571 69 0.002004 33 Neighborhood of DNM1 www.broad.mit.e...
Broad MORF_BCL2L11 View Gene Set 0.0001853 178 0.002185 36 Neighborhood of BCL2L11 www.broad.mit.e...
Broad MORF_MYL3 View Gene Set 0.0001996 69 0.002185 36 Neighborhood of MYL3 www.broad.mit.e...
Broad MORF_WNT1 View Gene Set 0.0001958 99 0.002185 36 Neighborhood of WNT1 www.broad.mit.e...
Broad GNF2_IGF1 View Gene Set 0.000194 26 0.002185 36 Neighborhood of IGF1 www.broad.mit.e...
Broad MORF_FLT1 View Gene Set 0.0002141 117 0.002285 40 Neighborhood of FLT1 www.broad.mit.e...
Broad GNF2_MLF1 View Gene Set 0.000227 76 0.002364 41 Neighborhood of MLF1 www.broad.mit.e...
Broad GNF2_CD33 View Gene Set 0.0002372 46 0.002411 42 Neighborhood of CD33 www.broad.mit.e...
Broad MORF_MDM2 View Gene Set 0.0003038 269 0.003016 43 Neighborhood of MDM2 www.broad.mit.e...
Broad MORF_CDH4 View Gene Set 0.0003446 134 0.003339 44 Neighborhood of CDH4 www.broad.mit.e...
Broad GNF2_IL2RB View Gene Set 0.0003519 44 0.003339 44 Neighborhood of IL2RB www.broad.mit.e...
Broad MORF_KDR View Gene Set 0.0003915 90 0.003634 46 Neighborhood of KDR www.broad.mit.e...
Broad MORF_TFDP2 View Gene Set 0.0004066 215 0.003694 47 Neighborhood of TFDP2 www.broad.mit.e...
Broad GNF2_MAPT View Gene Set 0.0004544 38 0.004042 48 Neighborhood of MAPT www.broad.mit.e...
Broad MORF_EPHA7 View Gene Set 0.0005187 128 0.004303 49 Neighborhood of EPHA7 www.broad.mit.e...
Broad MORF_IL4 View Gene Set 0.0005182 186 0.004303 49 Neighborhood of IL4 www.broad.mit.e...
Broad GNF2_CDH3 View Gene Set 0.000524 24 0.004303 49 Neighborhood of CDH3 www.broad.mit.e...
Broad GNF2_IGFBP1 View Gene Set 0.0005159 35 0.004303 49 Neighborhood of IGFBP1 www.broad.mit.e...
Broad MORF_CTSB View Gene Set 0.0005365 182 0.004323 53 Neighborhood of CTSB www.broad.mit.e...
Broad MORF_MLLT10 View Gene Set 0.0005504 290 0.004352 54 Neighborhood of MLLT10 www.broad.mit.e...
Broad CAR_HPX View Gene Set 0.000605 73 0.004613 55 Neighborhood of HPX www.broad.mit.e...
Broad GNF2_CD97 View Gene Set 0.0006042 37 0.004613 55 Neighborhood of CD97 www.broad.mit.e...
Broad MORF_RAB3A View Gene Set 0.0006201 85 0.004645 57 Neighborhood of RAB3A www.broad.mit.e...
Broad MORF_IL13 View Gene Set 0.0007862 216 0.005736 58 Neighborhood of IL13 www.broad.mit.e...
Broad MORF_PTPRB View Gene Set 0.0007925 241 0.005736 58 Neighborhood of PTPRB www.broad.mit.e...
Broad GNF2_S100A4 View Gene Set 0.001092 43 0.007774 60 Neighborhood of S100A4 www.broad.mit.e...
Broad CAR_IGFBP1 View Gene Set 0.001242 57 0.008694 61 Neighborhood of IGFBP1 www.broad.mit.e...
Broad GNF2_RAB3A View Gene Set 0.001303 34 0.008974 62 Neighborhood of RAB3A www.broad.mit.e...
Broad GNF2_CARD15 View Gene Set 0.001333 62 0.009034 63 Neighborhood of CARD15 www.broad.mit.e...
Broad GCM_PTPRU View Gene Set 0.001425 55 0.009511 64 Neighborhood of PTPRU www.broad.mit.e...
Broad MORF_JAG1 View Gene Set 0.001661 87 0.01091 65 Neighborhood of JAG1 www.broad.mit.e...
Broad MORF_TNFRSF6 View Gene Set 0.002009 159 0.013 66 Neighborhood of TNFRSF6 www.broad.mit.e...
Broad MORF_FRK View Gene Set 0.002078 102 0.01324 67 Neighborhood of FRK www.broad.mit.e...
Broad MORF_IL16 View Gene Set 0.002207 227 0.01351 68 Neighborhood of IL16 www.broad.mit.e...
Broad MORF_IL9 View Gene Set 0.002214 85 0.01351 68 Neighborhood of IL9 www.broad.mit.e...
Broad GNF2_CD7 View Gene Set 0.002206 38 0.01351 68 Neighborhood of CD7 www.broad.mit.e...
Broad MORF_STK17A View Gene Set 0.002388 155 0.01436 71 Neighborhood of STK17A www.broad.mit.e...
Broad MORF_PPP2R5B View Gene Set 0.002458 162 0.01458 72 Neighborhood of PPP2R5B www.broad.mit.e...
Broad CAR_MLANA View Gene Set 0.002673 42 0.01563 73 Neighborhood of MLANA www.broad.mit.e...
Broad MORF_THRA View Gene Set 0.003203 50 0.01848 74 Neighborhood of THRA www.broad.mit.e...
Broad GNF2_PTX3 View Gene Set 0.003248 36 0.01849 75 Neighborhood of PTX3 www.broad.mit.e...
Broad MORF_PTPRR View Gene Set 0.00353 98 0.01983 76 Neighborhood of PTPRR www.broad.mit.e...
Broad MORF_THPO View Gene Set 0.003627 123 0.02011 77 Neighborhood of THPO www.broad.mit.e...
Broad GNF2_MYL2 View Gene Set 0.004053 32 0.022 78 Neighborhood of MYL2 www.broad.mit.e...
Broad GNF2_SERPINB5 View Gene Set 0.004071 25 0.022 78 Neighborhood of SERPINB5 www.broad.mit.e...
Broad GNF2_CD1D View Gene Set 0.004374 41 0.02306 80 Neighborhood of CD1D www.broad.mit.e...
Broad GNF2_RTN1 View Gene Set 0.00436 45 0.02306 80 Neighborhood of RTN1 www.broad.mit.e...
Broad GNF2_PTPN4 View Gene Set 0.005384 47 0.02804 82 Neighborhood of PTPN4 www.broad.mit.e...
Broad GCM_CDH5 View Gene Set 0.006831 35 0.03514 83 Neighborhood of CDH5 www.broad.mit.e...
Broad GNF2_CDKN1C View Gene Set 0.007124 27 0.03621 84 Neighborhood of CDKN1C www.broad.mit.e...
Broad MORF_ITGA2 View Gene Set 0.008214 53 0.04126 85 Neighborhood of ITGA2 www.broad.mit.e...
Broad GCM_HMGA2 View Gene Set 0.008405 123 0.04173 86 Neighborhood of HMGA2 www.broad.mit.e...
Broad GNF2_ITGAL View Gene Set 0.008504 49 0.04174 87 Neighborhood of ITGAL www.broad.mit.e...
Broad GNF2_MATK View Gene Set 0.008859 23 0.04299 88 Neighborhood of MATK www.broad.mit.e...
Broad GNF2_MMP1 View Gene Set 0.009235 32 0.04431 89 Neighborhood of MMP1 www.broad.mit.e...
Broad GNF2_SPINK1 View Gene Set 0.009612 24 0.04561 90 Neighborhood of SPINK1 www.broad.mit.e...

Gene Set Collection: Broad.c4.CM

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad module_64 View Gene Set 1.388e-25 506 6.302e-23 1 Genes in module_64 www.broad.mit.e...
Broad module_117 View Gene Set 4.26e-24 699 9.671e-22 2 Genes in module_117 www.broad.mit.e...
Broad module_84 View Gene Set 1.981e-20 526 2.998e-18 3 Genes in module_84 www.broad.mit.e...
Broad module_75 View Gene Set 2.849e-17 391 3.233e-15 4 Genes in module_75 www.broad.mit.e...
Broad module_220 View Gene Set 1.202e-16 328 1.092e-14 5 Genes in module_220 www.broad.mit.e...
Broad module_46 View Gene Set 3.444e-16 386 2.606e-14 6 Genes in module_46 www.broad.mit.e...
Broad module_55 View Gene Set 6.578e-15 807 3.893e-13 7 Genes in module_55 www.broad.mit.e...
Broad module_66 View Gene Set 6.86e-15 530 3.893e-13 7 Genes in module_66 www.broad.mit.e...
Broad module_100 View Gene Set 9.386e-15 523 4.735e-13 9 Genes in module_100 www.broad.mit.e...
Broad module_88 View Gene Set 3.276e-14 812 1.487e-12 10 Genes in module_88 www.broad.mit.e...
Broad module_137 View Gene Set 3.726e-14 525 1.538e-12 11 Genes in module_137 www.broad.mit.e...
Broad module_27 View Gene Set 4.765e-13 345 1.803e-11 12 Genes in module_27 www.broad.mit.e...
Broad module_41 View Gene Set 5.588e-13 542 1.952e-11 13 Genes in module_41 www.broad.mit.e...
Broad module_45 View Gene Set 2.478e-12 563 8.036e-11 14 Genes in module_45 www.broad.mit.e...
Broad module_99 View Gene Set 1.165e-10 346 3.525e-09 15 Genes in module_99 www.broad.mit.e...
Broad module_47 View Gene Set 1.684e-10 216 4.779e-09 16 Genes in module_47 www.broad.mit.e...
Broad module_104 View Gene Set 2.079e-10 337 5.552e-09 17 Genes in module_104 www.broad.mit.e...
Broad module_63 View Gene Set 2.863e-10 210 7.222e-09 18 Genes in module_63 www.broad.mit.e...
Broad module_11 View Gene Set 3.13e-10 520 7.479e-09 19 Genes in module_11 www.broad.mit.e...
Broad module_112 View Gene Set 3.929e-09 255 8.918e-08 20 Genes in module_112 www.broad.mit.e...
Broad module_12 View Gene Set 6.356e-09 346 1.374e-07 21 Genes in module_12 www.broad.mit.e...
Broad module_176 View Gene Set 1.231e-08 225 2.506e-07 22 Genes in module_176 www.broad.mit.e...
Broad module_181 View Gene Set 1.27e-08 292 2.506e-07 22 Genes in module_181 www.broad.mit.e...
Broad module_92 View Gene Set 4.783e-08 146 9.048e-07 24 Genes in module_92 www.broad.mit.e...
Broad module_1 View Gene Set 1.664e-07 355 3.022e-06 25 Genes in module_1 www.broad.mit.e...
Broad module_5 View Gene Set 2.183e-07 420 3.812e-06 26 Genes in module_5 www.broad.mit.e...
Broad module_263 View Gene Set 6.702e-07 43 1.127e-05 27 Genes in module_263 www.broad.mit.e...
Broad module_108 View Gene Set 1.164e-06 52 1.888e-05 28 Genes in module_108 www.broad.mit.e...
Broad module_122 View Gene Set 1.614e-06 138 2.526e-05 29 Genes in module_122 www.broad.mit.e...
Broad module_113 View Gene Set 2.262e-06 105 3.424e-05 30 Genes in module_113 www.broad.mit.e...
Broad module_242 View Gene Set 2.777e-06 204 4.067e-05 31 Genes in module_242 www.broad.mit.e...
Broad module_23 View Gene Set 3.722e-06 552 5.28e-05 32 Genes in module_23 www.broad.mit.e...
Broad module_2 View Gene Set 4.233e-06 373 5.824e-05 33 Genes in module_2 www.broad.mit.e...
Broad module_289 View Gene Set 5.282e-06 118 7.053e-05 34 Genes in module_289 www.broad.mit.e...
Broad module_33 View Gene Set 7.502e-06 369 9.731e-05 35 Genes in module_33 www.broad.mit.e...
Broad module_38 View Gene Set 1.079e-05 453 0.0001361 36 Genes in module_38 www.broad.mit.e...
Broad module_379 View Gene Set 1.498e-05 194 0.0001839 37 Genes in module_379 www.broad.mit.e...
Broad module_24 View Gene Set 2.514e-05 443 0.0003004 38 Genes in module_24 www.broad.mit.e...
Broad module_213 View Gene Set 3.7e-05 77 0.0004098 39 Genes in module_213 www.broad.mit.e...
Broad module_234 View Gene Set 3.57e-05 53 0.0004098 39 Genes in module_234 www.broad.mit.e...
Broad module_433 View Gene Set 3.64e-05 60 0.0004098 39 Genes in module_433 www.broad.mit.e...
Broad module_199 View Gene Set 4.346e-05 57 0.0004698 42 Genes in module_199 www.broad.mit.e...
Broad module_259 View Gene Set 4.501e-05 46 0.0004753 43 Genes in module_259 www.broad.mit.e...
Broad module_44 View Gene Set 5.653e-05 319 0.0005833 44 Genes in module_44 www.broad.mit.e...
Broad module_121 View Gene Set 8.776e-05 98 0.0008854 45 Genes in module_121 www.broad.mit.e...
Broad module_274 View Gene Set 9.417e-05 82 0.0009294 46 Genes in module_274 www.broad.mit.e...
Broad module_76 View Gene Set 0.0001005 79 0.0009503 47 Genes in module_76 www.broad.mit.e...
Broad module_146 View Gene Set 9.895e-05 92 0.0009503 47 Genes in module_146 www.broad.mit.e...
Broad module_130 View Gene Set 0.0001279 23 0.001183 49 Genes in module_130 www.broad.mit.e...
Broad module_489 View Gene Set 0.0001303 30 0.001183 49 Genes in module_489 www.broad.mit.e...
Broad module_94 View Gene Set 0.0001638 362 0.001458 51 Genes in module_94 www.broad.mit.e...
Broad module_129 View Gene Set 0.0001972 215 0.001701 52 Genes in module_129 www.broad.mit.e...
Broad module_208 View Gene Set 0.0001986 118 0.001701 52 Genes in module_208 www.broad.mit.e...
Broad module_85 View Gene Set 0.0002323 51 0.001953 54 Genes in module_85 www.broad.mit.e...
Broad module_329 View Gene Set 0.0002387 51 0.00197 55 Genes in module_329 www.broad.mit.e...
Broad module_223 View Gene Set 0.0002573 140 0.002086 56 Genes in module_223 www.broad.mit.e...
Broad module_316 View Gene Set 0.0002676 70 0.002131 57 Genes in module_316 www.broad.mit.e...
Broad module_6 View Gene Set 0.0002946 403 0.002306 58 Genes in module_6 www.broad.mit.e...
Broad module_297 View Gene Set 0.0003091 78 0.002339 59 Genes in module_297 www.broad.mit.e...
Broad module_375 View Gene Set 0.0003073 84 0.002339 59 Genes in module_375 www.broad.mit.e...
Broad module_111 View Gene Set 0.0003256 151 0.002424 61 Genes in module_111 www.broad.mit.e...
Broad module_58 View Gene Set 0.0003462 21 0.002535 62 Genes in module_58 www.broad.mit.e...
Broad module_171 View Gene Set 0.0003564 131 0.002568 63 Genes in module_171 www.broad.mit.e...
Broad module_287 View Gene Set 0.0004111 49 0.002917 64 Genes in module_287 www.broad.mit.e...
Broad module_131 View Gene Set 0.0004284 33 0.002992 65 Genes in module_131 www.broad.mit.e...
Broad module_154 View Gene Set 0.0004493 73 0.003091 66 Genes in module_154 www.broad.mit.e...
Broad module_96 View Gene Set 0.0005005 36 0.003391 67 Genes in module_96 www.broad.mit.e...
Broad module_387 View Gene Set 0.0005238 49 0.003497 68 Genes in module_387 www.broad.mit.e...
Broad module_357 View Gene Set 0.0005952 78 0.003916 69 Genes in module_357 www.broad.mit.e...
Broad module_400 View Gene Set 0.000606 19 0.00393 70 Genes in module_400 www.broad.mit.e...
Broad module_292 View Gene Set 0.0006255 129 0.004 71 Genes in module_292 www.broad.mit.e...
Broad module_324 View Gene Set 0.0007684 131 0.004845 72 Genes in module_324 www.broad.mit.e...
Broad module_7 View Gene Set 0.0007876 227 0.004898 73 Genes in module_7 www.broad.mit.e...
Broad module_13 View Gene Set 0.0008233 498 0.005051 74 Genes in module_13 www.broad.mit.e...
Broad module_157 View Gene Set 0.0009176 105 0.005555 75 Genes in module_157 www.broad.mit.e...
Broad module_367 View Gene Set 0.00111 27 0.006633 76 Genes in module_367 www.broad.mit.e...
Broad module_248 View Gene Set 0.001303 126 0.007685 77 Genes in module_248 www.broad.mit.e...
Broad module_436 View Gene Set 0.001364 129 0.007937 78 Genes in module_436 www.broad.mit.e...
Broad module_134 View Gene Set 0.002215 28 0.01241 79 Genes in module_134 www.broad.mit.e...
Broad module_201 View Gene Set 0.00221 50 0.01241 79 Genes in module_201 www.broad.mit.e...
Broad module_410 View Gene Set 0.002176 35 0.01241 79 Genes in module_410 www.broad.mit.e...
Broad module_109 View Gene Set 0.002392 34 0.01324 82 Genes in module_109 www.broad.mit.e...
Broad module_60 View Gene Set 0.002906 403 0.0159 83 Genes in module_60 www.broad.mit.e...
Broad module_382 View Gene Set 0.003095 28 0.01673 84 Genes in module_382 www.broad.mit.e...
Broad module_119 View Gene Set 0.003526 135 0.01883 85 Genes in module_119 www.broad.mit.e...
Broad module_345 View Gene Set 0.004738 118 0.02501 86 Genes in module_345 www.broad.mit.e...
Broad module_165 View Gene Set 0.005656 78 0.02952 87 Genes in module_165 www.broad.mit.e...
Broad module_107 View Gene Set 0.006392 77 0.03298 88 Genes in module_107 www.broad.mit.e...
Broad module_330 View Gene Set 0.00816 28 0.04162 89 Genes in module_330 www.broad.mit.e...
Broad module_458 View Gene Set 0.008718 35 0.04398 90 Genes in module_458 www.broad.mit.e...
Broad module_545 View Gene Set 0.009181 19 0.0458 91 Genes in module_545 www.broad.mit.e...
Broad module_497 View Gene Set 0.009535 29 0.04706 92 Genes in module_497 www.broad.mit.e...
Broad module_205 View Gene Set 0.009738 259 0.04754 93 Genes in module_205 www.broad.mit.e...
Broad module_444 View Gene Set 0.009882 18 0.04773 94 Genes in module_444 www.broad.mit.e...
Broad module_209 View Gene Set 0.01028 86 0.04911 95 Genes in module_209 www.broad.mit.e...

Gene Set Collection: Broad.c5.BP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad CELL_CELL_SIGNALING View Gene Set 6.588e-13 400 3.028e-10 1 Genes annotated by the GO term GO:0007267. Any process that mediates the transfer of information from one cell to another. www.broad.mit.e...
Broad ANATOMICAL_STRUCTURE_DEVELOPMENT View Gene Set 7.341e-13 1004 3.028e-10 1 Genes annotated by the GO term GO:0048856. The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel or microscopic such as an acrosome. www.broad.mit.e...
Broad SYSTEM_PROCESS View Gene Set 2.432e-12 558 6.688e-10 3 Genes annotated by the GO term GO:0003008. A biological process occurring at the level of an organ system pertinent to the function of the organism. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. www.broad.mit.e...
Broad SYSTEM_DEVELOPMENT View Gene Set 6.71e-12 853 1.107e-09 4 Genes annotated by the GO term GO:0048731. The process whose specific outcome is the progression of an organismal system over time from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. www.broad.mit.e...
Broad MULTICELLULAR_ORGANISMAL_DEVELOPMENT View Gene Set 5.995e-12 1037 1.107e-09 4 Genes annotated by the GO term GO:0007275. The biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). www.broad.mit.e...
Broad G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY View Gene Set 3.22e-11 326 4.428e-09 6 Genes annotated by the GO term GO:0007186. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand. www.broad.mit.e...
Broad CELL_SURFACE_RECEPTOR_LINKED_SIGNAL_TRANSDUCTION_GO_0007166 View Gene Set 6.663e-11 620 7.853e-09 7 Genes annotated by the GO term GO:0007166. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell. www.broad.mit.e...
Broad RESPONSE_TO_EXTERNAL_STIMULUS View Gene Set 5.282e-10 305 5.447e-08 8 Genes annotated by the GO term GO:0009605. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of an external stimulus. www.broad.mit.e...
Broad NEUROLOGICAL_SYSTEM_PROCESS View Gene Set 3.562e-09 377 3.265e-07 9 Genes annotated by the GO term GO:0050877. The processes pertaining to the functions of the nervous system of an organism. www.broad.mit.e...
Broad RESPONSE_TO_WOUNDING View Gene Set 3.585e-08 184 2.958e-06 10 Genes annotated by the GO term GO:0009611. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus indicating damage to the organism. www.broad.mit.e...
Broad BEHAVIOR View Gene Set 4.083e-08 148 3.062e-06 11 Genes annotated by the GO term GO:0007610. The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. www.broad.mit.e...
Broad DEFENSE_RESPONSE View Gene Set 6.502e-08 264 4.47e-06 12 Genes annotated by the GO term GO:0006952. Reactions triggered in response to the presence of a foreign body or the occurrence of an injury which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. www.broad.mit.e...
Broad SYNAPTIC_TRANSMISSION View Gene Set 1.907e-07 172 1.21e-05 13 Genes annotated by the GO term GO:0007268. The process of communication from a neuron to a target (neuron muscle or secretory cell) across a synapse. www.broad.mit.e...
Broad NERVOUS_SYSTEM_DEVELOPMENT View Gene Set 6.357e-07 380 3.746e-05 14 Genes annotated by the GO term GO:0007399. The process whose specific outcome is the progression of nervous tissue over time from its formation to its mature state. www.broad.mit.e...
Broad ORGAN_DEVELOPMENT View Gene Set 1.081e-06 567 5.943e-05 15 Genes annotated by the GO term GO:0048513. Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time from its formation to the mature structure. Organs are commonly observed as visibly distinct structures but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. www.broad.mit.e...
Broad REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS View Gene Set 1.68e-06 149 8.665e-05 16 Genes annotated by the GO term GO:0051239. Any process that modulates the frequency rate or extent of an organismal process the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. www.broad.mit.e...
Broad IMMUNE_SYSTEM_PROCESS View Gene Set 2.692e-06 326 0.0001307 17 Genes annotated by the GO term GO:0002376. Any process involved in the development or functioning of the immune system an organismal system for calibrated responses to potential internal or invasive threats. www.broad.mit.e...
Broad INFLAMMATORY_RESPONSE View Gene Set 4.209e-06 124 0.0001929 18 Genes annotated by the GO term GO:0006954. The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. www.broad.mit.e...
Broad TRANSMISSION_OF_NERVE_IMPULSE View Gene Set 6.174e-06 187 0.0002681 19 Genes annotated by the GO term GO:0019226. The sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation. www.broad.mit.e...
Broad LOCOMOTORY_BEHAVIOR View Gene Set 7.363e-06 91 0.0003037 20 Genes annotated by the GO term GO:0007626. The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. www.broad.mit.e...
Broad POTASSIUM_ION_TRANSPORT View Gene Set 9.361e-06 58 0.0003678 21 Genes annotated by the GO term GO:0006813. The directed movement of potassium ions (K+) into out of within or between cells. www.broad.mit.e...
Broad METAL_ION_TRANSPORT View Gene Set 1.193e-05 116 0.0004475 22 Genes annotated by the GO term GO:0030001. The directed movement of metal ions any metal ion with an electric charge into out of within or between cells. www.broad.mit.e...
Broad CATION_TRANSPORT View Gene Set 1.745e-05 145 0.0006258 23 Genes annotated by the GO term GO:0006812. The directed movement of cations atoms or small molecules with a net positive charge into out of within or between cells. www.broad.mit.e...
Broad IMMUNE_RESPONSE View Gene Set 2.216e-05 232 0.0007618 24 Genes annotated by the GO term GO:0006955. Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. www.broad.mit.e...
Broad SECOND_MESSENGER_MEDIATED_SIGNALING View Gene Set 3.143e-05 146 0.001037 25 Genes annotated by the GO term GO:0019932. A series of molecular signals in which an ion or small molecule is formed or released into the cytosol thereby helping relay the signal within the cell. www.broad.mit.e...
Broad MONOVALENT_INORGANIC_CATION_TRANSPORT View Gene Set 3.268e-05 92 0.001037 25 Genes annotated by the GO term GO:0015672. The directed movement of inorganic cations with a valency of one into out of within or between cells. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage. www.broad.mit.e...
Broad ION_TRANSPORT View Gene Set 4.067e-05 183 0.001243 27 Genes annotated by the GO term GO:0006811. The directed movement of charged atoms or small charged molecules into out of within or between cells. www.broad.mit.e...
Broad CELL_ACTIVATION View Gene Set 5.609e-05 74 0.001653 28 Genes annotated by the GO term GO:0001775. A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. www.broad.mit.e...
Broad ANATOMICAL_STRUCTURE_MORPHOGENESIS View Gene Set 6.245e-05 375 0.001777 29 Genes annotated by the GO term GO:0009653. The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. www.broad.mit.e...
Broad SKELETAL_DEVELOPMENT View Gene Set 0.0001802 102 0.004894 30 Genes annotated by the GO term GO:0001501. The process whose specific outcome is the progression of the skeleton over time from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). www.broad.mit.e...
Broad SENSORY_PERCEPTION View Gene Set 0.0001839 190 0.004894 30 Genes annotated by the GO term GO:0007600. The series of events required for an organism to receive a sensory stimulus convert it to a molecular signal and recognize and characterize the signal. www.broad.mit.e...
Broad LEUKOCYTE_ACTIVATION View Gene Set 0.0002231 67 0.005752 32 Genes annotated by the GO term GO:0045321. A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen mitogen cytokine cellular ligand or soluble factor. www.broad.mit.e...
Broad CYTOKINE_PRODUCTION View Gene Set 0.0003698 72 0.009245 33 Genes annotated by the GO term GO:0001816. The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus resulting in an increase in its intracellular or extracellular levels. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS View Gene Set 0.0004718 66 0.01145 34 Genes annotated by the GO term GO:0051240. Any process that activates or increases the frequency rate or extent of an organismal process the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. www.broad.mit.e...
Broad SIGNAL_TRANSDUCTION View Gene Set 0.0005132 1597 0.0121 35 Genes annotated by the GO term GO:0007165. The cascade of processes by which a signal interacts with a receptor causing a change in the level or activity of a second messenger or other downstream target and ultimately effecting a change in the functioning of the cell. www.broad.mit.e...
Broad G_PROTEIN_SIGNALING_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER View Gene Set 0.0005704 98 0.01307 36 Genes annotated by the GO term GO:0007187. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand followed by modulation of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide. www.broad.mit.e...
Broad REGULATION_OF_SECRETION View Gene Set 0.0007275 40 0.01622 37 Genes annotated by the GO term GO:0051046. Any process that modulates the frequency rate or extent of the regulated release of a substance from a cell or group of cells. www.broad.mit.e...
Broad WOUND_HEALING View Gene Set 0.0008948 53 0.01943 38 Genes annotated by the GO term GO:0042060. The series of events that restore integrity to a damaged tissue following an injury. www.broad.mit.e...
Broad ION_HOMEOSTASIS View Gene Set 0.0009836 124 0.02036 39 Genes annotated by the GO term GO:0050801. Any of the processes involved in the maintenance of an internal equilibrium of ions within an organism or cell. www.broad.mit.e...
Broad CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING View Gene Set 0.0009872 100 0.02036 39 Genes annotated by the GO term GO:0019935. A series of molecular signals in which a cell uses a cyclic nucleotide to convert an extracellular signal into a response. www.broad.mit.e...
Broad CHEMICAL_HOMEOSTASIS View Gene Set 0.001207 151 0.02428 41 Genes annotated by the GO term GO:0048878. The biological processes involved in the maintenance of an internal equilibrium of a chemical. www.broad.mit.e...
Broad CATION_HOMEOSTASIS View Gene Set 0.001301 104 0.02556 42 Genes annotated by the GO term GO:0055080. The regulation of the levels transport and metabolism of cations. www.broad.mit.e...
Broad REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS View Gene Set 0.00147 15 0.02761 43 Genes annotated by the GO term GO:0032101. Any process that modulates the frequency rate or extent of a response to an external stimulus. www.broad.mit.e...
Broad CDC42_PROTEIN_SIGNAL_TRANSDUCTION View Gene Set 0.001483 13 0.02761 43 Genes annotated by the GO term GO:0032488. A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. www.broad.mit.e...
Broad LYMPHOCYTE_ACTIVATION View Gene Set 0.001506 60 0.02761 43 Genes annotated by the GO term GO:0046649. A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen mitogen cytokine chemokine cellular ligand or soluble factor. www.broad.mit.e...
Broad NEURON_DIFFERENTIATION View Gene Set 0.001585 76 0.02843 46 Genes annotated by the GO term GO:0030182. The process whereby a relatively unspecialized cell acquires specialized features of a neuron. www.broad.mit.e...
Broad CELLULAR_CATION_HOMEOSTASIS View Gene Set 0.001651 101 0.02898 47 Genes annotated by the GO term GO:0030003. The regulation of the levels transport and metabolism of cations within a cell or between a cell and its external environment. www.broad.mit.e...
Broad POSITIVE_REGULATION_OF_RESPONSE_TO_STIMULUS View Gene Set 0.00171 41 0.02939 48 Genes annotated by the GO term GO:0048584. Any process that activates maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus. www.broad.mit.e...
Broad CELL_CELL_ADHESION View Gene Set 0.00199 86 0.03333 49 Genes annotated by the GO term GO:0016337. The attachment of one cell to another cell via adhesion molecules. www.broad.mit.e...
Broad REGULATION_OF_IMMUNE_SYSTEM_PROCESS View Gene Set 0.00202 67 0.03333 49 Genes annotated by the GO term GO:0002682. Any process that modulates the frequency rate or extent of an immune system process. www.broad.mit.e...
Broad REGULATION_OF_RESPONSE_TO_STIMULUS View Gene Set 0.002154 59 0.03485 51 Genes annotated by the GO term GO:0048583. Any process that modulates the frequency rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus. www.broad.mit.e...
Broad FEEDING_BEHAVIOR View Gene Set 0.002349 24 0.03727 52 Genes annotated by the GO term GO:0007631. Behavior associated with the intake of food. www.broad.mit.e...
Broad DETECTION_OF_EXTERNAL_STIMULUS View Gene Set 0.002419 23 0.03765 53 Genes annotated by the GO term GO:0009581. The series of events in which an external stimulus is received by a cell and converted into a molecular signal. www.broad.mit.e...
Broad REGULATION_OF_CYTOKINE_SECRETION View Gene Set 0.002701 16 0.03975 54 Genes annotated by the GO term GO:0050707. Any process that modulates the frequency rate or extent of the regulated release of cytokines from a cell or group of cells. www.broad.mit.e...
Broad DETECTION_OF_ABIOTIC_STIMULUS View Gene Set 0.002654 19 0.03975 54 Genes annotated by the GO term GO:0009582. The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. www.broad.mit.e...
Broad CELLULAR_MORPHOGENESIS_DURING_DIFFERENTIATION View Gene Set 0.002794 49 0.03975 54 Genes annotated by the GO term GO:0000904. The change in form (cell shape and size) that occurs when relatively unspecialized cells e.g. embryonic or regenerative cells acquire specialized structural and/or functional features that characterize the cells tissues or organs of the mature organism or some other relatively stable phase of the organism's life history. www.broad.mit.e...
Broad GENERATION_OF_NEURONS View Gene Set 0.002755 83 0.03975 54 Genes annotated by the GO term GO:0048699. The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. www.broad.mit.e...
Broad CELLULAR_HOMEOSTASIS View Gene Set 0.002725 141 0.03975 54 Genes annotated by the GO term GO:0019725. The processes involved in the maintenance of an internal equilibrium at the level of the cell. www.broad.mit.e...
Broad NEURITE_DEVELOPMENT View Gene Set 0.003057 53 0.04275 59 Genes annotated by the GO term GO:0031175. The process whose specific outcome is the progression of the neurite over time from its formation to the mature structure. The neurite is any process extending from a neural cell such as axons or dendrites. www.broad.mit.e...
Broad TISSUE_DEVELOPMENT View Gene Set 0.003577 137 0.04838 60 Genes annotated by the GO term GO:0009888. The process whose specific outcome is the progression of a tissue over time from its formation to the mature structure. www.broad.mit.e...
Broad NEURON_DEVELOPMENT View Gene Set 0.003542 61 0.04838 60 Genes annotated by the GO term GO:0048666. The process whose specific outcome is the progression of a neuron over time from initial commitment of the cell to a specific fate to the fully functional differentiated cell. www.broad.mit.e...
Broad EXTRACELLULAR_STRUCTURE_ORGANIZATION_AND_BIOGENESIS View Gene Set 0.003649 32 0.04856 62 Genes annotated by the GO term GO:0043062. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane and also covers the host cell environment outside an intracellular parasite. www.broad.mit.e...
Broad REGULATION_OF_HORMONE_SECRETION View Gene Set 0.003801 14 0.04977 63 Genes annotated by the GO term GO:0046883. Any process that modulates the frequency rate or extent of the regulated release of a hormone from a cell or group of cells. www.broad.mit.e...

Gene Set Collection: Broad.c5.CC

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad EXTRACELLULAR_REGION View Gene Set 4.146e-17 437 9.659e-15 1 Genes annotated by the GO term GO:0005576. The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. www.broad.mit.e...
Broad PLASMA_MEMBRANE_PART View Gene Set 6.683e-15 1142 7.786e-13 2 Genes annotated by the GO term GO:0044459. Any constituent part of the plasma membrane the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. www.broad.mit.e...
Broad EXTRACELLULAR_REGION_PART View Gene Set 1.047e-13 331 6.102e-12 3 Genes annotated by the GO term GO:0044421. Any constituent part of the extracellular region the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite. www.broad.mit.e...
Broad PLASMA_MEMBRANE View Gene Set 1.022e-13 1392 6.102e-12 3 Genes annotated by the GO term GO:0005886. The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. www.broad.mit.e...
Broad INTRINSIC_TO_PLASMA_MEMBRANE View Gene Set 3.582e-13 978 1.669e-11 5 Genes annotated by the GO term GO:0031226. Located in the plasma membrane such that some covalently attached portion of the gene product for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor spans or is embedded in one or both leaflets of the membrane. www.broad.mit.e...
Broad INTEGRAL_TO_PLASMA_MEMBRANE View Gene Set 1.52e-12 964 5.901e-11 6 Genes annotated by the GO term GO:0005887. Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. www.broad.mit.e...
Broad EXTRACELLULAR_SPACE View Gene Set 2.384e-11 239 7.934e-10 7 Genes annotated by the GO term GO:0005615. That part of a multicellular organism outside the cells proper usually taken to be outside the plasma membranes and occupied by fluid. www.broad.mit.e...
Broad INTRINSIC_TO_MEMBRANE View Gene Set 4.071e-08 1319 1.186e-06 8 Genes annotated by the GO term GO:0031224. Located in a membrane such that some covalently attached portion of the gene product for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor spans or is embedded in one or both leaflets of the membrane. www.broad.mit.e...
Broad INTEGRAL_TO_MEMBRANE View Gene Set 9.044e-08 1301 2.342e-06 9 Genes annotated by the GO term GO:0016021. Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein indicates that all or part of the peptide sequence is embedded in the membrane. www.broad.mit.e...
Broad VOLTAGE_GATED_POTASSIUM_CHANNEL_COMPLEX View Gene Set 2.478e-05 40 0.0005774 10 Genes annotated by the GO term GO:0008076. A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential. www.broad.mit.e...
Broad COLLAGEN View Gene Set 4.025e-05 23 0.0008526 11 Genes annotated by the GO term GO:0005581. Any of the various assemblies in which collagen chains form a left-handed triple helix; may assemble into higher order structures. www.broad.mit.e...
Broad PROTEINACEOUS_EXTRACELLULAR_MATRIX View Gene Set 4.735e-05 98 0.0009193 12 Genes annotated by the GO term GO:0005578. A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. www.broad.mit.e...
Broad EXTRACELLULAR_MATRIX View Gene Set 6.846e-05 100 0.001227 13 Genes annotated by the GO term GO:0031012. A structure lying external to one or more cells which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants). www.broad.mit.e...
Broad MEMBRANE_PART View Gene Set 0.0002933 1632 0.004882 14 Genes annotated by the GO term GO:0044425. Any constituent part of a membrane a double layer of lipid molecules that encloses all cells and in eukaryotes many organelles; may be a single or double lipid bilayer; also includes associated proteins. www.broad.mit.e...
Broad MEMBRANE View Gene Set 0.001794 1939 0.02786 15 Genes annotated by the GO term GO:0016020. Double layer of lipid molecules that encloses all cells and in eukaryotes many organelles; may be a single or double lipid bilayer; also includes associated proteins. www.broad.mit.e...

Gene Set Collection: Broad.c5.MF

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Broad TRANSMEMBRANE_RECEPTOR_ACTIVITY View Gene Set 1.745e-12 411 6.909e-10 1 Genes annotated by the GO term GO:0004888. Combining with an extracellular or intracellular messenger to initiate a change in cell activity and spanning to the membrane of either the cell or an organelle. www.broad.mit.e...
Broad RECEPTOR_ACTIVITY View Gene Set 1.524e-10 572 3.017e-08 2 Genes annotated by the GO term GO:0004872. Combining with an extracellular or intracellular messenger to initiate a change in cell activity. www.broad.mit.e...
Broad ION_CHANNEL_ACTIVITY View Gene Set 4.334e-09 147 5.721e-07 3 Genes annotated by the GO term GO:0005216. Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. www.broad.mit.e...
Broad GATED_CHANNEL_ACTIVITY View Gene Set 1.101e-08 121 8.721e-07 4 Genes annotated by the GO term GO:0022836. Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus. www.broad.mit.e...
Broad SUBSTRATE_SPECIFIC_CHANNEL_ACTIVITY View Gene Set 1.012e-08 154 8.721e-07 4 Genes annotated by the GO term GO:0022838. Catalysis of energy-independent facilitated diffusion mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules. www.broad.mit.e...
Broad CATION_CHANNEL_ACTIVITY View Gene Set 1.54e-08 118 1.017e-06 6 Genes annotated by the GO term GO:0005261. Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient. www.broad.mit.e...
Broad G_PROTEIN_COUPLED_RECEPTOR_ACTIVITY View Gene Set 2.426e-08 185 1.373e-06 7 Genes annotated by the GO term GO:0004930. A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers. www.broad.mit.e...
Broad RHODOPSIN_LIKE_RECEPTOR_ACTIVITY View Gene Set 6.339e-08 131 3.138e-06 8 Genes annotated by the GO term GO:0001584. A G-protein coupled receptor that is structurally/functionally related to the rhodopsin receptor. www.broad.mit.e...
Broad METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY View Gene Set 1.808e-07 145 7.954e-06 9 Genes annotated by the GO term GO:0046873. Catalysis of the transfer of metal ions from one side of a membrane to the other. www.broad.mit.e...
Broad VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY View Gene Set 2.1e-07 66 8.314e-06 10 Genes annotated by the GO term GO:0022843. Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. www.broad.mit.e...
Broad VOLTAGE_GATED_CHANNEL_ACTIVITY View Gene Set 8.539e-07 73 3.074e-05 11 Genes annotated by the GO term GO:0022832. Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded. www.broad.mit.e...
Broad G_PROTEIN_COUPLED_RECEPTOR_BINDING View Gene Set 1.506e-05 54 0.000497 12 Genes annotated by the GO term GO:0001664. Interacting selectively with a G-protein-coupled receptor. www.broad.mit.e...
Broad VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY View Gene Set 1.765e-05 36 0.0005376 13 Genes annotated by the GO term GO:0005249. Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel. www.broad.mit.e...
Broad POTASSIUM_CHANNEL_ACTIVITY View Gene Set 2.326e-05 50 0.0006579 14 Genes annotated by the GO term GO:0005267. Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. www.broad.mit.e...
Broad RECEPTOR_BINDING View Gene Set 3.603e-05 373 0.0009511 15 Genes annotated by the GO term GO:0005102. Interacting selectively with one or more specific sites on a receptor molecule a macromolecule that undergoes combination with a hormone neurotransmitter drug or intracellular messenger to initiate a change in cell function. www.broad.mit.e...
Broad ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY View Gene Set 5.378e-05 275 0.001331 16 Genes annotated by the GO term GO:0015075. Catalysis of the transfer of an ion from one side of a membrane to the other. www.broad.mit.e...
Broad CHEMOKINE_RECEPTOR_BINDING View Gene Set 7.352e-05 43 0.001627 17 Genes annotated by the GO term GO:0042379. Interacting selectively with any chemokine receptor. www.broad.mit.e...
Broad SERINE_TYPE_ENDOPEPTIDASE_ACTIVITY View Gene Set 7.397e-05 39 0.001627 17 Genes annotated by the GO term GO:0004252. Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). www.broad.mit.e...
Broad CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY View Gene Set 0.0001112 211 0.002318 19 Genes annotated by the GO term GO:0008324. Catalysis of the transfer of cation from one side of the membrane to the other. www.broad.mit.e...
Broad CHEMOKINE_ACTIVITY View Gene Set 0.0001189 42 0.002355 20 Genes annotated by the GO term GO:0008009. The function of a family of chemotactic pro-inflammatory activation-inducible cytokines acting primarily upon hemopoietic cells in immunoregulatory processes; all chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. www.broad.mit.e...
Broad SERINE_HYDROLASE_ACTIVITY View Gene Set 0.0001492 44 0.002814 21 Genes annotated by the GO term GO:0017171. Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). www.broad.mit.e...
Broad SERINE_TYPE_PEPTIDASE_ACTIVITY View Gene Set 0.0002177 43 0.003919 22 Genes annotated by the GO term GO:0008236. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). www.broad.mit.e...
Broad PEPTIDE_RECEPTOR_ACTIVITY View Gene Set 0.0003782 50 0.00624 23 Genes annotated by the GO term GO:0001653. Combining with an extracellular or intracellular peptide to initiate a change in cell activity. www.broad.mit.e...
Broad CYTOKINE_ACTIVITY View Gene Set 0.000374 111 0.00624 23 Genes annotated by the GO term GO:0005125. Functions to control the survival growth differentiation and effector function of tissues and cells. www.broad.mit.e...
Broad LIGAND_GATED_CHANNEL_ACTIVITY View Gene Set 0.0008467 39 0.01341 25 Genes annotated by the GO term GO:0022834. Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. www.broad.mit.e...
Broad NEUROTRANSMITTER_RECEPTOR_ACTIVITY View Gene Set 0.001497 50 0.02281 26 Genes annotated by the GO term GO:0030594. Combining with a neurotransmitter to initiate a change in cell activity. www.broad.mit.e...
Broad NEUROTRANSMITTER_BINDING View Gene Set 0.00167 53 0.02449 27 Genes annotated by the GO term GO:0042165. Interacting selectively with a neurotransmitter any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. www.broad.mit.e...
Broad EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT View Gene Set 0.001812 27 0.02563 28 Genes annotated by the GO term GO:0005201. The action of a molecule that contributes to the structural integrity of the extracellular matrix. www.broad.mit.e...
Broad HORMONE_ACTIVITY View Gene Set 0.002107 44 0.02877 29 Genes annotated by the GO term GO:0005179. The action characteristic of a hormone any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants and to synthetic substances having comparable effects. www.broad.mit.e...
Broad HEMATOPOIETIN_INTERFERON_CLASSD200_DOMAIN_CYTOKINE_RECEPTOR_BINDING View Gene Set 0.00233 29 0.02983 30 Genes annotated by the GO term GO:0005126. www.broad.mit.e...
Broad SULFOTRANSFERASE_ACTIVITY View Gene Set 0.002335 27 0.02983 30 Genes annotated by the GO term GO:0008146. Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate. www.broad.mit.e...
Broad CALCIUM_CHANNEL_ACTIVITY View Gene Set 0.002579 33 0.03191 32 Genes annotated by the GO term GO:0005262. Catalysis of facilitated diffusion of an calcium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. www.broad.mit.e...
Broad MONOOXYGENASE_ACTIVITY View Gene Set 0.002916 29 0.03499 33 Genes annotated by the GO term GO:0004497. Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. www.broad.mit.e...
Broad VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY View Gene Set 0.003081 18 0.03589 34 Genes annotated by the GO term GO:0005245. Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel. www.broad.mit.e...
Broad GROWTH_FACTOR_ACTIVITY View Gene Set 0.003286 54 0.03718 35 Genes annotated by the GO term GO:0008083. The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation. www.broad.mit.e...
Broad CARBOHYDRATE_BINDING View Gene Set 0.003593 72 0.03861 36 Genes annotated by the GO term GO:0030246. Interacting selectively with any carbohydrate. www.broad.mit.e...
Broad AMINE_RECEPTOR_ACTIVITY View Gene Set 0.003608 34 0.03861 36 Genes annotated by the GO term GO:0008227. Combining with a biogenic amine to initiate a change in cell activity. www.broad.mit.e...
Broad GROWTH_FACTOR_BINDING View Gene Set 0.003786 32 0.03945 38 Genes annotated by the GO term GO:0019838. Interacting selectively with any growth factor proteins or polypeptides that stimulate a cell or organism to grow or proliferate. www.broad.mit.e...
Broad 3_5_CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY View Gene Set 0.003974 13 0.04035 39 Genes annotated by the GO term GO:0004114. Catalysis of the reaction: nucleoside 3' 5'-cyclic phosphate + H2O = nucleoside 5'-phosphate. www.broad.mit.e...

Gene Set Collection: PMID

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
PMID 20237496 View Gene Set 1.435e-11 828 3.598e-08 1 New genetic associations detected in a host response study to hepatitis B vaccine. www.ncbi.nlm.ni...
PMID 19086053 View Gene Set 8.621e-11 301 1.081e-07 2 Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. www.ncbi.nlm.ni...
PMID 20503287 View Gene Set 6.682e-10 205 5.584e-07 3 Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. www.ncbi.nlm.ni...
PMID 17703412 View Gene Set 8.97e-10 207 5.622e-07 4 Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. www.ncbi.nlm.ni...
PMID 19258923 View Gene Set 1.337e-09 205 6.703e-07 5 Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. www.ncbi.nlm.ni...
PMID 12975309 View Gene Set 4.512e-09 1000 1.885e-06 6 The secreted protein discovery initiative (SPDI) a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. www.ncbi.nlm.ni...
PMID 20452482 View Gene Set 6.753e-09 188 2.418e-06 7 Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. www.ncbi.nlm.ni...
PMID 18240029 View Gene Set 8.854e-09 203 2.775e-06 8 Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. www.ncbi.nlm.ni...
PMID 16335952 View Gene Set 1.913e-08 257 5.329e-06 9 Human plasma N-glycoproteome analysis by immunoaffinity subtraction hydrazide chemistry and mass spectrometry. www.ncbi.nlm.ni...
PMID 14983052 View Gene Set 1.801e-07 391 4.515e-05 10 The human olfactory receptor gene family. www.ncbi.nlm.ni...
PMID 15340161 View Gene Set 7.369e-07 264 0.0001539 11 Signal peptide prediction based on analysis of experimentally verified cleavage sites. www.ncbi.nlm.ni...
PMID 2286373 View Gene Set 7.207e-07 12 0.0001539 11 Human metallothionein genes: structure of the functional locus at 16q13. www.ncbi.nlm.ni...
PMID 20424473 View Gene Set 1.865e-06 146 0.0003596 13 L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms. www.ncbi.nlm.ni...
PMID 19247692 View Gene Set 4.329e-06 92 0.0007752 14 Analyses of associations with asthma in four asthma population samples from Canada and Australia. www.ncbi.nlm.ni...
PMID 19453261 View Gene Set 6.329e-06 383 0.001058 15 High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. www.ncbi.nlm.ni...
PMID 18974842 View Gene Set 1.187e-05 46 0.00186 16 Gender differences in genetic risk profiles for cardiovascular disease. www.ncbi.nlm.ni...
PMID 15128046 View Gene Set 1.341e-05 60 0.001978 17 Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes including nomenclature recommendations for genes pseudogenes and alternative-splice variants. www.ncbi.nlm.ni...
PMID 19420105 View Gene Set 1.542e-05 81 0.002147 18 A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN). www.ncbi.nlm.ni...
PMID 19578796 View Gene Set 2.015e-05 152 0.002659 19 Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. www.ncbi.nlm.ni...
PMID 19336475 View Gene Set 2.23e-05 76 0.002796 20 Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk. www.ncbi.nlm.ni...
PMID 19131662 View Gene Set 3.256e-05 64 0.003887 21 A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. www.ncbi.nlm.ni...
PMID 12871600 View Gene Set 4.384e-05 22 0.004996 22 Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen. www.ncbi.nlm.ni...
PMID 11048639 View Gene Set 4.637e-05 29 0.005055 23 The mechanism of phospholipase C-gamma1 regulation. www.ncbi.nlm.ni...
PMID 12815422 View Gene Set 5.248e-05 239 0.005482 24 The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. www.ncbi.nlm.ni...
PMID 11827988 View Gene Set 6.052e-05 25 0.005835 25 Adapters in lymphocyte signaling. www.ncbi.nlm.ni...
PMID 16382104 View Gene Set 5.969e-05 40 0.005835 25 International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. www.ncbi.nlm.ni...
PMID 19948975 View Gene Set 6.7e-05 229 0.006221 27 Integrative predictive model of coronary artery calcification in atherosclerosis. www.ncbi.nlm.ni...
PMID 17652306 View Gene Set 7.056e-05 28 0.006318 28 Keeping the (kinase) party going: SLP-76 and ITK dance to the beat. www.ncbi.nlm.ni...
PMID 19263529 View Gene Set 7.568e-05 57 0.006432 29 Genetic risk factors in recurrent venous thromboembolism: A multilocus population-based prospective approach. www.ncbi.nlm.ni...
PMID 19874574 View Gene Set 7.697e-05 130 0.006432 29 Genetical genomic determinants of alcohol consumption in rats and humans. www.ncbi.nlm.ni...
PMID 15489916 View Gene Set 9.433e-05 24 0.00739 31 Function of the Src-family kinases Lck and Fyn in T-cell development and activation. www.ncbi.nlm.ni...
PMID 9242638 View Gene Set 9.249e-05 14 0.00739 31 Differential interactions of Id proteins with basic-helix-loop-helix transcription factors. www.ncbi.nlm.ni...
PMID 18834073 View Gene Set 0.0001406 18 0.01068 33 Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux. www.ncbi.nlm.ni...
PMID 18519826 View Gene Set 0.0001737 101 0.01281 34 Molecular genetics of successful smoking cessation: convergent genome-wide association study results. www.ncbi.nlm.ni...
PMID 12514663 View Gene Set 0.0001868 12 0.01338 35 Potential thrombophilic mutations/polymorphisms in patients with no flow-limiting stenosis after myocardial infarction. www.ncbi.nlm.ni...
PMID 19240061 View Gene Set 0.0002156 267 0.01422 36 Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. www.ncbi.nlm.ni...
PMID 1973146 View Gene Set 0.0002155 43 0.01422 36 Nomenclature for human homeobox genes. www.ncbi.nlm.ni...
PMID 19860767 View Gene Set 0.0002119 13 0.01422 36 Genetic cardiovascular risk factors and age-related macular degeneration. www.ncbi.nlm.ni...
PMID 20161734 View Gene Set 0.0002247 16 0.01444 39 Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants. www.ncbi.nlm.ni...
PMID 12679517 View Gene Set 0.0002626 31 0.01646 40 The G protein-coupled receptor repertoires of human and mouse. www.ncbi.nlm.ni...
PMID 11083865 View Gene Set 0.000314 12 0.01799 41 Versican interacts with chemokines and modulates cellular responses. www.ncbi.nlm.ni...
PMID 1358459 View Gene Set 0.0003517 40 0.01799 41 Vertebrate homeobox gene nomenclature. www.ncbi.nlm.ni...
PMID 15076187 View Gene Set 0.0003504 13 0.01799 41 Genetic influences on blood pressure within the Stanislas Cohort. www.ncbi.nlm.ni...
PMID 17111197 View Gene Set 0.0003398 10 0.01799 41 A comprehensive analysis of 12 thrombophilic mutations and related parameters in patients with inflammatory bowel disease: data from Turkey. www.ncbi.nlm.ni...
PMID 19072566 View Gene Set 0.0003398 10 0.01799 41 Prevalence of prothrombotic polymorphisms in Greece. www.ncbi.nlm.ni...
PMID 19906129 View Gene Set 0.0003398 10 0.01799 41 A prospective case-control study analyzes 12 thrombophilic gene mutations in Turkish couples with recurrent pregnancy loss. www.ncbi.nlm.ni...
PMID 20346360 View Gene Set 0.0003452 94 0.01799 41 Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. www.ncbi.nlm.ni...
PMID 20425806 View Gene Set 0.0003398 10 0.01799 41 Vascular at-risk genotypes and disease severity in Lebanese sickle cell disease patients. www.ncbi.nlm.ni...
PMID 20468064 View Gene Set 0.00032 182 0.01799 41 Association study of 182 candidate genes in anorexia nervosa. www.ncbi.nlm.ni...
PMID 14760718 View Gene Set 0.0003744 47 0.01877 50 Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. www.ncbi.nlm.ni...
PMID 14718574 View Gene Set 0.0003826 166 0.01881 51 The human plasma proteome: a nonredundant list developed by combination of four separate sources. www.ncbi.nlm.ni...
PMID 11181995 View Gene Set 0.000455 511 0.02121 52 The sequence of the human genome. www.ncbi.nlm.ni...
PMID 14706682 View Gene Set 0.0004568 10 0.02121 52 Genetic polymorphisms associated with thrombophilia and vascular disease in women with unexplained late intrauterine fetal death: a multicenter study. www.ncbi.nlm.ni...
PMID 19308021 View Gene Set 0.0004508 18 0.02121 52 Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort. www.ncbi.nlm.ni...
PMID 1869305 View Gene Set 0.0005071 14 0.0227 55 Interaction of CD4 with HLA class II antigens and HIV gp120. www.ncbi.nlm.ni...
PMID 7512597 View Gene Set 0.0005071 14 0.0227 55 HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4. www.ncbi.nlm.ni...
PMID 10661406 View Gene Set 0.000529 18 0.02287 57 Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection. www.ncbi.nlm.ni...
PMID 11118314 View Gene Set 0.000529 18 0.02287 57 Reciprocal modulation of transcriptional activities between HIV-1 Tat and MHC class II transactivator CIITA. www.ncbi.nlm.ni...
PMID 11857506 View Gene Set 0.0005408 38 0.02298 59 Complete mutation analysis panel of the 39 human HOX genes. www.ncbi.nlm.ni...
PMID 10391209 View Gene Set 0.0006657 67 0.02528 60 Characterization of single-nucleotide polymorphisms in coding regions of human genes. www.ncbi.nlm.ni...
PMID 10729169 View Gene Set 0.0006526 15 0.02528 60 Efficient incorporation of HLA class II onto human immunodeficiency virus type 1 requires envelope glycoprotein packaging. www.ncbi.nlm.ni...
PMID 19559392 View Gene Set 0.0006595 52 0.02528 60 A candidate gene association study of 77 polymorphisms in migraine. www.ncbi.nlm.ni...
PMID 3489470 View Gene Set 0.0006526 15 0.02528 60 AIDS and related syndromes as a viral-induced autoimmune disease of the immune system: an anti-MHC II disorder. Therapeutic implications. www.ncbi.nlm.ni...
PMID 7602119 View Gene Set 0.0006526 15 0.02528 60 Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and role in processing for association with class II MHC. www.ncbi.nlm.ni...
PMID 8376762 View Gene Set 0.0006526 15 0.02528 60 HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II-restricted T lymphocytes. www.ncbi.nlm.ni...
PMID 9079699 View Gene Set 0.0006526 15 0.02528 60 The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway. www.ncbi.nlm.ni...
PMID 11060466 View Gene Set 0.0006878 10 0.02574 67 Clustering of two fragile sites and seven homeobox genes in human chromosome region 2q31-->q32.1. www.ncbi.nlm.ni...
PMID 11714857 View Gene Set 0.0007144 12 0.02634 68 Genetic influences on lipid metabolism trait variability within the Stanislas Cohort. www.ncbi.nlm.ni...
PMID 18633131 View Gene Set 0.0007456 44 0.02709 69 Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era. www.ncbi.nlm.ni...
PMID 11347906 View Gene Set 0.0007873 106 0.02791 70 Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. www.ncbi.nlm.ni...
PMID 16928730 View Gene Set 0.0008014 11 0.02791 70 Identifying genetic susceptibilities to diabetes-related complications among individuals at low risk of complications: An application of tree-structured survival analysis. www.ncbi.nlm.ni...
PMID 18927546 View Gene Set 0.000797 17 0.02791 70 Lp(a) and risk of recurrent cardiac events in obese postinfarction patients. www.ncbi.nlm.ni...
PMID 12446192 View Gene Set 0.0008257 15 0.02798 73 Analysis of several hundred genetic polymorphisms may improve assessment of the individual genetic burden for coronary artery disease. www.ncbi.nlm.ni...
PMID 12539042 View Gene Set 0.0008178 45 0.02798 73 HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. www.ncbi.nlm.ni...
PMID 17903302 View Gene Set 0.0009112 32 0.03046 75 Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. www.ncbi.nlm.ni...
PMID 19197348 View Gene Set 0.000934 59 0.03081 76 Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. www.ncbi.nlm.ni...
PMID 1967269 View Gene Set 0.0009849 15 0.03165 77 HIV-gp120 can block CD4-class II MHC-mediated adhesion. www.ncbi.nlm.ni...
PMID 8168144 View Gene Set 0.0009849 15 0.03165 77 Envelope glycoproteins of HIV-1 interfere with T-cell-dependent B cell differentiation: role of CD4-MHC class II interaction in the effector phase of T cell help. www.ncbi.nlm.ni...
PMID 19729601 View Gene Set 0.001007 64 0.03196 79 Candidate gene polymorphisms for ischemic stroke. www.ncbi.nlm.ni...
PMID 10391210 View Gene Set 0.00103 16 0.03227 80 Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. www.ncbi.nlm.ni...
PMID 19479237 View Gene Set 0.001049 57 0.03246 81 Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling. www.ncbi.nlm.ni...
PMID 1978941 View Gene Set 0.001187 16 0.03525 82 Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules. www.ncbi.nlm.ni...
PMID 20036902 View Gene Set 0.0012 10 0.03525 82 Hemostatic gene polymorphisms in young Sardinian with non-fatal acute myocardial infarction. www.ncbi.nlm.ni...
PMID 2543930 View Gene Set 0.001187 16 0.03525 82 Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding. www.ncbi.nlm.ni...
PMID 2846691 View Gene Set 0.001187 16 0.03525 82 Inhibition of CD4+ T cell function by the HIV envelope protein gp120. www.ncbi.nlm.ni...
PMID 8432525 View Gene Set 0.001209 20 0.03525 82 Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers. www.ncbi.nlm.ni...
PMID 17490516 View Gene Set 0.001256 12 0.0362 87 [Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia]. www.ncbi.nlm.ni...
PMID 11341749 View Gene Set 0.001281 15 0.0365 88 Candidate gene polymorphisms in cardiovascular disease: a comparative study of frequencies between a French and an Italian population. www.ncbi.nlm.ni...
PMID 12213199 View Gene Set 0.001314 216 0.0366 89 DEFOG: a practical scheme for deciphering families of genes. www.ncbi.nlm.ni...
PMID 18992263 View Gene Set 0.00131 25 0.0366 89 Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways. www.ncbi.nlm.ni...
PMID 12563287 View Gene Set 0.001352 14 0.03685 91 NALPs: a novel protein family involved in inflammation. www.ncbi.nlm.ni...
PMID 20403135 View Gene Set 0.001352 14 0.03685 91 The genetics of NOD-like receptors in Crohn's disease. www.ncbi.nlm.ni...
PMID 8450224 View Gene Set 0.001465 10 0.0395 93 HIV-gp 160-induced T cell-dependent B cell differentiation. Role of T cell-B cell activation molecule and IL-6. www.ncbi.nlm.ni...
PMID 19598235 View Gene Set 0.001713 67 0.04569 94 Genes related to sex steroids neural growth and social-emotional behavior are associated with autistic traits empathy and Asperger syndrome. www.ncbi.nlm.ni...
PMID 18174230 View Gene Set 0.001742 53 0.04597 95 Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus. www.ncbi.nlm.ni...
PMID 12194848 View Gene Set 0.001808 13 0.04721 96 Twenty pairs of sox: extent homology and nomenclature of the mouse and human sox transcription factor gene families. www.ncbi.nlm.ni...
PMID 11543631 View Gene Set 0.001875 12 0.04845 97 Genomic analysis of synaptotagmin genes. www.ncbi.nlm.ni...
PMID 19046302 View Gene Set 0.001911 18 0.04889 98 Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians. www.ncbi.nlm.ni...

Gene Set Collection: Prosite

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null PS50835 View Gene Set 1.939e-21 658 1.425e-18 1 IG_LIKE expasy.org/pros...
Null PS50262 View Gene Set 5.329e-18 765 1.958e-15 2 G_PROTEIN_RECEP_F1_2 expasy.org/pros...
Null PS00237 View Gene Set 4.261e-15 555 1.034e-12 3 G_PROTEIN_RECEP_F1_1 expasy.org/pros...
Null PS50026 View Gene Set 5.627e-15 207 1.034e-12 3 EGF_3 expasy.org/pros...
Null PS50071 View Gene Set 4.644e-14 264 6.827e-12 5 HOMEOBOX_2 expasy.org/pros...
Null PS00027 View Gene Set 1.099e-13 197 1.347e-11 6 HOMEOBOX_1 expasy.org/pros...
Null PS01186 View Gene Set 3.49e-12 171 3.665e-10 7 EGF_2 expasy.org/pros...
Null PS00022 View Gene Set 1.287e-10 151 1.182e-08 8 EGF_1 expasy.org/pros...
Null PS50853 View Gene Set 1.741e-09 181 1.422e-07 9 FN3 expasy.org/pros...
Null PS50092 View Gene Set 2.897e-08 68 2.129e-06 10 TSP1 expasy.org/pros...
Null PS00203 View Gene Set 3.283e-08 13 2.194e-06 11 METALLOTHIONEIN_VRT expasy.org/pros...
Null PS00010 View Gene Set 7.167e-08 103 4.052e-06 12 ASX_HYDROXYL expasy.org/pros...
Null PS50240 View Gene Set 6.877e-08 122 4.052e-06 12 TRYPSIN_DOM expasy.org/pros...
Null PS00135 View Gene Set 1.005e-07 99 5.274e-06 14 TRYPSIN_SER expasy.org/pros...
Null PS01208 View Gene Set 1.386e-07 34 6.793e-06 15 VWFC_1 expasy.org/pros...
Null PS01187 View Gene Set 3.418e-07 99 1.57e-05 16 EGF_CA expasy.org/pros...
Null PS00134 View Gene Set 4.29e-07 104 1.855e-05 17 TRYPSIN_HIS expasy.org/pros...
Null PS50184 View Gene Set 6.118e-07 35 2.498e-05 18 VWFC_2 expasy.org/pros...
Null PS00086 View Gene Set 1.175e-05 55 0.0004408 19 CYTOCHROME_P450 expasy.org/pros...
Null PS50923 View Gene Set 1.199e-05 57 0.0004408 19 SUSHI expasy.org/pros...
Null PS00284 View Gene Set 2.997e-05 33 0.001049 21 SERPIN expasy.org/pros...
Null PS00109 View Gene Set 5.99e-05 98 0.002001 22 PROTEIN_KINASE_TYR expasy.org/pros...
Null PS50088 View Gene Set 0.0001104 273 0.00353 23 ANK_REPEAT expasy.org/pros...
Null PS50004 View Gene Set 0.0001181 115 0.003616 24 C2 expasy.org/pros...
Null PS50297 View Gene Set 0.0001364 285 0.004011 25 ANK_REP_REGION expasy.org/pros...
Null PS50189 View Gene Set 0.0001597 26 0.004515 26 NTR expasy.org/pros...
Null PS50041 View Gene Set 0.000185 88 0.005037 27 C_TYPE_LECTIN_2 expasy.org/pros...
Null PS00290 View Gene Set 0.0002107 86 0.005163 28 IG_MHC expasy.org/pros...
Null PS50025 View Gene Set 0.0002088 41 0.005163 28 LAM_G_DOMAIN expasy.org/pros...
Null PS50824 View Gene Set 0.0002006 23 0.005163 28 DAPIN expasy.org/pros...
Null PS00236 View Gene Set 0.0002274 45 0.005391 31 NEUROTR_ION_CHANNEL expasy.org/pros...
Null PS50234 View Gene Set 0.0002823 70 0.006483 32 VWFA expasy.org/pros...
Null PS50003 View Gene Set 0.0003288 259 0.007322 33 PH_DOMAIN expasy.org/pros...
Null PS50024 View Gene Set 0.000469 19 0.01014 34 SEA expasy.org/pros...
Null PS50837 View Gene Set 0.0005168 23 0.01085 35 NACHT expasy.org/pros...
Null PS00472 View Gene Set 0.0005592 24 0.01142 36 SMALL_CYTOKINES_CC expasy.org/pros...
Null PS51041 View Gene Set 0.0006173 17 0.01226 37 EMI expasy.org/pros...
Null PS50010 View Gene Set 0.0006748 71 0.01305 38 DH_2 expasy.org/pros...
Null PS00250 View Gene Set 0.0007424 33 0.01385 39 TGF_BETA_1 expasy.org/pros...
Null PS01225 View Gene Set 0.0007727 24 0.01385 39 CTCK_2 expasy.org/pros...
Null PS50042 View Gene Set 0.0007556 38 0.01385 39 CNMP_BINDING_3 expasy.org/pros...
Null PS50888 View Gene Set 0.0008401 114 0.0147 42 HLH expasy.org/pros...
Null PS50106 View Gene Set 0.0009397 153 0.01606 43 PDZ expasy.org/pros...
Null PS00610 View Gene Set 0.001133 19 0.01892 44 NA_NEUROTRAN_SYMP_1 expasy.org/pros...
Null PS51055 View Gene Set 0.001171 8 0.01912 45 ITAM_1 expasy.org/pros...
Null PS51362 View Gene Set 0.001199 39 0.01915 46 TGF_BETA_2 expasy.org/pros...
Null PS50267 View Gene Set 0.001276 20 0.01996 47 NA_NEUROTRAN_SYMP_3 expasy.org/pros...
Null PS00754 View Gene Set 0.001357 18 0.02078 48 NA_NEUROTRAN_SYMP_2 expasy.org/pros...
Null PS00246 View Gene Set 0.001598 19 0.02349 49 WNT1 expasy.org/pros...
Null PS00477 View Gene Set 0.001594 11 0.02349 49 ALPHA_2_MACROGLOBULIN expasy.org/pros...
Null PS50900 View Gene Set 0.001912 22 0.02755 51 PLAC expasy.org/pros...
Null PS51323 View Gene Set 0.002723 20 0.03849 52 IGFBP_N_2 expasy.org/pros...
Null PS50022 View Gene Set 0.003153 25 0.04372 53 FA58C_3 expasy.org/pros...
Null PS00226 View Gene Set 0.003389 69 0.04612 54 IF expasy.org/pros...
Null PS50200 View Gene Set 0.003642 40 0.04867 55 RA expasy.org/pros...

Gene Set Collection: pathwayCommons.reactome

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null Signaling by GPCR View Gene Set 1.345e-21 802 1.503e-18 1 REACTOME - Signaling by GPCR gene set www.pathwaycomm...
Null GPCR ligand binding View Gene Set 2.315e-14 339 1.293e-11 2 REACTOME - GPCR ligand binding gene set www.pathwaycomm...
Null Class A/1 (Rhodopsin-like receptors) View Gene Set 1.183e-11 277 3.759e-09 3 REACTOME - Class A/1 (Rhodopsin-like receptors) gene set www.pathwaycomm...
Null GPCR downstream signaling View Gene Set 1.346e-11 595 3.759e-09 3 REACTOME - GPCR downstream signaling gene set www.pathwaycomm...
Null Peptide ligand-binding receptors View Gene Set 2.009e-08 167 4.487e-06 5 REACTOME - Peptide ligand-binding receptors gene set www.pathwaycomm...
Null Olfactory Signaling Pathway View Gene Set 7.631e-08 370 1.421e-05 6 REACTOME - Olfactory Signaling Pathway gene set www.pathwaycomm...
Null SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion View Gene Set 2.231e-05 19 0.003561 7 REACTOME - SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion gene set www.pathwaycomm...
Null Interaction between L1 and Ankyrins View Gene Set 7.853e-05 14 0.01096 8 REACTOME - Interaction between L1 and Ankyrins gene set www.pathwaycomm...
Null Cytochrome P450 - arranged by substrate type View Gene Set 0.0001367 47 0.01696 9 REACTOME - Cytochrome P450 - arranged by substrate type gene set www.pathwaycomm...
Null Na+/Cl- dependent neurotransmitter transporters View Gene Set 0.0001681 18 0.01877 10 REACTOME - Na+/Cl- dependent neurotransmitter transporters gene set www.pathwaycomm...
Null Class B/2 (Secretin family receptors) View Gene Set 0.0002005 47 0.02036 11 REACTOME - Class B/2 (Secretin family receptors) gene set www.pathwaycomm...
Null CRMPs in Sema3A signaling View Gene Set 0.0004806 16 0.04474 12 REACTOME - CRMPs in Sema3A signaling gene set www.pathwaycomm...

Gene Set Collection: mirbase.targets

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null hsa-miR-663 View Gene Set 4.176e-07 743 0.0002969 1 microRNA targets for hsa-miR-663 from mirbase.targets www.mirbase.org...
Null hsa-miR-615-5p View Gene Set 3.07e-06 848 0.0009895 2 microRNA targets for hsa-miR-615-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-886-3p View Gene Set 4.175e-06 745 0.0009895 2 microRNA targets for hsa-miR-886-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-330-5p View Gene Set 1.542e-05 728 0.002741 4 microRNA targets for hsa-miR-330-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-326 View Gene Set 2.141e-05 650 0.003044 5 microRNA targets for hsa-miR-326 from mirbase.targets www.mirbase.org...
Null hsa-miR-609 View Gene Set 3.234e-05 687 0.003832 6 microRNA targets for hsa-miR-609 from mirbase.targets www.mirbase.org...
Null hsa-miR-423-3p View Gene Set 0.0002679 741 0.02381 7 microRNA targets for hsa-miR-423-3p from mirbase.targets www.mirbase.org...
Null hsa-miR-593 View Gene Set 0.0002533 556 0.02381 7 microRNA targets for hsa-miR-593 from mirbase.targets www.mirbase.org...
Null hsa-miR-296-5p View Gene Set 0.0003257 755 0.02573 9 microRNA targets for hsa-miR-296-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-370 View Gene Set 0.0004027 710 0.02863 10 microRNA targets for hsa-miR-370 from mirbase.targets www.mirbase.org...
Null hsa-miR-571 View Gene Set 0.000491 720 0.03174 11 microRNA targets for hsa-miR-571 from mirbase.targets www.mirbase.org...
Null hsa-miR-675 View Gene Set 0.0006255 686 0.03706 12 microRNA targets for hsa-miR-675 from mirbase.targets www.mirbase.org...
Null hsa-miR-500* View Gene Set 0.0008328 538 0.03735 13 microRNA targets for hsa-miR-500* from mirbase.targets www.mirbase.org...
Null hsa-miR-565 View Gene Set 0.0008464 689 0.03735 13 microRNA targets for hsa-miR-565 from mirbase.targets www.mirbase.org...
Null hsa-miR-614 View Gene Set 0.0007558 578 0.03735 13 microRNA targets for hsa-miR-614 from mirbase.targets www.mirbase.org...
Null hsa-miR-886-5p View Gene Set 0.0008931 793 0.03735 13 microRNA targets for hsa-miR-886-5p from mirbase.targets www.mirbase.org...
Null hsa-miR-939 View Gene Set 0.0007491 667 0.03735 13 microRNA targets for hsa-miR-939 from mirbase.targets www.mirbase.org...
Null hsa-miR-639 View Gene Set 0.0009462 561 0.03738 18 microRNA targets for hsa-miR-639 from mirbase.targets www.mirbase.org...
Null hsa-miR-937 View Gene Set 0.001139 654 0.04263 19 microRNA targets for hsa-miR-937 from mirbase.targets www.mirbase.org...

Gene Set Collection: miRNAtargetUnion

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-886-3p View Gene Set 2.491e-06 1039 0.005764 1 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-886-3p from miRNAtargetUnion www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-663 View Gene Set 4.157e-05 1582 0.0481 2 microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-663 from miRNAtargetUnion www.mirbase.org...

Gene Set Collection: hprdBatch.UP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL-3 Signaling Pathway View Gene Set 0.0005039 40 0.01008 1 From NetPath for IL-3 Signaling Pathway www.netpath.org...
Null IL-4 Signaling Pathway View Gene Set 0.005371 217 0.03581 2 From NetPath for IL-4 Signaling Pathway www.netpath.org...
Null IL-9 Signaling Pathway View Gene Set 0.004786 25 0.03581 2 From NetPath for IL-9 Signaling Pathway www.netpath.org...

Gene Set Collection: hprdBatch.DIFFERENT

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL-4 Signaling Pathway View Gene Set 0.002282 301 0.04563 1 From NetPath for IL-4 Signaling Pathway www.netpath.org...
Null IL-3 Signaling Pathway View Gene Set 0.005576 49 0.04671 2 From NetPath for IL-3 Signaling Pathway www.netpath.org...
Null IL-9 Signaling Pathway View Gene Set 0.007007 26 0.04671 2 From NetPath for IL-9 Signaling Pathway www.netpath.org...

Gene Set Collection: hprdManual.UP

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL1 View Gene Set 1.903e-05 85 0.0004568 1 From NetPath for IL1 www.netpath.org...
Null TNFalpha View Gene Set 7.633e-05 113 0.0009159 2 From NetPath for TNFalpha www.netpath.org...
Null IL3 View Gene Set 0.0004881 17 0.003905 3 From NetPath for IL3 www.netpath.org...
Null IL9 View Gene Set 0.004786 25 0.02872 4 From NetPath for IL9 www.netpath.org...

Gene Set Collection: hprdManual.DOWN

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL1 View Gene Set 0.0008653 35 0.01019 1 From NetPath for IL1 www.netpath.org...
Null Leptin View Gene Set 0.001072 79 0.01019 1 From NetPath for Leptin www.netpath.org...
Null IL-7 View Gene Set 0.00363 9 0.02299 3 From NetPath for IL-7 www.netpath.org...

Gene Set Collection: hprdManual.DIFFERENT

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null IL1 View Gene Set 1.198e-07 120 2.876e-06 1 From NetPath for IL1 www.netpath.org...
Null TNFalpha View Gene Set 7.85e-05 121 0.0009421 2 From NetPath for TNFalpha www.netpath.org...
Null Leptin View Gene Set 0.0002126 110 0.001701 3 From NetPath for Leptin www.netpath.org...
Null IL3 View Gene Set 0.000472 20 0.002832 4 From NetPath for IL3 www.netpath.org...
Null IL4 View Gene Set 0.007221 269 0.02888 5 From NetPath for IL4 www.netpath.org...
Null IL9 View Gene Set 0.007007 26 0.02888 5 From NetPath for IL9 www.netpath.org...

Gene Set Collection: tfbsK3Z3

Arguments: refPop=all, featureType=ENTREZID, colname=WilcoxUP, ranks.only=TRUE, absolute=FALSE, alternative=up

Gene Set Name GeneSetDescription Value Gene Set Size Corrected Value Ranking Description URL
Null V_MEIS1AHOXA9_01 View Gene Set 7.771e-07 263 8.276e-05 1 List of genes containing a conserved (FDR < 0.1%) V$MEIS1AHOXA9_01 TFBS located within 3 kb around the TSS for the HOXA9B transcription factor www.gene-regula...
Null V_NRSF_01 View Gene Set 6.56e-07 256 8.276e-05 1 List of genes containing a conserved (FDR < 0.1%) V$NRSF_01 TFBS located within 3 kb around the TSS for the NRSF form 1 transcription factor www.gene-regula...
Null V_MEF2_02 View Gene Set 4.416e-06 157 0.0003135 3 List of genes containing a conserved (FDR < 0.1%) V$MEF2_02 TFBS located within 3 kb around the TSS for the MEF-2A transcription factor www.gene-regula...
Null V_OCT_C View Gene Set 1.291e-05 316 0.0006873 4 List of genes containing a conserved (FDR < 0.1%) V$OCT_C TFBS located within 3 kb around the TSS for the Oct-B1 transcription factor www.gene-regula...
Null V_POU3F2_02 View Gene Set 4.194e-05 261 0.001787 5 List of genes containing a conserved (FDR < 0.1%) V$POU3F2_02 TFBS located within 3 kb around the TSS for the POU3F2 transcription factor www.gene-regula...
Null V_POU3F2_01 View Gene Set 6.285e-05 324 0.002231 6 List of genes containing a conserved (FDR < 0.1%) V$POU3F2_01 TFBS located within 3 kb around the TSS for the POU3F2 transcription factor www.gene-regula...
Null V_NKX25_02 View Gene Set 7.359e-05 252 0.002239 7 List of genes containing a conserved (FDR < 0.1%) V$NKX25_02 TFBS located within 3 kb around the TSS for the Nkx2-5 transcription factor www.gene-regula...
Null V_CART1_01 View Gene Set 9.502e-05 248 0.002351 8 List of genes containing a conserved (FDR < 0.1%) V$CART1_01 TFBS located within 3 kb around the TSS for the Cart-1 transcription factor www.gene-regula...
Null V_OCT1_03 View Gene Set 9.935e-05 29 0.002351 8 List of genes containing a conserved (FDR < 0.1%) V$OCT1_03 TFBS located within 3 kb around the TSS for the POU2F1 transcription factor www.gene-regula...
Null V_CDPCR3HD_01 View Gene Set 0.0001912 100 0.003702 10 List of genes containing a conserved (FDR < 0.1%) V$CDPCR3HD_01 TFBS located within 3 kb around the TSS for the CUTL1 transcription factor www.gene-regula...
Null V_HOXA3_01 View Gene Set 0.0001892 81 0.003702 10 List of genes containing a conserved (FDR < 0.1%) V$HOXA3_01 TFBS located within 3 kb around the TSS for the HOXA3 transcription factor www.gene-regula...
Null V_STAT5B_01 View Gene Set 0.0002487 50 0.004415 12 List of genes containing a conserved (FDR < 0.1%) V$STAT5B_01 TFBS located within 3 kb around the TSS for the STAT5B transcription factor www.gene-regula...
Null V_HNF4_01 View Gene Set 0.0003134 11 0.005136 13 List of genes containing a conserved (FDR < 0.1%) V$HNF4_01 TFBS located within 3 kb around the TSS for the HNF-4alpha2 transcription factor www.gene-regula...
Null V_LHX3_01 View Gene Set 0.0004169 80 0.006343 14 List of genes containing a conserved (FDR < 0.1%) V$LHX3_01 TFBS located within 3 kb around the TSS for the LHX3a transcription factor www.gene-regula...
Null V_PAX6_01 View Gene Set 0.0004494 245 0.006382 15 List of genes containing a conserved (FDR < 0.1%) V$PAX6_01 TFBS located within 3 kb around the TSS for the Pax-6 transcription factor www.gene-regula...
Null V_NKX61_01 View Gene Set 0.0004939 186 0.006575 16 List of genes containing a conserved (FDR < 0.1%) V$NKX61_01 TFBS located within 3 kb around the TSS for the Nkx6-1 transcription factor www.gene-regula...
Null V_MEF2_03 View Gene Set 0.0007703 164 0.009651 17 List of genes containing a conserved (FDR < 0.1%) V$MEF2_03 TFBS located within 3 kb around the TSS for the MEF-2A transcription factor www.gene-regula...
Null V_MEF2_01 View Gene Set 0.0008841 385 0.009952 18 List of genes containing a conserved (FDR < 0.1%) V$MEF2_01 TFBS located within 3 kb around the TSS for the MEF-2A transcription factor www.gene-regula...
Null V_POU6F1_01 View Gene Set 0.0008878 200 0.009952 18 List of genes containing a conserved (FDR < 0.1%) V$POU6F1_01 TFBS located within 3 kb around the TSS for the POU6F1 (c2) transcription factor www.gene-regula...
Null V_EVI1_01 View Gene Set 0.001382 265 0.01472 20 List of genes containing a conserved (FDR < 0.1%) V$EVI1_01 TFBS located within 3 kb around the TSS for the Evi-1 transcription factor www.gene-regula...
Null V_NKX22_01 View Gene Set 0.001583 246 0.01554 21 List of genes containing a conserved (FDR < 0.1%) V$NKX22_01 TFBS located within 3 kb around the TSS for the Nkx2-2 transcription factor www.gene-regula...
Null V_RSRFC4_01 View Gene Set 0.001605 394 0.01554 21 List of genes containing a conserved (FDR < 0.1%) V$RSRFC4_01 TFBS located within 3 kb around the TSS for the RSRFC4 transcription factor www.gene-regula...
Null V_LUN1_01 View Gene Set 0.001787 194 0.01636 23 List of genes containing a conserved (FDR < 0.1%) V$LUN1_01 TFBS located within 3 kb around the TSS for the LUN-1 transcription factor www.gene-regula...
Null V_OCT1_07 View Gene Set 0.001843 213 0.01636 23 List of genes containing a conserved (FDR < 0.1%) V$OCT1_07 TFBS located within 3 kb around the TSS for the POU2F1 transcription factor www.gene-regula...
Null V_PBX1_02 View Gene Set 0.001981 223 0.01688 25 List of genes containing a conserved (FDR < 0.1%) V$PBX1_02 TFBS located within 3 kb around the TSS for the Pbx1a transcription factor www.gene-regula...
Null V_LMO2COM_02 View Gene Set 0.00307 138 0.02515 26 List of genes containing a conserved (FDR < 0.1%) V$LMO2COM_02 TFBS located within 3 kb around the TSS for the Lmo2 transcription factor www.gene-regula...
Null V_SEF1_C View Gene Set 0.003733 141 0.02945 27 List of genes containing a conserved (FDR < 0.1%) V$SEF1_C TFBS located within 3 kb around the TSS for the SEF-1 (1) transcription factor www.gene-regula...
Null V_CDP_02 View Gene Set 0.003884 210 0.02955 28 List of genes containing a conserved (FDR < 0.1%) V$CDP_02 TFBS located within 3 kb around the TSS for the CUTL1 transcription factor www.gene-regula...
Null V_MYB_Q6 View Gene Set 0.004251 96 0.03122 29 List of genes containing a conserved (FDR < 0.1%) V$MYB_Q6 TFBS located within 3 kb around the TSS for the c-Myb transcription factor www.gene-regula...
Null V_OCT1_04 View Gene Set 0.004758 82 0.03269 30 List of genes containing a conserved (FDR < 0.1%) V$OCT1_04 TFBS located within 3 kb around the TSS for the POU2F1 transcription factor www.gene-regula...
Null V_RFX1_02 View Gene Set 0.004679 364 0.03269 30 List of genes containing a conserved (FDR < 0.1%) V$RFX1_02 TFBS located within 3 kb around the TSS for the RFX1 transcription factor www.gene-regula...
Null V_OCT1_01 View Gene Set 0.005446 70 0.03625 32 List of genes containing a conserved (FDR < 0.1%) V$OCT1_01 TFBS located within 3 kb around the TSS for the POU2F1 transcription factor www.gene-regula...
Null V_E2F_01 View Gene Set 0.007216 94 0.04658 33 List of genes containing a conserved (FDR < 0.1%) V$E2F_01 TFBS located within 3 kb around the TSS for the E2F transcription factor www.gene-regula...
Null V_S8_01 View Gene Set 0.0076 69 0.04761 34 List of genes containing a conserved (FDR < 0.1%) V$S8_01 TFBS located within 3 kb around the TSS for the S8 transcription factor www.gene-regula...