Test Results

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Gene Set Null IL2-mediated signaling events

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10892-2.2687.945-5.3232.015e-074.092e-066.6810892MALT1mucosa associated lymphoid tissue lymphoma translocation gene 1ENSG00000172175604860
11541.0675.883.6580.00030090.002214-0.2161154CISHcytokine inducible SH2-containing proteinENSG00000114737602441, 607948, 611162, 614383
1432-1.0229.706-4.6654.667e-066.141e-053.6911432MAPK14mitogen-activated protein kinase 14ENSG00000112062600289
1540-1.9377.614-4.5647.345e-069.025e-053.2621540CYLDcylindromatosis (turban tumor syndrome)ENSG00000083799132700, 601606, 605018, 605041
18691.6576.3565.3331.922e-073.914e-066.7251869E2F1E2F transcription factor 1ENSG00000101412189971
2070.83539.2633.3290.00098130.006052-1.305207AKT1v-akt murine thymoma viral oncogene homolog 1ENSG00000142208114480, 114500, 164730, 167000, 176920, 181500, 604370
259230-1.6487.884-3.5790.00040270.002833-0.4856259230SGMS1sphingomyelin synthase 1ENSG00000198964611573
35590.84114.3654.7063.886e-065.269e-053.8643559IL2RAinterleukin 2 receptor, alphaENSG00000134460147730, 601942, 606367
3560.58244.363.2560.0012610.007479-1.534356FASLGFas ligand (TNF superfamily, member 6)ENSG00000117560134638, 152700
35601.2714.7225.6723.356e-088.964e-078.3943560IL2RBinterleukin 2 receptor, betaENSG00000100385146710
3667-1.6947.989-3.8940.00012190.0010320.62323667IRS1insulin receptor substrate 1ENSG00000169047125853, 147545
37181.0624.4314.6255.591e-067.15e-053.523718JAK3Janus kinase 3ENSG00000105639600173
3725-2.7458.139-5.6174.476e-081.138e-068.1183725JUNjun proto-oncogeneENSG00000177606165160
3845-2.1078.959-5.8751.133e-083.575e-079.4353845KRASv-Ki-ras2 Kirsten rat sarcoma viral oncogene homologENSG00000133703109800, 114480, 115150, 137215, 190070, 211980, 218040, 260350, 609942
40490.65464.2574.0416.784e-050.00061911.1714049LTAlymphotoxin alpha (TNF superfamily, member 1)ENSG00000226979, ENSG00000238130, ENSG00000226275, ENSG00000230279, ENSG00000231408, ENSG00000173503, ENSG00000223919153440, 607507, 608446, 610988
4091.7966.3064.9721.125e-061.802e-055.041409ARRB2arrestin, beta 2ENSG00000141480107941
509431.0773.9477.4321.147e-121.317e-1018.3150943FOXP3forkhead box P3ENSG00000049768222100, 300292, 304790
5578-1.3047.313-4.538.549e-060.00010283.1185578PRKCAprotein kinase C, alphaENSG00000154229176960
5590-1.0618.557-4.5039.659e-060.00011433.0035590PRKCZprotein kinase C, zetaENSG00000067606176982
55991.8624.766.7866.249e-114.216e-0914.445599MAPK8mitogen-activated protein kinase 8ENSG00000107643601158
5601-0.8149.1-3.3410.00094080.005836-1.2665601MAPK9mitogen-activated protein kinase 9ENSG00000050748602896
5960.71754.1594.2393.005e-050.00030751.934596BCL2B-cell CLL/lymphoma 2ENSG00000171791151430
6198-2.6828.553-6.2011.879e-097.681e-0811.166198RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1ENSG00000108443608938
6654-2.2168.464-6.631.584e-109.237e-0913.546654SOS1son of sevenless homolog 1 (Drosophila)ENSG00000115904135300, 163955, 182530, 610733
67140.62014.2283.6330.00032960.002391-0.30046714SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)ENSG00000197122190090
6772-2.2018.853-4.6325.425e-066.962e-053.5486772STAT1signal transducer and activator of transcription 1, 91kDaENSG00000115415209950, 600555, 613796, 614162
67761.0164.8093.2990.0010880.006588-1.46776STAT5Asignal transducer and activator of transcription 5AENSG00000126561601511
67771.3664.5835.6962.955e-088.068e-078.5166777STAT5Bsignal transducer and activator of transcription 5BENSG00000173757245590, 604260
7323-0.493110.44-4.4111.442e-050.0001622.6257323UBE2D3ubiquitin-conjugating enzyme E2D 3ENSG00000109332602963
8027-2.4398.393-8.3053.583e-151.038e-1223.98027STAMsignal transducing adaptor molecule (SH3 domain and ITAM motif) 1ENSG00000136738601899
8081.4319.5063.7080.00024930.001889-0.04157808CALM3calmodulin 3 (phosphorylase kinase, delta)ENSG00000143933, ENSG00000160014, ENSG00000198668114183
85171.1477.0423.9380.00010240.00088590.78568517IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gammaENSG00000073009300248, 300291, 300301, 300584, 300636, 300640, 308300
8661-0.9357.392-4.1234.863e-050.00046491.4838661EIF3Aeukaryotic translation initiation factor 3, subunit AENSG00000107581602039
890-1.6528.752-5.7292.484e-087.013e-078.683890CCNA2cyclin A2ENSG00000145386123835
89451.0445.3123.5890.00038830.002745-0.4528945BTRCbeta-transducin repeat containing E3 ubiquitin protein ligaseENSG00000166167603482
90211.974.696.5123.169e-101.657e-0812.889021SOCS3suppressor of cytokine signaling 3ENSG00000184557604176, 605805
90460.98414.5915.1814.09e-077.461e-066.0049046DOK2docking protein 2, 56kDaENSG00000147443604997
92611.4376.2243.6750.0002820.0021-0.15619261MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2ENSG00000162889602006