Test Results

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Gene Set Broad MARKEY_RB1_ACUTE_LOF_DN

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10000.74219.8185.4759.324e-088.01e-076.8721000CDH2cadherin 2, type 1, N-cadherin (neuronal)ENSG00000170558114020
10112-1.1489.128-11.13.416e-241.538e-2244.1110112KIF20Akinesin family member 20AENSG00000112984605664
10236-0.408811.43-7.7161.843e-133.067e-1219.7110236HNRNPRheterogeneous nuclear ribonucleoprotein RENSG00000125944607201
1058-1.34710.5-17.682.774e-481.03e-4599.151058CENPAcentromere protein AENSG00000115163117139
10592-0.8158.358-8.1937.667e-151.467e-1322.8410592SMC2structural maintenance of chromosomes 2ENSG00000136824605576
10635-0.68179.155-4.4959.967e-066.353e-052.37110635RAD51AP1RAD51 associated protein 1ENSG00000111247603070
10771-0.69369.874-12.755.457e-304.251e-2857.3410771ZMYND11zinc finger, MYND-type containing 11ENSG00000259741, ENSG00000015171608668
110340.282411.683.9569.543e-050.00051530.222411034DSTNdestrin (actin depolymerizing factor)ENSG00000125868609114
11073-0.5689.347-5.7941.751e-081.656e-078.49511073TOPBP1topoisomerase (DNA) II binding protein 1ENSG00000163781607760
111680.52178.1744.7143.736e-062.539e-053.31111168PSIP1PC4 and SFRS1 interacting protein 1ENSG00000164985603620
1434-0.351711.41-6.3269.244e-101.028e-0811.361434CSE1LCSE1 chromosome segregation 1-like (yeast)ENSG00000124207601342
1728-0.459110.28-6.4923.562e-104.157e-0912.291728NQO1NAD(P)H dehydrogenase, quinone 1ENSG00000181019125860
1894-0.416810.08-6.1222.929e-093.097e-0810.241894ECT2epithelial cell transforming sequence 2 oncogeneENSG00000114346600586
2100.78287.3227.3342.143e-123.193e-1117.3210ALADaminolevulinate dehydrataseENSG00000148218125270, 612740
23234-0.347112.4-6.2141.745e-091.883e-0810.7423234DNAJC9DnaJ (Hsp40) homolog, subfamily C, member 9ENSG00000213551611206
258000.5548.6874.7852.702e-061.879e-053.62225800SLC39A6solute carrier family 39 (zinc transporter), member 6ENSG00000141424608731
25804-0.273210.18-4.4621.154e-057.279e-052.23125804LSM4LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)ENSG00000130520607284
25836-1.4037.888-12.391.058e-287.081e-2754.425836NIPBLNipped-B homolog (Drosophila)ENSG00000164190122470, 608667
259760.517210.124.7962.571e-061.796e-053.6725976TIPARPTCDD-inducible poly(ADP-ribose) polymeraseENSG00000163659612480
26586-0.31829.796-4.5238.835e-065.667e-052.48726586CKAP2cytoskeleton associated protein 2ENSG00000136108611569
27290.55858.1657.6742.425e-133.977e-1219.442729GCLCglutamate-cysteine ligase, catalytic subunitENSG00000001084230450, 606857, 608446
27316-0.488210.9-9.2584.327e-181.104e-1630.2127316RBMXRNA binding motif protein, X-linkedENSG00000147274300199
29127-0.566210.71-11.644.944e-262.629e-2448.3129127RACGAP1Rac GTPase activating protein 1ENSG00000161800604980
3149-0.71289.851-8.5566.366e-161.348e-1425.293149HMGB3high mobility group box 3ENSG00000029993300193
3151-0.134613.2-4.8252.242e-061.577e-053.8023151HMGN2high mobility group nucleosomal binding domain 2ENSG00000198830163910
332-0.39989.831-7.2623.367e-124.915e-1116.86332BIRC5baculoviral IAP repeat containing 5ENSG00000089685603352
3609-0.64639.001-9.1628.667e-182.179e-1629.533609ILF3interleukin enhancer binding factor 3, 90kDaENSG00000129351603182
372-0.351310.62-5.7562.145e-082.003e-078.298372ARCN1archain 1ENSG00000095139600820
37960.49598.5125.9646.993e-096.982e-089.3883796KIF2Akinesin heavy chain member 2AENSG00000068796602591
3835-0.80756.491-6.883.554e-114.633e-1014.553835KIF22kinesin family member 22ENSG00000079616603213, 603546
3843-0.228310.99-4.2383.008e-050.00017671.3183843IPO5importin 5ENSG00000065150602008
4173-1.057.722-8.3093.497e-156.919e-1423.614173MCM4minichromosome maintenance complex component 4ENSG00000104738602638
4174-0.57469.193-7.2224.338e-126.247e-1116.614174MCM5minichromosome maintenance complex component 5ENSG00000100297602696
4176-0.403510.86-6.8015.739e-117.285e-1014.084176MCM7minichromosome maintenance complex component 7ENSG00000166508600592
4288-0.89369.259-15.61.77e-403.553e-3881.314288MKI67antigen identified by monoclonal antibody Ki-67ENSG00000148773176741
51053-0.365810.54-4.2023.51e-050.00020341.17151053GMNNgeminin, DNA replication inhibitorENSG00000112312602842
5111-0.240411.68-5.1315.218e-074.025e-065.2065111PCNAproliferating cell nuclear antigenENSG00000132646176740
51203-0.166911.22-3.9928.269e-050.00045150.35851203NUSAP1nucleolar and spindle associated protein 1ENSG00000137804612818
51322-0.61729.379-11.597.357e-263.79e-2447.9151322WACWW domain containing adaptor with coiled-coilENSG00000095787NA
5347-1.4898.164-13.864.891e-345.53e-3266.595347PLK1polo-like kinase 1ENSG00000166851602098
54726-0.98619.139-11.172.082e-249.486e-2344.654726OTUD4OTU domain containing 4ENSG00000164164611744
54780-0.58918.639-4.9961e-067.376e-064.57954780NSMCE4Anon-SMC element 4 homolog A (S. cerevisiae)ENSG00000107672612987
54962-0.71228.626-4.9031.56e-061.119e-054.1554962TIPINTIMELESS interacting proteinENSG00000075131610716
5557-0.47349.395-6.4195.419e-106.194e-0911.885557PRIM1primase, DNA, polypeptide 1 (49kDa)ENSG00000198056176635
56252-0.55128.536-4.3411.946e-050.00011821.73356252YLPM1YLP motif containing 1ENSG00000119596NA
57341.7238.30410.321.597e-215.721e-2038.035734PTGER4prostaglandin E receptor 4 (subtype EP4)ENSG00000171522601586
5885-0.469911.07-6.425.38e-106.152e-0911.895885RAD21RAD21 homolog (S. pombe)ENSG00000164754606462
5933-0.53716.7-4.4451.245e-057.817e-052.1595933RBL1retinoblastoma-like 1 (p107)ENSG00000080839116957
5984-0.450910.5-5.1494.78e-073.725e-065.2915984RFC4replication factor C (activator 1) 4, 37kDaENSG00000163918102577
6421-0.246310.77-4.0366.927e-050.00038290.52576421SFPQsplicing factor proline/glutamine-richENSG00000116560605199
64710-0.395612.02-5.3441.812e-071.5e-066.22964710NUCKS1nuclear casein kinase and cyclin-dependent kinase substrate 1ENSG00000069275611912
65580.90378.1857.5724.677e-137.395e-1218.796558SLC12A2solute carrier family 12 (sodium/potassium/chloride transporters), member 2ENSG00000064651600840
672-0.45747.28-4.6774.437e-062.984e-053.146672BRCA1breast cancer 1, early onsetENSG00000012048113705, 114480, 604370, 614320
6790-1.3959.873-19.081.642e-538.711e-51111.16790AURKAaurora kinase AENSG00000087586114500, 603072
7027-0.361110.46-5.8721.152e-081.117e-078.9027027TFDP1transcription factor Dp-1ENSG00000198176189902
7112-1.1659.166-13.846.037e-346.759e-3266.387112TMPOthymopoietinENSG00000120802188380, 613740
7514-0.712111.74-17.567.92e-482.846e-4598.117514XPO1exportin 1 (CRM1 homolog, yeast)ENSG00000082898602559
7866-0.34059.745-4.73.986e-062.7e-053.2497866IFRD2interferon-related developmental regulator 2ENSG00000214706602725
7913-0.512811.72-9.1271.111e-172.761e-1629.287913DEKDEK oncogeneENSG00000124795125264
79733-1.5177.63-8.8995.705e-171.338e-1527.6779733E2F8E2F transcription factor 8ENSG00000129173612047
8091-3.9479.054-34.584.125e-1069.19e-102230.98091HMGA2high mobility group AT-hook 2ENSG00000149948150699, 151900, 600698, 611547
83461-0.827.988-5.8831.084e-081.054e-078.96283461CDCA3cell division cycle associated 3ENSG00000111665607749
88480.609611.168.8061.101e-162.517e-1527.028848TSC22D1TSC22 domain family, member 1ENSG00000102804607715
8880-0.39357.776-4.1733.949e-050.0002271.0598880FUBP1far upstream element (FUSE) binding protein 1ENSG00000162613603444
890-0.8138.733-9.9991.772e-205.647e-1935.65890CCNA2cyclin A2ENSG00000145386123835
891-0.757310.69-15.012.892e-384.808e-3676.25891CCNB1cyclin B1ENSG00000134057123836
90261.0356.8969.6891.819e-195.264e-1833.359026HIP1Rhuntingtin interacting protein 1 relatedENSG00000130787605613
9055-0.72110.19-12.621.627e-291.208e-2756.269055PRC1protein regulator of cytokinesis 1ENSG00000198901603484
9126-0.54499.068-5.1385.034e-073.902e-065.2419126SMC3structural maintenance of chromosomes 3ENSG00000108055606062, 610759
9133-0.92510.23-14.261.667e-352.185e-3369.949133CCNB2cyclin B2ENSG00000157456602755
9319-0.2589.898-6.972.059e-112.746e-1015.089319TRIP13thyroid hormone receptor interactor 13ENSG00000071539604507
9493-0.70748.468-6.883.55e-114.631e-1014.559493KIF23kinesin family member 23ENSG00000137807605064
9900.71977.7796.0823.649e-093.796e-0810.02990CDC6cell division cycle 6 homolog (S. cerevisiae)ENSG00000094804602627, 613805
995-0.71896.837-8.3372.886e-155.776e-1423.8995CDC25Ccell division cycle 25 homolog C (S. pombe)ENSG00000158402157680