Test Results

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Gene Set Null Class I PI3K signaling events

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10066-0.46338.306-2.0780.038530.6951-3.75910066SCAMP2secretory carrier membrane protein 2ENSG00000140497606912
10163-0.49498.577-2.3170.021160.5884-3.30410163WASF2WAS protein family, member 2ENSG00000158195605875
10524-0.49467.19-2.6940.0074520.469-2.49210524KAT5K(lysine) acetyltransferase 5ENSG00000172977601409
10580-0.27174.473-2.3180.021130.5884-3.30310580SORBS1sorbin and SH3 domain containing 1ENSG00000095637605264
110330.44596.4092.0660.039660.703-3.7811033ADAP1ArfGAP with dual PH domains 1ENSG00000105963608114
1211-0.304911.69-2.6080.0095690.517-2.6891211CLTAclathrin, light chain AENSG00000122705118960
1387-0.52988.584-2.1650.031170.6683-3.5991387CREBBPCREB binding proteinENSG00000005339180849, 600140
1398-0.33049.42-2.4270.015810.5763-3.081398CRKv-crk sarcoma virus CT10 oncogene homolog (avian)ENSG00000167193164762
1445-0.5148.287-2.1650.031150.6683-3.5991445CSKc-src tyrosine kinaseENSG00000103653124095
1452-0.259511.39-2.40.017030.5769-3.1371452CSNK1A1casein kinase 1, alpha 1ENSG00000113712600505
1453-0.34569.618-3.1120.0020390.3049-1.4581453CSNK1Dcasein kinase 1, deltaENSG00000141551600864
14621.6426.1822.1590.031620.6708-3.611462VCANversicanENSG00000038427118661, 143200
16061.064.8073.9140.00011270.089680.90981606DGKAdiacylglycerol kinase, alpha 80kDaENSG00000065357125855
1740.2013.9622.2360.026070.6334-3.464174AFPalpha-fetoproteinENSG00000081051104150
1847-0.73848.872-1.7390.08310.8041-4.3221847DUSP5dual specificity phosphatase 5ENSG00000138166603069
1975-0.399510.61-2.3320.020380.5843-3.2761975EIF4Beukaryotic translation initiation factor 4BENSG00000063046603928
1977-0.43259.441-1.8150.07060.7776-4.2041977EIF4Eeukaryotic translation initiation factor 4EENSG00000151247133440
2017-0.43444.578-2.140.033150.679-3.6462017CTTNcortactinENSG00000085733164765
2033-0.44147.683-1.8060.071990.7819-4.2192033EP300E1A binding protein p300ENSG00000100393114500, 180849, 602700, 613684
22680.24074.2921.8320.067970.7746-4.1772268FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homologENSG00000000938164940
22943-0.237413.09-2.0730.039040.6991-3.76822943DKK1dickkopf 1 homolog (Xenopus laevis)ENSG00000107984605189
230850.52536.3012.2940.022470.5974-3.3523085ERC1ELKS/RAB6-interacting/CAST family member 1ENSG00000082805607127
23163-0.45088.317-2.460.014450.552-3.0123163GGA3golgi-associated, gamma adaptin ear containing, ARF binding protein 3ENSG00000125447606006
233030.60346.5992.6650.0081280.4868-2.5623303KIF13Bkinesin family member 13BENSG00000197892607350
234330.35259.312.0330.042920.7088-3.83923433RHOQras homolog family member QENSG00000119729605857
25-0.498.128-2.9970.0029570.3425-1.75725ABL1c-abl oncogene 1, non-receptor tyrosine kinaseENSG00000097007189980
25340.77918.7253.5320.00047820.1754-0.27922534FYNFYN oncogene related to SRC, FGR, YESENSG00000010810137025
2767-0.42939.842-2.2010.02850.6545-3.5322767GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)ENSG00000088256139313
27760.55366.1292.0780.038580.6954-3.762776GNAQguanine nucleotide binding protein (G protein), q polypeptideENSG00000156052600998
289840.48785.1362.2630.024370.6225-3.41228984RGCCregulator of cell cycleENSG00000102760610077
291080.62546.3212.4440.015110.5641-3.04529108PYCARDPYD and CARD domain containingENSG00000103490606838
3320-0.130513.71-1.7140.087570.8148-4.3593320HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 1ENSG00000080824140571
3551.4265.3963.8220.00016150.10.6129355FASFas (TNF receptor superfamily, member 6)ENSG00000026103134637, 601859
3551-0.31896.848-2.0250.043810.7101-3.8553551IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase betaENSG00000104365603258
35610.2554.6851.9140.056610.7498-4.0443561IL2RGinterleukin 2 receptor, gammaENSG00000147168300400, 308380, 312863
36740.22713.9591.8510.065140.7679-4.1463674ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)ENSG00000005961273800, 607759
36900.17024.091.7250.085650.8095-4.3433690ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)ENSG00000259753, ENSG00000259207173470, 273800, 608446
36950.30834.5561.9190.055890.7489-4.0343695ITGB7integrin, beta 7ENSG00000139626147559
37170.33884.481.9140.056640.7498-4.0443717JAK2Janus kinase 2ENSG00000096968147796, 187950, 254450, 263300, 600880, 601626
3836-0.394210.28-2.4430.015140.5641-3.0463836KPNA1karyopherin alpha 1 (importin alpha 5)ENSG00000114030600686
3837-0.303211.65-2.6540.0083920.4932-2.5863837KPNB1karyopherin (importin) beta 1ENSG00000108424602738
38450.42379.3882.1140.035320.6837-3.6933845KRASv-Ki-ras2 Kirsten rat sarcoma viral oncogene homologENSG00000133703109800, 114480, 115150, 137215, 190070, 211980, 218040, 260350, 609942
40670.5516.7441.8030.072430.7838-4.2234067LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homologENSG00000254087165120
4170-0.447110.91-3.4770.0005820.1907-0.43994170MCL1myeloid cell leukemia sequence 1 (BCL2-related)ENSG00000143384159552
42170.58045.0082.3350.020230.5842-3.274217MAP3K5mitogen-activated protein kinase kinase kinase 5ENSG00000197442602448
43030.28394.9161.7270.085210.8088-4.3394303FOXO4forkhead box O4ENSG00000184481300033
46020.75464.9513.3640.00087050.2197-0.76834602MYBv-myb myeloblastosis viral oncogene homolog (avian)ENSG00000118513189990
4800-0.34667.811-1.870.06250.764-4.1164800NFYAnuclear transcription factor Y, alphaENSG00000001167189903
4802-0.87627.396-3.9479.903e-050.088241.0174802NFYCnuclear transcription factor Y, gammaENSG00000066136605344
4988-0.18634.014-2.2010.028480.6545-3.5314988OPRM1opioid receptor, mu 1ENSG00000112038600018, 600669
508550.55696.042.6890.0075770.4716-2.50550855PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)ENSG00000102981607484
5347-0.49158.164-2.1180.034990.6832-3.6865347PLK1polo-like kinase 1ENSG00000166851602098
54487-0.36766.363-1.7080.088770.815-4.36954487DGCR8DiGeorge syndrome critical region gene 8ENSG00000128191609030
5452-0.19144.125-1.8150.070520.7776-4.2045452POU2F2POU class 2 homeobox 2ENSG00000028277164176
54570.21414.0771.7340.083970.8063-4.3295457POU4F1POU class 4 homeobox 1ENSG00000152192601632
55240-0.50898.142-2.40.0170.5769-3.13655240STEAP3STEAP family member 3, metalloreductaseENSG00000115107609671
5532-0.261810.9-2.7550.0062360.456-2.3515532PPP3CBprotein phosphatase 3, catalytic subunit, beta isozymeENSG00000107758114106
55800.52237.4782.1090.035790.684-3.7035580PRKCDprotein kinase C, deltaENSG00000163932176977
55830.69858.5553.2970.0010950.2415-0.95475583PRKCHprotein kinase C, etaENSG00000027075601367, 605437
5591-0.3739.881-2.2480.025340.6322-3.4425591PRKDCprotein kinase, DNA-activated, catalytic polypeptideENSG00000253729600899
5771-0.408410.27-2.1250.03440.6807-3.6745771PTPN2protein tyrosine phosphatase, non-receptor type 2ENSG00000175354176887
58190.37536.561.730.084620.8076-4.3355819PVRL2poliovirus receptor-related 2 (herpesvirus entry mediator B)ENSG00000130202600798
5879-0.204912.69-1.7570.079890.7953-4.2935879RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)ENSG00000136238602048
58990.68037.7382.080.038370.6944-3.7565899RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)ENSG00000144118179551
5970-0.43129.353-2.5920.010.5229-2.7235970RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)ENSG00000173039164014
598-0.50879.808-2.3460.019650.5814-3.248598BCL2L1BCL2-like 1ENSG00000171552600039
6249-0.38928.836-2.2080.0280.6532-3.5186249CLIP1CAP-GLY domain containing linker protein 1ENSG00000130779179838
63970-0.22393.944-2.1230.034570.6807-3.67763970TP53AIP1tumor protein p53 regulated apoptosis inducing protein 1ENSG00000120471605426
640-0.28874.246-1.8140.070760.7784-4.206640BLKB lymphoid tyrosine kinaseENSG00000136573191305, 613375
6597-0.42939.959-2.8660.0044550.4101-2.0846597SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4ENSG00000127616603254, 613325
664-0.428911.29-1.9510.051960.7291-3.981664BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3ENSG00000176171603293
67780.58537.132.2450.025480.6334-3.4466778STAT6signal transducer and activator of transcription 6, interleukin-4 inducedENSG00000166888601512
68100.3428.5322.0030.046050.7213-3.8926810STX4syntaxin 4ENSG00000103496186591
68500.48685.4282.2110.027780.6504-3.5126850SYKspleen tyrosine kinaseENSG00000165025600085
68900.5177.861.9840.048150.722-3.9256890TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)ENSG00000227816, ENSG00000168394, ENSG00000206297, ENSG00000224212, ENSG00000232367, ENSG00000226173, ENSG00000230705, ENSG00000224748170260, 604571
7027-0.252210.46-1.8980.058620.7566-4.0697027TFDP1transcription factor Dp-1ENSG00000198176189902
7091-0.29174.44-2.0190.044350.7134-3.8647091TLE4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)ENSG00000106829605132
71240.21684.1121.9530.051740.7286-3.9787124TNFtumor necrosis factorENSG00000228978, ENSG00000232810, ENSG00000204490, ENSG00000223952, ENSG00000230108, ENSG00000228321, ENSG00000206439, ENSG00000228849157300, 191160, 248310, 600807, 611162
7253-0.19553.956-1.9540.051690.7286-3.9777253TSHRthyroid stimulating hormone receptorENSG00000165409603372, 603373, 609152
7323-0.229211.27-2.4770.013820.5461-2.9767323UBE2D3ubiquitin-conjugating enzyme E2D 3ENSG00000109332602963
7514-0.158511.74-1.8090.071440.7793-4.2137514XPO1exportin 1 (CRM1 homolog, yeast)ENSG00000082898602559
8021-0.41677.102-2.0510.041140.703-3.8088021NUP214nucleoporin 214kDaENSG00000126883114350, 601626
8061-0.604111.23-2.5360.011720.5441-2.8488061FOSL1FOS-like antigen 1ENSG00000175592136515
808-0.4659.506-1.7520.080740.7979-4.301808CALM3calmodulin 3 (phosphorylase kinase, delta)ENSG00000143933, ENSG00000160014, ENSG00000198668114183
818-0.59616.628-1.7410.082780.8035-4.319818CAMK2Gcalcium/calmodulin-dependent protein kinase II gammaENSG00000148660602123
8420.63356.242.260.024540.624-3.418842CASP9caspase 9, apoptosis-related cysteine peptidaseENSG00000132906602234
84271-0.48238.157-2.4190.016150.5763-3.09784271POLDIP3polymerase (DNA-directed), delta interacting protein 3ENSG00000100227611520
8470.60388.2651.870.06240.764-4.115847CATcatalaseENSG00000121691115500, 614097
8517-0.37417.042-1.8670.062890.764-4.1218517IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gammaENSG00000073009300248, 300291, 300301, 300584, 300636, 300640, 308300
8554-0.3526.197-2.0430.041890.7053-3.8218554PIAS1protein inhibitor of activated STAT, 1ENSG00000033800603566
87-0.309912.17-2.150.032390.6724-3.62887ACTN1actinin, alpha 1ENSG00000072110102575
87670.351110.412.9990.0029370.3425-1.7518767RIPK2receptor-interacting serine-threonine kinase 2ENSG00000104312603455
8793-0.21424.27-1.7150.087450.814-4.3588793TNFRSF10Dtumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domainENSG00000173530603614
890-0.34318.752-1.7290.084760.8076-4.336890CCNA2cyclin A2ENSG00000145386123835
9000.287810.712.7340.0066370.4581-2.401900CCNG1cyclin G1ENSG00000113328601578
9020-0.71246.496-2.190.029330.6609-3.5539020MAP3K14mitogen-activated protein kinase kinase kinase 14ENSG00000006062604655
93220.55747.5451.9250.05520.7453-4.0259322TRIP10thyroid hormone receptor interactor 10ENSG00000125733604504
9448-0.40679.571-1.7790.076250.7888-4.269448MAP4K4mitogen-activated protein kinase kinase kinase kinase 4ENSG00000071054604666
94670.42659.3722.0480.041450.7041-3.8139467SH3BP5SH3-domain binding protein 5 (BTK-associated)ENSG00000131370605612
9518-0.1513.819-1.7510.080980.7979-4.3039518GDF15growth differentiation factor 15ENSG00000130513605312