Test Results

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Gene Set Null TCR signaling in naïve CD4+ T cells

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10125-0.1594.035-1.4780.14030.9609-4.41510125RASGRP1RAS guanyl releasing protein 1 (calcium and DAG-regulated)ENSG00000172575603962
102350.20164.2111.4620.14480.9609-4.42510235RASGRP2RAS guanyl releasing protein 2 (calcium and DAG-regulated)ENSG00000068831605577
13900.38578.8132.0890.037560.9609-3.9891390CREMcAMP responsive element modulatorENSG00000095794123812
1398-0.27379.42-2.0110.045270.9609-4.0521398CRKv-crk sarcoma virus CT10 oncogene homolog (avian)ENSG00000167193164762
1399-0.29689.256-1.9170.056240.9609-4.1241399CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-likeENSG00000099942602007
14320.56886.9351.9680.050020.9609-4.0851432MAPK14mitogen-activated protein kinase 14ENSG00000112062600289
14370.40144.3752.420.016120.9609-3.71437CSF2colony stimulating factor 2 (granulocyte-macrophage)ENSG00000164400138960
1445-0.50158.287-2.1130.035470.9609-3.971445CSKc-src tyrosine kinaseENSG00000103653124095
1540-0.47496.162-1.9890.047660.9609-4.0691540CYLDcylindromatosis (turban tumor syndrome)ENSG00000083799132700, 601606, 605018, 605041
18270.13773.7731.4360.1520.9609-4.441827RCAN1regulator of calcineurin 1ENSG00000159200602917
2002-0.35899.022-1.8410.066550.9609-4.1792002ELK1ELK1, member of ETS oncogene familyENSG00000126767311040
207-0.28259.263-1.6370.10260.9609-4.318207AKT1v-akt murine thymoma viral oncogene homolog 1ENSG00000142208114480, 114500, 164730, 167000, 176920, 181500, 604370
23523-0.59056.137-2.7080.0071640.9609-3.41623523CABIN1calcineurin binding protein 1ENSG00000099991604251
23530.39884.8732.1860.029590.9609-3.9092353FOSFBJ murine osteosarcoma viral oncogene homologENSG00000170345164810
27347-0.25619.122-1.7520.080860.9609-4.24227347STK39serine threonine kinase 39ENSG00000198648607648
3265-0.41518.995-2.1540.032080.9609-3.9363265HRASv-Ha-ras Harvey rat sarcoma viral oncogene homologENSG00000174775109800, 188470, 190020, 218040
35510.21534.3551.5940.11210.9609-4.3463551IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase betaENSG00000104365603258
3558-0.52014.72-1.4810.13970.9609-4.4143558IL2interleukin 2ENSG00000109471147680
3565-0.15073.905-1.5320.12660.9609-4.3843565IL4interleukin 4ENSG00000113520147780
4214-0.44744.64-1.6930.091440.9609-4.2814214MAP3K1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligaseENSG00000095015600982, 613762
4720.97236.441.7640.078760.9609-4.234472ATMataxia telangiectasia mutatedENSG00000149311114480, 208900, 607585
555030.19144.5541.3990.16280.9609-4.4655503TRPV6transient receptor potential cation channel, subfamily V, member 6ENSG00000165125606680
5566-0.27379.549-1.6540.099210.9609-4.3075566PRKACAprotein kinase, cAMP-dependent, catalytic, alphaENSG00000072062601639
55880.29384.3752.0130.045040.9609-4.055588PRKCQprotein kinase C, thetaENSG00000065675600448
5594-0.18929.713-1.740.082830.9609-4.255594MAPK1mitogen-activated protein kinase 1ENSG00000100030176948
5728-0.43224.498-1.9020.058140.9609-4.1355728PTENphosphatase and tensin homologENSG00000171862137800, 153480, 155600, 158350, 174900, 176807, 176920, 188470, 275355, 276950, 601728, 605309, 607174, 608089, 612242, 613028
57810.34234.7631.5020.1340.9609-4.4015781PTPN11protein tyrosine phosphatase, non-receptor type 11ENSG00000179295151100, 156250, 163950, 163955, 176876, 607785
5788-0.38784.328-2.0570.040580.9609-4.0155788PTPRCprotein tyrosine phosphatase, receptor type, CENSG00000081237126200, 151460, 608971, 609532
59660.28684.112.0030.046120.9609-4.0585966RELv-rel reticuloendotheliosis viral oncogene homolog (avian)ENSG00000162924164910
5970-0.50559.353-3.0390.0025840.9609-3.0545970RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)ENSG00000173039164014
64160.57878.0912.0590.040410.9609-4.0146416MAP2K4mitogen-activated protein kinase kinase 4ENSG00000065559601335
6452-0.45275.013-1.6360.10290.9609-4.3196452SH3BP2SH3-domain binding protein 2ENSG00000087266118400, 602104
66540.32376.1631.3880.16620.9609-4.4666654SOS1son of sevenless homolog 1 (Drosophila)ENSG00000115904135300, 163955, 182530, 610733
71240.20554.1121.8510.065190.9609-4.1727124TNFtumor necrosis factorENSG00000228978, ENSG00000232810, ENSG00000204490, ENSG00000223952, ENSG00000230108, ENSG00000228321, ENSG00000206439, ENSG00000228849157300, 191160, 248310, 600807, 611162
7323-0.137511.27-1.4860.13830.9609-4.4117323UBE2D3ubiquitin-conjugating enzyme E2D 3ENSG00000109332602963
7454-0.26454.317-1.9240.055290.9609-4.1187454WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)ENSG00000015285300299, 300392, 301000, 313900
7514-0.208711.74-2.3810.017880.9609-3.7367514XPO1exportin 1 (CRM1 homolog, yeast)ENSG00000082898602559
801-0.360811.46-1.9070.057440.9609-4.131801CALM1calmodulin 1 (phosphorylase kinase, delta)ENSG00000143933, ENSG00000160014, ENSG00000198668114180
8061-0.558811.23-2.3460.019640.9609-3.7688061FOSL1FOS-like antigen 1ENSG00000175592136515
808-0.63889.506-2.4070.016680.9609-3.712808CALM3calmodulin 3 (phosphorylase kinase, delta)ENSG00000143933, ENSG00000160014, ENSG00000198668114183
87670.204510.411.7470.081660.9609-4.2458767RIPK2receptor-interacting serine-threonine kinase 2ENSG00000104312603455
89450.26784.7511.4360.1520.9609-4.448945BTRCbeta-transducin repeat containing E3 ubiquitin protein ligaseENSG00000166167603482
9020-0.4846.496-1.4880.13790.9609-4.419020MAP3K14mitogen-activated protein kinase kinase kinase 14ENSG00000006062604655
940-0.21973.875-2.360.018910.9609-3.755940CD28CD28 moleculeENSG00000178562186760
9410.27294.2711.9790.048730.9609-4.076941CD80CD80 moleculeENSG00000121594112203
9420.11273.851.4940.13630.9609-4.406942CD86CD86 moleculeENSG00000114013601020
98460.27816.441.3920.16510.9609-4.4649846GAB2GRB2-associated binding protein 2ENSG00000033327606203