Test Results

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Gene Set Null Regulation of RhoA activity

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10093-0.33479.258-2.1090.03580.9609-3.97310093ARPC4actin related protein 2/3 complex, subunit 4, 20kDaENSG00000241553604226
100940.260511.361.6380.10250.9609-4.31810094ARPC3actin related protein 2/3 complex, subunit 3, 21kDaENSG00000111229604225
10163-0.52088.577-2.4380.015340.9609-3.68310163WASF2WAS protein family, member 2ENSG00000158195605875
10395-0.28854.195-2.1980.028740.9609-3.89910395DLC1deleted in liver cancer 1ENSG00000164741604258
10458-0.22374.395-1.7780.076490.9609-4.22410458BAIAP2BAI1-associated protein 2ENSG00000175866605475
105240.42917.0721.7620.079120.9609-4.23510524KAT5K(lysine) acetyltransferase 5ENSG00000172977601409
1072-0.175313.84-2.2550.024850.9609-3.8491072CFL1cofilin 1 (non-muscle)ENSG00000172757601442
1124-0.16674.05-1.640.1020.9609-4.3161124CHN2chimerin (chimaerin) 2ENSG00000106069602857
1398-0.27379.42-2.0110.045270.9609-4.0521398CRKv-crk sarcoma virus CT10 oncogene homolog (avian)ENSG00000167193164762
14320.56886.9351.9680.050020.9609-4.0851432MAPK14mitogen-activated protein kinase 14ENSG00000112062600289
1495-0.3174.364-1.8840.060580.9609-4.1481495CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDaENSG00000044115116805
15360.22434.2611.5770.11580.9609-4.3561536CYBBcytochrome b-245, beta polypeptideENSG00000165168300481, 300645, 306400
1729-0.40628.661-2.3680.018520.9609-3.7481729DIAPH1diaphanous homolog 1 (Drosophila)ENSG00000131504124900, 602121
1847-0.71118.872-1.6740.095090.9609-4.2941847DUSP5dual specificity phosphatase 5ENSG00000138166603069
2033-0.53327.683-2.1810.029970.9609-3.9132033EP300E1A binding protein p300ENSG00000100393114500, 180849, 602700, 613684
233650.157410.321.5680.1180.9609-4.36223365ARHGEF12Rho guanine nucleotide exchange factor (GEF) 12ENSG00000196914601626, 604763
23396-0.36877.272-1.5990.11090.9609-4.34323396PIP5K1Cphosphatidylinositol-4-phosphate 5-kinase, type I, gammaENSG00000186111606102, 611369
23530.39884.8732.1860.029590.9609-3.9092353FOSFBJ murine osteosarcoma viral oncogene homologENSG00000170345164810
27035-0.264.276-1.9730.04940.9609-4.08127035NOX1NADPH oxidase 1ENSG00000007952300225
290.41975.1121.5610.11950.9609-4.36629ABRactive BCR-relatedENSG00000159842155255, 600365
3727-0.3599.555-1.8320.067890.9609-4.1853727JUNDjun D proto-oncogeneENSG00000130522165162
394-0.37597.787-1.7450.081990.9609-4.246394ARHGAP5Rho GTPase activating protein 5ENSG00000100852602680
3950.26444.6021.5440.12370.9609-4.377395ARHGAP6Rho GTPase activating protein 6ENSG00000047648300118
396-0.60799.53-2.3930.017350.9609-3.725396ARHGDIARho GDP dissociation inhibitor (GDI) alphaENSG00000141522601925
3980.33864.3632.7330.0066490.9609-3.39398ARHGDIGRho GDP dissociation inhibitor (GDI) gammaENSG00000242173602844
39850.2364.3291.6810.093740.9609-4.2893985LIMK2LIM domain kinase 2ENSG00000182541601988
41680.1423.7961.6160.10720.9609-4.3324168MCF2MCF.2 cell line derived transforming sequenceENSG00000101977311030
4214-0.44744.64-1.6930.091440.9609-4.2814214MAP3K1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligaseENSG00000095015600982, 613762
4296-0.39078.613-1.8680.062740.9609-4.164296MAP3K11mitogen-activated protein kinase kinase kinase 11ENSG00000173327600050
43-0.29064.257-2.0040.045980.9609-4.05743ACHEacetylcholinesteraseENSG00000087085100740, 112100
43130.33444.7181.6630.097330.9609-4.3014313MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)ENSG00000087245120360, 259600
4650-0.49666.463-1.8080.071640.9609-4.2034650MYO9Bmyosin IXBENSG00000099331602129, 609753
47630.41844.7832.630.0089760.9609-3.4964763NF1neurofibromin 1ENSG00000196712162200, 162210, 193520, 601321, 607785, 613113
4843-0.18684.164-1.9580.05120.9609-4.0934843NOS2nitric oxide synthase 2, inducibleENSG00000007171145500, 163730, 248310, 611162
5062-0.35667.174-1.570.11760.9609-4.3615062PAK2p21 protein (Cdc42/Rac)-activated kinase 2ENSG00000180370605022
515610.8355.6141.8150.07050.9609-4.19851561IL23Ainterleukin 23, alpha subunit p19ENSG00000110944605580
53280.911710.872.1120.035510.9609-3.975328PLAUplasminogen activator, urokinaseENSG00000122861104300, 191840, 601709
55114-0.41538.628-2.2260.026740.9609-3.87455114ARHGAP17Rho GTPase activating protein 17ENSG00000140750608293
5594-0.18929.713-1.740.082830.9609-4.255594MAPK1mitogen-activated protein kinase 1ENSG00000100030176948
56000.3124.9031.4620.14470.9609-4.4255600MAPK11mitogen-activated protein kinase 11ENSG00000185386602898
5606-0.48449.058-1.7030.089650.9609-4.2755606MAP2K3mitogen-activated protein kinase kinase 3ENSG00000034152602315
56080.42417.9551.6110.10810.9609-4.3355608MAP2K6mitogen-activated protein kinase kinase 6ENSG00000108984601254
5609-0.42574.643-1.9450.052780.9609-4.1035609MAP2K7mitogen-activated protein kinase kinase 7ENSG00000076984603014
5728-0.43224.498-1.9020.058140.9609-4.1355728PTENphosphatase and tensin homologENSG00000171862137800, 153480, 155600, 158350, 174900, 176807, 176920, 188470, 275355, 276950, 601728, 605309, 607174, 608089, 612242, 613028
575720.16313.8471.4740.14160.9609-4.41857572DOCK6dedicator of cytokinesis 6ENSG00000130158614194, 614219
57591-0.22554.8-1.910.057110.9609-4.12957591MKL1megakaryoblastic leukemia (translocation) 1ENSG00000196588606078
5879-0.256912.69-2.2030.028330.9609-3.8945879RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)ENSG00000136238602048
5910-0.27559.86-2.0390.042290.9609-4.0295910RAP1GDS1RAP1, GTP-GDP dissociation stimulator 1ENSG00000138698179502
596-0.25694.863-1.4040.16150.9609-4.458596BCL2B-cell CLL/lymphoma 2ENSG00000171791151430
64160.57878.0912.0590.040410.9609-4.0146416MAP2K4mitogen-activated protein kinase kinase 4ENSG00000065559601335
66540.32376.1631.3880.16620.9609-4.4666654SOS1son of sevenless homolog 1 (Drosophila)ENSG00000115904135300, 163955, 182530, 610733
672-0.45697.28-2.1620.031430.9609-3.929672BRCA1breast cancer 1, early onsetENSG00000012048113705, 114480, 604370, 614320
6722-0.36698.306-1.9570.05130.9609-4.0936722SRFserum response factor (c-fos serum response element-binding transcription factor)ENSG00000112658600589
7074-0.46338.01-1.8740.061980.9609-4.1567074TIAM1T-cell lymphoma invasion and metastasis 1ENSG00000156299600687
7204-0.20473.959-1.6050.10970.9609-4.3397204TRIOtriple functional domain (PTPRF interacting)ENSG00000038382601893
7414-0.113412.74-1.4420.15040.9609-4.4367414VCLvinculinENSG00000035403193065, 611407, 613255
7430-0.250310.14-1.7250.085570.9609-4.267430EZRezrinENSG00000092820123900
83940.56844.982.0440.041850.9609-4.0258394PIP5K1Aphosphatidylinositol-4-phosphate 5-kinase, type I, alphaENSG00000143398603275
8452-0.22774.425-1.4040.16130.9609-4.4578452CUL3cullin 3ENSG00000036257603136, 614496
8826-0.235710.07-1.7180.086830.9609-4.2658826IQGAP1IQ motif containing GTPase activating protein 1ENSG00000140575603379
90210.21593.9721.9770.048990.9609-4.0789021SOCS3suppressor of cytokine signaling 3ENSG00000184557604176, 605805
9639-0.50114.498-1.7640.078790.9609-4.2349639ARHGEF10Rho guanine nucleotide exchange factor (GEF) 10ENSG00000104728608136, 608236
9990.53249.3391.4040.16150.9609-4.458999CDH1cadherin 1, type 1, E-cadherin (epithelial)ENSG00000039068114480, 137215, 167000, 176807, 192090, 608089