Test Results

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Gene Set Null EGF receptor (ErbB1) signaling pathway

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10066-0.41118.306-1.8440.066140.9609-4.17710066SCAMP2secretory carrier membrane protein 2ENSG00000140497606912
10075-0.292710.14-1.580.11520.9609-4.35410075HUWE1HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligaseENSG00000086758300220, 300697, 300706
10093-0.33479.258-2.1090.03580.9609-3.97310093ARPC4actin related protein 2/3 complex, subunit 4, 20kDaENSG00000241553604226
100940.260511.361.6380.10250.9609-4.31810094ARPC3actin related protein 2/3 complex, subunit 3, 21kDaENSG00000111229604225
10155-0.522110.41-1.6590.098240.9609-4.30410155TRIM28tripartite motif containing 28ENSG00000130726601742
10163-0.52088.577-2.4380.015340.9609-3.68310163WASF2WAS protein family, member 2ENSG00000158195605875
1029-0.77786.811-2.5290.011940.9609-3.5961029CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)ENSG00000147889151623, 155601, 155755, 600160, 606719
103250.39865.0571.8460.065940.9609-4.17610325RRAGBRas-related GTP binding BENSG00000083750300725
10454-0.19934.997-1.460.14520.9609-4.42610454TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 1ENSG00000100324602615
10458-0.22374.395-1.7780.076490.9609-4.22410458BAIAP2BAI1-associated protein 2ENSG00000175866605475
105240.42917.0721.7620.079120.9609-4.23510524KAT5K(lysine) acetyltransferase 5ENSG00000172977601409
106170.28949.2071.4590.14580.9609-4.42710617STAMBPSTAM binding proteinENSG00000124356606247
109120.18114.4191.7760.076680.9609-4.22510912GADD45Ggrowth arrest and DNA-damage-inducible, gammaENSG00000130222604949
11099-0.21914.313-1.7460.081820.9609-4.24611099PTPN21protein tyrosine phosphatase, non-receptor type 21ENSG00000070778603271
112000.33166.5211.4810.13960.9609-4.41411200CHEK2checkpoint kinase 2ENSG00000183765114480, 176807, 259500, 604373, 609265
1124-0.16674.05-1.640.1020.9609-4.3161124CHN2chimerin (chimaerin) 2ENSG00000106069602857
12110.34645.1442.490.013320.9609-3.6341211CLTAclathrin, light chain AENSG00000122705118960
12770.29994.0572.9220.0037440.9609-3.1861277COL1A1collagen, type I, alpha 1ENSG00000108821114000, 120150, 130000, 130060, 166200, 166210, 166220, 166710, 259420
13900.38578.8132.0890.037560.9609-3.9891390CREMcAMP responsive element modulatorENSG00000095794123812
1398-0.27379.42-2.0110.045270.9609-4.0521398CRKv-crk sarcoma virus CT10 oncogene homolog (avian)ENSG00000167193164762
14320.56886.9351.9680.050020.9609-4.0851432MAPK14mitogen-activated protein kinase 14ENSG00000112062600289
14350.17544.311.5880.11340.9609-4.3491435CSF1colony stimulating factor 1 (macrophage)ENSG00000184371120420
14370.40144.3752.420.016120.9609-3.71437CSF2colony stimulating factor 2 (granulocyte-macrophage)ENSG00000164400138960
1445-0.50158.287-2.1130.035470.9609-3.971445CSKc-src tyrosine kinaseENSG00000103653124095
1452-0.193811.39-1.7920.074220.9609-4.2141452CSNK1A1casein kinase 1, alpha 1ENSG00000113712600505
1453-0.29319.618-2.6390.0087570.9609-3.4871453CSNK1Dcasein kinase 1, deltaENSG00000141551600864
1454-0.37157.495-1.4930.13640.9609-4.4061454CSNK1Ecasein kinase 1, epsilonENSG00000213923600863
14560.23077.8911.4030.16160.9609-4.4581456CSNK1G3casein kinase 1, gamma 3ENSG00000151292604253
14621.4216.1821.8680.062690.9609-4.1591462VCANversicanENSG00000038427118661, 143200
1495-0.3174.364-1.8840.060580.9609-4.1481495CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDaENSG00000044115116805
1540-0.47496.162-1.9890.047660.9609-4.0691540CYLDcylindromatosis (turban tumor syndrome)ENSG00000083799132700, 601606, 605018, 605041
16060.57084.8072.1080.035910.9609-3.9741606DGKAdiacylglycerol kinase, alpha 80kDaENSG00000065357125855
16430.3127.3581.4310.15340.9609-4.4421643DDB2damage-specific DNA binding protein 2, 48kDaENSG00000134574278740, 600811
1729-0.40628.661-2.3680.018520.9609-3.7481729DIAPH1diaphanous homolog 1 (Drosophila)ENSG00000131504124900, 602121
17390.57065.6481.7570.07990.9609-4.2381739DLG1discs, large homolog 1 (Drosophila)ENSG00000075711601014
18270.13773.7731.4360.1520.9609-4.441827RCAN1regulator of calcineurin 1ENSG00000159200602917
1847-0.71118.872-1.6740.095090.9609-4.2941847DUSP5dual specificity phosphatase 5ENSG00000138166603069
1869-0.32046.356-1.4990.13490.9609-4.4031869E2F1E2F transcription factor 1ENSG00000101412189971
1910-0.24423.949-1.6120.1080.9609-4.3341910EDNRBendothelin receptor type BENSG00000136160131244, 277580, 600155, 600501
19420.39457.4751.5010.13430.9609-4.4021942EFNA1ephrin-A1ENSG00000169242191164
19560.67775.6911.8380.067130.9609-4.1821956EGFRepidermal growth factor receptorENSG00000146648131550, 211980
19580.81594.7671.6130.10780.9609-4.3331958EGR1early growth response 1ENSG00000120738128990
2002-0.35899.022-1.8410.066550.9609-4.1792002ELK1ELK1, member of ETS oncogene familyENSG00000126767311040
20170.45646.5181.4520.14750.9609-4.432017CTTNcortactinENSG00000085733164765
2033-0.53327.683-2.1810.029970.9609-3.9132033EP300E1A binding protein p300ENSG00000100393114500, 180849, 602700, 613684
207-0.28259.263-1.6370.10260.9609-4.318207AKT1v-akt murine thymoma viral oncogene homolog 1ENSG00000142208114480, 114500, 164730, 167000, 176920, 181500, 604370
2099-0.29784.373-2.3930.017340.9609-3.7252099ESR1estrogen receptor 1ENSG00000091831133430, 157300, 608446
21151.3025.3913.860.00013930.3879-1.9962115ETV1ets variant 1ENSG00000006468600541
22680.20354.2921.5490.12240.9609-4.3732268FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homologENSG00000000938164940
22943-0.176713.09-1.5430.12390.9609-4.37722943DKK1dickkopf 1 homolog (Xenopus laevis)ENSG00000107984605189
231630.33364.8621.8890.05990.9609-4.14423163GGA3golgi-associated, gamma adaptin ear containing, ARF binding protein 3ENSG00000125447606006
232650.19884.4241.470.14270.9609-4.4223265EXOC7exocyst complex component 7ENSG00000182473608163
23396-0.36877.272-1.5990.11090.9609-4.34323396PIP5K1Cphosphatidylinositol-4-phosphate 5-kinase, type I, gammaENSG00000186111606102, 611369
234330.26069.311.5030.13390.9609-4.40123433RHOQras homolog family member QENSG00000119729605857
23523-0.59056.137-2.7080.0071640.9609-3.41623523CABIN1calcineurin binding protein 1ENSG00000099991604251
23530.39884.8732.1860.029590.9609-3.9092353FOSFBJ murine osteosarcoma viral oncogene homologENSG00000170345164810
23770-0.56076.828-1.9720.049570.9609-4.08223770FKBP8FK506 binding protein 8, 38kDaENSG00000105701604840
25805-0.4687.104-1.9590.051030.9609-4.09225805BAMBIBMP and activin membrane-bound inhibitor homolog (Xenopus laevis)ENSG00000095739604444
26585-0.25444.238-1.440.15090.9609-4.43726585GREM1gremlin 1ENSG00000166923603054
2664-0.4729.372-2.8360.0048840.9609-3.2812664GDI1GDP dissociation inhibitor 1ENSG00000203879300104, 300849, 309541
269590.35628.1411.7760.076690.9609-4.22526959HBP1HMG-box transcription factor 1ENSG00000105856NA
272520.66827.2651.8630.063510.9609-4.16427252KLHL20kelch-like 20 (Drosophila)ENSG00000076321NA
274-0.4478.038-2.5040.012830.9609-3.621274BIN1bridging integrator 1ENSG00000136717255200, 601248
2767-0.57939.842-2.970.003220.9609-3.1322767GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)ENSG00000088256139313
28870.64035.6351.9440.052780.9609-4.1032887GRB10growth factor receptor-bound protein 10ENSG00000106070601523
291080.36786.3211.4370.15170.9609-4.43929108PYCARDPYD and CARD domain containingENSG00000103490606838
29340.3544.8192.5560.011090.9609-3.572934GSNgelsolinENSG00000148180105120, 137350
29895-0.19364.865-1.5610.11960.9609-4.36629895MYLPFmyosin light chain, phosphorylatable, fast skeletal muscleENSG00000180209NA
3082-0.20424.025-1.9210.055710.9609-4.1213082HGFhepatocyte growth factor (hepapoietin A; scatter factor)ENSG00000019991142409, 608265
3159-0.437311.06-1.9110.056980.9609-4.1283159HMGA1high mobility group AT-hook 1ENSG00000137309125853, 600701
31640.27364.9671.8420.066470.9609-4.1783164NR4A1nuclear receptor subfamily 4, group A, member 1ENSG00000123358139139
3265-0.41518.995-2.1540.032080.9609-3.9363265HRASv-Ha-ras Harvey rat sarcoma viral oncogene homologENSG00000174775109800, 188470, 190020, 218040
3303-0.262212.18-1.6310.10410.9609-4.3223303HSPA1Aheat shock 70kDa protein 1AENSG00000234475, ENSG00000231555, ENSG00000235941, ENSG00000232804, ENSG00000204389, ENSG00000204388, ENSG00000237724, ENSG00000224501, ENSG00000215328, ENSG00000212866140550
3310.29185.0171.7230.085930.9609-4.262331XIAPX-linked inhibitor of apoptosisENSG00000101966300079, 300635
3480-0.36525.821-1.4010.16230.9609-4.4593480IGF1Rinsulin-like growth factor 1 receptorENSG00000140443147370, 270450
3550.80395.3962.1540.032010.9609-3.935355FASFas (TNF receptor superfamily, member 6)ENSG00000026103134637, 601859
35510.21534.3551.5940.11210.9609-4.3463551IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase betaENSG00000104365603258
3558-0.52014.72-1.4810.13970.9609-4.4143558IL2interleukin 2ENSG00000109471147680
3565-0.15073.905-1.5320.12660.9609-4.3843565IL4interleukin 4ENSG00000113520147780
35761.2388.2971.520.12960.9609-4.3913576IL8interleukin 8ENSG00000169429146930
3597-0.20698.827-1.3940.16420.9609-4.4633597IL13RA1interleukin 13 receptor, alpha 1ENSG00000131724300119
362-0.18194.394-1.4870.13810.9609-4.41362AQP5aquaporin 5ENSG00000161798600442
3636-0.43587.705-1.7710.077550.9609-4.2293636INPPL1inositol polyphosphate phosphatase-like 1ENSG00000165458600829
3674-0.33894.275-1.5240.12850.9609-4.3883674ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)ENSG00000005961273800, 607759
3688-0.21463.976-1.8220.069450.9609-4.1933688ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)ENSG00000150093135630
36900.16853.8451.9320.054360.9609-4.1123690ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)ENSG00000259753, ENSG00000259207173470, 273800, 608446
37180.12764.1481.4160.15780.9609-4.4513718JAK3Janus kinase 3ENSG00000105639600173
3836-0.452210.28-2.8030.0053980.9609-3.3163836KPNA1karyopherin alpha 1 (importin alpha 5)ENSG00000114030600686
38800.513911.421.5180.13010.9609-4.3923880KRT19keratin 19ENSG00000171345148020
3925-0.7396.414-1.5890.11310.9609-4.3493925STMN1stathmin 1ENSG00000117632151442
4067-0.4516.436-1.5030.13390.9609-4.4014067LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homologENSG00000254087165120
4080.25554.6471.9370.053670.9609-4.108408ARRB1arrestin, beta 1ENSG00000137486107940
40900.57086.7551.680.0940.9609-4.294090SMAD5SMAD family member 5ENSG00000113658603110
4094-0.2734.184-1.4760.1410.9609-4.4174094MAFv-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)ENSG00000178573177075, 610202
4170-0.252410.91-1.9630.050550.9609-4.0884170MCL1myeloid cell leukemia sequence 1 (BCL2-related)ENSG00000143384159552
4193-0.1884.275-1.4810.13960.9609-4.4144193MDM2Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)ENSG00000135679164785, 614401
4214-0.44744.64-1.6930.091440.9609-4.2814214MAP3K1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligaseENSG00000095015600982, 613762
4215-0.31977.869-1.5090.13230.9609-4.3974215MAP3K3mitogen-activated protein kinase kinase kinase 3ENSG00000198909602539
42170.55565.0082.2350.026180.9609-3.8674217MAP3K5mitogen-activated protein kinase kinase kinase 5ENSG00000197442602448
4802-0.74867.396-3.3720.00084630.7834-2.6524802NFYCnuclear transcription factor Y, gammaENSG00000066136605344