Test Results

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Gene Set Null Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10274-1.4467.37-5.7412.326e-089.105e-078.70710274STAG1stromal antigen 1ENSG00000118007604358
10735-0.841810.4-8.2455.395e-159.933e-1323.510735STAG2stromal antigen 2ENSG00000101972300826
11065-0.54211.13-3.4130.00073310.006905-1.09811065UBE2Cubiquitin-conjugating enzyme E2CENSG00000175063605574
231980.513410.323.5850.00039470.004108-0.526523198PSME4proteasome (prosome, macropain) activator subunit 4ENSG00000068878607705
324-0.61526.847-3.1780.0016370.01349-1.834324APCadenomatous polyposis coliENSG00000134982114500, 114550, 135290, 137215, 155255, 175100, 276300, 611731, 613659
51433-0.480811.08-3.9918.311e-050.0010960.924651433ANAPC5anaphase promoting complex subunit 5ENSG00000089053606948
5347-1.9768.164-8.5188.263e-161.878e-1325.335347PLK1polo-like kinase 1ENSG00000166851602098
5688-0.30412.22-2.6440.0086360.05137-3.3325688PSMA7proteasome (prosome, macropain) subunit, alpha type, 7ENSG00000101182606607
56981.5845.1075.732.47e-089.569e-078.6495698PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)ENSG00000242711, ENSG00000240065, ENSG00000243594, ENSG00000240118, ENSG00000243067, ENSG00000239836, ENSG00000240508, ENSG00000243958177045
5701-0.58258.969-3.6350.00032730.003489-0.35325701PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 2ENSG00000161057154365
5704-0.382410.33-2.4830.013570.07323-3.735704PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 4ENSG00000013275602707
5705-0.400712.17-2.5390.011640.06492-3.5955705PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 5ENSG00000087191601681
5711-0.49338.669-3.9060.00011610.0014570.61175711PSMD5proteasome (prosome, macropain) 26S subunit, non-ATPase, 5ENSG00000095261604452
5713-1.0539.303-5.3012.251e-076.606e-066.535713PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 7ENSG00000103035157970
5717-1.0366.128-4.5846.731e-060.00012413.2935717PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 11ENSG00000108671604449
5718-0.462110.49-3.2250.0013980.01178-1.695718PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 12ENSG00000197170604450
57200.319511.012.4830.013570.07323-3.735720PSME1proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)ENSG00000092010600654
5885-0.644911.07-4.0785.839e-050.00080741.2565885RAD21RAD21 homolog (S. pombe)ENSG00000164754606462
65000.399711.343.0470.0025210.01914-2.2276500SKP1S-phase kinase-associated protein 1ENSG00000113558601434
701-0.48359.852-3.5290.00048350.004869-0.7144701BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)ENSG00000156970114500, 176430, 257300, 602860
73140.60917.8522.7320.0066640.04199-3.1017314UBBubiquitin BENSG00000170315119540, 191339
73210.59139.7993.0470.0025220.01914-2.2287321UBE2D1ubiquitin-conjugating enzyme E2D 1ENSG00000072401602961
8243-0.784910.23-5.5067.946e-082.699e-067.5288243SMC1Astructural maintenance of chromosomes 1AENSG00000072501300040, 300590
8312-0.51796.36-2.740.006510.04119-3.0818312AXIN1axin 1ENSG00000103126114550, 603816, 607864
8454-1.4469.338-8.3632.405e-154.7e-1324.298454CUL1cullin 1ENSG00000055130603134
8697-0.73968.711-4.1294.736e-050.00067191.4528697CDC23cell division cycle 23 homolog (S. cerevisiae)ENSG00000094880603462
8881-0.58887.692-48.014e-050.0010620.95878881CDC16cell division cycle 16 homolog (S. cerevisiae)ENSG00000130177603461
891-0.612510.69-5.6174.476e-081.608e-068.079891CCNB1cyclin B1ENSG00000134057123836
9184-1.1410.2-10.021.499e-208.787e-1835.979184BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)ENSG00000154473603719
98610.388210.792.4680.014170.07566-3.7689861PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 6ENSG00000163636NA
996-0.45079.517-4.4221.374e-050.00023282.618996CDC27cell division cycle 27 homolog (S. cerevisiae)ENSG00000004897116946