Test Results

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Gene Set Null Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10274-1.6027.37-13.741.438e-331.54e-3165.5210274STAG1stromal antigen 1ENSG00000118007604358
10393-0.86788.154-8.0122.598e-144.675e-1321.6410393ANAPC10anaphase promoting complex subunit 10ENSG00000164162613745
10735-0.703510.4-14.897.985e-381.271e-3575.2410735STAG2stromal antigen 2ENSG00000101972300826
11065-0.629211.13-8.5596.239e-161.324e-1425.3111065UBE2Cubiquitin-conjugating enzyme E2CENSG00000175063605574
1452-0.178211.48-4.1214.898e-050.00027790.85431452CSNK1A1casein kinase 1, alpha 1ENSG00000113712600505
26271-1.158.424-8.3253.126e-156.239e-1423.7226271FBXO5F-box protein 5ENSG00000112029606013
324-0.4526.847-5.0467.868e-075.9e-064.81324APCadenomatous polyposis coliENSG00000134982114500, 114550, 135290, 137215, 155255, 175100, 276300, 611731, 613659
5347-1.4898.164-13.864.891e-345.53e-3266.595347PLK1polo-like kinase 1ENSG00000166851602098
5682-0.244711.63-3.9180.0001110.00059430.080065682PSMA1proteasome (prosome, macropain) subunit, alpha type, 1ENSG00000256206, ENSG00000129084602854
56981.1575.1079.0422.046e-174.938e-1628.685698PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)ENSG00000242711, ENSG00000240065, ENSG00000243594, ENSG00000240118, ENSG00000243067, ENSG00000239836, ENSG00000240508, ENSG00000243958177045
5700-0.220911.62-4.0157.547e-050.00041490.44455700PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 1ENSG00000100764602706
5701-0.32611.9-7.6243.337e-135.368e-1219.135701PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 2ENSG00000161057154365
5711-0.31588.669-5.4041.34e-071.127e-066.5215711PSMD5proteasome (prosome, macropain) 26S subunit, non-ATPase, 5ENSG00000095261604452
5713-0.89189.303-9.6971.708e-194.961e-1833.415713PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 7ENSG00000103035157970
5717-0.84076.128-8.0372.192e-143.984e-1321.85717PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 11ENSG00000108671604449
5718-0.266311.3-5.8941.022e-089.96e-089.0195718PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 12ENSG00000197170604450
5885-0.469911.07-6.425.38e-106.152e-0911.895885RAD21RAD21 homolog (S. pombe)ENSG00000164754606462
65000.42688.658.3842.083e-154.23e-1424.126500SKP1S-phase kinase-associated protein 1ENSG00000113558601434
701-0.44499.852-7.0171.546e-112.098e-1015.36701BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)ENSG00000156970114500, 176430, 257300, 602860
73210.38169.7994.2482.889e-050.00017071.3567321UBE2D1ubiquitin-conjugating enzyme E2D 1ENSG00000072401602961
8243-0.510.23-7.5794.477e-137.094e-1218.848243SMC1Astructural maintenance of chromosomes 1AENSG00000072501300040, 300590
8454-1.3739.338-17.172.388e-467.601e-4494.728454CUL1cullin 1ENSG00000055130603134
8697-0.72148.711-8.7022.299e-165.07e-1526.298697CDC23cell division cycle 23 homolog (S. cerevisiae)ENSG00000094880603462
8881-0.54447.692-7.993.009e-145.367e-1321.498881CDC16cell division cycle 16 homolog (S. cerevisiae)ENSG00000130177603461
891-0.757310.69-15.012.892e-384.808e-3676.25891CCNB1cyclin B1ENSG00000134057123836
9126-0.54499.068-5.1385.034e-073.902e-065.2419126SMC3structural maintenance of chromosomes 3ENSG00000108055606062, 610759
9184-1.09310.2-20.769.6e-607.921e-57125.39184BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)ENSG00000154473603719
92320.177411.954.0037.912e-050.00043310.39979232PTTG1pituitary tumor-transforming 1ENSG00000164611604147
996-0.83019.37-9.8595.104e-201.551e-1834.6996CDC27cell division cycle 27 homolog (S. cerevisiae)ENSG00000004897116946