Test Results

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Gene Set Null Class I PI3K signaling events

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
100180.50154.4344.1694.026e-050.00058211.60510018BCL2L11BCL2-like 11 (apoptosis facilitator)ENSG00000153094603827
10163-1.068.577-4.9661.158e-062.679e-054.96610163WASF2WAS protein family, member 2ENSG00000158195605875
10262.0288.0045.479.581e-083.167e-067.3491026CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)ENSG00000124762116899
10510.879610.33.8610.00013840.0016880.44761051CEBPBCCAAT/enhancer binding protein (C/EBP), betaENSG00000172216189965
10524-1.1037.19-6.0065.536e-092.58e-0710.0910524KAT5K(lysine) acetyltransferase 5ENSG00000172977601409
105801.0024.6345.2562.815e-077.917e-066.31710580SORBS1sorbin and SH3 domain containing 1ENSG00000095637605264
10787-0.479810.5-3.7370.00022350.0025080.00124410787NCKAP1NCK-associated protein 1ENSG00000061676604891
112611.3686.314.0147.556e-050.0010131.01411261CHPcalcium binding protein P22ENSG00000187446606988
1387-1.8688.584-7.6353.119e-133.947e-1119.561387CREBBPCREB binding proteinENSG00000005339180849, 600140
1434-0.492211.41-4.0975.402e-050.00075461.3281434CSE1LCSE1 chromosome segregation 1-like (yeast)ENSG00000124207601342
1445-0.96858.287-4.085.8e-050.00080251.2621445CSKc-src tyrosine kinaseENSG00000103653124095
1453-1.1749.618-10.572.276e-221.95e-1940.061453CSNK1Dcasein kinase 1, deltaENSG00000141551600864
1457-0.8219.992-6.8813.539e-112.815e-0914.971457CSNK2A1casein kinase 2, alpha 1 polypeptideENSG00000101266115440
1541.898.7596.854.261e-113.343e-0914.79154ADRB2adrenergic, beta-2-, receptor, surfaceENSG00000169252109690, 600807, 601665
16471.06910.154.3591.804e-050.00029462.3611647GADD45Agrowth arrest and DNA-damage-inducible, alphaENSG00000116717126335
18431.4265.1166.5642.337e-101.536e-0813.141843DUSP1dual specificity phosphatase 1ENSG00000120129600714
18471.6058.8723.7790.000190.0021860.15241847DUSP5dual specificity phosphatase 5ENSG00000138166603069
1851.124.534.9631.174e-062.703e-054.953185AGTR1angiotensin II receptor, type 1ENSG00000144891106165, 145500, 267430
1871-1.358.431-5.5645.901e-082.044e-067.8131871E2F3E2F transcription factor 3ENSG00000112242600427
19591.3244.815.1594.541e-071.194e-055.8591959EGR2early growth response 2ENSG00000122877129010, 145900, 605253, 607678
1975-0.890110.61-5.1953.809e-071.021e-056.0271975EIF4Beukaryotic translation initiation factor 4BENSG00000063046603928
2033-1.5216.866-6.4644.172e-102.532e-0812.582033EP300E1A binding protein p300ENSG00000100393114500, 180849, 602700, 613684
22943-0.725213.09-6.3338.879e-105.02e-0811.8522943DKK1dickkopf 1 homolog (Xenopus laevis)ENSG00000107984605189
23081.1326.484.7253.564e-067.145e-053.8972308FOXO1forkhead box O1ENSG00000150907136533, 268220
230850.82246.3013.5920.00038450.004019-0.502323085ERC1ELKS/RAB6-interacting/CAST family member 1ENSG00000082805607127
233031.226.5995.3871.457e-074.584e-066.94723303KIF13Bkinesin family member 13BENSG00000197892607350
23531.2174.8736.6711.241e-108.83e-0913.752353FOSFBJ murine osteosarcoma viral oncogene homologENSG00000170345164810
25-0.72758.128-4.451.218e-050.00020952.73225ABL1c-abl oncogene 1, non-receptor tyrosine kinaseENSG00000097007189980
25341.5098.7256.8434.456e-113.483e-0914.752534FYNFYN oncogene related to SRC, FGR, YESENSG00000010810137025
25898-1.0348.447-4.5467.955e-060.00014383.13525898RCHY1ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligaseENSG00000163743607680
272440.7786.2073.9659.189e-050.0011930.830627244SESN1sestrin 1ENSG00000080546606103
28870.66078.8954.2942.376e-050.00037462.1012887GRB10growth factor receptor-bound protein 10ENSG00000106070601523
289841.3195.1366.1182.985e-091.505e-0710.6828984RGCCregulator of cell cycleENSG00000102760610077
3169-2.3146.701-6.3617.578e-104.362e-0812.013169FOXA1forkhead box A1ENSG00000129514602294
3170.73515.3313.790.00018280.0021170.1884317APAF1apoptotic peptidase activating factor 1ENSG00000120868602233
33030.791712.184.9231.414e-063.164e-054.7763303HSPA1Aheat shock 70kDa protein 1AENSG00000234475, ENSG00000231555, ENSG00000235941, ENSG00000232804, ENSG00000204389, ENSG00000204388, ENSG00000237724, ENSG00000224501, ENSG00000215328, ENSG00000212866140550
3603.8615.58911.37.144e-251.137e-2145.69360AQP3aquaporin 3 (Gill blood group)ENSG00000165272600170, 607457
3636-1.1077.705-4.4979.877e-060.00017382.933636INPPL1inositol polyphosphate phosphatase-like 1ENSG00000165458600829
37261.1968.4745.3162.087e-076.2e-066.6033726JUNBjun B proto-oncogeneENSG00000171223165161
37910.63244.2564.8232.267e-064.838e-054.3263791KDRkinase insert domain receptor (a type III receptor tyrosine kinase)ENSG00000128052191306, 602089
3836-0.68579.274-5.461.007e-073.31e-067.3013836KPNA1karyopherin alpha 1 (importin alpha 5)ENSG00000114030600686
3837-0.860311.65-7.536.134e-137.549e-1118.93837KPNB1karyopherin (importin) beta 1ENSG00000108424602738
3976-2.4487.137-7.2224.317e-124.218e-1017.013976LIFleukemia inhibitory factorENSG00000128342159540
41700.78069.4915.6613.555e-081.322e-068.34170MCL1myeloid cell leukemia sequence 1 (BCL2-related)ENSG00000143384159552
4193-0.44334.983-3.8390.00015130.0018190.36484193MDM2Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)ENSG00000135679164785, 614401
46031.4989.2615.8691.173e-085.026e-079.3654603MYBL1v-myb myeloblastosis viral oncogene homolog (avian)-like 1ENSG00000185697159405
4790-0.98857.776-5.5725.661e-081.977e-067.8534790NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1ENSG00000109320164011
4802-1.4927.396-6.729.316e-116.849e-0914.034802NFYCnuclear transcription factor Y, gammaENSG00000066136605344
514741.5499.0634.7583.055e-066.238e-054.04351474LIMA1LIM domain and actin binding 1ENSG00000050405608364
51701.2718.9793.9579.517e-050.0012270.79785170PDPK13-phosphoinositide dependent protein kinase-1ENSG00000140992605213
5329-1.0849.122-5.9278.568e-093.765e-079.6685329PLAURplasminogen activator, urokinase receptorENSG00000011422173391
5347-1.9768.164-8.5188.263e-161.878e-1325.335347PLK1polo-like kinase 1ENSG00000166851602098
53661.5759.8176.0145.321e-092.49e-0710.135366PMAIP1phorbol-12-myristate-13-acetate-induced protein 1ENSG00000141682604959
545411.8057.5565.9497.57e-093.421e-079.78754541DDIT4DNA-damage-inducible transcript 4ENSG00000168209607729
54700-0.7978.615-4.2273.155e-050.00047081.83454700RRN3RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)ENSG00000085721605121
5524-0.98427.441-3.8990.00011950.0014920.58515524PPP2R4protein phosphatase 2A activator, regulatory subunit 4ENSG00000119383600756
55300.69349.3344.881.732e-063.804e-054.5835530PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozymeENSG00000138814114105
55781.0217.3135.1564.627e-071.212e-055.8425578PRKCAprotein kinase C, alphaENSG00000154229176960
55801.8577.4787.4977.596e-139.098e-1118.695580PRKCDprotein kinase C, deltaENSG00000163932176977
55831.1336.6623.7050.00025170.002785-0.10925583PRKCHprotein kinase C, etaENSG00000027075601367, 605437
5610-0.58458.989-3.8240.000160.0018990.31275610EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 2ENSG00000055332176871
57701.3438.3085.0597.381e-071.827e-055.3965770PTPN1protein tyrosine phosphatase, non-receptor type 1ENSG00000196396125853, 176885
5771-0.953710.27-4.9631.171e-062.699e-054.9565771PTPN2protein tyrosine phosphatase, non-receptor type 2ENSG00000175354176887
5829-0.846410.28-3.9410.00010120.0012930.74065829PXNpaxillinENSG00000089159602505
5894-1.0079.525-5.0487.783e-071.907e-055.3455894RAF1v-raf-1 murine leukemia viral oncogene homolog 1ENSG00000132155164760, 611553, 611554
59080.416111.254.3172.16e-050.00034492.1915908RAP1BRAP1B, member of RAS oncogene familyENSG00000127314179530
5970-0.71669.353-4.3092.234e-050.00035582.1595970RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)ENSG00000173039164014
598-1.6549.808-7.6283.256e-134.098e-1119.52598BCL2L1BCL2-like 1ENSG00000171552600039
6041.2925.0545.3871.459e-074.584e-066.946604BCL6B-cell CLL/lymphoma 6ENSG00000113916109565
6249-1.5558.836-8.8249.701e-172.604e-1427.416249CLIP1CAP-GLY domain containing linker protein 1ENSG00000130779179838
641210.47879.733.9569.556e-050.001230.79464121RRAGCRas-related GTP binding CENSG00000116954608267
64411-0.89146.405-4.2552.805e-050.00042651.94564411ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3ENSG00000120318606647
6502-0.668410.17-3.9549.599e-050.0012340.78976502SKP2S-phase kinase-associated protein 2, E3 ubiquitin protein ligaseENSG00000145604601436
6597-0.85339.959-5.6962.945e-081.116e-068.486597SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4ENSG00000127616603254, 613325
66480.89238.1646.9172.84e-112.318e-0915.186648SOD2superoxide dismutase 2, mitochondrialENSG00000112096147460, 612634
67201.767.3134.7842.718e-065.658e-054.1546720SREBF1sterol regulatory element binding transcription factor 1ENSG00000072310184756
67720.670910.585.0477.83e-071.915e-055.3396772STAT1signal transducer and activator of transcription 1, 91kDaENSG00000115415209950, 600555, 613796, 614162
7027-0.571710.46-4.3032.287e-050.00036272.1377027TFDP1transcription factor Dp-1ENSG00000198176189902
71590.83928.5865.1774.156e-071.102e-055.9447159TP53BP2tumor protein p53 binding protein, 2ENSG00000143514602143
7323-0.293210.44-3.8140.00016660.0019570.2757323UBE2D3ubiquitin-conjugating enzyme E2D 3ENSG00000109332602963
74140.41812.745.3162.087e-076.2e-066.6037414VCLvinculinENSG00000035403193065, 611407, 613255
7514-0.934411.74-10.661.088e-221.101e-1940.787514XPO1exportin 1 (CRM1 homolog, yeast)ENSG00000082898602559
7528-0.501411.26-4.4181.398e-050.00023612.6027528YY1YY1 transcription factorENSG00000100811600013
77630.95329.3245.7182.631e-081.012e-068.5897763ZFAND5zinc finger, AN1-type domain 5ENSG00000107372604761
7874-0.81619.385-4.4041.485e-050.00024872.5457874USP7ubiquitin specific peptidase 7 (herpes virus-associated)ENSG00000187555602519
8061-1.87711.23-7.8816.229e-149.069e-1221.128061FOSL1FOS-like antigen 1ENSG00000175592136515
8295-0.74428.766-4.3042.28e-050.00036172.148295TRRAPtransformation/transcription domain-associated proteinENSG00000196367603015
8420.97218.2536.0933.43e-091.69e-0710.55842CASP9caspase 9, apoptosis-related cysteine peptidaseENSG00000132906602234
84271-1.3138.157-6.5872.038e-101.363e-0813.2784271POLDIP3polymerase (DNA-directed), delta interacting protein 3ENSG00000100227611520
86601.6897.0855.7682.011e-088.043e-078.8478660IRS2insulin receptor substrate 2ENSG00000185950125853, 600797
8680.93818.495.3212.039e-076.104e-066.625868CBLBCbl proto-oncogene, E3 ubiquitin protein ligase BENSG00000114423604491
87-0.523112.17-3.6280.0003360.003565-0.377387ACTN1actinin, alpha 1ENSG00000072110102575
87951.7556.0695.1993.735e-071.004e-056.0468795TNFRSF10Btumor necrosis factor receptor superfamily, member 10bENSG00000120889275355, 603612
890-0.82978.752-4.1833.795e-050.0005531.66890CCNA2cyclin A2ENSG00000145386123835
891-0.612510.69-5.6174.476e-081.608e-068.079891CCNB1cyclin B1ENSG00000134057123836
9000.564310.715.3611.669e-075.163e-066.817900CCNG1cyclin G1ENSG00000113328601578
90430.866110.395.3391.857e-075.659e-066.7149043SPAG9sperm associated antigen 9ENSG00000008294605430
9266-0.94067.305-5.2253.282e-078.927e-066.179266CYTH2cytohesin 2ENSG00000105443602488
94670.91389.3724.3871.596e-050.00026362.4769467SH3BP5SH3-domain binding protein 5 (BTK-associated)ENSG00000131370605612
98210.7368.2013.7670.00019940.002280.10729821RB1CC1RB1-inducible coiled-coil 1ENSG00000023287114480, 606837