Test Results

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Gene Set Null TNF receptor signaling pathway

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
103990.65746.8323.1830.0016140.01332-1.82210399GNB2L1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1ENSG00000204628176981
10454-0.5854.997-4.2872.456e-050.00038422.0710454TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 1ENSG00000100324602615
10510.879610.33.8610.00013840.0016880.44761051CEBPBCCAAT/enhancer binding protein (C/EBP), betaENSG00000172216189965
112211.4365.4656.0255.01e-092.375e-0710.1811221DUSP10dual specificity phosphatase 10ENSG00000143507608867
112611.3686.314.0147.556e-050.0010131.01411261CHPcalcium binding protein P22ENSG00000187446606988
13260.35934.2512.670.0079930.04844-3.2631326MAP3K8mitogen-activated protein kinase kinase kinase 8ENSG00000107968191195, 211980
1387-1.8688.584-7.6353.119e-133.947e-1119.561387CREBBPCREB binding proteinENSG00000005339180849, 600140
142-0.33410.91-2.8210.0051110.03395-2.864142PARP1poly (ADP-ribose) polymerase 1ENSG00000143799173870
14321.0556.4842.940.0035380.02521-2.5341432MAPK14mitogen-activated protein kinase 14ENSG00000112062600289
1457-0.8219.992-6.8813.539e-112.815e-0914.971457CSNK2A1casein kinase 2, alpha 1 polypeptideENSG00000101266115440
15400.90087.6143.0870.0022140.01723-2.1091540CYLDcylindromatosis (turban tumor syndrome)ENSG00000083799132700, 601606, 605018, 605041
16471.06910.154.3591.804e-050.00029462.3611647GADD45Agrowth arrest and DNA-damage-inducible, alphaENSG00000116717126335
16490.71487.8293.8720.00013280.0016350.48661649DDIT3DNA-damage-inducible transcript 3ENSG00000175197126337, 613488
18431.4265.1166.5642.337e-101.536e-0813.141843DUSP1dual specificity phosphatase 1ENSG00000120129600714
19591.3244.815.1594.541e-071.194e-055.8591959EGR2early growth response 2ENSG00000122877129010, 145900, 605253, 607678
1977-0.7279.441-3.050.0024940.01898-2.2171977EIF4Eeukaryotic translation initiation factor 4EENSG00000151247133440
2005-0.63285.087-3.4010.00076360.00715-1.1362005ELK4ELK4, ETS-domain protein (SRF accessory protein 1)ENSG00000158711600246
2033-1.5216.866-6.4644.172e-102.532e-0812.582033EP300E1A binding protein p300ENSG00000100393114500, 180849, 602700, 613684
229260.39668.142.6830.0077090.04711-3.23122926ATF6activating transcription factor 6ENSG00000118217605537
230431.515.0525.2882.399e-076.941e-066.46923043TNIKTRAF2 and NCK interacting kinaseENSG00000154310610005
230850.82246.3013.5920.00038450.004019-0.502323085ERC1ELKS/RAB6-interacting/CAST family member 1ENSG00000082805607127
23118-0.60828.522-2.9690.0032350.0234-2.45323118TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 2ENSG00000055208605101, 612863
23531.2174.8736.6711.241e-108.83e-0913.752353FOSFBJ murine osteosarcoma viral oncogene homologENSG00000170345164810
25341.5098.7256.8434.456e-113.483e-0914.752534FYNFYN oncogene related to SRC, FGR, YESENSG00000010810137025
269590.50248.1412.5050.012770.06991-3.67726959HBP1HMG-box transcription factor 1ENSG00000105856NA
29340.57974.8194.1853.755e-050.00054751.672934GSNgelsolinENSG00000148180105120, 137350
3170.73515.3313.790.00018280.0021170.1884317APAF1apoptotic peptidase activating factor 1ENSG00000120868602233
3301.7116.4922.4640.01430.07618-3.776330BIRC3baculoviral IAP repeat containing 3ENSG00000023445601721
37261.1968.4745.3162.087e-076.2e-066.6033726JUNBjun B proto-oncogeneENSG00000171223165161
3837-0.860311.65-7.536.134e-137.549e-1118.93837KPNB1karyopherin (importin) beta 1ENSG00000108424602738
38801.24111.423.6640.00029430.00318-0.25463880KRT19keratin 19ENSG00000171345148020
4001-2.477.503-5.2373.095e-078.511e-066.2264001LMNB1lamin B1ENSG00000113368150340, 169500
40670.896.7442.9120.0038670.02718-2.6144067LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homologENSG00000254087165120
41370.6945.3013.4230.00070630.006692-1.0644137MAPTmicrotubule-associated protein tauENSG00000257437, ENSG00000186868157140, 168600, 172700, 260540, 600274, 601104
42081.0697.6084.2782.544e-050.00039512.0374208MEF2Cmyocyte enhancer factor 2CENSG00000081189600662, 613443
42150.5727.8692.70.0073220.04529-3.1854215MAP3K3mitogen-activated protein kinase kinase kinase 3ENSG00000198909602539
4216-0.80278.806-2.9680.0032460.02345-2.4564216MAP3K4mitogen-activated protein kinase kinase kinase 4ENSG00000085511602425
4270.5029.4182.4990.012990.07086-3.692427ASAH1N-acylsphingosine amidohydrolase (acid ceramidase) 1ENSG00000104763228000, 613468
42861.0677.0895.6962.95e-081.116e-068.4794286MITFmicrophthalmia-associated transcription factorENSG00000187098103470, 103500, 156845, 193510
46161.8647.094.7083.841e-067.613e-053.8264616GADD45Bgrowth arrest and DNA-damage-inducible, betaENSG00000099860604948
466-1.2198.875-4.2912.411e-050.00037882.087466ATF1activating transcription factor 1ENSG00000123268123803
47750.56766.9222.6670.008080.04886-3.2734775NFATC3nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3ENSG00000072736602698
4790-0.98857.776-5.5725.661e-081.977e-067.8534790NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1ENSG00000109320164011
4792-0.890910.15-3.2980.0010920.009574-1.4644792NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alphaENSG00000100906164008, 612132
513471.6258.0726.9382.498e-112.068e-0915.3151347TAOK3TAO kinase 3ENSG00000135090NA
5154-1.3096.825-3.3350.00095980.008625-1.3465154PDGFAplatelet-derived growth factor alpha polypeptideENSG00000197461173430
51776-0.47075.384-3.0330.0026390.01984-2.26951776ZAKsterile alpha motif and leucine zipper containing kinase AZKENSG00000091436609479
52920.7675.9593.3210.0010080.008971-1.3915292PIM1pim-1 oncogeneENSG00000137193164960
53211.1835.7783.2650.0012250.01053-1.5695321PLA2G4Aphospholipase A2, group IVA (cytosolic, calcium-dependent)ENSG00000116711600522
55781.0217.3135.1564.627e-071.212e-055.8425578PRKCAprotein kinase C, alphaENSG00000154229176960
55801.8577.4787.4977.596e-139.098e-1118.695580PRKCDprotein kinase C, deltaENSG00000163932176977
55831.1336.6623.7050.00025170.002785-0.10925583PRKCHprotein kinase C, etaENSG00000027075601367, 605437
56061.6688.2215.7652.042e-088.14e-078.8325606MAP2K3mitogen-activated protein kinase kinase 3ENSG00000034152602315
56080.88767.9553.3730.00084310.007763-1.2275608MAP2K6mitogen-activated protein kinase kinase 6ENSG00000108984601254
5610-0.58458.989-3.8240.000160.0018990.31275610EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 2ENSG00000055332176871
56848-0.56416.517-2.6830.00770.0471-3.2356848SPHK2sphingosine kinase 2ENSG00000063176607092
57701.3438.3085.0597.381e-071.827e-055.3965770PTPN1protein tyrosine phosphatase, non-receptor type 1ENSG00000196396125853, 176885
5894-1.0079.525-5.0487.783e-071.907e-055.3455894RAF1v-raf-1 murine leukemia viral oncogene homolog 1ENSG00000132155164760, 611553, 611554
58980.69149.2132.7580.0061790.03961-3.0345898RALAv-ral simian leukemia viral oncogene homolog A (ras related)ENSG00000006451179550
58990.3879.3732.5550.011120.06249-3.5555899RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)ENSG00000144118179551
595-0.95710.4-3.5380.0004680.004732-0.6842595CCND1cyclin D1ENSG00000110092114500, 151400, 168461, 193300, 254500
5970-0.71669.353-4.3092.234e-050.00035582.1595970RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)ENSG00000173039164014
598-1.6549.808-7.6283.256e-134.098e-1119.52598BCL2L1BCL2-like 1ENSG00000171552600039
64160.79718.0912.8350.004890.03279-2.8256416MAP2K4mitogen-activated protein kinase kinase 4ENSG00000065559601335
65481.3448.5195.7472.257e-088.9e-078.7366548SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), member 1ENSG00000090020107310
67091.2375.2175.3821.502e-074.705e-066.9186709SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)ENSG00000197694182810, 613477
6714-1.0127.216-3.2320.0013690.01159-1.6716714SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)ENSG00000197122190090
67201.767.3134.7842.718e-065.658e-054.1546720SREBF1sterol regulatory element binding transcription factor 1ENSG00000072310184756
67720.670910.585.0477.83e-071.915e-055.3396772STAT1signal transducer and activator of transcription 1, 91kDaENSG00000115415209950, 600555, 613796, 614162
68850.44686.8812.5640.010830.06124-3.5316885MAP3K7mitogen-activated protein kinase kinase kinase 7ENSG00000135341602614
6929-0.76376.553-4.0247.277e-050.00098071.0496929TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)ENSG00000071564147141
70910.3214.6462.830.0049660.03319-2.8387091TLE4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)ENSG00000106829605132
7323-0.293210.44-3.8140.00016660.0019570.2757323UBE2D3ubiquitin-conjugating enzyme E2D 3ENSG00000109332602963
7514-0.934411.74-10.661.088e-221.101e-1940.787514XPO1exportin 1 (CRM1 homolog, yeast)ENSG00000082898602559
7531-0.728610.74-2.770.0059510.03837-37531YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptideENSG00000108953247200, 605066
7533-0.77988.591-2.9770.0031520.02288-2.4297533YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptideENSG00000128245113508
7867-0.333510.28-2.5260.012060.06667-3.6267867MAPKAPK3mitogen-activated protein kinase-activated protein kinase 3ENSG00000114738602130
8021-0.72487.102-3.5670.00042010.004334-0.58438021NUP214nucleoporin 214kDaENSG00000126883114350, 601626
8050.248913.062.780.005780.03748-2.974805CALM2calmodulin 2 (phosphorylase kinase, delta)ENSG00000143933, ENSG00000160014, ENSG00000198668114182
8061-1.87711.23-7.8816.229e-149.069e-1221.128061FOSL1FOS-like antigen 1ENSG00000175592136515
837-0.39074.575-2.5840.010240.05859-3.482837CASP4caspase 4, apoptosis-related cysteine peptidaseENSG00000196954602664
839-0.73087.782-3.0530.0024740.01885-2.21839CASP6caspase 6, apoptosis-related cysteine peptidaseENSG00000138794601532
840-0.73947.448-4.0127.626e-050.001021.005840CASP7caspase 7, apoptosis-related cysteine peptidaseENSG00000165806601761
8420.97218.2536.0933.43e-091.69e-0710.55842CASP9caspase 9, apoptosis-related cysteine peptidaseENSG00000132906602234
8439-0.84618.165-3.390.00079240.007383-1.178439NSMAFneutral sphingomyelinase (N-SMase) activation associated factorENSG00000035681603043
84823-0.85978.315-2.4680.014130.07556-3.76584823LMNB2lamin B2ENSG00000176619150341, 608709
85670.69797.1943.2820.0011540.01002-1.5158567MADDMAP-kinase activating death domainENSG00000110514603584
85690.6638.5394.4781.078e-050.00018842.8478569MKNK1MAP kinase interacting serine/threonine kinase 1ENSG00000079277606724
85750.4019.5242.530.011930.06606-3.6178575PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activatorENSG00000180228603424, 612067
8680.93818.495.3212.039e-076.104e-066.625868CBLBCbl proto-oncogene, E3 ubiquitin protein ligase BENSG00000114423604491
8738-0.45086.571-3.2560.001260.0108-1.5958738CRADDCASP2 and RIPK1 domain containing adaptor with death domainENSG00000169372603454
87670.287310.412.4550.014670.07771-3.7988767RIPK2receptor-interacting serine-threonine kinase 2ENSG00000104312603455
8772-1.11810.21-5.7122.71e-081.037e-068.568772FADDFas (TNFRSF6)-associated via death domainENSG00000168040602457, 613759
88781.0555.8245.3511.748e-075.372e-066.7728878SQSTM1sequestosome 1ENSG00000161011601530, 602080
9064-0.72825.886-3.810.00016920.001980.26059064MAP3K6mitogen-activated protein kinase kinase kinase 6ENSG00000142733604468
9448-0.62310.18-3.5740.00041070.004256-0.56359448MAP4K4mitogen-activated protein kinase kinase kinase kinase 4ENSG00000071054604666