Test Results

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Gene Set Broad HELLER_HDAC_TARGETS_UP

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10261.6668.00412.533.319e-297.521e-2855.371026CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)ENSG00000124762116899
10280.83387.1869.1489.559e-181.03e-1629.191028CDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2)ENSG00000129757130650, 600856
103000.96766.0199.7581.085e-191.342e-1833.6210300KATNB1katanin p80 (WD repeat containing) subunit B 1ENSG00000140854602703
10321.5445.84313.971.93e-345.891e-3367.361032CDKN2Dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)ENSG00000129355600927
10499-1.6358.615-18.591.134e-511.098e-49106.910499NCOA2nuclear receptor coactivator 2ENSG00000140396601993
105800.96034.63414.051.006e-343.162e-3368.0110580SORBS1sorbin and SH3 domain containing 1ENSG00000095637605264
107692.1718.38624.512.665e-731.237e-70156.510769PLK2polo-like kinase 2ENSG00000145632607023
108580.47494.3788.7072.208e-162.137e-1526.0910858CYP46A1cytochrome P450, family 46, subfamily A, polypeptide 1ENSG00000036530604087
111470.64675.9068.5984.736e-164.445e-1525.3311147HHLA3HERV-H LTR-associating 3ENSG00000197568604372
1143271.0477.3214.031.148e-343.577e-3367.88114327EFHC1EF-hand domain (C-terminal) containing 1ENSG00000096093254770, 607631, 608815
13620.89897.4112.071.471e-272.981e-2651.61362CPDcarboxypeptidase DENSG00000108582603102
14660.74178.94811.81.275e-262.449e-2549.461466CSRP2cysteine and glycine-rich protein 2ENSG00000175183601871
17461.0195.4177.0691.121e-117.327e-1115.411746DLX2distal-less homeobox 2ENSG00000115844126255
181.465.01916.661.877e-441.145e-4290.3218ABAT4-aminobutyrate aminotransferaseENSG00000183044137150, 613163
20340.878510.2311.867.785e-271.512e-2549.952034EPAS1endothelial PAS domain protein 1ENSG00000116016603349, 611783
21810.946410.3416.622.596e-441.559e-4289.992181ACSL3acyl-CoA synthetase long-chain family member 3ENSG00000123983602371
22640.83565.9178.3672.343e-152.068e-1423.752264FGFR4fibroblast growth factor receptor 4ENSG00000160867134935
229940.70845.910.48.243e-221.173e-2038.4622994AZI15-azacytidine induced 1ENSG00000141577613479
230530.91969.30411.064.905e-248.082e-2343.5523053KIAA0913KIAA0913ENSG00000214655NA
230890.68410.588.091.545e-141.273e-1321.8923089PEG10paternally expressed 10ENSG00000242265609810
232081.2335.09814.916.479e-382.51e-3675.3323208SYT11synaptotagmin XIENSG00000132718608741
233480.95197.80611.732.385e-264.491e-2548.8423348DOCK9dedicator of cytokinesis 9ENSG00000088387607325
234000.91266.5929.0981.375e-171.464e-1628.8323400ATP13A2ATPase type 13A2ENSG00000159363606693, 610513
235540.63586.8326.8723.732e-112.332e-1014.2323554TSPAN12tetraspanin 12ENSG00000106025613138, 613310
24137-0.63259.497-15.921.095e-415.445e-4083.9724137KIF4Akinesin family member 4AENSG00000090889300521
25391.0759.01710.371.028e-211.455e-2038.242539G6PDglucose-6-phosphate dehydrogenaseENSG00000160211305900
260351.5925.86820.961.676e-602.829e-58127.126035GLCEglucuronic acid epimeraseENSG00000138604612134
270741.3497.0613.923.09e-349.339e-3366.8927074LAMP3lysosomal-associated membrane protein 3ENSG00000078081605883
27600.581810.047.791.134e-138.729e-1319.932760GM2AGM2 ganglioside activatorENSG00000196743272750, 613109
27661.6655.49724.378.53e-733.585e-70155.32766GMPRguanosine monophosphate reductaseENSG00000137198139265
27990.48658.6848.6393.575e-163.383e-1525.612799GNSglucosamine (N-acetyl)-6-sulfataseENSG00000135677252940, 607664
29340.757.7839.7511.142e-191.41e-1833.572934GSNgelsolinENSG00000148180105120, 137350
30051.22510.8714.599.825e-373.502e-3572.623005H1F0H1 histone family, member 0ENSG00000189060142708
32800.72369.17.8935.74e-144.519e-1320.63280HES1hairy and enhancer of split 1, (Drosophila)ENSG00000114315139605
33061.4597.5117.191.947e-461.368e-4494.873306HSPA2heat shock 70kDa protein 2ENSG00000126803140560
332-0.3259.831-7.6213.423e-132.538e-1218.84332BIRC5baculoviral IAP repeat containing 5ENSG00000089685603352
3340.466311.137.8358.422e-146.535e-1320.22334APLP2amyloid beta (A4) precursor-like protein 2ENSG00000084234104776
33981.5788.11215.533.12e-401.401e-3880.643398ID2inhibitor of DNA binding 2, dominant negative helix-loop-helix proteinENSG00000115738600386
34220.76679.23115.572.217e-401.01e-3880.983422IDI1isopentenyl-diphosphate delta isomerase 1ENSG00000067064604055
36210.7828.33314.472.94e-361.014e-3471.533621ING1inhibitor of growth family, member 1ENSG00000153487275355, 601566
36550.674110.349.9073.543e-204.492e-1934.733655ITGA6integrin, alpha 6ENSG00000091409147556, 226730
37260.92848.47411.511.398e-252.525e-2447.083726JUNBjun B proto-oncogeneENSG00000171223165161
3842.1565.74226.435.725e-803.447e-77171.8384ARG2arginase, type IIENSG00000081181107830
39930.9757.08313.344.033e-321.085e-3062.053993LLGL2lethal giant larvae homolog 2 (Drosophila)ENSG00000073350NA
42081.6976.49615.456.646e-402.926e-3879.884208MEF2Cmyocyte enhancer factor 2CENSG00000081189600662, 613443
42911.7318.82822.822.854e-677.419e-65142.74291MLF1myeloid leukemia factor 1ENSG00000178053601402, 601626
4487-0.83546.333-7.9444.105e-143.287e-1320.934487MSX1msh homeobox 1ENSG00000163132106600, 142983, 189500, 608874
46500.72696.4637.381.597e-121.119e-1117.324650MYO9Bmyosin IXBENSG00000099331602129, 609753
47391.4426.00419.977.792e-571.072e-54118.74739NEDD9neural precursor cell expressed, developmentally down-regulated 9ENSG00000111859602265
47581.5148.30320.151.651e-572.343e-55120.34758NEU1sialidase 1 (lysosomal sialidase)ENSG00000234343, ENSG00000228691, ENSG00000204386, ENSG00000227315, ENSG00000227129, ENSG00000234846, ENSG00000223957, ENSG00000184494256550, 608272
49020.48794.5897.0811.041e-116.824e-1115.484902NRTNneurturinENSG00000171119142623, 602018
49290.81935.04313.585.404e-331.522e-3164.054929NR4A2nuclear receptor subfamily 4, group A, member 2ENSG00000153234168600, 601828
513471.9678.07223.412.143e-696.281e-67147.551347TAOK3TAO kinase 3ENSG00000135090NA
51570.59045.3697.9224.746e-143.775e-1320.795157PDGFRLplatelet-derived growth factor receptor-likeENSG00000104213114500, 114550, 604584
51680.46064.2157.6652.56e-131.914e-1219.135168ENPP2ectonucleotide pyrophosphatase/phosphodiesterase 2ENSG00000136960601060
52742.4075.43916.516.956e-444.014e-4289.015274SERPINI1serpin peptidase inhibitor, clade I (neuroserpin), member 1ENSG00000163536602445, 604218
52931.2327.38912.987.944e-311.991e-2959.085293PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptideENSG00000171608602839
54471.0947.71310.931.394e-232.24e-2242.515447PORP450 (cytochrome) oxidoreductaseENSG00000127948124015, 201750, 613571
54931.76.72514.675.202e-371.891e-3573.255493PPLperiplakinENSG00000118898602871
555581.0344.97311.316.565e-251.148e-2345.5455558PLXNA3plexin A3ENSG00000130827300022
555890.66256.1017.5375.857e-134.252e-1218.3155589BMP2KBMP2 inducible kinaseENSG00000138756NA
557400.566510.149.9682.249e-202.905e-1935.1855740ENAHenabled homolog (Drosophila)ENSG00000154380609061
557660.55584.7049.0372.122e-172.221e-1628.455766H2AFJH2A histone family, member JENSG00000246705NA
55771.544.82614.73.818e-371.404e-3573.565577PRKAR2Bprotein kinase, cAMP-dependent, regulatory, type II, betaENSG00000005249176912
56300.66185.748.5427.004e-166.504e-1524.955630PRPHperipherinENSG00000135406105400, 170710
57341.868.30414.386.08e-362.077e-3470.85734PTGER4prostaglandin E receptor 4 (subtype EP4)ENSG00000171522601586
577281.7117.26923.249.231e-692.613e-66146.157728WDR19WD repeat domain 19ENSG00000157796608151, 614376, 614377, 614378
58831.0847.0411.279.07e-251.565e-2345.225883RAD9ARAD9 homolog A (S. pombe)ENSG00000172613603761
6041.9288.71316.863.443e-452.185e-4392.01604BCL6B-cell CLL/lymphoma 6ENSG00000113916109565
62531.2175.6214.656.272e-372.268e-3573.076253RTN2reticulon 2ENSG00000125744603183
63050.48425.5257.8527.523e-145.868e-1320.336305SBF1SET binding factor 1ENSG00000100241603560
63221.2858.77114.531.65e-365.754e-3572.16322SCML1sex comb on midleg-like 1 (Drosophila)ENSG00000047634300227
63850.86499.75615.456.589e-402.907e-3879.896385SDC4syndecan 4ENSG00000124145600017
64140.96965.0927.2443.771e-122.565e-1116.486414SEPP1selenoprotein P, plasma, 1ENSG00000250722601484
64571.4347.26414.561.293e-364.558e-3572.346457SH3GL3SH3-domain GRB2-like 3ENSG00000140600603362
65481.0978.51913.093.244e-318.268e-3059.976548SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), member 1ENSG00000090020107310
66241.2539.8867.0341.39e-119.008e-1115.26624FSCN1fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)ENSG00000075618602689
67720.61219.8712.494.508e-291.008e-2755.076772STAT1signal transducer and activator of transcription 1, 91kDaENSG00000115415209950, 600555, 613796, 614162
7153-0.78959.628-12.78.194e-301.924e-2856.767153TOP2Atopoisomerase (DNA) II alpha 170kDaENSG00000131747126430
7205-0.98667.294-8.4251.575e-151.418e-1424.157205TRIP6thyroid hormone receptor interactor 6ENSG00000087077602933
72862.2579.23716.441.269e-437.084e-4288.417286TUFT1tuftelin 1ENSG00000143367600087
74140.438312.7415.552.753e-401.241e-3880.767414VCLvinculinENSG00000035403193065, 611407, 613255
791451.2957.41812.862.278e-305.539e-2958.0479145CHCHD7coiled-coil-helix-coiled-coil-helix domain containing 7ENSG00000170791611238
818940.47566.7167.5794.484e-133.288e-1218.5781894SLC25A28solute carrier family 25, member 28ENSG00000155287609767
82021.4887.43817.549.767e-487.301e-4697.858202NCOA3nuclear receptor coactivator 3ENSG00000124151601937
83340.456210.257.0511.254e-118.157e-1115.38334HIST1H2AChistone cluster 1, H2acENSG00000180573602794
83571.3856.67812.717.746e-301.824e-2856.828357HIST1H3Hhistone cluster 1, H3hENSG00000198366, ENSG00000124693, ENSG00000196532, ENSG00000197409, ENSG00000196966, ENSG00000256316, ENSG00000256018, ENSG00000203813, ENSG00000182572, ENSG00000197153602818
836041.1396.1658.5835.286e-164.952e-1525.2283604TMEM47transmembrane protein 47ENSG00000147027300698
86231.6926.62122.78.141e-671.993e-64141.68623ASMTLacetylserotonin O-methyltransferase-likeENSG00000169093300162, 400011
86590.74895.5836.972.06e-111.319e-1014.818659ALDH4A1aldehyde dehydrogenase 4 family, member A1ENSG00000159423239510, 606811
88410.7089.00815.832.435e-411.179e-3983.188841HDAC3histone deacetylase 3ENSG00000171720605166
8913-0.54134.667-9.5057.095e-198.275e-1831.778913CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunitENSG00000006283604065
89251.2738.7416.526.381e-443.702e-4289.18925HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1ENSG00000103657605109
89361.1338.38318.31.311e-501.154e-48104.48936WASF1WAS protein family, member 1ENSG00000112290605035
89711.7078.83918.954.932e-535.466e-511108971H1FXH1 histone family, member XENSG00000184897602785
90430.759310.3913.054.355e-311.106e-2959.689043SPAG9sperm associated antigen 9ENSG00000008294605430
92610.57639.7679.3282.589e-182.89e-1730.489261MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2ENSG00000162889602006
928150.66397.9110.774.661e-237.176e-2241.3192815HIST3H2Ahistone cluster 3, H2aENSG00000181218NA
96591.2615.1112.611.702e-293.922e-2856.049659PDE4DIPphosphodiesterase 4D interacting proteinENSG00000178104608117
98140.55265.4048.4021.85e-151.653e-1423.999814SFI1Sfi1 homolog, spindle assembly associated (yeast)ENSG00000198089612765