Test Results

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Gene Set Null EGF receptor (ErbB1) signaling pathway

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10253-0.88267.949-13.741.326e-333.877e-3265.4510253SPRY2sprouty homolog 2 (Drosophila)ENSG00000136158602466
10261.6668.00412.533.319e-297.521e-2855.371026CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)ENSG00000124762116899
104581.7585.61820.594.026e-596.361e-5712410458BAIAP2BAI1-associated protein 2ENSG00000175866605475
10468-3.6639.442-38.423.427e-1171.272e-113256.910468FSTfollistatinENSG00000134363136470, 184700
10524-1.1877.19-18.031.371e-491.166e-47102.110524KAT5K(lysine) acetyltransferase 5ENSG00000172977601409
105800.96034.63414.051.006e-343.162e-3368.0110580SORBS1sorbin and SH3 domain containing 1ENSG00000095637605264
112212.3526.05914.116.012e-351.927e-3368.5211221DUSP10dual specificity phosphatase 10ENSG00000143507608867
11241.0375.36415.842.24e-411.09e-3983.261124CHN2chimerin (chimaerin) 2ENSG00000106069602857
112610.697511.5814.463.078e-361.058e-3471.4811261CHPcalcium binding protein P22ENSG00000187446606988
1387-1.9598.584-22.331.724e-653.919e-63138.61387CREBBPCREB binding proteinENSG00000005339180849, 600140
1453-1.0239.618-25.691.979e-771.102e-741661453CSNK1Dcasein kinase 1, deltaENSG00000141551600864
1457-0.66279.992-15.494.55e-402.019e-3880.261457CSNK2A1casein kinase 2, alpha 1 polypeptideENSG00000101266115440
1541.5258.75915.428.295e-403.623e-3879.66154ADRB2adrenergic, beta-2-, receptor, surfaceENSG00000169252109690, 600807, 601665
18471.9348.87212.78.306e-301.948e-2856.751847DUSP5dual specificity phosphatase 5ENSG00000138166603069
1850.91354.5311.298.126e-251.408e-2345.33185AGTR1angiotensin II receptor, type 1ENSG00000144891106165, 145500, 267430
1871-1.4358.431-16.498.347e-444.78e-4288.831871E2F3E2F transcription factor 3ENSG00000112242600427
19591.1664.8112.671.037e-292.412e-2856.531959EGR2early growth response 2ENSG00000122877129010, 145900, 605253, 607678
20591.1539.38814.811.606e-376.053e-3674.422059EPS8epidermal growth factor receptor pathway substrate 8ENSG00000151491600206
22943-0.595813.09-14.511.96e-366.8e-3571.9322943DKK1dickkopf 1 homolog (Xenopus laevis)ENSG00000107984605189
23080.95865.92711.412.961e-255.272e-2446.332308FOXO1forkhead box O1ENSG00000150907136533, 268220
230921.7126.08924.321.238e-725.108e-7015523092ARHGAP26Rho GTPase activating protein 26ENSG00000145819605370, 607785
233031.4846.59918.281.619e-501.415e-48104.223303KIF13Bkinesin family member 13BENSG00000197892607350
23530.68064.87310.48.143e-221.161e-2038.472353FOSFBJ murine osteosarcoma viral oncogene homologENSG00000170345164810
25342.0546.26818.945.392e-535.917e-51109.92534FYNFYN oncogene related to SRC, FGR, YESENSG00000010810137025
258052.9437.10434.371.815e-1055.054e-102230.125805BAMBIBMP and activin membrane-bound inhibitor homolog (Xenopus laevis)ENSG00000095739604444
25898-1.5498.447-193.303e-533.698e-51110.425898RCHY1ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligaseENSG00000163743607680
27701.9287.5927.422.541e-831.826e-80179.52770GNAI1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1ENSG00000127955139310
289841.2085.13615.621.428e-406.6e-3981.4228984RGCCregulator of cell cycleENSG00000102760610077
3171.1696.94715.244.027e-391.655e-3778.09317APAF1apoptotic peptidase activating factor 1ENSG00000120868602233
33030.807112.18141.551e-344.767e-3367.583303HSPA1Aheat shock 70kDa protein 1AENSG00000234475, ENSG00000231555, ENSG00000235941, ENSG00000232804, ENSG00000204389, ENSG00000204388, ENSG00000237724, ENSG00000224501, ENSG00000215328, ENSG00000212866140550
3566-1.0316.104-10.399.29e-221.32e-2038.343566IL4Rinterleukin 4 receptorENSG00000077238147050, 147781, 609423
3603.5265.58928.796.598e-889.011e-85190360AQP3aquaporin 3 (Gill blood group)ENSG00000165272600170, 607457
3663-0.58355.616-10.542.789e-224.103e-2139.543663IRF5interferon regulatory factor 5ENSG00000128604607218, 612245, 612251
3667-1.3577.989-12.651.229e-292.844e-2856.363667IRS1insulin receptor substrate 1ENSG00000169047125853, 147545
37260.92848.47411.511.398e-252.525e-2447.083726JUNBjun B proto-oncogeneENSG00000171223165161
3837-0.750711.65-18.321.072e-509.479e-49104.63837KPNB1karyopherin (importin) beta 1ENSG00000108424602738
3976-2.6177.137-21.541.28e-622.437e-601323976LIFleukemia inhibitory factorENSG00000128342159540
4086-1.3057.049-14.571.189e-364.212e-3572.434086SMAD1SMAD family member 1ENSG00000170365601595
41371.0474.88712.872.079e-305.072e-2958.134137MAPTmicrotubule-associated protein tauENSG00000257437, ENSG00000186868157140, 168600, 172700, 260540, 600274, 601104
42081.6976.49615.456.646e-402.926e-3879.884208MEF2Cmyocyte enhancer factor 2CENSG00000081189600662, 613443
4216-1.0587.796-13.962.22e-346.748e-3367.224216MAP3K4mitogen-activated protein kinase kinase kinase 4ENSG00000085511602425
42860.98387.08914.646.575e-372.374e-3573.024286MITFmicrophthalmia-associated transcription factorENSG00000187098103470, 103500, 156845, 193510
46031.5499.26116.931.867e-451.22e-4392.614603MYBL1v-myb myeloblastosis viral oncogene homolog (avian)-like 1ENSG00000185697159405
466-1.4268.875-141.544e-344.752e-3367.58466ATF1activating transcription factor 1ENSG00000123268123803
4790-0.93617.776-14.723.449e-371.27e-3573.664790NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1ENSG00000109320164011
4802-1.5567.396-19.552.902e-553.612e-53115.14802NFYCnuclear transcription factor Y, gammaENSG00000066136605344
513471.9678.07223.412.143e-696.281e-67147.551347TAOK3TAO kinase 3ENSG00000135090NA
5284-0.50754.612-11.811.235e-262.378e-2549.495284PIGRpolymeric immunoglobulin receptorENSG00000162896161950, 173880
5329-0.98749.122-15.051.963e-387.769e-3776.515329PLAURplasminogen activator, urokinase receptorENSG00000011422173391
5347-1.5518.164-18.647.134e-527.063e-50107.35347PLK1polo-like kinase 1ENSG00000166851602098
53662.1628.08323.461.457e-694.447e-67147.95366PMAIP1phorbol-12-myristate-13-acetate-induced protein 1ENSG00000141682604959
53710.60735.90210.671.008e-221.519e-2140.555371PMLpromyelocytic leukemiaENSG00000140464102578
54487-0.86925.544-10.881.992e-233.156e-2242.1654487DGCR8DiGeorge syndrome critical region gene 8ENSG00000128191609030
545411.3727.55612.611.702e-293.922e-2856.0454541DDIT4DNA-damage-inducible transcript 4ENSG00000168209607729
55300.58359.44914.154.304e-351.392e-3368.865530PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozymeENSG00000138814114105
55781.0667.31315.012.848e-381.123e-3676.145578PRKCAprotein kinase C, alphaENSG00000154229176960
55801.757.47819.717.303e-569.458e-54116.55580PRKCDprotein kinase C, deltaENSG00000163932176977
55830.85398.55511.241.145e-241.961e-2344.995583PRKCHprotein kinase C, etaENSG00000027075601367, 605437
56061.7389.05817.046.833e-464.613e-4493.625606MAP2K3mitogen-activated protein kinase kinase 3ENSG00000034152602315
57701.2098.30812.78e-301.88e-2856.795770PTPN1protein tyrosine phosphatase, non-receptor type 1ENSG00000196396125853, 176885
5771-0.889410.27-12.911.463e-303.622e-2958.485771PTPN2protein tyrosine phosphatase, non-receptor type 2ENSG00000175354176887
58190-1.2028.574-20.574.732e-597.424e-57123.858190CTDSP1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1ENSG00000144579605323
59080.371811.2510.765.242e-238.031e-2241.25908RAP1BRAP1B, member of RAS oncogene familyENSG00000127314179530
598-1.0619.808-13.643.249e-339.279e-3264.55598BCL2L1BCL2-like 1ENSG00000171552600039
6041.9288.71316.863.443e-452.185e-4392.01604BCL6B-cell CLL/lymphoma 6ENSG00000113916109565
6249-1.4728.836-23.286.266e-691.813e-66146.56249CLIP1CAP-GLY domain containing linker protein 1ENSG00000130779179838
6541.3624.75616.981.209e-457.99e-4493.05654BMP6bone morphogenetic protein 6ENSG00000153162112266
65481.0978.51913.093.244e-318.268e-3059.976548SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), member 1ENSG00000090020107310
65911.0849.29110.427.303e-221.046e-2038.586591SNAI2snail homolog 2 (Drosophila)ENSG00000019549172800, 602150, 608890
66480.97378.17418.889.23e-539.933e-51109.46648SOD2superoxide dismutase 2, mitochondrialENSG00000112096147460, 612634
67720.61219.8712.494.508e-291.008e-2755.076772STAT1signal transducer and activator of transcription 1, 91kDaENSG00000115415209950, 600555, 613796, 614162
6880-0.70849.616-10.371.02e-211.445e-2038.256880TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDaENSG00000085231600822
68850.67157.88911.374.11e-257.267e-2446.016885MAP3K7mitogen-activated protein kinase kinase kinase 7ENSG00000135341602614
70741.4018.0115.83.184e-411.529e-3982.917074TIAM1T-cell lymphoma invasion and metastasis 1ENSG00000156299600687
71591.078.58618.414.995e-514.505e-49105.47159TP53BP2tumor protein p53 binding protein, 2ENSG00000143514602143
74140.438312.7415.552.753e-401.241e-3880.767414VCLvinculinENSG00000035403193065, 611407, 613255
7514-0.773211.74-24.611.202e-735.952e-71157.37514XPO1exportin 1 (CRM1 homolog, yeast)ENSG00000082898602559
7528-0.647311.26-15.911.244e-416.159e-4083.857528YY1YY1 transcription factorENSG00000100811600013
7533-0.96818.591-10.311.715e-212.385e-2037.747533YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptideENSG00000128245113508
7874-0.80169.385-12.061.539e-273.116e-2651.567874USP7ubiquitin specific peptidase 7 (herpes virus-associated)ENSG00000187555602519
8061-1.67811.23-19.651.205e-551.534e-531168061FOSL1FOS-like antigen 1ENSG00000175592136515
8180.61910.0712.176.316e-281.303e-2652.44818CAMK2Gcalcium/calmodulin-dependent protein kinase II gammaENSG00000148660602123
8295-0.65078.766-10.53.98e-225.768e-2139.188295TRRAPtransformation/transcription domain-associated proteinENSG00000196367603015
84080.97947.3111.064.695e-247.754e-2343.598408ULK1unc-51-like kinase 1 (C. elegans)ENSG00000177169603168
8420.93048.25316.265.713e-433.067e-4186.91842CASP9caspase 9, apoptosis-related cysteine peptidaseENSG00000132906602234
84271-0.87698.157-12.272.938e-286.221e-2753.284271POLDIP3polymerase (DNA-directed), delta interacting protein 3ENSG00000100227611520
85690.57988.53910.921.462e-232.341e-2242.468569MKNK1MAP kinase interacting serine/threonine kinase 1ENSG00000079277606724
86601.7137.08516.323.578e-431.949e-4187.388660IRS2insulin receptor substrate 2ENSG00000185950125853, 600797
8681.0798.4917.065.842e-463.968e-4493.77868CBLBCbl proto-oncogene, E3 ubiquitin protein ligase BENSG00000114423604491
87950.9659.9612.485.047e-291.124e-2754.968795TNFRSF10Btumor necrosis factor receptor superfamily, member 10bENSG00000120889275355, 603612
88670.94187.7311.791.454e-262.773e-2549.338867SYNJ1synaptojanin 1ENSG00000159082604297
890-0.90148.733-14.311.106e-353.715e-3470.21890CCNA2cyclin A2ENSG00000145386123835
891-0.763910.69-19.543.175e-553.929e-53115891CCNB1cyclin B1ENSG00000134057123836
9000.450810.7111.944.062e-277.994e-2650.59900CCNG1cyclin G1ENSG00000113328601578
90430.759310.3913.054.355e-311.106e-2959.689043SPAG9sperm associated antigen 9ENSG00000008294605430
9266-0.99427.305-15.49.563e-404.169e-3879.529266CYTH2cytohesin 2ENSG00000105443602488
92670.96457.15110.746.239e-239.521e-2241.029267CYTH1cytohesin 1ENSG00000108669182115
94670.96999.37212.997.622e-311.914e-2959.129467SH3BP5SH3-domain binding protein 5 (BTK-associated)ENSG00000131370605612
98150.96317.52410.533.105e-224.542e-2139.439815GIT2G protein-coupled receptor kinase interacting ArfGAP 2ENSG00000139436608564
98210.91367.23812.138.894e-281.819e-2652.19821RB1CC1RB1-inducible coiled-coil 1ENSG00000023287114480, 606837