Test Results

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Gene Set Broad PEREZ_TP53_TARGETS

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
100141.1976.32615.292.451e-396.757e-3878.5210014HDAC5histone deacetylase 5ENSG00000108840605315
100190.72788.29115.641.237e-403.66e-3981.510019SH2B3SH2B adaptor protein 3ENSG00000111252133100, 187950, 222100, 254450, 605093, 612011
10262.4678.00418.261.938e-509.553e-491041026CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)ENSG00000124762116899
10280.73674.93212.41.011e-281.563e-2754.191028CDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2)ENSG00000129757130650, 600856
104582.3245.61826.773.88e-811.351e-78174.510458BAIAP2BAI1-associated protein 2ENSG00000175866605475
104611.8434.82227.644.662e-841.997e-81181.210461MERTKc-mer proto-oncogene tyrosine kinaseENSG00000153208268000, 604705, 613862
105701.6346.81812.862.168e-303.707e-2958.0110570DPYSL4dihydropyrimidinase-like 4ENSG00000151640608407
109780.60149.58413.585.409e-331.062e-3163.9810978CLP1CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)ENSG00000172409608757
11083-1.257.953-14.96.9e-381.749e-3675.211083DIDO1death inducer-obliterator 1ENSG00000101191604140
11191.8197.57819.591.946e-551.363e-53115.51119CHKAcholine kinase alphaENSG00000110721118491
1131461.5718.57413.422.065e-323.912e-3162.64113146AHNAK2AHNAK nucleoprotein 2ENSG00000185567608570
1151231.2535.29211.95.851e-278.303e-2650.15115123MARCH3membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligaseENSG00000173926613333
12410.96334.72814.74.11e-371.003e-3573.421241LTB4Rleukotriene B4 receptorENSG00000213903601531
1262981.1167.43715.131.037e-382.756e-3777.09126298IRGQimmunity-related GTPase family, QENSG00000167378NA
1541.9358.75919.253.737e-542.358e-52112.5154ADRB2adrenergic, beta-2-, receptor, surfaceENSG00000169252109690, 600807, 601665
1624270.94578.1612.793.813e-306.42e-2957.45162427FAM134Cfamily with sequence similarity 134, member CENSG00000141699NA
17892.1196.60230.684.814e-944.469e-91204.11789DNMT3BDNA (cytosine-5-)-methyltransferase 3 betaENSG00000088305242860, 602900
19451.2076.75712.331.696e-282.6e-2753.671945EFNA4ephrin-A4ENSG00000243364601380
19591.9214.8120.555.836e-595.039e-57123.61959EGR2early growth response 2ENSG00000122877129010, 145900, 605253, 607678
2000-1.148.83-15.861.844e-415.674e-4083.42000ELF4E74-like factor 4 (ets domain transcription factor)ENSG00000102034300775
20491.8166.80519.793.722e-562.709e-54117.12049EPHB3EPH receptor B3ENSG00000182580601839
2196541.5199.96427.732.199e-849.997e-82181.9219654ZCCHC24zinc finger, CCHC domain containing 24ENSG00000165424NA
22610.76494.29113.451.636e-323.107e-3162.872261FGFR3fibroblast growth factor receptor 3ENSG00000068078100800, 109800, 114500, 134934, 146000, 149730, 162900, 187600, 187601, 273300, 602849, 603956, 610474, 612247
229111.4648.22514.321.046e-352.404e-3470.222911WDR47WD repeat domain 47ENSG00000085433NA
229440.73137.49913.171.596e-312.895e-3060.6122944KINKIN, antigenic determinant of recA protein homolog (mouse)ENSG00000151657601720
230301.5476.89717.614.907e-482.173e-4698.4923030KDM4Blysine (K)-specific demethylase 4BENSG00000127663609765
230331.1796.85113.314.948e-329.185e-3161.7723033DOPEY1dopey family member 1ENSG00000083097NA
231741.4937.69316.691.392e-444.978e-4390.5623174ZCCHC14zinc finger, CCHC domain containing 14ENSG00000140948NA
232371.1194.54314.31.248e-352.851e-3470.0223237ARCactivity-regulated cytoskeleton-associated proteinENSG00000198576612461
236251.0318.70815.148.969e-392.39e-3777.2323625FAM89Bfamily with sequence similarity 89, member BENSG00000176973NA
23774-1.2497.536-15.447.103e-402.018e-3879.7623774BRD1bromodomain containing 1ENSG00000100425604589
25341.5848.72519.78.022e-565.728e-54116.42534FYNFYN oncogene related to SRC, FGR, YESENSG00000010810137025
258412.1976.18929.311.324e-898.193e-87193.925841ABTB2ankyrin repeat and BTB (POZ) domain containing 2ENSG00000166016NA
258611.2885.20815.735.679e-411.698e-3982.2725861DFNB31deafness, autosomal recessive 31ENSG00000095397607084, 607928, 611383
2592170.7854.48714.463.099e-367.274e-3571.41259217HSPA12Aheat shock 70kDa protein 12AENSG00000165868610701
269991.1075.33212.148.219e-281.219e-2652.126999CYFIP2cytoplasmic FMR1 interacting protein 2ENSG00000055163606323
27670.60928.6712.736.38e-301.057e-2856.942767GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)ENSG00000088256139313
28691.4346.00317.028.055e-463.074e-4493.42869GRK5G protein-coupled receptor kinase 5ENSG00000198873600870
29969-1.0319.175-14.964.38e-381.124e-3675.6529969MDFICMyoD family inhibitor domain containingENSG00000135272614511
30290.66518.16713.789.549e-341.966e-3265.73029HAGHhydroxyacylglutathione hydrolaseENSG00000063854138760, 614033
31041.3386.78314.173.774e-358.407e-3468.923104ZBTB48zinc finger and BTB domain containing 48ENSG00000204859165270
3149-1.4269.851-21.732.538e-632.813e-61133.63149HMGB3high mobility group box 3ENSG00000029993300193
35561.5376.71818.473.03e-511.592e-49105.93556IL1RAPinterleukin 1 receptor accessory proteinENSG00000196083602626
3604.6765.58937.568.56e-1152.724e-111251.6360AQP3aquaporin 3 (Gill blood group)ENSG00000165272600170, 607457
3652-1.2576.693-17.643.908e-481.741e-4698.713652IPPintracisternal A particle-promoted polypeptideENSG00000197429147485
3707-1.067.107-12.391.043e-281.609e-2754.163707ITPKBinositol-trisphosphate 3-kinase BENSG00000143772147522
37261.38.47415.852.01e-416.16e-4083.313726JUNBjun B proto-oncogeneENSG00000171223165161
3842.5145.74230.336.327e-935.421e-90201.5384ARG2arginase, type IIENSG00000081181107830
3881.8247.22714.665.682e-371.376e-3573.1388RHOBras homolog family member BENSG00000143878165370
39951.0236.85813.373.184e-325.971e-3162.213995FADS3fatty acid desaturase 3ENSG00000221968606150
3996651.5076.74621.674.237e-634.604e-61133.1399665FAM102Afamily with sequence similarity 102, member AENSG00000167106610891
4088-1.079.531-22.381.09e-651.395e-631394088SMAD3SMAD family member 3ENSG00000166949603109, 613795
41261.2856.89215.494.505e-401.302e-3880.214126MANBAmannosidase, beta A, lysosomalENSG00000109323248510, 609489
46010.92229.10116.951.551e-455.788e-4492.754601MXI1MAX interactor 1ENSG00000119950176807, 600020
46511.0049.61313.064.221e-317.469e-3059.644651MYO10myosin XENSG00000145555601481
47391.6276.00422.167.184e-658.746e-63137.14739NEDD9neural precursor cell expressed, developmentally down-regulated 9ENSG00000111859602265
506491.0835.27112.428.61e-291.338e-2754.3550649ARHGEF4Rho guanine nucleotide exchange factor (GEF) 4ENSG00000136002605216
544630.90385.20713.13.067e-315.462e-3059.9654463FAM134Bfamily with sequence similarity 134, member BENSG00000154153613114, 613115
548550.79714.87412.121.002e-271.479e-2651.9154855FAM46Cfamily with sequence similarity 46, member CENSG00000183508613952
550571.0964.71315.391.098e-393.085e-3879.3255057AIM1Labsent in melanoma 1-likeENSG00000176092NA
555210.91733.98917.442.269e-479.521e-4696.9655521TRIM36tripartite motif containing 36ENSG00000152503609317
555680.86488.60513.211.229e-312.242e-3060.8755568GALNT10UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)ENSG00000164574608043
55585-0.786510.62-19.253.621e-542.292e-52112.655585UBE2Q1ubiquitin-conjugating enzyme E2Q family member 1ENSG00000160714NA
557510.99238.33413.142.165e-313.905e-3060.355751TMEM184Ctransmembrane protein 184CENSG00000164168613937
561800.73599.63811.673.608e-264.898e-2548.3456180MOSPD1motile sperm domain containing 1ENSG00000101928300674
56623-0.8996.467-13.412.156e-324.08e-3162.656623INPP5Einositol polyphosphate-5-phosphatase, 72 kDaENSG00000148384213300, 610156, 613037
571340.91684.57918.145.241e-502.511e-4810357134MAN1C1mannosidase, alpha, class 1C, member 1ENSG00000117643NA
574061.4087.84420.816.194e-605.678e-58125.857406ABHD6abhydrolase domain containing 6ENSG00000163686NA
575531.4935.53614.954.78e-381.224e-3675.5657553MICAL3microtubule associated monoxygenase, calponin and LIM domain containing 3ENSG00000093100, ENSG00000243156608882
577871.2888.45616.043.905e-421.248e-4084.9457787MARK4MAP/microtubule affinity-regulating kinase 4ENSG00000007047606495
639160.72847.88613.556.982e-331.355e-3163.7263916ELMO2engulfment and cell motility 2ENSG00000062598606421
644001.0068.06211.742.117e-262.91e-2548.8764400AKTIPAKT interacting proteinENSG00000166971608483
647640.90559.18117.231.396e-465.542e-4595.1564764CREB3L2cAMP responsive element binding protein 3-like 2ENSG00000182158608834
648561.4545.16114.831.268e-373.177e-3674.5964856VWA1von Willebrand factor A domain containing 1ENSG00000179403611901
6877-1.0587.689-11.791.42e-261.969e-2549.276877TAF5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDaENSG00000148835601787
72862.5679.23718.45.807e-512.96e-49105.27286TUFT1tuftelin 1ENSG00000143367600087
7465-0.95378.652-13.991.672e-343.624e-3367.447465WEE1WEE1 homolog (S. pombe)ENSG00000166483193525
77981.3697.88919.784.022e-562.918e-54117.17798LUZP1leucine zipper protein 1ENSG00000169641601422
800130.89037.19114.821.412e-373.522e-3674.4880013FAM188Afamily with sequence similarity 188, member AENSG00000148481611649
815441.1017.29312.437.977e-291.242e-2754.4281544GDPD5glycerophosphodiester phosphodiesterase domain containing 5ENSG00000158555609632
81603-1.3189.544-19.456.84e-554.59e-53114.281603TRIM8tripartite motif containing 8ENSG00000171206606125
8180.841210.0716.285.174e-431.723e-4186.96818CAMK2Gcalcium/calmodulin-dependent protein kinase II gammaENSG00000148660602123
82181.225.69719.523.745e-552.559e-53114.88218CLTCL1clathrin, heavy chain-like 1ENSG00000070371601273
834812.8775.9119.224.851e-543.027e-52112.383481EPPK1epiplakin 1ENSG00000227184607553
837163.585.93429.571.872e-901.303e-87195.983716CRISPLD2cysteine-rich secretory protein LCCL domain containing 2ENSG00000103196612434
83759-1.478.117-22.911.416e-671.983e-65143.383759RBM4BRNA binding motif protein 4BENSG00000173914NA
84081.4157.3115.735.745e-411.716e-3982.268408ULK1unc-51-like kinase 1 (C. elegans)ENSG00000177169603168
84890-0.880311.03-236.417e-689.405e-66144.184890ADO2-aminoethanethiol (cysteamine) dioxygenaseENSG00000181915611392
84986-0.7957.218-14.059.856e-352.153e-3367.9684986ARHGAP19Rho GTPase activating protein 19ENSG00000213390611587
8837-1.6866.759-24.649.657e-742.068e-71157.58837CFLARCASP8 and FADD-like apoptosis regulatorENSG00000003402603599
89002.2726.30421.732.583e-632.848e-61133.68900CCNA1cyclin A1ENSG00000133101604036
90941.0786.63214.192.994e-356.716e-3469.159094UNC119unc-119 homolog (C. elegans)ENSG00000109103604011
91391.2727.31217.221.511e-465.977e-4595.079139CBFA2T2core-binding factor, runt domain, alpha subunit 2; translocated to, 2ENSG00000078699603672
9184-1.14610.2-27.644.45e-841.944e-81181.29184BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)ENSG00000154473603719
9231-0.470711.57-12.91.538e-302.651e-2958.359231DLG5discs, large homolog 5 (Drosophila)ENSG00000151208266600, 604090
94351.4657.13712.592.01e-293.223e-2855.799435CHST2carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2ENSG00000175040603798
96192.4365.15925.42.131e-765.519e-74163.69619ABCG1ATP-binding cassette, sub-family G (WHITE), member 1ENSG00000160179603076
96360.850910.5212.351.491e-282.289e-2753.89636ISG15ISG15 ubiquitin-like modifierENSG00000187608147571
97661.0788.04713.781.025e-332.107e-3265.639766KIAA0247KIAA0247ENSG00000100647NA
9891-1.2038.55-13.836.207e-341.295e-3266.139891NUAK1NUAK family, SNF1-like kinase, 1ENSG00000074590608130