Test Results

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Gene Set Null ErbB receptor signaling network

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10253-1.1527.949-17.663.469e-481.558e-4698.8310253SPRY2sprouty homolog 2 (Drosophila)ENSG00000136158602466
10262.4678.00418.261.938e-509.553e-491041026CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)ENSG00000124762116899
103971.43310.8113.171.721e-313.114e-3060.5310397NDRG1N-myc downstream regulated 1ENSG00000104419601455, 605262
10413-1.3138.131-16.526.428e-442.251e-4289.0410413YAP1Yes-associated protein 1ENSG00000137693606608
104582.3245.61826.773.88e-811.351e-78174.510458BAIAP2BAI1-associated protein 2ENSG00000175866605475
10468-3.5039.442-36.159.941e-1112.461e-107242.310468FSTfollistatinENSG00000134363136470, 184700
10511.28710.315.54.14e-401.199e-3880.291051CEBPBCCAAT/enhancer binding protein (C/EBP), betaENSG00000172216189965
10524-1.2527.19-18.713.792e-522.081e-50107.910524KAT5K(lysine) acetyltransferase 5ENSG00000172977601409
105801.224.63417.558.291e-483.615e-4697.9610580SORBS1sorbin and SH3 domain containing 1ENSG00000095637605264
1111-1.2488.88-12.543.088e-294.906e-2855.371111CHEK1checkpoint kinase 1ENSG00000149554603078
112211.1065.46512.736.593e-301.09e-2856.911221DUSP10dual specificity phosphatase 10ENSG00000143507608867
11241.1875.36417.837.455e-493.431e-47100.41124CHN2chimerin (chimaerin) 2ENSG00000106069602857
1387-2.1028.584-23.575.696e-709.194e-68148.81387CREBBPCREB binding proteinENSG00000005339180849, 600140
1453-1.2089.618-29.862.089e-911.604e-881981453CSNK1Dcasein kinase 1, deltaENSG00000141551600864
1457-0.74429.992-17.113.691e-461.44e-4494.181457CSNK2A1casein kinase 2, alpha 1 polypeptideENSG00000101266115440
1541.9358.75919.253.737e-542.358e-52112.5154ADRB2adrenergic, beta-2-, receptor, surfaceENSG00000169252109690, 600807, 601665
1851.3934.5316.931.865e-456.903e-4492.56185AGTR1angiotensin II receptor, type 1ENSG00000144891106165, 145500, 267430
1871-1.6398.431-18.531.761e-519.406e-50106.41871E2F3E2F transcription factor 3ENSG00000112242600427
19591.9214.8120.555.836e-595.039e-57123.61959EGR2early growth response 2ENSG00000122877129010, 145900, 605253, 607678
2033-1.5046.866-17.558.701e-483.779e-4697.912033EP300E1A binding protein p300ENSG00000100393114500, 180849, 602700, 613684
22943-0.932513.09-22.351.496e-651.893e-63138.722943DKK1dickkopf 1 homolog (Xenopus laevis)ENSG00000107984605189
23081.126.4812.832.877e-304.878e-2957.732308FOXO1forkhead box O1ENSG00000150907136533, 268220
230921.9816.08927.683.213e-841.432e-81181.623092ARHGAP26Rho GTPase activating protein 26ENSG00000145819605370, 607785
233031.7326.59920.981.422e-601.36e-58127.323303KIF13Bkinesin family member 13BENSG00000197892607350
233681.0896.18513.343.951e-327.377e-316223368PPP1R13Bprotein phosphatase 1, regulatory subunit 13BENSG00000088808606455
23531.0624.87315.967.591e-422.365e-4084.282353FOSFBJ murine osteosarcoma viral oncogene homologENSG00000170345164810
25341.5848.72519.78.022e-565.728e-54116.42534FYNFYN oncogene related to SRC, FGR, YESENSG00000010810137025
258052.8067.10432.245.767e-998.565e-96215.425805BAMBIBMP and activin membrane-bound inhibitor homolog (Xenopus laevis)ENSG00000095739604444
25898-1.6138.447-19.466.236e-554.197e-53114.325898RCHY1ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligaseENSG00000163743607680
27670.60928.6712.736.38e-301.057e-2856.942767GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)ENSG00000088256139313
27701.2477.5917.442.16e-479.114e-4697.012770GNAI1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1ENSG00000127955139310
289841.3255.13616.863.204e-451.176e-4392.0228984RGCCregulator of cell cycleENSG00000102760610077
29341.0047.78312.852.397e-304.086e-2957.912934GSNgelsolinENSG00000148180105120, 137350
31641.7565.72922.071.472e-641.753e-62136.43164NR4A1nuclear receptor subfamily 4, group A, member 1ENSG00000123358139139
3169-2.4626.701-18.571.287e-516.909e-50106.73169FOXA1forkhead box A1ENSG00000129514602294
33030.810112.1813.826.826e-341.418e-3266.043303HSPA1Aheat shock 70kDa protein 1AENSG00000234475, ENSG00000231555, ENSG00000235941, ENSG00000232804, ENSG00000204389, ENSG00000204388, ENSG00000237724, ENSG00000224501, ENSG00000215328, ENSG00000212866140550
3604.6765.58937.568.56e-1152.724e-111251.6360AQP3aquaporin 3 (Gill blood group)ENSG00000165272600170, 607457
3667-1.7887.989-16.41.817e-436.21e-42883667IRS1insulin receptor substrate 1ENSG00000169047125853, 147545
37261.38.47415.852.01e-416.16e-4083.313726JUNBjun B proto-oncogeneENSG00000171223165161
37910.60154.25612.592.125e-293.403e-2855.743791KDRkinase insert domain receptor (a type III receptor tyrosine kinase)ENSG00000128052191306, 602089
3836-0.6499.274-14.183.304e-357.389e-3469.053836KPNA1karyopherin alpha 1 (importin alpha 5)ENSG00000114030600686
3837-0.766411.65-18.415.241e-512.69e-49105.33837KPNB1karyopherin (importin) beta 1ENSG00000108424602738
3976-2.7997.137-22.671.035e-661.415e-64141.43976LIFleukemia inhibitory factorENSG00000128342159540
4086-1.8297.049-20.083.014e-572.331e-55119.64086SMAD1SMAD family member 1ENSG00000170365601595
41371.395.2820.112.292e-571.786e-55119.94137MAPTmicrotubule-associated protein tauENSG00000257437, ENSG00000186868157140, 168600, 172700, 260540, 600274, 601104
42151.0867.86914.068.91e-351.948e-3368.064215MAP3K3mitogen-activated protein kinase kinase kinase 3ENSG00000198909602539
42861.0417.08915.253.599e-399.814e-3878.144286MITFmicrophthalmia-associated transcription factorENSG00000187098103470, 103500, 156845, 193510
46031.549.26116.564.496e-441.585e-4289.394603MYBL1v-myb myeloblastosis viral oncogene homolog (avian)-like 1ENSG00000185697159405
466-1.6898.875-16.313.949e-431.327e-4187.23466ATF1activating transcription factor 1ENSG00000123268123803
4790-1.2747.776-19.717.256e-565.197e-54116.54790NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1ENSG00000109320164011
4802-1.2547.293-18.522.029e-511.079e-49106.34802NFYCnuclear transcription factor Y, gammaENSG00000066136605344
513472.0228.07223.682.368e-703.996e-68149.751347TAOK3TAO kinase 3ENSG00000135090NA
514741.8069.06315.224.538e-391.23e-3777.9151474LIMA1LIM domain and actin binding 1ENSG00000050405608364
52921.1455.95913.64.432e-338.729e-3264.175292PIM1pim-1 oncogeneENSG00000137193164960
5329-1.1419.122-17.113.966e-461.545e-4494.115329PLAURplasminogen activator, urokinase receptorENSG00000011422173391
5347-1.8568.164-21.954.245e-644.9e-62135.45347PLK1polo-like kinase 1ENSG00000166851602098
53661.4268.08315.224.47e-391.214e-3777.925366PMAIP1phorbol-12-myristate-13-acetate-induced protein 1ENSG00000141682604959
53710.75945.90213.132.273e-314.09e-3060.255371PMLpromyelocytic leukemiaENSG00000140464102578
545412.0147.55618.222.674e-501.306e-48103.754541DDIT4DNA-damage-inducible transcript 4ENSG00000168209607729
55300.5799.44913.817.406e-341.532e-3265.955530PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozymeENSG00000138814114105
55781.4387.31319.931.092e-568.22e-55118.45578PRKCAprotein kinase C, alphaENSG00000154229176960
55801.8547.47820.546.059e-595.191e-57123.55580PRKCDprotein kinase C, deltaENSG00000163932176977
56061.8618.22117.653.674e-481.643e-4698.775606MAP2K3mitogen-activated protein kinase kinase 3ENSG00000034152602315
57701.6878.30817.442.234e-479.389e-4696.975770PTPN1protein tyrosine phosphatase, non-receptor type 1ENSG00000196396125853, 176885
5771-1.08310.27-15.475.523e-401.583e-3880.015771PTPN2protein tyrosine phosphatase, non-receptor type 2ENSG00000175354176887
58190-1.4938.574-25.141.675e-754.146e-73161.558190CTDSP1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1ENSG00000144579605323
598-1.4289.808-18.079.273e-504.395e-48102.4598BCL2L1BCL2-like 1ENSG00000171552600039
6041.7478.71315.022.529e-386.581e-3776.2604BCL6B-cell CLL/lymphoma 6ENSG00000113916109565
6249-1.4118.836-21.973.529e-644.095e-62135.56249CLIP1CAP-GLY domain containing linker protein 1ENSG00000130779179838
64562.2135.03414.472.863e-366.734e-3571.496456SH3GL2SH3-domain GRB2-like 2ENSG00000107295604465
647981.6815.35716.228.102e-432.69e-4186.5164798DEPTORDEP domain containing MTOR-interacting proteinENSG00000155792612974
6521.6295.5614.52.209e-365.208e-3571.75652BMP4bone morphogenetic protein 4ENSG00000125378112262, 600625, 607932
6541.9174.75623.519.951e-701.595e-67148.3654BMP6bone morphogenetic protein 6ENSG00000153162112266
65481.6268.51919.081.614e-539.668e-52111.16548SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), member 1ENSG00000090020107310
657-0.75046.243-12.419.046e-291.403e-2754.3657BMPR1Abone morphogenetic protein receptor, type IAENSG00000107779158350, 174900, 601299, 610069, 612242
66481.0648.17420.295.3e-584.247e-56121.46648SOD2superoxide dismutase 2, mitochondrialENSG00000112096147460, 612634
67202.5987.31319.381.262e-548.296e-53113.66720SREBF1sterol regulatory element binding transcription factor 1ENSG00000072310184756
7027-0.601910.46-12.437.62e-291.187e-2754.477027TFDP1transcription factor Dp-1ENSG00000198176189902
70741.7338.0119.234.617e-542.889e-52112.37074TIAM1T-cell lymphoma invasion and metastasis 1ENSG00000156299600687
71590.8438.58614.271.52e-353.449e-3469.827159TP53BP2tumor protein p53 binding protein, 2ENSG00000143514602143
7323-0.416311.27-12.341.586e-282.434e-2753.747323UBE2D3ubiquitin-conjugating enzyme E2D 3ENSG00000109332602963
74140.463812.7416.191.121e-423.689e-4186.197414VCLvinculinENSG00000035403193065, 611407, 613255
7514-1.02611.74-32.121.358e-981.891e-95214.57514XPO1exportin 1 (CRM1 homolog, yeast)ENSG00000082898602559
7528-0.747911.26-18.088.688e-504.127e-48102.57528YY1YY1 transcription factorENSG00000100811600013
75382.0426.75921.22.178e-612.196e-59129.17538ZFP36zinc finger protein 36, C3H type, homolog (mouse)ENSG00000128016190700
7874-0.63549.717-15.158.618e-392.299e-3777.277874USP7ubiquitin specific peptidase 7 (herpes virus-associated)ENSG00000187555602519
8061-2.16511.23-24.938.883e-752.061e-72159.98061FOSL1FOS-like antigen 1ENSG00000175592136515
8180.841210.0716.285.174e-431.723e-4186.96818CAMK2Gcalcium/calmodulin-dependent protein kinase II gammaENSG00000148660602123
84081.4157.3115.735.745e-411.716e-3982.268408ULK1unc-51-like kinase 1 (C. elegans)ENSG00000177169603168
8421.0888.25318.723.696e-522.038e-50108842CASP9caspase 9, apoptosis-related cysteine peptidaseENSG00000132906602234
85540.72828.34312.641.312e-292.132e-2856.228554PIAS1protein inhibitor of activated STAT, 1ENSG00000033800603566
85690.99338.53918.415.309e-512.719e-49105.38569MKNK1MAP kinase interacting serine/threonine kinase 1ENSG00000079277606724
86602.3567.08522.081.438e-641.722e-62136.48660IRS2insulin receptor substrate 2ENSG00000185950125853, 600797
8680.93228.4914.512.034e-364.806e-3571.83868CBLBCbl proto-oncogene, E3 ubiquitin protein ligase BENSG00000114423604491
87951.2749.9616.219.376e-433.108e-4186.368795TNFRSF10Btumor necrosis factor receptor superfamily, member 10bENSG00000120889275355, 603612
890-0.91348.733-14.271.597e-353.619e-3469.78890CCNA2cyclin A2ENSG00000145386123835
891-0.856210.69-21.551.23e-621.305e-60132891CCNB1cyclin B1ENSG00000134057123836
90430.794910.3913.451.633e-323.104e-3162.889043SPAG9sperm associated antigen 9ENSG00000008294605430
92610.78839.76712.552.757e-294.391e-2855.489261MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2ENSG00000162889602006
9655-0.73626.871-12.755.56e-309.271e-2957.079655SOCS5suppressor of cytokine signaling 5ENSG00000171150607094