Test Results

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Gene Set Null TRAIL signaling pathway

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10261.6218.0049.4481.075e-182.911e-1731.591026CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)ENSG00000124762116899
10524-1.1087.19-13.044.959e-314.169e-2959.7210524KAT5K(lysine) acetyltransferase 5ENSG00000172977601409
105800.69284.6347.8527.505e-141.296e-1220.5910580SORBS1sorbin and SH3 domain containing 1ENSG00000095637605264
1111-1.2378.88-9.7848.929e-202.659e-1834.051111CHEK1checkpoint kinase 1ENSG00000149554603078
112610.464511.587.469.592e-131.476e-1118.0911261CHPcalcium binding protein P22ENSG00000187446606988
12630.70955.2868.121.256e-142.331e-1322.351263PLK3polo-like kinase 3ENSG00000173846602913
1387-2.0298.584-17.923.612e-491.437e-46101.21387CREBBPCREB binding proteinENSG00000005339180849, 600140
1390-0.51219.586-8.0072.683e-144.819e-1321.611390CREMcAMP responsive element modulatorENSG00000095794123812
1453-1.1089.618-21.561.073e-621.138e-59132.11453CSNK1Dcasein kinase 1, deltaENSG00000141551600864
1457-0.69439.992-12.572.392e-291.718e-2755.881457CSNK2A1casein kinase 2, alpha 1 polypeptideENSG00000101266115440
1541.5058.75911.791.467e-268.253e-2549.51154ADRB2adrenergic, beta-2-, receptor, surfaceENSG00000169252109690, 600807, 601665
15400.52695.5456.6191.694e-102.05e-0913.021540CYLDcylindromatosis (turban tumor syndrome)ENSG00000083799132700, 601606, 605018, 605041
18471.9898.87210.127.234e-212.412e-1936.531847DUSP5dual specificity phosphatase 5ENSG00000138166603069
1871-1.68.431-14.241.937e-352.495e-3369.791871E2F3E2F transcription factor 3ENSG00000112242600427
19590.79334.816.6811.172e-101.443e-0913.381959EGR2early growth response 2ENSG00000122877129010, 145900, 605253, 607678
2033-0.78826.866-7.2393.891e-125.622e-1116.712033EP300E1A binding protein p300ENSG00000100393114500, 180849, 602700, 613684
22943-0.547513.09-10.331.421e-215.115e-2038.1422943DKK1dickkopf 1 homolog (Xenopus laevis)ENSG00000107984605189
23080.84186.487.5894.191e-136.678e-1218.92308FOXO1forkhead box O1ENSG00000150907136533, 268220
233031.2536.59911.963.571e-272.127e-2550.9123303KIF13Bkinesin family member 13BENSG00000197892607350
25341.3348.72513.064.076e-313.466e-2959.912534FYNFYN oncogene related to SRC, FGR, YESENSG00000010810137025
25898-1.6058.447-15.243.77e-396.772e-3778.2725898RCHY1ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligaseENSG00000163743607680
25998-0.7628.871-7.9055.314e-149.248e-1320.9325998IBTKinhibitor of Bruton agammaglobulinemia tyrosine kinaseENSG00000005700606457
27670.3978.676.5332.792e-103.296e-0912.532767GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)ENSG00000088256139313
289840.98745.1369.8983.804e-201.172e-1834.8928984RGCCregulator of cell cycleENSG00000102760610077
29340.75517.7837.6063.752e-136.005e-1219.012934GSNgelsolinENSG00000148180105120, 137350
3169-1.2236.701-7.2623.365e-124.915e-1116.863169FOXA1forkhead box A1ENSG00000129514602294
3170.80686.9478.1461.055e-141.966e-1322.52317APAF1apoptotic peptidase activating factor 1ENSG00000120868602233
33030.765712.1810.291.965e-216.938e-2037.823303HSPA1Aheat shock 70kDa protein 1AENSG00000234475, ENSG00000231555, ENSG00000235941, ENSG00000232804, ENSG00000204389, ENSG00000204388, ENSG00000237724, ENSG00000224501, ENSG00000215328, ENSG00000212866140550
3566-0.92766.104-7.2393.891e-125.622e-1116.713566IL4Rinterleukin 4 receptorENSG00000077238147050, 147781, 609423
3602.9465.58918.637.697e-523.648e-49107.3360AQP3aquaporin 3 (Gill blood group)ENSG00000165272600170, 607457
3667-1.257.989-9.0272.279e-175.478e-1628.573667IRS1insulin receptor substrate 1ENSG00000169047125853, 147545
37260.90688.4748.7062.226e-164.919e-1526.333726JUNBjun B proto-oncogeneENSG00000171223165161
3836-0.36979.274-6.3617.581e-108.533e-0911.553836KPNA1karyopherin alpha 1 (importin alpha 5)ENSG00000114030600686
3837-1.09810.44-15.371.237e-392.356e-3779.383837KPNB1karyopherin (importin) beta 1ENSG00000108424602738
3976-2.0647.137-13.161.821e-311.585e-2960.713976LIFleukemia inhibitory factorENSG00000128342159540
40000.64618.9656.9352.541e-113.359e-1014.884000LMNAlamin A/CENSG00000160789115200, 150330, 151660, 159001, 176670, 181350, 212112, 248370, 275210, 277700, 605588, 610140, 613205
4001-2.2447.503-10.282.089e-217.362e-2037.764001LMNB1lamin B1ENSG00000113368150340, 169500
46031.4479.26112.253.426e-282.206e-2653.244603MYBL1v-myb myeloblastosis viral oncogene homolog (avian)-like 1ENSG00000185697159405
4790-0.61217.776-7.4549.959e-131.527e-1118.054790NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1ENSG00000109320164011
4802-1.4757.396-14.357.737e-361.032e-3370.74802NFYCnuclear transcription factor Y, gammaENSG00000066136605344
514741.0479.0636.9512.304e-113.059e-1014.9751474LIMA1LIM domain and actin binding 1ENSG00000050405608364
5154-1.4596.825-8.032.31e-144.173e-1321.755154PDGFAplatelet-derived growth factor alpha polypeptideENSG00000197461173430
52920.6935.9596.4843.731e-104.347e-0912.255292PIM1pim-1 oncogeneENSG00000137193164960
5329-0.78819.122-9.3063.036e-187.893e-1730.565329PLAURplasminogen activator, urokinase receptorENSG00000011422173391
5347-1.4898.164-13.864.891e-345.53e-3266.595347PLK1polo-like kinase 1ENSG00000166851602098
53661.9388.08316.34.39e-431.099e-4087.265366PMAIP1phorbol-12-myristate-13-acetate-induced protein 1ENSG00000141682604959
545411.0537.5567.4977.576e-131.176e-1118.3254541DDIT4DNA-damage-inducible transcript 4ENSG00000168209607729
55300.66549.33410.127.102e-212.375e-1936.555530PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozymeENSG00000138814114105
557400.572410.147.8021.045e-131.785e-1220.2755740ENAHenabled homolog (Drosophila)ENSG00000154380609061
55780.90397.3139.8634.949e-201.508e-1834.635578PRKCAprotein kinase C, alphaENSG00000154229176960
55801.5537.47813.556.706e-336.759e-3163.995580PRKCDprotein kinase C, deltaENSG00000163932176977
55830.72388.5557.3831.569e-122.362e-1117.615583PRKCHprotein kinase C, etaENSG00000027075601367, 605437
5610-0.69048.989-9.7591.078e-193.194e-1833.865610EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 2ENSG00000055332176871
57701.2328.30810.031.431e-204.621e-1935.865770PTPN1protein tyrosine phosphatase, non-receptor type 1ENSG00000196396125853, 176885
5771-1.1038.865-11.374.289e-252.086e-2346.175771PTPN2protein tyrosine phosphatase, non-receptor type 2ENSG00000175354176887
5780.51367.1376.9362.526e-113.344e-1014.88578BAK1BCL2-antagonist/killer 1ENSG00000030110600516
585280.73435.8826.5113.178e-103.736e-0912.458528RRAGDRas-related GTP binding DENSG00000025039608268
5894-0.64069.525-6.9372.521e-113.339e-1014.885894RAF1v-raf-1 murine leukemia viral oncogene homolog 1ENSG00000132155164760, 611553, 611554
59080.347111.257.7811.199e-132.038e-1220.135908RAP1BRAP1B, member of RAS oncogene familyENSG00000127314179530
598-0.91419.808-9.1071.288e-173.191e-1629.14598BCL2L1BCL2-like 1ENSG00000171552600039
6041.818.71312.253.26e-282.105e-2653.29604BCL6B-cell CLL/lymphoma 6ENSG00000113916109565
6249-1.7928.836-21.973.495e-644.098e-61135.56249CLIP1CAP-GLY domain containing linker protein 1ENSG00000130779179838
64411-0.6246.405-6.4364.917e-105.643e-0911.9864411ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3ENSG00000120318606647
66480.94618.17414.212.58e-353.285e-3369.516648SOD2superoxide dismutase 2, mitochondrialENSG00000112096147460, 612634
6654-0.96528.464-9.0731.644e-174.011e-1628.96654SOS1son of sevenless homolog 1 (Drosophila)ENSG00000115904135300, 163955, 182530, 610733
67720.51169.878.0911.535e-142.824e-1322.156772STAT1signal transducer and activator of transcription 1, 91kDaENSG00000115415209950, 600555, 613796, 614162
6880-0.66179.616-7.5077.129e-131.108e-1118.386880TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDaENSG00000085231600822
68850.63957.8898.392.007e-154.08e-1424.166885MAP3K7mitogen-activated protein kinase kinase kinase 7ENSG00000135341602614
70741.1948.0110.436.668e-222.464e-2038.897074TIAM1T-cell lymphoma invasion and metastasis 1ENSG00000156299600687
71500.452211.136.3786.877e-107.769e-0911.657150TOP1topoisomerase (DNA) IENSG00000198900126420
71590.92418.58612.321.915e-281.262e-2653.817159TP53BP2tumor protein p53 binding protein, 2ENSG00000143514602143
7323-0.229910.44-6.4594.301e-104.967e-0912.117323UBE2D3ubiquitin-conjugating enzyme E2D 3ENSG00000109332602963
74140.439412.7412.081.407e-278.564e-2651.847414VCLvinculinENSG00000035403193065, 611407, 613255
7514-0.712111.74-17.567.92e-482.846e-4598.117514XPO1exportin 1 (CRM1 homolog, yeast)ENSG00000082898602559
7528-0.529711.26-10.089.348e-213.085e-1936.287528YY1YY1 transcription factorENSG00000100811600013
7533-0.78268.591-6.4554.406e-105.08e-0912.087533YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptideENSG00000128245113508
7874-0.78529.385-9.1559.107e-182.285e-1629.487874USP7ubiquitin specific peptidase 7 (herpes virus-associated)ENSG00000187555602519
8010.627211.467.1636.238e-128.795e-1116.25801CALM1calmodulin 1 (phosphorylase kinase, delta)ENSG00000143933, ENSG00000160014, ENSG00000198668114180
8061-1.37311.23-12.466.221e-294.29e-2754.938061FOSL1FOS-like antigen 1ENSG00000175592136515
8180.525910.078.0132.59e-144.663e-1321.64818CAMK2Gcalcium/calmodulin-dependent protein kinase II gammaENSG00000148660602123
8295-0.78658.766-9.8286.414e-201.931e-1834.388295TRRAPtransformation/transcription domain-associated proteinENSG00000196367603015
839-0.95657.782-8.6333.716e-168.005e-1525.82839CASP6caspase 6, apoptosis-related cysteine peptidaseENSG00000138794601532
841-0.72738.641-7.7551.428e-132.402e-1219.96841CASP8caspase 8, apoptosis-related cysteine peptidaseENSG00000064012114480, 114550, 211980, 601763, 607271
8420.8628.25311.673.65e-261.978e-2448.61842CASP9caspase 9, apoptosis-related cysteine peptidaseENSG00000132906602234
84271-0.75988.157-8.2355.789e-151.122e-1323.1284271POLDIP3polymerase (DNA-directed), delta interacting protein 3ENSG00000100227611520
8439-0.8948.165-7.7411.563e-132.618e-1219.878439NSMAFneutral sphingomyelinase (N-SMase) activation associated factorENSG00000035681603043
86601.4867.08510.971.027e-234.416e-2243.028660IRS2insulin receptor substrate 2ENSG00000185950125853, 600797
8681.0148.4912.437.578e-295.162e-2754.73868CBLBCbl proto-oncogene, E3 ubiquitin protein ligase BENSG00000114423604491
8772-1.19410.21-13.181.591e-311.39e-2960.858772FADDFas (TNFRSF6)-associated via death domainENSG00000168040602457, 613759
87950.6349.966.3527.956e-108.929e-0911.518795TNFRSF10Btumor necrosis factor receptor superfamily, member 10bENSG00000120889275355, 603612
8837-1.0126.759-11.654.498e-262.415e-2448.48837CFLARCASP8 and FADD-like apoptosis regulatorENSG00000003402603599
890-0.8138.733-9.9991.772e-205.647e-1935.65890CCNA2cyclin A2ENSG00000145386123835
891-0.757310.69-15.012.892e-384.808e-3676.25891CCNB1cyclin B1ENSG00000134057123836
9000.454710.719.3332.507e-186.586e-1730.75900CCNG1cyclin G1ENSG00000113328601578
90430.792110.3910.552.609e-221e-2039.829043SPAG9sperm associated antigen 9ENSG00000008294605430
9266-1.2077.305-14.492.359e-363.305e-3471.889266CYTH2cytohesin 2ENSG00000105443602488
92670.79267.1516.8344.687e-116.018e-1014.289267CYTH1cytohesin 1ENSG00000108669182115
94671.0419.37210.83.843e-231.571e-2141.729467SH3BP5SH3-domain binding protein 5 (BTK-associated)ENSG00000131370605612
9540-0.43448.813-6.3478.178e-109.163e-0911.489540TP53I3tumor protein p53 inducible protein 3ENSG00000115129605171
98820.63777.3326.8564.109e-115.315e-1014.49882TBC1D4TBC1 domain family, member 4ENSG00000136111612465