Test Results

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Gene Set Null TNF receptor signaling pathway

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
1019-0.263210.67-3.8770.00013010.0006885-0.070411019CDK4cyclin-dependent kinase 4ENSG00000135446123829, 609048
103990.48256.8325.0487.812e-075.863e-064.81710399GNB2L1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1ENSG00000204628176981
112212.4246.05911.279.433e-254.471e-2345.3911221DUSP10dual specificity phosphatase 10ENSG00000143507608867
112610.464511.587.469.592e-131.476e-1118.0911261CHPcalcium binding protein P22ENSG00000187446606988
1386-0.51727.487-3.8810.00012830.0006793-0.056831386ATF2activating transcription factor 2ENSG00000115966123811
1387-2.0298.584-17.923.612e-491.437e-46101.21387CREBBPCREB binding proteinENSG00000005339180849, 600140
1390-0.51219.586-8.0072.683e-144.819e-1321.611390CREMcAMP responsive element modulatorENSG00000095794123812
1452-0.178211.48-4.1214.898e-050.00027790.85431452CSNK1A1casein kinase 1, alpha 1ENSG00000113712600505
1457-0.69439.992-12.572.392e-291.718e-2755.881457CSNK2A1casein kinase 2, alpha 1 polypeptideENSG00000101266115440
15400.52695.5456.6191.694e-102.05e-0913.021540CYLDcylindromatosis (turban tumor syndrome)ENSG00000083799132700, 601606, 605018, 605041
16470.620710.155.4669.763e-088.358e-076.8271647GADD45Agrowth arrest and DNA-damage-inducible, alphaENSG00000116717126335
16490.38157.8294.4651.141e-057.207e-052.2421649DDIT3DNA-damage-inducible transcript 3ENSG00000175197126337, 613488
1677-0.81446.046-5.4371.135e-079.617e-076.6821677DFFBDNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)ENSG00000169598601883
18431.5598.3846.0574.202e-094.331e-089.8841843DUSP1dual specificity phosphatase 1ENSG00000120129600714
19590.79334.816.6811.172e-101.443e-0913.381959EGR2early growth response 2ENSG00000122877129010, 145900, 605253, 607678
1977-0.46799.441-4.2412.974e-050.00017511.3291977EIF4Eeukaryotic translation initiation factor 4EENSG00000151247133440
2033-0.78826.866-7.2393.891e-125.622e-1116.712033EP300E1A binding protein p300ENSG00000100393114500, 180849, 602700, 613684
229260.3468.145.0577.457e-075.616e-064.86222926ATF6activating transcription factor 6ENSG00000118217605537
230431.2925.93910.494.085e-221.542e-2039.3823043TNIKTRAF2 and NCK interacting kinaseENSG00000154310610005
230850.59796.3015.6423.92e-083.541e-077.71223085ERC1ELKS/RAB6-interacting/CAST family member 1ENSG00000082805607127
23118-0.48528.522-5.1175.586e-074.287e-065.1423118TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 2ENSG00000055208605101, 612863
23530.4714.8735.5785.479e-084.845e-077.3872353FOSFBJ murine osteosarcoma viral oncogene homologENSG00000170345164810
25341.3348.72513.064.076e-313.466e-2959.912534FYNFYN oncogene related to SRC, FGR, YESENSG00000010810137025
29340.75517.7837.6063.752e-136.005e-1219.012934GSNgelsolinENSG00000148180105120, 137350
31640.53995.7295.3441.815e-071.503e-066.2273164NR4A1nuclear receptor subfamily 4, group A, member 1ENSG00000123358139139
3170.80686.9478.1461.055e-141.966e-1322.52317APAF1apoptotic peptidase activating factor 1ENSG00000120868602233
37260.90688.4748.7062.226e-164.919e-1526.333726JUNBjun B proto-oncogeneENSG00000171223165161
3837-1.09810.44-15.371.237e-392.356e-3779.383837KPNB1karyopherin (importin) beta 1ENSG00000108424602738
40000.64618.9656.9352.541e-113.359e-1014.884000LMNAlamin A/CENSG00000160789115200, 150330, 151660, 159001, 176670, 181350, 212112, 248370, 275210, 277700, 605588, 610140, 613205
4001-2.2447.503-10.282.089e-217.362e-2037.764001LMNB1lamin B1ENSG00000113368150340, 169500
40670.71116.7445.0278.633e-076.43e-064.7214067LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homologENSG00000254087165120
41370.71745.288.1768.615e-151.633e-1322.724137MAPTmicrotubule-associated protein tauENSG00000257437, ENSG00000186868157140, 168600, 172700, 260540, 600274, 601104
42081.3337.60811.521.225e-256.144e-2447.414208MEF2Cmyocyte enhancer factor 2CENSG00000081189600662, 613443
42150.74987.8697.6472.873e-134.639e-1219.274215MAP3K3mitogen-activated protein kinase kinase kinase 3ENSG00000198909602539
4216-0.97977.796-10.011.626e-205.203e-1935.734216MAP3K4mitogen-activated protein kinase kinase kinase 4ENSG00000085511602425
42861.0147.08911.693.194e-261.74e-2448.744286MITFmicrophthalmia-associated transcription factorENSG00000187098103470, 103500, 156845, 193510
46090.335210.924.911.506e-061.083e-054.1854609MYCv-myc myelocytomatosis viral oncogene homolog (avian)ENSG00000136997113970, 190080
46160.7148.3514.1953.613e-050.00020891.1434616GADD45Bgrowth arrest and DNA-damage-inducible, betaENSG00000099860604948
466-1.7918.875-13.623.867e-333.988e-3164.53466ATF1activating transcription factor 1ENSG00000123268123803
4790-0.61217.776-7.4549.959e-131.527e-1118.054790NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1ENSG00000109320164011
4792-0.63910.15-5.1115.75e-074.394e-065.1124792NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alphaENSG00000100906164008, 612132
4926-0.39848.116-3.9838.581e-050.00046670.3234926NUMA1nuclear mitotic apparatus protein 1ENSG00000137497164009
50630.48765.6524.0845.701e-050.00031970.71025063PAK3p21 protein (Cdc42/Rac)-activated kinase 3ENSG00000077264300142, 300558
513471.7578.07216.219.447e-432.287e-4086.551347TAOK3TAO kinase 3ENSG00000135090NA
5154-1.4596.825-8.032.31e-144.173e-1321.755154PDGFAplatelet-derived growth factor alpha polypeptideENSG00000197461173430
52920.6935.9596.4843.731e-104.347e-0912.255292PIM1pim-1 oncogeneENSG00000137193164960
55660.41299.5495.3911.431e-071.198e-066.4575566PRKACAprotein kinase, cAMP-dependent, catalytic, alphaENSG00000072062601639
55780.90397.3139.8634.949e-201.508e-1834.635578PRKCAprotein kinase C, alphaENSG00000154229176960
55801.5537.47813.556.706e-336.759e-3163.995580PRKCDprotein kinase C, deltaENSG00000163932176977
55830.72388.5557.3831.569e-122.362e-1117.615583PRKCHprotein kinase C, etaENSG00000027075601367, 605437
56040.255810.134.4781.075e-056.812e-052.2995604MAP2K1mitogen-activated protein kinase kinase 1ENSG00000169032115150, 176872
56061.6569.05812.582.254e-291.63e-2755.935606MAP2K3mitogen-activated protein kinase kinase 3ENSG00000034152602315
56080.66067.9555.4231.215e-071.027e-066.6165608MAP2K6mitogen-activated protein kinase kinase 6ENSG00000108984601254
5610-0.69048.989-9.7591.078e-193.194e-1833.865610EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 2ENSG00000055332176871
56848-0.51396.517-5.2822.481e-072.01e-065.92556848SPHK2sphingosine kinase 2ENSG00000063176607092
57701.2328.30810.031.431e-204.621e-1935.865770PTPN1protein tyrosine phosphatase, non-receptor type 1ENSG00000196396125853, 176885
5894-0.64069.525-6.9372.521e-113.339e-1014.885894RAF1v-raf-1 murine leukemia viral oncogene homolog 1ENSG00000132155164760, 611553, 611554
58980.47589.2134.15.333e-050.00030070.77365898RALAv-ral simian leukemia viral oncogene homolog A (ras related)ENSG00000006451179550
5901-0.256413.01-5.5496.372e-085.586e-077.2415901RANRAN, member RAS oncogene familyENSG00000132341601179
595-0.780910.02-5.7642.053e-081.921e-078.34595CCND1cyclin D1ENSG00000110092114500, 151400, 168461, 193300, 254500
5960.36634.8634.3242.096e-050.00012671.662596BCL2B-cell CLL/lymphoma 2ENSG00000171791151430
598-0.91419.808-9.1071.288e-173.191e-1629.14598BCL2L1BCL2-like 1ENSG00000171552600039
63040.79527.4134.9791.088e-067.984e-064.4986304SATB1SATB homeobox 1ENSG00000182568602075
637-0.49527.455-4.1364.605e-050.00026240.9128637BIDBH3 interacting domain death agonistENSG00000015475601997
65480.95858.5198.8577.663e-171.776e-1527.386548SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), member 1ENSG00000090020107310
66090.36626.9344.0626.23e-050.00034710.62616609SMPD1sphingomyelin phosphodiesterase 1, acid lysosomalENSG00000166311257200, 607608, 607616
67090.63475.2175.9686.847e-096.858e-089.4086709SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)ENSG00000197694182810, 613477
67720.51169.878.0911.535e-142.824e-1322.156772STAT1signal transducer and activator of transcription 1, 91kDaENSG00000115415209950, 600555, 613796, 614162
6850-0.51235.428-5.0278.623e-076.425e-064.7226850SYKspleen tyrosine kinaseENSG00000165025600085
68850.63957.8898.392.007e-154.08e-1424.166885MAP3K7mitogen-activated protein kinase kinase kinase 7ENSG00000135341602614
6929-0.27119.7-4.2612.736e-050.00016251.4086929TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)ENSG00000071564147141
70910.80336.2595.4689.65e-088.268e-076.8397091TLE4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)ENSG00000106829605132
71500.452211.136.3786.877e-107.769e-0911.657150TOP1topoisomerase (DNA) IENSG00000198900126420
72490.38574.3624.2093.399e-050.00019751.2017249TSC2tuberous sclerosis 2ENSG00000103197191092, 191100, 606690
7323-0.229910.44-6.4594.301e-104.967e-0912.117323UBE2D3ubiquitin-conjugating enzyme E2D 3ENSG00000109332602963
7514-0.712111.74-17.567.92e-482.846e-4598.117514XPO1exportin 1 (CRM1 homolog, yeast)ENSG00000082898602559
75250.285911.074.3961.538e-059.49e-051.9577525YES1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1ENSG00000176105164880
7533-0.78268.591-6.4554.406e-105.08e-0912.087533YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptideENSG00000128245113508
7867-0.273910.28-4.4831.054e-056.693e-052.3187867MAPKAPK3mitogen-activated protein kinase-activated protein kinase 3ENSG00000114738602130
8010.627211.467.1636.238e-128.795e-1116.25801CALM1calmodulin 1 (phosphorylase kinase, delta)ENSG00000143933, ENSG00000160014, ENSG00000198668114180
8021-0.58827.102-6.2551.382e-091.509e-0810.978021NUP214nucleoporin 214kDaENSG00000126883114350, 601626
8050.189213.064.5657.338e-064.775e-052.664805CALM2calmodulin 2 (phosphorylase kinase, delta)ENSG00000143933, ENSG00000160014, ENSG00000198668114182
8061-1.37311.23-12.466.221e-294.29e-2754.938061FOSL1FOS-like antigen 1ENSG00000175592136515
837-0.62167.57-5.2253.285e-072.621e-065.653837CASP4caspase 4, apoptosis-related cysteine peptidaseENSG00000196954602664
839-0.95657.782-8.6333.716e-168.005e-1525.82839CASP6caspase 6, apoptosis-related cysteine peptidaseENSG00000138794601532
840-0.43847.448-5.144.988e-073.872e-065.25840CASP7caspase 7, apoptosis-related cysteine peptidaseENSG00000165806601761
841-0.72738.641-7.7551.428e-132.402e-1219.96841CASP8caspase 8, apoptosis-related cysteine peptidaseENSG00000064012114480, 114550, 211980, 601763, 607271
8420.8628.25311.673.65e-261.978e-2448.61842CASP9caspase 9, apoptosis-related cysteine peptidaseENSG00000132906602234
8439-0.8948.165-7.7411.563e-132.618e-1219.878439NSMAFneutral sphingomyelinase (N-SMase) activation associated factorENSG00000035681603043
84823-0.71568.315-4.4391.273e-057.978e-052.13784823LMNB2lamin B2ENSG00000176619150341, 608709
8550-0.27738.466-4.2133.349e-050.00019481.2168550MAPKAPK5mitogen-activated protein kinase-activated protein kinase 5ENSG00000089022606723
85670.41797.1944.2462.914e-050.0001721.3488567MADDMAP-kinase activating death domainENSG00000110514603584
85690.61348.5398.953.959e-179.402e-1628.038569MKNK1MAP kinase interacting serine/threonine kinase 1ENSG00000079277606724
8681.0148.4912.437.578e-295.162e-2754.73868CBLBCbl proto-oncogene, E3 ubiquitin protein ligase BENSG00000114423604491
8772-1.19410.21-13.181.591e-311.39e-2960.858772FADDFas (TNFRSF6)-associated via death domainENSG00000168040602457, 613759
88780.61875.8246.7846.355e-118.021e-1013.988878SQSTM1sequestosome 1ENSG00000161011601530, 602080
90200.7366.4964.8881.674e-061.196e-054.0829020MAP3K14mitogen-activated protein kinase kinase kinase 14ENSG00000006062604655
9064-0.64235.886-7.2593.427e-124.999e-1116.849064MAP3K6mitogen-activated protein kinase kinase kinase 6ENSG00000142733604468
92610.57979.7677.273.206e-124.701e-1116.99261MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2ENSG00000162889602006
9448-0.40710.18-5.0447.961e-075.963e-064.7999448MAP4K4mitogen-activated protein kinase kinase kinase kinase 4ENSG00000071054604666