Test Results

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Gene Set Broad REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
112141.2777.76714.173.753e-354.697e-3369.1311214AKAP13A kinase (PRKA) anchor protein 13ENSG00000170776604686
113-0.53346.129-4.2293.127e-050.00018321.281113ADCY7adenylate cyclase 7ENSG00000121281600385
12410.36824.7284.4231.365e-058.503e-052.0711241LTB4Rleukotriene B4 receptorENSG00000213903601531
136-1.0759.899-6.8923.309e-114.323e-1014.62136ADORA2Badenosine A2b receptorENSG00000170425600446
1541.5058.75911.791.467e-268.253e-2549.51154ADRB2adrenergic, beta-2-, receptor, surfaceENSG00000169252109690, 600807, 601665
1850.62494.535.9816.361e-096.392e-089.48185AGTR1angiotensin II receptor, type 1ENSG00000144891106165, 145500, 267430
1894-0.416810.08-6.1222.929e-093.097e-0810.241894ECT2epithelial cell transforming sequence 2 oncogeneENSG00000114346600586
1902-2.1259.725-30.162.288e-921.02e-88199.71902LPAR1lysophosphatidic acid receptor 1ENSG00000198121602282
233650.58196.2484.9091.516e-061.09e-054.17823365ARHGEF12Rho guanine nucleotide exchange factor (GEF) 12ENSG00000196914601626, 604763
233700.450110.894.3252.084e-050.00012611.66723370ARHGEF18Rho/Rac guanine nucleotide exchange factor (GEF) 18ENSG00000104880NA
235330.28464.4914.0476.615e-050.0003670.569223533PIK3R5phosphoinositide-3-kinase, regulatory subunit 5ENSG00000141506611317
235960.93469.76411.21.581e-247.354e-2344.8823596OPN3opsin 3ENSG00000054277606695
27670.3978.676.5332.792e-103.296e-0912.532767GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)ENSG00000088256139313
27701.5697.5917.289.007e-473.04e-4495.692770GNAI1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1ENSG00000127955139310
27730.150311.214.1274.789e-050.00027220.87552773GNAI3guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3ENSG00000065135139370
2852-0.64835.76-6.4684.075e-104.718e-0912.162852GPERG protein-coupled estrogen receptor 1ENSG00000164850601805
28691.3016.00312.166.778e-284.229e-2652.562869GRK5G protein-coupled receptor kinase 5ENSG00000198873600870
3010.578810.566.1312.786e-092.952e-0810.28301ANXA1annexin A1ENSG00000135046151690
37080.99727.9967.3751.649e-122.475e-1117.563708ITPR1inositol 1, 4, 5-trisphosphate receptor, type 1ENSG00000150995147265, 606658
3881.7877.22711.316.71e-253.215e-2345.72388RHOBras homolog family member BENSG00000143878165370
4157-0.29594.47-4.0297.11e-050.00039230.5014157MC1Rmelanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)ENSG00000258839155555, 155600, 203200, 226300, 266300, 613098, 613099
5029-0.87796.876-6.2211.675e-091.812e-0810.785029P2RY2purinergic receptor P2Y, G-protein coupled, 2ENSG00000175591600041
506501.1497.93510.961.051e-234.51e-224350650ARHGEF3Rho guanine nucleotide exchange factor (GEF) 3ENSG00000163947612115
508650.81029.6889.4021.512e-184.044e-1731.2550865HEBP1heme binding protein 1ENSG00000013583605826
51430.26794.1284.5976.352e-064.171e-052.8025143PDE4Cphosphodiesterase 4C, cAMP-specificENSG00000105650600128
5151-0.38399.572-3.8340.00015420.000807-0.23075151PDE8Aphosphodiesterase 8AENSG00000073417602972
51700.72298.9794.8631.876e-061.332e-053.9735170PDPK13-phosphoinositide dependent protein kinase-1ENSG00000140992605213
5540.34924.4194.9771.094e-068.028e-064.492554AVPR2arginine vasopressin receptor 2ENSG00000126895300538, 300539, 304800
57240.37265.4253.8460.00014690.0007706-0.18485724PTAFRplatelet-activating factor receptorENSG00000169403173393
57320.86025.9887.7271.707e-132.848e-1219.795732PTGER2prostaglandin E receptor 2 (subtype EP2), 53kDaENSG00000125384176804, 208550
57341.7238.30410.321.597e-215.721e-2038.035734PTGER4prostaglandin E receptor 4 (subtype EP4)ENSG00000171522601586
5744-0.67196.919-4.2572.778e-050.00016491.3935744PTHLHparathyroid hormone-like hormoneENSG00000087494168470, 613382
58800.251310.154.6924.134e-062.793e-053.2145880RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)ENSG00000128340602049, 608203
63640.99734.6654.6225.666e-063.752e-052.9126364CCL20chemokine (C-C motif) ligand 20ENSG00000115009601960
64530.46267.9444.9291.38e-069.984e-064.2696453ITSN1intersectin 1 (SH3 domain protein)ENSG00000205726602442
6654-0.96528.464-9.0731.644e-174.011e-1628.96654SOS1son of sevenless homolog 1 (Drosophila)ENSG00000115904135300, 163955, 182530, 610733
69150.66376.4495.7761.934e-081.813e-078.3986915TBXA2Rthromboxane A2 receptorENSG00000006638188070, 614009
70741.1948.0110.436.668e-222.464e-2038.897074TIAM1T-cell lymphoma invasion and metastasis 1ENSG00000156299600687
7204-0.52477.799-4.7533.126e-062.151e-053.4827204TRIOtriple functional domain (PTPRF interacting)ENSG00000038382601893
78521.1145.7376.6711.243e-101.526e-0913.327852CXCR4chemokine (C-X-C motif) receptor 4ENSG00000121966162643, 193670
8460.2754.6894.2772.562e-050.00015271.47846CASRcalcium-sensing receptorENSG00000036828145980, 146200, 239200, 601199, 612899
9170-1.0366.323-8.8925.996e-171.403e-1527.629170LPAR2lysophosphatidic acid receptor 2ENSG00000064547605110
9826-0.3796.876-3.9948.208e-050.00044840.3659826ARHGEF11Rho guanine nucleotide exchange factor (GEF) 11ENSG00000132694605708