Test Results

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Gene Set Null ErbB1 downstream signaling

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10006-0.99787.799-5.2932.339e-076.587e-066.56310006ABI1abl-interactor 1ENSG00000136754603050
1027-1.3057.936-6.0065.562e-092.706e-0710.141027CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)ENSG00000111276600778, 610755
10468-1.3179.442-6.7985.813e-115.833e-0914.5210468FSTfollistatinENSG00000134363136470, 184700
1111-1.0238.88-5.1444.904e-071.244e-055.8581111CHEK1checkpoint kinase 1ENSG00000149554603078
11240.62254.5085.5416.648e-082.244e-067.7631124CHN2chimerin (chimaerin) 2ENSG00000106069602857
112611.1416.314.5956.395e-060.00010543.42311261CHPcalcium binding protein P22ENSG00000187446606988
11290.62634.4195.067.367e-071.752e-055.4711129CHRM2cholinergic receptor, muscarinic 2ENSG00000181072118493
12770.7595.924.3641.768e-050.00024682.4651277COL1A1collagen, type I, alpha 1ENSG00000108821114000, 120150, 130000, 130060, 166200, 166210, 166220, 166710, 259420
1387-1.4948.584-8.382.144e-158.844e-1324.391387CREBBPCREB binding proteinENSG00000005339180849, 600140
1390-0.90529.586-8.9912.959e-172.273e-1428.541390CREMcAMP responsive element modulatorENSG00000095794123812
1453-0.51569.618-6.3737.071e-104.731e-0812.121453CSNK1Dcasein kinase 1, deltaENSG00000141551600864
1454-1.0877.495-65.736e-092.772e-0710.111454CSNK1Ecasein kinase 1, epsilonENSG00000213923600863
1457-0.60239.992-6.9282.651e-112.938e-0915.281457CSNK2A1casein kinase 2, alpha 1 polypeptideENSG00000101266115440
14950.57424.2375.7731.957e-087.813e-078.9321495CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDaENSG00000044115116805
1871-1.1718.431-6.621.679e-101.394e-0813.51871E2F3E2F transcription factor 3ENSG00000112242600427
1977-1.118.898-4.8951.613e-063.339e-054.7271977EIF4Eeukaryotic translation initiation factor 4EENSG00000151247133440
2017-1.1248.19-5.0816.638e-071.602e-055.572017CTTNcortactinENSG00000085733164765
2060-0.69898.016-4.8412.078e-064.145e-054.4872060EPS15epidermal growth factor receptor pathway substrate 15ENSG00000085832600051
21151.2415.1155.0288.591e-071.987e-055.3252115ETV1ets variant 1ENSG00000006468600541
23118-1.1288.522-7.565.069e-139.734e-1119.123118TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 2ENSG00000055208605101, 612863
23411-0.99179.158-6.3976.142e-104.223e-0812.2523411SIRT1sirtuin 1ENSG00000096717604479
25341.2576.2685.7012.874e-081.092e-068.5652534FYNFYN oncogene related to SRC, FGR, YESENSG00000010810137025
25898-1.358.87-7.1337.532e-129.869e-1016.4925898RCHY1ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligaseENSG00000163743607680
25998-0.76978.871-5.0726.944e-071.671e-055.52725998IBTKinhibitor of Bruton agammaglobulinemia tyrosine kinaseENSG00000005700606457
27252-1.1438.6-4.4081.463e-050.00021042.64327252KLHL20kelch-like 20 (Drosophila)ENSG00000076321NA
2767-0.84568.965-5.9069.607e-094.272e-079.6142767GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)ENSG00000088256139313
30820.56474.8155.0039.667e-072.177e-055.2133082HGFhepatocyte growth factor (hepapoietin A; scatter factor)ENSG00000019991142409, 608265
31591.8626.1534.891.656e-063.4e-054.7023159HMGA1high mobility group AT-hook 1ENSG00000137309125853, 600701
3170.66845.3314.7293.493e-066.373e-053.995317APAF1apoptotic peptidase activating factor 1ENSG00000120868602233
35590.5414.3656.0414.585e-092.295e-0710.323559IL2RAinterleukin 2 receptor, alphaENSG00000134460147730, 601942, 606367
3597-0.66588.827-6.162.368e-091.316e-0710.963597IL13RA1interleukin 13 receptor, alpha 1ENSG00000131724300119
36351.0954.3467.5037.292e-131.341e-1018.753635INPP5Dinositol polyphosphate-5-phosphatase, 145kDaENSG00000168918601582
3685-1.2519.391-6.3249.358e-106.043e-0811.853685ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)ENSG00000138448193210
36900.71414.6075.5127.724e-082.527e-067.623690ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)ENSG00000259753, ENSG00000259207173470, 273800, 608446
37180.58654.4315.0976.141e-071.497e-055.6443718JAK3Janus kinase 3ENSG00000105639600173
3725-1.3528.139-5.5227.316e-082.422e-067.6713725JUNjun proto-oncogeneENSG00000177606165160
3836-0.76738.839-5.5476.438e-082.186e-067.7933836KPNA1karyopherin alpha 1 (importin alpha 5)ENSG00000114030600686
4026-0.66899.174-4.9281.382e-062.957e-054.8744026LPPLIM domain containing preferred translocation partner in lipomaENSG00000145012600700, 601626
4170-0.63899.491-6.3597.639e-105.035e-0812.044170MCL1myeloid cell leukemia sequence 1 (BCL2-related)ENSG00000143384159552
4216-1.5438.806-7.838.694e-142.279e-1120.814216MAP3K4mitogen-activated protein kinase kinase kinase 4ENSG00000085511602425
42480.52454.7044.5328.465e-060.00013353.1594248MGAT3mannosyl (beta-1, 4-)-glycoprotein beta-1, 4-N-acetylglucosaminyltransferaseENSG00000128268604621
43231.1315.7664.8811.73e-063.536e-054.664323MMP14matrix metallopeptidase 14 (membrane-inserted)ENSG00000157227600754
466-1.538.875-7.391.498e-122.49e-1018.05466ATF1activating transcription factor 1ENSG00000123268123803
4690-1.1128.81-6.0843.611e-091.884e-0710.554690NCK1NCK adaptor protein 1ENSG00000158092600508
4801-0.77057.769-5.712.747e-081.048e-068.6084801NFYBnuclear transcription factor Y, betaENSG00000120837189904
4802-1.077.396-6.6161.72e-101.419e-0813.484802NFYCnuclear transcription factor Y, gammaENSG00000066136605344
5054-1.5068.572-5.1494.774e-071.222e-055.8835054SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1ENSG00000106366173360, 613329
51499-0.554710.9-4.3981.524e-050.00021842.60551499TRIAP1TP53 regulated inhibitor of apoptosis 1ENSG00000170855NA
5170-1.1238.979-4.7982.543e-064.876e-054.2955170PDPK13-phosphoinositide dependent protein kinase-1ENSG00000140992605213
52680.87039.854.3841.617e-050.00022972.5495268SERPINB5serpin peptidase inhibitor, clade B (ovalbumin), member 5ENSG00000206075154790
545-1.1098.796-6.0913.466e-091.821e-0710.59545ATRataxia telangiectasia and Rad3 relatedENSG00000175054210600, 601215
54520.71724.4525.9736.654e-093.141e-079.9665452POU2F2POU class 2 homeobox 2ENSG00000028277164176
5532-0.98729.827-7.8776.364e-141.75e-1121.115532PPP3CBprotein phosphatase 3, catalytic subunit, beta isozymeENSG00000107758114106
55660.8184.5475.3831.491e-074.466e-066.9925566PRKACAprotein kinase, cAMP-dependent, catalytic, alphaENSG00000072062601639
55763-0.34079.734-4.5677.261e-060.00011723.30355763EXOC1exocyst complex component 1ENSG00000090989607879
55800.94447.4785.2343.139e-078.507e-066.2825580PRKCDprotein kinase C, deltaENSG00000163932176977
55831.0066.6624.5159.162e-060.00014273.0845583PRKCHprotein kinase C, etaENSG00000027075601367, 605437
5591-0.63729.881-5.272.63e-077.27e-066.4515591PRKDCprotein kinase, DNA-activated, catalytic polypeptideENSG00000253729600899
55990.75884.765.5197.433e-082.449e-067.6565599MAPK8mitogen-activated protein kinase 8ENSG00000107643601158
56020.69354.5245.292.38e-076.678e-066.5465602MAPK10mitogen-activated protein kinase 10ENSG00000109339602897, 606369
57103-1.3548.443-6.4684.08e-102.987e-0812.6557103C12orf5chromosome 12 open reading frame 5ENSG00000078237610775
5771-1.1648.865-7.6193.459e-137.264e-1119.475771PTPN2protein tyrosine phosphatase, non-receptor type 2ENSG00000175354176887
58292.0915.6624.4671.128e-050.00016982.8885829PXNpaxillinENSG00000089159602505
5867-0.53249.21-4.7123.779e-066.789e-053.9215867RAB4ARAB4A, member RAS oncogene familyENSG00000168118179511
58991.0937.7384.5866.672e-060.00010893.3835899RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)ENSG00000144118179551
5960.38664.1594.5587.571e-060.00012143.264596BCL2B-cell CLL/lymphoma 2ENSG00000171791151430
6198-1.3358.553-6.1622.331e-091.302e-0710.976198RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1ENSG00000108443608938
6249-1.0218.836-7.9543.833e-141.154e-1121.66249CLIP1CAP-GLY domain containing linker protein 1ENSG00000130779179838
64530.8937.9446.0434.518e-092.267e-0710.346453ITSN1intersectin 1 (SH3 domain protein)ENSG00000205726602442
64750-0.679811.12-5.3232.02e-075.831e-066.70264750SMURF2SMAD specific E3 ubiquitin protein ligase 2ENSG00000108854605532
6591-1.0489.291-4.9571.208e-062.635e-055.0016591SNAI2snail homolog 2 (Drosophila)ENSG00000019549172800, 602150, 608890
664-0.715411.29-4.4671.129e-050.00016982.888664BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3ENSG00000176171603293
6654-0.99448.464-5.9388.056e-093.662e-079.7836654SOS1son of sevenless homolog 1 (Drosophila)ENSG00000115904135300, 163955, 182530, 610733
67770.54044.5834.4969.929e-060.00015263.0086777STAT5Bsignal transducer and activator of transcription 5BENSG00000173757245590, 604260
67780.61214.5566.6431.465e-101.241e-0813.636778STAT6signal transducer and activator of transcription 6, interleukin-4 inducedENSG00000166888601512
6880-0.78689.616-5.6713.371e-081.26e-068.4126880TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDaENSG00000085231600822
6929-0.76658.259-4.6495.015e-068.618e-053.6536929TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)ENSG00000071564147141
70330.87544.8655.2772.535e-077.068e-066.4867033TFF3trefoil factor 3 (intestinal)ENSG00000160180600633
70390.79134.835.5167.539e-082.477e-067.6437039TGFAtransforming growth factor, alphaENSG00000163235190170
7082-0.682810.37-5.8541.271e-085.413e-079.3467082TJP1tight junction protein 1 (zona occludens 1)ENSG00000104067601009
7321-0.80169.799-5.6683.415e-081.274e-068.47321UBE2D1ubiquitin-conjugating enzyme E2D 1ENSG00000072401602961
7322-0.77377.124-4.6415.217e-068.9e-053.6167322UBE2D2ubiquitin-conjugating enzyme E2D 2ENSG00000131508602962
7323-0.309810.44-5.537.025e-082.339e-067.717323UBE2D3ubiquitin-conjugating enzyme E2D 3ENSG00000109332602963
7528-0.39811.26-4.8132.369e-064.621e-054.3627528YY1YY1 transcription factorENSG00000100811600013
77860.71875.9565.6962.946e-081.116e-068.5417786MAP3K12mitogen-activated protein kinase kinase kinase 12ENSG00000139625600447
78320.68564.9285.077.019e-071.687e-055.5177832BTG2BTG family, member 2ENSG00000159388601597
7874-0.82999.385-6.1472.54e-091.401e-0710.897874USP7ubiquitin specific peptidase 7 (herpes virus-associated)ENSG00000187555602519
8160.90025.4985.938.399e-093.795e-079.743816CAMK2Bcalcium/calmodulin-dependent protein kinase II betaENSG00000058404607707
8295-0.61888.766-4.9121.492e-063.126e-054.8018295TRRAPtransformation/transcription domain-associated proteinENSG00000196367603015
83941.1625.2434.3851.609e-050.00022882.5548394PIP5K1Aphosphatidylinositol-4-phosphate 5-kinase, type I, alphaENSG00000143398603275
8493-0.92328.269-4.6594.799e-068.313e-053.6958493PPM1Dprotein phosphatase, Mg2+/Mn2+ dependent, 1DENSG00000170836114480, 605100
8795-0.6899.96-4.3861.608e-050.00022882.5548795TNFRSF10Btumor necrosis factor receptor superfamily, member 10bENSG00000120889275355, 603612
8853-0.62639.495-6.1322.768e-091.508e-0710.818853ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2ENSG00000151693603817
89860.64817.0534.5667.281e-060.00011733.3018986RPS6KA4ribosomal protein S6 kinase, 90kDa, polypeptide 4ENSG00000162302603606
90210.88514.695.8381.387e-085.852e-079.2629021SOCS3suppressor of cytokine signaling 3ENSG00000184557604176, 605805
9200.53974.574.9979.945e-072.224e-055.186920CD4CD4 moleculeENSG00000010610186940, 613949
9266-0.89587.305-6.8314.786e-114.982e-0914.719266CYTH2cytohesin 2ENSG00000105443602488
9330.95595.7965.057.712e-071.823e-055.427933CD22CD22 moleculeENSG00000012124107266
9448-0.776110.18-6.113.12e-091.667e-0710.699448MAP4K4mitogen-activated protein kinase kinase kinase kinase 4ENSG00000071054604666
9475-0.54229.46-5.3232.021e-075.831e-066.7029475ROCK2Rho-associated, coiled-coil containing protein kinase 2ENSG00000134318604002