Test Results

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Gene Set Null Signaling by GPCR

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
106360.48575.1013.9370.00010280.0010490.817310636RGS14regulator of G-protein signaling 14ENSG00000169220602513
1120.84036.1593.8660.0001360.0013230.5566112ADCY6adenylate cyclase 6ENSG00000174233600294
11290.62634.4195.067.367e-071.752e-055.4711129CHRM2cholinergic receptor, muscarinic 2ENSG00000181072118493
115-0.97167.863-4.7083.842e-066.879e-053.905115ADCY9adenylate cyclase 9ENSG00000162104603302
12330.50264.3984.3312.036e-050.00027732.3331233CCR4chemokine (C-C motif) receptor 4ENSG00000183813604836
12680.29344.2223.0530.0024710.01446-2.1061268CNR1cannabinoid receptor 1 (brain)ENSG00000118432114610
12690.41084.7753.7640.00020170.0018450.19061269CNR2cannabinoid receptor 2 (macrophage)ENSG00000188822605051
133-1.3839.03-3.9718.991e-050.00094440.9421133ADMadrenomedullinENSG00000148926103275
1560.69445.8084.1694.019e-050.00048951.695156ADRBK1adrenergic, beta, receptor kinase 1ENSG00000173020109635
18130.63014.8025.5048.02e-082.612e-067.5841813DRD2dopamine receptor D2ENSG00000149295126450, 159900
1870.45774.4194.1424.5e-050.0005371.589187APLNRapelin receptorENSG00000134817600052
1902-0.58367.883-3.7950.00017930.001670.30011902LPAR1lysophosphatidic acid receptor 1ENSG00000198121602282
21502.1277.683.8450.00014740.0014170.48182150F2RL1coagulation factor II (thrombin) receptor-like 1ENSG00000164251600933
232360.56924.7944.8332.156e-064.277e-054.45223236PLCB1phospholipase C, beta 1 (phosphoinositide-specific)ENSG00000182621607120, 613722
235330.3954.4913.5690.00041840.00336-0.48423533PIK3R5phosphoinositide-3-kinase, regulatory subunit 5ENSG00000141506611317
25500.71725.5033.1840.0016080.01013-1.7172550GABBR1gamma-aminobutyric acid (GABA) B receptor, 1ENSG00000232569, ENSG00000206466, ENSG00000237051, ENSG00000206511, ENSG00000237112, ENSG00000204681, ENSG00000232632603540
264760.39934.7533.060.0024120.01421-2.08426476OR10J1olfactory receptor, family 10, subfamily J, member 1ENSG00000196184NA
265320.42494.0314.2293.124e-050.00039591.93126532OR10H3olfactory receptor, family 10, subfamily H, member 3ENSG00000171936NA
266580.44834.2854.2812.514e-050.00033082.13426658OR7C2olfactory receptor, family 7, subfamily C, member 2ENSG00000127529NA
266590.51874.6674.3941.548e-050.00022142.5926659OR7A5olfactory receptor, family 7, subfamily A, member 5ENSG00000188269NA
27400.63125.0664.7243.581e-066.501e-053.9712740GLP1Rglucagon-like peptide 1 receptorENSG00000112164138032
2767-0.84568.965-5.9069.607e-094.272e-079.6142767GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)ENSG00000088256139313
2773-0.4357.251-3.4580.00062310.004664-0.85052773GNAI3guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3ENSG00000065135139370
28690.5345.1884.233.123e-050.00039591.9312869GRK5G protein-coupled receptor kinase 5ENSG00000198873600870
29160.4624.114.0257.252e-050.000791.1432916GRM6glutamate receptor, metabotropic 6ENSG00000113262257270, 604096
30600.22794.0453.4470.00064910.004815-0.88793060HCRThypocretin (orexin) neuropeptide precursorENSG00000161610161400, 602358
32690.58245.9253.8820.00012790.0012610.61363269HRH1histamine receptor H1ENSG00000196639600167
32740.42834.6054.557.848e-060.00012493.233274HRH2histamine receptor H2ENSG00000113749142703
33620.65444.9875.4191.24e-073.822e-067.1673362HTR65-hydroxytryptamine (serotonin) receptor 6, G protein-coupledENSG00000158748601109
35770.35264.3633.6130.00035520.002951-0.33273577CXCR1chemokine (C-X-C motif) receptor 1ENSG00000163464146929, 609423
36270.59834.3145.9776.518e-093.096e-079.9863627CXCL10chemokine (C-X-C motif) ligand 10ENSG00000169245147310
48861.4345.0473.0530.0024720.01446-2.1064886NPY1Rneuropeptide Y receptor Y1ENSG00000164128162641
49231.3585.0276.2181.706e-091.019e-0711.274923NTSR1neurotensin receptor 1 (high affinity)ENSG00000101188162651
49920.60844.7685.3391.86e-075.431e-066.7814992OR1F1olfactory receptor, family 1, subfamily F, member 1ENSG00000168124603232
50300.47174.2994.567.475e-060.00012013.2765030P2RY4pyrimidinergic receptor P2Y, G-protein coupled, 4ENSG00000186912300038
51083-1.4048.197-4.32.324e-050.00030892.20851083GALgalanin prepropeptideENSG00000069482137035
51390.59264.2935.527.419e-082.449e-067.6585139PDE3Aphosphodiesterase 3A, cGMP-inhibitedENSG00000172572123805
51400.42074.7963.9529.695e-050.0010020.87185140PDE3Bphosphodiesterase 3B, cGMP-inhibitedENSG00000152270602047
51430.5854.4715.1883.943e-071.036e-056.0655143PDE4Cphosphodiesterase 4C, cAMP-specificENSG00000105650600128
5151-0.77519.572-4.9171.455e-063.061e-054.8245151PDE8Aphosphodiesterase 8AENSG00000073417602972
51530.26064.5243.0470.0025180.01469-2.1235153PDE1Bphosphodiesterase 1B, calmodulin-dependentENSG00000123360171891
5170-1.1238.979-4.7982.543e-064.876e-054.2955170PDPK13-phosphoinositide dependent protein kinase-1ENSG00000140992605213
52960.445.2273.2490.0012890.008451-1.5165296PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)ENSG00000105647603157
5332-1.0358.166-4.9251.407e-062.993e-054.8575332PLCB4phospholipase C, beta 4ENSG00000101333600810
53640.60985.1653.8460.0001470.0014140.48475364PLXNB1plexin B1ENSG00000164050601053
55800.94447.4785.2343.139e-078.507e-066.2825580PRKCDprotein kinase C, deltaENSG00000163932176977
55831.0066.6624.5159.162e-060.00014273.0845583PRKCHprotein kinase C, etaENSG00000027075601367, 605437
55880.41764.7553.3450.000930.006462-1.2185588PRKCQprotein kinase C, thetaENSG00000065675600448
566560.56654.1985.361.677e-074.935e-066.8856656OR2S2olfactory receptor, family 2, subfamily S, member 2ENSG00000122718NA
57240.625.4254.0656.151e-050.00069171.2975724PTAFRplatelet-activating factor receptorENSG00000169403173393
57310.61434.7624.3811.64e-050.00023132.5365731PTGER1prostaglandin E receptor 1 (subtype EP1), 42kDaENSG00000160951176802
5734-0.89288.304-3.3960.00077620.00556-1.0525734PTGER4prostaglandin E receptor 4 (subtype EP4)ENSG00000171522601586
57390.3964.683.4320.00068370.005028-0.93565739PTGIRprostaglandin I2 (prostacyclin) receptor (IP)ENSG00000160013600022
57450.34914.1964.2363.035e-050.00038791.9585745PTH1Rparathyroid hormone 1 receptorENSG00000160801125350, 156400, 166000, 168468, 215045, 600002
59990.78584.9844.9241.408e-062.994e-054.8555999RGS4regulator of G-protein signaling 4ENSG00000117152602516, 604906
60100.49224.1414.9381.319e-062.841e-054.9186010RHOrhodopsinENSG00000163914136880, 180380, 610445, 613731
63510.56814.3265.4531.045e-073.311e-067.3316351CCL4chemokine (C-C motif) ligand 4ENSG00000129277182284
63670.52374.8724.4571.182e-050.00017642.8446367CCL22chemokine (C-C motif) ligand 22ENSG00000102962602957
63700.37544.0364.0566.389e-050.00071451.2616370CCL25chemokine (C-C motif) ligand 25ENSG00000131142602565
66080.596753.810.00016920.0015880.35366608SMOsmoothened, frizzled family receptorENSG00000128602601500
67520.42164.2024.4141.423e-050.00020572.676752SSTR2somatostatin receptor 2ENSG00000180616182452
67530.32144.5523.2560.0012590.008309-1.4946753SSTR3somatostatin receptor 3ENSG00000183473182453
68660.35224.9323.1250.0019540.01192-1.8946866TAC3tachykinin 3ENSG00000166863146110, 162330
69150.36884.9753.5460.00045420.003598-0.55956915TBXA2Rthromboxane A2 receptorENSG00000006638188070, 614009
83251.3957.0623.150.0017970.01112-1.8188325FZD8frizzled family receptor 8ENSG00000177283606146
8460.52914.6895.2283.241e-078.731e-066.252846CASRcalcium-sensing receptorENSG00000036828145980, 146200, 239200, 601199, 612899
84840.44624.8133.3980.00077090.005531-1.0468484GALR3galanin receptor 3ENSG00000128310603692
85030.40354.6053.2620.0012330.008155-1.4758503PIK3R3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)ENSG00000117461606076
9475-0.54229.46-5.3232.021e-075.831e-066.7029475ROCK2Rho-associated, coiled-coil containing protein kinase 2ENSG00000134318604002
96280.84154.2798.2256.202e-152.159e-1223.369628RGS6regulator of G-protein signaling 6ENSG00000182732603894