Test Results

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Gene Set Broad MOOTHA_MITOCHONDRIA

featureNameslogFCAveExprtP.Valueadj.P.ValBENTREZIDSYMBOLGENENAMEENSEMBL.HsaOMIM
10061-0.33964.763-2.3950.017240.7422-3.1210061ABCF2ATP-binding cassette, sub-family F (GCN20), member 2ENSG00000033050612510
100630.251311.321.7450.082030.819-4.20110063COX17COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)ENSG00000138495604813
10166-0.477.476-2.6340.0088820.6901-2.64110166SLC25A15solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15ENSG00000102743238970, 603861
104490.27467.7851.7090.088440.8193-4.25110449ACAA2acetyl-CoA acyltransferase 2ENSG00000167315604770
10469-0.35468.726-1.8620.06360.8143-4.03110469TIMM44translocase of inner mitochondrial membrane 44 homolog (yeast)ENSG00000104980605058
10578-0.18093.974-1.940.053340.8143-3.91210578GNLYgranulysinENSG00000115523188855
106710.26859.7421.6150.10730.8236-4.37710671DCTN6dynactin 6ENSG00000104671612963
10730-0.27319.881-1.8910.05960.8143-3.98710730YME1L1YME1-like 1 (S. cerevisiae)ENSG00000136758607472
109350.33114.3821.9390.053490.8143-3.91310935PRDX3peroxiredoxin 3ENSG00000165672604769
10939-0.36858.692-2.7150.0070070.6671-2.46810939AFG3L2AFG3 ATPase family gene 3-like 2 (S. cerevisiae)ENSG00000141385604581, 610246
11600.17174.2731.6790.09420.8193-4.2921160CKMT2creatine kinase, mitochondrial 2 (sarcomeric)ENSG00000131730123295
12010.35496.5891.70.090170.8193-4.2641201CLN3ceroid-lipofuscinosis, neuronal 3ENSG00000261832, ENSG00000188603204200, 607042
13400.332411.791.7760.076720.819-4.1571340COX6B1cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)ENSG00000126267124089, 220110
1353-0.42375.012-1.7450.082060.819-4.2011353COX11COX11 cytochrome c oxidase assembly homolog (yeast)ENSG00000166260603648
1373-0.44486.788-1.8480.065530.8143-4.0511373CPS1carbamoyl-phosphate synthase 1, mitochondrialENSG00000021826237300, 265380, 608307
13740.36249.9471.8780.061380.8143-4.0071374CPT1Acarnitine palmitoyltransferase 1A (liver)ENSG00000110090255120, 600528
15280.447810.023.1530.0017840.4159-1.4541528CYB5Acytochrome b5 type A (microsomal)ENSG00000166347250790, 613218
15930.3435.7011.7690.077960.819-4.1671593CYP27A1cytochrome P450, family 27, subfamily A, polypeptide 1ENSG00000135929213700, 606530
15940.79445.3482.9450.0034840.5235-1.9531594CYP27B1cytochrome P450, family 27, subfamily B, polypeptide 1ENSG00000111012264700, 609506
16290.68596.1561.6050.10950.8236-4.391629DBTdihydrolipoamide branched chain transacylase E2ENSG00000137992248600, 248610
1632-0.30798.298-1.6090.10870.8236-4.3851632ECI1enoyl-CoA delta isomerase 1ENSG00000167969600305
17160.38167.8182.0590.040370.7924-3.721716DGUOKdeoxyguanosine kinaseENSG00000114956251880, 601465
17370.37199.2491.720.086550.8193-4.2371737DLATdihydrolipoamide S-acetyltransferaseENSG00000150768245348, 608770
17570.25684.6011.7450.082050.819-4.2011757SARDHsarcosine dehydrogenaseENSG00000123453268900, 604455
17770.77747.1262.320.021040.7571-3.2621777DNASE2deoxyribonuclease II, lysosomalENSG00000105612126350
18-0.26054.881-1.6190.10640.8236-4.37218ABAT4-aminobutyrate aminotransferaseENSG00000183044137150, 613163
1890-0.4194.382-2.3320.020370.7511-3.2391890TYMPthymidine phosphorylaseENSG00000025708131222, 603041
2040.54879.7271.7530.080620.819-4.19204AK2adenylate kinase 2ENSG00000004455103020, 267500
21100.33676.6651.7320.084230.8193-4.2192110ETFDHelectron-transferring-flavoprotein dehydrogenaseENSG00000171503231675, 231680
2271-0.44095.802-1.8920.059450.8143-3.9852271FHfumarate hydrataseENSG00000091483136850, 150800, 605839, 606812
23107-0.2549.076-2.0190.044370.7977-3.78523107MRPS27mitochondrial ribosomal protein S27ENSG00000113048611989
234090.2914.2422.1160.035140.7916-3.62423409SIRT4sirtuin 4ENSG00000089163604482
235300.4636.41.6440.10120.823-4.33923530NNTnicotinamide nucleotide transhydrogenaseENSG00000112992607878
23609-0.17599.657-2.1550.031960.7773-3.55723609MKRN2makorin ring finger protein 2ENSG00000075975608426
2395-0.39647.974-1.7310.084470.8193-4.2212395FXNfrataxinENSG00000165060229300, 606829
258280.40648.0961.6070.1090.8236-4.38825828TXN2thioredoxin 2ENSG00000100348609063
26450.16084.1191.7170.086980.8193-4.242645GCKglucokinase (hexokinase 4)ENSG00000106633125851, 125853, 138079, 602485, 606176, 606391
271650.43365.1812.3510.01940.7454-3.20427165GLS2glutaminase 2 (liver, mitochondrial)ENSG00000135423606365
27460.36298.6541.5870.11360.8236-4.4142746GLUD1glutamate dehydrogenase 1ENSG00000148672138130, 606762
2750.36065.0971.9530.051750.8143-3.891275AMTaminomethyltransferaseENSG00000145020238310, 605899
290930.29199.5641.6290.10430.8236-4.35929093MRPL22mitochondrial ribosomal protein L22ENSG00000082515611835
29883-0.36189.837-2.7860.0056760.6175-2.31329883CNOT7CCR4-NOT transcription complex, subunit 7ENSG00000198791604913
29928-0.42237.952-2.3530.019280.744-3.229928TIMM22translocase of inner mitochondrial membrane 22 homolog (yeast)ENSG00000177370607251
30300.51069.5561.5870.11350.8236-4.4133030HADHAhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunitENSG00000084754600890, 609015, 609016
3100.151712.341.770.07770.819-4.165310ANXA7annexin A7ENSG00000138279186360
32570.29634.6641.7330.084050.8193-4.2173257HPS1Hermansky-Pudlak syndrome 1ENSG00000107521203300, 604982
33-0.20943.987-2.2830.023170.7684-3.33133ACADLacyl-CoA dehydrogenase, long chainENSG00000115361201460, 609576
3313-0.3968.47-2.0340.042820.795-3.7613313HSPA9heat shock 70kDa protein 9 (mortalin)ENSG00000113013600548
3329-0.276513.02-2.7080.0071530.6722-2.4833329HSPD1heat shock 60kDa protein 1 (chaperonin)ENSG00000144381118190, 605280, 612233
3840.50415.7422.2160.027440.7684-3.45384ARG2arginase, type IIENSG00000081181107830
41280.68657.2541.680.094070.8193-4.2924128MAOAmonoamine oxidase AENSG00000189221300615, 309850
41511.3535.732.5460.011390.6901-2.8224151MBmyoglobinENSG00000198125160000
43530.25184.2841.7490.08130.819-4.1954353MPOmyeloperoxidaseENSG00000005381104300, 254600, 606989
4528-0.297310.07-1.6640.097240.8193-4.3134528MTIF2mitochondrial translational initiation factor 2ENSG00000085760603766
4580-0.290910.06-1.6220.10580.8236-4.3684580MTX1metaxin 1ENSG00000173171600605
4683-0.48459.718-2.720.0069150.6612-2.4584683NBNnibrinENSG00000104320251260, 602667
47130.14764.0391.6150.10740.8236-4.3784713NDUFB7NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDaENSG00000099795603842
4718-0.204912.4-1.7020.089840.8193-4.2614718NDUFC2NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDaENSG00000151366603845
47190.193710.21.7750.076930.819-4.1594719NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)ENSG00000023228157655, 252010
47220.302110.661.8810.060890.8143-4.0014722NDUFS3NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)ENSG00000213619256000, 603846
50180.549110.243.2120.0014610.4022-1.3055018OXA1Loxidase (cytochrome c) assembly 1-likeENSG00000155463601066
51116-0.41318.376-1.9790.048740.8101-3.8551116MRPS2mitochondrial ribosomal protein S2ENSG00000122140611971
53030.3496.2561.6690.096230.8193-4.3065303PIN4protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)ENSG00000102309300252
5390.26412.512.5320.011860.6901-2.851539ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunitENSG00000241837600828
54280.21044.0422.0480.041440.7924-3.7385428POLGpolymerase (DNA directed), gammaENSG00000140521157640, 174763, 203700, 258450, 603041, 607459, 613662
54420.21164.1621.7220.086190.8193-4.2345442POLRMTpolymerase (RNA) mitochondrial (DNA directed)ENSG00000099821601778
54977-0.30388.771-2.460.014480.7142-2.99554977SLC25A38solute carrier family 25, member 38ENSG00000144659205950, 610819
55173-0.224110.25-1.9310.054460.8143-3.92655173MRPS10mitochondrial ribosomal protein S10ENSG00000048544611976
55703-0.52159.323-3.1210.0019780.4195-1.53255703POLR3Bpolymerase (RNA) III (DNA directed) polypeptide BENSG00000013503614366, 614381
55800.49477.4781.9980.046670.8055-3.825580PRKCDprotein kinase C, deltaENSG00000163932176977
56997-0.34738.676-2.140.033180.7815-3.58456997ADCK3aarF domain containing kinase 3ENSG00000163050606980, 607426, 612016
57404-0.41696.777-2.2220.027040.7684-3.4457404CYP20A1cytochrome P450, family 20, subfamily A, polypeptide 1ENSG00000119004NA
587-0.33377.354-1.6610.097790.8193-4.317587BCAT2branched chain amino-acid transaminase 2, mitochondrialENSG00000105552113530
5930.33787.1091.9510.051990.8143-3.894593BCKDHAbranched chain keto acid dehydrogenase E1, alpha polypeptideENSG00000255730, ENSG00000248098248600, 608348
594-0.38766.038-2.0730.039010.7924-3.696594BCKDHBbranched chain keto acid dehydrogenase E1, beta polypeptideENSG00000083123248600, 248611
596-0.34474.863-1.8830.060660.8143-3.999596BCL2B-cell CLL/lymphoma 2ENSG00000171791151430
598-0.68849.808-3.1740.001660.4159-1.401598BCL2L1BCL2-like 1ENSG00000171552600039
617-0.52468.682-2.5410.011570.6901-2.833617BCS1LBCS1-like (S. cerevisiae)ENSG00000074582124000, 256000, 262000, 603358, 603647
61830.27994.451.8120.071010.819-4.1056183MRPS12mitochondrial ribosomal protein S12ENSG00000128626603021
638750.27199.951.6490.10020.822-4.33363875MRPL17mitochondrial ribosomal protein L17ENSG00000158042611830
63890.200910.721.8230.069370.819-4.0896389SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)ENSG00000073578252011, 256000, 600857, 613642, 614165
6390-0.21154.573-1.690.091990.8193-4.2776390SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)ENSG00000117118115310, 171300, 185470, 606764, 606864, 612359
63910.66659.1171.6530.09940.8206-4.3286391SDHCsuccinate dehydrogenase complex, subunit C, integral membrane protein, 15kDaENSG00000143252602413, 605373, 606764, 606864
64216-0.279810.06-1.8580.06410.8143-4.03664216TFB2Mtranscription factor B2, mitochondrialENSG00000162851607055
6461-0.50887.227-1.9910.047360.8086-3.836461SHBSrc homology 2 domain containing adaptor protein BENSG00000107338600314
64963-0.38335.053-1.9550.051560.8135-3.88864963MRPS11mitochondrial ribosomal protein S11ENSG00000181991611977
65050.33714.5542.2560.024770.7684-3.3786505SLC1A1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1ENSG00000106688133550
6648-0.24073.957-2.6690.0080190.6901-2.5666648SOD2superoxide dismutase 2, mitochondrialENSG00000112096147460, 612634
7084-0.35875.619-1.810.07130.819-4.1087084TK2thymidine kinase 2, mitochondrialENSG00000166548188250, 251880, 609560
74190.49.6941.8310.068070.819-4.0777419VDAC3voltage-dependent anion channel 3ENSG00000078668610029
7531-0.545610.74-2.0750.038890.7924-3.6947531YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptideENSG00000108953247200, 605066
7880.35327.391.8630.06340.8143-4.029788SLC25A20solute carrier family 25 (carnitine/acylcarnitine translocase), member 20ENSG00000178537212138, 613698
79751-0.50146.848-2.2780.023450.7684-3.33979751SLC25A22solute carrier family 25 (mitochondrial carrier: glutamate), member 22ENSG00000177542609302, 609304
8034-0.30025.21-1.9320.054370.8143-3.9258034SLC25A16solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16ENSG00000122912139080
8470.6638.2652.0540.040890.7924-3.729847CATcatalaseENSG00000121691115500, 614097
86040.40088.5892.4780.013750.7085-2.9588604SLC25A12solute carrier family 25 (mitochondrial carrier, Aralar), member 12ENSG00000115840603667, 612949
90160.63287.3181.7760.076790.819-4.1579016SLC25A14solute carrier family 25 (mitochondrial carrier, brain), member 14ENSG00000102078300242
91310.30869.111.8830.060640.8143-3.9999131AIFM1apoptosis-inducing factor, mitochondrion-associated, 1ENSG00000156709300169, 300816
9578-0.62026.968-1.7320.084330.8193-4.229578CDC42BPBCDC42 binding protein kinase beta (DMPK-like)ENSG00000198752614062
9580.17944.3871.8040.072260.819-4.117958CD40CD40 molecule, TNF receptor superfamily member 5ENSG00000101017109535, 606843