AFA results for: tdrugda4PC3

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Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
GO GO:0005515	View Gene Set	8.872e-10	8146	1.185e-05	1	protein binding	amigo.geneontol...
GO GO:0005622	View Gene Set	3.842e-09	11329	1.373e-05	2	intracellular	amigo.geneontol...
GO GO:0005737	View Gene Set	4.112e-09	7676	1.373e-05	2	cytoplasm	amigo.geneontol...
GO GO:0044424	View Gene Set	2.652e-09	10976	1.373e-05	2	intracellular part	amigo.geneontol...
GO GO:0043227	View Gene Set	2.46e-08	8383	5.488e-05	5	membrane-bounded organelle	amigo.geneontol...
GO GO:0043231	View Gene Set	2.465e-08	8376	5.488e-05	5	intracellular membrane-bounded organelle	amigo.geneontol...
GO GO:0043226	View Gene Set	8.12e-08	9360	0.0001356	7	organelle	amigo.geneontol...
GO GO:0043229	View Gene Set	7.753e-08	9346	0.0001356	7	intracellular organelle	amigo.geneontol...
GO GO:0044237	View Gene Set	3.739e-07	7431	0.0005551	9	cellular metabolic process	amigo.geneontol...
GO GO:0008152	View Gene Set	5.116e-07	8439	0.0006835	10	metabolic process	amigo.geneontol...
GO GO:0044444	View Gene Set	7.563e-06	5184	0.009186	11	cytoplasmic part	amigo.geneontol...
GO GO:0009987	View Gene Set	9.247e-06	11620	0.01029	12	cellular process	amigo.geneontol...
GO GO:0048646	View Gene Set	1.198e-05	472	0.01231	13	anatomical structure formation involved in morphogenesis	amigo.geneontol...
GO GO:0006996	View Gene Set	2.25e-05	1501	0.02147	14	organelle organization	amigo.geneontol...
GO GO:0044422	View Gene Set	2.977e-05	5089	0.02652	15	organelle part	amigo.geneontol...
GO GO:0044238	View Gene Set	3.33e-05	7629	0.02655	16	primary metabolic process	amigo.geneontol...
GO GO:0044446	View Gene Set	3.379e-05	5019	0.02655	16	intracellular organelle part	amigo.geneontol...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Broad NUYTTEN_EZH2_TARGETS_UP	View Gene Set	2.262e-10	944	5.41e-07	1	Genes up-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [Gene ID=2146] by RNAi.	www.broad.mit.e...
Broad GRADE_COLON_CANCER_UP	View Gene Set	9.218e-10	711	1.102e-06	2	Up-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples.	www.broad.mit.e...
Broad DELYS_THYROID_CANCER_UP	View Gene Set	3.709e-08	397	2.957e-05	3	Genes up-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue.	www.broad.mit.e...
Broad NUYTTEN_NIPP1_TARGETS_DN	View Gene Set	5.683e-08	758	3.399e-05	4	Genes down-regulated in PC3 cells (prostate cancer) after knockdown of NIPP1 [Gene ID=5511] by RNAi.	www.broad.mit.e...
Broad ENK_UV_RESPONSE_KERATINOCYTE_UP	View Gene Set	9.899e-08	517	4.736e-05	5	Genes up-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation.	www.broad.mit.e...
Broad DANG_BOUND_BY_MYC	View Gene Set	2.7e-07	1045	0.0001076	6	Genes whose promoters are bound by MYC [Gene ID=4609] according to MYC Target Gene Database.	www.broad.mit.e...
Broad LOPEZ_MBD_TARGETS	View Gene Set	4.583e-07	855	0.0001566	7	Genes up-regulated in HeLa cells (cervical cancer) after simultaneus knockdown of all three MBD (methyl-CpG binding domain) proteins MeCP2 MBD1 and MBD2 [Gene ID=4204 4152 8932] by RNAi.	www.broad.mit.e...
Broad SENESE_HDAC1_TARGETS_UP	View Gene Set	6.426e-07	427	0.0001921	8	Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [Gene ID=3065] by RNAi.	www.broad.mit.e...
Broad CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN	View Gene Set	1.037e-06	444	0.0002756	9	Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones.	www.broad.mit.e...
Broad BENPORATH_MYC_MAX_TARGETS	View Gene Set	1.826e-06	768	0.0004368	10	Set 'Myc targets2': targets of c-Myc [Gene ID=4609] and Max [Gene ID=4149] identified by ChIP on chip in a Burkitt???s lymphoma cell line; overlap set.	www.broad.mit.e...
Broad WANG_SMARCE1_TARGETS_DN	View Gene Set	4.129e-06	329	0.0008979	11	Genes down-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [Gene ID=6605] off a retroviral vector.	www.broad.mit.e...
Broad NUYTTEN_NIPP1_TARGETS_UP	View Gene Set	7.783e-06	657	0.001551	12	Genes up-regulated in PC3 cells (prostate cancer) after knockdown of NIPP1 [Gene ID=5511] by RNAi.	www.broad.mit.e...
Broad CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN	View Gene Set	1.037e-05	140	0.001907	13	Genes down-regulated in reverted NIH3T3 cells (fibroblasts transformed by activated KRAS [Gene ID=3845] which then reverted to normal cells upon stable over-expression of a dominant negative form of CDC25 [Gene ID=5923]) vs normal fibroblasts.	www.broad.mit.e...
Broad FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	View Gene Set	1.232e-05	532	0.001964	14	Genes diffierentially expressed in kidney biopsies from patients with well functioning kidneys more than 1-year post transplant compared to the biopsies from normal living kidney donors.	www.broad.mit.e...
Broad MOOTHA_MITOCHONDRIA	View Gene Set	1.202e-05	433	0.001964	14	Mitochondrial genes	www.broad.mit.e...
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP	View Gene Set	1.417e-05	469	0.002118	16	Genes up-regulated in lymphoblastoid cells from the European population compared to those from the Asian population.	www.broad.mit.e...
Broad GARY_CD5_TARGETS_UP	View Gene Set	2.621e-05	463	0.003134	17	Genes up-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector.	www.broad.mit.e...
Broad CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN	View Gene Set	2.58e-05	47	0.003134	17	Genes down-regulated in basal-like breast cancer cell lines as compared to the mesenchymal-like ones.	www.broad.mit.e...
Broad SENESE_HDAC3_TARGETS_UP	View Gene Set	2.337e-05	471	0.003134	17	Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC3 [Gene ID=8841] by RNAi.	www.broad.mit.e...
Broad HAMAI_APOPTOSIS_VIA_TRAIL_UP	View Gene Set	2.478e-05	328	0.003134	17	Genes up-regulated in T1 cells (primary melanoma sensitive to TRAIL [Gene ID=8743]) compared to G1 cells (metastatic melanoma resistant to TRAIL).	www.broad.mit.e...
Broad SENESE_HDAC1_AND_HDAC2_TARGETS_UP	View Gene Set	3.46e-05	224	0.003941	21	Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of both HDAC1 and HDAC2 [Gene ID=3065 3066] by RNAi.	www.broad.mit.e...
Broad GEORGES_TARGETS_OF_MIR192_AND_MIR215	View Gene Set	3.727e-05	809	0.004052	22	Genes down-regulated in HCT116 cells (colon cancer) by expression of MIR192 or MIR215 [Gene ID=406967 406997] at 24 h.	www.broad.mit.e...
Broad BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_DN	View Gene Set	4.515e-05	30	0.004696	23	Genes down-regulated in ALL (acute lymphoblastic leukemia) patients who developed t-ML (treatment related myeloid leukemia).	www.broad.mit.e...
Broad ONKEN_UVEAL_MELANOMA_UP	View Gene Set	5.117e-05	739	0.005044	24	Genes up-regulated in uveal melanoma: class 2 vs class 1 tumors.	www.broad.mit.e...
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	View Gene Set	5.42e-05	825	0.005044	24	Genes down-regulated in fibroblasts expressing mutant forms of ERCC3 [Gene ID=2071] after UV irradiation.	www.broad.mit.e...
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	View Gene Set	5.904e-05	418	0.005044	24	Common down-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [Gene ID=2071] after UVC irradiation.	www.broad.mit.e...
Broad DAIRKEE_TERT_TARGETS_UP	View Gene Set	5.567e-05	317	0.005044	24	Genes up-regulated in non-spontaneously immortalizing (NSI) primary breast cancer tumor cultures upon expression of TERT [Gene ID=7015] off a retroviral vector.	www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP	View Gene Set	5.703e-05	716	0.005044	24	Genes up-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h.	www.broad.mit.e...
Broad AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G	View Gene Set	6.527e-05	151	0.005363	29	Genes with basal expression distinguishing NCI-60 cell lines with poor survival after 2 Gy gamma irradiation.	www.broad.mit.e...
Broad ZUCCHI_METASTASIS_DN	View Gene Set	6.727e-05	28	0.005363	29	The 50 most down-regulated genes in primary invasive breast dutcal carcinoma (IDC) or lymph node metastases compared to normal mammary epithelium.	www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_18HR_UP	View Gene Set	7.608e-05	175	0.005871	31	Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 18 h time point that were not up-regulated at the previous time point 16 h.	www.broad.mit.e...
Broad DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP	View Gene Set	8.153e-05	1353	0.006094	32	Genes up-regulated in CD34+ [Gene ID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients compared to those from normal donors.	www.broad.mit.e...
Broad BENPORATH_SOX2_TARGETS	View Gene Set	8.744e-05	704	0.006338	33	Set 'Sox2 targets': genes upregulated and identified by ChIP on chip as SOX2 [Gene ID=6657] transcription factor targets in human embryonic stem cells.	www.broad.mit.e...
Broad PODAR_RESPONSE_TO_ADAPHOSTIN_UP	View Gene Set	9.322e-05	140	0.006558	34	Up-regulated genes in MM1.S cells (multiple myeloma) treated with adaphostin [PubChem=387042] a tyrosine kinase inhibitor with anticancer properties.	www.broad.mit.e...
Broad TIEN_INTESTINE_PROBIOTICS_24HR_UP	View Gene Set	0.0001124	537	0.006894	35	Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h.	www.broad.mit.e...
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN	View Gene Set	0.0001082	571	0.006894	35	Genes down-regulated in lymphoblastoid cells from the European population compared to those from the Asian population.	www.broad.mit.e...
Broad FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN	View Gene Set	0.0001095	532	0.006894	35	Genes differentially expressed in kidney biopsies from patients with acute transplant rejection compared to the biopsies from patients with well functioning kidneys more than 1-year post transplant.	www.broad.mit.e...
Broad HONMA_DOCETAXEL_RESISTANCE	View Gene Set	0.0001104	30	0.006894	35	Genes up-regulated in MCF7-ADR cell line (breast cancer) resistant to docetaxel [PubChem=148124].	www.broad.mit.e...
Broad MOOTHA_HUMAN_MITODB_6_2002	View Gene Set	0.0001054	420	0.006894	35	Mitochondrial genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets.	www.broad.mit.e...
Broad RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN	View Gene Set	0.0001366	361	0.008169	40	Down-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors.	www.broad.mit.e...
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP	View Gene Set	0.0001436	869	0.00838	41	Genes up-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h.	www.broad.mit.e...
Broad MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN	View Gene Set	0.0001479	212	0.008425	42	Genes down-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199].	www.broad.mit.e...
Broad NUYTTEN_EZH2_TARGETS_DN	View Gene Set	0.0001518	859	0.008442	43	Genes down-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [Gene ID=2146] by RNAi.	www.broad.mit.e...
Broad SENESE_HDAC1_TARGETS_DN	View Gene Set	0.0001658	235	0.008695	44	Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [Gene ID=3065] by RNAi.	www.broad.mit.e...
Broad WINTER_HYPOXIA_METAGENE	View Gene Set	0.0001708	216	0.008695	44	Genes regulated by hypoxia based on literature searches.	www.broad.mit.e...
Broad SWEET_LUNG_CANCER_KRAS_UP	View Gene Set	0.0001682	436	0.008695	44	Genes up-regulated in the mouse lung cancer model with mutated KRAS [Gene ID=3845].	www.broad.mit.e...
Broad SESTO_RESPONSE_TO_UV_C4	View Gene Set	0.00017	19	0.008695	44	Cluster 4: genes changed in primary keratinocytes by UVB irradiation.	www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP	View Gene Set	0.0001923	589	0.009304	48	Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue.	www.broad.mit.e...
Broad BERENJENO_TRANSFORMED_BY_RHOA_UP	View Gene Set	0.0001873	485	0.009304	48	Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [Gene ID=387] off plasmid vector.	www.broad.mit.e...
Broad CAIRO_HEPATOBLASTOMA_CLASSES_UP	View Gene Set	0.0001945	577	0.009304	48	Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1).	www.broad.mit.e...
Broad STEIN_ESRRA_TARGETS	View Gene Set	0.0002088	508	0.009793	51	Genes regulated by ESRRA [Gene ID=2101] in MCF-7 cells (breast cancer).	www.broad.mit.e...
Broad BORCZUK_MALIGNANT_MESOTHELIOMA_UP	View Gene Set	0.0002238	290	0.0102	52	Genes up-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma.	www.broad.mit.e...
Broad GU_PDEF_TARGETS_DN	View Gene Set	0.0002261	31	0.0102	52	Integrin VEGF Wnt and TGF-?? signaling pathway genes down-regulated in PC-3 cells (prostate cancer) after knockdown of PDEF [Gene ID=25803] by RNAi.	www.broad.mit.e...
Broad RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP	View Gene Set	0.0002559	75	0.01134	54	Genes up-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids.	www.broad.mit.e...
Broad BENPORATH_PROLIFERATION	View Gene Set	0.0002693	140	0.01163	55	Set 'Proliferation Cluster': genes defined in human breast tumor expression data.	www.broad.mit.e...
Broad SMID_BREAST_CANCER_BASAL_UP	View Gene Set	0.0002722	629	0.01163	55	Genes up-regulated in basal subtype of breast cancer samles.	www.broad.mit.e...
Broad FARMER_BREAST_CANCER_BASAL_VS_LULMINAL	View Gene Set	0.0002882	317	0.0121	57	Genes which best discriminated between two groups of breast cancer according to the status of ESR1 and AR [Gene ID=2099 367]: basal (ESR1- AR-) and luminal (ESR1+ AR+).	www.broad.mit.e...
Broad BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	View Gene Set	0.0003114	783	0.01284	58	Genes up-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress.	www.broad.mit.e...
Broad ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP	View Gene Set	0.0003234	208	0.01311	59	Genes up-regulated in BxPC3 cells (pancreatic cancer) after treatment with TNF [Gene ID=7124] or IKI-1 an inhibitor of I?B kinase (IKK).	www.broad.mit.e...
Broad HOLLMAN_APOPTOSIS_VIA_CD40_UP	View Gene Set	0.0003623	193	0.01384	60	Genes up-regulated in DLBCL (diffuse large B-cell lymphoma) cell lines sensitive to stimulation of CD40 [Gene ID=958] relative to the resistant ones.	www.broad.mit.e...
Broad LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP	View Gene Set	0.0003645	79	0.01384	60	Genes up-regulated between two breast carcinoma subtypes: metaplastic (MCB) and ductal (DCB).	www.broad.mit.e...
Broad ONDER_CDH1_TARGETS_2_DN	View Gene Set	0.0003512	453	0.01384	60	Genes down-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [Gene ID=999] knockdown by RNAi.	www.broad.mit.e...
Broad GOLDRATH_ANTIGEN_RESPONSE	View Gene Set	0.0003549	315	0.01384	60	Genes up-regulated at the peak of an antigen response of naive CD8+ [Gene ID=925 926] T-cells.	www.broad.mit.e...
Broad SCHLOSSER_SERUM_RESPONSE_DN	View Gene Set	0.0003779	666	0.01412	64	Cluster 4: genes down-regulated in B493-6 cells (B lymphocytes) upon serum stimulation but not affected by MYC [Gene ID=4609].	www.broad.mit.e...
Broad LINDGREN_BLADDER_CANCER_CLUSTER_1_DN	View Gene Set	0.0003934	368	0.01448	65	Genes whose expression profile is specific to Custer I of urothelial cell carcinoma (UCC) tumors.	www.broad.mit.e...
Broad MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS	View Gene Set	0.0004394	36	0.01593	66	Genes expressed in multiple myeloma (MM) patients carrying specific translocations involving the immunoglobulin heavy chain (IGH) locus at 14q32.	www.broad.mit.e...
Broad FERRARI_RESPONSE_TO_FENRETINIDE_UP	View Gene Set	0.0004482	16	0.016	67	Genes up-regulated in HUVEC cells (umbilical vein endothelium) by fenretinide [PubChem=1744].	www.broad.mit.e...
Broad MARTINEZ_RB1_TARGETS_UP	View Gene Set	0.0004611	613	0.01622	68	Genes up-regulated in mice with skin specific knockout of RB1 [Gene ID=5925] by Cre-lox.	www.broad.mit.e...
Broad LAIHO_COLORECTAL_CANCER_SERRATED_DN	View Gene Set	0.0004959	81	0.01719	69	Genes down-regulated in serrated vs conventional colorectal carcinoma (CRC) samples.	www.broad.mit.e...
Broad CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN	View Gene Set	0.0005133	437	0.01754	70	Genes down-regulated in luminal-like breast cancer cell lines compared to the basal-like ones.	www.broad.mit.e...
Broad RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	View Gene Set	0.0005366	681	0.01808	71	Genes up-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue.	www.broad.mit.e...
Broad AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G	View Gene Set	0.0005469	84	0.01817	72	Genes with basal expression distinguishing NCI-60 cell lines with poor survival after 8 Gy gamma irradiation.	www.broad.mit.e...
Broad BLALOCK_ALZHEIMERS_DISEASE_DN	View Gene Set	0.0005655	1209	0.01853	73	Genes down-regulated in brain from patients with Alzheimer's disease.	www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14	View Gene Set	0.0006081	131	0.01966	74	Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 14.	www.broad.mit.e...
Broad BLALOCK_ALZHEIMERS_DISEASE_UP	View Gene Set	0.0006291	1641	0.02006	75	Genes up-regulated in brain from patients with Alzheimer's disease.	www.broad.mit.e...
Broad ONKEN_UVEAL_MELANOMA_DN	View Gene Set	0.0006453	509	0.02031	76	Genes down-regulated in uveal melanoma: class 2 vs class 1 tumors.	www.broad.mit.e...
Broad HINATA_NFKB_TARGETS_FIBROBLAST_UP	View Gene Set	0.000658	66	0.02044	77	Genes up-regulated in primary fibroblast cells by expression of p50 (NFKB1) and p65 (RELA) [Gene ID=4790 5970] components of NFKB.	www.broad.mit.e...
Broad WU_CELL_MIGRATION	View Gene Set	0.0006953	182	0.02086	78	Genes associated with migration rate of 40 human bladder cancer cells.	www.broad.mit.e...
Broad REN_ALVEOLAR_RHABDOMYOSARCOMA_DN	View Gene Set	0.0007012	402	0.02086	78	Genes commonly down-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [Gene ID=5077 2308] fusion.	www.broad.mit.e...
Broad CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5	View Gene Set	0.0007063	446	0.02086	78	The 'group 5 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 but not ERBB2 [Gene ID=2099 2064].	www.broad.mit.e...
Broad SESTO_RESPONSE_TO_UV_C8	View Gene Set	0.0007064	71	0.02086	78	Cluster 8: genes changed in primary keratinocytes by UVB irradiation.	www.broad.mit.e...
Broad GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN	View Gene Set	0.0007493	26	0.02186	82	Genes down-regulated in glioblastoma cell lines displaying spherical growth (cluster-1) compared to those displaying semiadherent or adherent growth phenotype (cluster-2).	www.broad.mit.e...
Broad SENESE_HDAC3_TARGETS_DN	View Gene Set	0.0007778	487	0.02231	83	Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC3 [Gene ID=8841] by RNAi.	www.broad.mit.e...
Broad KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN	View Gene Set	0.0007835	56	0.02231	83	Genes down-regulated in AIDS-related primary effusion lymphoma (PEL) samples compared to other tumor subtypes and normal B lymphocytes.	www.broad.mit.e...
Broad TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP	View Gene Set	0.0008029	20	0.02238	85	Genes up-regulated by RUNX1-RUNX1T1 [Gene ID=861 862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing monocytes.	www.broad.mit.e...
Broad SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6	View Gene Set	0.0008046	435	0.02238	85	Cluster 6 of method A: up-regulation of these genes in patients with non???small cell lung cancer (NSCLC) predicts poor survival outcome.	www.broad.mit.e...
Broad SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM	View Gene Set	0.0008376	154	0.02303	87	Cluster 7: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] and down-regulated by the combination of MYC and serum.	www.broad.mit.e...
Broad AMIT_SERUM_RESPONSE_240_MCF10A	View Gene Set	0.0008683	57	0.0236	88	Genes whose expression peaked at 240 min after stimulation of MCF10A cells with serum.	www.broad.mit.e...
Broad GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN	View Gene Set	0.0008931	45	0.02374	89	Genes down-regulated in quiescent (G0) CD34+ [Gene ID=8842] cells isolated from peripheral blood of CML (chronic myeloid leukemia) patients compared to the quiescent cells from normal donors.	www.broad.mit.e...
Broad SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN	View Gene Set	0.000889	306	0.02374	89	Genes down-regulated in bone relapse of breast cancer.	www.broad.mit.e...
Broad MARKEY_RB1_CHRONIC_LOF_UP	View Gene Set	0.000912	111	0.02397	91	Genes up-regulated in MEF cells (embryonic fibroblasts) isolated from RB1 [Gene ID=5925] knockout mice: chronic loss of function (LOF) of RB1.	www.broad.mit.e...
Broad MARTINEZ_RB1_AND_TP53_TARGETS_UP	View Gene Set	0.001083	539	0.02756	92	Genes up-regulated in mice with skin specific double knockout of both RB1 and TP53 [Gene ID=5925 7157] by Cre-lox.	www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_24HR_UP	View Gene Set	0.001079	146	0.02756	92	Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 24 h time point that were not up-regulated at the previous time point 20 h.	www.broad.mit.e...
Broad MAHAJAN_RESPONSE_TO_IL1A_UP	View Gene Set	0.001079	67	0.02756	92	Genes up-regulated in corneal fibroblasts after treatment with IL1A [Gene ID=3552].	www.broad.mit.e...
Broad THUM_SYSTOLIC_HEART_FAILURE_UP	View Gene Set	0.001105	393	0.02779	95	Genes up-regulated in samples with systolic heart failure compared to normal hearts.	www.broad.mit.e...
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP	View Gene Set	0.001115	70	0.02779	95	Genes from the turquoise module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphocholine (oxPAPC).	www.broad.mit.e...
Broad DAZARD_RESPONSE_TO_UV_NHEK_UP	View Gene Set	0.001144	155	0.02822	97	Genes up-regulated in NHEK cells (normal keratinocytes) by UV-B irradiation.	www.broad.mit.e...
Broad TOMIDA_METASTASIS_UP	View Gene Set	0.001164	20	0.0284	98	Up-regulated genes associated with the acquision of metastatic potential in LNM35 cells (large cell lung cancer).	www.broad.mit.e...
Broad NELSON_RESPONSE_TO_ANDROGEN_UP	View Gene Set	0.00119	81	0.02876	99	Genes up-regulated in LNCaP cells (prostate cancer) in response to synthetic androgen R1881 [PubChem=13766].	www.broad.mit.e...
Broad RODRIGUES_NTN1_TARGETS_DN	View Gene Set	0.001216	151	0.02876	100	Genes down-regulated in HCT8/S11 cells (colon cancer) engineered to stably express NTN1 [Gene ID=1630] off a plasmid vector.	www.broad.mit.e...
Broad GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP	View Gene Set	0.001226	65	0.02876	100	Genes up-regulated in quiescent vs dividing CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors.	www.broad.mit.e...
Broad HUANG_DASATINIB_RESISTANCE_UP	View Gene Set	0.001205	75	0.02876	100	Genes whose expression positively correlated with sensitivity of breast cancer cell lines to dasatinib [PubChem=3062316].	www.broad.mit.e...
Broad NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN	View Gene Set	0.001274	583	0.02958	103	Down-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone.	www.broad.mit.e...
Broad LIU_VMYB_TARGETS_UP	View Gene Set	0.00136	121	0.03128	104	Genes up-regulated in MCF-7 cells (breast cancer) by overexpression of v-MYB oncogenic varian of CMYB [Gene ID=4602] off adenovirus vector.	www.broad.mit.e...
Broad SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN	View Gene Set	0.001457	55	0.03257	105	Genes down-regulated in 293 cells (embryonic kidney) upon expression of KHSV (Kaposi sarcoma???associated herpesvirus) microRNAs.	www.broad.mit.e...
Broad KIM_WT1_TARGETS_12HR_UP	View Gene Set	0.001436	157	0.03257	105	Genes up-regulated in UB27 cells (osteosarcoma) at 12 hr after inducing the expression of a mutated form of WT1 [Gene ID=7490].	www.broad.mit.e...
Broad FAELT_B_CLL_WITH_VH3_21_UP	View Gene Set	0.001456	44	0.03257	105	Genes changed in samples from B-CLL (B-cell chronic lymphocytic leukemia) using the immunoglobulin heavy chain VH3-21 gene.	www.broad.mit.e...
Broad WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP	View Gene Set	0.001535	110	0.034	108	Genes specific to esophageal adenocarcinoma (EAC) relative to normal tissue.	www.broad.mit.e...
Broad GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN	View Gene Set	0.001562	93	0.03429	109	Genes down-regulated in quiescent CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors compared to the dividing cells from CML (chronic myeloid leukemia) patients.	www.broad.mit.e...
Broad CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN	View Gene Set	0.001593	155	0.03464	110	Marker genes down-regulated in the 'unannotated' subclass of hepatocellular carcinoma (HCC) samples.	www.broad.mit.e...
Broad STEIN_ESRRA_TARGETS_UP	View Gene Set	0.001615	368	0.0348	111	Genes up-regulated by ESRRA [Gene ID=2101] only.	www.broad.mit.e...
Broad WONG_EMBRYONIC_STEM_CELL_CORE	View Gene Set	0.001699	331	0.03611	112	The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module.	www.broad.mit.e...
Broad IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR	View Gene Set	0.001706	126	0.03611	112	Genes in the expression cluster 'Late Progenitors Shared': up-regulated in hematopoietic late progenitor cells from adult bone marrow and fetal liver.	www.broad.mit.e...
Broad BIDUS_METASTASIS_UP	View Gene Set	0.001839	203	0.03822	114	Genes up-regulated in endometroid endometrial tumors from patients with lymph node metastases compared to those without the metastases.	www.broad.mit.e...
Broad BIERIE_INFLAMMATORY_RESPONSE_TGFB1	View Gene Set	0.001857	5	0.03822	114	Inflammatory genes down-regulated in mammary carcinoma cells after stimulation with TGFB1 [Gene ID=7040] for 1 hr.	www.broad.mit.e...
Broad LIANG_SILENCED_BY_METHYLATION_UP	View Gene Set	0.001869	20	0.03822	114	Genes up-regulated in LD419 cells (fibroblast) after treatment with decitabine (5-aza-2'-deoxycytidine) [PubChem=451668].	www.broad.mit.e...
Broad SESTO_RESPONSE_TO_UV_C3	View Gene Set	0.00183	20	0.03822	114	Cluster 3: genes changed in primary keratinocytes by UVB irradiation.	www.broad.mit.e...
Broad SENESE_HDAC2_TARGETS_UP	View Gene Set	0.001944	109	0.03858	118	Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC2 [Gene ID=3066] by RNAi.	www.broad.mit.e...
Broad HAHTOLA_MYCOSIS_FUNGOIDES_UP	View Gene Set	0.001956	17	0.03858	118	Genes up-regulated in monocytes isolated from peripheral blood samples of patients with mucosis fungoides compared to those from normal healthy donors.	www.broad.mit.e...
Broad SCHLOSSER_SERUM_RESPONSE_AUGMENTED_BY_MYC	View Gene Set	0.001982	101	0.03858	118	Cluster 2: genes up-regulated in B493-6 cells (B lymphocytes) by serum alone or in combination with MYC [Gene ID=4609] but not by MYC alone.	www.broad.mit.e...
Broad ONDER_CDH1_TARGETS_3_DN	View Gene Set	0.002	52	0.03858	118	Genes down-regulated in HMLE cells (immortalized nontransformed mammary epithelial) cells after loss of function of E-cadhedrin (CDH1) [Gene ID=999] which was achieved either by RNAi knockdown or by expression of a dominan-negative form of CDH1.	www.broad.mit.e...
Broad POTTI_CYTOXAN_SENSITIVITY	View Gene Set	0.001994	32	0.03858	118	Genes predicting sensitivity to cytoxan [PubChem=2907].	www.broad.mit.e...
Broad CHANDRAN_METASTASIS_UP	View Gene Set	0.001958	79	0.03858	118	Genes up-regulated in metastatic tumors from the whole panel of patients with prostate cancer.	www.broad.mit.e...
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13	View Gene Set	0.001917	158	0.03858	118	Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 13.	www.broad.mit.e...
Broad RADMACHER_AML_PROGNOSIS	View Gene Set	0.002058	77	0.03907	125	The 'Bullinger validation signature' [PMID=15084693] used to validate prediction of prognostic outcome of acute myeloid leukemia (AML) patients with a normal karyotype.	www.broad.mit.e...
Broad DANG_MYC_TARGETS_UP	View Gene Set	0.002058	127	0.03907	125	Genes up-regulated by MYC [Gene ID=4609] and whose promoters are bound by MYC according to MYC Target Gene Database.	www.broad.mit.e...
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_UP	View Gene Set	0.002075	301	0.03909	127	Genes up-regulated in fibroblasts expressing mutant forms of ERCC3 [Gene ID=2071] after UV irradiation.	www.broad.mit.e...
Broad STREICHER_LSM1_TARGETS_DN	View Gene Set	0.002123	19	0.03958	128	Genes down-regulated in MCF10A cells (breast cancer) by expression of LSM1 [Gene ID=27257] off a letiviral vector.	www.broad.mit.e...
Broad NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON	View Gene Set	0.002135	150	0.03958	128	Genes within amplicon 8q23-q24 identified in a copy number alterations study of 191 breast tumor samples.	www.broad.mit.e...
Broad HAN_SATB1_TARGETS_DN	View Gene Set	0.002167	320	0.03974	130	Genes down-regulated in MDA-MB-231 cells (breast cancer) after knockdown of SATB1 [Gene ID=6304] by RNAi.	www.broad.mit.e...
Broad KAYO_CALORIE_RESTRICTION_MUSCLE_UP	View Gene Set	0.002176	69	0.03974	130	Upregulated in the vastus lateralis muscle of middle aged rhesus monkeys subjected to caloric restriction since young adulthood vs age matched controls	www.broad.mit.e...
Broad MARSON_FOXP3_TARGETS_STIMULATED_UP	View Gene Set	0.002203	22	0.03993	132	Genes with promoters bound by FOXP3 [Gene ID=50943] dependent on it and changed in hybridoma cells stimulated by PMA [PubChem=4792] and ionomycin [PubChem=3733].	www.broad.mit.e...
Broad LIAO_METASTASIS	View Gene Set	0.002239	513	0.04028	133	Genes up-regulated in the samples with intrahepatic metastatic hepatocellular carcinoma (HCC) vs primary HCC.	www.broad.mit.e...
Broad CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP	View Gene Set	0.002336	50	0.0417	134	Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by activated KRAS [Gene ID=3845] vs those reverted to normal cells upon over-expression of a dominant negative form of CDC25 [Gene ID=5923].	www.broad.mit.e...
Broad FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP	View Gene Set	0.002519	539	0.04401	135	Genes up-regulated in monocyte-derived dendritic cells (MDDC) after stimulation with galecin-1 (lectin LGALS1) [Gene ID=3956] compared to that with bacterial lipopolysaccharide (LPS).	www.broad.mit.e...
Broad KIM_WT1_TARGETS_DN	View Gene Set	0.002509	431	0.04401	135	Genes down-regulated in UB27 cells (osteosarcoma) at any time point after inducing the expression of a mutant form of WT1 [Gene ID=7490].	www.broad.mit.e...
Broad BILD_E2F3_ONCOGENIC_SIGNATURE	View Gene Set	0.00252	222	0.04401	135	Genes selected in supervised analyses to discriminate cells expressing E2F3 [Gene ID=1871] from control cells expressing GFP.	www.broad.mit.e...
Broad HARRIS_HYPOXIA	View Gene Set	0.002561	79	0.0444	138	Genes known to be induced by hypoxia	www.broad.mit.e...
Broad ONDER_CDH1_TARGETS_1_DN	View Gene Set	0.00262	161	0.04509	139	Genes down-regulated in HMLE cells (mmortalized nontransformed mammary epithelial) by expression of a dominant-negative form of E-cadhedrin (CDH1) [Gene ID=999].	www.broad.mit.e...
Broad DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP	View Gene Set	0.002657	247	0.04539	140	Genes up-regulated in RD cells (embryonal rhabdomyosarcoma ERMS) by expression of PAX3- or PAX7-FOXO1 [Gene ID=5077 5081 2308] fusions off retroviral vectors.	www.broad.mit.e...
Broad BROWNE_HCMV_INFECTION_14HR_DN	View Gene Set	0.002818	289	0.0478	141	Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not down-regulated at the previous time point 12 h.	www.broad.mit.e...
Broad IGARASHI_ATF4_TARGETS_UP	View Gene Set	0.002944	6	0.04945	142	Genes up-regulated in A549 cells (lung cancer) after knockdown of ATF4 [Gene ID=468] by RNAi.	www.broad.mit.e...
Broad CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP	View Gene Set	0.002956	116	0.04945	142	Genes up-regulated in transformed NIH3T3 cells (fibroblasts transformed by activated KRAS [Gene ID=3845]) vs normal cells.	www.broad.mit.e...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Broad REACTOME_RNA_POLYMERASE_I_PROMOTER_OPENING	View Gene Set	1.358e-05	59	0.005841	1	Genes involved in RNA Polymerase I Promoter Opening	www.broad.mit.e...
Broad REACTOME_TELOMERE_MAINTENANCE	View Gene Set	7.802e-05	77	0.01118	2	Genes involved in Telomere Maintenance	www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_III_AND_MITOCHONDRIAL_TRANSCRIPTION	View Gene Set	5.477e-05	120	0.01118	2	Genes involved in RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription	www.broad.mit.e...
Broad REACTOME_TRANSCRIPTION	View Gene Set	0.000216	188	0.02322	4	Genes involved in Transcription	www.broad.mit.e...
Broad REACTOME_DIABETES_PATHWAYS	View Gene Set	0.0003326	383	0.02384	5	Genes involved in Diabetes pathways	www.broad.mit.e...
Broad REACTOME_PACKAGING_OF_TELOMERE_ENDS	View Gene Set	0.0002924	49	0.02384	5	Genes involved in Packaging Of Telomere Ends	www.broad.mit.e...
Broad REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION	View Gene Set	0.0005519	161	0.02966	7	Genes involved in Glucose Regulation of Insulin Secretion	www.broad.mit.e...
Broad REACTOME_RNA_POLYMERASE_I_PROMOTER_CLEARANCE	View Gene Set	0.0004885	82	0.02966	7	Genes involved in RNA PolymerasePromoter Clearance	www.broad.mit.e...
Broad REACTOME_REGULATION_OF_INSULIN_SECRETION	View Gene Set	0.0007345	212	0.03509	9	Genes involved in Regulation of Insulin Secretion	www.broad.mit.e...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Broad GGGCGGR_V$SP1_Q6	View Gene Set	3.145e-06	2120	0.001934	1	Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGGCGGR which matches annotation for SP1: Sp1 transcription factor	www.broad.mit.e...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Broad MORF_ACP1	View Gene Set	7.075e-05	178	0.01535	1	Neighborhood of ACP1	www.broad.mit.e...
Broad MORF_CSNK2B	View Gene Set	7.191e-05	256	0.01535	1	Neighborhood of CSNK2B	www.broad.mit.e...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Broad module_321	View Gene Set	3.292e-07	107	0.0001495	1	Genes in module_321	www.broad.mit.e...
Broad module_198	View Gene Set	4.047e-06	288	0.0009186	2	Genes in module_198	www.broad.mit.e...
Broad module_349	View Gene Set	4.137e-05	17	0.00626	3	Genes in module_349	www.broad.mit.e...
Broad module_18	View Gene Set	6.105e-05	434	0.006929	4	Genes in module_18	www.broad.mit.e...
Broad module_98	View Gene Set	0.0001184	375	0.01076	5	Genes in module_98	www.broad.mit.e...
Broad module_252	View Gene Set	0.0001599	224	0.0121	6	Genes in module_252	www.broad.mit.e...
Broad module_17	View Gene Set	0.0002417	351	0.01567	7	Genes in module_17	www.broad.mit.e...
Broad module_3	View Gene Set	0.0004018	374	0.0228	8	Genes in module_3	www.broad.mit.e...
Broad module_226	View Gene Set	0.0007524	27	0.03795	9	Genes in module_226	www.broad.mit.e...
Broad module_78	View Gene Set	0.0009245	20	0.04197	10	Genes in module_78	www.broad.mit.e...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Broad BIOPOLYMER_METABOLIC_PROCESS	View Gene Set	6.829e-07	1623	0.0005634	1	Genes annotated by the GO term GO:0043283. The chemical reactions and pathways involving biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins.	www.broad.mit.e...
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS	View Gene Set	2.688e-05	1197	0.01109	2	Genes annotated by the GO term GO:0006139. The chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids.	www.broad.mit.e...
Broad TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER	View Gene Set	6.843e-05	449	0.01882	3	Genes annotated by the GO term GO:0006366. The synthesis of RNA from a DNA template by RNA polymerase II (Pol II) originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).	www.broad.mit.e...
Broad RNA_METABOLIC_PROCESS	View Gene Set	0.0001616	801	0.02222	4	Genes annotated by the GO term GO:0016070. The chemical reactions and pathways involving RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage.	www.broad.mit.e...
Broad ANATOMICAL_STRUCTURE_MORPHOGENESIS	View Gene Set	0.0001433	375	0.02222	4	Genes annotated by the GO term GO:0009653. The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.	www.broad.mit.e...
Broad RNA_BIOSYNTHETIC_PROCESS	View Gene Set	0.0001594	625	0.02222	4	Genes annotated by the GO term GO:0032774. The chemical reactions and pathways resulting in the formation of RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers.	www.broad.mit.e...
Broad TRANSCRIPTION_DNA_DEPENDENT	View Gene Set	0.0002189	623	0.0258	7	Genes annotated by the GO term GO:0006351. The synthesis of RNA on a template of DNA.	www.broad.mit.e...
Broad TRANSCRIPTION	View Gene Set	0.0003649	738	0.03763	8	Genes annotated by the GO term GO:0006350. The synthesis of either RNA on a template of DNA or DNA on a template of RNA.	www.broad.mit.e...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Broad CYTOPLASM	View Gene Set	7.895e-07	2054	0.0001839	1	Genes annotated by the GO term GO:0005737. All of the contents of a cell excluding the plasma membrane and nucleus but including other subcellular structures.	www.broad.mit.e...
Broad NUCLEUS	View Gene Set	3.806e-06	1353	0.0004434	2	Genes annotated by the GO term GO:0005634. A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells the nucleus contains all of the cell's chromosomes except the organellar chromosomes and is the site of RNA synthesis and processing. In some species or in specialized cell types RNA metabolism or DNA replication may be absent.	www.broad.mit.e...
Broad MACROMOLECULAR_COMPLEX	View Gene Set	0.0002517	914	0.01596	3	Genes annotated by the GO term GO:0032991. A stable assembly of two or more macromolecules i.e. proteins nucleic acids carbohydrates or lipids in which the constituent parts function together.	www.broad.mit.e...
Broad PROTEIN_COMPLEX	View Gene Set	0.0002741	799	0.01596	3	Genes annotated by the GO term GO:0043234. Any protein group composed of two or more subunits which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups.	www.broad.mit.e...
Broad MITOCHONDRION	View Gene Set	0.0004528	335	0.0211	5	Genes annotated by the GO term GO:0005739. A semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.	www.broad.mit.e...
Broad CYTOPLASMIC_PART	View Gene Set	0.0007019	1350	0.02703	6	Genes annotated by the GO term GO:0044444. Any constituent part of the cytoplasm all of the contents of a cell excluding the plasma membrane and nucleus but including other subcellular structures.	www.broad.mit.e...
Broad INTRACELLULAR_ORGANELLE_PART	View Gene Set	0.0008121	1144	0.02703	6	Genes annotated by the GO term GO:0044446. A constituent part of an intracellular organelle an organized structure of distinctive morphology and function occurring within the cell. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane.	www.broad.mit.e...
Broad ORGANELLE_PART	View Gene Set	0.001092	1149	0.0318	8	Genes annotated by the GO term GO:0044422. Any constituent part of an organelle an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane.	www.broad.mit.e...
Broad KINETOCHORE	View Gene Set	0.001582	25	0.04096	9	Genes annotated by the GO term GO:0000776. A multisubunit complex that is located at the pericentric region of DNA and provides an attachment point for the spindle microtubules.	www.broad.mit.e...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
PMID 12757711	View Gene Set	8.795e-07	18	0.002205	1	Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase.	www.ncbi.nlm.ni...
PMID 16283522	View Gene Set	1.86e-06	18	0.002331	2	Inhibition of core histones acetylation by carcinogenic nickel(II).	www.ncbi.nlm.ni...
PMID 16713563	View Gene Set	5.255e-06	19	0.004391	3	Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II.	www.ncbi.nlm.ni...
PMID 11113628	View Gene Set	1.659e-05	11	0.01039	4	Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation.	www.ncbi.nlm.ni...
PMID 11689053	View Gene Set	5.128e-05	70	0.02143	5	Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA.	www.ncbi.nlm.ni...
PMID 19795399	View Gene Set	5.039e-05	10	0.02143	5	Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group.	www.ncbi.nlm.ni...
PMID 10064132	View Gene Set	7.984e-05	14	0.02851	7	The human H2A and H2B histone gene complement.	www.ncbi.nlm.ni...
PMID 12665801	View Gene Set	9.099e-05	261	0.02851	7	Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.	www.ncbi.nlm.ni...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null PS00357	View Gene Set	8.737e-08	19	6.422e-05	1	HISTONE_H2B	expasy.org/pros...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null EC:3.1.3.16	View Gene Set	8.915e-06	24	0.001409	1	Phosphoprotein phosphatase	expasy.org/enzy...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null Glypican pathway	View Gene Set	5.388e-06	937	0.001002	1	NCI_NATURE - Glypican pathway gene set	www.pathwaycomm...
Null Glypican 1 network	View Gene Set	8.588e-05	796	0.007987	2	NCI_NATURE - Glypican 1 network gene set	www.pathwaycomm...
Null ErbB1 downstream signaling	View Gene Set	0.0005817	812	0.01768	3	NCI_NATURE - ErbB1 downstream signaling gene set	www.pathwaycomm...
Null EGF receptor (ErbB1) signaling pathway	View Gene Set	0.0005817	812	0.01768	3	NCI_NATURE - EGF receptor (ErbB1) signaling pathway gene set	www.pathwaycomm...
Null Validated targets of C-MYC transcriptional activation	View Gene Set	0.0007006	80	0.01768	3	NCI_NATURE - Validated targets of C-MYC transcriptional activation gene set	www.pathwaycomm...
Null TRAIL signaling pathway	View Gene Set	0.0007602	686	0.01768	3	NCI_NATURE - TRAIL signaling pathway gene set	www.pathwaycomm...
Null Internalization of ErbB1	View Gene Set	0.0005817	812	0.01768	3	NCI_NATURE - Internalization of ErbB1 gene set	www.pathwaycomm...
Null ErbB receptor signaling network	View Gene Set	0.0007314	841	0.01768	3	NCI_NATURE - ErbB receptor signaling network gene set	www.pathwaycomm...
Null Class I PI3K signaling events	View Gene Set	0.0008679	632	0.01794	9	NCI_NATURE - Class I PI3K signaling events gene set	www.pathwaycomm...
Null a4b1 and a4b7 Integrin signaling	View Gene Set	0.001179	28	0.02193	10	NCI_NATURE - a4b1 and a4b7 Integrin signaling gene set	www.pathwaycomm...
Null Signaling events mediated by focal adhesion kinase	View Gene Set	0.001798	660	0.02572	11	NCI_NATURE - Signaling events mediated by focal adhesion kinase gene set	www.pathwaycomm...
Null Proteogylcan syndecan-mediated signaling events	View Gene Set	0.001726	875	0.02572	11	NCI_NATURE - Proteogylcan syndecan-mediated signaling events gene set	www.pathwaycomm...
Null Paxillin-independent events mediated by a4b1 and a4b7	View Gene Set	0.001668	24	0.02572	11	NCI_NATURE - Paxillin-independent events mediated by a4b1 and a4b7 gene set	www.pathwaycomm...
Null Syndecan-1-mediated signaling events	View Gene Set	0.00245	688	0.03256	14	NCI_NATURE - Syndecan-1-mediated signaling events gene set	www.pathwaycomm...
Null Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)	View Gene Set	0.003087	677	0.03759	15	NCI_NATURE - Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) gene set	www.pathwaycomm...
Null Class I PI3K signaling events mediated by Akt	View Gene Set	0.003234	532	0.03759	15	NCI_NATURE - Class I PI3K signaling events mediated by Akt gene set	www.pathwaycomm...
Null p53 pathway	View Gene Set	0.003737	190	0.04089	17	NCI_NATURE - p53 pathway gene set	www.pathwaycomm...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null hsa-miR-106b	View Gene Set	5.241e-05	1804	0.02154	1	microRNA targets for hsa-miR-106b from miranda.targets	www.mirbase.org...
Null hsa-miR-153	View Gene Set	0.0001005	1148	0.02154	1	microRNA targets for hsa-miR-153 from miranda.targets	www.mirbase.org...
Null hsa-miR-365	View Gene Set	6.514e-05	788	0.02154	1	microRNA targets for hsa-miR-365 from miranda.targets	www.mirbase.org...
Null hsa-miR-524-5p	View Gene Set	0.0002278	2574	0.02154	1	microRNA targets for hsa-miR-524-5p from miranda.targets	www.mirbase.org...
Null hsa-miR-548d-3p	View Gene Set	0.0001648	2210	0.02154	1	microRNA targets for hsa-miR-548d-3p from miranda.targets	www.mirbase.org...
Null hsa-miR-548l	View Gene Set	0.0001953	2599	0.02154	1	microRNA targets for hsa-miR-548l from miranda.targets	www.mirbase.org...
Null hsa-miR-577	View Gene Set	0.0002546	2745	0.02154	1	microRNA targets for hsa-miR-577 from miranda.targets	www.mirbase.org...
Null hsa-miR-587	View Gene Set	0.0001672	1524	0.02154	1	microRNA targets for hsa-miR-587 from miranda.targets	www.mirbase.org...
Null hsa-miR-520d-5p	View Gene Set	0.0004015	2061	0.02721	9	microRNA targets for hsa-miR-520d-5p from miranda.targets	www.mirbase.org...
Null hsa-miR-590-3p	View Gene Set	0.0004019	3575	0.02721	9	microRNA targets for hsa-miR-590-3p from miranda.targets	www.mirbase.org...
Null hsa-miR-655	View Gene Set	0.0004522	1858	0.02783	11	microRNA targets for hsa-miR-655 from miranda.targets	www.mirbase.org...
Null hsa-miR-20b	View Gene Set	0.0006442	2122	0.03336	12	microRNA targets for hsa-miR-20b from miranda.targets	www.mirbase.org...
Null hsa-miR-376c	View Gene Set	0.0006899	1429	0.03336	12	microRNA targets for hsa-miR-376c from miranda.targets	www.mirbase.org...
Null hsa-miR-557	View Gene Set	0.0005966	1175	0.03336	12	microRNA targets for hsa-miR-557 from miranda.targets	www.mirbase.org...
Null hsa-miR-1197	View Gene Set	0.0007892	1210	0.03339	15	microRNA targets for hsa-miR-1197 from miranda.targets	www.mirbase.org...
Null hsa-miR-588	View Gene Set	0.0007579	1100	0.03339	15	microRNA targets for hsa-miR-588 from miranda.targets	www.mirbase.org...
Null hsa-miR-106a	View Gene Set	0.001087	2173	0.03589	17	microRNA targets for hsa-miR-106a from miranda.targets	www.mirbase.org...
Null hsa-miR-17	View Gene Set	0.001087	2173	0.03589	17	microRNA targets for hsa-miR-17 from miranda.targets	www.mirbase.org...
Null hsa-miR-548a-5p	View Gene Set	0.001166	2983	0.03589	17	microRNA targets for hsa-miR-548a-5p from miranda.targets	www.mirbase.org...
Null hsa-miR-548c-3p	View Gene Set	0.001152	3130	0.03589	17	microRNA targets for hsa-miR-548c-3p from miranda.targets	www.mirbase.org...
Null hsa-miR-548p	View Gene Set	0.001045	2743	0.03589	17	microRNA targets for hsa-miR-548p from miranda.targets	www.mirbase.org...
Null hsa-miR-938	View Gene Set	0.001162	580	0.03589	17	microRNA targets for hsa-miR-938 from miranda.targets	www.mirbase.org...
Null hsa-miR-19b	View Gene Set	0.001248	2017	0.03673	23	microRNA targets for hsa-miR-19b from miranda.targets	www.mirbase.org...
Null hsa-miR-342-3p	View Gene Set	0.001317	1057	0.03715	24	microRNA targets for hsa-miR-342-3p from miranda.targets	www.mirbase.org...
Null hsa-miR-548k	View Gene Set	0.001456	1874	0.03942	25	microRNA targets for hsa-miR-548k from miranda.targets	www.mirbase.org...
Null hsa-miR-768-5p	View Gene Set	0.001557	2575	0.04055	26	microRNA targets for hsa-miR-768-5p from miranda.targets	www.mirbase.org...
Null hsa-miR-1278	View Gene Set	0.00196	1219	0.04879	27	microRNA targets for hsa-miR-1278 from miranda.targets	www.mirbase.org...
Null hsa-miR-144	View Gene Set	0.002266	1767	0.04879	27	microRNA targets for hsa-miR-144 from miranda.targets	www.mirbase.org...
Null hsa-miR-410	View Gene Set	0.00245	1101	0.04879	27	microRNA targets for hsa-miR-410 from miranda.targets	www.mirbase.org...
Null hsa-miR-518a-5p	View Gene Set	0.002436	1605	0.04879	27	microRNA targets for hsa-miR-518a-5p from miranda.targets	www.mirbase.org...
Null hsa-miR-527	View Gene Set	0.002436	1605	0.04879	27	microRNA targets for hsa-miR-527 from miranda.targets	www.mirbase.org...
Null hsa-miR-548i	View Gene Set	0.002063	2860	0.04879	27	microRNA targets for hsa-miR-548i from miranda.targets	www.mirbase.org...
Null hsa-miR-559	View Gene Set	0.00228	2900	0.04879	27	microRNA targets for hsa-miR-559 from miranda.targets	www.mirbase.org...
Null hsa-miR-891b	View Gene Set	0.002349	1022	0.04879	27	microRNA targets for hsa-miR-891b from miranda.targets	www.mirbase.org...
Null hsa-miR-203	View Gene Set	0.002578	2295	0.04986	35	microRNA targets for hsa-miR-203 from miranda.targets	www.mirbase.org...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null hsa-miR-587	View Gene Set	1.761e-05	590	0.009736	1	microRNA targets for hsa-miR-587 from mirtarget2.targets	www.mirbase.org...
Null hsa-miR-545	View Gene Set	6.917e-05	600	0.01913	2	microRNA targets for hsa-miR-545 from mirtarget2.targets	www.mirbase.org...
Null hsa-miR-656	View Gene Set	0.0001787	876	0.03294	3	microRNA targets for hsa-miR-656 from mirtarget2.targets	www.mirbase.org...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null hsa-miR-124	View Gene Set	0.000211	1299	0.02574	1	microRNA targets for hsa-miR-124 from targetscan.targets	www.mirbase.org...
Null hsa-miR-506	View Gene Set	0.000211	1299	0.02574	1	microRNA targets for hsa-miR-506 from targetscan.targets	www.mirbase.org...
Null hsa-miR-144	View Gene Set	0.0003262	647	0.02653	3	microRNA targets for hsa-miR-144 from targetscan.targets	www.mirbase.org...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null miranda.mirbase.targetscan.targetsIntersection.hsa-miR-124	View Gene Set	8.877e-06	116	0.01823	1	microRNA targets for miranda.mirbase.targetscan.targetsIntersection.hsa-miR-124 from miRNAtargetIntersection	www.mirbase.org...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null miranda.mirbase.pictar.targetsUnion.hsa-miR-153	View Gene Set	5.09e-06	1840	0.007779	1	microRNA targets for miranda.mirbase.pictar.targetsUnion.hsa-miR-153 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirbase.targetscan.targetsUnion.hsa-miR-153	View Gene Set	6.723e-06	1887	0.007779	1	microRNA targets for miranda.mirbase.targetscan.targetsUnion.hsa-miR-153 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-588	View Gene Set	1.541e-05	1676	0.01189	3	microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-588 from miRNAtargetUnion	www.mirbase.org...
Null miranda.pictar.targetscan.targetsUnion.hsa-miR-153	View Gene Set	2.166e-05	1466	0.01253	4	microRNA targets for miranda.pictar.targetscan.targetsUnion.hsa-miR-153 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-153	View Gene Set	6.491e-05	1715	0.01742	5	microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-153 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-587	View Gene Set	5.252e-05	2197	0.01742	5	microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-587 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirtarget2.targetscan.targetsUnion.hsa-miR-153	View Gene Set	6.765e-05	1457	0.01742	5	microRNA targets for miranda.mirtarget2.targetscan.targetsUnion.hsa-miR-153 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirtarget2.targetscan.targetsUnion.hsa-miR-340	View Gene Set	5.637e-05	3195	0.01742	5	microRNA targets for miranda.mirtarget2.targetscan.targetsUnion.hsa-miR-340 from miRNAtargetUnion	www.mirbase.org...
Null mirtarget2.tarbase.targetscan.targetsUnion.hsa-miR-124	View Gene Set	6.777e-05	1448	0.01742	5	microRNA targets for mirtarget2.tarbase.targetscan.targetsUnion.hsa-miR-124 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirtarget2.pictar.targetsUnion.hsa-miR-106b	View Gene Set	0.0001034	2186	0.02394	10	microRNA targets for miranda.mirtarget2.pictar.targetsUnion.hsa-miR-106b from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-557	View Gene Set	0.0001209	1859	0.02491	11	microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-557 from miRNAtargetUnion	www.mirbase.org...
Null mirbase.tarbase.targetscan.targetsUnion.hsa-miR-124	View Gene Set	0.0001292	1909	0.02491	11	microRNA targets for mirbase.tarbase.targetscan.targetsUnion.hsa-miR-124 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-577	View Gene Set	0.0001529	3197	0.02721	13	microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-577 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirtarget2.targetscan.targetsUnion.hsa-miR-144	View Gene Set	0.000192	2184	0.03174	14	microRNA targets for miranda.mirtarget2.targetscan.targetsUnion.hsa-miR-144 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-548a-5p	View Gene Set	0.0002685	3746	0.03545	15	microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-548a-5p from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-559	View Gene Set	0.0002466	3456	0.03545	15	microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-559 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirtarget2.pictar.targetsUnion.hsa-miR-153	View Gene Set	0.0002862	1406	0.03545	15	microRNA targets for miranda.mirtarget2.pictar.targetsUnion.hsa-miR-153 from miRNAtargetUnion	www.mirbase.org...
Null miranda.pictar.targetscan.targetsUnion.hsa-miR-340	View Gene Set	0.0002911	2961	0.03545	15	microRNA targets for miranda.pictar.targetscan.targetsUnion.hsa-miR-340 from miRNAtargetUnion	www.mirbase.org...
Null mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-124	View Gene Set	0.0002603	1965	0.03545	15	microRNA targets for mirbase.mirtarget2.targetscan.targetsUnion.hsa-miR-124 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirbase.targetscan.targetsUnion.hsa-miR-340	View Gene Set	0.0003695	3291	0.04275	20	microRNA targets for miranda.mirbase.targetscan.targetsUnion.hsa-miR-340 from miRNAtargetUnion	www.mirbase.org...
Null miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-548d-3p	View Gene Set	0.0004321	3139	0.04761	21	microRNA targets for miranda.mirbase.mirtarget2.targetsUnion.hsa-miR-548d-3p from miRNAtargetUnion	www.mirbase.org...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null Androgen Receptor Signaling Pathway	View Gene Set	2.346e-05	437	0.0002346	1	From NetPath for Androgen Receptor Signaling Pathway	www.netpath.org...
Null TGF-beta Receptor Signaling Pathway	View Gene Set	1.681e-05	792	0.0002346	1	From NetPath for TGF-beta Receptor Signaling Pathway	www.netpath.org...
Null TNF-alpha Signaling Pathway	View Gene Set	0.0004844	728	0.003229	3	From NetPath for TNF-alpha Signaling Pathway	www.netpath.org...
Null EGFR1 Signaling Pathway	View Gene Set	0.000918	159	0.00459	4	From NetPath for EGFR1 Signaling Pathway	www.netpath.org...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null IL-2 Signaling Pathway	View Gene Set	0.0008643	291	0.008247	1	From NetPath for IL-2 Signaling Pathway	www.netpath.org...
Null TGF-beta Receptor Signaling Pathway	View Gene Set	0.0008681	739	0.008247	1	From NetPath for TGF-beta Receptor Signaling Pathway	www.netpath.org...
Null Androgen Receptor Signaling Pathway	View Gene Set	0.006561	161	0.03116	3	From NetPath for Androgen Receptor Signaling Pathway	www.netpath.org...
Null TNF-alpha Signaling Pathway	View Gene Set	0.006303	162	0.03116	3	From NetPath for TNF-alpha Signaling Pathway	www.netpath.org...
Null EGFR1 Signaling Pathway	View Gene Set	0.009353	98	0.03554	5	From NetPath for EGFR1 Signaling Pathway	www.netpath.org...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null Androgen Receptor Signaling Pathway	View Gene Set	4.622e-07	586	7.452e-06	1	From NetPath for Androgen Receptor Signaling Pathway	www.netpath.org...
Null TGF-beta Receptor Signaling Pathway	View Gene Set	7.452e-07	1296	7.452e-06	1	From NetPath for TGF-beta Receptor Signaling Pathway	www.netpath.org...
Null EGFR1 Signaling Pathway	View Gene Set	0.0001544	253	0.001029	3	From NetPath for EGFR1 Signaling Pathway	www.netpath.org...
Null TNF-alpha Signaling Pathway	View Gene Set	0.0002239	863	0.001119	4	From NetPath for TNF-alpha Signaling Pathway	www.netpath.org...
Null IL-2 Signaling Pathway	View Gene Set	0.0006442	685	0.002577	5	From NetPath for IL-2 Signaling Pathway	www.netpath.org...
Null IL-6 Signaling Pathway	View Gene Set	0.002174	105	0.007248	6	From NetPath for IL-6 Signaling Pathway	www.netpath.org...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null FSH	View Gene Set	3.082e-05	164	0.0007396	1	From NetPath for FSH	www.netpath.org...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null IL2	View Gene Set	0.001898	297	0.03607	1	From NetPath for IL2	www.netpath.org...

Gene Set Name	GeneSetDescription	Value	Gene Set Size	Corrected Value	Ranking	Description	URL
Null FSH	View Gene Set	0.0002638	263	0.006331	1	From NetPath for FSH	www.netpath.org...
Null IL2	View Gene Set	0.0007593	796	0.009112	2	From NetPath for IL2	www.netpath.org...
Null TGF_beta_Receptor	View Gene Set	0.001937	594	0.01549	3	From NetPath for TGF_beta_Receptor	www.netpath.org...
Null EGFR1	View Gene Set	0.00435	153	0.0261	4	From NetPath for EGFR1	www.netpath.org...

Results

AFA results for: tdrugda4PC3

Gene Set Collection: GO

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: Broad.c2.CGP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: Broad.c2.CP.REACTOME

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: Broad.c3.TFT

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: Broad.c4.CGN

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: Broad.c4.CM

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: Broad.c5.BP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: Broad.c5.CC

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: PMID

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: Prosite

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: Enzyme

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: pathwayCommons.nci-nature

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: miranda.targets

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: mirtarget2.targets

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: targetscan.targets

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: miRNAtargetIntersection

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: miRNAtargetUnion

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: hprdBatch.UP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: hprdBatch.DOWN

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: hprdBatch.DIFFERENT

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: hprdManual.UP

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: hprdManual.DOWN

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed

Gene Set Collection: hprdManual.DIFFERENT

Arguments: refPop=all, featureType=featureNames, colname=WilcoxABS, ranks.only=TRUE, absolute=TRUE, alternative=mixed