Test Results

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Gene Set Null TNF-alpha Signaling Pathway

featureNameslogFCAveExprtadj.P.ValBSYMBOLGENENAMEENSEMBL.HsaOMIMENTREZIDProbeName
10133-1.5779.997-43.763.161e-1225.31OPTNoptineurinENSG00000123240137760, 602432, 606657, 61343510133A_23_P1461
102051.7217.72823.455.538e-1017.55MPZL2myelin protein zero-like 2ENSG0000014957360487310205A_23_P150379
10206-0.5567.481-16.341.591e-0812.91TRIM13tripartite motif-containing 13ENSG0000020497760566110206A_23_P99360
10280-0.90518.982-19.912.418e-0915.44SIGMAR1sigma non-opioid intracellular receptor 1ENSG0000014795560197810280A_23_P146637
104683.2668.20143.993.094e-1225.38FSTfollistatinENSG00000134363136470, 18470010468A_23_P110531
107320.8468.49614.16.373e-0811.04TCFL5transcription factor-like 5 (basic helix-loop-helix)ENSG0000010119060474510732A_23_P143147
10957-1.4078.43-33.232.522e-1121.96PNRC1proline-rich nuclear receptor coactivator 1ENSG0000014627860671410957A_23_P145074
110650.86549.0718.45.012e-0914.44UBE2Cubiquitin-conjugating enzyme E2CENSG0000017506360557411065A_23_P143207
1282-1.4148.363-193.698e-0914.84COL4A1collagen, type IV, alpha 1ENSG00000187498120130, 175780, 607595, 6117731282A_23_P65240
13642.79610.1950.41.535e-1226.96CLDN4claudin 4ENSG000001891436029091364A_23_P19944
13940.964210.2813.986.923e-0810.94CRHR1corticotropin releasing hormone receptor 1ENSG00000120088, ENSG000002264601225611394A_23_P414884
14760.995512.22161.929e-0812.65CSTBcystatin B (stefin B)ENSG00000160213254800, 6011451476A_23_P154889
1525-1.1037.396-16.91.154e-0813.34CXADRcoxsackie virus and adenovirus receptorENSG000001546396026211525A_23_P57275
1822.4587.87817.747.208e-0913.96JAG1jagged 1ENSG00000101384118450, 187500, 601920182A_23_P210763
1843-3.1619.176-22.159.192e-1016.81DUSP1dual specificity phosphatase 1ENSG000001201296007141843A_23_P110712
1942-1.459.68-24.313.952e-1018EFNA1ephrin-A1ENSG000001692421911641942A_23_P254512
1958-2.6717.984-17.358.916e-0913.68EGR1early growth response 1ENSG000001207381289901958A_23_P214080
2205.02311.4490.487.653e-1532.86ALDH1A3aldehyde dehydrogenase 1 family, member A3ENSG00000184254600463220A_23_P205959
244-1.4457.583-18.594.556e-0914.56ANXA8L2annexin A8-like 2ENSG00000186807NA244A_23_P12562
253959-1.1727.895-19.233.315e-0915RALGAPA1Ral GTPase activating protein, alpha subunit 1 (catalytic)ENSG00000174373608884253959A_23_P151569
25710.72478.59314.754.166e-0811.61GAD1glutamate decarboxylase 1 (brain, 67kDa)ENSG00000128683603513, 6053632571A_23_P209578
25816-0.98848.327-14.993.571e-0811.81TNFAIP8tumor necrosis factor, alpha-induced protein 8ENSG0000014577961211125816A_23_P259116
259072.3238.98325.972.231e-1018.85TMEM158transmembrane protein 158 (gene/pseudogene)ENSG00000249992NA25907A_23_P369899
25911-0.97878.221-17.179.864e-0913.55DPCDdeleted in primary ciliary dyskinesia homolog (mouse)ENSG00000166171NA25911A_23_P52286
26574-1.0268.232-15.52.618e-0812.24AATFapoptosis antagonizing transcription factorENSG0000010827060846326574A_23_P89460
271472.4297.78213.698.508e-0810.67DENND2ADENN/MADD domain containing 2AENSG00000146966NA27147A_23_P257581
27911.28211.4413.957.116e-0810.9GNG11guanine nucleotide binding protein (G protein), gamma 11ENSG000001279206043902791A_23_P111701
28761.0212.6314.365.333e-0811.28GPX1glutathione peroxidase 1ENSG000002332761383202876A_23_P250671
2882.1037.83921.081.453e-0916.18ANK3ankyrin 3, node of Ranvier (ankyrin G)ENSG00000151150600465288A_23_P202269
289981.13911.7719.52.892e-0915.18MRPL13mitochondrial ribosomal protein L13ENSG0000017217261020028998A_23_P44974
29201.78112.0815.72.308e-0812.4CXCL2chemokine (C-X-C motif) ligand 2ENSG000000810411391102920A_23_P315364
29215.15911.1655.895.561e-1328.12CXCL3chemokine (C-X-C motif) ligand 3ENSG000001637341391112921A_23_P257219
29871.70210.4614.325.516e-0811.23GUK1guanylate kinase 1ENSG000001437741392702987A_23_P201097
301-1.34812.13-27.331.417e-1019.5ANXA1annexin A1ENSG00000135046151690301A_23_P94501
3030-0.707610.23-15.971.967e-0812.62HADHAhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunitENSG00000084754600890, 609015, 6090163030A_23_P159510
31481.57510.814.684.318e-0811.55HMGB2high-mobility group box 2ENSG000001641041639063148A_23_P155765
31510.998710.2122.637.615e-1017.09HMGN2high-mobility group nucleosomal binding domain 2ENSG000001988301639103151A_23_P97683
3383-2.5198.251-44.722.911e-1225.57ICAM1intercellular adhesion molecule 1ENSG00000090339147840, 248310, 6111623383A_23_P153320
3460-1.33710.03-23.096.309e-1017.35IFNGR2interferon gamma receptor 2 (interferon gamma transducer 1)ENSG00000159128147569, 2099503460A_23_P29034
3485-1.9348.118-20.421.941e-0915.77IGFBP2insulin-like growth factor binding protein 2, 36kDaENSG000001154571467313485A_23_P119943
353-0.722411.37-13.21.202e-0710.21APRTadenine phosphoribosyltransferaseENSG00000198931102600353A_23_P117955
35536.48910.9233.582.292e-1122.09IL1Binterleukin 1, betaENSG00000125538137215, 1477203553A_23_P79518
35693.6479.48822.348.606e-1016.92IL6interleukin 6 (interferon, beta 2)ENSG00000136244108010, 125853, 147620, 148000, 166710, 266600, 6043023569A_23_P71037
35751.477.40818.74.273e-0914.64IL7Rinterleukin 7 receptorENSG00000168685126200, 146661, 600802, 6089713575A_23_P404494
35763.26513.1818.444.909e-0914.46IL8interleukin 8ENSG000001694291469303576A_23_P81006
36244.4699.80546.082.71e-1225.92INHBAinhibin, beta AENSG000001226411472903624A_23_P122924
3678-1.0038.592-20.621.764e-0915.89ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)ENSG000001616381356203678A_23_P36554
4088-0.91218.8-16.541.412e-0813.07SMAD3SMAD family member 3ENSG000001669496031094088A_23_P48936
4124-1.1638.589-15.892.061e-0812.55MAN2A1mannosidase, alpha, class 2A, member 1ENSG000001128931545824124A_23_P18931
4637-0.998413.48-13.431.024e-0710.42MYL6myosin, light chain 6, alkali, smooth muscle and non-muscleENSG000000928416099314637A_23_P203864
4690-0.94818.579-16.21.718e-0812.8NCK1NCK adaptor protein 1ENSG000001580926005084690A_23_P255785
4714-0.914912.93-15.812.152e-0812.5NDUFB8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDaENSG000001661366021404714A_23_P24164
5052-1.5112.85-16.941.122e-0813.38PRDX1peroxiredoxin 1ENSG000001174501767635052A_23_P11995
51309-1.5157.285-28.968.494e-1120.23ARMCX1armadillo repeat containing, X-linked 1ENSG0000012694730036251309A_23_P22682
516931.4279.38322.926.789e-1017.25TRAPPC2Ltrafficking protein particle complex 2-likeENSG0000016751561097051693A_23_P206268
521-1.36212.8-13.927.259e-0810.88ATP5IATP synthase, H+ transporting, mitochondrial Fo complex, subunit EENSG00000169020601519521A_23_P125412
53281.12413.7217.617.665e-0913.87PLAUplasminogen activator, urokinaseENSG00000122861104300, 1918405328A_23_P24104
53660.73388.43214.814.006e-0811.67PMAIP1phorbol-12-myristate-13-acetate-induced protein 1ENSG000001416826049595366A_23_P207999
5683-0.97958.226-19.532.855e-0915.2PSMA2proteasome (prosome, macropain) subunit, alpha type, 2ENSG000001065881768425683A_23_P93954
5695-0.548312.5-13.78.503e-0810.67PSMB7proteasome (prosome, macropain) subunit, beta type, 7ENSG000001369306040305695A_23_P9362
57200.913510.8112.472.054e-079.493PSME1proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)ENSG000000920106006545720A_23_P151610
5723-2.22810.15-186.219e-0914.15PSPHphosphoserine phosphataseENSG000001467331724805723A_23_P251984
57430.70896.88712.631.8e-079.659PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)ENSG000000737566002625743A_23_P200345
575900.61437.60212.861.52e-079.886WDFY1WD repeat and FYVE domain containing 1ENSG00000085449NA57590A_23_P502797
576340.45337.39812.851.532e-079.876EP400E1A binding protein p400ENSG0000018349560626557634A_23_P421465
5768-1.33810.69-14.524.794e-0811.41QSOX1quiescin Q6 sulfhydryl oxidase 1ENSG000001162606031205768A_23_P12463
58062.5368.4723.585.275e-1017.61PTX3pentraxin 3, longENSG000001636616024925806A_23_P121064
5872-1.33311.13-17.398.694e-0913.71RAB13RAB13, member RAS oncogene familyENSG000001435456026725872A_23_P46365
5932-1.3129.954-12.911.469e-079.934RBBP8retinoblastoma binding protein 8ENSG000001017736041245932A_23_P252371
61460.882411.8717.67.723e-0913.86RPL22ribosomal protein L22ENSG000001162511804746146A_23_P115455
61931.08614.3315.862.089e-0812.54RPS5ribosomal protein S5ENSG000000838456036306193A_23_P208260
6277-1.01914.59-14.315.523e-0811.23S100A6S100 calcium binding protein A6ENSG000001979561141106277A_23_P201711
6605-1.1189.661-25.912.284e-1018.82SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1ENSG000000735846031116605A_23_P164387
6868-0.66347.742-13.371.062e-0710.37ADAM17ADAM metallopeptidase domain 17ENSG000001516946036396868A_23_P143120
70011.8499.69525.182.925e-1018.45PRDX2peroxiredoxin 2ENSG000001678156005387001A_23_P142045
70421.1637.23818.993.72e-0914.84TGFB2transforming growth factor, beta 2ENSG000000929691902207042A_23_P11959
71051.3158.45919.163.431e-0914.95TSPAN6tetraspanin 6ENSG000000000033001917105A_23_P171143
7126-1.5019.676-17.189.788e-0913.56TNFAIP1tumor necrosis factor, alpha-induced protein 1 (endothelial)ENSG000001090791911617126A_23_P38446
7127-2.39910.15-38.77.556e-1223.84TNFAIP2tumor necrosis factor, alpha-induced protein 2ENSG000001852156033007127A_23_P421423
7295-1.10413.75-12.581.879e-079.605TXNthioredoxinENSG000001368101877007295A_23_P60248
74241.4279.82120.481.886e-0915.81VEGFCvascular endothelial growth factor CENSG000001506306015287424A_23_P167096
78400.6997.94913.231.174e-0710.24ALMS1Alstrom syndrome 1ENSG00000116127203800, 6068447840A_23_P312174
796630.80277.38713.897.397e-0810.85HSPBAP1HSPB (heat shock 27kDa) associated protein 1ENSG0000016908760826379663A_23_P250118
79791.16713.5416.011.925e-0812.65SHFM1split hand/foot malformation (ectrodactyly) type 1ENSG00000127922183600, 6012857979A_23_P42664
79802.51210.6738.347.826e-1223.73TFPI2tissue factor pathway inhibitor 2ENSG000001058256000337980A_23_P71103
86650.58298.72914.524.78e-0811.41EIF3Feukaryotic translation initiation factor 3, subunit FENSG000001753906039148665A_23_P142774
8722-1.4017.764-17.031.065e-0813.44CTSFcathepsin FENSG000001740806035398722A_23_P24433
87671.1699.34220.272.051e-0915.67RIPK2receptor-interacting serine-threonine kinase 2ENSG000001043126034558767A_23_P252106
87741.3879.1922.886.884e-1017.23NAPGN-ethylmaleimide-sensitive factor attachment protein, gammaENSG000001342656032168774A_23_P141764
88131.66112.6420.581.796e-0915.87DPM1dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunitENSG00000000419603503, 6087998813A_23_P68472
8837-0.76668.35-13.947.142e-0810.9CFLARCASP8 and FADD-like apoptosis regulatorENSG000000034026035998837A_23_P209394
88701.25912.0814.764.131e-0811.62IER3immediate early response 3ENSG000001373316029968870A_23_P42257
8872-1.04311.94-13.778.084e-0810.74CDC123cell division cycle 123 homolog (S. cerevisiae)ENSG00000151465NA8872A_23_P150035
898010.63458.9213.191.209e-0710.2PPP1R3Fprotein phosphatase 1, regulatory (inhibitor) subunit 3FENSG00000049769NA89801A_23_P125533
9235-1.0437.405-161.936e-0812.64IL32interleukin 32ENSG000000085176060019235A_23_P15146
94239-0.839612.67-12.661.766e-079.682H2AFVH2A histone family, member VENSG00000105968NA94239A_23_P145904
970-1.8339.04-25.742.42e-1018.74CD70CD70 moleculeENSG00000125726602840970A_23_P119207
9735-0.45737.642-14.774.131e-0811.62KNTC1kinetochore associated 1ENSG000001844456073639735A_23_P136817
9925-0.86318.108-24.084.288e-1017.89ZBTB5zinc finger and BTB domain containing 5ENSG00000168795NA9925A_23_P216479
99570.67256.90513.489.868e-0810.47HS3ST1heparan sulfate (glucosamine) 3-O-sulfotransferase 1ENSG000000025876032449957A_23_P121657