Test Results

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Gene Set Broad MOOTHA_MITOCHONDRIA

featureNameslogFCAveExprtadj.P.ValBSYMBOLGENENAMEENSEMBL.HsaOMIMENTREZIDProbeName
100631.099.4216.371.513e-0812.93COX17COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)ENSG0000013849560481310063A_23_P428388
101651.027.90618.953.753e-0914.81SLC25A13solute carrier family 25, member 13 (citrin)ENSG00000004864603471, 603859, 60581410165A_23_P82336
102450.4667.45510.738.878e-077.64TIMM17Btranslocase of inner mitochondrial membrane 17 homolog B (yeast)ENSG0000012676830024910245A_23_P33886
10449-1.3858.393-13.351.048e-0710.34ACAA2acetyl-CoA acyltransferase 2ENSG0000016731560477010449A_23_P89801
104630.560910.8711.076.532e-078.024SLC30A9solute carrier family 30 (zinc transporter), member 9ENSG0000001482460460410463A_23_P30044
10671-0.46048.957-9.2393.784e-065.845DCTN6dynactin 6ENSG0000010467161296310671A_23_P43049
10873-0.66477.472-9.5412.771e-066.226ME3malic enzyme 3, NADP(+)-dependent, mitochondrialENSG0000015137660462610873A_23_P116614
108840.40468.38110.091.622e-066.897MRPS30mitochondrial ribosomal protein S30ENSG0000011299661199110884A_23_P252369
13500.789413.449.891.97e-066.655COX7Ccytochrome c oxidase subunit VIIcENSG000001271846037741350A_23_P110811
13510.691613.539.6872.4e-066.407COX8Acytochrome c oxidase subunit VIIIA (ubiquitous)ENSG000001763401238701351A_23_P52639
1355-0.62638.605-12.961.39e-079.98COX15COX15 homolog, cytochrome c oxidase assembly protein (yeast)ENSG00000014919256000, 6036461355A_23_P202374
13730.35576.62310.121.583e-066.928CPS1carbamoyl-phosphate synthase 1, mitochondrialENSG00000021826237300, 265380, 6083071373A_23_P5300
15371.0198.7899.5292.803e-066.211CYC1cytochrome c-1ENSG000001790911239801537A_23_P20980
16661.44911.128.868.351e-1120.19DECR12, 4-dienoyl CoA reductase 1, mitochondrialENSG000001043252227451666A_23_P71464
16780.87177.81615.652.321e-0812.36TIMM8Atranslocase of inner mitochondrial membrane 8 homolog A (yeast)ENSG00000126953300356, 304700, 3111501678A_23_P358417
1716-0.368410.51-9.7632.224e-066.501DGUOKdeoxyguanosine kinaseENSG00000114956251880, 6014651716A_23_P210114
1727-0.58912.69-9.6222.553e-066.327CYB5R3cytochrome b5 reductase 3ENSG00000100243250800, 6132131727A_23_P502224
17370.49018.9129.1893.98e-065.781DLATdihydrolipoamide S-acetyltransferaseENSG00000150768245348, 6087701737A_23_P203030
17770.5867.75110.321.309e-067.166DNASE2deoxyribonuclease II, lysosomalENSG000001056121263501777A_23_P119262
1854-0.595711.64-10.788.49e-077.697DUTdeoxyuridine triphosphataseENSG000001289516012661854A_23_P88484
2040.654810.1110.221.426e-067.055AK2adenylate kinase 2ENSG00000004455103020, 267500204A_23_P200404
217-3.2648.335-36.111.238e-1122.99ALDH2aldehyde dehydrogenase 2 family (mitochondrial)ENSG00000111275100650, 610251217A_23_P36745
21931.08210.4114.126.205e-0811.06FARSAphenylalanyl-tRNA synthetase, alpha subunitENSG000001791156029182193A_23_P78682
220.80678.38416.361.517e-0812.93ABCB7ATP-binding cassette, sub-family B (MDR/TAP), member 7ENSG00000131269300135, 30131022A_23_P171258
22320.962310.2318.115.803e-0914.23FDXRferredoxin reductaseENSG000001615131032702232A_23_P38154
2235-0.55658.46-10.511.093e-067.383FECHferrochelataseENSG00000066926177000, 6123862235A_23_P89789
22711.5259.97629.796.388e-1120.59FHfumarate hydrataseENSG00000091483136850, 150800, 605839, 6068122271A_23_P34733
233950.59249.0959.4243.11e-066.079LARS2leucyl-tRNA synthetase 2, mitochondrialENSG0000001137660454423395A_23_P212395
235970.597110.5810.411.199e-067.273ACOT9acyl-CoA thioesterase 9ENSG00000123130NA23597A_23_P125624
236090.55098.4112.81.57e-079.824MKRN2makorin ring finger protein 2ENSG0000007597560842623609A_23_P57807
2628-1.3557.329-12.541.928e-079.563GATMglycine amidinotransferase (L-arginine:glycine amidinotransferase)ENSG00000171766602360, 6127182628A_23_P129064
265040.74249.1929.9561.844e-066.734CNNM4cyclin M4ENSG00000158158217080, 60780526504A_23_P119923
265150.45157.97710.639.74e-077.526FXC1fracture callus 1 homolog (rat)ENSG0000013228660738826515A_23_P127851
265210.711112.479.5782.666e-066.272TIMM8Btranslocase of inner mitochondrial membrane 8 homolog B (yeast)ENSG0000015077960665926521A_23_P98382
27109-1.2458.671-10.857.958e-077.773ATP5SATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)ENSG00000125375NA27109A_23_P37296
271650.48397.22311.036.814e-077.974GLS2glutaminase 2 (liver, mitochondrial)ENSG0000013542360636527165A_23_P36416
28870.73498.08615.52.526e-0812.24GRB10growth factor receptor-bound protein 10ENSG000001060706015232887A_23_P122863
289981.22211.7720.931.497e-0916.08MRPL13mitochondrial ribosomal protein L13ENSG0000017217261020028998A_23_P44974
2908-1.7658.951-14.614.452e-0811.49NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)ENSG000001135801380402908A_23_P214059
2911.2399.17618.195.587e-0914.28SLC25A4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4ENSG00000151729103220, 157640, 192600, 609283291A_23_P133191
2921.1313.6217.687.408e-0913.92SLC25A5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5ENSG00000005022300150292A_23_P137057
29883-0.58419.16-11.454.711e-078.439CNOT7CCR4-NOT transcription complex, subunit 7ENSG0000019879160491329883A_23_P216310
29928-0.50377.759-10.031.714e-066.826TIMM22translocase of inner mitochondrial membrane 22 homolog (yeast)ENSG0000017737060725129928A_23_P55468
301.1618.49819.043.571e-0914.87ACAA1acetyl-CoA acyltransferase 1ENSG00000060971261515, 60405430A_23_P69342
3030-0.623710.23-14.076.401e-0811.01HADHAhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunitENSG00000084754600890, 609015, 6090163030A_23_P159510
3032-0.582610.73-10.061.667e-066.863HADHBhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunitENSG00000138029143450, 6090153032A_23_P79703
30330.93369.4129.3533.341e-065.99HADHhydroxyacyl-CoA dehydrogenaseENSG00000138796231530, 601609, 6099753033A_23_P167227
30521.1199.32514.494.866e-0811.38HCCSholocytochrome c synthaseENSG00000004961300056, 3098013052A_23_P257945
3100.948311.569.3843.24e-066.029ANXA7annexin A7ENSG00000138279186360310A_23_P86573
3257-0.71657.653-11.116.322e-078.067HPS1Hermansky-Pudlak syndrome 1ENSG00000107521203300, 6049823257A_23_P202361
33291.3813.7910.131.571e-066.938HSPD1heat shock 60kDa protein 1 (chaperonin)ENSG00000144381118190, 605280, 6122333329A_23_P156226
33361.16314.0519.143.393e-0914.93HSPE1heat shock 10kDa protein 1 (chaperonin 10)ENSG000001155416001413336A_23_P56922
381.04510.6820.371.929e-0915.74ACAT1acetyl-CoA acetyltransferase 1ENSG00000075239203750, 60780938A_23_P24515
3841.1087.23615.971.906e-0812.61ARG2arginase, type IIENSG00000081181107830384A_23_P128728
41281.68.04115.42.698e-0812.15MAOAmonoamine oxidase AENSG00000189221300615, 3098504128A_23_P83857
4580-0.40917.919-9.8961.957e-066.663MTX1metaxin 1ENSG000001731716006054580A_23_P137865
4594-1.0058.499-15.542.463e-0812.27MUTmethylmalonyl CoA mutaseENSG00000146085251000, 6090584594A_23_P400235
46960.893510.9314.993.46e-0811.81NDUFA3NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDaENSG000001709066038324696A_23_P208540
4698-0.4528.085-10.021.731e-066.813NDUFA5NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDaENSG000001286096016774698A_23_P60675
47101.03112.4514.315.474e-0811.22NDUFB4NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDaENSG000000655186038404710A_23_P69468
47130.82298.7059.6172.562e-066.321NDUFB7NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDaENSG000000997956038424713A_23_P50872
4714-0.962412.93-16.631.308e-0813.14NDUFB8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDaENSG000001661366021404714A_23_P24164
47180.791113.1510.738.872e-077.641NDUFC2NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDaENSG000001513666038454718A_23_P2152
47220.930312.1511.73.802e-078.702NDUFS3NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)ENSG00000213619256000, 6038464722A_23_P75398
510211.09411.659.4363.077e-066.094MRPS16mitochondrial ribosomal protein S16ENSG00000182180609204, 61049851021A_23_P97964
51312-2.1449.273-37.189.688e-1223.35SLC25A37solute carrier family 25, member 37ENSG0000014745461038751312A_23_P250833
513181.1238.95914.93.675e-0811.73MRPL35mitochondrial ribosomal protein L35ENSG0000013231361184151318A_23_P165651
515821.07610.0619.373.03e-0915.09AZIN1antizyme inhibitor 1ENSG0000015509660790951582A_23_P157435
51601.55911.530.085.919e-1120.71PDHA1pyruvate dehydrogenase (lipoamide) alpha 1ENSG00000131828300502, 308930, 3121705160A_23_P251095
51620.5189.62312.731.67e-079.749PDHBpyruvate dehydrogenase (lipoamide) betaENSG000001682911790605162A_23_P20932
51650.66317.5113.41.008e-0710.4PDK3pyruvate dehydrogenase kinase, isozyme 3ENSG000000679926025265165A_23_P250476
5180.77913.469.9131.924e-066.683ATP5G3ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)ENSG00000154518602736518A_23_P56678
521-1.33212.8-13.628.736e-0810.6ATP5IATP synthase, H+ transporting, mitochondrial Fo complex, subunit EENSG00000169020601519521A_23_P125412
5250-0.819213.57-12.681.741e-079.701SLC25A3solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3ENSG00000075415600370, 6107735250A_23_P25204
541480.822810.6611.574.258e-078.567MRPL39mitochondrial ribosomal protein L39ENSG0000015471961184554148A_23_P143446
54640.828113.3614.146.149e-0811.07PPA1pyrophosphatase (inorganic) 1ENSG000001808171790305464A_23_P161336
549480.808510.9414.933.588e-0811.77MRPL16mitochondrial ribosomal protein L16ENSG0000016690261182954948A_23_P47497
569970.81777.24111.464.674e-078.449CABC1chaperone, ABC1 activity of bc1 complex homolog (S. pombe)ENSG00000163050606980, 607426, 61201656997A_23_P85593
604881.39811.1126.211.965e-1018.96MRPS35mitochondrial ribosomal protein S35ENSG0000006179461199560488A_23_P25073
61820.75158.98410.758.702e-077.666MRPL12mitochondrial ribosomal protein L12ENSG000001830936023756182A_23_P10346
6380.87948.08111.385.008e-078.358BIKBCL2-interacting killer (apoptosis-inducing)ENSG00000100290603392638A_23_P404667
63931-1.1789.427-16.111.748e-0812.73MRPS14mitochondrial ribosomal protein S14ENSG0000012033361197863931A_23_P62731
649810.78259.81915.113.243e-0811.91MRPL34mitochondrial ribosomal protein L34ENSG0000013031261184064981A_23_P5266
66480.749.00810.41.209e-067.264SOD2superoxide dismutase 2, mitochondrialENSG00000112096147460, 6126346648A_23_P134176
665-0.65079.646-9.9821.798e-066.767BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-likeENSG00000104765605368665A_23_P134925
6687-0.869710.77-12.162.59e-079.183SPG7spastic paraplegia 7 (pure and complicated autosomal recessive)ENSG00000197912602783, 6072596687A_23_P3623
68320.75938.77712.22.506e-079.226SUPV3L1suppressor of var1, 3-like 1 (S. cerevisiae)ENSG000001565026051226832A_23_P63847
70191.57210.317.398.653e-0913.71TFAMtranscription factor A, mitochondrialENSG000001080646004387019A_23_P202258
73841.4429.86210.391.222e-067.248UQCRC1ubiquinol-cytochrome c reductase core protein IENSG000000102561913287384A_23_P132675
79780.76888.24110.699.163e-077.598MTERFmitochondrial transcription termination factorENSG000001279896023187978A_23_P408108
80340.65547.50313.459.756e-0810.44SLC25A16solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16ENSG000001229121390808034A_23_P251271
810340.80259.4759.7842.179e-066.526SLC25A32solute carrier family 25, member 32ENSG0000016493361081581034A_23_P430064
841720.59388.13410.897.668e-077.821POLR1Bpolymerase (RNA) I polypeptide B, 128kDaENSG0000012563060200084172A_23_P209987
88021.0381017.577.885e-0913.84SUCLG1succinate-CoA ligase, alpha subunitENSG00000163541245400, 6112248802A_23_P79542
89874-3.7268.667-39.326.897e-1224.03SLC25A21solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21ENSG0000018303260757189874A_23_P136504
90160.66288.58113.877.279e-0810.83SLC25A14solute carrier family 25 (mitochondrial carrier, brain), member 14ENSG000001020783002429016A_23_P135966
93610.88929.6889.6052.592e-066.306LONP1lon peptidase 1, mitochondrialENSG000001963656054909361A_23_P208469
9512-1.59511.16-25.242.763e-1018.49PMPCBpeptidase (mitochondrial processing) betaENSG000001058196031319512A_23_P134464
9804-0.737310.24-15.13.25e-0811.91TOMM20translocase of outer mitochondrial membrane 20 homolog (yeast)ENSG000001737266018489804A_23_P258544
98680.93718.10117.428.567e-0913.73TOMM70Atranslocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)ENSG000001541746060819868A_23_P144264