A Primary Xenograft Model of Small Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In-Vitro
Vincent C. Daniel, Luigi Marchionni, Jared S. Hierman, Jonathan T. Rhodes,
Wendy L. Devereux, Charles M. Rudin, Rex Yung, Marion Dorsch, Giovanni Parmigani,
Craig D. Peacock and D. Neil Watkins
Raw data, tar.gz archive
rawData.tar.gz
Additional results tables, Differentially expressed genes among laboratory models of SCLC (XG, CL, CLX)
Genes differentially expressed between XG and CL
Genes differentially expressed between CL and CLX
Genes differentially expressed between XG and CLX
Additional results tables, Functional Annotation Analysis.
Each table contains results for the three contrasts involving XG, CL, and CLX)
Gene Ontology, differentially enriched functional gene sets
KEGG, differentially enriched functional gene sets
MsigDB pathways, differentially enriched functional gene sets
Additional results tables, Differentially expressed genes using the aggregated data sets.
Analysis performed among primary tumors, normal lung, and the laboratory models (XG, CL, CLX)
Differentially expressed genes in SCLC, XG, CL and CLX compared to NORMAL
Differentially expressed genes in CL and CLX compared to SCLC and XG