Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
KEGG 03040 | View Gene Set | 1.961e-17 | 128 | 4.196e-15 | 1 | Spliceosome | www.genome.jp/d... |
KEGG 03018 | View Gene Set | 1.708e-06 | 59 | 9.447e-05 | 2 | RNA degradation | www.genome.jp/d... |
KEGG 03030 | View Gene Set | 1.144e-06 | 36 | 9.447e-05 | 2 | DNA replication | www.genome.jp/d... |
KEGG 04110 | View Gene Set | 1.766e-06 | 128 | 9.447e-05 | 2 | Cell cycle | www.genome.jp/d... |
KEGG 03050 | View Gene Set | 5.816e-05 | 48 | 0.002074 | 5 | Proteasome | www.genome.jp/d... |
KEGG 03410 | View Gene Set | 5.555e-05 | 34 | 0.002074 | 5 | Base excision repair | www.genome.jp/d... |
KEGG 04120 | View Gene Set | 0.0002473 | 139 | 0.00756 | 7 | Ubiquitin mediated proteolysis | www.genome.jp/d... |
KEGG 00240 | View Gene Set | 0.001059 | 99 | 0.02834 | 8 | Pyrimidine metabolism | www.genome.jp/d... |
KEGG 03440 | View Gene Set | 0.001413 | 28 | 0.03357 | 9 | Homologous recombination | www.genome.jp/d... |
KEGG 04623 | View Gene Set | 0.001569 | 56 | 0.03357 | 9 | Cytosolic DNA-sensing pathway | www.genome.jp/d... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
GO GO:0090304 | View Gene Set | 2.138e-59 | 3724 | 2.857e-55 | 1 | nucleic acid metabolic process | amigo.geneontol... |
GO GO:0005634 | View Gene Set | 1.549e-58 | 5198 | 1.035e-54 | 2 | nucleus | amigo.geneontol... |
GO GO:0003676 | View Gene Set | 7.145e-50 | 2979 | 3.182e-46 | 3 | nucleic acid binding | amigo.geneontol... |
GO GO:0010467 | View Gene Set | 5.577e-49 | 3806 | 1.863e-45 | 4 | gene expression | amigo.geneontol... |
GO GO:0044428 | View Gene Set | 1.294e-47 | 1938 | 3.458e-44 | 5 | nuclear part | amigo.geneontol... |
GO GO:0044260 | View Gene Set | 4.618e-46 | 5699 | 1.028e-42 | 6 | cellular macromolecule metabolic process | amigo.geneontol... |
GO GO:0003723 | View Gene Set | 8.22e-44 | 732 | 1.569e-40 | 7 | RNA binding | amigo.geneontol... |
GO GO:0031981 | View Gene Set | 3.604e-42 | 1518 | 6.018e-39 | 8 | nuclear lumen | amigo.geneontol... |
GO GO:0006139 | View Gene Set | 7.953e-42 | 4294 | 1.181e-38 | 9 | nucleobase nucleoside nucleotide and nucleic acid metabolic process | amigo.geneontol... |
GO GO:0006396 | View Gene Set | 4.849e-39 | 578 | 6.479e-36 | 10 | RNA processing | amigo.geneontol... |
GO GO:0016070 | View Gene Set | 7.917e-38 | 2596 | 9.616e-35 | 11 | RNA metabolic process | amigo.geneontol... |
GO GO:0070013 | View Gene Set | 1.594e-36 | 1845 | 1.774e-33 | 12 | intracellular organelle lumen | amigo.geneontol... |
GO GO:0043170 | View Gene Set | 4.879e-36 | 6274 | 4.656e-33 | 13 | macromolecule metabolic process | amigo.geneontol... |
GO GO:0043233 | View Gene Set | 4.604e-36 | 1881 | 4.656e-33 | 13 | organelle lumen | amigo.geneontol... |
GO GO:0031974 | View Gene Set | 9.738e-36 | 1917 | 8.674e-33 | 15 | membrane-enclosed lumen | amigo.geneontol... |
GO GO:0034641 | View Gene Set | 6.759e-34 | 4584 | 5.644e-31 | 16 | cellular nitrogen compound metabolic process | amigo.geneontol... |
GO GO:0034645 | View Gene Set | 1.885e-33 | 3529 | 1.481e-30 | 17 | cellular macromolecule biosynthetic process | amigo.geneontol... |
GO GO:0009059 | View Gene Set | 6.245e-33 | 3597 | 4.635e-30 | 18 | macromolecule biosynthetic process | amigo.geneontol... |
GO GO:0030529 | View Gene Set | 3.859e-32 | 504 | 2.713e-29 | 19 | ribonucleoprotein complex | amigo.geneontol... |
GO GO:0006807 | View Gene Set | 2.89e-30 | 4698 | 1.93e-27 | 20 | nitrogen compound metabolic process | amigo.geneontol... |
GO GO:0008380 | View Gene Set | 2.187e-28 | 300 | 1.391e-25 | 21 | RNA splicing | amigo.geneontol... |
GO GO:0005654 | View Gene Set | 3.466e-28 | 939 | 2.105e-25 | 22 | nucleoplasm | amigo.geneontol... |
GO GO:0016071 | View Gene Set | 8.193e-27 | 381 | 4.759e-24 | 23 | mRNA metabolic process | amigo.geneontol... |
GO GO:0006397 | View Gene Set | 2.008e-26 | 317 | 1.118e-23 | 24 | mRNA processing | amigo.geneontol... |
GO GO:0043227 | View Gene Set | 3.278e-25 | 8383 | 1.752e-22 | 25 | membrane-bounded organelle | amigo.geneontol... |
GO GO:0043231 | View Gene Set | 3.55e-25 | 8376 | 1.824e-22 | 26 | intracellular membrane-bounded organelle | amigo.geneontol... |
GO GO:0005730 | View Gene Set | 1.111e-23 | 734 | 5.498e-21 | 27 | nucleolus | amigo.geneontol... |
GO GO:0006350 | View Gene Set | 6.428e-21 | 2744 | 3.067e-18 | 28 | transcription | amigo.geneontol... |
GO GO:0060255 | View Gene Set | 3.04e-19 | 3411 | 1.401e-16 | 29 | regulation of macromolecule metabolic process | amigo.geneontol... |
GO GO:0010556 | View Gene Set | 3.324e-19 | 2901 | 1.48e-16 | 30 | regulation of macromolecule biosynthetic process | amigo.geneontol... |
GO GO:0044249 | View Gene Set | 5.154e-19 | 4326 | 2.221e-16 | 31 | cellular biosynthetic process | amigo.geneontol... |
GO GO:0045449 | View Gene Set | 1.775e-18 | 2647 | 7.411e-16 | 32 | regulation of transcription | amigo.geneontol... |
GO GO:0043229 | View Gene Set | 2.21e-18 | 9346 | 8.946e-16 | 33 | intracellular organelle | amigo.geneontol... |
GO GO:0043226 | View Gene Set | 2.719e-18 | 9360 | 1.069e-15 | 34 | organelle | amigo.geneontol... |
GO GO:0010468 | View Gene Set | 2.925e-18 | 2958 | 1.116e-15 | 35 | regulation of gene expression | amigo.geneontol... |
GO GO:0000375 | View Gene Set | 2.198e-17 | 106 | 8.156e-15 | 36 | RNA splicing via transesterification reactions | amigo.geneontol... |
GO GO:0009058 | View Gene Set | 2.342e-17 | 4436 | 8.456e-15 | 37 | biosynthetic process | amigo.geneontol... |
GO GO:0005681 | View Gene Set | 2.421e-17 | 135 | 8.511e-15 | 38 | spliceosomal complex | amigo.geneontol... |
GO GO:0044451 | View Gene Set | 5.005e-17 | 600 | 1.714e-14 | 39 | nucleoplasm part | amigo.geneontol... |
GO GO:0044237 | View Gene Set | 2.034e-16 | 7431 | 6.795e-14 | 40 | cellular metabolic process | amigo.geneontol... |
GO GO:0000775 | View Gene Set | 8.986e-16 | 146 | 2.928e-13 | 41 | chromosome centromeric region | amigo.geneontol... |
GO GO:0003677 | View Gene Set | 1.309e-15 | 2028 | 4.165e-13 | 42 | DNA binding | amigo.geneontol... |
GO GO:0006259 | View Gene Set | 1.426e-15 | 592 | 4.429e-13 | 43 | DNA metabolic process | amigo.geneontol... |
GO GO:0031326 | View Gene Set | 1.542e-15 | 3048 | 4.681e-13 | 44 | regulation of cellular biosynthetic process | amigo.geneontol... |
GO GO:0009889 | View Gene Set | 3.086e-15 | 3070 | 9.162e-13 | 45 | regulation of biosynthetic process | amigo.geneontol... |
GO GO:0005694 | View Gene Set | 5.117e-15 | 507 | 1.486e-12 | 46 | chromosome | amigo.geneontol... |
GO GO:0080090 | View Gene Set | 8.981e-15 | 3585 | 2.553e-12 | 47 | regulation of primary metabolic process | amigo.geneontol... |
GO GO:0000278 | View Gene Set | 1.807e-14 | 489 | 5.029e-12 | 48 | mitotic cell cycle | amigo.geneontol... |
GO GO:0000377 | View Gene Set | 1.935e-14 | 97 | 5.169e-12 | 49 | RNA splicing via transesterification reactions with bulged adenosine as nucleophile | amigo.geneontol... |
GO GO:0000398 | View Gene Set | 1.935e-14 | 97 | 5.169e-12 | 49 | nuclear mRNA splicing via spliceosome | amigo.geneontol... |
GO GO:0019219 | View Gene Set | 2.099e-14 | 3040 | 5.498e-12 | 51 | regulation of nucleobase nucleoside nucleotide and nucleic acid metabolic process | amigo.geneontol... |
GO GO:0044238 | View Gene Set | 4.628e-14 | 7629 | 1.189e-11 | 52 | primary metabolic process | amigo.geneontol... |
GO GO:0006412 | View Gene Set | 1.119e-13 | 412 | 2.822e-11 | 53 | translation | amigo.geneontol... |
GO GO:0022613 | View Gene Set | 1.269e-13 | 194 | 3.109e-11 | 54 | ribonucleoprotein complex biogenesis | amigo.geneontol... |
GO GO:0051171 | View Gene Set | 1.28e-13 | 3066 | 3.109e-11 | 54 | regulation of nitrogen compound metabolic process | amigo.geneontol... |
GO GO:0006974 | View Gene Set | 3.249e-13 | 412 | 7.751e-11 | 56 | response to DNA damage stimulus | amigo.geneontol... |
GO GO:0032991 | View Gene Set | 4.154e-13 | 3237 | 9.737e-11 | 57 | macromolecular complex | amigo.geneontol... |
GO GO:0048285 | View Gene Set | 5.324e-13 | 286 | 1.226e-10 | 58 | organelle fission | amigo.geneontol... |
GO GO:0000280 | View Gene Set | 5.952e-13 | 276 | 1.325e-10 | 59 | nuclear division | amigo.geneontol... |
GO GO:0007067 | View Gene Set | 5.952e-13 | 276 | 1.325e-10 | 59 | mitosis | amigo.geneontol... |
GO GO:0000087 | View Gene Set | 1.025e-12 | 286 | 2.245e-10 | 61 | M phase of mitotic cell cycle | amigo.geneontol... |
GO GO:0043228 | View Gene Set | 1.56e-12 | 2690 | 3.308e-10 | 62 | non-membrane-bounded organelle | amigo.geneontol... |
GO GO:0043232 | View Gene Set | 1.56e-12 | 2690 | 3.308e-10 | 62 | intracellular non-membrane-bounded organelle | amigo.geneontol... |
GO GO:0016604 | View Gene Set | 2.859e-12 | 198 | 5.967e-10 | 64 | nuclear body | amigo.geneontol... |
GO GO:0000279 | View Gene Set | 2.969e-12 | 406 | 6.103e-10 | 65 | M phase | amigo.geneontol... |
GO GO:0034470 | View Gene Set | 7.054e-12 | 193 | 1.428e-09 | 66 | ncRNA processing | amigo.geneontol... |
GO GO:0044424 | View Gene Set | 1.149e-11 | 10976 | 2.291e-09 | 67 | intracellular part | amigo.geneontol... |
GO GO:0016741 | View Gene Set | 1.664e-11 | 179 | 3.27e-09 | 68 | transferase activity transferring one-carbon groups | amigo.geneontol... |
GO GO:0005622 | View Gene Set | 2.394e-11 | 11329 | 4.636e-09 | 69 | intracellular | amigo.geneontol... |
GO GO:0044427 | View Gene Set | 2.521e-11 | 420 | 4.812e-09 | 70 | chromosomal part | amigo.geneontol... |
GO GO:0008168 | View Gene Set | 2.742e-11 | 176 | 5.159e-09 | 71 | methyltransferase activity | amigo.geneontol... |
GO GO:0006281 | View Gene Set | 3.006e-11 | 309 | 5.579e-09 | 72 | DNA repair | amigo.geneontol... |
GO GO:0008152 | View Gene Set | 3.165e-11 | 8439 | 5.793e-09 | 73 | metabolic process | amigo.geneontol... |
GO GO:0022403 | View Gene Set | 5.21e-11 | 522 | 9.406e-09 | 74 | cell cycle phase | amigo.geneontol... |
GO GO:0031323 | View Gene Set | 7.73e-11 | 3768 | 1.377e-08 | 75 | regulation of cellular metabolic process | amigo.geneontol... |
GO GO:0022402 | View Gene Set | 7.917e-11 | 676 | 1.392e-08 | 76 | cell cycle process | amigo.geneontol... |
GO GO:0000793 | View Gene Set | 1.732e-10 | 136 | 3.005e-08 | 77 | condensed chromosome | amigo.geneontol... |
GO GO:0032774 | View Gene Set | 2.655e-10 | 1953 | 4.547e-08 | 78 | RNA biosynthetic process | amigo.geneontol... |
GO GO:0006351 | View Gene Set | 2.781e-10 | 1949 | 4.684e-08 | 79 | transcription DNA-dependent | amigo.geneontol... |
GO GO:0034660 | View Gene Set | 2.805e-10 | 236 | 4.684e-08 | 79 | ncRNA metabolic process | amigo.geneontol... |
GO GO:0005840 | View Gene Set | 2.877e-10 | 198 | 4.746e-08 | 81 | ribosome | amigo.geneontol... |
GO GO:0000070 | View Gene Set | 3.078e-10 | 37 | 5.015e-08 | 82 | mitotic sister chromatid segregation | amigo.geneontol... |
GO GO:0000819 | View Gene Set | 3.394e-10 | 38 | 5.464e-08 | 83 | sister chromatid segregation | amigo.geneontol... |
GO GO:0022618 | View Gene Set | 3.826e-10 | 76 | 6.086e-08 | 84 | ribonucleoprotein complex assembly | amigo.geneontol... |
GO GO:0051276 | View Gene Set | 3.91e-10 | 548 | 6.146e-08 | 85 | chromosome organization | amigo.geneontol... |
GO GO:0007059 | View Gene Set | 1.186e-09 | 94 | 1.843e-07 | 86 | chromosome segregation | amigo.geneontol... |
GO GO:0044446 | View Gene Set | 1.33e-09 | 5019 | 2.043e-07 | 87 | intracellular organelle part | amigo.geneontol... |
GO GO:0007049 | View Gene Set | 2.016e-09 | 1006 | 3.061e-07 | 88 | cell cycle | amigo.geneontol... |
GO GO:0070647 | View Gene Set | 3.315e-09 | 356 | 4.976e-07 | 89 | protein modification by small protein conjugation or removal | amigo.geneontol... |
GO GO:0051439 | View Gene Set | 3.589e-09 | 68 | 5.328e-07 | 90 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | amigo.geneontol... |
GO GO:0000776 | View Gene Set | 4.242e-09 | 92 | 6.228e-07 | 91 | kinetochore | amigo.geneontol... |
GO GO:0051340 | View Gene Set | 5.498e-09 | 85 | 7.984e-07 | 92 | regulation of ligase activity | amigo.geneontol... |
GO GO:0006260 | View Gene Set | 5.788e-09 | 239 | 8.315e-07 | 93 | DNA replication | amigo.geneontol... |
GO GO:0051436 | View Gene Set | 6.089e-09 | 62 | 8.654e-07 | 94 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | amigo.geneontol... |
GO GO:0051351 | View Gene Set | 6.829e-09 | 74 | 9.604e-07 | 95 | positive regulation of ligase activity | amigo.geneontol... |
GO GO:0016568 | View Gene Set | 9.27e-09 | 324 | 1.29e-06 | 96 | chromatin modification | amigo.geneontol... |
GO GO:0008270 | View Gene Set | 9.834e-09 | 2009 | 1.354e-06 | 97 | zinc ion binding | amigo.geneontol... |
GO GO:0044422 | View Gene Set | 1.105e-08 | 5089 | 1.507e-06 | 98 | organelle part | amigo.geneontol... |
GO GO:0031145 | View Gene Set | 1.139e-08 | 64 | 1.537e-06 | 99 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | amigo.geneontol... |
GO GO:0051252 | View Gene Set | 2.554e-08 | 1869 | 3.412e-06 | 100 | regulation of RNA metabolic process | amigo.geneontol... |
GO GO:0051352 | View Gene Set | 2.69e-08 | 66 | 3.524e-06 | 101 | negative regulation of ligase activity | amigo.geneontol... |
GO GO:0051444 | View Gene Set | 2.69e-08 | 66 | 3.524e-06 | 101 | negative regulation of ubiquitin-protein ligase activity | amigo.geneontol... |
GO GO:0019222 | View Gene Set | 2.834e-08 | 4060 | 3.676e-06 | 103 | regulation of metabolic process | amigo.geneontol... |
GO GO:0051437 | View Gene Set | 3.047e-08 | 64 | 3.914e-06 | 104 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | amigo.geneontol... |
GO GO:0051438 | View Gene Set | 3.499e-08 | 82 | 4.452e-06 | 105 | regulation of ubiquitin-protein ligase activity | amigo.geneontol... |
GO GO:0032446 | View Gene Set | 3.578e-08 | 310 | 4.51e-06 | 106 | protein modification by small protein conjugation | amigo.geneontol... |
GO GO:0051443 | View Gene Set | 4.642e-08 | 71 | 5.797e-06 | 107 | positive regulation of ubiquitin-protein ligase activity | amigo.geneontol... |
GO GO:0003735 | View Gene Set | 5.735e-08 | 158 | 7.095e-06 | 108 | structural constituent of ribosome | amigo.geneontol... |
GO GO:0006355 | View Gene Set | 7.168e-08 | 1820 | 8.786e-06 | 109 | regulation of transcription DNA-dependent | amigo.geneontol... |
GO GO:0000779 | View Gene Set | 7.68e-08 | 79 | 9.328e-06 | 110 | condensed chromosome centromeric region | amigo.geneontol... |
GO GO:0000502 | View Gene Set | 7.779e-08 | 63 | 9.362e-06 | 111 | proteasome complex | amigo.geneontol... |
GO GO:0006399 | View Gene Set | 9.855e-08 | 118 | 1.176e-05 | 112 | tRNA metabolic process | amigo.geneontol... |
GO GO:0031397 | View Gene Set | 1.549e-07 | 78 | 1.831e-05 | 113 | negative regulation of protein ubiquitination | amigo.geneontol... |
GO GO:0042254 | View Gene Set | 1.908e-07 | 130 | 2.236e-05 | 114 | ribosome biogenesis | amigo.geneontol... |
GO GO:0007051 | View Gene Set | 2.435e-07 | 57 | 2.829e-05 | 115 | spindle organization | amigo.geneontol... |
GO GO:0008033 | View Gene Set | 2.911e-07 | 78 | 3.352e-05 | 116 | tRNA processing | amigo.geneontol... |
GO GO:0051301 | View Gene Set | 3.219e-07 | 358 | 3.675e-05 | 117 | cell division | amigo.geneontol... |
GO GO:0010605 | View Gene Set | 3.714e-07 | 827 | 4.205e-05 | 118 | negative regulation of macromolecule metabolic process | amigo.geneontol... |
GO GO:0044265 | View Gene Set | 3.866e-07 | 479 | 4.341e-05 | 119 | cellular macromolecule catabolic process | amigo.geneontol... |
GO GO:0000313 | View Gene Set | 4.035e-07 | 49 | 4.422e-05 | 120 | organellar ribosome | amigo.geneontol... |
GO GO:0000777 | View Gene Set | 4.038e-07 | 74 | 4.422e-05 | 120 | condensed chromosome kinetochore | amigo.geneontol... |
GO GO:0005761 | View Gene Set | 4.035e-07 | 49 | 4.422e-05 | 120 | mitochondrial ribosome | amigo.geneontol... |
GO GO:0000123 | View Gene Set | 4.505e-07 | 50 | 4.893e-05 | 123 | histone acetyltransferase complex | amigo.geneontol... |
GO GO:0016567 | View Gene Set | 5.102e-07 | 286 | 5.497e-05 | 124 | protein ubiquitination | amigo.geneontol... |
GO GO:0030528 | View Gene Set | 5.618e-07 | 950 | 6.005e-05 | 125 | transcription regulator activity | amigo.geneontol... |
GO GO:0016607 | View Gene Set | 7.483e-07 | 116 | 7.934e-05 | 126 | nuclear speck | amigo.geneontol... |
GO GO:0043566 | View Gene Set | 7.614e-07 | 149 | 8.01e-05 | 127 | structure-specific DNA binding | amigo.geneontol... |
GO GO:0000245 | View Gene Set | 7.724e-07 | 34 | 8.062e-05 | 128 | spliceosome assembly | amigo.geneontol... |
GO GO:0033279 | View Gene Set | 7.915e-07 | 121 | 8.197e-05 | 129 | ribosomal subunit | amigo.geneontol... |
GO GO:0005876 | View Gene Set | 1.053e-06 | 35 | 0.0001082 | 130 | spindle microtubule | amigo.geneontol... |
GO GO:0031396 | View Gene Set | 1.35e-06 | 121 | 0.0001376 | 131 | regulation of protein ubiquitination | amigo.geneontol... |
GO GO:0006511 | View Gene Set | 1.463e-06 | 296 | 0.0001481 | 132 | ubiquitin-dependent protein catabolic process | amigo.geneontol... |
GO GO:0031398 | View Gene Set | 1.499e-06 | 95 | 0.0001506 | 133 | positive regulation of protein ubiquitination | amigo.geneontol... |
GO GO:0006403 | View Gene Set | 1.552e-06 | 104 | 0.0001545 | 134 | RNA localization | amigo.geneontol... |
GO GO:0007052 | View Gene Set | 1.561e-06 | 22 | 0.0001545 | 134 | mitotic spindle organization | amigo.geneontol... |
GO GO:0043161 | View Gene Set | 1.622e-06 | 162 | 0.0001594 | 136 | proteasomal ubiquitin-dependent protein catabolic process | amigo.geneontol... |
GO GO:0010498 | View Gene Set | 1.754e-06 | 166 | 0.0001711 | 137 | proteasomal protein catabolic process | amigo.geneontol... |
GO GO:0030530 | View Gene Set | 1.767e-06 | 17 | 0.0001711 | 138 | heterogeneous nuclear ribonucleoprotein complex | amigo.geneontol... |
GO GO:0003690 | View Gene Set | 2.12e-06 | 99 | 0.0002038 | 139 | double-stranded DNA binding | amigo.geneontol... |
GO GO:0050657 | View Gene Set | 2.166e-06 | 102 | 0.0002038 | 140 | nucleic acid transport | amigo.geneontol... |
GO GO:0050658 | View Gene Set | 2.166e-06 | 102 | 0.0002038 | 140 | RNA transport | amigo.geneontol... |
GO GO:0051236 | View Gene Set | 2.166e-06 | 102 | 0.0002038 | 140 | establishment of RNA localization | amigo.geneontol... |
GO GO:0006325 | View Gene Set | 4.043e-06 | 425 | 0.0003777 | 143 | chromatin organization | amigo.geneontol... |
GO GO:0030532 | View Gene Set | 5.084e-06 | 32 | 0.0004717 | 144 | small nuclear ribonucleoprotein complex | amigo.geneontol... |
GO GO:0019941 | View Gene Set | 5.507e-06 | 302 | 0.0005039 | 145 | modification-dependent protein catabolic process | amigo.geneontol... |
GO GO:0043632 | View Gene Set | 5.507e-06 | 302 | 0.0005039 | 145 | modification-dependent macromolecule catabolic process | amigo.geneontol... |
GO GO:0000228 | View Gene Set | 5.581e-06 | 177 | 0.0005073 | 147 | nuclear chromosome | amigo.geneontol... |
GO GO:0031324 | View Gene Set | 5.873e-06 | 809 | 0.0005301 | 148 | negative regulation of cellular metabolic process | amigo.geneontol... |
GO GO:0051603 | View Gene Set | 6.165e-06 | 346 | 0.0005527 | 149 | proteolysis involved in cellular protein catabolic process | amigo.geneontol... |
GO GO:0008170 | View Gene Set | 7.102e-06 | 58 | 0.0006326 | 150 | N-methyltransferase activity | amigo.geneontol... |
GO GO:0044257 | View Gene Set | 8.169e-06 | 349 | 0.0007228 | 151 | cellular protein catabolic process | amigo.geneontol... |
GO GO:0008757 | View Gene Set | 9.713e-06 | 91 | 0.0008537 | 152 | S-adenosylmethionine-dependent methyltransferase activity | amigo.geneontol... |
GO GO:0051427 | View Gene Set | 1.021e-05 | 90 | 0.0008916 | 153 | hormone receptor binding | amigo.geneontol... |
GO GO:0051028 | View Gene Set | 1.188e-05 | 90 | 0.00103 | 154 | mRNA transport | amigo.geneontol... |
GO GO:0004386 | View Gene Set | 1.215e-05 | 144 | 0.001047 | 155 | helicase activity | amigo.geneontol... |
GO GO:0030163 | View Gene Set | 1.279e-05 | 398 | 0.001095 | 156 | protein catabolic process | amigo.geneontol... |
GO GO:0035257 | View Gene Set | 1.298e-05 | 79 | 0.001105 | 157 | nuclear hormone receptor binding | amigo.geneontol... |
GO GO:0005819 | View Gene Set | 1.436e-05 | 167 | 0.001214 | 158 | spindle | amigo.geneontol... |
GO GO:0006302 | View Gene Set | 1.493e-05 | 65 | 0.001254 | 159 | double-strand break repair | amigo.geneontol... |
GO GO:0006376 | View Gene Set | 1.552e-05 | 15 | 0.001296 | 160 | mRNA splice site selection | amigo.geneontol... |
GO GO:0009892 | View Gene Set | 1.622e-05 | 889 | 0.001346 | 161 | negative regulation of metabolic process | amigo.geneontol... |
GO GO:0010564 | View Gene Set | 1.679e-05 | 161 | 0.001385 | 162 | regulation of cell cycle process | amigo.geneontol... |
GO GO:0016569 | View Gene Set | 2.553e-05 | 165 | 0.002093 | 163 | covalent chromatin modification | amigo.geneontol... |
GO GO:0015934 | View Gene Set | 2.589e-05 | 64 | 0.002109 | 164 | large ribosomal subunit | amigo.geneontol... |
GO GO:0003713 | View Gene Set | 2.88e-05 | 215 | 0.002332 | 165 | transcription coactivator activity | amigo.geneontol... |
GO GO:0016072 | View Gene Set | 2.931e-05 | 101 | 0.002359 | 166 | rRNA metabolic process | amigo.geneontol... |
GO GO:0044267 | View Gene Set | 3.351e-05 | 2465 | 0.002681 | 167 | cellular protein metabolic process | amigo.geneontol... |
GO GO:0008276 | View Gene Set | 3.406e-05 | 59 | 0.002709 | 168 | protein methyltransferase activity | amigo.geneontol... |
GO GO:0009057 | View Gene Set | 3.457e-05 | 570 | 0.002731 | 169 | macromolecule catabolic process | amigo.geneontol... |
GO GO:0031400 | View Gene Set | 3.489e-05 | 141 | 0.002731 | 169 | negative regulation of protein modification process | amigo.geneontol... |
GO GO:0033554 | View Gene Set | 3.495e-05 | 698 | 0.002731 | 169 | cellular response to stress | amigo.geneontol... |
GO GO:0006364 | View Gene Set | 3.611e-05 | 97 | 0.002805 | 172 | rRNA processing | amigo.geneontol... |
GO GO:0016570 | View Gene Set | 4.491e-05 | 162 | 0.003469 | 173 | histone modification | amigo.geneontol... |
GO GO:0046914 | View Gene Set | 4.802e-05 | 2285 | 0.003687 | 174 | transition metal ion binding | amigo.geneontol... |
GO GO:0000314 | View Gene Set | 5.329e-05 | 18 | 0.004045 | 175 | organellar small ribosomal subunit | amigo.geneontol... |
GO GO:0005763 | View Gene Set | 5.329e-05 | 18 | 0.004045 | 175 | mitochondrial small ribosomal subunit | amigo.geneontol... |
GO GO:0003712 | View Gene Set | 5.416e-05 | 364 | 0.004088 | 177 | transcription cofactor activity | amigo.geneontol... |
GO GO:0016563 | View Gene Set | 6.205e-05 | 430 | 0.004658 | 178 | transcription activator activity | amigo.geneontol... |
GO GO:0042054 | View Gene Set | 7.354e-05 | 44 | 0.005489 | 179 | histone methyltransferase activity | amigo.geneontol... |
GO GO:0006473 | View Gene Set | 7.458e-05 | 61 | 0.005536 | 180 | protein amino acid acetylation | amigo.geneontol... |
GO GO:0007346 | View Gene Set | 8.803e-05 | 174 | 0.006498 | 181 | regulation of mitotic cell cycle | amigo.geneontol... |
GO GO:0005667 | View Gene Set | 8.926e-05 | 201 | 0.006552 | 182 | transcription factor complex | amigo.geneontol... |
GO GO:0008139 | View Gene Set | 0.0001038 | 9 | 0.00758 | 183 | nuclear localization sequence binding | amigo.geneontol... |
GO GO:0015931 | View Gene Set | 0.0001058 | 118 | 0.007653 | 184 | nucleobase nucleoside nucleotide and nucleic acid transport | amigo.geneontol... |
GO GO:0032268 | View Gene Set | 0.000106 | 576 | 0.007653 | 184 | regulation of cellular protein metabolic process | amigo.geneontol... |
GO GO:0016893 | View Gene Set | 0.0001071 | 34 | 0.007694 | 186 | endonuclease activity active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | amigo.geneontol... |
GO GO:0030518 | View Gene Set | 0.0001101 | 73 | 0.007859 | 187 | steroid hormone receptor signaling pathway | amigo.geneontol... |
GO GO:0016251 | View Gene Set | 0.0001106 | 49 | 0.007859 | 187 | general RNA polymerase II transcription factor activity | amigo.geneontol... |
GO GO:0006405 | View Gene Set | 0.0001149 | 44 | 0.008122 | 189 | RNA export from nucleus | amigo.geneontol... |
GO GO:0008134 | View Gene Set | 0.0001172 | 525 | 0.008241 | 190 | transcription factor binding | amigo.geneontol... |
GO GO:0000922 | View Gene Set | 0.0001224 | 63 | 0.008565 | 191 | spindle pole | amigo.geneontol... |
GO GO:0030522 | View Gene Set | 0.0001258 | 95 | 0.008754 | 192 | intracellular receptor mediated signaling pathway | amigo.geneontol... |
GO GO:0000387 | View Gene Set | 0.0001284 | 31 | 0.008889 | 193 | spliceosomal snRNP assembly | amigo.geneontol... |
GO GO:0016578 | View Gene Set | 0.0001314 | 15 | 0.009047 | 194 | histone deubiquitination | amigo.geneontol... |
GO GO:0030261 | View Gene Set | 0.0001468 | 27 | 0.01006 | 195 | chromosome condensation | amigo.geneontol... |
GO GO:0010629 | View Gene Set | 0.000149 | 573 | 0.01016 | 196 | negative regulation of gene expression | amigo.geneontol... |
GO GO:0003697 | View Gene Set | 0.0001775 | 58 | 0.01204 | 197 | single-stranded DNA binding | amigo.geneontol... |
GO GO:0050733 | View Gene Set | 0.0001864 | 6 | 0.01258 | 198 | RS domain binding | amigo.geneontol... |
GO GO:0050000 | View Gene Set | 0.0001937 | 17 | 0.01294 | 199 | chromosome localization | amigo.geneontol... |
GO GO:0051303 | View Gene Set | 0.0001937 | 17 | 0.01294 | 199 | establishment of chromosome localization | amigo.geneontol... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad DODD_NASOPHARYNGEAL_CARCINOMA_DN | View Gene Set | 5.44e-49 | 1253 | 1.301e-45 | 1 | Genes down-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. | www.broad.mit.e... |
Broad PUJANA_BRCA1_PCC_NETWORK | View Gene Set | 5.21e-41 | 1582 | 6.231e-38 | 2 | Genes constituting the BRCA1-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA1 [Gene ID=672] across a compendium of normal tissues. | www.broad.mit.e... |
Broad PUJANA_CHEK2_PCC_NETWORK | View Gene Set | 5.386e-39 | 744 | 4.294e-36 | 3 | Genes constituting the CHEK2-PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient PCC >= 0.4) with that of CHEK2 [Gene ID=11200]. | www.broad.mit.e... |
Broad KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP | View Gene Set | 3.755e-34 | 1180 | 2.246e-31 | 4 | Genes up-regulated in TC71 and EWS502 cells (Ewing's sarcoma) upon knockdown of the EWSR1-FLII fusion [Gene ID=2130 2314]. | www.broad.mit.e... |
Broad CAIRO_HEPATOBLASTOMA_CLASSES_UP | View Gene Set | 2.998e-32 | 577 | 1.434e-29 | 5 | Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). | www.broad.mit.e... |
Broad WONG_EMBRYONIC_STEM_CELL_CORE | View Gene Set | 8.694e-25 | 331 | 3.466e-22 | 6 | The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module. | www.broad.mit.e... |
Broad PUJANA_BRCA2_PCC_NETWORK | View Gene Set | 2.407e-24 | 410 | 8.226e-22 | 7 | Genes constituting the BRCA2-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA2 [Gene ID=675] across a compendium of normal tissues. | www.broad.mit.e... |
Broad KOBAYASHI_EGFR_SIGNALING_24HR_DN | View Gene Set | 6.539e-24 | 243 | 1.955e-21 | 8 | Genes down-regulated in H1975 cells (non-small cell lung cancer NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 24h. | www.broad.mit.e... |
Broad SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP | View Gene Set | 6.69e-23 | 143 | 1.778e-20 | 9 | Up-regulated genes whose expression correlated with histologic grade of invasive breast cancer tumors: comparison of grade 1 vs grade 3. | www.broad.mit.e... |
Broad TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C | View Gene Set | 4.586e-20 | 436 | 1.097e-17 | 10 | Genes down-regulated in HCT116 cells (colon cancer) upon expression of MIR34B or MIR34C [Gene ID=407041 407042] microRNAs. | www.broad.mit.e... |
Broad PUJANA_XPRSS_INT_NETWORK | View Gene Set | 6.724e-20 | 164 | 1.462e-17 | 11 | Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200] in a compendium of normal tissues. | www.broad.mit.e... |
Broad ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER | View Gene Set | 7.638e-20 | 138 | 1.523e-17 | 12 | The 'Cervical Cancer Proliferation Cluster' (CCPC): genes whose expression in cervical carcinoma positively correlates with that of the HPV E6 and E7 oncogenes; they are also differentially expressed according to disease outcome. | www.broad.mit.e... |
Broad MANALO_HYPOXIA_DN | View Gene Set | 2.721e-19 | 276 | 5.007e-17 | 13 | Genes down-regulated in response to both hypoxia and overexpression of an active form of HIF1A [Gene ID=3091]. | www.broad.mit.e... |
Broad NUYTTEN_EZH2_TARGETS_DN | View Gene Set | 9.618e-18 | 859 | 1.643e-15 | 14 | Genes down-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [Gene ID=2146] by RNAi. | www.broad.mit.e... |
Broad CROONQUIST_IL6_DEPRIVATION_DN | View Gene Set | 3.038e-17 | 80 | 4.541e-15 | 15 | Genes down-regulated in the ANBL-6 cell line (multiple myeloma MM) after withdrawal of IL6 [Gene ID=3569]. | www.broad.mit.e... |
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP | View Gene Set | 2.956e-17 | 184 | 4.541e-15 | 15 | Up-regulated genes in hepatocellular carcinoma (HCC) subclass G3 defined by unsupervised clustering. | www.broad.mit.e... |
Broad CROONQUIST_NRAS_SIGNALING_DN | View Gene Set | 3.667e-17 | 62 | 5.16e-15 | 17 | Genes down-regulated in ANBL-6 cell line (multiple myeloma MM) expressing a constantly active form of NRAS [Gene ID=4893] off a plasmid vector compared to those grown in the presence of IL6 [Gene ID=3569]. | www.broad.mit.e... |
Broad PUJANA_ATM_PCC_NETWORK | View Gene Set | 1.287e-16 | 1375 | 1.71e-14 | 18 | Genes constituting the ATM-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of ATM [Gene ID=472] across a compendium of normal tissues. | www.broad.mit.e... |
Broad ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN | View Gene Set | 3.538e-16 | 61 | 4.455e-14 | 19 | Genes down-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]. | www.broad.mit.e... |
Broad SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 | View Gene Set | 1.29e-15 | 435 | 1.543e-13 | 20 | Cluster 6 of method A: up-regulation of these genes in patients with non???small cell lung cancer (NSCLC) predicts poor survival outcome. | www.broad.mit.e... |
Broad BERENJENO_TRANSFORMED_BY_RHOA_UP | View Gene Set | 5.816e-15 | 485 | 6.625e-13 | 21 | Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [Gene ID=387] off plasmid vector. | www.broad.mit.e... |
Broad MUELLER_PLURINET | View Gene Set | 9.973e-15 | 294 | 1.084e-12 | 22 | Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells embryonical carcinomas and induced pluripotent cells). | www.broad.mit.e... |
Broad GARY_CD5_TARGETS_DN | View Gene Set | 8.8e-14 | 415 | 9.152e-12 | 23 | Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. | www.broad.mit.e... |
Broad BIDUS_METASTASIS_UP | View Gene Set | 1.016e-13 | 203 | 1.012e-11 | 24 | Genes up-regulated in endometroid endometrial tumors from patients with lymph node metastases compared to those without the metastases. | www.broad.mit.e... |
Broad MISSIAGLIA_REGULATED_BY_METHYLATION_DN | View Gene Set | 3.781e-13 | 96 | 3.617e-11 | 25 | Genes down-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668] a DNA hypomethylating agent similar to azacitidine [PubChem=9444]. | www.broad.mit.e... |
Broad FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | View Gene Set | 4.368e-13 | 265 | 4.019e-11 | 26 | Genes identified by method 2 as coordinately down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro. | www.broad.mit.e... |
Broad LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN | View Gene Set | 3.571e-12 | 158 | 3.164e-10 | 27 | Genes down-regulated in Wilm's tumor samples compared to fetal kidney. | www.broad.mit.e... |
Broad PUJANA_BRCA_CENTERED_NETWORK | View Gene Set | 8.285e-12 | 92 | 7.078e-10 | 28 | Genes constituting the BRCA-centered network (BCN). | www.broad.mit.e... |
Broad MARKEY_RB1_ACUTE_LOF_DN | View Gene Set | 1.189e-11 | 201 | 9.804e-10 | 29 | Genes down-regulated in adult fibroblasts with inactivated RB1 [Gene ID=5925] by Cre-lox: acute loss of function (LOF) of RB1. | www.broad.mit.e... |
Broad PAL_PRMT5_TARGETS_UP | View Gene Set | 1.51e-11 | 178 | 1.204e-09 | 30 | Genes up-regulated in NIH-3T3 cells (fibroblast) after knockdown of PRMT5 [Gene ID=10419] by RNAi. | www.broad.mit.e... |
Broad VECCHI_GASTRIC_CANCER_EARLY_UP | View Gene Set | 1.757e-11 | 408 | 1.356e-09 | 31 | Up-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. | www.broad.mit.e... |
Broad MITSIADES_RESPONSE_TO_APLIDIN_DN | View Gene Set | 3.185e-11 | 241 | 2.381e-09 | 32 | Genes down-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164] a marine-derived compound with potential anti-cancer properties. | www.broad.mit.e... |
Broad MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN | View Gene Set | 5.922e-11 | 121 | 4.292e-09 | 33 | Genes distinguishing in multiple myeloma (MM) samples with lower expression of TACI [Gene ID=23495]. | www.broad.mit.e... |
Broad PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP | View Gene Set | 6.848e-11 | 53 | 4.818e-09 | 34 | The XPRSS-Int network genes up-regulated in breast tumors from patients with germline mutations in BRCA1 [Gene ID=672] compared to those with the wild type allele. | www.broad.mit.e... |
Broad FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP | View Gene Set | 1.01e-10 | 144 | 6.902e-09 | 35 | Genes up-regulated in genomically unstable Ewing's sarcoma tumors compared to the stable ones. | www.broad.mit.e... |
Broad WEI_MYCN_TARGETS_WITH_E_BOX | View Gene Set | 1.101e-10 | 757 | 7.314e-09 | 36 | Genes whose promoters contain E-box motifs and whose expression changed in MYCN-3 cells (neuroblastoma) upon induction of MYCN [Gene ID=4613]. | www.broad.mit.e... |
Broad BENPORATH_CYCLING_GENES | View Gene Set | 1.306e-10 | 630 | 8.441e-09 | 37 | Genes showing cell-cycle stage-specific expression [PMID=12058064]. | www.broad.mit.e... |
Broad ODONNELL_TFRC_TARGETS_DN | View Gene Set | 1.481e-10 | 131 | 9.324e-09 | 38 | Genes dpwn-regulated in P493-6 cells (B lymphocyte) upon knockdown of TFRC [Gene ID=7037] by RNAi. | www.broad.mit.e... |
Broad HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | View Gene Set | 2.754e-10 | 93 | 1.689e-08 | 39 | Genes up-regulated during differentiation from large pre-BII to small pre-BII lymphocyte. | www.broad.mit.e... |
Broad ZHAN_MULTIPLE_MYELOMA_PR_UP | View Gene Set | 3.262e-10 | 43 | 1.951e-08 | 40 | Top 50 up-regulated genes in cluster PR of multiple myeloma samples characterized by increased expression of proliferation and cell cycle genes. | www.broad.mit.e... |
Broad GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP | View Gene Set | 4.63e-10 | 180 | 2.701e-08 | 41 | Genes up-regulated in quiescent CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors compared to the dividing cells from CML (chronic myeloid leukemia) patients. | www.broad.mit.e... |
Broad TIEN_INTESTINE_PROBIOTICS_24HR_UP | View Gene Set | 4.815e-10 | 537 | 2.742e-08 | 42 | Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h. | www.broad.mit.e... |
Broad WINNEPENNINCKX_MELANOMA_METASTASIS_UP | View Gene Set | 6.217e-10 | 152 | 3.459e-08 | 43 | Genes from the 254-gene classifier which were up-regulated in melanoma patients with a reported distant metastasis within 4 years. | www.broad.mit.e... |
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN | View Gene Set | 7.853e-10 | 51 | 4.269e-08 | 44 | Genes from the turquoise module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphocholine (oxPAPC). | www.broad.mit.e... |
Broad ZHANG_BREAST_CANCER_PROGENITORS_UP | View Gene Set | 1.162e-09 | 370 | 6.177e-08 | 45 | Genes changed in cancer stem cells isolated from mammary tumors compared to the non-tumorigenic cells. | www.broad.mit.e... |
Broad KANG_DOXORUBICIN_RESISTANCE_UP | View Gene Set | 1.539e-09 | 53 | 8.002e-08 | 46 | Genes differentialy expressed in gastric cancer cell lines: doxorubicin [PubChem=31703] resistant vs sensitive. | www.broad.mit.e... |
Broad SHEN_SMARCA2_TARGETS_UP | View Gene Set | 1.576e-09 | 406 | 8.023e-08 | 47 | Genes whose expression positively correlated with that of SMARCA2 [Gene ID=6595] in prostate cancer samples. | www.broad.mit.e... |
Broad REN_BOUND_BY_E2F | View Gene Set | 5.077e-09 | 47 | 2.53e-07 | 48 | Genes whose promoters were bound by E2F1 [Gene ID=1869] and E2F4 [Gene ID=1874] in the primary fibroblasts WI-38 by ChIP on chip assay. | www.broad.mit.e... |
Broad WHITEFORD_PEDIATRIC_CANCER_MARKERS | View Gene Set | 5.667e-09 | 92 | 2.766e-07 | 49 | Differentially expressed genes in a panel of xenografts representing 8 common pediatric tumors compared to the normal tissues. | www.broad.mit.e... |
Broad RUIZ_TNC_TARGETS_DN | View Gene Set | 1.314e-08 | 138 | 6.288e-07 | 50 | Genes down-regulated in T98G cells (glioblastoma) by TNC [Gene ID=3371]. | www.broad.mit.e... |
Broad KAUFFMANN_DNA_REPAIR_GENES | View Gene Set | 2.482e-08 | 205 | 1.164e-06 | 51 | Genes involved in DNA repair compiled manually by the authors. | www.broad.mit.e... |
Broad BLUM_RESPONSE_TO_SALIRASIB_DN | View Gene Set | 2.998e-08 | 332 | 1.379e-06 | 52 | Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [Gene ID=3265]. | www.broad.mit.e... |
Broad GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN | View Gene Set | 5.012e-08 | 308 | 2.262e-06 | 53 | Genes down-regulated in non-metastatic breast cancer tumors having type 1 amplification in the 20q13 region; involves ZNF217 [Gene ID=7764] locus only. | www.broad.mit.e... |
Broad LY_AGING_OLD_DN | View Gene Set | 5.947e-08 | 47 | 2.634e-06 | 54 | Genes up-regulated in fibroblasts from old individuals compared to those from young donors. | www.broad.mit.e... |
Broad SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM | View Gene Set | 1.219e-07 | 154 | 5.301e-06 | 55 | Cluster 7: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] and down-regulated by the combination of MYC and serum. | www.broad.mit.e... |
Broad ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN | View Gene Set | 1.308e-07 | 42 | 5.587e-06 | 56 | Genes down-regulated in P493-6 cells (B lymphocyte) by MYC [Gene ID=4609] and up-regulated by RNAi knockdown of TFRC [Gene ID=7037]. | www.broad.mit.e... |
Broad GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN | View Gene Set | 1.339e-07 | 86 | 5.62e-06 | 57 | Genes down-regulated in quiescent vs dividing CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors. | www.broad.mit.e... |
Broad RICKMAN_METASTASIS_UP | View Gene Set | 1.829e-07 | 316 | 7.541e-06 | 58 | Genes up-regulated in metastatic vs non-metastatic HNSCC (head and neck squamous cell carcinoma) samples. | www.broad.mit.e... |
Broad RIZ_ERYTHROID_DIFFERENTIATION | View Gene Set | 2.445e-07 | 71 | 9.913e-06 | 59 | Selected gradually up-regulated genes in the TLX1 [Gene ID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). | www.broad.mit.e... |
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | View Gene Set | 2.887e-07 | 589 | 1.143e-05 | 60 | Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. | www.broad.mit.e... |
Broad GRADE_COLON_CANCER_UP | View Gene Set | 2.914e-07 | 711 | 1.143e-05 | 60 | Up-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples. | www.broad.mit.e... |
Broad RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP | View Gene Set | 3.024e-07 | 36 | 1.148e-05 | 62 | Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors. | www.broad.mit.e... |
Broad RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_DN | View Gene Set | 3.024e-07 | 36 | 1.148e-05 | 62 | Down-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors. | www.broad.mit.e... |
Broad EGUCHI_CELL_CYCLE_RB1_TARGETS | View Gene Set | 3.374e-07 | 19 | 1.261e-05 | 64 | RB1 [Gene ID=5925] target genes involved in cell cycle regulation: genes down-regulated by doxorubicin [PubChem=31703] only in cells expressing RB1. | www.broad.mit.e... |
Broad GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN | View Gene Set | 3.604e-07 | 160 | 1.326e-05 | 65 | Genes down-regulated in metastatic breast cancer tumors having type 2 amplification in the 20q13 region; involves MYBL2 STK6 and ZNF217 [Gene ID=4605 6790 7764] | www.broad.mit.e... |
Broad MORI_LARGE_PRE_BII_LYMPHOCYTE_UP | View Gene Set | 4.262e-07 | 52 | 1.545e-05 | 66 | Up-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Large Pre-BII stage. | www.broad.mit.e... |
Broad CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP | View Gene Set | 6.626e-07 | 135 | 2.366e-05 | 67 | Top 200 marker genes up-regulated in the 'proliferation' subclass of hepatocellular carcinoma (HCC); characterized by increased proliferation high levels of serum AFP [Gene ID=174] and chromosomal instability. | www.broad.mit.e... |
Broad MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN | View Gene Set | 8.462e-07 | 42 | 2.977e-05 | 68 | Genes down-regulated in normal bone marrow plasma cells (BMPC) compared to polyclonal plasmablasts (PPC) that also distinguished multiple myeloma (MM) samples by expression of levels of TACI [Gene ID=23495]. | www.broad.mit.e... |
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN | View Gene Set | 9.644e-07 | 920 | 3.343e-05 | 69 | Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h. | www.broad.mit.e... |
Broad MILI_PSEUDOPODIA_HAPTOTAXIS_UP | View Gene Set | 1.111e-06 | 452 | 3.798e-05 | 70 | Transcripts enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin FN1 [Gene ID=2335]. | www.broad.mit.e... |
Broad HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | View Gene Set | 1.172e-06 | 241 | 3.95e-05 | 71 | Genes down-regulated in multiple myeloma (MM) cell lines treated with both decitabine [PubChem=451668] TSA [PubChem=5562]. | www.broad.mit.e... |
Broad CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP | View Gene Set | 1.697e-06 | 135 | 5.637e-05 | 72 | Genes up-regulated in CD4+ [Gene ID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]. | www.broad.mit.e... |
Broad LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER | View Gene Set | 1.906e-06 | 167 | 6.161e-05 | 73 | Overexpressed genes with amplified copy number across 27 non-small cell lung cancer (NSCLC) cell lines. | www.broad.mit.e... |
Broad MORI_IMMATURE_B_LYMPHOCYTE_DN | View Gene Set | 1.89e-06 | 52 | 6.161e-05 | 73 | Down-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the immature B stage. | www.broad.mit.e... |
Broad SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | View Gene Set | 1.936e-06 | 269 | 6.173e-05 | 75 | Genes up-regulated in nsopharyngeal carcinoma relative to the normal tissue. | www.broad.mit.e... |
Broad MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | View Gene Set | 2.249e-06 | 212 | 7.078e-05 | 76 | Genes down-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199]. | www.broad.mit.e... |
Broad MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP | View Gene Set | 3.26e-06 | 92 | 0.0001013 | 77 | Genes correlated with the early tumor onset in the Emu-myc transgenic mouse lymphoma model. | www.broad.mit.e... |
Broad LEE_EARLY_T_LYMPHOCYTE_UP | View Gene Set | 3.321e-06 | 80 | 0.0001018 | 78 | Genes up-regulated at early stages of progenitor T lymphocyte maturation compared to the late stages. | www.broad.mit.e... |
Broad DANG_MYC_TARGETS_UP | View Gene Set | 4.449e-06 | 127 | 0.0001347 | 79 | Genes up-regulated by MYC [Gene ID=4609] and whose promoters are bound by MYC according to MYC Target Gene Database. | www.broad.mit.e... |
Broad NOUZOVA_TRETINOIN_AND_H4_ACETYLATION | View Gene Set | 4.606e-06 | 124 | 0.0001377 | 80 | Genes whose CpG islands showed greatly increased histone H4 acetylation in NB4 cells (acute promyelocytic leukemia APL) upon treatment with tretinoin [PubChem=5538]. | www.broad.mit.e... |
Broad CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | View Gene Set | 5.416e-06 | 639 | 0.0001599 | 81 | Genes down-regulated in APL (acute promyeolocytic leukemia) blasts expressing PML-RARA fusion [Gene ID=5371 5914] compared to normal promyeloblasts. | www.broad.mit.e... |
Broad BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | View Gene Set | 6.27e-06 | 599 | 0.0001829 | 82 | Genes down-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress. | www.broad.mit.e... |
Broad HORIUCHI_WTAP_TARGETS_DN | View Gene Set | 7.25e-06 | 289 | 0.0002065 | 83 | Genes down-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [Gene ID=9589] by RNAi. | www.broad.mit.e... |
Broad DAZARD_RESPONSE_TO_UV_NHEK_DN | View Gene Set | 7.185e-06 | 256 | 0.0002065 | 83 | Genes down-regulated in NHEK cells (normal keratinocytes) by UV-B irradiation. | www.broad.mit.e... |
Broad KALMA_E2F1_TARGETS | View Gene Set | 8.298e-06 | 11 | 0.0002335 | 85 | DNA replication genes up-regulated in a Rat-1a cell line (fibroblast) by expression of E2F1 [Gene ID=1869]. | www.broad.mit.e... |
Broad LY_AGING_MIDDLE_DN | View Gene Set | 8.953e-06 | 15 | 0.000249 | 86 | Genes down-regulated in fibroblasts from middle-age individuals compared to those from the young donors. | www.broad.mit.e... |
Broad RIZ_ERYTHROID_DIFFERENTIATION_CCNE1 | View Gene Set | 9.266e-06 | 38 | 0.0002548 | 87 | Selected gradually up-regulated genes whose expression profile follows that of CCNE1 [Gene ID=898] in the TLX1 [Gene ID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). | www.broad.mit.e... |
Broad FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN | View Gene Set | 9.461e-06 | 43 | 0.0002572 | 88 | Genes down-regulated in MCF-7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4-hydroxytamoxifen raloxifene or ICI 182780 but not by estradiol [PubChem=44959 5035 3478439 5757]. | www.broad.mit.e... |
Broad TARTE_PLASMA_CELL_VS_PLASMABLAST_DN | View Gene Set | 9.899e-06 | 303 | 0.0002661 | 89 | Genes down-regulated in mature plasma cells compared with plasmablastic B lymphocytes. | www.broad.mit.e... |
Broad GALE_APL_WITH_FLT3_MUTATED_UP | View Gene Set | 1.002e-05 | 52 | 0.0002662 | 90 | Genes up-regulated in acute promyelocytic leukemia (APL) patients with mutated FLT3 [Gene ID=2322]. | www.broad.mit.e... |
Broad AMUNDSON_GAMMA_RADIATION_RESPONSE | View Gene Set | 1.041e-05 | 36 | 0.0002738 | 91 | Genes down-regulated across the entire panel of NCI-60 cell lines in response to gamma radiation. | www.broad.mit.e... |
Broad RAMALHO_STEMNESS_UP | View Gene Set | 1.219e-05 | 192 | 0.000317 | 92 | Genes enriched in embryonic neural and hematopoietic stem cells. | www.broad.mit.e... |
Broad BENPORATH_PROLIFERATION | View Gene Set | 1.357e-05 | 140 | 0.0003491 | 93 | Set 'Proliferation Cluster': genes defined in human breast tumor expression data. | www.broad.mit.e... |
Broad RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | View Gene Set | 1.568e-05 | 681 | 0.000399 | 94 | Genes up-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue. | www.broad.mit.e... |
Broad SONG_TARGETS_OF_IE86_CMV_PROTEIN | View Gene Set | 1.963e-05 | 49 | 0.0004942 | 95 | Cellular genes up-regulated in forskin fibroblasts by expression of CMV EI86 protein off an adenovirus vector. | www.broad.mit.e... |
Broad RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP | View Gene Set | 2.359e-05 | 220 | 0.0005879 | 96 | Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors. | www.broad.mit.e... |
Broad FINETTI_BREAST_CANCER_KINOME_RED | View Gene Set | 2.481e-05 | 15 | 0.0006055 | 97 | Genes in the red cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. | www.broad.mit.e... |
Broad FINETTI_BREAST_CANCER_BASAL_VS_LUMINAL | View Gene Set | 2.481e-05 | 15 | 0.0006055 | 97 | Protein kinases distinguishing between basal and luminal A subtypes of breast cancer. | www.broad.mit.e... |
Broad SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP | View Gene Set | 4e-05 | 16 | 0.0009666 | 99 | Genes up-regulated in MCF10A cells (breast cancer) grown at low (mesenchymal phenotype) compared to those grown at high (epithelial basal-like phenotype) confluency. | www.broad.mit.e... |
Broad FARMER_BREAST_CANCER_CLUSTER_2 | View Gene Set | 4.314e-05 | 33 | 0.001032 | 100 | Cluster 2: selected proliferation and 8q amplicon genes clustered together across breast cancer samples. | www.broad.mit.e... |
Broad BASAKI_YBX1_TARGETS_UP | View Gene Set | 5.88e-05 | 279 | 0.001381 | 101 | Genes up-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [Gene ID=4904] knockdown by RNAi. | www.broad.mit.e... |
Broad WANG_LMO4_TARGETS_DN | View Gene Set | 5.89e-05 | 327 | 0.001381 | 101 | Genes down-regulated in MCF7 cells (breast cancer) engineered to conditionally express LMO4 [Gene ID=8543] by a Tet Off system. | www.broad.mit.e... |
Broad SMID_BREAST_CANCER_LUMINAL_A_DN | View Gene Set | 6.091e-05 | 17 | 0.001415 | 103 | Genes down-regulated in the luminal A subtype of breast cancer. | www.broad.mit.e... |
Broad GRADE_COLON_AND_RECTAL_CANCER_UP | View Gene Set | 6.403e-05 | 213 | 0.001473 | 104 | Up-regulated genes in both rectal and colon carcinoma compared to normal mucosa samples. | www.broad.mit.e... |
Broad RHODES_UNDIFFERENTIATED_CANCER | View Gene Set | 6.803e-05 | 60 | 0.00155 | 105 | Genes commonly up-regulated in undifferentiated cancer relative to well-differentiated cancer based on the meta-analysis of the OncoMine gene expression database. | www.broad.mit.e... |
Broad YU_MYC_TARGETS_UP | View Gene Set | 8.043e-05 | 37 | 0.001815 | 106 | Genes up-regulated in B cell lymphoma tumors expressing an activated form of MYC [Gene ID=4609]. | www.broad.mit.e... |
Broad HELLER_HDAC_TARGETS_DN | View Gene Set | 8.416e-05 | 250 | 0.001882 | 107 | Genes down-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]. | www.broad.mit.e... |
Broad GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN | View Gene Set | 9.407e-05 | 148 | 0.002083 | 108 | Genes down-regulated in the A673 cells (Ewing sarcoma) after double knockdown of both FLI1 and DAX1 [Gene ID=2313 190] by RNAi. | www.broad.mit.e... |
Broad CHANG_CYCLING_GENES | View Gene Set | 9.819e-05 | 49 | 0.002155 | 109 | Fibroblast serum response genes showing periodic expression during the cell cycle; excluded from the core serum response signature. | www.broad.mit.e... |
Broad JISON_SICKLE_CELL_DISEASE_DN | View Gene Set | 0.0001128 | 168 | 0.002454 | 110 | Genes down-regulated in peripheral blood mononuclear cells (PBMC) from sickle cell disease patients compared to those from healthy subjects. | www.broad.mit.e... |
Broad PENG_GLUTAMINE_DEPRIVATION_DN | View Gene Set | 0.0001165 | 84 | 0.002511 | 111 | Genes down-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation. | www.broad.mit.e... |
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN | View Gene Set | 0.0001351 | 46 | 0.002885 | 112 | Cluster 6: genes down-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] in combination with serum but not affected by serum alone; they are also up-regulated by MYC alone. | www.broad.mit.e... |
Broad LIN_MELANOMA_COPY_NUMBER_UP | View Gene Set | 0.0001437 | 65 | 0.003041 | 113 | Candidate genes in significant regions of chromosomal copy number gains in a panel of melanoma samples. | www.broad.mit.e... |
Broad KIM_WT1_TARGETS_DN | View Gene Set | 0.0001501 | 431 | 0.00315 | 114 | Genes down-regulated in UB27 cells (osteosarcoma) at any time point after inducing the expression of a mutant form of WT1 [Gene ID=7490]. | www.broad.mit.e... |
Broad KAUFFMANN_DNA_REPLICATION_GENES | View Gene Set | 0.0001536 | 128 | 0.003195 | 115 | Genes involved in DNA replication compiled manually by the authors. | www.broad.mit.e... |
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP | View Gene Set | 0.0001627 | 469 | 0.003355 | 116 | Genes up-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. | www.broad.mit.e... |
Broad FURUKAWA_DUSP6_TARGETS_PCI35_DN | View Gene Set | 0.0001731 | 66 | 0.003539 | 117 | Genes down-regulated in PCI-35 cells (pancreatic cancer lack endogenous DUSP6 [Gene ID=1848]) upon expression of DUSP6 off an adenoviral vector. | www.broad.mit.e... |
Broad NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | View Gene Set | 0.0001913 | 263 | 0.003877 | 118 | Up-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone. | www.broad.mit.e... |
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 | View Gene Set | 0.0001951 | 158 | 0.003922 | 119 | Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 13. | www.broad.mit.e... |
Broad SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN | View Gene Set | 0.0002104 | 22 | 0.004194 | 120 | Cell cycle genes changed in H1299 cells (lung cancer) after overexpression of either P53 [Gene ID=7157] or P73 [Gene ID=7161]. | www.broad.mit.e... |
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN | View Gene Set | 0.0002507 | 832 | 0.004957 | 121 | Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. | www.broad.mit.e... |
Broad AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP | View Gene Set | 0.0002804 | 288 | 0.005498 | 122 | Up-regulated genes whose expression correlates with copy number gains in pancreatic adenocarcinoma cell lines and primary tumor specimens. | www.broad.mit.e... |
Broad MATTIOLI_MGUS_VS_PCL | View Gene Set | 0.0002844 | 109 | 0.005531 | 123 | Genes changed in MGUS (monoclonal gammopathy of undetermined significance) compared to PCL (plasma cell leukemia) samples. | www.broad.mit.e... |
Broad CHANG_CORE_SERUM_RESPONSE_UP | View Gene Set | 0.0003115 | 66 | 0.006009 | 124 | Up-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group. | www.broad.mit.e... |
Broad LE_EGR2_TARGETS_UP | View Gene Set | 0.0003283 | 100 | 0.006282 | 125 | Genes up-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [Gene ID=1959]. | www.broad.mit.e... |
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP | View Gene Set | 0.0003661 | 44 | 0.00695 | 126 | Up-regulated genes in hepatocellular carcinoma (HCC) subclass G123 defined by unsupervised clustering. | www.broad.mit.e... |
Broad KIM_WT1_TARGETS_12HR_DN | View Gene Set | 0.0003722 | 200 | 0.007011 | 127 | Genes down-regulated in UB27 cells (osteosarcoma) at 12 hr after inducing the expression of a mutated form of WT1 [Gene ID=7490]. | www.broad.mit.e... |
Broad GENTILE_UV_RESPONSE_CLUSTER_D4 | View Gene Set | 0.00038 | 49 | 0.007101 | 128 | Cluster d4: genes progressively down-regulated in WS1 cells (fibroblast) through 12 h after irradiation with high dose UV-C. | www.broad.mit.e... |
Broad WONG_PROTEASOME_GENE_MODULE | View Gene Set | 0.0004084 | 46 | 0.007573 | 129 | Genes that comprise the proteasome gene module | www.broad.mit.e... |
Broad MEINHOLD_OVARIAN_CANCER_LOW_GRADE_DN | View Gene Set | 0.0004144 | 18 | 0.007625 | 130 | Genes down-regulated in low grade (LMP and G1) serous ovarian carcinomas vs the higher grade invasive tumors (G2 and G3). | www.broad.mit.e... |
Broad ONDER_CDH1_TARGETS_1_DN | View Gene Set | 0.0004648 | 161 | 0.008422 | 131 | Genes down-regulated in HMLE cells (mmortalized nontransformed mammary epithelial) by expression of a dominant-negative form of E-cadhedrin (CDH1) [Gene ID=999]. | www.broad.mit.e... |
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 | View Gene Set | 0.0004624 | 165 | 0.008422 | 131 | Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 17. | www.broad.mit.e... |
Broad MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP | View Gene Set | 0.0004863 | 10 | 0.008747 | 133 | Up-regulated genes predicting poor survival of patients with thyroid carcinoma. | www.broad.mit.e... |
Broad STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN | View Gene Set | 0.0004922 | 437 | 0.008786 | 134 | Genes down-regulated in prefrontal cortex (PFC) of mice carrying a hemizygotic microdeletion in the 22q11.2 region. | www.broad.mit.e... |
Broad SEMBA_FHIT_TARGETS_DN | View Gene Set | 0.0005093 | 10 | 0.009025 | 135 | Genes down-regulated in H1299 cells (non-small cell lung cancer NSCLC) expressing the Y144F mutant form of FHIT [Gene ID=2272]. | www.broad.mit.e... |
Broad ENK_UV_RESPONSE_KERATINOCYTE_DN | View Gene Set | 0.0005219 | 475 | 0.00918 | 136 | Genes down-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation. | www.broad.mit.e... |
Broad RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN | View Gene Set | 0.0005304 | 351 | 0.009194 | 137 | Genes down-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids. | www.broad.mit.e... |
Broad GEORGES_CELL_CYCLE_MIR192_TARGETS | View Gene Set | 0.000528 | 59 | 0.009194 | 137 | Experimentally validated direct targets of MIR192 [Gene ID=406967] microRNA; MIR192 caused cell cycle arrest in HCT116 cells (colon cancer). | www.broad.mit.e... |
Broad FUJII_YBX1_TARGETS_DN | View Gene Set | 0.0005939 | 139 | 0.01022 | 139 | Genes down-regulated in MCF-7 cells (breast cancer) after knockdown of YBX1 [Gene ID=4904] by RNAi. | www.broad.mit.e... |
Broad RHODES_CANCER_META_SIGNATURE | View Gene Set | 0.0006006 | 54 | 0.01026 | 140 | Genes commonly up-regulated in cancer relative to normal tissue according to the meta-analysis of the OncoMine gene expression database. | www.broad.mit.e... |
Broad WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 | View Gene Set | 0.0006571 | 36 | 0.01115 | 141 | Genes downstream of both CDKN1A and TP53 [Gene ID=1026 7157] in 2774qw1 cells (ovarian cancer). | www.broad.mit.e... |
Broad DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | View Gene Set | 0.0006881 | 1353 | 0.01159 | 142 | Genes up-regulated in CD34+ [Gene ID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients compared to those from normal donors. | www.broad.mit.e... |
Broad LINDGREN_BLADDER_CANCER_CLUSTER_3_UP | View Gene Set | 0.0007054 | 314 | 0.0118 | 143 | Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors. | www.broad.mit.e... |
Broad DAZARD_UV_RESPONSE_CLUSTER_G6 | View Gene Set | 0.0007235 | 122 | 0.01202 | 144 | Cluster G6: genes increasingly down-regulated in NHEK cells (normal keratinocyte) after UV-B irradiation. | www.broad.mit.e... |
Broad WELCSH_BRCA1_TARGETS_1_DN | View Gene Set | 0.0007486 | 124 | 0.01235 | 145 | Upregulated by induction of exogenous BRCA1 in EcR-293 cells | www.broad.mit.e... |
Broad LEE_LIVER_CANCER_SURVIVAL_DN | View Gene Set | 0.0007694 | 123 | 0.01261 | 146 | Genes highly expressed in hepatocellular carcinoma with poor survival. | www.broad.mit.e... |
Broad GEORGES_TARGETS_OF_MIR192_AND_MIR215 | View Gene Set | 0.0007831 | 809 | 0.01274 | 147 | Genes down-regulated in HCT116 cells (colon cancer) by expression of MIR192 or MIR215 [Gene ID=406967 406997] at 24 h. | www.broad.mit.e... |
Broad GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP | View Gene Set | 0.0007961 | 26 | 0.01287 | 148 | Genes from the magenta module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC). | www.broad.mit.e... |
Broad COLDREN_GEFITINIB_RESISTANCE_UP | View Gene Set | 0.0008183 | 74 | 0.01314 | 149 | Genes up-regulated in NSCLC (non-small cell lung carcinoma) cell lines resistant to gefitinib [PubChem=123631] compared to the sensitive ones. | www.broad.mit.e... |
Broad MOOTHA_MITOCHONDRIA | View Gene Set | 0.0008691 | 433 | 0.01386 | 150 | Mitochondrial genes | www.broad.mit.e... |
Broad SLEBOS_HEAD_AND_NECK_CANCER_WITH_HPV_UP | View Gene Set | 0.000988 | 72 | 0.01565 | 151 | Genes up-regulated in head and neck squamous cell carcinoma (HNSCC) samples positive for HPV compared to the HPV-negative tumors. | www.broad.mit.e... |
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | View Gene Set | 0.001029 | 418 | 0.0162 | 152 | Common down-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [Gene ID=2071] after UVC irradiation. | www.broad.mit.e... |
Broad VERNELL_RETINOBLASTOMA_PATHWAY_UP | View Gene Set | 0.001052 | 39 | 0.01645 | 153 | Cluster 1: genes up-regulated by RB1 [Gene ID=5925] CDNK2A [Gene ID=1029] and one of the E2Fs (E2F1 E2F2 or E2F3 [Gene ID=1869 1870 1871]). | www.broad.mit.e... |
Broad PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP | View Gene Set | 0.001121 | 175 | 0.01737 | 154 | Up-regulated genes in head and neck cancer compared to cervical carcinoma samples. | www.broad.mit.e... |
Broad IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR | View Gene Set | 0.001126 | 100 | 0.01737 | 154 | Genes in the expression cluster 'Early Progenitors Shared': up-regulated in hematopoietic progenitors from adult bone marrow and from fetal liver. | www.broad.mit.e... |
Broad ZHAN_VARIABLE_EARLY_DIFFERENTIATION_GENES_DN | View Gene Set | 0.001179 | 26 | 0.01808 | 156 | The vEDG set: most variable early differentiation genes (EDG) with similar expression patterns in tonsil B lymphocytes (TBC) and multiple myeloma (MM) cells compared to the plasma cells from tonsil (TPC) and bone marrow (BPC). | www.broad.mit.e... |
Broad PUJANA_BREAST_CANCER_LIT_INT_NETWORK | View Gene Set | 0.001192 | 100 | 0.01817 | 157 | Genes constituting the LIT-Int network of proteins interacting with breast cancer reference proteins BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200]; the interactions were manually curated from the literature. | www.broad.mit.e... |
Broad MOOTHA_VOXPHOS | View Gene Set | 0.001619 | 82 | 0.02451 | 158 | Genes involved in oxidative phosphorylation; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. | www.broad.mit.e... |
Broad NADERI_BREAST_CANCER_PROGNOSIS_UP | View Gene Set | 0.001746 | 37 | 0.02627 | 159 | Up-regulated genes in the breast cancer prognostic signature of 70 genes that significantly correlated with survival. | www.broad.mit.e... |
Broad GENTILE_UV_RESPONSE_CLUSTER_D5 | View Gene Set | 0.001783 | 28 | 0.02665 | 160 | Cluster d5: genes progressively down-regulated in WS1 cells (fibroblast) through 18 h after irradiation with high dose UV-C. | www.broad.mit.e... |
Broad MARKS_HDAC_TARGETS_DN | View Gene Set | 0.001804 | 14 | 0.0268 | 161 | Genes whose transcription is altered by histone deacetylase inhibitors. | www.broad.mit.e... |
Broad SHEPARD_BMYB_TARGETS | View Gene Set | 0.002006 | 60 | 0.02962 | 162 | Human orthologs of BMYB [Gene ID=4605] target genes in zebra fish identified as commonly changed in the BMYB loss of function mutant crb ('crush and burn') and after knockdown of BMYB by morpholino. | www.broad.mit.e... |
Broad NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | View Gene Set | 0.00215 | 87 | 0.03155 | 163 | Top 100 probe sets contrubuting to the positive side of the 2nd principal component; associated with adipocytic differentiation. | www.broad.mit.e... |
Broad SHEPARD_CRUSH_AND_BURN_MUTANT_DN | View Gene Set | 0.00227 | 147 | 0.03311 | 164 | Human orthologs of genes down-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [Gene ID=4605]. | www.broad.mit.e... |
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | View Gene Set | 0.002474 | 825 | 0.03565 | 165 | Genes down-regulated in fibroblasts expressing mutant forms of ERCC3 [Gene ID=2071] after UV irradiation. | www.broad.mit.e... |
Broad VANTVEER_BREAST_CANCER_METASTASIS_DN | View Gene Set | 0.002463 | 104 | 0.03565 | 165 | Genes whose expression is significantly and negatively correlated with poor breast cancer clinical outcome (defined as developing distant metastases in less than 5 years). | www.broad.mit.e... |
Broad SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY | View Gene Set | 0.002665 | 31 | 0.03817 | 167 | Cluster 3: genes strongly up-regulated in B493-6 cells (B lymphocytes) by a combination of MYC [Gene ID=4609] and serum but not by each of them alone. | www.broad.mit.e... |
Broad SU_TESTIS | View Gene Set | 0.002719 | 75 | 0.03872 | 168 | Genes up-regulated specifically in human testis tissue. | www.broad.mit.e... |
Broad ZHANG_RESPONSE_TO_CANTHARIDIN_DN | View Gene Set | 0.002754 | 60 | 0.03898 | 169 | Genes down-regulated in HL-60 cells (promyeloid leukemia) by cantharidin [PubChem=6708701]. | www.broad.mit.e... |
Broad LY_AGING_PREMATURE_DN | View Gene Set | 0.002939 | 24 | 0.04135 | 170 | Genes down-regulated in fibroblasts from patients with Hutchinson-Gilford progeria (premature aging) compared to those from normal young individuals. | www.broad.mit.e... |
Broad BENPORATH_ES_1 | View Gene Set | 0.003237 | 367 | 0.04527 | 171 | Set 'ES exp1': genes overexpressed in human embryonic stem cells according to 5 or more out of 20 profiling studies. | www.broad.mit.e... |
Broad BROWNE_HCMV_INFECTION_14HR_DN | View Gene Set | 0.003309 | 289 | 0.04602 | 172 | Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not down-regulated at the previous time point 12 h. | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad BIOCARTA_RANMS_PATHWAY | View Gene Set | 2.682e-05 | 10 | 0.005821 | 1 | Role of Ran in mitotic spindle regulation | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad KEGG_SPLICEOSOME | View Gene Set | 1.119e-13 | 118 | 2.081e-11 | 1 | Spliceosome | www.broad.mit.e... |
Broad KEGG_RNA_DEGRADATION | View Gene Set | 1.708e-06 | 59 | 8.211e-05 | 2 | RNA degradation | www.broad.mit.e... |
Broad KEGG_DNA_REPLICATION | View Gene Set | 1.144e-06 | 36 | 8.211e-05 | 2 | DNA replication | www.broad.mit.e... |
Broad KEGG_CELL_CYCLE | View Gene Set | 1.766e-06 | 128 | 8.211e-05 | 2 | Cell cycle | www.broad.mit.e... |
Broad KEGG_PROTEASOME | View Gene Set | 5.816e-05 | 48 | 0.001803 | 5 | Proteasome | www.broad.mit.e... |
Broad KEGG_BASE_EXCISION_REPAIR | View Gene Set | 5.555e-05 | 35 | 0.001803 | 5 | Base excision repair | www.broad.mit.e... |
Broad KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS | View Gene Set | 0.000365 | 138 | 0.009699 | 7 | Ubiquitin mediated proteolysis | www.broad.mit.e... |
Broad KEGG_PYRIMIDINE_METABOLISM | View Gene Set | 0.00158 | 98 | 0.02939 | 8 | Pyrimidine metabolism | www.broad.mit.e... |
Broad KEGG_HOMOLOGOUS_RECOMBINATION | View Gene Set | 0.001413 | 28 | 0.02939 | 8 | Homologous recombination | www.broad.mit.e... |
Broad KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY | View Gene Set | 0.001569 | 56 | 0.02939 | 8 | Cytosolic DNA-sensing pathway | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad REACTOME_MITOTIC_M_M_G1_PHASES | View Gene Set | 5.019e-15 | 157 | 2.158e-12 | 1 | Genes involved in Mitotic M-M/G1 phases | www.broad.mit.e... |
Broad REACTOME_CELL_CYCLE_MITOTIC | View Gene Set | 5.824e-14 | 306 | 1.252e-11 | 2 | Genes involved in Cell Cycle Mitotic | www.broad.mit.e... |
Broad REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA | View Gene Set | 7.878e-13 | 128 | 1.129e-10 | 3 | Genes involved in Processing of Capped Intron-Containing Pre-mRNA | www.broad.mit.e... |
Broad REACTOME_GENE_EXPRESSION | View Gene Set | 3.585e-12 | 415 | 3.837e-10 | 4 | Genes involved in Gene Expression | www.broad.mit.e... |
Broad REACTOME_MRNA_SPLICING | View Gene Set | 4.462e-12 | 97 | 3.837e-10 | 4 | Genes involved in mRNA Splicing | www.broad.mit.e... |
Broad REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS | View Gene Set | 3.221e-11 | 124 | 2.308e-09 | 6 | Genes involved in Elongation and Processing of Capped Transcripts | www.broad.mit.e... |
Broad REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT | View Gene Set | 1.338e-10 | 142 | 8.219e-09 | 7 | Genes involved in Formation and Maturation of mRNA Transcript | www.broad.mit.e... |
Broad REACTOME_METABOLISM_OF_RNA | View Gene Set | 3.166e-10 | 95 | 1.702e-08 | 8 | Genes involved in Metabolism of RNA | www.broad.mit.e... |
Broad REACTOME_CELL_CYCLE_CHECKPOINTS | View Gene Set | 5.955e-10 | 110 | 2.845e-08 | 9 | Genes involved in Cell Cycle Checkpoints | www.broad.mit.e... |
Broad REACTOME_MITOTIC_PROMETAPHASE | View Gene Set | 8.316e-09 | 92 | 3.576e-07 | 10 | Genes involved in Mitotic Prometaphase | www.broad.mit.e... |
Broad REACTOME_REGULATION_OF_APC_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE | View Gene Set | 4.225e-08 | 71 | 1.651e-06 | 11 | Genes involved in Regulation of APC/C activators between G1/S and early anaphase | www.broad.mit.e... |
Broad REACTOME_CDC20_PHOSPHO_APC_MEDIATED_DEGRADATION_OF_CYCLIN_A | View Gene Set | 1.162e-07 | 63 | 4.164e-06 | 12 | Genes involved in Cdc20:Phospho-APC/C mediated degradation of Cyclin A | www.broad.mit.e... |
Broad REACTOME_DNA_REPLICATION_PRE_INITIATION | View Gene Set | 1.321e-07 | 76 | 4.369e-06 | 13 | Genes involved in DNA Replication Pre-Initiation | www.broad.mit.e... |
Broad REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC | View Gene Set | 7.424e-07 | 57 | 2.013e-05 | 14 | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C | www.broad.mit.e... |
Broad REACTOME_G1_S_TRANSITION | View Gene Set | 6.731e-07 | 102 | 2.013e-05 | 14 | Genes involved in G1/S Transition | www.broad.mit.e... |
Broad REACTOME_M_G1_TRANSITION | View Gene Set | 7.49e-07 | 61 | 2.013e-05 | 14 | Genes involved in M/G1 Transition | www.broad.mit.e... |
Broad REACTOME_METABOLISM_OF_MRNA | View Gene Set | 1.72e-06 | 45 | 4.351e-05 | 17 | Genes involved in Metabolism of mRNA | www.broad.mit.e... |
Broad REACTOME_SYNTHESIS_OF_DNA | View Gene Set | 4.164e-06 | 89 | 9.595e-05 | 18 | Genes involved in Synthesis of DNA | www.broad.mit.e... |
Broad REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | View Gene Set | 4.24e-06 | 47 | 9.595e-05 | 18 | Genes involved in Vif-mediated degradation of APOBEC3G | www.broad.mit.e... |
Broad REACTOME_S_PHASE | View Gene Set | 5.124e-06 | 103 | 0.0001102 | 20 | Genes involved in S Phase | www.broad.mit.e... |
Broad REACTOME_DEADENYLATION_OF_MRNA | View Gene Set | 5.586e-06 | 21 | 0.0001144 | 21 | Genes involved in Deadenylation of mRNA | www.broad.mit.e... |
Broad REACTOME_STABILIZATION_OF_P53 | View Gene Set | 7.42e-06 | 46 | 0.000145 | 22 | Genes involved in Stabilization of p53 | www.broad.mit.e... |
Broad REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE | View Gene Set | 1.078e-05 | 43 | 0.0002015 | 23 | Genes involved in p53-Independent DNA Damage Response | www.broad.mit.e... |
Broad REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | View Gene Set | 1.33e-05 | 48 | 0.0002384 | 24 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 | www.broad.mit.e... |
Broad REACTOME_SNRNP_ASSEMBLY | View Gene Set | 1.921e-05 | 50 | 0.0003303 | 25 | Genes involved in snRNP Assembly | www.broad.mit.e... |
Broad REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | View Gene Set | 2.762e-05 | 120 | 0.0004568 | 26 | Genes involved in Host Interactions of HIV factors | www.broad.mit.e... |
Broad REACTOME_ORC1_REMOVAL_FROM_CHROMATIN | View Gene Set | 4.63e-05 | 63 | 0.0007374 | 27 | Genes involved in Orc1 removal from chromatin | www.broad.mit.e... |
Broad REACTOME_MRNA_3_END_PROCESSING | View Gene Set | 4.914e-05 | 25 | 0.0007546 | 28 | Genes involved in mRNA 3-end processing | www.broad.mit.e... |
Broad REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRON_CONTAINING_TRANSCRIPT | View Gene Set | 6.969e-05 | 42 | 0.001033 | 29 | Genes involved in Transport of Mature mRNA derived from an Intron-Containing Transcript | www.broad.mit.e... |
Broad REACTOME_G2_M_CHECKPOINTS | View Gene Set | 9.979e-05 | 43 | 0.00143 | 30 | Genes involved in G2/M Checkpoints | www.broad.mit.e... |
Broad REACTOME_HIV_INFECTION | View Gene Set | 0.000129 | 183 | 0.00179 | 31 | Genes involved in HIV Infection | www.broad.mit.e... |
Broad REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX | View Gene Set | 0.0001491 | 52 | 0.002003 | 32 | Genes involved in CDT1 association with the CDC6:ORC:origin complex | www.broad.mit.e... |
Broad REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE | View Gene Set | 0.0002153 | 47 | 0.002723 | 33 | Genes involved in Regulation of ornithine decarboxylase (ODC) | www.broad.mit.e... |
Broad REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21 | View Gene Set | 0.0002137 | 52 | 0.002723 | 33 | Genes involved in SCF(Skp2)-mediated degradation of p2721 | www.broad.mit.e... |
Broad REACTOME_DNA_STRAND_ELONGATION | View Gene Set | 0.0003505 | 31 | 0.004187 | 35 | Genes involved in DNA strand elongation | www.broad.mit.e... |
Broad REACTOME_INACTIVATION_OF_APC_VIA_DIRECT_INHIBITION_OF_THE_APCOMPLEX | View Gene Set | 0.0003451 | 18 | 0.004187 | 35 | Genes involved in Inactivation of APC/C via direct inhibition of the APC/C complex | www.broad.mit.e... |
Broad REACTOME_METABOLISM_OF_PROTEINS | View Gene Set | 0.0004339 | 215 | 0.005043 | 37 | Genes involved in Metabolism of proteins | www.broad.mit.e... |
Broad REACTOME_TRNA_AMINOACYLATION | View Gene Set | 0.0004508 | 40 | 0.005101 | 38 | Genes involved in tRNA Aminoacylation | www.broad.mit.e... |
Broad REACTOME_INFLUENZA_LIFE_CYCLE | View Gene Set | 0.0004971 | 137 | 0.005481 | 39 | Genes involved in Influenza Life Cycle | www.broad.mit.e... |
Broad REACTOME_REV_MEDIATED_NUCLEAR_EXPORT_OF_HIV1_RNA | View Gene Set | 0.0005614 | 31 | 0.005995 | 40 | Genes involved in Rev-mediated nuclear export of HIV-1 RNA | www.broad.mit.e... |
Broad REACTOME_TRANSLATION | View Gene Set | 0.0005716 | 120 | 0.005995 | 40 | Genes involved in Translation | www.broad.mit.e... |
Broad REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT | View Gene Set | 0.000597 | 106 | 0.006007 | 42 | Genes involved in GTP hydrolysis and joining of the 60S ribosomal subunit | www.broad.mit.e... |
Broad REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | View Gene Set | 0.0006007 | 29 | 0.006007 | 42 | Genes involved in Association of TriC/CCT with target proteins during biosynthesis | www.broad.mit.e... |
Broad REACTOME_DNA_REPAIR | View Gene Set | 0.0006648 | 102 | 0.006352 | 44 | Genes involved in DNA Repair | www.broad.mit.e... |
Broad REACTOME_PHOSPHORYLATION_OF_THE_APC | View Gene Set | 0.000652 | 17 | 0.006352 | 44 | Genes involved in Phosphorylation of the APC/C | www.broad.mit.e... |
Broad REACTOME_DOUBLE_STRAND_BREAK_REPAIR | View Gene Set | 0.0008313 | 21 | 0.007701 | 46 | Genes involved in Double-Strand Break Repair | www.broad.mit.e... |
Broad REACTOME_SIGNALING_BY_WNT | View Gene Set | 0.0008418 | 58 | 0.007701 | 46 | Genes involved in Signaling by Wnt | www.broad.mit.e... |
Broad REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN | View Gene Set | 0.00104 | 30 | 0.009316 | 48 | Genes involved in Nuclear import of Rev protein | www.broad.mit.e... |
Broad REACTOME_TRANSCRIPTION | View Gene Set | 0.001121 | 188 | 0.009794 | 49 | Genes involved in Transcription | www.broad.mit.e... |
Broad REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | View Gene Set | 0.001139 | 29 | 0.009794 | 49 | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus | www.broad.mit.e... |
Broad REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | View Gene Set | 0.001174 | 29 | 0.009895 | 51 | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery | www.broad.mit.e... |
Broad REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | View Gene Set | 0.001559 | 58 | 0.01265 | 52 | Genes involved in Cyclin E associated events during G1/S transition | www.broad.mit.e... |
Broad REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS | View Gene Set | 0.001558 | 95 | 0.01265 | 52 | Genes involved in Formation of a pool of free 40S subunits | www.broad.mit.e... |
Broad REACTOME_METABLISM_OF_NUCLEOTIDES | View Gene Set | 0.002271 | 71 | 0.01808 | 54 | Genes involved in Metablism of nucleotides | www.broad.mit.e... |
Broad REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | View Gene Set | 0.002354 | 37 | 0.01841 | 55 | Genes involved in Activation of ATR in response to replication stress | www.broad.mit.e... |
Broad REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | View Gene Set | 0.003989 | 30 | 0.03063 | 56 | Genes involved in Activation of the pre-replicative complex | www.broad.mit.e... |
Broad REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION | View Gene Set | 0.004122 | 83 | 0.0311 | 57 | Genes involved in RNA Polymerase II Transcription | www.broad.mit.e... |
Broad REACTOME_APCDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B | View Gene Set | 0.004228 | 18 | 0.03134 | 58 | Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B | www.broad.mit.e... |
Broad REACTOME_VIRAL_MRNA_TRANSLATION | View Gene Set | 0.004737 | 84 | 0.03452 | 59 | Genes involved in Viral mRNA Translation | www.broad.mit.e... |
Broad REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | View Gene Set | 0.005277 | 20 | 0.03747 | 60 | Genes involved in Mitochondrial tRNA aminoacylation | www.broad.mit.e... |
Broad REACTOME_PYRIMIDINE_METABOLISM | View Gene Set | 0.005315 | 22 | 0.03747 | 60 | Genes involved in Pyrimidine metabolism | www.broad.mit.e... |
Broad REACTOME_PEPTIDE_CHAIN_ELONGATION | View Gene Set | 0.006038 | 84 | 0.04188 | 62 | Genes involved in Peptide chain elongation | www.broad.mit.e... |
Broad REACTOME_LAGGING_STRAND_SYNTHESIS | View Gene Set | 0.006155 | 20 | 0.04201 | 63 | Genes involved in Lagging Strand Synthesis | www.broad.mit.e... |
Broad REACTOME_HIV_LIFE_CYCLE | View Gene Set | 0.006702 | 103 | 0.04503 | 64 | Genes involved in HIV Life Cycle | www.broad.mit.e... |
Broad REACTOME_TRANSPORT_OF_THE_SLBP_INDEPENDENT_MATURE_MRNA | View Gene Set | 0.00721 | 32 | 0.0477 | 65 | Genes involved in Transport of the SLBP independent Mature mRNA | www.broad.mit.e... |
Broad REACTOME_CONVERSION_FROM_APC_CDC20_TO_APC_CDH1_IN_LATE_ANAPHASE | View Gene Set | 0.007602 | 17 | 0.04807 | 66 | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | www.broad.mit.e... |
Broad REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR | View Gene Set | 0.007498 | 15 | 0.04807 | 66 | Genes involved in Homologous Recombination Repair | www.broad.mit.e... |
Broad REACTOME_MRNA_SPLICING_MINOR_PATHWAY | View Gene Set | 0.007596 | 38 | 0.04807 | 66 | Genes involved in mRNA Splicing - Minor Pathway | www.broad.mit.e... |
Broad REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | View Gene Set | 0.007981 | 13 | 0.04973 | 69 | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad GCCATNTTG_V$YY1_Q6 | View Gene Set | 1.157e-18 | 289 | 7.115e-16 | 1 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTG which matches annotation for YY1: YY1 transcription factor | www.broad.mit.e... |
Broad V$NFMUE1_Q6 | View Gene Set | 1.807e-10 | 175 | 5.557e-08 | 2 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CGGCCATCT. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$YY1_02 | View Gene Set | 1.155e-07 | 168 | 1.775e-05 | 3 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNCGGCCATCTTGNCTSNW which matches annotation for YY1: YY1 transcription factor | www.broad.mit.e... |
Broad TAANNYSGCG_UNKNOWN | View Gene Set | 8.762e-08 | 60 | 1.775e-05 | 3 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TAANNYSGCG. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F_Q6 | View Gene Set | 2.816e-07 | 165 | 2.887e-05 | 5 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad KCCGNSWTTT_UNKNOWN | View Gene Set | 2.54e-07 | 76 | 2.887e-05 | 5 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KCCGNSWTTT. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F_Q4 | View Gene Set | 5.183e-07 | 166 | 4.554e-05 | 7 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F1_Q6_01 | View Gene Set | 6.951e-06 | 177 | 0.000475 | 8 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTTCGCGCS which matches annotation for E2F1: E2F transcription factor 1 | www.broad.mit.e... |
Broad RCGCANGCGY_V$NRF1_Q6 | View Gene Set | 6.483e-06 | 580 | 0.000475 | 8 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RCGCANGCGY which matches annotation for NRF1: nuclear respiratory factor 1 | www.broad.mit.e... |
Broad V$E2F1_Q6 | View Gene Set | 1.139e-05 | 167 | 0.0007003 | 10 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGS which matches annotation for E2F1: E2F transcription factor 1 | www.broad.mit.e... |
Broad V$YY1_Q6 | View Gene Set | 1.357e-05 | 166 | 0.0007588 | 11 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTN which matches annotation for YY1: YY1 transcription factor | www.broad.mit.e... |
Broad GGCNKCCATNK_UNKNOWN | View Gene Set | 2.957e-05 | 84 | 0.001515 | 12 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGCNKCCATNK. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F1_Q4 | View Gene Set | 4.124e-05 | 178 | 0.001812 | 13 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTSGCGG which matches annotation for E2F1: E2F transcription factor 1 | www.broad.mit.e... |
Broad V$E2F1_Q4_01 | View Gene Set | 3.857e-05 | 167 | 0.001812 | 13 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad SGCGSSAAA_V$E2F1DP2_01 | View Gene Set | 5.082e-05 | 122 | 0.002084 | 15 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SGCGSSAAA which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) | www.broad.mit.e... |
Broad GATGKMRGCG_UNKNOWN | View Gene Set | 7.206e-05 | 47 | 0.00277 | 16 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GATGKMRGCG. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad TCCCRNNRTGC_UNKNOWN | View Gene Set | 0.0001026 | 130 | 0.003711 | 17 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TCCCRNNRTGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad KTGGYRSGAA_UNKNOWN | View Gene Set | 0.000164 | 53 | 0.005604 | 18 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KTGGYRSGAA. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F_Q3_01 | View Gene Set | 0.000185 | 171 | 0.005989 | 19 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad V$E2F_02 | View Gene Set | 0.0002382 | 169 | 0.007134 | 20 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F_Q4_01 | View Gene Set | 0.0002436 | 171 | 0.007134 | 20 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCSCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad V$ELK1_02 | View Gene Set | 0.0003183 | 170 | 0.008155 | 22 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNCCGGAARTNN which matches annotation for ELK1: ELK1 member of ETS oncogene family | www.broad.mit.e... |
Broad AAGWWRNYGGC_UNKNOWN | View Gene Set | 0.0003067 | 85 | 0.008155 | 22 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif AAGWWRNYGGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad TMTCGCGANR_UNKNOWN | View Gene Set | 0.0002954 | 100 | 0.008155 | 22 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TMTCGCGANR. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F1DP1_01 | View Gene Set | 0.0003902 | 169 | 0.008888 | 25 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad V$E2F1DP2_01 | View Gene Set | 0.0003902 | 169 | 0.008888 | 25 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) | www.broad.mit.e... |
Broad V$E2F4DP2_01 | View Gene Set | 0.0003902 | 169 | 0.008888 | 25 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) | www.broad.mit.e... |
Broad V$E2F_Q3 | View Gene Set | 0.0005043 | 162 | 0.01108 | 28 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTCGCGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad GCGSCMNTTT_UNKNOWN | View Gene Set | 0.0008169 | 49 | 0.01732 | 29 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GCGSCMNTTT. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad CCAWNWWNNNGGC_UNKNOWN | View Gene Set | 0.0009164 | 56 | 0.01818 | 30 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CCAWNWWNNNGGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F1DP1RB_01 | View Gene Set | 0.0008968 | 168 | 0.01818 | 30 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) | www.broad.mit.e... |
Broad V$POU3F2_01 | View Gene Set | 0.0009632 | 82 | 0.01851 | 32 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif ATGMATWWATTCAT which matches annotation for POU3F2: POU domain class 3 transcription factor 2 | www.broad.mit.e... |
Broad SCGGAAGY_V$ELK1_02 | View Gene Set | 0.001072 | 784 | 0.01998 | 33 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SCGGAAGY which matches annotation for ELK1: ELK1 member of ETS oncogene family | www.broad.mit.e... |
Broad ACAWNRNSRCGG_UNKNOWN | View Gene Set | 0.001133 | 50 | 0.0205 | 34 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ACAWNRNSRCGG. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F4DP1_01 | View Gene Set | 0.001316 | 174 | 0.02313 | 35 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad GGCKCATGS_UNKNOWN | View Gene Set | 0.001526 | 43 | 0.02606 | 36 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGCKCATGS. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad MGGAAGTG_V$GABP_B | View Gene Set | 0.001773 | 512 | 0.02947 | 37 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif MGGAAGTG which matches annotation for GABPA: GA binding protein transcription factor alpha subunit 60kDa<br> GABPB2: GA binding protein transcription factor beta subunit 2 | www.broad.mit.e... |
Broad V$NRF1_Q6 | View Gene Set | 0.002734 | 151 | 0.04311 | 38 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CGCATGCGCR which matches annotation for NRF1: nuclear respiratory factor 1 | www.broad.mit.e... |
Broad KMCATNNWGGA_UNKNOWN | View Gene Set | 0.002681 | 60 | 0.04311 | 38 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KMCATNNWGGA. Motif does not match any known transcription factor | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad GNF2_CCNA2 | View Gene Set | 2.095e-22 | 62 | 8.945e-20 | 1 | Neighborhood of CCNA2 | www.broad.mit.e... |
Broad GNF2_SMC4L1 | View Gene Set | 6.929e-21 | 75 | 1.479e-18 | 2 | Neighborhood of SMC4L1 | www.broad.mit.e... |
Broad GNF2_RRM1 | View Gene Set | 3.001e-19 | 82 | 4.271e-17 | 3 | Neighborhood of RRM1 | www.broad.mit.e... |
Broad GNF2_PA2G4 | View Gene Set | 5.104e-19 | 73 | 5.449e-17 | 4 | Neighborhood of PA2G4 | www.broad.mit.e... |
Broad GNF2_CCNB2 | View Gene Set | 1.166e-18 | 53 | 8.297e-17 | 5 | Neighborhood of CCNB2 | www.broad.mit.e... |
Broad GNF2_PCNA | View Gene Set | 1.152e-18 | 62 | 8.297e-17 | 5 | Neighborhood of PCNA | www.broad.mit.e... |
Broad GNF2_CDC20 | View Gene Set | 2.488e-18 | 52 | 1.518e-16 | 7 | Neighborhood of CDC20 | www.broad.mit.e... |
Broad MORF_HDAC2 | View Gene Set | 3.646e-18 | 256 | 1.946e-16 | 8 | Neighborhood of HDAC2 | www.broad.mit.e... |
Broad GNF2_CDC2 | View Gene Set | 1.71e-17 | 56 | 8.115e-16 | 9 | Neighborhood of CDC2 | www.broad.mit.e... |
Broad GNF2_HMMR | View Gene Set | 4.206e-17 | 43 | 1.796e-15 | 10 | Neighborhood of HMMR | www.broad.mit.e... |
Broad GNF2_CENPF | View Gene Set | 9.081e-17 | 56 | 3.525e-15 | 11 | Neighborhood of CENPF | www.broad.mit.e... |
Broad GNF2_DEK | View Gene Set | 1.556e-16 | 45 | 5.536e-15 | 12 | Neighborhood of DEK | www.broad.mit.e... |
Broad GNF2_RFC4 | View Gene Set | 5.548e-16 | 57 | 1.822e-14 | 13 | Neighborhood of RFC4 | www.broad.mit.e... |
Broad MORF_PRKDC | View Gene Set | 7.434e-16 | 173 | 2.267e-14 | 14 | Neighborhood of PRKDC | www.broad.mit.e... |
Broad GNF2_MCM5 | View Gene Set | 8.911e-16 | 51 | 2.537e-14 | 15 | Neighborhood of MCM5 | www.broad.mit.e... |
Broad MORF_BUB3 | View Gene Set | 1.024e-15 | 256 | 2.733e-14 | 16 | Neighborhood of BUB3 | www.broad.mit.e... |
Broad GNF2_APEX1 | View Gene Set | 3.066e-15 | 72 | 7.7e-14 | 17 | Neighborhood of APEX1 | www.broad.mit.e... |
Broad GNF2_BUB1B | View Gene Set | 3.364e-15 | 46 | 7.979e-14 | 18 | Neighborhood of BUB1B | www.broad.mit.e... |
Broad MORF_RAD23A | View Gene Set | 1.499e-14 | 316 | 3.368e-13 | 19 | Neighborhood of RAD23A | www.broad.mit.e... |
Broad GNF2_RRM2 | View Gene Set | 1.916e-14 | 36 | 4.092e-13 | 20 | Neighborhood of RRM2 | www.broad.mit.e... |
Broad GNF2_RAN | View Gene Set | 3.781e-14 | 78 | 7.688e-13 | 21 | Neighborhood of RAN | www.broad.mit.e... |
Broad GNF2_MCM4 | View Gene Set | 4.962e-14 | 50 | 9.631e-13 | 22 | Neighborhood of MCM4 | www.broad.mit.e... |
Broad MORF_BUB1B | View Gene Set | 6.443e-14 | 61 | 1.196e-12 | 23 | Neighborhood of BUB1B | www.broad.mit.e... |
Broad GNF2_TTK | View Gene Set | 8.06e-14 | 34 | 1.434e-12 | 24 | Neighborhood of TTK | www.broad.mit.e... |
Broad GNF2_FEN1 | View Gene Set | 1.06e-13 | 49 | 1.811e-12 | 25 | Neighborhood of FEN1 | www.broad.mit.e... |
Broad GNF2_ESPL1 | View Gene Set | 1.422e-13 | 35 | 2.336e-12 | 26 | Neighborhood of ESPL1 | www.broad.mit.e... |
Broad MORF_RFC4 | View Gene Set | 5.727e-13 | 137 | 9.057e-12 | 27 | Neighborhood of RFC4 | www.broad.mit.e... |
Broad GNF2_CKS2 | View Gene Set | 9.814e-13 | 45 | 1.497e-11 | 28 | Neighborhood of CKS2 | www.broad.mit.e... |
Broad MORF_ACP1 | View Gene Set | 1.037e-12 | 178 | 1.528e-11 | 29 | Neighborhood of ACP1 | www.broad.mit.e... |
Broad MORF_DNMT1 | View Gene Set | 1.777e-12 | 105 | 2.505e-11 | 30 | Neighborhood of DNMT1 | www.broad.mit.e... |
Broad GNF2_HDAC1 | View Gene Set | 1.819e-12 | 85 | 2.505e-11 | 30 | Neighborhood of HDAC1 | www.broad.mit.e... |
Broad GNF2_CENPE | View Gene Set | 2.845e-12 | 37 | 3.797e-11 | 32 | Neighborhood of CENPE | www.broad.mit.e... |
Broad GNF2_FBL | View Gene Set | 4.051e-12 | 119 | 5.241e-11 | 33 | Neighborhood of FBL | www.broad.mit.e... |
Broad GNF2_MKI67 | View Gene Set | 6.707e-12 | 26 | 8.423e-11 | 34 | Neighborhood of MKI67 | www.broad.mit.e... |
Broad GNF2_RFC3 | View Gene Set | 7.046e-12 | 38 | 8.596e-11 | 35 | Neighborhood of RFC3 | www.broad.mit.e... |
Broad MORF_FBL | View Gene Set | 1.08e-11 | 121 | 1.28e-10 | 36 | Neighborhood of FBL | www.broad.mit.e... |
Broad GNF2_HAT1 | View Gene Set | 1.478e-11 | 45 | 1.706e-10 | 37 | Neighborhood of HAT1 | www.broad.mit.e... |
Broad MORF_BUB1 | View Gene Set | 1.638e-11 | 49 | 1.841e-10 | 38 | Neighborhood of BUB1 | www.broad.mit.e... |
Broad GNF2_CKS1B | View Gene Set | 3.838e-11 | 36 | 4.202e-10 | 39 | Neighborhood of CKS1B | www.broad.mit.e... |
Broad MORF_UBE2I | View Gene Set | 4.848e-11 | 208 | 5.175e-10 | 40 | Neighborhood of UBE2I | www.broad.mit.e... |
Broad MORF_RAD54L | View Gene Set | 5.046e-11 | 94 | 5.255e-10 | 41 | Neighborhood of RAD54L | www.broad.mit.e... |
Broad MORF_PCNA | View Gene Set | 6.46e-11 | 71 | 6.568e-10 | 42 | Neighborhood of PCNA | www.broad.mit.e... |
Broad GNF2_SMC2L1 | View Gene Set | 7.519e-11 | 30 | 7.467e-10 | 43 | Neighborhood of SMC2L1 | www.broad.mit.e... |
Broad GNF2_KPNB1 | View Gene Set | 1.575e-10 | 52 | 1.529e-09 | 44 | Neighborhood of KPNB1 | www.broad.mit.e... |
Broad MORF_HAT1 | View Gene Set | 1.727e-10 | 155 | 1.638e-09 | 45 | Neighborhood of HAT1 | www.broad.mit.e... |
Broad MORF_SOD1 | View Gene Set | 2.554e-10 | 247 | 2.371e-09 | 46 | Neighborhood of SOD1 | www.broad.mit.e... |
Broad MORF_ESPL1 | View Gene Set | 2.672e-10 | 58 | 2.428e-09 | 47 | Neighborhood of ESPL1 | www.broad.mit.e... |
Broad GNF2_ANP32B | View Gene Set | 2.925e-10 | 29 | 2.602e-09 | 48 | Neighborhood of ANP32B | www.broad.mit.e... |
Broad MORF_DEK | View Gene Set | 3.526e-10 | 229 | 3.073e-09 | 49 | Neighborhood of DEK | www.broad.mit.e... |
Broad MORF_ANP32B | View Gene Set | 4.994e-10 | 174 | 4.265e-09 | 50 | Neighborhood of ANP32B | www.broad.mit.e... |
Broad MORF_EIF3S2 | View Gene Set | 8.609e-10 | 220 | 7.208e-09 | 51 | Neighborhood of EIF3S2 | www.broad.mit.e... |
Broad MORF_RAD21 | View Gene Set | 1.102e-09 | 157 | 9.048e-09 | 52 | Neighborhood of RAD21 | www.broad.mit.e... |
Broad MORF_CSNK2B | View Gene Set | 1.34e-09 | 256 | 1.079e-08 | 53 | Neighborhood of CSNK2B | www.broad.mit.e... |
Broad GNF2_H2AFX | View Gene Set | 1.651e-09 | 28 | 1.306e-08 | 54 | Neighborhood of H2AFX | www.broad.mit.e... |
Broad GNF2_DENR | View Gene Set | 1.729e-09 | 39 | 1.342e-08 | 55 | Neighborhood of DENR | www.broad.mit.e... |
Broad MORF_AATF | View Gene Set | 1.783e-09 | 179 | 1.359e-08 | 56 | Neighborhood of AATF | www.broad.mit.e... |
Broad MORF_PPP1CC | View Gene Set | 3.489e-09 | 150 | 2.613e-08 | 57 | Neighborhood of PPP1CC | www.broad.mit.e... |
Broad GNF2_DAP3 | View Gene Set | 4.443e-09 | 98 | 3.271e-08 | 58 | Neighborhood of DAP3 | www.broad.mit.e... |
Broad MORF_GNB1 | View Gene Set | 5.694e-09 | 276 | 4.121e-08 | 59 | Neighborhood of GNB1 | www.broad.mit.e... |
Broad GNF2_TDG | View Gene Set | 7.93e-09 | 23 | 5.643e-08 | 60 | Neighborhood of TDG | www.broad.mit.e... |
Broad MORF_DDB1 | View Gene Set | 8.857e-09 | 220 | 6.2e-08 | 61 | Neighborhood of DDB1 | www.broad.mit.e... |
Broad GNF2_RBBP6 | View Gene Set | 1.018e-08 | 54 | 7.011e-08 | 62 | Neighborhood of RBBP6 | www.broad.mit.e... |
Broad GNF2_MSH2 | View Gene Set | 1.239e-08 | 26 | 8.395e-08 | 63 | Neighborhood of MSH2 | www.broad.mit.e... |
Broad GNF2_XRCC5 | View Gene Set | 1.405e-08 | 61 | 9.374e-08 | 64 | Neighborhood of XRCC5 | www.broad.mit.e... |
Broad GNF2_BUB1 | View Gene Set | 1.635e-08 | 25 | 1.074e-07 | 65 | Neighborhood of BUB1 | www.broad.mit.e... |
Broad MORF_MSH2 | View Gene Set | 1.731e-08 | 52 | 1.12e-07 | 66 | Neighborhood of MSH2 | www.broad.mit.e... |
Broad MORF_PRKAG1 | View Gene Set | 1.791e-08 | 202 | 1.141e-07 | 67 | Neighborhood of PRKAG1 | www.broad.mit.e... |
Broad MORF_XRCC5 | View Gene Set | 3.557e-08 | 210 | 2.234e-07 | 68 | Neighborhood of XRCC5 | www.broad.mit.e... |
Broad MORF_RRM1 | View Gene Set | 5.139e-08 | 90 | 3.18e-07 | 69 | Neighborhood of RRM1 | www.broad.mit.e... |
Broad MORF_UNG | View Gene Set | 8.615e-08 | 65 | 5.255e-07 | 70 | Neighborhood of UNG | www.broad.mit.e... |
Broad MORF_PSMC1 | View Gene Set | 1.237e-07 | 162 | 7.44e-07 | 71 | Neighborhood of PSMC1 | www.broad.mit.e... |
Broad GNF2_MLH1 | View Gene Set | 1.444e-07 | 36 | 8.563e-07 | 72 | Neighborhood of MLH1 | www.broad.mit.e... |
Broad MORF_FEN1 | View Gene Set | 1.466e-07 | 58 | 8.576e-07 | 73 | Neighborhood of FEN1 | www.broad.mit.e... |
Broad MORF_G22P1 | View Gene Set | 1.539e-07 | 145 | 8.882e-07 | 74 | Neighborhood of G22P1 | www.broad.mit.e... |
Broad GNF2_RPA1 | View Gene Set | 1.784e-07 | 20 | 1.016e-06 | 75 | Neighborhood of RPA1 | www.broad.mit.e... |
Broad MORF_SKP1A | View Gene Set | 6.798e-07 | 175 | 3.82e-06 | 76 | Neighborhood of SKP1A | www.broad.mit.e... |
Broad MORF_SMC1L1 | View Gene Set | 9.152e-07 | 47 | 5.075e-06 | 77 | Neighborhood of SMC1L1 | www.broad.mit.e... |
Broad MORF_SNRP70 | View Gene Set | 1.076e-06 | 50 | 5.893e-06 | 78 | Neighborhood of SNRP70 | www.broad.mit.e... |
Broad GCM_APEX1 | View Gene Set | 1.21e-06 | 102 | 6.542e-06 | 79 | Neighborhood of APEX1 | www.broad.mit.e... |
Broad GNF2_ELAC2 | View Gene Set | 1.297e-06 | 32 | 6.924e-06 | 80 | Neighborhood of ELAC2 | www.broad.mit.e... |
Broad GNF2_G22P1 | View Gene Set | 1.378e-06 | 29 | 7.263e-06 | 81 | Neighborhood of G22P1 | www.broad.mit.e... |
Broad MORF_UBE2N | View Gene Set | 2.11e-06 | 79 | 1.099e-05 | 82 | Neighborhood of UBE2N | www.broad.mit.e... |
Broad MORF_RAN | View Gene Set | 2.557e-06 | 242 | 1.3e-05 | 83 | Neighborhood of RAN | www.broad.mit.e... |
Broad GNF2_PPP6C | View Gene Set | 2.554e-06 | 33 | 1.3e-05 | 83 | Neighborhood of PPP6C | www.broad.mit.e... |
Broad MORF_CDC16 | View Gene Set | 2.885e-06 | 67 | 1.435e-05 | 85 | Neighborhood of CDC16 | www.broad.mit.e... |
Broad MORF_PHB | View Gene Set | 2.89e-06 | 112 | 1.435e-05 | 85 | Neighborhood of PHB | www.broad.mit.e... |
Broad MORF_DAP3 | View Gene Set | 3.67e-06 | 175 | 1.801e-05 | 87 | Neighborhood of DAP3 | www.broad.mit.e... |
Broad MORF_RPA2 | View Gene Set | 4.975e-06 | 170 | 2.414e-05 | 88 | Neighborhood of RPA2 | www.broad.mit.e... |
Broad GNF2_MSH6 | View Gene Set | 5.234e-06 | 30 | 2.511e-05 | 89 | Neighborhood of MSH6 | www.broad.mit.e... |
Broad MORF_CUL1 | View Gene Set | 5.713e-06 | 62 | 2.711e-05 | 90 | Neighborhood of CUL1 | www.broad.mit.e... |
Broad MORF_EI24 | View Gene Set | 5.862e-06 | 136 | 2.75e-05 | 91 | Neighborhood of EI24 | www.broad.mit.e... |
Broad MORF_RAD23B | View Gene Set | 6.066e-06 | 159 | 2.815e-05 | 92 | Neighborhood of RAD23B | www.broad.mit.e... |
Broad MORF_MTA1 | View Gene Set | 6.874e-06 | 95 | 3.156e-05 | 93 | Neighborhood of MTA1 | www.broad.mit.e... |
Broad MORF_PPP2CA | View Gene Set | 7.943e-06 | 110 | 3.608e-05 | 94 | Neighborhood of PPP2CA | www.broad.mit.e... |
Broad MORF_PPP1CA | View Gene Set | 8.177e-06 | 145 | 3.675e-05 | 95 | Neighborhood of PPP1CA | www.broad.mit.e... |
Broad MORF_RPA1 | View Gene Set | 8.362e-06 | 55 | 3.719e-05 | 96 | Neighborhood of RPA1 | www.broad.mit.e... |
Broad GCM_MAX | View Gene Set | 8.547e-06 | 28 | 3.762e-05 | 97 | Neighborhood of MAX | www.broad.mit.e... |
Broad GCM_DENR | View Gene Set | 8.866e-06 | 40 | 3.863e-05 | 98 | Neighborhood of DENR | www.broad.mit.e... |
Broad GNF2_NPM1 | View Gene Set | 1.022e-05 | 57 | 4.407e-05 | 99 | Neighborhood of NPM1 | www.broad.mit.e... |
Broad MORF_HDAC1 | View Gene Set | 1.062e-05 | 222 | 4.533e-05 | 100 | Neighborhood of HDAC1 | www.broad.mit.e... |
Broad MORF_RAF1 | View Gene Set | 1.182e-05 | 94 | 4.996e-05 | 101 | Neighborhood of RAF1 | www.broad.mit.e... |
Broad MORF_SART1 | View Gene Set | 1.244e-05 | 55 | 5.209e-05 | 102 | Neighborhood of SART1 | www.broad.mit.e... |
Broad MORF_GSPT1 | View Gene Set | 1.39e-05 | 41 | 5.764e-05 | 103 | Neighborhood of GSPT1 | www.broad.mit.e... |
Broad MORF_CCNF | View Gene Set | 1.706e-05 | 65 | 7.006e-05 | 104 | Neighborhood of CCNF | www.broad.mit.e... |
Broad MORF_GMPS | View Gene Set | 1.936e-05 | 48 | 7.871e-05 | 105 | Neighborhood of GMPS | www.broad.mit.e... |
Broad MORF_TERF1 | View Gene Set | 2.398e-05 | 57 | 9.662e-05 | 106 | Neighborhood of TERF1 | www.broad.mit.e... |
Broad MORF_CTBP1 | View Gene Set | 2.531e-05 | 149 | 0.000101 | 107 | Neighborhood of CTBP1 | www.broad.mit.e... |
Broad MORF_ERH | View Gene Set | 2.588e-05 | 103 | 0.0001023 | 108 | Neighborhood of ERH | www.broad.mit.e... |
Broad MORF_EIF4A2 | View Gene Set | 3.017e-05 | 120 | 0.0001182 | 109 | Neighborhood of EIF4A2 | www.broad.mit.e... |
Broad MORF_RAC1 | View Gene Set | 3.53e-05 | 196 | 0.000137 | 110 | Neighborhood of RAC1 | www.broad.mit.e... |
Broad MORF_NPM1 | View Gene Set | 4.169e-05 | 152 | 0.0001604 | 111 | Neighborhood of NPM1 | www.broad.mit.e... |
Broad MORF_PTPN11 | View Gene Set | 4.527e-05 | 93 | 0.0001726 | 112 | Neighborhood of PTPN11 | www.broad.mit.e... |
Broad MORF_EIF4E | View Gene Set | 5.316e-05 | 76 | 0.0002009 | 113 | Neighborhood of EIF4E | www.broad.mit.e... |
Broad MORF_PSMC2 | View Gene Set | 5.942e-05 | 100 | 0.0002215 | 114 | Neighborhood of PSMC2 | www.broad.mit.e... |
Broad GCM_MYST2 | View Gene Set | 5.965e-05 | 138 | 0.0002215 | 114 | Neighborhood of MYST2 | www.broad.mit.e... |
Broad GNF2_BNIP2 | View Gene Set | 6.492e-05 | 31 | 0.000239 | 116 | Neighborhood of BNIP2 | www.broad.mit.e... |
Broad GNF2_NS | View Gene Set | 7.511e-05 | 35 | 0.0002741 | 117 | Neighborhood of NS | www.broad.mit.e... |
Broad MORF_SP3 | View Gene Set | 8.29e-05 | 69 | 0.0003 | 118 | Neighborhood of SP3 | www.broad.mit.e... |
Broad MORF_EIF3S6 | View Gene Set | 8.54e-05 | 108 | 0.0003064 | 119 | Neighborhood of EIF3S6 | www.broad.mit.e... |
Broad GCM_CBFB | View Gene Set | 9.588e-05 | 59 | 0.0003412 | 120 | Neighborhood of CBFB | www.broad.mit.e... |
Broad MORF_CCNI | View Gene Set | 0.0001173 | 76 | 0.0004138 | 121 | Neighborhood of CCNI | www.broad.mit.e... |
Broad MORF_DEAF1 | View Gene Set | 0.0001292 | 54 | 0.0004522 | 122 | Neighborhood of DEAF1 | www.broad.mit.e... |
Broad GNF2_BUB3 | View Gene Set | 0.0001445 | 22 | 0.0005015 | 123 | Neighborhood of BUB3 | www.broad.mit.e... |
Broad MORF_CDC10 | View Gene Set | 0.0001717 | 120 | 0.0005911 | 124 | Neighborhood of CDC10 | www.broad.mit.e... |
Broad GNF2_EIF3S6 | View Gene Set | 0.0001773 | 109 | 0.0006057 | 125 | Neighborhood of EIF3S6 | www.broad.mit.e... |
Broad MORF_SS18 | View Gene Set | 0.0001999 | 55 | 0.0006776 | 126 | Neighborhood of SS18 | www.broad.mit.e... |
Broad GCM_MLL | View Gene Set | 0.0002797 | 130 | 0.0009404 | 127 | Neighborhood of MLL | www.broad.mit.e... |
Broad MORF_TERF2IP | View Gene Set | 0.0002907 | 99 | 0.0009697 | 128 | Neighborhood of TERF2IP | www.broad.mit.e... |
Broad MORF_REV3L | View Gene Set | 0.0002995 | 52 | 0.0009915 | 129 | Neighborhood of REV3L | www.broad.mit.e... |
Broad GCM_DFFA | View Gene Set | 0.0003509 | 100 | 0.001153 | 130 | Neighborhood of DFFA | www.broad.mit.e... |
Broad GCM_HBP1 | View Gene Set | 0.0003796 | 54 | 0.001237 | 131 | Neighborhood of HBP1 | www.broad.mit.e... |
Broad MORF_BAG5 | View Gene Set | 0.0004179 | 48 | 0.001352 | 132 | Neighborhood of BAG5 | www.broad.mit.e... |
Broad GCM_SMARCC1 | View Gene Set | 0.0004438 | 33 | 0.001425 | 133 | Neighborhood of SMARCC1 | www.broad.mit.e... |
Broad GCM_ANP32B | View Gene Set | 0.000548 | 32 | 0.001746 | 134 | Neighborhood of ANP32B | www.broad.mit.e... |
Broad MORF_CDK2 | View Gene Set | 0.0006952 | 63 | 0.002199 | 135 | Neighborhood of CDK2 | www.broad.mit.e... |
Broad MORF_FANCG | View Gene Set | 0.0007423 | 148 | 0.002331 | 136 | Neighborhood of FANCG | www.broad.mit.e... |
Broad GCM_NPM1 | View Gene Set | 0.0008533 | 108 | 0.00266 | 137 | Neighborhood of NPM1 | www.broad.mit.e... |
Broad MORF_ACTG1 | View Gene Set | 0.000875 | 134 | 0.002707 | 138 | Neighborhood of ACTG1 | www.broad.mit.e... |
Broad GNF2_ST13 | View Gene Set | 0.0008969 | 56 | 0.002755 | 139 | Neighborhood of ST13 | www.broad.mit.e... |
Broad MORF_PPP6C | View Gene Set | 0.0009341 | 88 | 0.002849 | 140 | Neighborhood of PPP6C | www.broad.mit.e... |
Broad GCM_ACTG1 | View Gene Set | 0.000957 | 113 | 0.002898 | 141 | Neighborhood of ACTG1 | www.broad.mit.e... |
Broad GNF2_UBE2I | View Gene Set | 0.001002 | 33 | 0.003012 | 142 | Neighborhood of UBE2I | www.broad.mit.e... |
Broad GCM_PSME1 | View Gene Set | 0.001052 | 76 | 0.003141 | 143 | Neighborhood of PSME1 | www.broad.mit.e... |
Broad GCM_NF2 | View Gene Set | 0.001069 | 235 | 0.00317 | 144 | Neighborhood of NF2 | www.broad.mit.e... |
Broad GCM_HDAC1 | View Gene Set | 0.001106 | 30 | 0.003235 | 145 | Neighborhood of HDAC1 | www.broad.mit.e... |
Broad GCM_NUMA1 | View Gene Set | 0.001104 | 45 | 0.003235 | 145 | Neighborhood of NUMA1 | www.broad.mit.e... |
Broad GCM_BECN1 | View Gene Set | 0.001115 | 59 | 0.003239 | 147 | Neighborhood of BECN1 | www.broad.mit.e... |
Broad GCM_DDX5 | View Gene Set | 0.001161 | 52 | 0.00335 | 148 | Neighborhood of DDX5 | www.broad.mit.e... |
Broad GNF2_CBFB | View Gene Set | 0.001243 | 26 | 0.003561 | 149 | Neighborhood of CBFB | www.broad.mit.e... |
Broad GCM_DPF2 | View Gene Set | 0.001401 | 32 | 0.003989 | 150 | Neighborhood of DPF2 | www.broad.mit.e... |
Broad MORF_RFC1 | View Gene Set | 0.001449 | 98 | 0.004096 | 151 | Neighborhood of RFC1 | www.broad.mit.e... |
Broad GNF2_DDX5 | View Gene Set | 0.001591 | 54 | 0.004468 | 152 | Neighborhood of DDX5 | www.broad.mit.e... |
Broad MORF_PPP5C | View Gene Set | 0.001629 | 81 | 0.004547 | 153 | Neighborhood of PPP5C | www.broad.mit.e... |
Broad GCM_CSNK1A1 | View Gene Set | 0.001816 | 28 | 0.005036 | 154 | Neighborhood of CSNK1A1 | www.broad.mit.e... |
Broad MORF_PRKAR1A | View Gene Set | 0.001975 | 133 | 0.005406 | 155 | Neighborhood of PRKAR1A | www.broad.mit.e... |
Broad GNF2_SMC1L1 | View Gene Set | 0.001969 | 24 | 0.005406 | 155 | Neighborhood of SMC1L1 | www.broad.mit.e... |
Broad MORF_TPR | View Gene Set | 0.002009 | 131 | 0.005465 | 157 | Neighborhood of TPR | www.broad.mit.e... |
Broad MORF_NME2 | View Gene Set | 0.002503 | 145 | 0.006764 | 158 | Neighborhood of NME2 | www.broad.mit.e... |
Broad MORF_USP5 | View Gene Set | 0.002836 | 46 | 0.007617 | 159 | Neighborhood of USP5 | www.broad.mit.e... |
Broad GCM_UBE2N | View Gene Set | 0.002905 | 125 | 0.007752 | 160 | Neighborhood of UBE2N | www.broad.mit.e... |
Broad GCM_PPP1CC | View Gene Set | 0.003066 | 47 | 0.008131 | 161 | Neighborhood of PPP1CC | www.broad.mit.e... |
Broad GCM_AIP | View Gene Set | 0.003102 | 36 | 0.008176 | 162 | Neighborhood of AIP | www.broad.mit.e... |
Broad MORF_PRDX3 | View Gene Set | 0.003361 | 79 | 0.008804 | 163 | Neighborhood of PRDX3 | www.broad.mit.e... |
Broad GNF2_TYK2 | View Gene Set | 0.003576 | 31 | 0.009311 | 164 | Neighborhood of TYK2 | www.broad.mit.e... |
Broad GCM_GSPT1 | View Gene Set | 0.003963 | 129 | 0.01026 | 165 | Neighborhood of GSPT1 | www.broad.mit.e... |
Broad GCM_RAF1 | View Gene Set | 0.00403 | 34 | 0.01037 | 166 | Neighborhood of RAF1 | www.broad.mit.e... |
Broad GCM_CHUK | View Gene Set | 0.004162 | 61 | 0.01064 | 167 | Neighborhood of CHUK | www.broad.mit.e... |
Broad MORF_MBD4 | View Gene Set | 0.004368 | 76 | 0.0111 | 168 | Neighborhood of MBD4 | www.broad.mit.e... |
Broad GCM_CSNK2B | View Gene Set | 0.004901 | 88 | 0.01238 | 169 | Neighborhood of CSNK2B | www.broad.mit.e... |
Broad MORF_ORC1L | View Gene Set | 0.006692 | 61 | 0.01681 | 170 | Neighborhood of ORC1L | www.broad.mit.e... |
Broad MORF_MAP2K2 | View Gene Set | 0.006868 | 123 | 0.01715 | 171 | Neighborhood of MAP2K2 | www.broad.mit.e... |
Broad GCM_PRKAG1 | View Gene Set | 0.007374 | 49 | 0.01831 | 172 | Neighborhood of PRKAG1 | www.broad.mit.e... |
Broad MORF_ATOX1 | View Gene Set | 0.007573 | 72 | 0.01869 | 173 | Neighborhood of ATOX1 | www.broad.mit.e... |
Broad GCM_VAV1 | View Gene Set | 0.008275 | 46 | 0.02031 | 174 | Neighborhood of VAV1 | www.broad.mit.e... |
Broad MORF_AP3D1 | View Gene Set | 0.008355 | 119 | 0.02039 | 175 | Neighborhood of AP3D1 | www.broad.mit.e... |
Broad MORF_HEAB | View Gene Set | 0.00991 | 71 | 0.02404 | 176 | Neighborhood of HEAB | www.broad.mit.e... |
Broad MORF_AP2M1 | View Gene Set | 0.01034 | 197 | 0.02495 | 177 | Neighborhood of AP2M1 | www.broad.mit.e... |
Broad GCM_PPM1D | View Gene Set | 0.01355 | 22 | 0.03251 | 178 | Neighborhood of PPM1D | www.broad.mit.e... |
Broad GCM_RBM8A | View Gene Set | 0.01429 | 64 | 0.03409 | 179 | Neighborhood of RBM8A | www.broad.mit.e... |
Broad MORF_BMI1 | View Gene Set | 0.01469 | 71 | 0.03469 | 180 | Neighborhood of BMI1 | www.broad.mit.e... |
Broad GCM_PFN1 | View Gene Set | 0.0147 | 47 | 0.03469 | 180 | Neighborhood of PFN1 | www.broad.mit.e... |
Broad MORF_TPT1 | View Gene Set | 0.01576 | 100 | 0.03698 | 182 | Neighborhood of TPT1 | www.broad.mit.e... |
Broad MORF_PPP2R5E | View Gene Set | 0.01703 | 76 | 0.03973 | 183 | Neighborhood of PPP2R5E | www.broad.mit.e... |
Broad GCM_RAD21 | View Gene Set | 0.01846 | 30 | 0.04283 | 184 | Neighborhood of RAD21 | www.broad.mit.e... |
Broad MORF_JUND | View Gene Set | 0.01878 | 63 | 0.04326 | 185 | Neighborhood of JUND | www.broad.mit.e... |
Broad MORF_RAB11A | View Gene Set | 0.01884 | 53 | 0.04326 | 185 | Neighborhood of RAB11A | www.broad.mit.e... |
Broad GCM_RING1 | View Gene Set | 0.02004 | 106 | 0.04576 | 187 | Neighborhood of RING1 | www.broad.mit.e... |
Broad GCM_TPT1 | View Gene Set | 0.02147 | 69 | 0.04876 | 188 | Neighborhood of TPT1 | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad module_252 | View Gene Set | 4.258e-14 | 224 | 1.933e-11 | 1 | Genes in module_252 | www.broad.mit.e... |
Broad module_198 | View Gene Set | 9.883e-14 | 288 | 2.243e-11 | 2 | Genes in module_198 | www.broad.mit.e... |
Broad module_98 | View Gene Set | 5.764e-13 | 375 | 8.722e-11 | 3 | Genes in module_98 | www.broad.mit.e... |
Broad module_54 | View Gene Set | 3.259e-12 | 242 | 3.699e-10 | 4 | Genes in module_54 | www.broad.mit.e... |
Broad module_183 | View Gene Set | 1.596e-11 | 52 | 1.449e-09 | 5 | Genes in module_183 | www.broad.mit.e... |
Broad module_17 | View Gene Set | 1.246e-07 | 351 | 9.426e-06 | 6 | Genes in module_17 | www.broad.mit.e... |
Broad module_403 | View Gene Set | 2.699e-07 | 44 | 1.751e-05 | 7 | Genes in module_403 | www.broad.mit.e... |
Broad module_8 | View Gene Set | 8.23e-07 | 403 | 4.67e-05 | 8 | Genes in module_8 | www.broad.mit.e... |
Broad module_57 | View Gene Set | 4.634e-06 | 54 | 0.0002338 | 9 | Genes in module_57 | www.broad.mit.e... |
Broad module_91 | View Gene Set | 5.472e-06 | 37 | 0.0002456 | 10 | Genes in module_91 | www.broad.mit.e... |
Broad module_158 | View Gene Set | 5.952e-06 | 41 | 0.0002456 | 10 | Genes in module_158 | www.broad.mit.e... |
Broad module_125 | View Gene Set | 1.25e-05 | 42 | 0.000473 | 12 | Genes in module_125 | www.broad.mit.e... |
Broad module_28 | View Gene Set | 2.021e-05 | 32 | 0.0007058 | 13 | Genes in module_28 | www.broad.mit.e... |
Broad module_32 | View Gene Set | 2.436e-05 | 227 | 0.00079 | 14 | Genes in module_32 | www.broad.mit.e... |
Broad module_197 | View Gene Set | 6.319e-05 | 170 | 0.001913 | 15 | Genes in module_197 | www.broad.mit.e... |
Broad module_124 | View Gene Set | 9.605e-05 | 92 | 0.002725 | 16 | Genes in module_124 | www.broad.mit.e... |
Broad module_337 | View Gene Set | 0.0001243 | 59 | 0.003319 | 17 | Genes in module_337 | www.broad.mit.e... |
Broad module_18 | View Gene Set | 0.0001325 | 434 | 0.003341 | 18 | Genes in module_18 | www.broad.mit.e... |
Broad module_451 | View Gene Set | 0.0001998 | 29 | 0.004774 | 19 | Genes in module_451 | www.broad.mit.e... |
Broad module_126 | View Gene Set | 0.0002185 | 173 | 0.004959 | 20 | Genes in module_126 | www.broad.mit.e... |
Broad module_352 | View Gene Set | 0.0002326 | 17 | 0.005029 | 21 | Genes in module_352 | www.broad.mit.e... |
Broad module_320 | View Gene Set | 0.000625 | 19 | 0.0129 | 22 | Genes in module_320 | www.broad.mit.e... |
Broad module_219 | View Gene Set | 0.0006537 | 26 | 0.0129 | 23 | Genes in module_219 | www.broad.mit.e... |
Broad module_278 | View Gene Set | 0.000761 | 34 | 0.01382 | 24 | Genes in module_278 | www.broad.mit.e... |
Broad module_397 | View Gene Set | 0.0007447 | 114 | 0.01382 | 24 | Genes in module_397 | www.broad.mit.e... |
Broad module_315 | View Gene Set | 0.0009091 | 15 | 0.01587 | 26 | Genes in module_315 | www.broad.mit.e... |
Broad module_3 | View Gene Set | 0.0013 | 374 | 0.02107 | 27 | Genes in module_3 | www.broad.mit.e... |
Broad module_102 | View Gene Set | 0.001261 | 18 | 0.02107 | 27 | Genes in module_102 | www.broad.mit.e... |
Broad module_42 | View Gene Set | 0.002706 | 25 | 0.03963 | 29 | Genes in module_42 | www.broad.mit.e... |
Broad module_244 | View Gene Set | 0.002534 | 182 | 0.03963 | 29 | Genes in module_244 | www.broad.mit.e... |
Broad module_388 | View Gene Set | 0.002638 | 17 | 0.03963 | 29 | Genes in module_388 | www.broad.mit.e... |
Broad module_25 | View Gene Set | 0.003181 | 13 | 0.04513 | 32 | Genes in module_25 | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | View Gene Set | 7.142e-21 | 1197 | 5.892e-18 | 1 | Genes annotated by the GO term GO:0006139. The chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. | www.broad.mit.e... |
Broad RNA_METABOLIC_PROCESS | View Gene Set | 1.527e-16 | 801 | 6.298e-14 | 2 | Genes annotated by the GO term GO:0016070. The chemical reactions and pathways involving RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. | www.broad.mit.e... |
Broad BIOPOLYMER_METABOLIC_PROCESS | View Gene Set | 6.142e-13 | 1623 | 1.689e-10 | 3 | Genes annotated by the GO term GO:0043283. The chemical reactions and pathways involving biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. | www.broad.mit.e... |
Broad RNA_PROCESSING | View Gene Set | 1.533e-12 | 147 | 3.161e-10 | 4 | Genes annotated by the GO term GO:0006396. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. | www.broad.mit.e... |
Broad MITOTIC_CELL_CYCLE | View Gene Set | 3.59e-12 | 148 | 5.445e-10 | 5 | Genes annotated by the GO term GO:0000278. Progression through the phases of the mitotic cell cycle the most common eukaryotic cell cycle which canonically comprises four successive phases called G1 S G2 and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division or G1 and G2 phases may be absent. | www.broad.mit.e... |
Broad M_PHASE_OF_MITOTIC_CELL_CYCLE | View Gene Set | 3.96e-12 | 83 | 5.445e-10 | 5 | Genes annotated by the GO term GO:0000087. Progression through M phase the part of the mitotic cell cycle during which mitosis takes place. | www.broad.mit.e... |
Broad M_PHASE | View Gene Set | 9.301e-12 | 111 | 1.096e-09 | 7 | Genes annotated by the GO term GO:0000279. Progression through M phase the part of the cell cycle comprising nuclear division. | www.broad.mit.e... |
Broad CELL_CYCLE_PROCESS | View Gene Set | 1.33e-11 | 187 | 1.372e-09 | 8 | Genes annotated by the GO term GO:0022402. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. | www.broad.mit.e... |
Broad MITOSIS | View Gene Set | 1.692e-11 | 81 | 1.551e-09 | 9 | Genes annotated by the GO term GO:0007067. Progression through mitosis the division of the eukaryotic cell nucleus to produce two daughter nuclei that usually contain the identical chromosome complement to their mother. | www.broad.mit.e... |
Broad CELL_CYCLE_PHASE | View Gene Set | 4.751e-10 | 167 | 3.697e-08 | 10 | Genes annotated by the GO term GO:0022403. A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. | www.broad.mit.e... |
Broad RNA_SPLICING | View Gene Set | 4.929e-10 | 73 | 3.697e-08 | 10 | Genes annotated by the GO term GO:0008380. The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. | www.broad.mit.e... |
Broad DNA_METABOLIC_PROCESS | View Gene Set | 1.043e-08 | 253 | 7.171e-07 | 12 | Genes annotated by the GO term GO:0006259. The chemical reactions and pathways involving DNA deoxyribonucleic acid one of the two main types of nucleic acid consisting of a long unbranched macromolecule formed from one or more commonly two strands of linked deoxyribonucleotides. | www.broad.mit.e... |
Broad TRANSCRIPTION | View Gene Set | 2.565e-08 | 738 | 1.606e-06 | 13 | Genes annotated by the GO term GO:0006350. The synthesis of either RNA on a template of DNA or DNA on a template of RNA. | www.broad.mit.e... |
Broad CHROMOSOME_ORGANIZATION_AND_BIOGENESIS | View Gene Set | 2.726e-08 | 117 | 1.606e-06 | 13 | Genes annotated by the GO term GO:0051276. A process that is carried out at the cellular level that results in the formation arrangement of constituent parts or disassembly of chromosomes structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. | www.broad.mit.e... |
Broad CELL_CYCLE_GO_0007049 | View Gene Set | 6.796e-08 | 304 | 3.738e-06 | 15 | Genes annotated by the GO term GO:0007049. The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. | www.broad.mit.e... |
Broad REGULATION_OF_GENE_EXPRESSION | View Gene Set | 7.422e-08 | 660 | 3.827e-06 | 16 | Genes annotated by the GO term GO:0010468. Any process that modulates the frequency rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. | www.broad.mit.e... |
Broad TRANSCRIPTION_DNA_DEPENDENT | View Gene Set | 9.047e-08 | 623 | 4.146e-06 | 17 | Genes annotated by the GO term GO:0006351. The synthesis of RNA on a template of DNA. | www.broad.mit.e... |
Broad RNA_BIOSYNTHETIC_PROCESS | View Gene Set | 8.655e-08 | 625 | 4.146e-06 | 17 | Genes annotated by the GO term GO:0032774. The chemical reactions and pathways resulting in the formation of RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. | www.broad.mit.e... |
Broad REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | View Gene Set | 2.552e-07 | 601 | 1.108e-05 | 19 | Genes annotated by the GO term GO:0019219. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. | www.broad.mit.e... |
Broad REGULATION_OF_TRANSCRIPTION | View Gene Set | 8.496e-07 | 555 | 3.504e-05 | 20 | Genes annotated by the GO term GO:0045449. Any process that modulates the frequency rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. | www.broad.mit.e... |
Broad REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT | View Gene Set | 3.442e-06 | 452 | 0.0001352 | 21 | Genes annotated by the GO term GO:0006355. Any process that modulates the frequency rate or extent of DNA-dependent transcription. | www.broad.mit.e... |
Broad REGULATION_OF_RNA_METABOLIC_PROCESS | View Gene Set | 4.502e-06 | 457 | 0.0001688 | 22 | Genes annotated by the GO term GO:0051252. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving RNA. | www.broad.mit.e... |
Broad REGULATION_OF_CELLULAR_METABOLIC_PROCESS | View Gene Set | 6.146e-06 | 767 | 0.0002205 | 23 | Genes annotated by the GO term GO:0031323. Any process that modulates the frequency rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. | www.broad.mit.e... |
Broad REGULATION_OF_METABOLIC_PROCESS | View Gene Set | 9.88e-06 | 779 | 0.0003396 | 24 | Genes annotated by the GO term GO:0019222. Any process that modulates the frequency rate or extent of the chemical reactions and pathways within a cell or an organism. | www.broad.mit.e... |
Broad MITOTIC_SPINDLE_ORGANIZATION_AND_BIOGENESIS | View Gene Set | 1.448e-05 | 9 | 0.0004777 | 25 | Genes annotated by the GO term GO:0007052. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the microtubule spindle during a mitotic cell cycle. | www.broad.mit.e... |
Broad TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | View Gene Set | 1.784e-05 | 449 | 0.0005662 | 26 | Genes annotated by the GO term GO:0006366. The synthesis of RNA from a DNA template by RNA polymerase II (Pol II) originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_TRANSCRIPTION_DNA_DEPENDENT | View Gene Set | 2.408e-05 | 127 | 0.000685 | 27 | Genes annotated by the GO term GO:0045892. Any process that stops prevents or reduces the frequency rate or extent of DNA-dependent transcription. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | View Gene Set | 2.408e-05 | 127 | 0.000685 | 27 | Genes annotated by the GO term GO:0051253. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways involving RNA. | www.broad.mit.e... |
Broad SPINDLE_ORGANIZATION_AND_BIOGENESIS | View Gene Set | 2.304e-05 | 10 | 0.000685 | 27 | Genes annotated by the GO term GO:0007051. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the spindle the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. | www.broad.mit.e... |
Broad MITOTIC_SISTER_CHROMATID_SEGREGATION | View Gene Set | 3.068e-05 | 16 | 0.0008438 | 30 | Genes annotated by the GO term GO:0000070. The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome composed of two sister chromatids aligns at the cell equator paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. | www.broad.mit.e... |
Broad SISTER_CHROMATID_SEGREGATION | View Gene Set | 3.352e-05 | 17 | 0.000892 | 31 | Genes annotated by the GO term GO:0000819. The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets. | www.broad.mit.e... |
Broad DNA_REPAIR | View Gene Set | 3.879e-05 | 123 | 0.0009999 | 32 | Genes annotated by the GO term GO:0006281. The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations chemical mutagens fungal and bacterial toxins etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal base excision repair nucleotide excision repair photoreactivation bypass double-strand break repair pathway and mismatch repair pathway. | www.broad.mit.e... |
Broad ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CHROMATIN_ARCHITECTURE | View Gene Set | 4.336e-05 | 72 | 0.001084 | 33 | Genes annotated by the GO term GO:0006325. The specification formation and maintenance of the physical structure of eukaryotic chromatin. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | View Gene Set | 4.805e-05 | 205 | 0.001133 | 34 | Genes annotated by the GO term GO:0045934. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_TRANSCRIPTION | View Gene Set | 4.709e-05 | 185 | 0.001133 | 34 | Genes annotated by the GO term GO:0016481. Any process that stops prevents or reduces the frequency rate or extent of transcription. | www.broad.mit.e... |
Broad RESPONSE_TO_DNA_DAMAGE_STIMULUS | View Gene Set | 5.774e-05 | 159 | 0.001323 | 36 | Genes annotated by the GO term GO:0006974. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | View Gene Set | 5.946e-05 | 83 | 0.001326 | 37 | Genes annotated by the GO term GO:0000122. Any process that stops prevents or reduces the frequency rate or extent of transcription from an RNA polymerase II promoter. | www.broad.mit.e... |
Broad REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | View Gene Set | 8.295e-05 | 285 | 0.001801 | 38 | Genes annotated by the GO term GO:0006357. Any process that modulates the frequency rate or extent of transcription from an RNA polymerase II promoter. | www.broad.mit.e... |
Broad TRANSLATION | View Gene Set | 0.0001348 | 177 | 0.002852 | 39 | Genes annotated by the GO term GO:0006412. The chemical reactions and pathways resulting in the formation of a protein. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. | www.broad.mit.e... |
Broad CHROMOSOME_SEGREGATION | View Gene Set | 0.0001494 | 31 | 0.003081 | 40 | Genes annotated by the GO term GO:0007059. The process by which genetic material in the form of chromosomes is organized and then physically separated and apportioned to two or more sets. | www.broad.mit.e... |
Broad REGULATION_OF_VIRAL_REPRODUCTION | View Gene Set | 0.0002052 | 12 | 0.004128 | 41 | Genes annotated by the GO term GO:0050792. Any process that modulates the rate or extent of the viral life cycle the set of processes by which a virus reproduces and spreads among hosts. | www.broad.mit.e... |
Broad REGULATION_OF_MITOSIS | View Gene Set | 0.0002215 | 40 | 0.004351 | 42 | Genes annotated by the GO term GO:0007088. Any process that modulates the frequency rate or extent of mitosis. | www.broad.mit.e... |
Broad MRNA_PROCESSING_GO_0006397 | View Gene Set | 0.0002335 | 59 | 0.004481 | 43 | Genes annotated by the GO term GO:0006397. Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. | www.broad.mit.e... |
Broad RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY | View Gene Set | 0.0003117 | 74 | 0.005845 | 44 | Genes annotated by the GO term GO:0022613. The cellular process by which a complex containing RNA and proteins is synthesized aggregates and bonds together. | www.broad.mit.e... |
Broad ANDROGEN_RECEPTOR_SIGNALING_PATHWAY | View Gene Set | 0.0003371 | 12 | 0.006179 | 45 | Genes annotated by the GO term GO:0030521. Any series of molecular signals generated as a consequence of an androgen binding to its receptor. | www.broad.mit.e... |
Broad PROTEIN_RNA_COMPLEX_ASSEMBLY | View Gene Set | 0.0003563 | 59 | 0.00639 | 46 | Genes annotated by the GO term GO:0022618. The aggregation arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. | www.broad.mit.e... |
Broad PROTEIN_DNA_COMPLEX_ASSEMBLY | View Gene Set | 0.00041 | 48 | 0.007197 | 47 | Genes annotated by the GO term GO:0065004. The aggregation arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex. | www.broad.mit.e... |
Broad TRANSCRIPTION_INITIATION | View Gene Set | 0.0004716 | 35 | 0.008106 | 48 | Genes annotated by the GO term GO:0006352. Processes involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template resulting in the subsequent synthesis of RNA from that promoter. | www.broad.mit.e... |
Broad TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER | View Gene Set | 0.0005102 | 29 | 0.008591 | 49 | Genes annotated by the GO term GO:0006367. Processes involved in starting transcription from the RNA polymerase II promoter. | www.broad.mit.e... |
Broad CHROMATIN_REMODELING | View Gene Set | 0.0005587 | 23 | 0.009218 | 50 | Genes annotated by the GO term GO:0006338. Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. | www.broad.mit.e... |
Broad MRNA_SPLICE_SITE_SELECTION | View Gene Set | 0.0007688 | 6 | 0.01244 | 51 | Genes annotated by the GO term GO:0006376. Selection of a splice site by components of the assembling spliceosome. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS | View Gene Set | 0.0009852 | 252 | 0.01478 | 52 | Genes annotated by the GO term GO:0031324. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. | www.broad.mit.e... |
Broad STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | View Gene Set | 0.0009819 | 20 | 0.01478 | 52 | Genes annotated by the GO term GO:0030518. Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor. | www.broad.mit.e... |
Broad DNA_REPLICATION | View Gene Set | 0.000968 | 101 | 0.01478 | 52 | Genes annotated by the GO term GO:0006260. The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. | www.broad.mit.e... |
Broad INTRACELLULAR_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | View Gene Set | 0.0009819 | 21 | 0.01478 | 52 | Genes annotated by the GO term GO:0030522. Any series of molecular signals initiated by a ligand entering the target cell where it binds to an intracellular receptor. | www.broad.mit.e... |
Broad RESPONSE_TO_ENDOGENOUS_STIMULUS | View Gene Set | 0.001094 | 197 | 0.01556 | 56 | Genes annotated by the GO term GO:0009719. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of an endogenous stimulus. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_METABOLIC_PROCESS | View Gene Set | 0.001091 | 255 | 0.01556 | 56 | Genes annotated by the GO term GO:0009892. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways within a cell or an organism. | www.broad.mit.e... |
Broad CHROMATIN_MODIFICATION | View Gene Set | 0.00106 | 50 | 0.01556 | 56 | Genes annotated by the GO term GO:0016568. The alteration of DNA or protein in chromatin which may result in changing the chromatin structure. | www.broad.mit.e... |
Broad REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | View Gene Set | 0.001176 | 30 | 0.01644 | 59 | Genes annotated by the GO term GO:0040029. Any process that modulates the frequency rate or extent of gene expression; the process is mitotically or meiotically heritable or is stably self-propagated in the cytoplasm of a resting cell and does not entail a change in DNA sequence. | www.broad.mit.e... |
Broad DNA_RECOMBINATION | View Gene Set | 0.001241 | 47 | 0.01707 | 60 | Genes annotated by the GO term GO:0006310. The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment intrachromosomal recombination or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation conjugation transduction or F-duction. | www.broad.mit.e... |
Broad TRNA_METABOLIC_PROCESS | View Gene Set | 0.001279 | 18 | 0.01729 | 61 | Genes annotated by the GO term GO:0006399. The chemical reactions and pathways involving tRNA transfer RNA a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases the function of which has not been completely established. | www.broad.mit.e... |
Broad MRNA_METABOLIC_PROCESS | View Gene Set | 0.001325 | 70 | 0.01764 | 62 | Genes annotated by the GO term GO:0016071. The chemical reactions and pathways involving mRNA messenger RNA which is responsible for carrying the coded genetic 'message' transcribed from DNA to sites of protein assembly at the ribosomes. | www.broad.mit.e... |
Broad DOUBLE_STRAND_BREAK_REPAIR | View Gene Set | 0.001566 | 22 | 0.02051 | 63 | Genes annotated by the GO term GO:0006302. The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. | www.broad.mit.e... |
Broad MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | View Gene Set | 0.002439 | 34 | 0.03144 | 64 | Genes annotated by the GO term GO:0000226. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. | www.broad.mit.e... |
Broad RNA_SPLICINGVIA_TRANSESTERIFICATION_REACTIONS | View Gene Set | 0.003292 | 27 | 0.04179 | 65 | Genes annotated by the GO term GO:0000375. Splicing of RNA via a series of two transesterification reactions. | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad NUCLEUS | View Gene Set | 5.138e-25 | 1353 | 1.197e-22 | 1 | Genes annotated by the GO term GO:0005634. A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells the nucleus contains all of the cell's chromosomes except the organellar chromosomes and is the site of RNA synthesis and processing. In some species or in specialized cell types RNA metabolism or DNA replication may be absent. | www.broad.mit.e... |
Broad NUCLEAR_PART | View Gene Set | 2.891e-19 | 543 | 3.368e-17 | 2 | Genes annotated by the GO term GO:0044428. Any constituent part of the nucleus a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. | www.broad.mit.e... |
Broad RIBONUCLEOPROTEIN_COMPLEX | View Gene Set | 7.211e-13 | 129 | 5.601e-11 | 3 | Genes annotated by the GO term GO:0030529. A macromolecular complex containing both protein and RNA molecules. | www.broad.mit.e... |
Broad INTRACELLULAR_ORGANELLE_PART | View Gene Set | 4.259e-11 | 1144 | 2.481e-09 | 4 | Genes annotated by the GO term GO:0044446. A constituent part of an intracellular organelle an organized structure of distinctive morphology and function occurring within the cell. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. | www.broad.mit.e... |
Broad CHROMOSOMAL_PART | View Gene Set | 6.532e-11 | 95 | 3.044e-09 | 5 | Genes annotated by the GO term GO:0044427. Any constituent part of a chromosome a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. | www.broad.mit.e... |
Broad ORGANELLE_PART | View Gene Set | 9.513e-11 | 1149 | 3.318e-09 | 6 | Genes annotated by the GO term GO:0044422. Any constituent part of an organelle an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. | www.broad.mit.e... |
Broad CHROMOSOME | View Gene Set | 9.968e-11 | 122 | 3.318e-09 | 6 | Genes annotated by the GO term GO:0005694. A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. | www.broad.mit.e... |
Broad ORGANELLE_LUMEN | View Gene Set | 8.266e-10 | 434 | 2.14e-08 | 8 | Genes annotated by the GO term GO:0043233. The volume enclosed by the membranes of a particular organelle e.g. endoplasmic reticulum lumen or the space between the two lipid bilayers of a double membrane surrounding an organelle e.g. nuclear membrane lumen. | www.broad.mit.e... |
Broad MEMBRANE_ENCLOSED_LUMEN | View Gene Set | 8.266e-10 | 434 | 2.14e-08 | 8 | Genes annotated by the GO term GO:0031974. The enclosed volume within a sealed membrane or between two sealed membranes. | www.broad.mit.e... |
Broad MACROMOLECULAR_COMPLEX | View Gene Set | 1.68e-09 | 914 | 3.915e-08 | 10 | Genes annotated by the GO term GO:0032991. A stable assembly of two or more macromolecules i.e. proteins nucleic acids carbohydrates or lipids in which the constituent parts function together. | www.broad.mit.e... |
Broad CHROMOSOMEPERICENTRIC_REGION | View Gene Set | 9.902e-09 | 31 | 2.097e-07 | 11 | Genes annotated by the GO term GO:0000775. The central region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes this region corresponds to a single area of the chromosome whereas in holocentric chromosomes it is evenly distributed along the chromosome. | www.broad.mit.e... |
Broad NUCLEAR_LUMEN | View Gene Set | 1.43e-08 | 365 | 2.777e-07 | 12 | Genes annotated by the GO term GO:0031981. The volume enclosed by the nuclear inner membrane. | www.broad.mit.e... |
Broad SPLICEOSOME | View Gene Set | 1.943e-07 | 44 | 3.482e-06 | 13 | Genes annotated by the GO term GO:0005681. A ribonucleoprotein complex containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron. | www.broad.mit.e... |
Broad KINETOCHORE | View Gene Set | 1.085e-06 | 25 | 1.806e-05 | 14 | Genes annotated by the GO term GO:0000776. A multisubunit complex that is located at the pericentric region of DNA and provides an attachment point for the spindle microtubules. | www.broad.mit.e... |
Broad NUCLEOPLASM | View Gene Set | 3.037e-06 | 266 | 4.718e-05 | 15 | Genes annotated by the GO term GO:0005654. That part of the nuclear content other than the chromosomes or the nucleolus. | www.broad.mit.e... |
Broad SPINDLE_MICROTUBULE | View Gene Set | 4.28e-06 | 15 | 6.232e-05 | 16 | Genes annotated by the GO term GO:0005876. Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. | www.broad.mit.e... |
Broad CHROMATIN | View Gene Set | 2.278e-05 | 35 | 0.0003014 | 17 | Genes annotated by the GO term GO:0000785. The ordered and organized complex of DNA and protein that forms the chromosome. | www.broad.mit.e... |
Broad NUCLEOLUS | View Gene Set | 2.328e-05 | 116 | 0.0003014 | 17 | Genes annotated by the GO term GO:0005730. A small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA the processing of this RNA into 5.8S 18S and 28S components of ribosomal RNA and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. | www.broad.mit.e... |
Broad SPINDLE | View Gene Set | 3.672e-05 | 37 | 0.0004503 | 19 | Genes annotated by the GO term GO:0005819. The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. | www.broad.mit.e... |
Broad PROTEASOME_COMPLEX | View Gene Set | 4.688e-05 | 23 | 0.0005462 | 20 | Genes annotated by the GO term GO:0000502. A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. | www.broad.mit.e... |
Broad SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX | View Gene Set | 5.839e-05 | 20 | 0.0006479 | 21 | Genes annotated by the GO term GO:0030532. A complex composed of RNA of the small nuclear RNA (snRNA) class and protein found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain e.g. U1 snRNP or U4/U6 snRNP. Many but not all of these complexes are involved in splicing of nuclear mRNAs. | www.broad.mit.e... |
Broad ORGANELLAR_RIBOSOME | View Gene Set | 6.897e-05 | 22 | 0.0006987 | 22 | Genes annotated by the GO term GO:0000313. A ribosome contained within a subcellular organelle. | www.broad.mit.e... |
Broad MITOCHONDRIAL_RIBOSOME | View Gene Set | 6.897e-05 | 22 | 0.0006987 | 22 | Genes annotated by the GO term GO:0005761. A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. | www.broad.mit.e... |
Broad ENVELOPE | View Gene Set | 7.514e-05 | 165 | 0.0007003 | 24 | Genes annotated by the GO term GO:0031975. A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers and may include a cell wall layer also includes the space between layers. | www.broad.mit.e... |
Broad ORGANELLE_ENVELOPE | View Gene Set | 7.514e-05 | 165 | 0.0007003 | 24 | Genes annotated by the GO term GO:0031967. A double membrane structure enclosing an organelle including two lipid bilayers and the region between them. In some cases an organelle envelope may have more than two membranes. | www.broad.mit.e... |
Broad PROTEIN_COMPLEX | View Gene Set | 0.0001226 | 799 | 0.001099 | 26 | Genes annotated by the GO term GO:0043234. Any protein group composed of two or more subunits which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. | www.broad.mit.e... |
Broad RIBOSOME | View Gene Set | 0.0001513 | 39 | 0.001305 | 27 | Genes annotated by the GO term GO:0005840. An intracellular organelle about 200 A in diameter consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits one large and one small each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients expressed in Svedberg units (symbol: S). Hence the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes eukaryotes mitochondria and chloroplasts have characteristically distinct ribosomal proteins. | www.broad.mit.e... |
Broad NUCLEOPLASM_PART | View Gene Set | 0.0001778 | 202 | 0.00148 | 28 | Genes annotated by the GO term GO:0044451. Any constituent part of the nucleoplasm that part of the nuclear content other than the chromosomes or the nucleolus. | www.broad.mit.e... |
Broad RIBOSOMAL_SUBUNIT | View Gene Set | 0.0002009 | 20 | 0.001615 | 29 | Genes annotated by the GO term GO:0033279. Either of the two ribonucleoprotein complexes that associate to form a ribosome. | www.broad.mit.e... |
Broad CENTROSOME | View Gene Set | 0.000265 | 55 | 0.002058 | 30 | Genes annotated by the GO term GO:0005813. A structure comprised of a core structure (in most organisms a pair of centrioles) and peripheral material from which a microtubule-based structure such as a spindle apparatus is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells though in animal cells it changes continually during the cell-division cycle. | www.broad.mit.e... |
Broad NUCLEAR_CHROMOSOME | View Gene Set | 0.0002821 | 53 | 0.00212 | 31 | Genes annotated by the GO term GO:0000228. A chromosome found in the nucleus of a eukaryotic cell. | www.broad.mit.e... |
Broad ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT | View Gene Set | 0.0003857 | 11 | 0.002643 | 32 | Genes annotated by the GO term GO:0000314. The smaller of the two subunits of an organellar ribosome. | www.broad.mit.e... |
Broad MITOCHONDRIAL_SMALL_RIBOSOMAL_SUBUNIT | View Gene Set | 0.0003857 | 11 | 0.002643 | 32 | Genes annotated by the GO term GO:0005763. The smaller of the two subunits of a mitochondrial ribosome. | www.broad.mit.e... |
Broad SMALL_RIBOSOMAL_SUBUNIT | View Gene Set | 0.0003857 | 11 | 0.002643 | 32 | Genes annotated by the GO term GO:0015935. The smaller of the two subunits of a ribosome. | www.broad.mit.e... |
Broad MITOCHONDRIAL_PART | View Gene Set | 0.0004326 | 140 | 0.0028 | 35 | Genes annotated by the GO term GO:0044429. Any constituent part of a mitochondrion a semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. | www.broad.mit.e... |
Broad CONDENSED_CHROMOSOME | View Gene Set | 0.0004247 | 32 | 0.0028 | 35 | Genes annotated by the GO term GO:0000793. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. | www.broad.mit.e... |
Broad MICROTUBULE_ORGANIZING_CENTER | View Gene Set | 0.0007145 | 64 | 0.0045 | 37 | Genes annotated by the GO term GO:0005815. A region in a eukaryotic cell such as a centrosome or basal body from which microtubules grow. | www.broad.mit.e... |
Broad HETEROGENEOUS_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX | View Gene Set | 0.001226 | 9 | 0.007515 | 38 | Genes annotated by the GO term GO:0030530. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II that which is translated into protein) with protein which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA. | www.broad.mit.e... |
Broad NUCLEAR_PORE | View Gene Set | 0.00134 | 29 | 0.008007 | 39 | Genes annotated by the GO term GO:0005643. Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell where the inner and outer nuclear membranes are joined. | www.broad.mit.e... |
Broad DNA_DIRECTED_RNA_POLYMERASEII_HOLOENZYME | View Gene Set | 0.001375 | 65 | 0.008007 | 40 | Genes annotated by the GO term GO:0016591. Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA D E F and H which are required for promoter recognition and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA. | www.broad.mit.e... |
Broad MITOCHONDRIAL_MEMBRANE | View Gene Set | 0.001585 | 85 | 0.009009 | 41 | Genes annotated by the GO term GO:0031966. Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. | www.broad.mit.e... |
Broad MITOCHONDRIAL_INNER_MEMBRANE | View Gene Set | 0.002116 | 66 | 0.01174 | 42 | Genes annotated by the GO term GO:0005743. The inner i.e. lumen-facing lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. | www.broad.mit.e... |
Broad NUCLEAR_CHROMATIN | View Gene Set | 0.002623 | 14 | 0.01421 | 43 | Genes annotated by the GO term GO:0000790. The ordered and organized complex of DNA and protein that forms the chromosome in the nucleus. | www.broad.mit.e... |
Broad MITOCHONDRION | View Gene Set | 0.002782 | 335 | 0.01473 | 44 | Genes annotated by the GO term GO:0005739. A semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. | www.broad.mit.e... |
Broad TRANSCRIPTION_FACTOR_TFIID_COMPLEX | View Gene Set | 0.002909 | 14 | 0.01506 | 45 | Genes annotated by the GO term GO:0005669. A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II) TFIID is believed to recognize at least two distinct elements the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters. | www.broad.mit.e... |
Broad NUCLEAR_BODY | View Gene Set | 0.003143 | 31 | 0.01592 | 46 | Genes annotated by the GO term GO:0016604. Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. | www.broad.mit.e... |
Broad ORGANELLE_INNER_MEMBRANE | View Gene Set | 0.003372 | 74 | 0.01656 | 47 | Genes annotated by the GO term GO:0019866. The inner i.e. lumen-facing lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites. | www.broad.mit.e... |
Broad PORE_COMPLEX | View Gene Set | 0.003411 | 34 | 0.01656 | 47 | Genes annotated by the GO term GO:0046930. Any small opening in a membrane that allows the passage of gases and/or liquids. | www.broad.mit.e... |
Broad NON_MEMBRANE_BOUND_ORGANELLE | View Gene Set | 0.00374 | 613 | 0.01743 | 49 | Genes annotated by the GO term GO:0043228. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane. Includes ribosomes the cytoskeleton and chromosomes. | www.broad.mit.e... |
Broad INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE | View Gene Set | 0.00374 | 613 | 0.01743 | 49 | Genes annotated by the GO term GO:0043232. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes the cytoskeleton and chromosomes. | www.broad.mit.e... |
Broad MITOCHONDRIAL_ENVELOPE | View Gene Set | 0.004322 | 95 | 0.01974 | 51 | Genes annotated by the GO term GO:0005740. The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space. | www.broad.mit.e... |
Broad EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX | View Gene Set | 0.004743 | 10 | 0.02104 | 52 | Genes annotated by the GO term GO:0005852. A complex of several polypeptides that plays at least two important roles in protein synthesis: First eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. | www.broad.mit.e... |
Broad MITOCHONDRIAL_MEMBRANE_PART | View Gene Set | 0.004786 | 52 | 0.02104 | 52 | Genes annotated by the GO term GO:0044455. Any constituent part of the mitochondrial membrane either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. | www.broad.mit.e... |
Broad TRANSCRIPTION_FACTOR_COMPLEX | View Gene Set | 0.006342 | 84 | 0.02737 | 54 | Genes annotated by the GO term GO:0005667. Any complex distinct from RNA polymerase including one or more polypeptides capable of binding DNA at promoters or at cis-acting regulatory sequences and regulating transcription. | www.broad.mit.e... |
Broad NUCLEAR_ENVELOPE | View Gene Set | 0.00667 | 71 | 0.02826 | 55 | Genes annotated by the GO term GO:0005635. The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space a gap of width 20-40 nm (also called the perinuclear space). | www.broad.mit.e... |
Broad NUCLEAR_MEMBRANE | View Gene Set | 0.007872 | 48 | 0.03275 | 56 | Genes annotated by the GO term GO:0031965. Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. | www.broad.mit.e... |
Broad NUCLEAR_CHROMOSOME_PART | View Gene Set | 0.009298 | 33 | 0.03801 | 57 | Genes annotated by the GO term GO:0044454. Any constituent part of a nuclear chromosome a chromosome found in the nucleus of a eukaryotic cell. | www.broad.mit.e... |
Broad U12_DEPENDENT_SPLICEOSOME | View Gene Set | 0.009495 | 7 | 0.03814 | 58 | Genes annotated by the GO term GO:0005689. The minor (U12-dependent) spliceosome is composed of the snRNPs U11 U12 U4atac U6atac and U5 (which is also a component of the major spliceosome). This minor form of the spliceosome is responsible for the splicing of the majority of introns with atypical AT-AC terminal dinucleotides as well as other non-canonical introns. The entire splice site signal not just the terminal dinucleotides is involved in determining which spliceosome utilizes the site. | www.broad.mit.e... |
Broad MEDIATOR_COMPLEX | View Gene Set | 0.01096 | 18 | 0.0433 | 59 | Genes annotated by the GO term GO:0000119. A protein complex that enables the RNA polymerase II-general RNA polymerase II transcription factor complex to react to transcriptional activator proteins; also enhances the level of basal transcription. | www.broad.mit.e... |
Broad NUCLEAR_UBIQUITIN_LIGASE_COMPLEX | View Gene Set | 0.01156 | 11 | 0.04488 | 60 | Genes annotated by the GO term GO:0000152. A ubiquitin ligase complex found in the nucleus. | www.broad.mit.e... |
Broad NADH_DEHYDROGENASE_COMPLEX | View Gene Set | 0.01329 | 15 | 0.04915 | 61 | Genes annotated by the GO term GO:0030964. An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyses the transfer of a pair of electrons from NADH to a quinone. | www.broad.mit.e... |
Broad MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I | View Gene Set | 0.01329 | 15 | 0.04915 | 61 | Genes annotated by the GO term GO:0005747. A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits including NADH dehydrogenase (ubiquinone) flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III) and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. | www.broad.mit.e... |
Broad RESPIRATORY_CHAIN_COMPLEX_I | View Gene Set | 0.01329 | 15 | 0.04915 | 61 | Genes annotated by the GO term GO:0045271. Respiratory chain complex I is an enzyme of the respiratory chain. It consists of at least 34 polypeptide chains and is L-shaped with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex. | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad RNA_BINDING | View Gene Set | 1.841e-11 | 236 | 7.292e-09 | 1 | Genes annotated by the GO term GO:0003723. Interacting selectively with an RNA molecule or a portion thereof. | www.broad.mit.e... |
Broad DNA_BINDING | View Gene Set | 5.648e-07 | 587 | 0.0001118 | 2 | Genes annotated by the GO term GO:0003677. Interacting selectively with DNA (deoxyribonucleic acid). | www.broad.mit.e... |
Broad STRUCTURE_SPECIFIC_DNA_BINDING | View Gene Set | 4.261e-06 | 55 | 0.0004263 | 3 | Genes annotated by the GO term GO:0043566. Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. | www.broad.mit.e... |
Broad TRANSCRIPTION_FACTOR_BINDING | View Gene Set | 6.459e-06 | 300 | 0.0004263 | 3 | Genes annotated by the GO term GO:0008134. Interacting selectively with a transcription factor any protein required to initiate or regulate transcription. | www.broad.mit.e... |
Broad HORMONE_RECEPTOR_BINDING | View Gene Set | 4.683e-06 | 29 | 0.0004263 | 3 | Genes annotated by the GO term GO:0051427. Interacting selectively with a receptor for hormones. | www.broad.mit.e... |
Broad TRANSCRIPTION_COFACTOR_ACTIVITY | View Gene Set | 5.447e-06 | 222 | 0.0004263 | 3 | Genes annotated by the GO term GO:0003712. The function that links a sequence-specific transcription factor to the core RNA polymerase II complex but does not bind DNA itself. | www.broad.mit.e... |
Broad NUCLEAR_HORMONE_RECEPTOR_BINDING | View Gene Set | 8.132e-06 | 28 | 0.0004601 | 7 | Genes annotated by the GO term GO:0035257. Interacting selectively with a nuclear hormone receptor a ligand-dependent receptor found in the nucleus of the cell. | www.broad.mit.e... |
Broad RNA_SPLICING_FACTOR_ACTIVITYTRANSESTERIFICATION_MECHANISM | View Gene Set | 1.261e-05 | 14 | 0.0005548 | 8 | Genes annotated by the GO term GO:0031202. An activity which binds RNA and functions to assist splicing of substrate RNA(s) by facilitating the formation and stabilization of a catalytic conformation in which the splice junctions of the RNA(s) to be spliced are positioned for a transesterification reaction that occurs between two sites within the RNA(s) to be spliced. | www.broad.mit.e... |
Broad TRANSCRIPTION_ACTIVATOR_ACTIVITY | View Gene Set | 1.159e-05 | 169 | 0.0005548 | 8 | Genes annotated by the GO term GO:0016563. Any transcription regulator activity required for initiation or upregulation of transcription. | www.broad.mit.e... |
Broad CHROMATIN_BINDING | View Gene Set | 2.213e-05 | 32 | 0.0008762 | 10 | Genes annotated by the GO term GO:0003682. Interacting selectively with chromatin the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. | www.broad.mit.e... |
Broad TRANSCRIPTION_COACTIVATOR_ACTIVITY | View Gene Set | 2.452e-05 | 121 | 0.0008828 | 11 | Genes annotated by the GO term GO:0003713. The function of a transcription cofactor that activates transcription from a RNA polymerase II promoter; does not bind DNA itself. | www.broad.mit.e... |
Broad SINGLE_STRANDED_DNA_BINDING | View Gene Set | 3.52e-05 | 34 | 0.001072 | 12 | Genes annotated by the GO term GO:0003697. Interacting selectively with single-stranded DNA. | www.broad.mit.e... |
Broad STEROID_HORMONE_RECEPTOR_BINDING | View Gene Set | 3.28e-05 | 10 | 0.001072 | 12 | Genes annotated by the GO term GO:0035258. Interacting selectively with a steroid hormone receptor. | www.broad.mit.e... |
Broad DOUBLE_STRANDED_DNA_BINDING | View Gene Set | 6.709e-05 | 32 | 0.001898 | 14 | Genes annotated by the GO term GO:0003690. Interacting selectively with double-stranded DNA. | www.broad.mit.e... |
Broad N_METHYLTRANSFERASE_ACTIVITY | View Gene Set | 0.0003979 | 13 | 0.01051 | 15 | Genes annotated by the GO term GO:0008170. Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. | www.broad.mit.e... |
Broad RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY | View Gene Set | 0.0005062 | 182 | 0.01114 | 16 | Genes annotated by the GO term GO:0003702. Functions to initiate or regulate RNA polymerase II transcription. | www.broad.mit.e... |
Broad THYROID_HORMONE_RECEPTOR_BINDING | View Gene Set | 0.0005063 | 17 | 0.01114 | 16 | Genes annotated by the GO term GO:0046966. Interacting selectively with a thyroid hormone receptor. | www.broad.mit.e... |
Broad GENERAL_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY | View Gene Set | 0.0004566 | 32 | 0.01114 | 16 | Genes annotated by the GO term GO:0016251. Any function that supports basal (unregulated) transcription of genes by core RNA polymerase II. Five general transcription factors are necessary and sufficient for such basal transcription in yeast: TFIIB TFIID TFIIE TFIIF TFIIH and TATA-binding protein (TBF). | www.broad.mit.e... |
Broad HISTONE_METHYLTRANSFERASE_ACTIVITY | View Gene Set | 0.0006366 | 11 | 0.01327 | 19 | Genes annotated by the GO term GO:0042054. Catalysis of the transfer of a methyl group (CH3-) to a histone. | www.broad.mit.e... |
Broad RNA_HELICASE_ACTIVITY | View Gene Set | 0.001536 | 24 | 0.03041 | 20 | Genes annotated by the GO term GO:0003724. Catalysis of the unwinding of an RNA helix. | www.broad.mit.e... |
Broad ENDONUCLEASE_ACTIVITY_GO_0016893 | View Gene Set | 0.001709 | 11 | 0.03223 | 21 | Genes annotated by the GO term GO:0016893. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. | www.broad.mit.e... |
Broad RNA_DEPENDENT_ATPASE_ACTIVITY | View Gene Set | 0.00206 | 18 | 0.03708 | 22 | Genes annotated by the GO term GO:0008186. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of RNA; drives another reaction. | www.broad.mit.e... |
Broad ENDORIBONUCLEASE_ACTIVITY | View Gene Set | 0.0022 | 13 | 0.03788 | 23 | Genes annotated by the GO term GO:0004521. Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. | www.broad.mit.e... |
Broad LIGASE_ACTIVITY_FORMING_CARBON_NITROGEN_BONDS | View Gene Set | 0.002756 | 68 | 0.04366 | 24 | Genes annotated by the GO term GO:0016879. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. | www.broad.mit.e... |
Broad METHYLTRANSFERASE_ACTIVITY | View Gene Set | 0.002704 | 36 | 0.04366 | 24 | Genes annotated by the GO term GO:0008168. Catalysis of the transfer of a methyl group to an acceptor molecule. | www.broad.mit.e... |
Broad LIGASE_ACTIVITY | View Gene Set | 0.003148 | 97 | 0.04426 | 26 | Genes annotated by the GO term GO:0016874. Catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. | www.broad.mit.e... |
Broad RIBONUCLEASE_ACTIVITY | View Gene Set | 0.003137 | 25 | 0.04426 | 26 | Genes annotated by the GO term GO:0004540. Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. | www.broad.mit.e... |
Broad TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING | View Gene Set | 0.003096 | 39 | 0.04426 | 26 | Genes annotated by the GO term GO:0008135. Functions during translation by binding nucleic acids during polypeptide synthesis at the ribosome. | www.broad.mit.e... |
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS | View Gene Set | 0.003241 | 37 | 0.04426 | 26 | Genes annotated by the GO term GO:0016741. Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor). | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
PMID 15302935 | View Gene Set | 1.152e-21 | 773 | 2.889e-18 | 1 | Large-scale characterization of HeLa cell nuclear phosphoproteins. | www.ncbi.nlm.ni... |
PMID 15635413 | View Gene Set | 3.668e-19 | 421 | 4.598e-16 | 2 | Nucleolar proteome dynamics. | www.ncbi.nlm.ni... |
PMID 17643375 | View Gene Set | 6.734e-19 | 391 | 5.628e-16 | 3 | Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. | www.ncbi.nlm.ni... |
PMID 12226669 | View Gene Set | 6.518e-15 | 108 | 4.085e-12 | 4 | Comprehensive proteomic analysis of the human spliceosome. | www.ncbi.nlm.ni... |
PMID 11991638 | View Gene Set | 7.899e-13 | 74 | 3.301e-10 | 5 | Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. | www.ncbi.nlm.ni... |
PMID 16964243 | View Gene Set | 7.792e-13 | 504 | 3.301e-10 | 5 | A probability-based approach for high-throughput protein phosphorylation analysis and site localization. | www.ncbi.nlm.ni... |
PMID 12706105 | View Gene Set | 4.019e-12 | 182 | 1.439e-09 | 7 | Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. | www.ncbi.nlm.ni... |
PMID 11790298 | View Gene Set | 2.57e-10 | 208 | 8.053e-08 | 8 | Directed proteomic analysis of the human nucleolus. | www.ncbi.nlm.ni... |
PMID 11543634 | View Gene Set | 7.434e-09 | 58 | 1.949e-06 | 9 | The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. | www.ncbi.nlm.ni... |
PMID 9731529 | View Gene Set | 7.776e-09 | 24 | 1.949e-06 | 9 | Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. | www.ncbi.nlm.ni... |
PMID 16565220 | View Gene Set | 1.404e-08 | 210 | 3.2e-06 | 11 | Phosphoproteome analysis of the human mitotic spindle. | www.ncbi.nlm.ni... |
PMID 12429849 | View Gene Set | 2.198e-08 | 106 | 4.592e-06 | 12 | Functional proteomic analysis of human nucleolus. | www.ncbi.nlm.ni... |
PMID 14559993 | View Gene Set | 2.595e-08 | 51 | 5.004e-06 | 13 | Regulation of alternative splicing by SRrp86 and its interacting proteins. | www.ncbi.nlm.ni... |
PMID 11285280 | View Gene Set | 2.849e-08 | 62 | 5.102e-06 | 14 | Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. | www.ncbi.nlm.ni... |
PMID 15231747 | View Gene Set | 2.279e-07 | 212 | 3.809e-05 | 15 | A protein interaction framework for human mRNA degradation. | www.ncbi.nlm.ni... |
PMID 12234937 | View Gene Set | 6.439e-07 | 34 | 0.0001009 | 16 | Characterization of novel SF3b and 17S U2 snRNP proteins including a human Prp5p homologue and an SF3b DEAD-box protein. | www.ncbi.nlm.ni... |
PMID 15029244 | View Gene Set | 7.424e-07 | 57 | 0.0001095 | 17 | Mammalian Cdh1/Fzr mediates its own degradation. | www.ncbi.nlm.ni... |
PMID 11279123 | View Gene Set | 8.896e-07 | 31 | 0.0001239 | 18 | The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. | www.ncbi.nlm.ni... |
PMID 15146077 | View Gene Set | 1.094e-06 | 32 | 0.0001443 | 19 | The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. | www.ncbi.nlm.ni... |
PMID 20508983 | View Gene Set | 1.756e-06 | 102 | 0.0002201 | 20 | Centrosome-related genes genetic variation and risk of breast cancer. | www.ncbi.nlm.ni... |
PMID 11076961 | View Gene Set | 3.293e-06 | 14 | 0.0003931 | 21 | Characterization of vertebrate cohesin complexes and their regulation in prophase. | www.ncbi.nlm.ni... |
PMID 10810093 | View Gene Set | 3.99e-06 | 151 | 0.0004546 | 22 | Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. | www.ncbi.nlm.ni... |
PMID 12791267 | View Gene Set | 4.342e-06 | 50 | 0.0004732 | 23 | Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. | www.ncbi.nlm.ni... |
PMID 14564014 | View Gene Set | 8.255e-06 | 47 | 0.0008623 | 24 | Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. | www.ncbi.nlm.ni... |
PMID 12837248 | View Gene Set | 9.859e-06 | 22 | 0.0009886 | 25 | The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. | www.ncbi.nlm.ni... |
PMID 15504738 | View Gene Set | 1.13e-05 | 19 | 0.001089 | 26 | Genes affecting the cell cycle growth maintenance and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. | www.ncbi.nlm.ni... |
PMID 17148452 | View Gene Set | 1.173e-05 | 87 | 0.001089 | 26 | Characterization of the interactome of the human MutL homologues MLH1 PMS1 and PMS2. | www.ncbi.nlm.ni... |
PMID 11042152 | View Gene Set | 1.272e-05 | 315 | 0.001104 | 28 | Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. | www.ncbi.nlm.ni... |
PMID 20516191 | View Gene Set | 1.277e-05 | 12 | 0.001104 | 28 | A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins). | www.ncbi.nlm.ni... |
PMID 12859895 | View Gene Set | 1.42e-05 | 47 | 0.00118 | 30 | Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. | www.ncbi.nlm.ni... |
PMID 18377426 | View Gene Set | 1.459e-05 | 20 | 0.00118 | 30 | Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex. | www.ncbi.nlm.ni... |
PMID 19710015 | View Gene Set | 1.592e-05 | 48 | 0.001247 | 32 | The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor. | www.ncbi.nlm.ni... |
PMID 20496165 | View Gene Set | 1.653e-05 | 68 | 0.001256 | 33 | Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. | www.ncbi.nlm.ni... |
PMID 8811196 | View Gene Set | 1.94e-05 | 37 | 0.001431 | 34 | Structure and functions of the 20S and 26S proteasomes. | www.ncbi.nlm.ni... |
PMID 11500380 | View Gene Set | 2.374e-05 | 10 | 0.001517 | 35 | A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. | www.ncbi.nlm.ni... |
PMID 11551941 | View Gene Set | 2.749e-05 | 26 | 0.001517 | 35 | The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. | www.ncbi.nlm.ni... |
PMID 12719574 | View Gene Set | 2.845e-05 | 42 | 0.001517 | 35 | Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions. | www.ncbi.nlm.ni... |
PMID 12750511 | View Gene Set | 2.845e-05 | 42 | 0.001517 | 35 | Hypermutation of HIV-1 DNA in the absence of the Vif protein. | www.ncbi.nlm.ni... |
PMID 12830140 | View Gene Set | 2.845e-05 | 42 | 0.001517 | 35 | DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses. | www.ncbi.nlm.ni... |
PMID 12840737 | View Gene Set | 2.845e-05 | 42 | 0.001517 | 35 | Good to CU. | www.ncbi.nlm.ni... |
PMID 12914693 | View Gene Set | 2.845e-05 | 42 | 0.001517 | 35 | Death by deamination: a novel host restriction system for HIV-1. | www.ncbi.nlm.ni... |
PMID 12920286 | View Gene Set | 2.845e-05 | 42 | 0.001517 | 35 | Virology. Weapons of mutational destruction. | www.ncbi.nlm.ni... |
PMID 14614829 | View Gene Set | 2.845e-05 | 42 | 0.001517 | 35 | The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G. | www.ncbi.nlm.ni... |
PMID 18162579 | View Gene Set | 2.461e-05 | 22 | 0.001517 | 35 | Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. | www.ncbi.nlm.ni... |
PMID 20085707 | View Gene Set | 2.125e-05 | 42 | 0.001517 | 35 | Aire's partners in the molecular control of immunological tolerance. | www.ncbi.nlm.ni... |
PMID 9811770 | View Gene Set | 2.845e-05 | 42 | 0.001517 | 35 | An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein. | www.ncbi.nlm.ni... |
PMID 9846577 | View Gene Set | 2.845e-05 | 42 | 0.001517 | 35 | Evidence for a newly discovered cellular anti-HIV-1 phenotype. | www.ncbi.nlm.ni... |
PMID 14667819 | View Gene Set | 2.912e-05 | 112 | 0.001521 | 48 | Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. | www.ncbi.nlm.ni... |
PMID 12167863 | View Gene Set | 3.883e-05 | 43 | 0.001708 | 49 | Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. | www.ncbi.nlm.ni... |
PMID 12808465 | View Gene Set | 3.883e-05 | 43 | 0.001708 | 49 | The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. | www.ncbi.nlm.ni... |
PMID 12808466 | View Gene Set | 3.883e-05 | 43 | 0.001708 | 49 | Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. | www.ncbi.nlm.ni... |
PMID 12809610 | View Gene Set | 3.883e-05 | 43 | 0.001708 | 49 | DNA deamination mediates innate immunity to retroviral infection. | www.ncbi.nlm.ni... |
PMID 12970355 | View Gene Set | 3.883e-05 | 43 | 0.001708 | 49 | The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity. | www.ncbi.nlm.ni... |
PMID 14527406 | View Gene Set | 3.883e-05 | 43 | 0.001708 | 49 | HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. | www.ncbi.nlm.ni... |
PMID 14528300 | View Gene Set | 3.883e-05 | 43 | 0.001708 | 49 | The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. | www.ncbi.nlm.ni... |
PMID 14528301 | View Gene Set | 3.883e-05 | 43 | 0.001708 | 49 | HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. | www.ncbi.nlm.ni... |
PMID 14557625 | View Gene Set | 3.883e-05 | 43 | 0.001708 | 49 | The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15) a cellular inhibitor of virus infectivity. | www.ncbi.nlm.ni... |
PMID 10893419 | View Gene Set | 4.226e-05 | 41 | 0.001737 | 58 | Degradation of HIV-1 integrase by the N-end rule pathway. | www.ncbi.nlm.ni... |
PMID 12419264 | View Gene Set | 4.226e-05 | 41 | 0.001737 | 58 | The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing. | www.ncbi.nlm.ni... |
PMID 14550573 | View Gene Set | 4.226e-05 | 41 | 0.001737 | 58 | Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits. | www.ncbi.nlm.ni... |
PMID 9079628 | View Gene Set | 4.226e-05 | 41 | 0.001737 | 58 | HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation. | www.ncbi.nlm.ni... |
PMID 19690177 | View Gene Set | 4.366e-05 | 31 | 0.001766 | 62 | Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk. | www.ncbi.nlm.ni... |
PMID 18997788 | View Gene Set | 4.628e-05 | 10 | 0.001842 | 63 | The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction. | www.ncbi.nlm.ni... |
PMID 9153318 | View Gene Set | 7.134e-05 | 11 | 0.002795 | 64 | CCAAT binding NF-Y-TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues. | www.ncbi.nlm.ni... |
PMID 10531003 | View Gene Set | 9.06e-05 | 15 | 0.003494 | 65 | Newly assembled snRNPs associate with coiled bodies before speckles suggesting a nuclear snRNP maturation pathway. | www.ncbi.nlm.ni... |
PMID 15502821 | View Gene Set | 0.0001186 | 12 | 0.004505 | 66 | A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. | www.ncbi.nlm.ni... |
PMID 18485873 | View Gene Set | 0.0001442 | 13 | 0.005395 | 67 | Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. | www.ncbi.nlm.ni... |
PMID 15456888 | View Gene Set | 0.0001748 | 24 | 0.006365 | 68 | The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. | www.ncbi.nlm.ni... |
PMID 19237606 | View Gene Set | 0.0001777 | 84 | 0.006365 | 68 | Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. | www.ncbi.nlm.ni... |
PMID 9472028 | View Gene Set | 0.0001771 | 12 | 0.006365 | 68 | SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. | www.ncbi.nlm.ni... |
PMID 11734557 | View Gene Set | 0.0001829 | 12 | 0.00637 | 71 | SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones. | www.ncbi.nlm.ni... |
PMID 19060904 | View Gene Set | 0.000183 | 130 | 0.00637 | 71 | An empirical framework for binary interactome mapping. | www.ncbi.nlm.ni... |
PMID 11748230 | View Gene Set | 0.0001866 | 17 | 0.006375 | 73 | Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. | www.ncbi.nlm.ni... |
PMID 15009096 | View Gene Set | 0.0001882 | 39 | 0.006375 | 73 | Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex while BMI-1 is transiently co-localized with the centromeric region in interphase. | www.ncbi.nlm.ni... |
PMID 14580349 | View Gene Set | 0.0001959 | 14 | 0.00655 | 75 | The TBN protein which is essential for early embryonic mouse development is an inducible TAFII implicated in adipogenesis. | www.ncbi.nlm.ni... |
PMID 11101529 | View Gene Set | 0.0002442 | 34 | 0.008055 | 76 | Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. | www.ncbi.nlm.ni... |
PMID 17363900 | View Gene Set | 0.0002503 | 14 | 0.008149 | 77 | The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. | www.ncbi.nlm.ni... |
PMID 20522537 | View Gene Set | 0.0002918 | 73 | 0.009378 | 78 | Variation within DNA repair pathway genes and risk of multiple sclerosis. | www.ncbi.nlm.ni... |
PMID 12601814 | View Gene Set | 0.0002974 | 12 | 0.009438 | 79 | Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis. | www.ncbi.nlm.ni... |
PMID 10793135 | View Gene Set | 0.0003123 | 18 | 0.009786 | 80 | Mitotic regulation of the APC activator proteins CDC20 and CDH1. | www.ncbi.nlm.ni... |
PMID 15778465 | View Gene Set | 0.0003176 | 91 | 0.00983 | 81 | Targeted proteomic analysis of 14-3-3 sigma a p53 effector commonly silenced in cancer. | www.ncbi.nlm.ni... |
PMID 11535616 | View Gene Set | 0.0003451 | 18 | 0.01042 | 82 | Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1 BUB3 CDC20 and MAD2. | www.ncbi.nlm.ni... |
PMID 14593737 | View Gene Set | 0.0003451 | 18 | 0.01042 | 82 | The mitotic checkpoint: a signaling pathway that allows a single unattached kinetochore to inhibit mitotic exit. | www.ncbi.nlm.ni... |
PMID 15130578 | View Gene Set | 0.0003614 | 22 | 0.01078 | 84 | Why do cells need an assembly machine for RNA-protein complexes? | www.ncbi.nlm.ni... |
PMID 12171929 | View Gene Set | 0.0004078 | 31 | 0.01203 | 85 | A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. | www.ncbi.nlm.ni... |
PMID 10983978 | View Gene Set | 0.0004436 | 10 | 0.01293 | 86 | Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. | www.ncbi.nlm.ni... |
PMID 19047128 | View Gene Set | 0.0004616 | 19 | 0.01315 | 87 | Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma. | www.ncbi.nlm.ni... |
PMID 19116388 | View Gene Set | 0.0004574 | 37 | 0.01315 | 87 | A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility. | www.ncbi.nlm.ni... |
PMID 11416179 | View Gene Set | 0.0004796 | 12 | 0.01351 | 89 | All kinesin superfamily protein KIF genes in mouse and human. | www.ncbi.nlm.ni... |
PMID 8724849 | View Gene Set | 0.000499 | 41 | 0.0139 | 90 | Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. | www.ncbi.nlm.ni... |
PMID 11078522 | View Gene Set | 0.0005186 | 12 | 0.01398 | 91 | The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. | www.ncbi.nlm.ni... |
PMID 11564863 | View Gene Set | 0.0005156 | 23 | 0.01398 | 91 | Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. | www.ncbi.nlm.ni... |
PMID 16364912 | View Gene Set | 0.0005158 | 12 | 0.01398 | 91 | Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. | www.ncbi.nlm.ni... |
PMID 19138993 | View Gene Set | 0.0005877 | 25 | 0.01567 | 94 | Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. | www.ncbi.nlm.ni... |
PMID 10725331 | View Gene Set | 0.0006073 | 14 | 0.0157 | 95 | Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. | www.ncbi.nlm.ni... |
PMID 11205743 | View Gene Set | 0.0006066 | 15 | 0.0157 | 95 | Polo-like kinase interacts with proteasomes and regulates their activity. | www.ncbi.nlm.ni... |
PMID 14638676 | View Gene Set | 0.0006025 | 28 | 0.0157 | 95 | A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2. | www.ncbi.nlm.ni... |
PMID 18826954 | View Gene Set | 0.0007059 | 10 | 0.01806 | 98 | SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation. | www.ncbi.nlm.ni... |
PMID 7933101 | View Gene Set | 0.0007369 | 17 | 0.01866 | 99 | Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function. | www.ncbi.nlm.ni... |
PMID 11402041 | View Gene Set | 0.0007609 | 16 | 0.01879 | 100 | Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28 S small subunit. | www.ncbi.nlm.ni... |
PMID 12388589 | View Gene Set | 0.000756 | 17 | 0.01879 | 100 | A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. | www.ncbi.nlm.ni... |
PMID 19596235 | View Gene Set | 0.0007643 | 85 | 0.01879 | 100 | Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. | www.ncbi.nlm.ni... |
PMID 10318877 | View Gene Set | 0.0008028 | 10 | 0.01936 | 103 | Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex. | www.ncbi.nlm.ni... |
PMID 11018012 | View Gene Set | 0.000803 | 11 | 0.01936 | 103 | Functional selectivity of recombinant mammalian SWI/SNF subunits. | www.ncbi.nlm.ni... |
PMID 15782174 | View Gene Set | 0.0008124 | 31 | 0.0194 | 105 | Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. | www.ncbi.nlm.ni... |
PMID 10069390 | View Gene Set | 0.0008362 | 10 | 0.01978 | 106 | Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases. | www.ncbi.nlm.ni... |
PMID 15647280 | View Gene Set | 0.00088 | 17 | 0.02062 | 107 | The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. | www.ncbi.nlm.ni... |
PMID 10851237 | View Gene Set | 0.0009242 | 11 | 0.02145 | 108 | Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). | www.ncbi.nlm.ni... |
PMID 11406595 | View Gene Set | 0.0009881 | 16 | 0.02273 | 109 | UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation. | www.ncbi.nlm.ni... |
PMID 16387653 | View Gene Set | 0.001381 | 42 | 0.03148 | 110 | ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. | www.ncbi.nlm.ni... |
PMID 17137291 | View Gene Set | 0.00146 | 10 | 0.03297 | 111 | Physical interaction of two cancer-testis antigens MAGE-C1 (CT7) and NY-ESO-1 (CT6). | www.ncbi.nlm.ni... |
PMID 12065586 | View Gene Set | 0.001582 | 14 | 0.03449 | 112 | Identification and characterization of Gemin7 a novel component of the survival of motor neuron complex. | www.ncbi.nlm.ni... |
PMID 15383276 | View Gene Set | 0.001578 | 67 | 0.03449 | 112 | A protein interaction network links GIT1 an enhancer of huntingtin aggregation to Huntington's disease. | www.ncbi.nlm.ni... |
PMID 18809582 | View Gene Set | 0.001562 | 25 | 0.03449 | 112 | Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. | www.ncbi.nlm.ni... |
PMID 8895581 | View Gene Set | 0.001567 | 12 | 0.03449 | 112 | Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. | www.ncbi.nlm.ni... |
PMID 14578343 | View Gene Set | 0.001648 | 19 | 0.03562 | 116 | Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains. | www.ncbi.nlm.ni... |
PMID 10922056 | View Gene Set | 0.001729 | 12 | 0.03705 | 117 | The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex. | www.ncbi.nlm.ni... |
PMID 15146197 | View Gene Set | 0.001744 | 693 | 0.03705 | 118 | Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. | www.ncbi.nlm.ni... |
PMID 11384984 | View Gene Set | 0.001864 | 12 | 0.03862 | 119 | Muf1 a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase. | www.ncbi.nlm.ni... |
PMID 11604498 | View Gene Set | 0.001895 | 12 | 0.03862 | 119 | The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1. | www.ncbi.nlm.ni... |
PMID 12956947 | View Gene Set | 0.00188 | 15 | 0.03862 | 119 | TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. | www.ncbi.nlm.ni... |
PMID 14743216 | View Gene Set | 0.001883 | 132 | 0.03862 | 119 | A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. | www.ncbi.nlm.ni... |
PMID 9822659 | View Gene Set | 0.001859 | 11 | 0.03862 | 119 | Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3. | www.ncbi.nlm.ni... |
PMID 14567916 | View Gene Set | 0.001992 | 50 | 0.04026 | 124 | Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. | www.ncbi.nlm.ni... |
PMID 17466952 | View Gene Set | 0.002026 | 11 | 0.04064 | 125 | Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways. | www.ncbi.nlm.ni... |
PMID 18701435 | View Gene Set | 0.002073 | 13 | 0.04125 | 126 | Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. | www.ncbi.nlm.ni... |
PMID 11714716 | View Gene Set | 0.002111 | 13 | 0.04168 | 127 | Gemin5 a novel WD repeat protein component of the SMN complex that binds Sm proteins. | www.ncbi.nlm.ni... |
PMID 12791985 | View Gene Set | 0.002354 | 37 | 0.04611 | 128 | Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. | www.ncbi.nlm.ni... |
PMID 15142377 | View Gene Set | 0.002579 | 19 | 0.04973 | 129 | Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1. | www.ncbi.nlm.ni... |
PMID 20232390 | View Gene Set | 0.002562 | 15 | 0.04973 | 129 | Genetic variations of DNA repair genes and their prognostic significance in patients with acute myeloid leukemia. | www.ncbi.nlm.ni... |
PMID 17478428 | View Gene Set | 0.002611 | 10 | 0.04996 | 131 | A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints. | www.ncbi.nlm.ni... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null PS50102 | View Gene Set | 4.845e-26 | 229 | 3.561e-23 | 1 | RRM | expasy.org/pros... |
Null PS50157 | View Gene Set | 2.428e-14 | 811 | 8.922e-12 | 2 | ZINC_FINGER_C2H2_2 | expasy.org/pros... |
Null PS00028 | View Gene Set | 4.599e-14 | 830 | 1.127e-11 | 3 | ZINC_FINGER_C2H2_1 | expasy.org/pros... |
Null PS50014 | View Gene Set | 5.691e-06 | 41 | 0.001046 | 4 | BROMODOMAIN_2 | expasy.org/pros... |
Null PS50805 | View Gene Set | 9.315e-06 | 415 | 0.001369 | 5 | KRAB | expasy.org/pros... |
Null PS51192 | View Gene Set | 2.985e-05 | 112 | 0.003134 | 6 | HELICASE_ATP_BIND_1 | expasy.org/pros... |
Null PS51194 | View Gene Set | 2.561e-05 | 113 | 0.003134 | 6 | HELICASE_CTER | expasy.org/pros... |
Null PS50051 | View Gene Set | 5.548e-05 | 8 | 0.005097 | 8 | MCM_2 | expasy.org/pros... |
Null PS00847 | View Gene Set | 0.0001774 | 6 | 0.01336 | 9 | MCM_1 | expasy.org/pros... |
Null PS51195 | View Gene Set | 0.0001817 | 37 | 0.01336 | 9 | Q_MOTIF | expasy.org/pros... |
Null PS50280 | View Gene Set | 0.0002326 | 47 | 0.01554 | 11 | SET | expasy.org/pros... |
Null PS50166 | View Gene Set | 0.0002737 | 13 | 0.01677 | 12 | IMPORTIN_B_NT | expasy.org/pros... |
Null PS00633 | View Gene Set | 0.0003091 | 26 | 0.01748 | 13 | BROMODOMAIN_1 | expasy.org/pros... |
Null PS50868 | View Gene Set | 0.0003786 | 16 | 0.01987 | 14 | POST_SET | expasy.org/pros... |
Null PS50171 | View Gene Set | 0.0004769 | 9 | 0.02337 | 15 | ZF_MATRIN | expasy.org/pros... |
Null PS50800 | View Gene Set | 0.0005926 | 23 | 0.02722 | 16 | SAP | expasy.org/pros... |
Null PS50172 | View Gene Set | 0.001093 | 21 | 0.04727 | 17 | BRCT | expasy.org/pros... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null EC:2.1.1.43 | View Gene Set | 3.561e-06 | 19 | 0.0005627 | 1 | Histone-lysine N-methyltransferase | expasy.org/enzy... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null ppi.CFLAR | View Gene Set | 9.483e-05 | 6 | 0.01792 | 1 | Protein-protein-interaction for CFLAR | www.ncbi.nlm.ni... |
Null ppi.1460853 | View Gene Set | 0.0003758 | 6 | 0.03551 | 2 | Protein-protein-interaction for 1460853 | www.ncbi.nlm.ni... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null ppi.155871 | View Gene Set | 7.147e-13 | 236 | 1.642e-09 | 1 | Protein-protein-interaction for 155871 | www.ncbi.nlm.ni... |
Null ppi.MEPCE | View Gene Set | 2.494e-12 | 147 | 2.865e-09 | 2 | Protein-protein-interaction for MEPCE | www.ncbi.nlm.ni... |
Null ppi.SRRM1 | View Gene Set | 3.808e-09 | 64 | 2.916e-06 | 3 | Protein-protein-interaction for SRRM1 | www.ncbi.nlm.ni... |
Null ppi.WBP4 | View Gene Set | 6.715e-09 | 35 | 3.856e-06 | 4 | Protein-protein-interaction for WBP4 | www.ncbi.nlm.ni... |
Null ppi.SRRM2 | View Gene Set | 9.842e-08 | 101 | 4.521e-05 | 5 | Protein-protein-interaction for SRRM2 | www.ncbi.nlm.ni... |
Null ppi.HIST1H4A | View Gene Set | 8.201e-07 | 28 | 0.000314 | 6 | Protein-protein-interaction for HIST1H4A | www.ncbi.nlm.ni... |
Null ppi.PRPF40A | View Gene Set | 2.756e-06 | 53 | 0.0009044 | 7 | Protein-protein-interaction for PRPF40A | www.ncbi.nlm.ni... |
Null ppi.KHDRBS2 | View Gene Set | 4.273e-06 | 46 | 0.00109 | 8 | Protein-protein-interaction for KHDRBS2 | www.ncbi.nlm.ni... |
Null ppi.UCHL5 | View Gene Set | 3.937e-06 | 33 | 0.00109 | 8 | Protein-protein-interaction for UCHL5 | www.ncbi.nlm.ni... |
Null ppi.PSMD13 | View Gene Set | 1.1e-05 | 20 | 0.002526 | 10 | Protein-protein-interaction for PSMD13 | www.ncbi.nlm.ni... |
Null ppi.72462 | View Gene Set | 1.514e-05 | 42 | 0.003161 | 11 | Protein-protein-interaction for 72462 | www.ncbi.nlm.ni... |
Null ppi.PAAF1 | View Gene Set | 1.779e-05 | 20 | 0.003405 | 12 | Protein-protein-interaction for PAAF1 | www.ncbi.nlm.ni... |
Null ppi.RNU12-2P | View Gene Set | 2.539e-05 | 18 | 0.003713 | 13 | Protein-protein-interaction for RNU12-2P | www.ncbi.nlm.ni... |
Null ppi.RNU11 | View Gene Set | 2.539e-05 | 18 | 0.003713 | 13 | Protein-protein-interaction for RNU11 | www.ncbi.nlm.ni... |
Null ppi.ING5 | View Gene Set | 2.586e-05 | 20 | 0.003713 | 13 | Protein-protein-interaction for ING5 | www.ncbi.nlm.ni... |
Null ppi.USP14 | View Gene Set | 2.566e-05 | 22 | 0.003713 | 13 | Protein-protein-interaction for USP14 | www.ncbi.nlm.ni... |
Null ppi.CHEK2 | View Gene Set | 3.372e-05 | 19 | 0.004303 | 17 | Protein-protein-interaction for CHEK2 | www.ncbi.nlm.ni... |
Null ppi.CDC16 | View Gene Set | 3.356e-05 | 10 | 0.004303 | 17 | Protein-protein-interaction for CDC16 | www.ncbi.nlm.ni... |
Null ppi.CDC7 | View Gene Set | 4.935e-05 | 7 | 0.005967 | 19 | Protein-protein-interaction for CDC7 | www.ncbi.nlm.ni... |
Null ppi.CBX5 | View Gene Set | 6.739e-05 | 38 | 0.007739 | 20 | Protein-protein-interaction for CBX5 | www.ncbi.nlm.ni... |
Null ppi.SF3B3 | View Gene Set | 8.011e-05 | 16 | 0.008762 | 21 | Protein-protein-interaction for SF3B3 | www.ncbi.nlm.ni... |
Null ppi.PSMD10 | View Gene Set | 9.778e-05 | 14 | 0.01012 | 22 | Protein-protein-interaction for PSMD10 | www.ncbi.nlm.ni... |
Null ppi.MCPH1 | View Gene Set | 0.0001013 | 17 | 0.01012 | 22 | Protein-protein-interaction for MCPH1 | www.ncbi.nlm.ni... |
Null ppi.NUP153 | View Gene Set | 0.0001089 | 11 | 0.01043 | 24 | Protein-protein-interaction for NUP153 | www.ncbi.nlm.ni... |
Null ppi.PSMD14 | View Gene Set | 0.0001497 | 16 | 0.01375 | 25 | Protein-protein-interaction for PSMD14 | www.ncbi.nlm.ni... |
Null ppi.MIS12 | View Gene Set | 0.0001869 | 9 | 0.01651 | 26 | Protein-protein-interaction for MIS12 | www.ncbi.nlm.ni... |
Null ppi.BCL7C | View Gene Set | 0.0002002 | 11 | 0.01685 | 27 | Protein-protein-interaction for BCL7C | www.ncbi.nlm.ni... |
Null ppi.PSMD6 | View Gene Set | 0.0002054 | 21 | 0.01685 | 27 | Protein-protein-interaction for PSMD6 | www.ncbi.nlm.ni... |
Null ppi.CTCF | View Gene Set | 0.0002289 | 6 | 0.01753 | 29 | Protein-protein-interaction for CTCF | www.ncbi.nlm.ni... |
Null ppi.RNPS1 | View Gene Set | 0.0002242 | 38 | 0.01753 | 29 | Protein-protein-interaction for RNPS1 | www.ncbi.nlm.ni... |
Null ppi.ZEB1 | View Gene Set | 0.0002413 | 6 | 0.01788 | 31 | Protein-protein-interaction for ZEB1 | www.ncbi.nlm.ni... |
Null ppi.HSPA8 | View Gene Set | 0.0003313 | 21 | 0.02378 | 32 | Protein-protein-interaction for HSPA8 | www.ncbi.nlm.ni... |
Null ppi.855836 | View Gene Set | 0.0003682 | 8 | 0.02487 | 33 | Protein-protein-interaction for 855836 | www.ncbi.nlm.ni... |
Null ppi.PRPF4 | View Gene Set | 0.0003612 | 11 | 0.02487 | 33 | Protein-protein-interaction for PRPF4 | www.ncbi.nlm.ni... |
Null ppi.ANAPC7 | View Gene Set | 0.0003791 | 12 | 0.02488 | 35 | Protein-protein-interaction for ANAPC7 | www.ncbi.nlm.ni... |
Null ppi.SSRP1 | View Gene Set | 0.0004056 | 15 | 0.02588 | 36 | Protein-protein-interaction for SSRP1 | www.ncbi.nlm.ni... |
Null ppi.DCUN1D1 | View Gene Set | 0.0004321 | 8 | 0.02683 | 37 | Protein-protein-interaction for DCUN1D1 | www.ncbi.nlm.ni... |
Null ppi.ORC2L | View Gene Set | 0.0005111 | 12 | 0.03089 | 38 | Protein-protein-interaction for ORC2L | www.ncbi.nlm.ni... |
Null ppi.CDT1 | View Gene Set | 0.0005519 | 37 | 0.03251 | 39 | Protein-protein-interaction for CDT1 | www.ncbi.nlm.ni... |
Null ppi.TCEAL1 | View Gene Set | 0.000627 | 10 | 0.03601 | 40 | Protein-protein-interaction for TCEAL1 | www.ncbi.nlm.ni... |
Null ppi.PRPF19 | View Gene Set | 0.000644 | 9 | 0.03608 | 41 | Protein-protein-interaction for PRPF19 | www.ncbi.nlm.ni... |
Null ppi.KLF1 | View Gene Set | 0.0006871 | 13 | 0.0367 | 42 | Protein-protein-interaction for KLF1 | www.ncbi.nlm.ni... |
Null ppi.RPA1 | View Gene Set | 0.0006778 | 23 | 0.0367 | 42 | Protein-protein-interaction for RPA1 | www.ncbi.nlm.ni... |
Null ppi.CDCA5 | View Gene Set | 0.0007292 | 6 | 0.03764 | 44 | Protein-protein-interaction for CDCA5 | www.ncbi.nlm.ni... |
Null ppi.DSN1 | View Gene Set | 0.0007375 | 8 | 0.03764 | 44 | Protein-protein-interaction for DSN1 | www.ncbi.nlm.ni... |
Null ppi.XPO5 | View Gene Set | 0.0007826 | 11 | 0.03901 | 46 | Protein-protein-interaction for XPO5 | www.ncbi.nlm.ni... |
Null ppi.TAF10 | View Gene Set | 0.0007982 | 27 | 0.03901 | 46 | Protein-protein-interaction for TAF10 | www.ncbi.nlm.ni... |
Null ppi.ANAPC1 | View Gene Set | 0.0008247 | 15 | 0.03947 | 48 | Protein-protein-interaction for ANAPC1 | www.ncbi.nlm.ni... |
Null ppi.CBX3 | View Gene Set | 0.0008535 | 23 | 0.03989 | 49 | Protein-protein-interaction for CBX3 | www.ncbi.nlm.ni... |
Null ppi.24831 | View Gene Set | 0.0008683 | 11 | 0.03989 | 49 | Protein-protein-interaction for 24831 | www.ncbi.nlm.ni... |
Null ppi.PSMD7 | View Gene Set | 0.0009243 | 12 | 0.04006 | 51 | Protein-protein-interaction for PSMD7 | www.ncbi.nlm.ni... |
Null ppi.TAF12 | View Gene Set | 0.000902 | 10 | 0.04006 | 51 | Protein-protein-interaction for TAF12 | www.ncbi.nlm.ni... |
Null ppi.SEH1L | View Gene Set | 0.0009182 | 6 | 0.04006 | 51 | Protein-protein-interaction for SEH1L | www.ncbi.nlm.ni... |
Null ppi.USP39 | View Gene Set | 0.001052 | 15 | 0.04396 | 54 | Protein-protein-interaction for USP39 | www.ncbi.nlm.ni... |
Null ppi.BRCC3 | View Gene Set | 0.001053 | 22 | 0.04396 | 54 | Protein-protein-interaction for BRCC3 | www.ncbi.nlm.ni... |
Null ppi.TCERG1 | View Gene Set | 0.001184 | 35 | 0.04599 | 56 | Protein-protein-interaction for TCERG1 | www.ncbi.nlm.ni... |
Null ppi.USP12 | View Gene Set | 0.001199 | 15 | 0.04599 | 56 | Protein-protein-interaction for USP12 | www.ncbi.nlm.ni... |
Null ppi.LSM1 | View Gene Set | 0.001201 | 13 | 0.04599 | 56 | Protein-protein-interaction for LSM1 | www.ncbi.nlm.ni... |
Null ppi.KPNA2 | View Gene Set | 0.001157 | 14 | 0.04599 | 56 | Protein-protein-interaction for KPNA2 | www.ncbi.nlm.ni... |
Null ppi.ATG4C | View Gene Set | 0.001154 | 10 | 0.04599 | 56 | Protein-protein-interaction for ATG4C | www.ncbi.nlm.ni... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null ppi.SFRS12 | View Gene Set | 2.6e-08 | 49 | 6.171e-05 | 1 | Protein-protein-interaction for SFRS12 | www.ncbi.nlm.ni... |
Null ppi.PRPF40A | View Gene Set | 1.262e-05 | 55 | 0.01498 | 2 | Protein-protein-interaction for PRPF40A | www.ncbi.nlm.ni... |
Null ppi.SF3B1 | View Gene Set | 4.426e-05 | 9 | 0.02884 | 3 | Protein-protein-interaction for SF3B1 | www.ncbi.nlm.ni... |
Null ppi.TAF11 | View Gene Set | 6.074e-05 | 12 | 0.02884 | 3 | Protein-protein-interaction for TAF11 | www.ncbi.nlm.ni... |
Null ppi.CDC16 | View Gene Set | 5.844e-05 | 10 | 0.02884 | 3 | Protein-protein-interaction for CDC16 | www.ncbi.nlm.ni... |
Null ppi.NAA38 | View Gene Set | 7.567e-05 | 20 | 0.02981 | 6 | Protein-protein-interaction for NAA38 | www.ncbi.nlm.ni... |
Null ppi.RAN | View Gene Set | 8.789e-05 | 14 | 0.02981 | 6 | Protein-protein-interaction for RAN | www.ncbi.nlm.ni... |
Null ppi.ECSIT | View Gene Set | 0.000131 | 7 | 0.03455 | 8 | Protein-protein-interaction for ECSIT | www.ncbi.nlm.ni... |
Null ppi.XPO5 | View Gene Set | 0.0001271 | 9 | 0.03455 | 8 | Protein-protein-interaction for XPO5 | www.ncbi.nlm.ni... |
Null ppi.NUP50 | View Gene Set | 0.0001863 | 6 | 0.03697 | 10 | Protein-protein-interaction for NUP50 | www.ncbi.nlm.ni... |
Null ppi.DBF4 | View Gene Set | 0.0001869 | 8 | 0.03697 | 10 | Protein-protein-interaction for DBF4 | www.ncbi.nlm.ni... |
Null ppi.COMMD1 | View Gene Set | 0.0001585 | 14 | 0.03697 | 10 | Protein-protein-interaction for COMMD1 | www.ncbi.nlm.ni... |
Null ppi.TAF10 | View Gene Set | 0.0002109 | 13 | 0.03851 | 13 | Protein-protein-interaction for TAF10 | www.ncbi.nlm.ni... |
Null ppi.PARP2 | View Gene Set | 0.0002803 | 7 | 0.03919 | 14 | Protein-protein-interaction for PARP2 | www.ncbi.nlm.ni... |
Null ppi.RAD51 | View Gene Set | 0.0002827 | 14 | 0.03919 | 14 | Protein-protein-interaction for RAD51 | www.ncbi.nlm.ni... |
Null ppi.RFX1 | View Gene Set | 0.0003136 | 11 | 0.03919 | 14 | Protein-protein-interaction for RFX1 | www.ncbi.nlm.ni... |
Null ppi.ZEB1 | View Gene Set | 0.0002976 | 6 | 0.03919 | 14 | Protein-protein-interaction for ZEB1 | www.ncbi.nlm.ni... |
Null ppi.MDC1 | View Gene Set | 0.0002927 | 11 | 0.03919 | 14 | Protein-protein-interaction for MDC1 | www.ncbi.nlm.ni... |
Null ppi.TGS1 | View Gene Set | 0.0002429 | 6 | 0.03919 | 14 | Protein-protein-interaction for TGS1 | www.ncbi.nlm.ni... |
Null ppi.ANAPC10 | View Gene Set | 0.0003633 | 8 | 0.03945 | 20 | Protein-protein-interaction for ANAPC10 | www.ncbi.nlm.ni... |
Null ppi.SCRIB | View Gene Set | 0.0003804 | 7 | 0.03945 | 20 | Protein-protein-interaction for SCRIB | www.ncbi.nlm.ni... |
Null ppi.SCAND1 | View Gene Set | 0.0003557 | 8 | 0.03945 | 20 | Protein-protein-interaction for SCAND1 | www.ncbi.nlm.ni... |
Null ppi.XRN1 | View Gene Set | 0.0003988 | 24 | 0.03945 | 20 | Protein-protein-interaction for XRN1 | www.ncbi.nlm.ni... |
Null ppi.MED9 | View Gene Set | 0.0003935 | 19 | 0.03945 | 20 | Protein-protein-interaction for MED9 | www.ncbi.nlm.ni... |
Null ppi.MIS12 | View Gene Set | 0.0004491 | 8 | 0.04264 | 25 | Protein-protein-interaction for MIS12 | www.ncbi.nlm.ni... |
Null ppi.TAF1 | View Gene Set | 0.000537 | 16 | 0.04904 | 26 | Protein-protein-interaction for TAF1 | www.ncbi.nlm.ni... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null ppi.155871 | View Gene Set | 2.416e-13 | 251 | 8.682e-10 | 1 | Protein-protein-interaction for 155871 | www.ncbi.nlm.ni... |
Null ppi.MEPCE | View Gene Set | 2.494e-12 | 147 | 4.482e-09 | 2 | Protein-protein-interaction for MEPCE | www.ncbi.nlm.ni... |
Null ppi.SRRM1 | View Gene Set | 8.134e-09 | 66 | 5.846e-06 | 3 | Protein-protein-interaction for SRRM1 | www.ncbi.nlm.ni... |
Null ppi.WBP4 | View Gene Set | 6.715e-09 | 35 | 5.846e-06 | 3 | Protein-protein-interaction for WBP4 | www.ncbi.nlm.ni... |
Null ppi.PRPF40A | View Gene Set | 8.128e-09 | 96 | 5.846e-06 | 3 | Protein-protein-interaction for PRPF40A | www.ncbi.nlm.ni... |
Null ppi.SFRS12 | View Gene Set | 1.498e-08 | 50 | 8.976e-06 | 6 | Protein-protein-interaction for SFRS12 | www.ncbi.nlm.ni... |
Null ppi.SRRM2 | View Gene Set | 9.842e-08 | 101 | 5.053e-05 | 7 | Protein-protein-interaction for SRRM2 | www.ncbi.nlm.ni... |
Null ppi.HIST1H4A | View Gene Set | 9.565e-07 | 31 | 0.0004297 | 8 | Protein-protein-interaction for HIST1H4A | www.ncbi.nlm.ni... |
Null ppi.UCHL5 | View Gene Set | 3.758e-06 | 34 | 0.001501 | 9 | Protein-protein-interaction for UCHL5 | www.ncbi.nlm.ni... |
Null ppi.KHDRBS2 | View Gene Set | 7.949e-06 | 48 | 0.002857 | 10 | Protein-protein-interaction for KHDRBS2 | www.ncbi.nlm.ni... |
Null ppi.CDC16 | View Gene Set | 9.105e-06 | 14 | 0.002975 | 11 | Protein-protein-interaction for CDC16 | www.ncbi.nlm.ni... |
Null ppi.PSMD13 | View Gene Set | 1.1e-05 | 20 | 0.003293 | 12 | Protein-protein-interaction for PSMD13 | www.ncbi.nlm.ni... |
Null ppi.TAF11 | View Gene Set | 1.248e-05 | 19 | 0.00345 | 13 | Protein-protein-interaction for TAF11 | www.ncbi.nlm.ni... |
Null ppi.72462 | View Gene Set | 1.514e-05 | 42 | 0.003886 | 14 | Protein-protein-interaction for 72462 | www.ncbi.nlm.ni... |
Null ppi.PAAF1 | View Gene Set | 1.779e-05 | 20 | 0.004262 | 15 | Protein-protein-interaction for PAAF1 | www.ncbi.nlm.ni... |
Null ppi.RNU12-2P | View Gene Set | 2.539e-05 | 18 | 0.005123 | 16 | Protein-protein-interaction for RNU12-2P | www.ncbi.nlm.ni... |
Null ppi.RNU11 | View Gene Set | 2.539e-05 | 18 | 0.005123 | 16 | Protein-protein-interaction for RNU11 | www.ncbi.nlm.ni... |
Null ppi.USP14 | View Gene Set | 2.566e-05 | 22 | 0.005123 | 16 | Protein-protein-interaction for USP14 | www.ncbi.nlm.ni... |
Null ppi.RAN | View Gene Set | 3.749e-05 | 15 | 0.007092 | 19 | Protein-protein-interaction for RAN | www.ncbi.nlm.ni... |
Null ppi.NUP153 | View Gene Set | 4.833e-05 | 16 | 0.008686 | 20 | Protein-protein-interaction for NUP153 | www.ncbi.nlm.ni... |
Null ppi.SSRP1 | View Gene Set | 5.321e-05 | 21 | 0.009106 | 21 | Protein-protein-interaction for SSRP1 | www.ncbi.nlm.ni... |
Null ppi.SF3B1 | View Gene Set | 8.75e-05 | 31 | 0.01258 | 22 | Protein-protein-interaction for SF3B1 | www.ncbi.nlm.ni... |
Null ppi.CBX5 | View Gene Set | 8.137e-05 | 46 | 0.01258 | 22 | Protein-protein-interaction for CBX5 | www.ncbi.nlm.ni... |
Null ppi.PSMD10 | View Gene Set | 7.739e-05 | 16 | 0.01258 | 22 | Protein-protein-interaction for PSMD10 | www.ncbi.nlm.ni... |
Null ppi.XPO5 | View Gene Set | 8.726e-05 | 14 | 0.01258 | 22 | Protein-protein-interaction for XPO5 | www.ncbi.nlm.ni... |
Null ppi.COMMD1 | View Gene Set | 0.0001023 | 15 | 0.01347 | 26 | Protein-protein-interaction for COMMD1 | www.ncbi.nlm.ni... |
Null ppi.PBRM1 | View Gene Set | 0.0001049 | 7 | 0.01347 | 26 | Protein-protein-interaction for PBRM1 | www.ncbi.nlm.ni... |
Null ppi.MCPH1 | View Gene Set | 0.0001013 | 17 | 0.01347 | 26 | Protein-protein-interaction for MCPH1 | www.ncbi.nlm.ni... |
Null ppi.SF3B3 | View Gene Set | 0.000112 | 19 | 0.01387 | 29 | Protein-protein-interaction for SF3B3 | www.ncbi.nlm.ni... |
Null ppi.PSMD14 | View Gene Set | 0.0001497 | 16 | 0.01793 | 30 | Protein-protein-interaction for PSMD14 | www.ncbi.nlm.ni... |
Null ppi.TPX2 | View Gene Set | 0.0001649 | 5 | 0.01874 | 31 | Protein-protein-interaction for TPX2 | www.ncbi.nlm.ni... |
Null ppi.NAA38 | View Gene Set | 0.0001669 | 28 | 0.01874 | 31 | Protein-protein-interaction for NAA38 | www.ncbi.nlm.ni... |
Null ppi.XRN1 | View Gene Set | 0.0001804 | 25 | 0.01919 | 33 | Protein-protein-interaction for XRN1 | www.ncbi.nlm.ni... |
Null ppi.MIS12 | View Gene Set | 0.0001869 | 9 | 0.01919 | 33 | Protein-protein-interaction for MIS12 | www.ncbi.nlm.ni... |
Null ppi.CDT1 | View Gene Set | 0.0001849 | 42 | 0.01919 | 33 | Protein-protein-interaction for CDT1 | www.ncbi.nlm.ni... |
Null ppi.BCL7C | View Gene Set | 0.0002002 | 11 | 0.01999 | 36 | Protein-protein-interaction for BCL7C | www.ncbi.nlm.ni... |
Null ppi.ANAPC10 | View Gene Set | 0.0002268 | 11 | 0.02145 | 37 | Protein-protein-interaction for ANAPC10 | www.ncbi.nlm.ni... |
Null ppi.ANAPC7 | View Gene Set | 0.0002253 | 15 | 0.02145 | 37 | Protein-protein-interaction for ANAPC7 | www.ncbi.nlm.ni... |
Null ppi.CHEK2 | View Gene Set | 0.0002464 | 33 | 0.02265 | 39 | Protein-protein-interaction for CHEK2 | www.ncbi.nlm.ni... |
Null ppi.MDC1 | View Gene Set | 0.0002521 | 24 | 0.02265 | 39 | Protein-protein-interaction for MDC1 | www.ncbi.nlm.ni... |
Null ppi.1460853 | View Gene Set | 0.0003758 | 6 | 0.03216 | 41 | Protein-protein-interaction for 1460853 | www.ncbi.nlm.ni... |
Null ppi.855836 | View Gene Set | 0.0003682 | 8 | 0.03216 | 41 | Protein-protein-interaction for 855836 | www.ncbi.nlm.ni... |
Null ppi.TAF12 | View Gene Set | 0.000393 | 16 | 0.03285 | 43 | Protein-protein-interaction for TAF12 | www.ncbi.nlm.ni... |
Null ppi.ECSIT | View Gene Set | 0.0004068 | 8 | 0.03323 | 44 | Protein-protein-interaction for ECSIT | www.ncbi.nlm.ni... |
Null ppi.TGS1 | View Gene Set | 0.0004269 | 8 | 0.0341 | 45 | Protein-protein-interaction for TGS1 | www.ncbi.nlm.ni... |
Null ppi.PSMD7 | View Gene Set | 0.0004502 | 13 | 0.03517 | 46 | Protein-protein-interaction for PSMD7 | www.ncbi.nlm.ni... |
Null ppi.ORC1L | View Gene Set | 0.0005443 | 11 | 0.04162 | 47 | Protein-protein-interaction for ORC1L | www.ncbi.nlm.ni... |
Null ppi.CTCF | View Gene Set | 0.0005913 | 11 | 0.04419 | 48 | Protein-protein-interaction for CTCF | www.ncbi.nlm.ni... |
Null ppi.SF3A3 | View Gene Set | 0.000646 | 8 | 0.04419 | 48 | Protein-protein-interaction for SF3A3 | www.ncbi.nlm.ni... |
Null ppi.CDCA5 | View Gene Set | 0.0007292 | 6 | 0.04419 | 48 | Protein-protein-interaction for CDCA5 | www.ncbi.nlm.ni... |
Null ppi.TAF8 | View Gene Set | 0.0007378 | 14 | 0.04419 | 48 | Protein-protein-interaction for TAF8 | www.ncbi.nlm.ni... |
Null ppi.PRPF19 | View Gene Set | 0.000644 | 9 | 0.04419 | 48 | Protein-protein-interaction for PRPF19 | www.ncbi.nlm.ni... |
Null ppi.LSM2 | View Gene Set | 0.0006848 | 26 | 0.04419 | 48 | Protein-protein-interaction for LSM2 | www.ncbi.nlm.ni... |
Null ppi.UPF1 | View Gene Set | 0.0006399 | 8 | 0.04419 | 48 | Protein-protein-interaction for UPF1 | www.ncbi.nlm.ni... |
Null ppi.SNRPA | View Gene Set | 0.000659 | 6 | 0.04419 | 48 | Protein-protein-interaction for SNRPA | www.ncbi.nlm.ni... |
Null ppi.ZEB1 | View Gene Set | 0.0006924 | 8 | 0.04419 | 48 | Protein-protein-interaction for ZEB1 | www.ncbi.nlm.ni... |
Null ppi.YY1 | View Gene Set | 0.0007065 | 39 | 0.04419 | 48 | Protein-protein-interaction for YY1 | www.ncbi.nlm.ni... |
Null ppi.USP7 | View Gene Set | 0.0006841 | 32 | 0.04419 | 48 | Protein-protein-interaction for USP7 | www.ncbi.nlm.ni... |
Null ppi.DSN1 | View Gene Set | 0.0007375 | 8 | 0.04419 | 48 | Protein-protein-interaction for DSN1 | www.ncbi.nlm.ni... |
Null ppi.PSMD6 | View Gene Set | 0.0006657 | 23 | 0.04419 | 48 | Protein-protein-interaction for PSMD6 | www.ncbi.nlm.ni... |
Null ppi.NUP50 | View Gene Set | 0.0008792 | 8 | 0.04755 | 61 | Protein-protein-interaction for NUP50 | www.ncbi.nlm.ni... |
Null ppi.SF3B2 | View Gene Set | 0.0009057 | 12 | 0.04755 | 61 | Protein-protein-interaction for SF3B2 | www.ncbi.nlm.ni... |
Null ppi.24831 | View Gene Set | 0.0008683 | 11 | 0.04755 | 61 | Protein-protein-interaction for 24831 | www.ncbi.nlm.ni... |
Null ppi.LSM1 | View Gene Set | 0.0008073 | 18 | 0.04755 | 61 | Protein-protein-interaction for LSM1 | www.ncbi.nlm.ni... |
Null ppi.CPSF1 | View Gene Set | 0.0009151 | 14 | 0.04755 | 61 | Protein-protein-interaction for CPSF1 | www.ncbi.nlm.ni... |
Null ppi.COPS7A | View Gene Set | 0.0008446 | 19 | 0.04755 | 61 | Protein-protein-interaction for COPS7A | www.ncbi.nlm.ni... |
Null ppi.NXF3 | View Gene Set | 0.0009262 | 6 | 0.04755 | 61 | Protein-protein-interaction for NXF3 | www.ncbi.nlm.ni... |
Null ppi.ANAPC1 | View Gene Set | 0.0008247 | 15 | 0.04755 | 61 | Protein-protein-interaction for ANAPC1 | www.ncbi.nlm.ni... |
Null ppi.CDK5RAP3 | View Gene Set | 0.0008599 | 14 | 0.04755 | 61 | Protein-protein-interaction for CDK5RAP3 | www.ncbi.nlm.ni... |
Null ppi.SEH1L | View Gene Set | 0.0009182 | 6 | 0.04755 | 61 | Protein-protein-interaction for SEH1L | www.ncbi.nlm.ni... |
Null ppi.ING5 | View Gene Set | 0.0009397 | 25 | 0.04757 | 71 | Protein-protein-interaction for ING5 | www.ncbi.nlm.ni... |
Null ppi.TXNRD2 | View Gene Set | 0.0009596 | 6 | 0.0479 | 72 | Protein-protein-interaction for TXNRD2 | www.ncbi.nlm.ni... |
Null ppi.EAPP | View Gene Set | 0.001063 | 6 | 0.0491 | 73 | Protein-protein-interaction for EAPP | www.ncbi.nlm.ni... |
Null ppi.PTMA | View Gene Set | 0.001034 | 21 | 0.0491 | 73 | Protein-protein-interaction for PTMA | www.ncbi.nlm.ni... |
Null ppi.TAF10 | View Gene Set | 0.001066 | 29 | 0.0491 | 73 | Protein-protein-interaction for TAF10 | www.ncbi.nlm.ni... |
Null ppi.BRCC3 | View Gene Set | 0.001053 | 22 | 0.0491 | 73 | Protein-protein-interaction for BRCC3 | www.ncbi.nlm.ni... |
Null ppi.PRPF4 | View Gene Set | 0.001008 | 12 | 0.0491 | 73 | Protein-protein-interaction for PRPF4 | www.ncbi.nlm.ni... |
Null ppi.SRSF2IP | View Gene Set | 0.001063 | 8 | 0.0491 | 73 | Protein-protein-interaction for SRSF2IP | www.ncbi.nlm.ni... |
Null ppi.ZNF8 | View Gene Set | 0.001092 | 6 | 0.04969 | 79 | Protein-protein-interaction for ZNF8 | www.ncbi.nlm.ni... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null TNF alpha/NF-kB | View Gene Set | 0.00105 | 170 | 0.0105 | 1 | CELL_MAP - TNF alpha/NF-kB gene set | www.pathwaycomm... |
Null AndrogenReceptor | View Gene Set | 0.00276 | 78 | 0.0138 | 2 | CELL_MAP - AndrogenReceptor gene set | www.pathwaycomm... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null Aurora B signaling | View Gene Set | 1.499e-05 | 41 | 0.002787 | 1 | NCI_NATURE - Aurora B signaling gene set | www.pathwaycomm... |
Null Validated targets of C-MYC transcriptional activation | View Gene Set | 0.0001888 | 80 | 0.0117 | 2 | NCI_NATURE - Validated targets of C-MYC transcriptional activation gene set | www.pathwaycomm... |
Null PLK1 signaling events | View Gene Set | 0.0001511 | 104 | 0.0117 | 2 | NCI_NATURE - PLK1 signaling events gene set | www.pathwaycomm... |
Null Signaling by Aurora kinases | View Gene Set | 0.0002879 | 98 | 0.01339 | 4 | NCI_NATURE - Signaling by Aurora kinases gene set | www.pathwaycomm... |
Null Polo-like kinase signaling events in the cell cycle | View Gene Set | 0.000464 | 109 | 0.01726 | 5 | NCI_NATURE - Polo-like kinase signaling events in the cell cycle gene set | www.pathwaycomm... |
Null BARD1 signaling events | View Gene Set | 0.0009672 | 29 | 0.02998 | 6 | NCI_NATURE - BARD1 signaling events gene set | www.pathwaycomm... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null Gene Expression | View Gene Set | 1.158e-18 | 381 | 1.294e-15 | 1 | REACTOME - Gene Expression gene set | www.pathwaycomm... |
Null DNA Replication | View Gene Set | 3.228e-16 | 200 | 1.803e-13 | 2 | REACTOME - DNA Replication gene set | www.pathwaycomm... |
Null Mitotic M-M/G1 phases | View Gene Set | 1.047e-15 | 180 | 3.897e-13 | 3 | REACTOME - Mitotic M-M/G1 phases gene set | www.pathwaycomm... |
Null Processing of Capped Intron-Containing Pre-mRNA | View Gene Set | 4.355e-15 | 138 | 1.216e-12 | 4 | REACTOME - Processing of Capped Intron-Containing Pre-mRNA gene set | www.pathwaycomm... |
Null mRNA Splicing - Major Pathway | View Gene Set | 1.826e-14 | 107 | 3.4e-12 | 5 | REACTOME - mRNA Splicing - Major Pathway gene set | www.pathwaycomm... |
Null mRNA Splicing | View Gene Set | 1.826e-14 | 107 | 3.4e-12 | 5 | REACTOME - mRNA Splicing gene set | www.pathwaycomm... |
Null Formation and Maturation of mRNA Transcript | View Gene Set | 4.243e-14 | 185 | 6.618e-12 | 7 | REACTOME - Formation and Maturation of mRNA Transcript gene set | www.pathwaycomm... |
Null Cell Cycle Mitotic | View Gene Set | 4.74e-14 | 312 | 6.618e-12 | 7 | REACTOME - Cell Cycle Mitotic gene set | www.pathwaycomm... Mitotic&format=... |
Null mRNA Processing | View Gene Set | 3.802e-13 | 158 | 4.719e-11 | 9 | REACTOME - mRNA Processing gene set | www.pathwaycomm... |
Null M Phase | View Gene Set | 1.111e-11 | 90 | 1.241e-09 | 10 | REACTOME - M Phase gene set | www.pathwaycomm... |
Null Mitotic Prometaphase | View Gene Set | 1.474e-10 | 86 | 1.497e-08 | 11 | REACTOME - Mitotic Prometaphase gene set | www.pathwaycomm... |
Null Metabolism of RNA | View Gene Set | 1.856e-10 | 174 | 1.728e-08 | 12 | REACTOME - Metabolism of RNA gene set | www.pathwaycomm... |
Null Cell Cycle Checkpoints | View Gene Set | 2.794e-09 | 124 | 2.401e-07 | 13 | REACTOME - Cell Cycle Checkpoints gene set | www.pathwaycomm... |
Null Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | View Gene Set | 1.819e-08 | 86 | 1.451e-06 | 14 | REACTOME - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins gene set | www.pathwaycomm... |
Null Regulation of mitotic cell cycle | View Gene Set | 2.533e-08 | 95 | 1.768e-06 | 15 | REACTOME - Regulation of mitotic cell cycle gene set | www.pathwaycomm... |
Null APC/C-mediated degradation of cell cycle proteins | View Gene Set | 2.533e-08 | 95 | 1.768e-06 | 15 | REACTOME - APC/C-mediated degradation of cell cycle proteins gene set | www.pathwaycomm... |
Null Post-Elongation Processing of the Transcript | View Gene Set | 3.236e-08 | 43 | 1.902e-06 | 17 | REACTOME - Post-Elongation Processing of the Transcript gene set | www.pathwaycomm... |
Null Cleavage of Growing Transcript in the Termination Region | View Gene Set | 3.236e-08 | 43 | 1.902e-06 | 17 | REACTOME - Cleavage of Growing Transcript in the Termination Region gene set | www.pathwaycomm... |
Null RNA Polymerase II Transcription Termination | View Gene Set | 3.236e-08 | 43 | 1.902e-06 | 17 | REACTOME - RNA Polymerase II Transcription Termination gene set | www.pathwaycomm... |
Null Regulation of APC/C activators between G1/S and early anaphase | View Gene Set | 7.832e-08 | 88 | 4.374e-06 | 20 | REACTOME - Regulation of APC/C activators between G1/S and early anaphase gene set | www.pathwaycomm... |
Null Post-Elongation Processing of Intron-Containing pre-mRNA | View Gene Set | 9.944e-08 | 34 | 5.049e-06 | 21 | REACTOME - Post-Elongation Processing of Intron-Containing pre-mRNA gene set | www.pathwaycomm... |
Null mRNA 3'-end processing | View Gene Set | 9.944e-08 | 34 | 5.049e-06 | 21 | REACTOME - mRNA 3'-end processing gene set | www.pathwaycomm... |
Null Transport of Mature mRNA derived from an Intron-Containing Transcript | View Gene Set | 3.353e-07 | 51 | 1.628e-05 | 23 | REACTOME - Transport of Mature mRNA derived from an Intron-Containing Transcript gene set | www.pathwaycomm... |
Null Metabolism of mRNA | View Gene Set | 4.473e-07 | 125 | 2.082e-05 | 24 | REACTOME - Metabolism of mRNA gene set | www.pathwaycomm... |
Null Transcription | View Gene Set | 5.729e-07 | 178 | 2.56e-05 | 25 | REACTOME - Transcription gene set | www.pathwaycomm... |
Null Phosphorylation of the APC/C | View Gene Set | 1.072e-06 | 26 | 4.604e-05 | 26 | REACTOME - Phosphorylation of the APC/C gene set | www.pathwaycomm... |
Null APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | View Gene Set | 1.718e-06 | 77 | 6.862e-05 | 27 | REACTOME - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 gene set | www.pathwaycomm... |
Null Deadenylation-dependent mRNA decay | View Gene Set | 1.72e-06 | 46 | 6.862e-05 | 27 | REACTOME - Deadenylation-dependent mRNA decay gene set | www.pathwaycomm... |
Null DNA Replication Pre-Initiation | View Gene Set | 2.4e-06 | 90 | 8.936e-05 | 29 | REACTOME - DNA Replication Pre-Initiation gene set | www.pathwaycomm... |
Null M/G1 Transition | View Gene Set | 2.4e-06 | 90 | 8.936e-05 | 29 | REACTOME - M/G1 Transition gene set | www.pathwaycomm... |
Null Transport of Mature Transcript to Cytoplasm | View Gene Set | 2.91e-06 | 55 | 0.0001016 | 31 | REACTOME - Transport of Mature Transcript to Cytoplasm gene set | www.pathwaycomm... |
Null Cdc20:Phospho-APC/C mediated degradation of Cyclin A | View Gene Set | 2.826e-06 | 75 | 0.0001016 | 31 | REACTOME - Cdc20:Phospho-APC/C mediated degradation of Cyclin A gene set | www.pathwaycomm... |
Null APC/C:Cdc20 mediated degradation of mitotic proteins | View Gene Set | 3.124e-06 | 77 | 0.0001057 | 33 | REACTOME - APC/C:Cdc20 mediated degradation of mitotic proteins gene set | www.pathwaycomm... |
Null G1/S Transition | View Gene Set | 3.247e-06 | 104 | 0.0001067 | 34 | REACTOME - G1/S Transition gene set | www.pathwaycomm... |
Null Deadenylation of mRNA | View Gene Set | 5.586e-06 | 22 | 0.0001783 | 35 | REACTOME - Deadenylation of mRNA gene set | www.pathwaycomm... |
Null Autodegradation of Cdh1 by Cdh1:APC/C | View Gene Set | 6.407e-06 | 67 | 0.0001988 | 36 | REACTOME - Autodegradation of Cdh1 by Cdh1:APC/C gene set | www.pathwaycomm... |
Null Mitotic G1-G1/S phases | View Gene Set | 1.063e-05 | 113 | 0.0003209 | 37 | REACTOME - Mitotic G1-G1/S phases gene set | www.pathwaycomm... |
Null Phosphorylation of Emi1 | View Gene Set | 1.143e-05 | 12 | 0.000336 | 38 | REACTOME - Phosphorylation of Emi1 gene set | www.pathwaycomm... |
Null Assembly of the pre-replicative complex | View Gene Set | 1.552e-05 | 75 | 0.0004334 | 39 | REACTOME - Assembly of the pre-replicative complex gene set | www.pathwaycomm... |
Null S Phase | View Gene Set | 1.544e-05 | 113 | 0.0004334 | 39 | REACTOME - S Phase gene set | www.pathwaycomm... |
Null HIV Infection | View Gene Set | 1.613e-05 | 194 | 0.0004396 | 41 | REACTOME - HIV Infection gene set | www.pathwaycomm... |
Null Synthesis of DNA | View Gene Set | 1.677e-05 | 102 | 0.0004461 | 42 | REACTOME - Synthesis of DNA gene set | www.pathwaycomm... |
Null Host Interactions of HIV factors | View Gene Set | 1.791e-05 | 132 | 0.0004653 | 43 | REACTOME - Host Interactions of HIV factors gene set | www.pathwaycomm... |
Null snRNP Assembly | View Gene Set | 1.921e-05 | 50 | 0.0004767 | 44 | REACTOME - snRNP Assembly gene set | www.pathwaycomm... |
Null Metabolism of non-coding RNA | View Gene Set | 1.921e-05 | 50 | 0.0004767 | 44 | REACTOME - Metabolism of non-coding RNA gene set | www.pathwaycomm... |
Null RNA Polymerase II Transcription | View Gene Set | 2.024e-05 | 101 | 0.0004915 | 46 | REACTOME - RNA Polymerase II Transcription gene set | www.pathwaycomm... |
Null p53-Independent G1/S DNA damage checkpoint | View Gene Set | 2.574e-05 | 62 | 0.000599 | 47 | REACTOME - p53-Independent G1/S DNA damage checkpoint gene set | www.pathwaycomm... |
Null p53-Independent DNA Damage Response | View Gene Set | 2.574e-05 | 62 | 0.000599 | 47 | REACTOME - p53-Independent DNA Damage Response gene set | www.pathwaycomm... |
Null G1/S DNA Damage Checkpoints | View Gene Set | 3.018e-05 | 68 | 0.0006742 | 49 | REACTOME - G1/S DNA Damage Checkpoints gene set | www.pathwaycomm... |
Null Regulation of DNA replication | View Gene Set | 2.995e-05 | 81 | 0.0006742 | 49 | REACTOME - Regulation of DNA replication gene set | www.pathwaycomm... |
Null APC/C:Cdc20 mediated degradation of Securin | View Gene Set | 4.67e-05 | 72 | 0.001023 | 51 | REACTOME - APC/C:Cdc20 mediated degradation of Securin gene set | www.pathwaycomm... |
Null Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | View Gene Set | 5.317e-05 | 61 | 0.001138 | 52 | REACTOME - Ubiquitin Mediated Degradation of Phosphorylated Cdc25A gene set | www.pathwaycomm... |
Null Mitotic Telophase /Cytokinesis | View Gene Set | 5.398e-05 | 10 | 0.001138 | 52 | REACTOME - Mitotic Telophase /Cytokinesis gene set | www.pathwaycomm... |
Null Removal of licensing factors from origins | View Gene Set | 7.699e-05 | 78 | 0.001593 | 54 | REACTOME - Removal of licensing factors from origins gene set | www.pathwaycomm... |
Null Vif-mediated degradation of APOBEC3G | View Gene Set | 9.82e-05 | 61 | 0.00199 | 55 | REACTOME - Vif-mediated degradation of APOBEC3G gene set | www.pathwaycomm... |
Null G2/M Checkpoints | View Gene Set | 9.979e-05 | 43 | 0.00199 | 55 | REACTOME - G2/M Checkpoints gene set | www.pathwaycomm... |
Null Ubiquitin-dependent degradation of Cyclin D1 | View Gene Set | 0.0001104 | 59 | 0.002126 | 57 | REACTOME - Ubiquitin-dependent degradation of Cyclin D1 gene set | www.pathwaycomm... |
Null Ubiquitin-dependent degradation of Cyclin D | View Gene Set | 0.0001104 | 59 | 0.002126 | 57 | REACTOME - Ubiquitin-dependent degradation of Cyclin D gene set | www.pathwaycomm... |
Null Polo-like kinase mediated events | View Gene Set | 0.0001163 | 10 | 0.002203 | 59 | REACTOME - Polo-like kinase mediated events gene set | www.pathwaycomm... |
Null Interactions of Rev with host cellular proteins | View Gene Set | 0.0001302 | 33 | 0.002384 | 60 | REACTOME - Interactions of Rev with host cellular proteins gene set | www.pathwaycomm... |
Null Stabilization of p53 | View Gene Set | 0.0001295 | 61 | 0.002384 | 60 | REACTOME - Stabilization of p53 gene set | www.pathwaycomm... |
Null Influenza Infection | View Gene Set | 0.0001506 | 143 | 0.002714 | 62 | REACTOME - Influenza Infection gene set | www.pathwaycomm... |
Null SCF(Skp2)-mediated degradation of p27/p21 | View Gene Set | 0.0001691 | 52 | 0.002998 | 63 | REACTOME - SCF(Skp2)-mediated degradation of p27/p21 gene set | www.pathwaycomm... |
Null Autodegradation of the E3 ubiquitin ligase COP1 | View Gene Set | 0.0001934 | 60 | 0.003376 | 64 | REACTOME - Autodegradation of the E3 ubiquitin ligase COP1 gene set | www.pathwaycomm... |
Null Switching of origins to a post-replicative state | View Gene Set | 0.0002004 | 76 | 0.003392 | 65 | REACTOME - Switching of origins to a post-replicative state gene set | www.pathwaycomm... |
Null Orc1 removal from chromatin | View Gene Set | 0.0002004 | 76 | 0.003392 | 65 | REACTOME - Orc1 removal from chromatin gene set | www.pathwaycomm... |
Null Mitotic Metaphase/Anaphase Transition | View Gene Set | 0.0002199 | 8 | 0.003667 | 67 | REACTOME - Mitotic Metaphase/Anaphase Transition gene set | www.pathwaycomm... |
Null Pyrimidine biosynthesis | View Gene Set | 0.0002975 | 6 | 0.004886 | 68 | REACTOME - Pyrimidine biosynthesis gene set | www.pathwaycomm... |
Null G2/M DNA damage checkpoint | View Gene Set | 0.0003093 | 29 | 0.004981 | 69 | REACTOME - G2/M DNA damage checkpoint gene set | www.pathwaycomm... |
Null p53-Dependent G1/S DNA damage checkpoint | View Gene Set | 0.0003166 | 64 | 0.004981 | 69 | REACTOME - p53-Dependent G1/S DNA damage checkpoint gene set | www.pathwaycomm... |
Null p53-Dependent G1 DNA Damage Response | View Gene Set | 0.0003166 | 64 | 0.004981 | 69 | REACTOME - p53-Dependent G1 DNA Damage Response gene set | www.pathwaycomm... |
Null Regulation of activated PAK-2p34 by proteasome mediated degradation | View Gene Set | 0.0003466 | 57 | 0.005151 | 72 | REACTOME - Regulation of activated PAK-2p34 by proteasome mediated degradation gene set | www.pathwaycomm... |
Null Rev-mediated nuclear export of HIV-1 RNA | View Gene Set | 0.000334 | 32 | 0.005151 | 72 | REACTOME - Rev-mediated nuclear export of HIV-1 RNA gene set | www.pathwaycomm... |
Null Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | View Gene Set | 0.0003451 | 18 | 0.005151 | 72 | REACTOME - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components gene set | www.pathwaycomm... |
Null Inactivation of APC/C via direct inhibition of the APC/C complex | View Gene Set | 0.0003451 | 18 | 0.005151 | 72 | REACTOME - Inactivation of APC/C via direct inhibition of the APC/C complex gene set | www.pathwaycomm... |
Null DNA strand elongation | View Gene Set | 0.0003505 | 31 | 0.005151 | 72 | REACTOME - DNA strand elongation gene set | www.pathwaycomm... |
Null Degradation of beta-catenin by the destruction complex | View Gene Set | 0.0004646 | 56 | 0.006645 | 77 | REACTOME - Degradation of beta-catenin by the destruction complex gene set | www.pathwaycomm... |
Null Signaling by Wnt | View Gene Set | 0.0004646 | 56 | 0.006645 | 77 | REACTOME - Signaling by Wnt gene set | www.pathwaycomm... |
Null Vpu mediated degradation of CD4 | View Gene Set | 0.0004699 | 57 | 0.006645 | 77 | REACTOME - Vpu mediated degradation of CD4 gene set | www.pathwaycomm... |
Null Destabilization of mRNA by AUF1 (hnRNP D0) | View Gene Set | 0.0004774 | 63 | 0.006665 | 80 | REACTOME - Destabilization of mRNA by AUF1 (hnRNP D0) gene set | www.pathwaycomm... |
Null Influenza Life Cycle | View Gene Set | 0.0004971 | 138 | 0.006856 | 81 | REACTOME - Influenza Life Cycle gene set | www.pathwaycomm... |
Null Double-Strand Break Repair | View Gene Set | 0.0005185 | 27 | 0.007063 | 82 | REACTOME - Double-Strand Break Repair gene set | www.pathwaycomm... |
Null tRNA Aminoacylation | View Gene Set | 0.0005269 | 42 | 0.007091 | 83 | REACTOME - tRNA Aminoacylation gene set | www.pathwaycomm... |
Null mRNA Splicing - Minor Pathway | View Gene Set | 0.0005674 | 42 | 0.007512 | 84 | REACTOME - mRNA Splicing - Minor Pathway gene set | www.pathwaycomm... |
Null Translation | View Gene Set | 0.0005716 | 120 | 0.007512 | 84 | REACTOME - Translation gene set | www.pathwaycomm... |
Null GTP hydrolysis and joining of the 60S ribosomal subunit | View Gene Set | 0.000597 | 106 | 0.007754 | 86 | REACTOME - GTP hydrolysis and joining of the 60S ribosomal subunit gene set | www.pathwaycomm... |
Null Cyclin A:Cdk2-associated events at S phase entry | View Gene Set | 0.000613 | 62 | 0.00787 | 87 | REACTOME - Cyclin A:Cdk2-associated events at S phase entry gene set | www.pathwaycomm... |
Null SCF-beta-TrCP mediated degradation of Emi1 | View Gene Set | 0.0006295 | 60 | 0.00799 | 88 | REACTOME - SCF-beta-TrCP mediated degradation of Emi1 gene set | www.pathwaycomm... |
Null Cap-dependent Translation Initiation | View Gene Set | 0.0006772 | 113 | 0.008405 | 89 | REACTOME - Cap-dependent Translation Initiation gene set | www.pathwaycomm... |
Null Eukaryotic Translation Initiation | View Gene Set | 0.0006772 | 113 | 0.008405 | 89 | REACTOME - Eukaryotic Translation Initiation gene set | www.pathwaycomm... |
Null Nuclear import of Rev protein | View Gene Set | 0.0007059 | 30 | 0.008664 | 91 | REACTOME - Nuclear import of Rev protein gene set | www.pathwaycomm... |
Null 3' -UTR-mediated translational regulation | View Gene Set | 0.0008563 | 105 | 0.01029 | 92 | REACTOME - 3' -UTR-mediated translational regulation gene set | www.pathwaycomm... |
Null L13a-mediated translational silencing of Ceruloplasmin expression | View Gene Set | 0.0008563 | 105 | 0.01029 | 92 | REACTOME - L13a-mediated translational silencing of Ceruloplasmin expression gene set | www.pathwaycomm... |
Null Mitotic G2-G2/M phases | View Gene Set | 0.0008698 | 98 | 0.01034 | 94 | REACTOME - Mitotic G2-G2/M phases gene set | www.pathwaycomm... |
Null HIV Life Cycle | View Gene Set | 0.0009872 | 103 | 0.01161 | 95 | REACTOME - HIV Life Cycle gene set | www.pathwaycomm... |
Null Transport of Ribonucleoproteins into the Host Nucleus | View Gene Set | 0.001139 | 29 | 0.01325 | 96 | REACTOME - Transport of Ribonucleoproteins into the Host Nucleus gene set | www.pathwaycomm... |
Null TRAF3-dependent IRF activation pathway | View Gene Set | 0.001166 | 10 | 0.01338 | 97 | REACTOME - TRAF3-dependent IRF activation pathway gene set | www.pathwaycomm... |
Null NEP/NS2 Interacts with the Cellular Export Machinery | View Gene Set | 0.001174 | 29 | 0.01338 | 97 | REACTOME - NEP/NS2 Interacts with the Cellular Export Machinery gene set | www.pathwaycomm... |
Null Metabolism of nucleotides | View Gene Set | 0.001255 | 66 | 0.01416 | 99 | REACTOME - Metabolism of nucleotides gene set | www.pathwaycomm... |
Null CDT1 association with the CDC6:ORC:origin complex | View Gene Set | 0.0013 | 66 | 0.01452 | 100 | REACTOME - CDT1 association with the CDC6:ORC:origin complex gene set | www.pathwaycomm... |
Null Cyclin E associated events during G1/S transition | View Gene Set | 0.001399 | 64 | 0.01547 | 101 | REACTOME - Cyclin E associated events during G1/S transition gene set | www.pathwaycomm... |
Null Pyrimidine metabolism | View Gene Set | 0.00146 | 23 | 0.01599 | 102 | REACTOME - Pyrimidine metabolism gene set | www.pathwaycomm... |
Null DNA Repair | View Gene Set | 0.001489 | 108 | 0.01599 | 103 | REACTOME - DNA Repair gene set | www.pathwaycomm... |
Null Recruitment of NuMA to mitotic centrosomes | View Gene Set | 0.001486 | 14 | 0.01599 | 103 | REACTOME - Recruitment of NuMA to mitotic centrosomes gene set | www.pathwaycomm... |
Null Mitotic Spindle Checkpoint | View Gene Set | 0.001566 | 19 | 0.0165 | 105 | REACTOME - Mitotic Spindle Checkpoint gene set | www.pathwaycomm... |
Null Formation of a pool of free 40S subunits | View Gene Set | 0.001558 | 95 | 0.0165 | 105 | REACTOME - Formation of a pool of free 40S subunits gene set | www.pathwaycomm... |
Null Homologous Recombination Repair | View Gene Set | 0.001786 | 22 | 0.01831 | 107 | REACTOME - Homologous Recombination Repair gene set | www.pathwaycomm... |
Null Homologous recombination repair of replication-independent double-strand breaks | View Gene Set | 0.001786 | 22 | 0.01831 | 107 | REACTOME - Homologous recombination repair of replication-independent double-strand breaks gene set | www.pathwaycomm... |
Null CDK-mediated phosphorylation and removal of Cdc6 | View Gene Set | 0.001758 | 58 | 0.01831 | 107 | REACTOME - CDK-mediated phosphorylation and removal of Cdc6 gene set | www.pathwaycomm... |
Null G2/M Transition | View Gene Set | 0.001848 | 96 | 0.01876 | 110 | REACTOME - G2/M Transition gene set | www.pathwaycomm... |
Null Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | View Gene Set | 0.002061 | 16 | 0.02074 | 111 | REACTOME - Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase gene set | www.pathwaycomm... |
Null Chromosome Maintenance | View Gene Set | 0.002286 | 69 | 0.0228 | 112 | REACTOME - Chromosome Maintenance gene set | www.pathwaycomm... |
Null Activation of ATR in response to replication stress | View Gene Set | 0.002354 | 37 | 0.02327 | 113 | REACTOME - Activation of ATR in response to replication stress gene set | www.pathwaycomm... |
Null Late Phase of HIV Life Cycle | View Gene Set | 0.002722 | 92 | 0.02667 | 114 | REACTOME - Late Phase of HIV Life Cycle gene set | www.pathwaycomm... |
Null Regulation of Apoptosis | View Gene Set | 0.003045 | 66 | 0.02933 | 115 | REACTOME - Regulation of Apoptosis gene set | www.pathwaycomm... |
Null Post-Elongation Processing of Intronless pre-mRNA | View Gene Set | 0.003072 | 23 | 0.02933 | 115 | REACTOME - Post-Elongation Processing of Intronless pre-mRNA gene set | www.pathwaycomm... |
Null Processing of Capped Intronless Pre-mRNA | View Gene Set | 0.003072 | 23 | 0.02933 | 115 | REACTOME - Processing of Capped Intronless Pre-mRNA gene set | www.pathwaycomm... |
Null Regulation of mRNA Stability by Proteins that Bind AU-rich Elements | View Gene Set | 0.003269 | 95 | 0.03095 | 118 | REACTOME - Regulation of mRNA Stability by Proteins that Bind AU-rich Elements gene set | www.pathwaycomm... |
Null Regulation of ornithine decarboxylase (ODC) | View Gene Set | 0.003369 | 62 | 0.03163 | 119 | REACTOME - Regulation of ornithine decarboxylase (ODC) gene set | www.pathwaycomm... |
Null Mitochondrial tRNA aminoacylation | View Gene Set | 0.003462 | 21 | 0.03223 | 120 | REACTOME - Mitochondrial tRNA aminoacylation gene set | www.pathwaycomm... |
Null Eukaryotic Translation Termination | View Gene Set | 0.003513 | 85 | 0.03243 | 121 | REACTOME - Eukaryotic Translation Termination gene set | www.pathwaycomm... |
Null Export of Viral Ribonucleoproteins from Nucleus | View Gene Set | 0.003695 | 31 | 0.03383 | 122 | REACTOME - Export of Viral Ribonucleoproteins from Nucleus gene set | www.pathwaycomm... |
Null Activation of the pre-replicative complex | View Gene Set | 0.003989 | 30 | 0.03622 | 123 | REACTOME - Activation of the pre-replicative complex gene set | www.pathwaycomm... |
Null Telomere C-strand (Lagging Strand) Synthesis | View Gene Set | 0.004213 | 22 | 0.03795 | 124 | REACTOME - Telomere C-strand (Lagging Strand) Synthesis gene set | www.pathwaycomm... |
Null Chaperonin-mediated protein folding | View Gene Set | 0.004624 | 16 | 0.04107 | 125 | REACTOME - Chaperonin-mediated protein folding gene set | www.pathwaycomm... |
Null Insulin Synthesis and Processing | View Gene Set | 0.004632 | 132 | 0.04107 | 125 | REACTOME - Insulin Synthesis and Processing gene set | www.pathwaycomm... |
Null Viral mRNA Translation | View Gene Set | 0.004737 | 85 | 0.04166 | 127 | REACTOME - Viral mRNA Translation gene set | www.pathwaycomm... |
Null Prefoldin mediated transfer of substrate to CCT/TriC | View Gene Set | 0.005411 | 14 | 0.04722 | 128 | REACTOME - Prefoldin mediated transfer of substrate to CCT/TriC gene set | www.pathwaycomm... |
Null NS1 Mediated Effects on Host Pathways | View Gene Set | 0.005522 | 3 | 0.04781 | 129 | REACTOME - NS1 Mediated Effects on Host Pathways gene set | www.pathwaycomm... |
Null Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | View Gene Set | 0.00558 | 6 | 0.04794 | 130 | REACTOME - Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex gene set | www.pathwaycomm... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null hsa-miR-548b-5p | View Gene Set | 6.384e-06 | 818 | 0.004539 | 1 | microRNA targets for hsa-miR-548b-5p from mirbase.targets | www.mirbase.org... |
Null hsa-miR-196a* | View Gene Set | 2.55e-05 | 526 | 0.009067 | 2 | microRNA targets for hsa-miR-196a* from mirbase.targets | www.mirbase.org... |
Null hsa-miR-495 | View Gene Set | 7.397e-05 | 796 | 0.01753 | 3 | microRNA targets for hsa-miR-495 from mirbase.targets | www.mirbase.org... |
Null hsa-miR-23a | View Gene Set | 0.0001656 | 807 | 0.02943 | 4 | microRNA targets for hsa-miR-23a from mirbase.targets | www.mirbase.org... |
Null hsa-miR-190 | View Gene Set | 0.0002746 | 668 | 0.03027 | 5 | microRNA targets for hsa-miR-190 from mirbase.targets | www.mirbase.org... |
Null hsa-miR-28-3p | View Gene Set | 0.0003264 | 712 | 0.03027 | 5 | microRNA targets for hsa-miR-28-3p from mirbase.targets | www.mirbase.org... |
Null hsa-miR-548d-5p | View Gene Set | 0.0003406 | 795 | 0.03027 | 5 | microRNA targets for hsa-miR-548d-5p from mirbase.targets | www.mirbase.org... |
Null hsa-miR-590-3p | View Gene Set | 0.0003148 | 742 | 0.03027 | 5 | microRNA targets for hsa-miR-590-3p from mirbase.targets | www.mirbase.org... |
Null hsa-miR-101* | View Gene Set | 0.000422 | 605 | 0.03334 | 9 | microRNA targets for hsa-miR-101* from mirbase.targets | www.mirbase.org... |
Null hsa-miR-548c-5p | View Gene Set | 0.0005319 | 801 | 0.03782 | 10 | microRNA targets for hsa-miR-548c-5p from mirbase.targets | www.mirbase.org... |
Null hsa-miR-494 | View Gene Set | 0.0006741 | 637 | 0.04357 | 11 | microRNA targets for hsa-miR-494 from mirbase.targets | www.mirbase.org... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null V_YY1_02 | View Gene Set | 7.552e-05 | 163 | 0.01609 | 1 | List of genes containing a conserved (FDR < 0.1%) V$YY1_02 TFBS located within 3 kb around the TSS for the YY1 transcription factor | www.gene-regula... |