Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
KEGG 03010 | View Gene Set | 1.053e-25 | 88 | 2.252e-23 | 1 | Ribosome | www.genome.jp/d... |
KEGG 01100 | View Gene Set | 3.734e-25 | 1120 | 3.995e-23 | 2 | Metabolic pathways | www.genome.jp/d... |
KEGG 04141 | View Gene Set | 1.129e-21 | 167 | 8.05e-20 | 3 | Protein processing in endoplasmic reticulum | www.genome.jp/d... |
KEGG 03040 | View Gene Set | 4.301e-20 | 128 | 2.301e-18 | 4 | Spliceosome | www.genome.jp/d... |
KEGG 04110 | View Gene Set | 1.503e-15 | 128 | 6.431e-14 | 5 | Cell cycle | www.genome.jp/d... |
KEGG 00190 | View Gene Set | 3.557e-12 | 134 | 1.269e-10 | 6 | Oxidative phosphorylation | www.genome.jp/d... |
KEGG 00240 | View Gene Set | 1.265e-10 | 99 | 3.868e-09 | 7 | Pyrimidine metabolism | www.genome.jp/d... |
KEGG 04120 | View Gene Set | 1.785e-10 | 139 | 4.776e-09 | 8 | Ubiquitin mediated proteolysis | www.genome.jp/d... |
KEGG 05016 | View Gene Set | 2.351e-10 | 184 | 5.591e-09 | 9 | Huntington's disease | www.genome.jp/d... |
KEGG 03018 | View Gene Set | 3.206e-10 | 59 | 6.861e-09 | 10 | RNA degradation | www.genome.jp/d... |
KEGG 05012 | View Gene Set | 3.986e-09 | 132 | 7.755e-08 | 11 | Parkinson's disease | www.genome.jp/d... |
KEGG 05010 | View Gene Set | 5.814e-09 | 168 | 1.037e-07 | 12 | Alzheimer's disease | www.genome.jp/d... |
KEGG 03050 | View Gene Set | 2.783e-08 | 48 | 4.581e-07 | 13 | Proteasome | www.genome.jp/d... |
KEGG 04114 | View Gene Set | 7.883e-08 | 114 | 1.205e-06 | 14 | Oocyte meiosis | www.genome.jp/d... |
KEGG 00970 | View Gene Set | 9.561e-08 | 41 | 1.364e-06 | 15 | Aminoacyl-tRNA biosynthesis | www.genome.jp/d... |
KEGG 03060 | View Gene Set | 2.231e-07 | 24 | 2.984e-06 | 16 | Protein export | www.genome.jp/d... |
KEGG 03030 | View Gene Set | 3.726e-07 | 36 | 4.69e-06 | 17 | DNA replication | www.genome.jp/d... |
KEGG 03420 | View Gene Set | 1.498e-06 | 44 | 1.781e-05 | 18 | Nucleotide excision repair | www.genome.jp/d... |
KEGG 00020 | View Gene Set | 1.662e-06 | 31 | 1.872e-05 | 19 | Citrate cycle (TCA cycle) | www.genome.jp/d... |
KEGG 05131 | View Gene Set | 1.779e-06 | 64 | 1.904e-05 | 20 | Shigellosis | www.genome.jp/d... |
KEGG 05215 | View Gene Set | 2.258e-06 | 89 | 2.301e-05 | 21 | Prostate cancer | www.genome.jp/d... |
KEGG 05220 | View Gene Set | 2.457e-06 | 73 | 2.39e-05 | 22 | Chronic myeloid leukemia | www.genome.jp/d... |
KEGG 03410 | View Gene Set | 1.029e-05 | 34 | 9.177e-05 | 23 | Base excision repair | www.genome.jp/d... |
KEGG 04150 | View Gene Set | 1.01e-05 | 52 | 9.177e-05 | 23 | mTOR signaling pathway | www.genome.jp/d... |
KEGG 00510 | View Gene Set | 1.814e-05 | 48 | 0.0001553 | 25 | N-Glycan biosynthesis | www.genome.jp/d... |
KEGG 00270 | View Gene Set | 2.633e-05 | 34 | 0.0002167 | 26 | Cysteine and methionine metabolism | www.genome.jp/d... |
KEGG 05212 | View Gene Set | 2.764e-05 | 70 | 0.0002191 | 27 | Pancreatic cancer | www.genome.jp/d... |
KEGG 05222 | View Gene Set | 6.741e-05 | 84 | 0.0005152 | 28 | Small cell lung cancer | www.genome.jp/d... |
KEGG 00230 | View Gene Set | 9.791e-05 | 161 | 0.0006682 | 29 | Purine metabolism | www.genome.jp/d... |
KEGG 04146 | View Gene Set | 9.992e-05 | 78 | 0.0006682 | 29 | Peroxisome | www.genome.jp/d... |
KEGG 04210 | View Gene Set | 9.881e-05 | 88 | 0.0006682 | 29 | Apoptosis | www.genome.jp/d... |
KEGG 05223 | View Gene Set | 9.437e-05 | 54 | 0.0006682 | 29 | Non-small cell lung cancer | www.genome.jp/d... |
KEGG 04914 | View Gene Set | 0.0001131 | 87 | 0.0007332 | 33 | Progesterone-mediated oocyte maturation | www.genome.jp/d... |
KEGG 05219 | View Gene Set | 0.0001514 | 42 | 0.000953 | 34 | Bladder cancer | www.genome.jp/d... |
KEGG 03430 | View Gene Set | 0.0004161 | 23 | 0.002544 | 35 | Mismatch repair | www.genome.jp/d... |
KEGG 00310 | View Gene Set | 0.0004374 | 46 | 0.0026 | 36 | Lysine degradation | www.genome.jp/d... |
KEGG 04142 | View Gene Set | 0.0004517 | 121 | 0.002612 | 37 | Lysosome | www.genome.jp/d... |
KEGG 05213 | View Gene Set | 0.0004858 | 52 | 0.002736 | 38 | Endometrial cancer | www.genome.jp/d... |
KEGG 04962 | View Gene Set | 0.0006568 | 44 | 0.003604 | 39 | Vasopressin-regulated water reabsorption | www.genome.jp/d... |
KEGG 05221 | View Gene Set | 0.0007613 | 60 | 0.004073 | 40 | Acute myeloid leukemia | www.genome.jp/d... |
KEGG 05100 | View Gene Set | 0.001324 | 73 | 0.006912 | 41 | Bacterial invasion of epithelial cells | www.genome.jp/d... |
KEGG 00290 | View Gene Set | 0.00167 | 11 | 0.008511 | 42 | Valine leucine and isoleucine biosynthesis | www.genome.jp/d... |
KEGG 05214 | View Gene Set | 0.001772 | 65 | 0.008702 | 43 | Glioma | www.genome.jp/d... |
KEGG 05216 | View Gene Set | 0.001789 | 29 | 0.008702 | 43 | Thyroid cancer | www.genome.jp/d... |
KEGG 00670 | View Gene Set | 0.001855 | 17 | 0.008823 | 45 | One carbon pool by folate | www.genome.jp/d... |
KEGG 00330 | View Gene Set | 0.001947 | 54 | 0.009056 | 46 | Arginine and proline metabolism | www.genome.jp/d... |
KEGG 05211 | View Gene Set | 0.002648 | 70 | 0.01206 | 47 | Renal cell carcinoma | www.genome.jp/d... |
KEGG 03020 | View Gene Set | 0.002712 | 29 | 0.01209 | 48 | RNA polymerase | www.genome.jp/d... |
KEGG 00563 | View Gene Set | 0.003276 | 25 | 0.01431 | 49 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | www.genome.jp/d... |
KEGG 00100 | View Gene Set | 0.003345 | 17 | 0.01432 | 50 | Steroid biosynthesis | www.genome.jp/d... |
KEGG 00620 | View Gene Set | 0.003783 | 40 | 0.01587 | 51 | Pyruvate metabolism | www.genome.jp/d... |
KEGG 00860 | View Gene Set | 0.004205 | 43 | 0.0173 | 52 | Porphyrin and chlorophyll metabolism | www.genome.jp/d... |
KEGG 04910 | View Gene Set | 0.004545 | 137 | 0.01835 | 53 | Insulin signaling pathway | www.genome.jp/d... |
KEGG 00280 | View Gene Set | 0.005516 | 44 | 0.02186 | 54 | Valine leucine and isoleucine degradation | www.genome.jp/d... |
KEGG 00010 | View Gene Set | 0.006019 | 64 | 0.02342 | 55 | Glycolysis / Gluconeogenesis | www.genome.jp/d... |
KEGG 05218 | View Gene Set | 0.006714 | 71 | 0.02566 | 56 | Melanoma | www.genome.jp/d... |
KEGG 04722 | View Gene Set | 0.007652 | 126 | 0.02873 | 57 | Neurotrophin signaling pathway | www.genome.jp/d... |
KEGG 03440 | View Gene Set | 0.008096 | 28 | 0.02987 | 58 | Homologous recombination | www.genome.jp/d... |
KEGG 00750 | View Gene Set | 0.008914 | 6 | 0.03233 | 59 | Vitamin B6 metabolism | www.genome.jp/d... |
KEGG 00450 | View Gene Set | 0.01025 | 26 | 0.03656 | 60 | Selenoamino acid metabolism | www.genome.jp/d... |
KEGG 05110 | View Gene Set | 0.01129 | 56 | 0.0396 | 61 | Vibrio cholerae infection | www.genome.jp/d... |
KEGG 00640 | View Gene Set | 0.01447 | 33 | 0.04994 | 62 | Propanoate metabolism | www.genome.jp/d... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
GO GO:0044424 | View Gene Set | 3.815e-180 | 10976 | 5.097e-176 | 1 | intracellular part | amigo.geneontol... |
GO GO:0005622 | View Gene Set | 6.531e-176 | 11329 | 4.363e-172 | 2 | intracellular | amigo.geneontol... |
GO GO:0043227 | View Gene Set | 2.36e-171 | 8383 | 1.051e-167 | 3 | membrane-bounded organelle | amigo.geneontol... |
GO GO:0043231 | View Gene Set | 8.14e-171 | 8376 | 2.719e-167 | 4 | intracellular membrane-bounded organelle | amigo.geneontol... |
GO GO:0043229 | View Gene Set | 4.472e-160 | 9346 | 1.195e-156 | 5 | intracellular organelle | amigo.geneontol... |
GO GO:0043226 | View Gene Set | 5.205e-159 | 9360 | 1.159e-155 | 6 | organelle | amigo.geneontol... |
GO GO:0005737 | View Gene Set | 5.201e-131 | 7676 | 9.926e-128 | 7 | cytoplasm | amigo.geneontol... |
GO GO:0044446 | View Gene Set | 7.073e-126 | 5019 | 1.181e-122 | 8 | intracellular organelle part | amigo.geneontol... |
GO GO:0044422 | View Gene Set | 2.206e-122 | 5089 | 3.275e-119 | 9 | organelle part | amigo.geneontol... |
GO GO:0044444 | View Gene Set | 4.017e-118 | 5184 | 5.367e-115 | 10 | cytoplasmic part | amigo.geneontol... |
GO GO:0070013 | View Gene Set | 2.803e-104 | 1845 | 3.405e-101 | 11 | intracellular organelle lumen | amigo.geneontol... |
GO GO:0031974 | View Gene Set | 1.181e-101 | 1917 | 1.314e-98 | 12 | membrane-enclosed lumen | amigo.geneontol... |
GO GO:0043233 | View Gene Set | 2.75e-100 | 1881 | 2.826e-97 | 13 | organelle lumen | amigo.geneontol... |
GO GO:0044237 | View Gene Set | 3.505e-96 | 7431 | 3.344e-93 | 14 | cellular metabolic process | amigo.geneontol... |
GO GO:0044428 | View Gene Set | 6.967e-94 | 1938 | 6.205e-91 | 15 | nuclear part | amigo.geneontol... |
GO GO:0005634 | View Gene Set | 3.773e-86 | 5198 | 3.151e-83 | 16 | nucleus | amigo.geneontol... |
GO GO:0044260 | View Gene Set | 2.855e-82 | 5699 | 2.243e-79 | 17 | cellular macromolecule metabolic process | amigo.geneontol... |
GO GO:0030529 | View Gene Set | 2.425e-81 | 504 | 1.8e-78 | 18 | ribonucleoprotein complex | amigo.geneontol... |
GO GO:0031981 | View Gene Set | 4.527e-81 | 1518 | 3.183e-78 | 19 | nuclear lumen | amigo.geneontol... |
GO GO:0008152 | View Gene Set | 1.811e-74 | 8439 | 1.21e-71 | 20 | metabolic process | amigo.geneontol... |
GO GO:0005739 | View Gene Set | 1.675e-73 | 1274 | 1.066e-70 | 21 | mitochondrion | amigo.geneontol... |
GO GO:0044464 | View Gene Set | 2.993e-73 | 15066 | 1.818e-70 | 22 | cell part | amigo.geneontol... |
GO GO:0005623 | View Gene Set | 3.608e-73 | 15067 | 2.096e-70 | 23 | cell | amigo.geneontol... |
GO GO:0032991 | View Gene Set | 4.917e-71 | 3237 | 2.737e-68 | 24 | macromolecular complex | amigo.geneontol... |
GO GO:0044238 | View Gene Set | 3.79e-70 | 7629 | 2.026e-67 | 25 | primary metabolic process | amigo.geneontol... |
GO GO:0003723 | View Gene Set | 6.895e-70 | 732 | 3.543e-67 | 26 | RNA binding | amigo.geneontol... |
GO GO:0043170 | View Gene Set | 5.938e-62 | 6274 | 2.938e-59 | 27 | macromolecule metabolic process | amigo.geneontol... |
GO GO:0006412 | View Gene Set | 1.573e-60 | 412 | 7.506e-58 | 28 | translation | amigo.geneontol... |
GO GO:0044267 | View Gene Set | 3.55e-57 | 2465 | 1.635e-54 | 29 | cellular protein metabolic process | amigo.geneontol... |
GO GO:0006396 | View Gene Set | 1.401e-54 | 578 | 6.237e-52 | 30 | RNA processing | amigo.geneontol... |
GO GO:0005654 | View Gene Set | 7.906e-52 | 939 | 3.407e-49 | 31 | nucleoplasm | amigo.geneontol... |
GO GO:0009987 | View Gene Set | 1.403e-51 | 11620 | 5.858e-49 | 32 | cellular process | amigo.geneontol... |
GO GO:0005515 | View Gene Set | 3.009e-51 | 8146 | 1.218e-48 | 33 | protein binding | amigo.geneontol... |
GO GO:0034641 | View Gene Set | 2.203e-49 | 4584 | 8.657e-47 | 34 | cellular nitrogen compound metabolic process | amigo.geneontol... |
GO GO:0010467 | View Gene Set | 1.771e-47 | 3806 | 6.761e-45 | 35 | gene expression | amigo.geneontol... |
GO GO:0006807 | View Gene Set | 4.955e-47 | 4698 | 1.839e-44 | 36 | nitrogen compound metabolic process | amigo.geneontol... |
GO GO:0005840 | View Gene Set | 8.643e-47 | 198 | 3.121e-44 | 37 | ribosome | amigo.geneontol... |
GO GO:0006139 | View Gene Set | 6.457e-46 | 4294 | 2.27e-43 | 38 | nucleobase nucleoside nucleotide and nucleic acid metabolic process | amigo.geneontol... |
GO GO:0005488 | View Gene Set | 9.731e-46 | 12334 | 3.333e-43 | 39 | binding | amigo.geneontol... |
GO GO:0090304 | View Gene Set | 1.391e-45 | 3724 | 4.645e-43 | 40 | nucleic acid metabolic process | amigo.geneontol... |
GO GO:0005730 | View Gene Set | 1.349e-44 | 734 | 4.397e-42 | 41 | nucleolus | amigo.geneontol... |
GO GO:0003824 | View Gene Set | 4.752e-43 | 5198 | 1.512e-40 | 42 | catalytic activity | amigo.geneontol... |
GO GO:0043228 | View Gene Set | 6.161e-43 | 2690 | 1.871e-40 | 43 | non-membrane-bounded organelle | amigo.geneontol... |
GO GO:0043232 | View Gene Set | 6.161e-43 | 2690 | 1.871e-40 | 43 | intracellular non-membrane-bounded organelle | amigo.geneontol... |
GO GO:0044429 | View Gene Set | 8.639e-42 | 619 | 2.565e-39 | 45 | mitochondrial part | amigo.geneontol... |
GO GO:0005829 | View Gene Set | 1.732e-40 | 1323 | 5.03e-38 | 46 | cytosol | amigo.geneontol... |
GO GO:0003676 | View Gene Set | 1.133e-39 | 2979 | 3.221e-37 | 47 | nucleic acid binding | amigo.geneontol... |
GO GO:0044249 | View Gene Set | 1.447e-39 | 4326 | 4.029e-37 | 48 | cellular biosynthetic process | amigo.geneontol... |
GO GO:0005575 | View Gene Set | 1.874e-39 | 16391 | 5.11e-37 | 49 | cellular_component | amigo.geneontol... |
GO GO:0009058 | View Gene Set | 2.988e-38 | 4436 | 7.984e-36 | 50 | biosynthetic process | amigo.geneontol... |
GO GO:0003735 | View Gene Set | 1.927e-37 | 158 | 5.048e-35 | 51 | structural constituent of ribosome | amigo.geneontol... |
GO GO:0031967 | View Gene Set | 3.894e-37 | 672 | 1e-34 | 52 | organelle envelope | amigo.geneontol... |
GO GO:0031090 | View Gene Set | 7.505e-37 | 1905 | 1.892e-34 | 53 | organelle membrane | amigo.geneontol... |
GO GO:0019538 | View Gene Set | 2.576e-36 | 2935 | 6.373e-34 | 54 | protein metabolic process | amigo.geneontol... |
GO GO:0003674 | View Gene Set | 2.693e-36 | 15462 | 6.541e-34 | 55 | molecular_function | amigo.geneontol... |
GO GO:0022613 | View Gene Set | 5.922e-36 | 194 | 1.413e-33 | 56 | ribonucleoprotein complex biogenesis | amigo.geneontol... |
GO GO:0031975 | View Gene Set | 7.148e-36 | 685 | 1.675e-33 | 57 | envelope | amigo.geneontol... |
GO GO:0034645 | View Gene Set | 5.79e-35 | 3529 | 1.334e-32 | 58 | cellular macromolecule biosynthetic process | amigo.geneontol... |
GO GO:0009059 | View Gene Set | 6.176e-32 | 3597 | 1.398e-29 | 59 | macromolecule biosynthetic process | amigo.geneontol... |
GO GO:0008150 | View Gene Set | 1.765e-31 | 14318 | 3.929e-29 | 60 | biological_process | amigo.geneontol... |
GO GO:0016071 | View Gene Set | 6.398e-31 | 381 | 1.401e-28 | 61 | mRNA metabolic process | amigo.geneontol... |
GO GO:0008380 | View Gene Set | 1.372e-30 | 300 | 2.957e-28 | 62 | RNA splicing | amigo.geneontol... |
GO GO:0033279 | View Gene Set | 1.668e-30 | 121 | 3.538e-28 | 63 | ribosomal subunit | amigo.geneontol... |
GO GO:0043234 | View Gene Set | 1.831e-30 | 2680 | 3.822e-28 | 64 | protein complex | amigo.geneontol... |
GO GO:0046907 | View Gene Set | 7.401e-30 | 753 | 1.521e-27 | 65 | intracellular transport | amigo.geneontol... |
GO GO:0005740 | View Gene Set | 7.698e-29 | 444 | 1.558e-26 | 66 | mitochondrial envelope | amigo.geneontol... |
GO GO:0031966 | View Gene Set | 5.175e-28 | 420 | 1.032e-25 | 67 | mitochondrial membrane | amigo.geneontol... |
GO GO:0034660 | View Gene Set | 1.578e-27 | 236 | 3.101e-25 | 68 | ncRNA metabolic process | amigo.geneontol... |
GO GO:0006414 | View Gene Set | 1.627e-27 | 104 | 3.15e-25 | 69 | translational elongation | amigo.geneontol... |
GO GO:0007049 | View Gene Set | 3.065e-27 | 1006 | 5.85e-25 | 70 | cell cycle | amigo.geneontol... |
GO GO:0042254 | View Gene Set | 5.539e-27 | 130 | 1.028e-24 | 71 | ribosome biogenesis | amigo.geneontol... |
GO GO:0044451 | View Gene Set | 5.533e-27 | 600 | 1.028e-24 | 71 | nucleoplasm part | amigo.geneontol... |
GO GO:0044265 | View Gene Set | 5.826e-27 | 479 | 1.066e-24 | 73 | cellular macromolecule catabolic process | amigo.geneontol... |
GO GO:0032446 | View Gene Set | 1.55e-26 | 310 | 2.798e-24 | 74 | protein modification by small protein conjugation | amigo.geneontol... |
GO GO:0006259 | View Gene Set | 1.673e-26 | 592 | 2.98e-24 | 75 | DNA metabolic process | amigo.geneontol... |
GO GO:0070647 | View Gene Set | 2.19e-26 | 356 | 3.851e-24 | 76 | protein modification by small protein conjugation or removal | amigo.geneontol... |
GO GO:0034470 | View Gene Set | 1.552e-25 | 193 | 2.693e-23 | 77 | ncRNA processing | amigo.geneontol... |
GO GO:0006397 | View Gene Set | 2.26e-25 | 317 | 3.87e-23 | 78 | mRNA processing | amigo.geneontol... |
GO GO:0016070 | View Gene Set | 2.376e-25 | 2596 | 4.018e-23 | 79 | RNA metabolic process | amigo.geneontol... |
GO GO:0000166 | View Gene Set | 2.854e-25 | 2257 | 4.766e-23 | 80 | nucleotide binding | amigo.geneontol... |
GO GO:0009057 | View Gene Set | 5.26e-25 | 570 | 8.676e-23 | 81 | macromolecule catabolic process | amigo.geneontol... |
GO GO:0045184 | View Gene Set | 1.05e-24 | 904 | 1.71e-22 | 82 | establishment of protein localization | amigo.geneontol... |
GO GO:0015031 | View Gene Set | 1.205e-24 | 888 | 1.939e-22 | 83 | protein transport | amigo.geneontol... |
GO GO:0016567 | View Gene Set | 6.839e-24 | 286 | 1.088e-21 | 84 | protein ubiquitination | amigo.geneontol... |
GO GO:0008104 | View Gene Set | 1.181e-23 | 1048 | 1.856e-21 | 85 | protein localization | amigo.geneontol... |
GO GO:0006996 | View Gene Set | 6.753e-23 | 1501 | 1.049e-20 | 86 | organelle organization | amigo.geneontol... |
GO GO:0006974 | View Gene Set | 1.23e-22 | 412 | 1.889e-20 | 87 | response to DNA damage stimulus | amigo.geneontol... |
GO GO:0005694 | View Gene Set | 1.986e-21 | 507 | 3.015e-19 | 88 | chromosome | amigo.geneontol... |
GO GO:0019866 | View Gene Set | 3.195e-21 | 334 | 4.797e-19 | 89 | organelle inner membrane | amigo.geneontol... |
GO GO:0033036 | View Gene Set | 4.472e-21 | 1256 | 6.639e-19 | 90 | macromolecule localization | amigo.geneontol... |
GO GO:0044445 | View Gene Set | 6.847e-21 | 148 | 1.005e-18 | 91 | cytosolic part | amigo.geneontol... |
GO GO:0006457 | View Gene Set | 9.651e-21 | 172 | 1.401e-18 | 92 | protein folding | amigo.geneontol... |
GO GO:0044085 | View Gene Set | 1.727e-20 | 1167 | 2.481e-18 | 93 | cellular component biogenesis | amigo.geneontol... |
GO GO:0005759 | View Gene Set | 3.173e-20 | 223 | 4.462e-18 | 94 | mitochondrial matrix | amigo.geneontol... |
GO GO:0031980 | View Gene Set | 3.173e-20 | 223 | 4.462e-18 | 94 | mitochondrial lumen | amigo.geneontol... |
GO GO:0000278 | View Gene Set | 3.641e-20 | 489 | 5.067e-18 | 96 | mitotic cell cycle | amigo.geneontol... |
GO GO:0022402 | View Gene Set | 5.419e-20 | 676 | 7.463e-18 | 97 | cell cycle process | amigo.geneontol... |
GO GO:0019941 | View Gene Set | 5.94e-20 | 302 | 8.016e-18 | 98 | modification-dependent protein catabolic process | amigo.geneontol... |
GO GO:0043632 | View Gene Set | 5.94e-20 | 302 | 8.016e-18 | 98 | modification-dependent macromolecule catabolic process | amigo.geneontol... |
GO GO:0022626 | View Gene Set | 6.77e-20 | 75 | 9.045e-18 | 100 | cytosolic ribosome | amigo.geneontol... |
GO GO:0005743 | View Gene Set | 8.323e-20 | 305 | 1.101e-17 | 101 | mitochondrial inner membrane | amigo.geneontol... |
GO GO:0006364 | View Gene Set | 1.234e-19 | 97 | 1.617e-17 | 102 | rRNA processing | amigo.geneontol... |
GO GO:0006511 | View Gene Set | 1.892e-19 | 296 | 2.451e-17 | 103 | ubiquitin-dependent protein catabolic process | amigo.geneontol... |
GO GO:0016072 | View Gene Set | 1.908e-19 | 101 | 2.451e-17 | 103 | rRNA metabolic process | amigo.geneontol... |
GO GO:0016874 | View Gene Set | 4.044e-19 | 436 | 5.146e-17 | 105 | ligase activity | amigo.geneontol... |
GO GO:0005783 | View Gene Set | 5.998e-19 | 1024 | 7.56e-17 | 106 | endoplasmic reticulum | amigo.geneontol... |
GO GO:0030163 | View Gene Set | 6.085e-19 | 398 | 7.597e-17 | 107 | protein catabolic process | amigo.geneontol... |
GO GO:0051603 | View Gene Set | 6.191e-19 | 346 | 7.659e-17 | 108 | proteolysis involved in cellular protein catabolic process | amigo.geneontol... |
GO GO:0044257 | View Gene Set | 7.18e-19 | 349 | 8.8e-17 | 109 | cellular protein catabolic process | amigo.geneontol... |
GO GO:0044432 | View Gene Set | 9.848e-19 | 689 | 1.196e-16 | 110 | endoplasmic reticulum part | amigo.geneontol... |
GO GO:0051276 | View Gene Set | 1.801e-18 | 548 | 2.168e-16 | 111 | chromosome organization | amigo.geneontol... |
GO GO:0010498 | View Gene Set | 2.544e-18 | 166 | 3.034e-16 | 112 | proteasomal protein catabolic process | amigo.geneontol... |
GO GO:0016604 | View Gene Set | 2.654e-18 | 198 | 3.138e-16 | 113 | nuclear body | amigo.geneontol... |
GO GO:0044248 | View Gene Set | 3.08e-18 | 1005 | 3.609e-16 | 114 | cellular catabolic process | amigo.geneontol... |
GO GO:0006281 | View Gene Set | 4.911e-18 | 309 | 5.705e-16 | 115 | DNA repair | amigo.geneontol... |
GO GO:0043161 | View Gene Set | 1.113e-17 | 162 | 1.282e-15 | 116 | proteasomal ubiquitin-dependent protein catabolic process | amigo.geneontol... |
GO GO:0000375 | View Gene Set | 1.26e-17 | 106 | 1.439e-15 | 117 | RNA splicing via transesterification reactions | amigo.geneontol... |
GO GO:0071212 | View Gene Set | 1.518e-17 | 723 | 1.718e-15 | 118 | subsynaptic reticulum | amigo.geneontol... |
GO GO:0043933 | View Gene Set | 1.577e-17 | 836 | 1.77e-15 | 119 | macromolecular complex subunit organization | amigo.geneontol... |
GO GO:0033554 | View Gene Set | 3.128e-17 | 698 | 3.482e-15 | 120 | cellular response to stress | amigo.geneontol... |
GO GO:0006886 | View Gene Set | 3.172e-17 | 439 | 3.503e-15 | 121 | intracellular protein transport | amigo.geneontol... |
GO GO:0015934 | View Gene Set | 3.214e-17 | 64 | 3.52e-15 | 122 | large ribosomal subunit | amigo.geneontol... |
GO GO:0065003 | View Gene Set | 3.408e-17 | 763 | 3.702e-15 | 123 | macromolecular complex assembly | amigo.geneontol... |
GO GO:0070727 | View Gene Set | 3.836e-17 | 503 | 4.133e-15 | 124 | cellular macromolecule localization | amigo.geneontol... |
GO GO:0044427 | View Gene Set | 6.945e-17 | 420 | 7.423e-15 | 125 | chromosomal part | amigo.geneontol... |
GO GO:0005789 | View Gene Set | 8.864e-17 | 622 | 9.399e-15 | 126 | endoplasmic reticulum membrane | amigo.geneontol... |
GO GO:0034613 | View Gene Set | 9.082e-17 | 501 | 9.554e-15 | 127 | cellular protein localization | amigo.geneontol... |
GO GO:0042175 | View Gene Set | 1.475e-16 | 637 | 1.539e-14 | 128 | nuclear membrane-endoplasmic reticulum network | amigo.geneontol... |
GO GO:0005681 | View Gene Set | 2.774e-16 | 135 | 2.873e-14 | 129 | spliceosomal complex | amigo.geneontol... |
GO GO:0000377 | View Gene Set | 2.84e-16 | 97 | 2.897e-14 | 130 | RNA splicing via transesterification reactions with bulged adenosine as nucleophile | amigo.geneontol... |
GO GO:0000398 | View Gene Set | 2.84e-16 | 97 | 2.897e-14 | 130 | nuclear mRNA splicing via spliceosome | amigo.geneontol... |
GO GO:0006260 | View Gene Set | 4.079e-16 | 239 | 4.128e-14 | 132 | DNA replication | amigo.geneontol... |
GO GO:0015935 | View Gene Set | 4.672e-16 | 59 | 4.693e-14 | 133 | small ribosomal subunit | amigo.geneontol... |
GO GO:0016568 | View Gene Set | 1.939e-15 | 324 | 1.933e-13 | 134 | chromatin modification | amigo.geneontol... |
GO GO:0022403 | View Gene Set | 2.298e-15 | 522 | 2.274e-13 | 135 | cell cycle phase | amigo.geneontol... |
GO GO:0044419 | View Gene Set | 3.563e-15 | 343 | 3.5e-13 | 136 | interspecies interaction between organisms | amigo.geneontol... |
GO GO:0006091 | View Gene Set | 4.87e-15 | 339 | 4.749e-13 | 137 | generation of precursor metabolites and energy | amigo.geneontol... |
GO GO:0034621 | View Gene Set | 5.827e-15 | 458 | 5.641e-13 | 138 | cellular macromolecular complex subunit organization | amigo.geneontol... |
GO GO:0044455 | View Gene Set | 9.617e-15 | 133 | 9.243e-13 | 139 | mitochondrial membrane part | amigo.geneontol... |
GO GO:0008135 | View Gene Set | 1.115e-14 | 86 | 1.064e-12 | 140 | translation factor activity nucleic acid binding | amigo.geneontol... |
GO GO:0051301 | View Gene Set | 2.02e-14 | 358 | 1.914e-12 | 141 | cell division | amigo.geneontol... |
GO GO:0010608 | View Gene Set | 2.214e-14 | 247 | 2.083e-12 | 142 | posttranscriptional regulation of gene expression | amigo.geneontol... |
GO GO:0048285 | View Gene Set | 2.823e-14 | 286 | 2.638e-12 | 143 | organelle fission | amigo.geneontol... |
GO GO:0009056 | View Gene Set | 3.512e-14 | 1255 | 3.259e-12 | 144 | catabolic process | amigo.geneontol... |
GO GO:0022618 | View Gene Set | 3.814e-14 | 76 | 3.514e-12 | 145 | ribonucleoprotein complex assembly | amigo.geneontol... |
GO GO:0000087 | View Gene Set | 7.214e-14 | 286 | 6.557e-12 | 146 | M phase of mitotic cell cycle | amigo.geneontol... |
GO GO:0000279 | View Gene Set | 7.211e-14 | 406 | 6.557e-12 | 146 | M phase | amigo.geneontol... |
GO GO:0000280 | View Gene Set | 9.273e-14 | 276 | 8.314e-12 | 148 | nuclear division | amigo.geneontol... |
GO GO:0007067 | View Gene Set | 9.273e-14 | 276 | 8.314e-12 | 148 | mitosis | amigo.geneontol... |
GO GO:0006399 | View Gene Set | 9.787e-14 | 118 | 8.717e-12 | 150 | tRNA metabolic process | amigo.geneontol... |
GO GO:0031396 | View Gene Set | 1.06e-13 | 121 | 9.374e-12 | 151 | regulation of protein ubiquitination | amigo.geneontol... |
GO GO:0012505 | View Gene Set | 1.601e-13 | 1454 | 1.407e-11 | 152 | endomembrane system | amigo.geneontol... |
GO GO:0051082 | View Gene Set | 2.38e-13 | 113 | 2.078e-11 | 153 | unfolded protein binding | amigo.geneontol... |
GO GO:0006325 | View Gene Set | 2.88e-13 | 425 | 2.499e-11 | 154 | chromatin organization | amigo.geneontol... |
GO GO:0051438 | View Gene Set | 3.615e-13 | 82 | 3.116e-11 | 155 | regulation of ubiquitin-protein ligase activity | amigo.geneontol... |
GO GO:0043412 | View Gene Set | 5.278e-13 | 1848 | 4.52e-11 | 156 | macromolecule modification | amigo.geneontol... |
GO GO:0031398 | View Gene Set | 5.737e-13 | 95 | 4.882e-11 | 157 | positive regulation of protein ubiquitination | amigo.geneontol... |
GO GO:0016879 | View Gene Set | 5.834e-13 | 273 | 4.933e-11 | 158 | ligase activity forming carbon-nitrogen bonds | amigo.geneontol... |
GO GO:0016740 | View Gene Set | 6.436e-13 | 1691 | 5.408e-11 | 159 | transferase activity | amigo.geneontol... |
GO GO:0034622 | View Gene Set | 7.965e-13 | 393 | 6.651e-11 | 160 | cellular macromolecular complex assembly | amigo.geneontol... |
GO GO:0051649 | View Gene Set | 8.778e-13 | 1116 | 7.284e-11 | 161 | establishment of localization in cell | amigo.geneontol... |
GO GO:0017076 | View Gene Set | 9.085e-13 | 1934 | 7.492e-11 | 162 | purine nucleotide binding | amigo.geneontol... |
GO GO:0060255 | View Gene Set | 9.834e-13 | 3411 | 8.061e-11 | 163 | regulation of macromolecule metabolic process | amigo.geneontol... |
GO GO:0051641 | View Gene Set | 1.166e-12 | 1206 | 9.501e-11 | 164 | cellular localization | amigo.geneontol... |
GO GO:0016043 | View Gene Set | 1.288e-12 | 2937 | 1.043e-10 | 165 | cellular component organization | amigo.geneontol... |
GO GO:0006417 | View Gene Set | 1.48e-12 | 151 | 1.191e-10 | 166 | regulation of translation | amigo.geneontol... |
GO GO:0005819 | View Gene Set | 1.702e-12 | 167 | 1.362e-10 | 167 | spindle | amigo.geneontol... |
GO GO:0051340 | View Gene Set | 2.214e-12 | 85 | 1.761e-10 | 168 | regulation of ligase activity | amigo.geneontol... |
GO GO:0019787 | View Gene Set | 2.348e-12 | 210 | 1.856e-10 | 169 | small conjugating protein ligase activity | amigo.geneontol... |
GO GO:0006413 | View Gene Set | 3.238e-12 | 62 | 2.545e-10 | 170 | translational initiation | amigo.geneontol... |
GO GO:0032553 | View Gene Set | 4.843e-12 | 1851 | 3.762e-10 | 171 | ribonucleotide binding | amigo.geneontol... |
GO GO:0032555 | View Gene Set | 4.843e-12 | 1851 | 3.762e-10 | 171 | purine ribonucleotide binding | amigo.geneontol... |
GO GO:0051246 | View Gene Set | 5.109e-12 | 652 | 3.924e-10 | 173 | regulation of protein metabolic process | amigo.geneontol... |
GO GO:0016853 | View Gene Set | 5.11e-12 | 132 | 3.924e-10 | 173 | isomerase activity | amigo.geneontol... |
GO GO:0051443 | View Gene Set | 5.545e-12 | 71 | 4.233e-10 | 175 | positive regulation of ubiquitin-protein ligase activity | amigo.geneontol... |
GO GO:0000775 | View Gene Set | 6.596e-12 | 146 | 5.007e-10 | 176 | chromosome centromeric region | amigo.geneontol... |
GO GO:0032268 | View Gene Set | 7.097e-12 | 576 | 5.357e-10 | 177 | regulation of cellular protein metabolic process | amigo.geneontol... |
GO GO:0006839 | View Gene Set | 8.864e-12 | 75 | 6.653e-10 | 178 | mitochondrial transport | amigo.geneontol... |
GO GO:0008565 | View Gene Set | 1.001e-11 | 85 | 7.468e-10 | 179 | protein transporter activity | amigo.geneontol... |
GO GO:0006464 | View Gene Set | 1.179e-11 | 1768 | 8.75e-10 | 180 | protein modification process | amigo.geneontol... |
GO GO:0000502 | View Gene Set | 1.372e-11 | 63 | 1.013e-09 | 181 | proteasome complex | amigo.geneontol... |
GO GO:0051439 | View Gene Set | 1.465e-11 | 68 | 1.075e-09 | 182 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | amigo.geneontol... |
GO GO:0003743 | View Gene Set | 1.932e-11 | 52 | 1.41e-09 | 183 | translation initiation factor activity | amigo.geneontol... |
GO GO:0022900 | View Gene Set | 2.353e-11 | 115 | 1.709e-09 | 184 | electron transport chain | amigo.geneontol... |
GO GO:0001882 | View Gene Set | 2.554e-11 | 1630 | 1.844e-09 | 185 | nucleoside binding | amigo.geneontol... |
GO GO:0000313 | View Gene Set | 2.863e-11 | 49 | 2.045e-09 | 186 | organellar ribosome | amigo.geneontol... |
GO GO:0005761 | View Gene Set | 2.863e-11 | 49 | 2.045e-09 | 186 | mitochondrial ribosome | amigo.geneontol... |
GO GO:0008134 | View Gene Set | 3.495e-11 | 525 | 2.484e-09 | 188 | transcription factor binding | amigo.geneontol... |
GO GO:0051351 | View Gene Set | 3.567e-11 | 74 | 2.522e-09 | 189 | positive regulation of ligase activity | amigo.geneontol... |
GO GO:0010605 | View Gene Set | 3.648e-11 | 827 | 2.565e-09 | 190 | negative regulation of macromolecule metabolic process | amigo.geneontol... |
GO GO:0022625 | View Gene Set | 4.041e-11 | 36 | 2.827e-09 | 191 | cytosolic large ribosomal subunit | amigo.geneontol... |
GO GO:0001883 | View Gene Set | 4.35e-11 | 1620 | 3.027e-09 | 192 | purine nucleoside binding | amigo.geneontol... |
GO GO:0006605 | View Gene Set | 4.704e-11 | 273 | 3.256e-09 | 193 | protein targeting | amigo.geneontol... |
GO GO:0016607 | View Gene Set | 5.276e-11 | 116 | 3.633e-09 | 194 | nuclear speck | amigo.geneontol... |
GO GO:0048037 | View Gene Set | 5.333e-11 | 249 | 3.654e-09 | 195 | cofactor binding | amigo.geneontol... |
GO GO:0051437 | View Gene Set | 6.114e-11 | 64 | 4.167e-09 | 196 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | amigo.geneontol... |
GO GO:0005635 | View Gene Set | 7.196e-11 | 234 | 4.88e-09 | 197 | nuclear envelope | amigo.geneontol... |
GO GO:0030530 | View Gene Set | 7.838e-11 | 17 | 5.289e-09 | 198 | heterogeneous nuclear ribonucleoprotein complex | amigo.geneontol... |
GO GO:0006626 | View Gene Set | 8.223e-11 | 32 | 5.493e-09 | 199 | protein targeting to mitochondrion | amigo.geneontol... |
GO GO:0070585 | View Gene Set | 8.223e-11 | 32 | 5.493e-09 | 199 | protein localization in mitochondrion | amigo.geneontol... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | View Gene Set | 2.723e-147 | 1353 | 6.514e-144 | 1 | Genes up-regulated in CD34+ [Gene ID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients compared to those from normal donors. | www.broad.mit.e... |
Broad PUJANA_BRCA1_PCC_NETWORK | View Gene Set | 2.94e-130 | 1582 | 3.517e-127 | 2 | Genes constituting the BRCA1-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA1 [Gene ID=672] across a compendium of normal tissues. | www.broad.mit.e... |
Broad CAIRO_HEPATOBLASTOMA_CLASSES_UP | View Gene Set | 7.391e-117 | 577 | 5.893e-114 | 3 | Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). | www.broad.mit.e... |
Broad PUJANA_CHEK2_PCC_NETWORK | View Gene Set | 7.391e-111 | 744 | 4.42e-108 | 4 | Genes constituting the CHEK2-PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient PCC >= 0.4) with that of CHEK2 [Gene ID=11200]. | www.broad.mit.e... |
Broad DODD_NASOPHARYNGEAL_CARCINOMA_DN | View Gene Set | 3.557e-99 | 1253 | 1.702e-96 | 5 | Genes down-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. | www.broad.mit.e... |
Broad KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP | View Gene Set | 5.043e-82 | 1180 | 2.01e-79 | 6 | Genes up-regulated in TC71 and EWS502 cells (Ewing's sarcoma) upon knockdown of the EWSR1-FLII fusion [Gene ID=2130 2314]. | www.broad.mit.e... |
Broad HSIAO_HOUSEKEEPING_GENES | View Gene Set | 3.434e-75 | 384 | 1.173e-72 | 7 | Housekeeping genes identified as expressed across 19 normal tissues. | www.broad.mit.e... |
Broad TIEN_INTESTINE_PROBIOTICS_24HR_UP | View Gene Set | 5.636e-73 | 537 | 1.685e-70 | 8 | Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h. | www.broad.mit.e... |
Broad WEI_MYCN_TARGETS_WITH_E_BOX | View Gene Set | 1.082e-64 | 757 | 2.876e-62 | 9 | Genes whose promoters contain E-box motifs and whose expression changed in MYCN-3 cells (neuroblastoma) upon induction of MYCN [Gene ID=4613]. | www.broad.mit.e... |
Broad ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP | View Gene Set | 4.194e-64 | 806 | 1.003e-61 | 10 | Genes up-regulated in liver tumor compared to the normal adjacent tissue. | www.broad.mit.e... |
Broad WONG_EMBRYONIC_STEM_CELL_CORE | View Gene Set | 1.995e-63 | 331 | 4.339e-61 | 11 | The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module. | www.broad.mit.e... |
Broad DANG_BOUND_BY_MYC | View Gene Set | 2.891e-63 | 1045 | 5.763e-61 | 12 | Genes whose promoters are bound by MYC [Gene ID=4609] according to MYC Target Gene Database. | www.broad.mit.e... |
Broad GRADE_COLON_CANCER_UP | View Gene Set | 7.436e-62 | 711 | 1.368e-59 | 13 | Up-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples. | www.broad.mit.e... |
Broad BLALOCK_ALZHEIMERS_DISEASE_DN | View Gene Set | 1.25e-59 | 1209 | 2.136e-57 | 14 | Genes down-regulated in brain from patients with Alzheimer's disease. | www.broad.mit.e... |
Broad ACEVEDO_LIVER_CANCER_UP | View Gene Set | 2.221e-58 | 915 | 3.542e-56 | 15 | Genes up-regulated in hepatocellular carcinoma (HCC) compared to normal liver samples. | www.broad.mit.e... |
Broad CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | View Gene Set | 3.599e-58 | 639 | 5.38e-56 | 16 | Genes down-regulated in APL (acute promyeolocytic leukemia) blasts expressing PML-RARA fusion [Gene ID=5371 5914] compared to normal promyeloblasts. | www.broad.mit.e... |
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN | View Gene Set | 5.645e-57 | 920 | 7.943e-55 | 17 | Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h. | www.broad.mit.e... |
Broad BENPORATH_MYC_MAX_TARGETS | View Gene Set | 6.931e-57 | 768 | 9.21e-55 | 18 | Set 'Myc targets2': targets of c-Myc [Gene ID=4609] and Max [Gene ID=4149] identified by ChIP on chip in a Burkitt???s lymphoma cell line; overlap set. | www.broad.mit.e... |
Broad RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN | View Gene Set | 1.379e-56 | 351 | 1.736e-54 | 19 | Genes down-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids. | www.broad.mit.e... |
Broad NUYTTEN_EZH2_TARGETS_DN | View Gene Set | 2.063e-56 | 859 | 2.467e-54 | 20 | Genes down-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [Gene ID=2146] by RNAi. | www.broad.mit.e... |
Broad SHEN_SMARCA2_TARGETS_UP | View Gene Set | 5.219e-56 | 406 | 5.945e-54 | 21 | Genes whose expression positively correlated with that of SMARCA2 [Gene ID=6595] in prostate cancer samples. | www.broad.mit.e... |
Broad BORCZUK_MALIGNANT_MESOTHELIOMA_UP | View Gene Set | 6.111e-54 | 290 | 6.644e-52 | 22 | Genes up-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma. | www.broad.mit.e... |
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP | View Gene Set | 1.365e-51 | 469 | 1.42e-49 | 23 | Genes up-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. | www.broad.mit.e... |
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | View Gene Set | 2.792e-50 | 589 | 2.782e-48 | 24 | Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. | www.broad.mit.e... |
Broad SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN | View Gene Set | 4.66e-49 | 571 | 4.459e-47 | 25 | Genes down-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. | www.broad.mit.e... |
Broad SCHLOSSER_SERUM_RESPONSE_DN | View Gene Set | 1.235e-47 | 666 | 1.136e-45 | 26 | Cluster 4: genes down-regulated in B493-6 cells (B lymphocytes) upon serum stimulation but not affected by MYC [Gene ID=4609]. | www.broad.mit.e... |
Broad ENK_UV_RESPONSE_KERATINOCYTE_DN | View Gene Set | 4.128e-47 | 475 | 3.657e-45 | 27 | Genes down-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation. | www.broad.mit.e... |
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN | View Gene Set | 8.664e-47 | 832 | 7.402e-45 | 28 | Genes down-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. | www.broad.mit.e... |
Broad MANALO_HYPOXIA_DN | View Gene Set | 2.226e-43 | 276 | 1.836e-41 | 29 | Genes down-regulated in response to both hypoxia and overexpression of an active form of HIF1A [Gene ID=3091]. | www.broad.mit.e... |
Broad MITSIADES_RESPONSE_TO_APLIDIN_DN | View Gene Set | 4.48e-43 | 241 | 3.572e-41 | 30 | Genes down-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164] a marine-derived compound with potential anti-cancer properties. | www.broad.mit.e... |
Broad PUJANA_ATM_PCC_NETWORK | View Gene Set | 2.808e-42 | 1375 | 2.166e-40 | 31 | Genes constituting the ATM-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of ATM [Gene ID=472] across a compendium of normal tissues. | www.broad.mit.e... |
Broad BERENJENO_TRANSFORMED_BY_RHOA_UP | View Gene Set | 3.143e-42 | 485 | 2.349e-40 | 32 | Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [Gene ID=387] off plasmid vector. | www.broad.mit.e... |
Broad SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM | View Gene Set | 1.531e-41 | 154 | 1.11e-39 | 33 | Cluster 7: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] and down-regulated by the combination of MYC and serum. | www.broad.mit.e... |
Broad MOOTHA_MITOCHONDRIA | View Gene Set | 2.648e-41 | 433 | 1.863e-39 | 34 | Mitochondrial genes | www.broad.mit.e... |
Broad BENPORATH_CYCLING_GENES | View Gene Set | 1.001e-40 | 630 | 6.839e-39 | 35 | Genes showing cell-cycle stage-specific expression [PMID=12058064]. | www.broad.mit.e... |
Broad LOPEZ_MBD_TARGETS | View Gene Set | 1.477e-40 | 855 | 9.814e-39 | 36 | Genes up-regulated in HeLa cells (cervical cancer) after simultaneus knockdown of all three MBD (methyl-CpG binding domain) proteins MeCP2 MBD1 and MBD2 [Gene ID=4204 4152 8932] by RNAi. | www.broad.mit.e... |
Broad SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 | View Gene Set | 1.604e-40 | 435 | 1.037e-38 | 37 | Cluster 6 of method A: up-regulation of these genes in patients with non???small cell lung cancer (NSCLC) predicts poor survival outcome. | www.broad.mit.e... |
Broad MOOTHA_HUMAN_MITODB_6_2002 | View Gene Set | 3.244e-39 | 420 | 2.042e-37 | 38 | Mitochondrial genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. | www.broad.mit.e... |
Broad FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | View Gene Set | 3.679e-39 | 532 | 2.256e-37 | 39 | Genes diffierentially expressed in kidney biopsies from patients with well functioning kidneys more than 1-year post transplant compared to the biopsies from normal living kidney donors. | www.broad.mit.e... |
Broad GARY_CD5_TARGETS_DN | View Gene Set | 4.117e-39 | 415 | 2.462e-37 | 40 | Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. | www.broad.mit.e... |
Broad MUELLER_PLURINET | View Gene Set | 6.31e-39 | 294 | 3.682e-37 | 41 | Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells embryonical carcinomas and induced pluripotent cells). | www.broad.mit.e... |
Broad ZHANG_BREAST_CANCER_PROGENITORS_UP | View Gene Set | 9.167e-39 | 370 | 5.221e-37 | 42 | Genes changed in cancer stem cells isolated from mammary tumors compared to the non-tumorigenic cells. | www.broad.mit.e... |
Broad BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP | View Gene Set | 1.06e-38 | 184 | 5.896e-37 | 43 | Up-regulated genes in hepatocellular carcinoma (HCC) subclass G3 defined by unsupervised clustering. | www.broad.mit.e... |
Broad PUJANA_BRCA2_PCC_NETWORK | View Gene Set | 2.475e-38 | 410 | 1.345e-36 | 44 | Genes constituting the BRCA2-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient PCC >= 0.4) with that of BRCA2 [Gene ID=675] across a compendium of normal tissues. | www.broad.mit.e... |
Broad TARTE_PLASMA_CELL_VS_PLASMABLAST_DN | View Gene Set | 3.954e-37 | 303 | 2.102e-35 | 45 | Genes down-regulated in mature plasma cells compared with plasmablastic B lymphocytes. | www.broad.mit.e... |
Broad MILI_PSEUDOPODIA_HAPTOTAXIS_UP | View Gene Set | 3.001e-36 | 452 | 1.561e-34 | 46 | Transcripts enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin FN1 [Gene ID=2335]. | www.broad.mit.e... |
Broad BIDUS_METASTASIS_UP | View Gene Set | 1.497e-35 | 203 | 7.621e-34 | 47 | Genes up-regulated in endometroid endometrial tumors from patients with lymph node metastases compared to those without the metastases. | www.broad.mit.e... |
Broad STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN | View Gene Set | 6.426e-35 | 437 | 3.202e-33 | 48 | Genes down-regulated in prefrontal cortex (PFC) of mice carrying a hemizygotic microdeletion in the 22q11.2 region. | www.broad.mit.e... |
Broad BENPORATH_NANOG_TARGETS | View Gene Set | 4.259e-34 | 946 | 2.079e-32 | 49 | Set 'Nanog targets': genes upregulated and identified by ChIP on chip as Nanog [Gene ID=79923] transcription factor targets in human embryonic stem cells. | www.broad.mit.e... |
Broad LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN | View Gene Set | 6.73e-34 | 742 | 3.22e-32 | 50 | Genes with copy number losses in primary neuroblastoma tumors. | www.broad.mit.e... |
Broad WONG_MITOCHONDRIA_GENE_MODULE | View Gene Set | 1.927e-32 | 208 | 9.036e-31 | 51 | Genes that comprise the mitochondria gene module | www.broad.mit.e... |
Broad FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | View Gene Set | 2.565e-32 | 265 | 1.18e-30 | 52 | Genes identified by method 2 as coordinately down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro. | www.broad.mit.e... |
Broad MOHANKUMAR_TLX1_TARGETS_UP | View Gene Set | 8.044e-31 | 388 | 3.63e-29 | 53 | Up-regulated in MCF7 cells (breast cancer) by TLX1 (HOX11) [Gene ID=3195]. | www.broad.mit.e... |
Broad RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | View Gene Set | 9.461e-31 | 681 | 4.191e-29 | 54 | Genes up-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue. | www.broad.mit.e... |
Broad LIU_SOX4_TARGETS_DN | View Gene Set | 2.955e-30 | 297 | 1.285e-28 | 55 | Genes down-regulated in LNCaP cells (prostate cancer) by overexpression of SOX4 [Gene ID=6659] and up-regulated by its RNAi knockdown. | www.broad.mit.e... |
Broad SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP | View Gene Set | 5.852e-30 | 143 | 2.5e-28 | 56 | Up-regulated genes whose expression correlated with histologic grade of invasive breast cancer tumors: comparison of grade 1 vs grade 3. | www.broad.mit.e... |
Broad FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | View Gene Set | 2.132e-29 | 532 | 8.947e-28 | 57 | Genes differentially expressed in kidney biopsies from patients with acute transplant rejection compared to the biopsies from patients with well functioning kidneys more than 1-year post transplant. | www.broad.mit.e... |
Broad ONKEN_UVEAL_MELANOMA_UP | View Gene Set | 2.794e-29 | 739 | 1.152e-27 | 58 | Genes up-regulated in uveal melanoma: class 2 vs class 1 tumors. | www.broad.mit.e... |
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 | View Gene Set | 8.938e-29 | 165 | 3.624e-27 | 59 | Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 17. | www.broad.mit.e... |
Broad DANG_MYC_TARGETS_UP | View Gene Set | 1.604e-28 | 127 | 6.396e-27 | 60 | Genes up-regulated by MYC [Gene ID=4609] and whose promoters are bound by MYC according to MYC Target Gene Database. | www.broad.mit.e... |
Broad TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C | View Gene Set | 2.047e-28 | 436 | 8.025e-27 | 61 | Genes down-regulated in HCT116 cells (colon cancer) upon expression of MIR34B or MIR34C [Gene ID=407041 407042] microRNAs. | www.broad.mit.e... |
Broad BLUM_RESPONSE_TO_SALIRASIB_DN | View Gene Set | 4.357e-28 | 332 | 1.681e-26 | 62 | Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [Gene ID=3265]. | www.broad.mit.e... |
Broad TIEN_INTESTINE_PROBIOTICS_24HR_DN | View Gene Set | 4.438e-28 | 208 | 1.685e-26 | 63 | Genes down-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h. | www.broad.mit.e... |
Broad HORIUCHI_WTAP_TARGETS_DN | View Gene Set | 4.86e-28 | 289 | 1.816e-26 | 64 | Genes down-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [Gene ID=9589] by RNAi. | www.broad.mit.e... |
Broad MILI_PSEUDOPODIA_HAPTOTAXIS_DN | View Gene Set | 1.522e-27 | 607 | 5.603e-26 | 65 | Transcripts depleted from pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin FN1 [Gene ID=2335]. | www.broad.mit.e... |
Broad MOOTHA_PGC | View Gene Set | 1.661e-27 | 329 | 6.021e-26 | 66 | Genes up-regulated in differentiating C2C12 cells (myoblasts) upon expression of PPARGC1A [Gene ID=10891] off an adenoviral vector. | www.broad.mit.e... |
Broad NUYTTEN_NIPP1_TARGETS_DN | View Gene Set | 2.647e-27 | 758 | 9.451e-26 | 67 | Genes down-regulated in PC3 cells (prostate cancer) after knockdown of NIPP1 [Gene ID=5511] by RNAi. | www.broad.mit.e... |
Broad BENPORATH_SOX2_TARGETS | View Gene Set | 2.867e-27 | 704 | 1.009e-25 | 68 | Set 'Sox2 targets': genes upregulated and identified by ChIP on chip as SOX2 [Gene ID=6657] transcription factor targets in human embryonic stem cells. | www.broad.mit.e... |
Broad BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | View Gene Set | 3.189e-27 | 599 | 1.105e-25 | 69 | Genes down-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress. | www.broad.mit.e... |
Broad GRADE_COLON_AND_RECTAL_CANCER_UP | View Gene Set | 1.231e-26 | 213 | 4.206e-25 | 70 | Up-regulated genes in both rectal and colon carcinoma compared to normal mucosa samples. | www.broad.mit.e... |
Broad CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN | View Gene Set | 1.327e-26 | 155 | 4.471e-25 | 71 | Marker genes down-regulated in the 'unannotated' subclass of hepatocellular carcinoma (HCC) samples. | www.broad.mit.e... |
Broad KOBAYASHI_EGFR_SIGNALING_24HR_DN | View Gene Set | 2.498e-26 | 243 | 8.3e-25 | 72 | Genes down-regulated in H1975 cells (non-small cell lung cancer NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 24h. | www.broad.mit.e... |
Broad LINDGREN_BLADDER_CANCER_CLUSTER_3_UP | View Gene Set | 5.033e-26 | 314 | 1.649e-24 | 73 | Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors. | www.broad.mit.e... |
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | View Gene Set | 7.539e-26 | 825 | 2.437e-24 | 74 | Genes down-regulated in fibroblasts expressing mutant forms of ERCC3 [Gene ID=2071] after UV irradiation. | www.broad.mit.e... |
Broad WEST_ADRENOCORTICAL_TUMOR_UP | View Gene Set | 1.497e-25 | 283 | 4.773e-24 | 75 | Up-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue. | www.broad.mit.e... |
Broad ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER | View Gene Set | 2.006e-25 | 138 | 6.313e-24 | 76 | The 'Cervical Cancer Proliferation Cluster' (CCPC): genes whose expression in cervical carcinoma positively correlates with that of the HPV E6 and E7 oncogenes; they are also differentially expressed according to disease outcome. | www.broad.mit.e... |
Broad BENPORATH_PROLIFERATION | View Gene Set | 7.815e-25 | 140 | 2.428e-23 | 77 | Set 'Proliferation Cluster': genes defined in human breast tumor expression data. | www.broad.mit.e... |
Broad PUJANA_XPRSS_INT_NETWORK | View Gene Set | 8.458e-25 | 164 | 2.594e-23 | 78 | Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200] in a compendium of normal tissues. | www.broad.mit.e... |
Broad RAMALHO_STEMNESS_UP | View Gene Set | 2.001e-24 | 192 | 6.06e-23 | 79 | Genes enriched in embryonic neural and hematopoietic stem cells. | www.broad.mit.e... |
Broad DAIRKEE_TERT_TARGETS_UP | View Gene Set | 2.943e-24 | 317 | 8.8e-23 | 80 | Genes up-regulated in non-spontaneously immortalizing (NSI) primary breast cancer tumor cultures upon expression of TERT [Gene ID=7015] off a retroviral vector. | www.broad.mit.e... |
Broad VECCHI_GASTRIC_CANCER_EARLY_UP | View Gene Set | 1.678e-23 | 408 | 4.956e-22 | 81 | Up-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. | www.broad.mit.e... |
Broad GARY_CD5_TARGETS_UP | View Gene Set | 2.246e-23 | 463 | 6.551e-22 | 82 | Genes up-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [Gene ID=921] off a plasmid vector. | www.broad.mit.e... |
Broad WINNEPENNINCKX_MELANOMA_METASTASIS_UP | View Gene Set | 5.711e-23 | 152 | 1.646e-21 | 83 | Genes from the 254-gene classifier which were up-regulated in melanoma patients with a reported distant metastasis within 4 years. | www.broad.mit.e... |
Broad BLALOCK_ALZHEIMERS_DISEASE_UP | View Gene Set | 6.078e-23 | 1641 | 1.731e-21 | 84 | Genes up-regulated in brain from patients with Alzheimer's disease. | www.broad.mit.e... |
Broad BLUM_RESPONSE_TO_SALIRASIB_UP | View Gene Set | 8.135e-23 | 240 | 2.289e-21 | 85 | Selected genes up-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [Gene ID=3265]. | www.broad.mit.e... |
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 | View Gene Set | 1.86e-22 | 158 | 5.173e-21 | 86 | Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 13. | www.broad.mit.e... |
Broad PAL_PRMT5_TARGETS_UP | View Gene Set | 2.067e-22 | 178 | 5.682e-21 | 87 | Genes up-regulated in NIH-3T3 cells (fibroblast) after knockdown of PRMT5 [Gene ID=10419] by RNAi. | www.broad.mit.e... |
Broad LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER | View Gene Set | 2.683e-22 | 167 | 7.292e-21 | 88 | Overexpressed genes with amplified copy number across 27 non-small cell lung cancer (NSCLC) cell lines. | www.broad.mit.e... |
Broad OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | View Gene Set | 5.431e-22 | 114 | 1.46e-20 | 89 | Genes up-regulated in epithelial ovarian cancer (EOC) biopsies: invasive (TOV) vs low malignant potential (LMP) tumors. | www.broad.mit.e... |
Broad KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | View Gene Set | 1.699e-21 | 869 | 4.515e-20 | 90 | Genes up-regulated in HL-60 cells (acute promyelocytic leukemia APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. | www.broad.mit.e... |
Broad STEIN_ESRRA_TARGETS | View Gene Set | 2.013e-21 | 508 | 5.292e-20 | 91 | Genes regulated by ESRRA [Gene ID=2101] in MCF-7 cells (breast cancer). | www.broad.mit.e... |
Broad ONKEN_UVEAL_MELANOMA_DN | View Gene Set | 2.233e-21 | 509 | 5.806e-20 | 92 | Genes down-regulated in uveal melanoma: class 2 vs class 1 tumors. | www.broad.mit.e... |
Broad LI_AMPLIFIED_IN_LUNG_CANCER | View Gene Set | 4.541e-21 | 165 | 1.168e-19 | 93 | Genes with increased copy number that correlates with increased expression across six different lung adenocarcinoma cell lines. | www.broad.mit.e... |
Broad KIM_WT1_TARGETS_DN | View Gene Set | 4.68e-21 | 431 | 1.191e-19 | 94 | Genes down-regulated in UB27 cells (osteosarcoma) at any time point after inducing the expression of a mutant form of WT1 [Gene ID=7490]. | www.broad.mit.e... |
Broad MARKEY_RB1_ACUTE_LOF_DN | View Gene Set | 1.066e-20 | 201 | 2.683e-19 | 95 | Genes down-regulated in adult fibroblasts with inactivated RB1 [Gene ID=5925] by Cre-lox: acute loss of function (LOF) of RB1. | www.broad.mit.e... |
Broad CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | View Gene Set | 1.908e-20 | 422 | 4.755e-19 | 96 | Genes up-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. | www.broad.mit.e... |
Broad JISON_SICKLE_CELL_DISEASE_DN | View Gene Set | 3.365e-20 | 168 | 8.299e-19 | 97 | Genes down-regulated in peripheral blood mononuclear cells (PBMC) from sickle cell disease patients compared to those from healthy subjects. | www.broad.mit.e... |
Broad GOLDRATH_HOMEOSTATIC_PROLIFERATION | View Gene Set | 7.131e-20 | 154 | 1.74e-18 | 98 | Up-regulated in CD8+ [Gene ID=925] T lymphocytes undergoing homeostatic proliferation (HP) versus the naive cells; these genes are not up-regulated versus effector or memory cell population. | www.broad.mit.e... |
Broad OSMAN_BLADDER_CANCER_UP | View Gene Set | 1.155e-19 | 387 | 2.791e-18 | 99 | Genes up-regulated in blood samples from bladder cancer patients. | www.broad.mit.e... |
Broad HAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN | View Gene Set | 2.388e-19 | 111 | 5.712e-18 | 100 | Genes down-regulated in T helper cells (defines as CD4+) isolated from patients with mucosis fungoides compared to those from normal control donors. | www.broad.mit.e... |
Broad PUJANA_BRCA_CENTERED_NETWORK | View Gene Set | 6.802e-19 | 92 | 1.611e-17 | 101 | Genes constituting the BRCA-centered network (BCN). | www.broad.mit.e... |
Broad WANG_LMO4_TARGETS_UP | View Gene Set | 2.021e-18 | 341 | 4.695e-17 | 102 | Genes up-regulated in MCF7 cells (breast cancer) engineered to conditionally express LMO4 [Gene ID=8543] by a Tet Off system. | www.broad.mit.e... |
Broad MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | View Gene Set | 2.022e-18 | 212 | 4.695e-17 | 102 | Genes down-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199]. | www.broad.mit.e... |
Broad WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP | View Gene Set | 2.791e-18 | 244 | 6.418e-17 | 104 | Genes up-regulated in mucinous ovarian carcinoma tumors of low malignant potential (LMP) compared to normal ovarian surface epithelium tissue. | www.broad.mit.e... |
Broad WELCSH_BRCA1_TARGETS_1_DN | View Gene Set | 4.313e-18 | 124 | 9.825e-17 | 105 | Upregulated by induction of exogenous BRCA1 in EcR-293 cells | www.broad.mit.e... |
Broad MISSIAGLIA_REGULATED_BY_METHYLATION_DN | View Gene Set | 6.102e-18 | 96 | 1.377e-16 | 106 | Genes down-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668] a DNA hypomethylating agent similar to azacitidine [PubChem=9444]. | www.broad.mit.e... |
Broad CROONQUIST_IL6_DEPRIVATION_DN | View Gene Set | 7.54e-18 | 80 | 1.686e-16 | 107 | Genes down-regulated in the ANBL-6 cell line (multiple myeloma MM) after withdrawal of IL6 [Gene ID=3569]. | www.broad.mit.e... |
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 | View Gene Set | 8.625e-18 | 131 | 1.893e-16 | 108 | Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 14. | www.broad.mit.e... |
Broad LEE_LIVER_CANCER_SURVIVAL_DN | View Gene Set | 8.584e-18 | 123 | 1.893e-16 | 108 | Genes highly expressed in hepatocellular carcinoma with poor survival. | www.broad.mit.e... |
Broad OSMAN_BLADDER_CANCER_DN | View Gene Set | 1.204e-17 | 358 | 2.619e-16 | 110 | Genes down-regulated in blood samples from bladder cancer patients. | www.broad.mit.e... |
Broad FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | View Gene Set | 1.47e-17 | 147 | 3.168e-16 | 111 | Genes upreglated in peripheral blood lymphocytes (PBL) from patients with well functioning kidneys more than 1-year post transplant compared to those from normal living kidney donors. | www.broad.mit.e... |
Broad KAAB_FAILED_HEART_ATRIUM_DN | View Gene Set | 1.914e-17 | 139 | 4.087e-16 | 112 | Genes down-regulated in atria of failing hearts (DCM and ICM) compared to healthy controls. | www.broad.mit.e... |
Broad GEORGES_TARGETS_OF_MIR192_AND_MIR215 | View Gene Set | 2.003e-17 | 809 | 4.202e-16 | 113 | Genes down-regulated in HCT116 cells (colon cancer) by expression of MIR192 or MIR215 [Gene ID=406967 406997] at 24 h. | www.broad.mit.e... |
Broad LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN | View Gene Set | 1.987e-17 | 158 | 4.202e-16 | 113 | Genes down-regulated in Wilm's tumor samples compared to fetal kidney. | www.broad.mit.e... |
Broad UDAYAKUMAR_MED1_TARGETS_UP | View Gene Set | 2.207e-17 | 129 | 4.59e-16 | 115 | Genes up-regulated in HeLa cells after knockdown of MED1 [Gene ID=5469] by RNAi. | www.broad.mit.e... |
Broad GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP | View Gene Set | 3.883e-17 | 180 | 7.939e-16 | 116 | Genes up-regulated in quiescent CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors compared to the dividing cells from CML (chronic myeloid leukemia) patients. | www.broad.mit.e... |
Broad PENG_GLUTAMINE_DEPRIVATION_DN | View Gene Set | 3.87e-17 | 84 | 7.939e-16 | 116 | Genes down-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation. | www.broad.mit.e... |
Broad BASAKI_YBX1_TARGETS_UP | View Gene Set | 5.723e-17 | 279 | 1.16e-15 | 118 | Genes up-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [Gene ID=4904] knockdown by RNAi. | www.broad.mit.e... |
Broad ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN | View Gene Set | 6.3e-17 | 346 | 1.266e-15 | 119 | Genes down-regulated in normal tissue adjacent to liver tumor compared to the normal liver samples. | www.broad.mit.e... |
Broad WANG_SMARCE1_TARGETS_DN | View Gene Set | 9.2e-17 | 329 | 1.834e-15 | 120 | Genes down-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [Gene ID=6605] off a retroviral vector. | www.broad.mit.e... |
Broad YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_10 | View Gene Set | 1.227e-16 | 63 | 2.426e-15 | 121 | Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 11. | www.broad.mit.e... |
Broad LIU_PROSTATE_CANCER_UP | View Gene Set | 1.491e-16 | 88 | 2.912e-15 | 122 | Genes up-regulated in prostate cancer samples. | www.broad.mit.e... |
Broad RHODES_CANCER_META_SIGNATURE | View Gene Set | 1.497e-16 | 54 | 2.912e-15 | 122 | Genes commonly up-regulated in cancer relative to normal tissue according to the meta-analysis of the OncoMine gene expression database. | www.broad.mit.e... |
Broad KANG_DOXORUBICIN_RESISTANCE_UP | View Gene Set | 1.514e-16 | 53 | 2.92e-15 | 124 | Genes differentialy expressed in gastric cancer cell lines: doxorubicin [PubChem=31703] resistant vs sensitive. | www.broad.mit.e... |
Broad MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP | View Gene Set | 1.545e-16 | 359 | 2.957e-15 | 125 | The postradiation tumor escape signature: genes up-regulated in tumors from irradiated stroma vs those from non-irradiated stroma. | www.broad.mit.e... |
Broad FUJII_YBX1_TARGETS_DN | View Gene Set | 3.164e-16 | 139 | 6.006e-15 | 126 | Genes down-regulated in MCF-7 cells (breast cancer) after knockdown of YBX1 [Gene ID=4904] by RNAi. | www.broad.mit.e... |
Broad STEIN_ESRRA_TARGETS_UP | View Gene Set | 3.344e-16 | 368 | 6.298e-15 | 127 | Genes up-regulated by ESRRA [Gene ID=2101] only. | www.broad.mit.e... |
Broad SEIDEN_ONCOGENESIS_BY_MET | View Gene Set | 4.692e-16 | 83 | 8.769e-15 | 128 | Genes changed in xenograft tumors formed by DLD-1 or DKO-4 cells (colon cancer) overexpressing MET [Gene ID=4233]. | www.broad.mit.e... |
Broad CROONQUIST_NRAS_SIGNALING_DN | View Gene Set | 5.031e-16 | 62 | 9.329e-15 | 129 | Genes down-regulated in ANBL-6 cell line (multiple myeloma MM) expressing a constantly active form of NRAS [Gene ID=4893] off a plasmid vector compared to those grown in the presence of IL6 [Gene ID=3569]. | www.broad.mit.e... |
Broad MILI_PSEUDOPODIA_CHEMOTAXIS_DN | View Gene Set | 6.237e-16 | 430 | 1.148e-14 | 130 | Transcripts depleted in pseudopodia of NIH/3T3 cells (fibroblast) in response to the chemotactic migration stimulus by lysophosphatidic acid (LPA) [PubChem=3988]. | www.broad.mit.e... |
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | View Gene Set | 9.681e-16 | 301 | 1.768e-14 | 131 | Genes up-regulated in fibroblasts expressing mutant forms of ERCC3 [Gene ID=2071] after UV irradiation. | www.broad.mit.e... |
Broad ALONSO_METASTASIS_UP | View Gene Set | 1.671e-15 | 152 | 3.028e-14 | 132 | Up-regulated genes in melanoma tumous that developed metastatic disease compared to primary melanoma that did not. | www.broad.mit.e... |
Broad BASSO_B_LYMPHOCYTE_NETWORK | View Gene Set | 1.701e-15 | 136 | 3.058e-14 | 133 | Genes which comprise the top 1% of highly interconnected genes (major hubs) that account for most of gene interactions in the reconstructed regulatory networks from expression profiles in B lymphocytes. | www.broad.mit.e... |
Broad MOOTHA_VOXPHOS | View Gene Set | 1.831e-15 | 82 | 3.269e-14 | 134 | Genes involved in oxidative phosphorylation; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. | www.broad.mit.e... |
Broad NELSON_RESPONSE_TO_ANDROGEN_UP | View Gene Set | 2.458e-15 | 81 | 4.355e-14 | 135 | Genes up-regulated in LNCaP cells (prostate cancer) in response to synthetic androgen R1881 [PubChem=13766]. | www.broad.mit.e... |
Broad CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP | View Gene Set | 7.384e-15 | 51 | 1.299e-13 | 136 | Protein biosynthesis transport or catabolism genes up-regulated in hyperploid multiple myeloma (MM) compared to the non-hyperploid MM samples. | www.broad.mit.e... |
Broad TIEN_INTESTINE_PROBIOTICS_6HR_UP | View Gene Set | 8.47e-15 | 50 | 1.479e-13 | 137 | Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 6h. | www.broad.mit.e... |
Broad AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP | View Gene Set | 1.009e-14 | 288 | 1.749e-13 | 138 | Up-regulated genes whose expression correlates with copy number gains in pancreatic adenocarcinoma cell lines and primary tumor specimens. | www.broad.mit.e... |
Broad WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP | View Gene Set | 1.089e-14 | 99 | 1.874e-13 | 139 | Genes up-regulated in rectal cancer patients resistant to radiotherapy (non-responders) relative to the sensitive ones (responders). | www.broad.mit.e... |
Broad SWEET_LUNG_CANCER_KRAS_UP | View Gene Set | 1.132e-14 | 436 | 1.935e-13 | 140 | Genes up-regulated in the mouse lung cancer model with mutated KRAS [Gene ID=3845]. | www.broad.mit.e... |
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN | View Gene Set | 1.167e-14 | 46 | 1.979e-13 | 141 | Cluster 6: genes down-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] in combination with serum but not affected by serum alone; they are also up-regulated by MYC alone. | www.broad.mit.e... |
Broad SCHUHMACHER_MYC_TARGETS_UP | View Gene Set | 1.211e-14 | 68 | 2.039e-13 | 142 | Genes up-regulated in P493-6 cells (Burkitt's lymphoma) induced to express MYC [Gene ID=4609]. | www.broad.mit.e... |
Broad BENPORATH_ES_1 | View Gene Set | 1.307e-14 | 367 | 2.186e-13 | 143 | Set 'ES exp1': genes overexpressed in human embryonic stem cells according to 5 or more out of 20 profiling studies. | www.broad.mit.e... |
Broad WHITEFORD_PEDIATRIC_CANCER_MARKERS | View Gene Set | 2.146e-14 | 92 | 3.565e-13 | 144 | Differentially expressed genes in a panel of xenografts representing 8 common pediatric tumors compared to the normal tissues. | www.broad.mit.e... |
Broad HOSHIDA_LIVER_CANCER_SUBCLASS_S2 | View Gene Set | 2.223e-14 | 114 | 3.667e-13 | 145 | Genes from 'subtype S2' signature of hepatocellular carcinoma (HCC): proliferation MYC and AKT1 [Gene ID=4609 207] activation. | www.broad.mit.e... |
Broad ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP | View Gene Set | 4.156e-14 | 166 | 6.809e-13 | 146 | Genes up-regulated in normal tissue adjacent to liver tumor compared to the normal liver samples. | www.broad.mit.e... |
Broad SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP | View Gene Set | 4.287e-14 | 45 | 6.976e-13 | 147 | Cluster 5: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [Gene ID=4609] alone or in combination with serum but not by serum alone. | www.broad.mit.e... |
Broad DITTMER_PTHLH_TARGETS_UP | View Gene Set | 7.539e-14 | 108 | 1.218e-12 | 148 | Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of PTHLH [Gene ID=5744] by RNAi. | www.broad.mit.e... |
Broad HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | View Gene Set | 7.989e-14 | 93 | 1.283e-12 | 149 | Genes up-regulated during differentiation from large pre-BII to small pre-BII lymphocyte. | www.broad.mit.e... |
Broad CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN | View Gene Set | 8.677e-14 | 99 | 1.384e-12 | 150 | Genes down-regulated by 2-methoxyestradiol (2ME2) [PubChem=1573] in the MM.1S cell line (multiple myeloma) sensitive to dexamethasone [PubChem=5743]. | www.broad.mit.e... |
Broad SAKAI_TUMOR_INFILTRATING_MONOCYTES_DN | View Gene Set | 9.729e-14 | 79 | 1.541e-12 | 151 | Selected genes down-regulated in inflammatory monocytes infiltrating hepatocellular carcinoma (HCC). | www.broad.mit.e... |
Broad ELVIDGE_HYPOXIA_DN | View Gene Set | 1.481e-13 | 136 | 2.33e-12 | 152 | Genes down-regulated in MCF7 cells (breast cancer) under hypoxia conditions. | www.broad.mit.e... |
Broad CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | View Gene Set | 1.541e-13 | 491 | 2.41e-12 | 153 | The 'group 1 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [Gene ID=2099 2064]. | www.broad.mit.e... |
Broad FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | View Gene Set | 1.946e-13 | 321 | 3.023e-12 | 154 | Genes which best discriminate between two groups of breast cancer according the status of ESR1 and AR [Gene ID=2099 367]: apocrine (ESR1- AR+) vs basal (ESR1- AR-). | www.broad.mit.e... |
Broad WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | View Gene Set | 2.163e-13 | 131 | 3.337e-12 | 155 | Genes up-regulated in mucinous ovarian carcinoma tumors of grades 1 and 2 compared to the normal ovarian survace epithelium tissue. | www.broad.mit.e... |
Broad SENESE_HDAC1_TARGETS_UP | View Gene Set | 3.14e-13 | 427 | 4.814e-12 | 156 | Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [Gene ID=3065] by RNAi. | www.broad.mit.e... |
Broad GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN | View Gene Set | 3.338e-13 | 86 | 5.086e-12 | 157 | Genes down-regulated in quiescent vs dividing CD34+ [Gene ID=8842] cells isolated from peripheral blood of normal donors. | www.broad.mit.e... |
Broad NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | View Gene Set | 3.909e-13 | 583 | 5.919e-12 | 158 | Down-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone. | www.broad.mit.e... |
Broad KAUFFMANN_DNA_REPAIR_GENES | View Gene Set | 4.077e-13 | 205 | 6.134e-12 | 159 | Genes involved in DNA repair compiled manually by the authors. | www.broad.mit.e... |
Broad PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN | View Gene Set | 4.416e-13 | 49 | 6.603e-12 | 160 | Antigen processing and presentation genes down-regulated in JY cells (B lymphocytes) treated with trichostatin A (TSA) [PubChem=5562]. | www.broad.mit.e... |
Broad PUJANA_BREAST_CANCER_LIT_INT_NETWORK | View Gene Set | 9.113e-13 | 100 | 1.354e-11 | 161 | Genes constituting the LIT-Int network of proteins interacting with breast cancer reference proteins BRCA1 BRCA2 ATM and CHEK2 [Gene ID=672 675 472 11200]; the interactions were manually curated from the literature. | www.broad.mit.e... |
Broad ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN | View Gene Set | 9.435e-13 | 61 | 1.393e-11 | 162 | Genes down-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]. | www.broad.mit.e... |
Broad WELCSH_BRCA1_TARGETS_1_UP | View Gene Set | 9.605e-13 | 171 | 1.41e-11 | 163 | Upregulated by induction of exogenous BRCA1 in EcR-293 cells | www.broad.mit.e... |
Broad MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN | View Gene Set | 9.742e-13 | 121 | 1.421e-11 | 164 | Genes distinguishing in multiple myeloma (MM) samples with lower expression of TACI [Gene ID=23495]. | www.broad.mit.e... |
Broad ZHANG_RESPONSE_TO_CANTHARIDIN_DN | View Gene Set | 1.084e-12 | 60 | 1.572e-11 | 165 | Genes down-regulated in HL-60 cells (promyeloid leukemia) by cantharidin [PubChem=6708701]. | www.broad.mit.e... |
Broad KAUFFMANN_DNA_REPLICATION_GENES | View Gene Set | 1.096e-12 | 128 | 1.58e-11 | 166 | Genes involved in DNA replication compiled manually by the authors. | www.broad.mit.e... |
Broad BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS | View Gene Set | 1.27e-12 | 805 | 1.819e-11 | 167 | Transcripts in hematopoietic stem cells (HSC) which are trans-regulated (i.e. modulated by a QTL (quantitative trait locus) not in a close proximity to the gene). | www.broad.mit.e... |
Broad DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | View Gene Set | 1.334e-12 | 418 | 1.899e-11 | 168 | Common down-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [Gene ID=2071] after UVC irradiation. | www.broad.mit.e... |
Broad ZHAN_MULTIPLE_MYELOMA_PR_UP | View Gene Set | 1.567e-12 | 43 | 2.218e-11 | 169 | Top 50 up-regulated genes in cluster PR of multiple myeloma samples characterized by increased expression of proliferation and cell cycle genes. | www.broad.mit.e... |
Broad RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | View Gene Set | 1.61e-12 | 732 | 2.265e-11 | 170 | Genes down-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. | www.broad.mit.e... |
Broad BENPORATH_MYC_TARGETS_WITH_EBOX | View Gene Set | 1.739e-12 | 229 | 2.433e-11 | 171 | Set 'Myc targets1': targets of c-Myc [Gene ID=4609] identified by ChIP on chip in cultured cell lines focusing on E-box???containing genes; high affinity bound subset | www.broad.mit.e... |
Broad FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN | View Gene Set | 2.022e-12 | 76 | 2.811e-11 | 172 | Top 100 genes positively (UP) and negatively (DN) associated with T-cell acute lymphoblastic leukemia MLL T-ALL) expressing MLL-ENL fusion [Gene ID=4297 4298]. | www.broad.mit.e... |
Broad AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN | View Gene Set | 2.103e-12 | 218 | 2.908e-11 | 173 | Down-regulated genes whose expression correlates with copy number losses in pancreatic adenocarcinoma cell lines and primary tumor specimens. | www.broad.mit.e... |
Broad IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR | View Gene Set | 2.52e-12 | 100 | 3.464e-11 | 174 | Genes in the expression cluster 'Early Progenitors Shared': up-regulated in hematopoietic progenitors from adult bone marrow and from fetal liver. | www.broad.mit.e... |
Broad SESTO_RESPONSE_TO_UV_C0 | View Gene Set | 2.823e-12 | 106 | 3.858e-11 | 175 | Cluster 0: genes changed in primary keratinocytes by UVB irradiation. | www.broad.mit.e... |
Broad NAKAMURA_CANCER_MICROENVIRONMENT_DN | View Gene Set | 2.884e-12 | 45 | 3.92e-11 | 176 | Genes down-regulated in pancreatic cancer cells grown in orthotopic xenograft tumors compared to those grown in vitro. | www.broad.mit.e... |
Broad MORI_LARGE_PRE_BII_LYMPHOCYTE_UP | View Gene Set | 4.63e-12 | 52 | 6.258e-11 | 177 | Up-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Large Pre-BII stage. | www.broad.mit.e... |
Broad VANTVEER_BREAST_CANCER_METASTASIS_DN | View Gene Set | 5.366e-12 | 104 | 7.211e-11 | 178 | Genes whose expression is significantly and negatively correlated with poor breast cancer clinical outcome (defined as developing distant metastases in less than 5 years). | www.broad.mit.e... |
Broad PROVENZANI_METASTASIS_UP | View Gene Set | 5.813e-12 | 188 | 7.769e-11 | 179 | Genes up-regulated in polysomal and total RNA samples from SW480 cells (primary colorectal carcinoma CRC) compared to the SW620 cells (lymph node metastasis from the same individual). | www.broad.mit.e... |
Broad RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP | View Gene Set | 5.969e-12 | 220 | 7.932e-11 | 180 | Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors. | www.broad.mit.e... |
Broad FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP | View Gene Set | 8.663e-12 | 61 | 1.145e-10 | 181 | Genes diffierentially expressed in peripheral blood lymphocytes (PBL) from patients with acute transplant rejection compared to those from patients with well functioning kidneys more than 1-year post transplant. | www.broad.mit.e... |
Broad HAMAI_APOPTOSIS_VIA_TRAIL_UP | View Gene Set | 9.35e-12 | 328 | 1.229e-10 | 182 | Genes up-regulated in T1 cells (primary melanoma sensitive to TRAIL [Gene ID=8743]) compared to G1 cells (metastatic melanoma resistant to TRAIL). | www.broad.mit.e... |
Broad RHODES_UNDIFFERENTIATED_CANCER | View Gene Set | 1.106e-11 | 60 | 1.445e-10 | 183 | Genes commonly up-regulated in undifferentiated cancer relative to well-differentiated cancer based on the meta-analysis of the OncoMine gene expression database. | www.broad.mit.e... |
Broad PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP | View Gene Set | 1.271e-11 | 53 | 1.652e-10 | 184 | The XPRSS-Int network genes up-regulated in breast tumors from patients with germline mutations in BRCA1 [Gene ID=672] compared to those with the wild type allele. | www.broad.mit.e... |
Broad REN_BOUND_BY_E2F | View Gene Set | 1.652e-11 | 47 | 2.136e-10 | 185 | Genes whose promoters were bound by E2F1 [Gene ID=1869] and E2F4 [Gene ID=1874] in the primary fibroblasts WI-38 by ChIP on chip assay. | www.broad.mit.e... |
Broad MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN | View Gene Set | 1.674e-11 | 42 | 2.153e-10 | 186 | Genes down-regulated in normal bone marrow plasma cells (BMPC) compared to polyclonal plasmablasts (PPC) that also distinguished multiple myeloma (MM) samples by expression of levels of TACI [Gene ID=23495]. | www.broad.mit.e... |
Broad SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP | View Gene Set | 1.902e-11 | 45 | 2.433e-10 | 187 | Top 50 up-regulated markers distinguishing diffuse large B-cell lymphoma (DLBCL) from follicular lymphoma (FL) samples. | www.broad.mit.e... |
Broad ENK_UV_RESPONSE_KERATINOCYTE_UP | View Gene Set | 2.646e-11 | 517 | 3.367e-10 | 188 | Genes up-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation. | www.broad.mit.e... |
Broad FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN | View Gene Set | 2.867e-11 | 43 | 3.628e-10 | 189 | Genes down-regulated in MCF-7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4-hydroxytamoxifen raloxifene or ICI 182780 but not by estradiol [PubChem=44959 5035 3478439 5757]. | www.broad.mit.e... |
Broad SCHLOSSER_SERUM_RESPONSE_AUGMENTED_BY_MYC | View Gene Set | 3.383e-11 | 101 | 4.26e-10 | 190 | Cluster 2: genes up-regulated in B493-6 cells (B lymphocytes) by serum alone or in combination with MYC [Gene ID=4609] but not by MYC alone. | www.broad.mit.e... |
Broad SONG_TARGETS_OF_IE86_CMV_PROTEIN | View Gene Set | 5.85e-11 | 49 | 7.326e-10 | 191 | Cellular genes up-regulated in forskin fibroblasts by expression of CMV EI86 protein off an adenovirus vector. | www.broad.mit.e... |
Broad LANDIS_ERBB2_BREAST_TUMORS_324_UP | View Gene Set | 6.876e-11 | 132 | 8.566e-10 | 192 | The 324 genes identified by two analytical methods as changed in the mammary tumors induced by transgenic expression of ERBB2 [Gene ID=2064]. | www.broad.mit.e... |
Broad CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP | View Gene Set | 7.244e-11 | 135 | 8.978e-10 | 193 | Genes up-regulated in CD4+ [Gene ID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]. | www.broad.mit.e... |
Broad WANG_LMO4_TARGETS_DN | View Gene Set | 1.125e-10 | 327 | 1.387e-09 | 194 | Genes down-regulated in MCF7 cells (breast cancer) engineered to conditionally express LMO4 [Gene ID=8543] by a Tet Off system. | www.broad.mit.e... |
Broad LINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q | View Gene Set | 1.314e-10 | 106 | 1.612e-09 | 195 | Genes down-regulated in urothelial cell carcinoma (UCC) tumors with LOH on 9q as compared to the tumors showing retention. | www.broad.mit.e... |
Broad POMEROY_MEDULLOBLASTOMA_PROGNOSIS_DN | View Gene Set | 1.342e-10 | 39 | 1.638e-09 | 196 | Top marker genes in medulloblastoma associated with poor response to treatment (poor outcome). | www.broad.mit.e... |
Broad BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN | View Gene Set | 1.882e-10 | 164 | 2.285e-09 | 197 | Genes down-regulated in patients at the incipient stage of Alzheimer's disease. | www.broad.mit.e... |
Broad SMITH_TERT_TARGETS_UP | View Gene Set | 2.028e-10 | 128 | 2.45e-09 | 198 | Genes consistently up-regulated in HMEC cells (primary mammary epithelium) upon expression of TERT [Gene ID=7015] off a retroviral vector. | www.broad.mit.e... |
Broad PENG_RAPAMYCIN_RESPONSE_DN | View Gene Set | 2.222e-10 | 69 | 2.671e-09 | 199 | Genes down-regulated in BJUB cells (B-lymphoma) in response to rapamycin [PubChem=6610346] treatment. | www.broad.mit.e... |
Broad YAMASHITA_LIVER_CANCER_WITH_EPCAM_UP | View Gene Set | 2.244e-10 | 46 | 2.684e-09 | 200 | Up-regulated genes distinguishing hepatocellular carcinoma (HCC) samples positive for EPCAM [Gene ID=4072] from the negative ones. | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad SA_G1_AND_S_PHASES | View Gene Set | 2.412e-06 | 15 | 0.0001134 | 1 | Cdk2 4 and 6 bind cyclin D in G1 while cdk2/cyclin E promotes the G1/S transition. | www.broad.mit.e... |
Broad SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | View Gene Set | 3.257e-05 | 49 | 0.0007654 | 2 | Genes related to the insulin receptor pathway | www.broad.mit.e... |
Broad SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | View Gene Set | 7.976e-05 | 63 | 0.00125 | 3 | Genes related to PIP3 signaling in cardiac myocytes | www.broad.mit.e... |
Broad ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | View Gene Set | 0.0003155 | 34 | 0.003707 | 4 | PI3K Pathway | www.broad.mit.e... |
Broad SA_PTEN_PATHWAY | View Gene Set | 0.001061 | 16 | 0.009975 | 5 | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. | www.broad.mit.e... |
Broad SA_REG_CASCADE_OF_CYCLIN_EXPR | View Gene Set | 0.001745 | 13 | 0.01367 | 6 | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. | www.broad.mit.e... |
Broad SIG_CHEMOTAXIS | View Gene Set | 0.002747 | 44 | 0.01845 | 7 | Genes related to chemotaxis | www.broad.mit.e... |
Broad ST_G_ALPHA_S_PATHWAY | View Gene Set | 0.005701 | 12 | 0.03349 | 8 | G alpha s Pathway | www.broad.mit.e... |
Broad ST_GA13_PATHWAY | View Gene Set | 0.007895 | 35 | 0.04123 | 9 | G alpha 13 Pathway | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad BIOCARTA_RACCYCD_PATHWAY | View Gene Set | 2.768e-08 | 26 | 6.006e-06 | 1 | Influence of Ras and Rho proteins on G1 to S Transition | www.broad.mit.e... |
Broad BIOCARTA_EIF_PATHWAY | View Gene Set | 4.291e-07 | 16 | 3.954e-05 | 2 | Eukaryotic protein translation | www.broad.mit.e... |
Broad BIOCARTA_MTOR_PATHWAY | View Gene Set | 5.467e-07 | 23 | 3.954e-05 | 2 | mTOR Signaling Pathway | www.broad.mit.e... |
Broad BIOCARTA_PROTEASOME_PATHWAY | View Gene Set | 1.651e-06 | 19 | 8.956e-05 | 4 | Proteasome Complex | www.broad.mit.e... |
Broad BIOCARTA_P27_PATHWAY | View Gene Set | 2.914e-06 | 13 | 0.0001265 | 5 | Regulation of p27 Phosphorylation during Cell Cycle Progression | www.broad.mit.e... |
Broad BIOCARTA_AKAP95_PATHWAY | View Gene Set | 1.57e-05 | 12 | 0.0004868 | 6 | AKAP95 role in mitosis and chromosome dynamics | www.broad.mit.e... |
Broad BIOCARTA_IGF1MTOR_PATHWAY | View Gene Set | 1.498e-05 | 20 | 0.0004868 | 6 | Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway | www.broad.mit.e... |
Broad BIOCARTA_G1_PATHWAY | View Gene Set | 2.648e-05 | 28 | 0.0007183 | 8 | Cell Cycle: G1/S Check Point | www.broad.mit.e... |
Broad BIOCARTA_G2_PATHWAY | View Gene Set | 6.091e-05 | 24 | 0.001469 | 9 | Cell Cycle: G2/M Checkpoint | www.broad.mit.e... |
Broad BIOCARTA_RAS_PATHWAY | View Gene Set | 9.994e-05 | 23 | 0.002169 | 10 | Ras Signaling Pathway | www.broad.mit.e... |
Broad BIOCARTA_ARF_PATHWAY | View Gene Set | 0.0001201 | 17 | 0.002369 | 11 | Tumor Suppressor Arf Inhibits Ribosomal Biogenesis | www.broad.mit.e... |
Broad BIOCARTA_RANMS_PATHWAY | View Gene Set | 0.0001414 | 10 | 0.002556 | 12 | Role of Ran in mitotic spindle regulation | www.broad.mit.e... |
Broad BIOCARTA_EIF4_PATHWAY | View Gene Set | 0.0001825 | 24 | 0.003046 | 13 | Regulation of eIF4e and p70 S6 Kinase | www.broad.mit.e... |
Broad BIOCARTA_IGF1R_PATHWAY | View Gene Set | 0.0001976 | 23 | 0.003063 | 14 | Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation | www.broad.mit.e... |
Broad BIOCARTA_MCM_PATHWAY | View Gene Set | 0.0002328 | 18 | 0.003157 | 15 | CDK Regulation of DNA Replication | www.broad.mit.e... |
Broad BIOCARTA_EIF2_PATHWAY | View Gene Set | 0.0002283 | 11 | 0.003157 | 15 | Regulation of eIF2 | www.broad.mit.e... |
Broad BIOCARTA_CDC42RAC_PATHWAY | View Gene Set | 0.0002823 | 16 | 0.003603 | 17 | Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration | www.broad.mit.e... |
Broad BIOCARTA_RB_PATHWAY | View Gene Set | 0.0003236 | 13 | 0.003901 | 18 | RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage | www.broad.mit.e... |
Broad BIOCARTA_CELLCYCLE_PATHWAY | View Gene Set | 0.0003492 | 23 | 0.003988 | 19 | Cyclins and Cell Cycle Regulation | www.broad.mit.e... |
Broad BIOCARTA_CHREBP2_PATHWAY | View Gene Set | 0.000394 | 42 | 0.004275 | 20 | Regulation And Function Of ChREBP in Liver | www.broad.mit.e... |
Broad BIOCARTA_RHO_PATHWAY | View Gene Set | 0.0006252 | 32 | 0.006461 | 21 | Rho cell motility signaling pathway | www.broad.mit.e... |
Broad BIOCARTA_GLYCOLYSIS_PATHWAY | View Gene Set | 0.000705 | 10 | 0.006954 | 22 | Glycolysis Pathway | www.broad.mit.e... |
Broad BIOCARTA_VDR_PATHWAY | View Gene Set | 0.0009793 | 12 | 0.008631 | 23 | Control of Gene Expression by Vitamin D Receptor | www.broad.mit.e... |
Broad BIOCARTA_ERK_PATHWAY | View Gene Set | 0.0009944 | 28 | 0.008631 | 23 | Erk1/Erk2 Mapk Signaling pathway | www.broad.mit.e... |
Broad BIOCARTA_CREB_PATHWAY | View Gene Set | 0.0009532 | 27 | 0.008631 | 23 | Transcription factor CREB and its extracellular signals | www.broad.mit.e... |
Broad BIOCARTA_MPR_PATHWAY | View Gene Set | 0.00106 | 34 | 0.008847 | 26 | How Progesterone Initiates Oocyte Membrane | www.broad.mit.e... |
Broad BIOCARTA_KREB_PATHWAY | View Gene Set | 0.001223 | 8 | 0.00983 | 27 | The Citric Acid Cycle | www.broad.mit.e... |
Broad BIOCARTA_RNA_PATHWAY | View Gene Set | 0.001705 | 10 | 0.01252 | 28 | Double Stranded RNA Induced Gene Expression | www.broad.mit.e... |
Broad BIOCARTA_AKAPCENTROSOME_PATHWAY | View Gene Set | 0.00173 | 15 | 0.01252 | 28 | Protein Kinase A at the Centrosome | www.broad.mit.e... |
Broad BIOCARTA_ATRBRCA_PATHWAY | View Gene Set | 0.001726 | 21 | 0.01252 | 28 | Role of BRCA1 BRCA2 and ATR in Cancer Susceptibility | www.broad.mit.e... |
Broad BIOCARTA_ECM_PATHWAY | View Gene Set | 0.002055 | 24 | 0.01436 | 31 | Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia | www.broad.mit.e... |
Broad BIOCARTA_EGFR_SMRTE_PATHWAY | View Gene Set | 0.002184 | 11 | 0.01436 | 31 | Map Kinase Inactivation of SMRT Corepressor | www.broad.mit.e... |
Broad BIOCARTA_P53_PATHWAY | View Gene Set | 0.002167 | 16 | 0.01436 | 31 | p53 Signaling Pathway | www.broad.mit.e... |
Broad BIOCARTA_AKAP13_PATHWAY | View Gene Set | 0.002429 | 12 | 0.0155 | 34 | Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation | www.broad.mit.e... |
Broad BIOCARTA_MAPK_PATHWAY | View Gene Set | 0.002598 | 87 | 0.01611 | 35 | MAPKinase Signaling Pathway | www.broad.mit.e... |
Broad BIOCARTA_SRCRPTP_PATHWAY | View Gene Set | 0.003046 | 11 | 0.0171 | 36 | Activation of Src by Protein-tyrosine phosphatase alpha | www.broad.mit.e... |
Broad BIOCARTA_TEL_PATHWAY | View Gene Set | 0.002849 | 18 | 0.0171 | 36 | Telomeres Telomerase Cellular Aging and Immortality | www.broad.mit.e... |
Broad BIOCARTA_TFF_PATHWAY | View Gene Set | 0.003073 | 21 | 0.0171 | 36 | Trefoil Factors Initiate Mucosal Healing | www.broad.mit.e... |
Broad BIOCARTA_VEGF_PATHWAY | View Gene Set | 0.003036 | 29 | 0.0171 | 36 | VEGF Hypoxia and Angiogenesis | www.broad.mit.e... |
Broad BIOCARTA_MCALPAIN_PATHWAY | View Gene Set | 0.003734 | 25 | 0.01976 | 40 | mCalpain and friends in Cell motility | www.broad.mit.e... |
Broad BIOCARTA_PTEN_PATHWAY | View Gene Set | 0.003658 | 18 | 0.01976 | 40 | PTEN dependent cell cycle arrest and apoptosis | www.broad.mit.e... |
Broad BIOCARTA_SKP2E2F_PATHWAY | View Gene Set | 0.003941 | 10 | 0.02036 | 42 | E2F1 Destruction Pathway | www.broad.mit.e... |
Broad BIOCARTA_ACTINY_PATHWAY | View Gene Set | 0.004679 | 20 | 0.02361 | 43 | Y branching of actin filaments | www.broad.mit.e... |
Broad BIOCARTA_WNT_PATHWAY | View Gene Set | 0.005242 | 26 | 0.02585 | 44 | WNT Signaling Pathway | www.broad.mit.e... |
Broad BIOCARTA_BCELLSURVIVAL_PATHWAY | View Gene Set | 0.005666 | 16 | 0.02622 | 45 | B Cell Survival Pathway | www.broad.mit.e... |
Broad BIOCARTA_HCMV_PATHWAY | View Gene Set | 0.005678 | 17 | 0.02622 | 45 | Human Cytomegalovirus and Map Kinase Pathways | www.broad.mit.e... |
Broad BIOCARTA_HER2_PATHWAY | View Gene Set | 0.005547 | 22 | 0.02622 | 45 | Role of ERBB2 in Signal Transduction and Oncology | www.broad.mit.e... |
Broad BIOCARTA_SALMONELLA_PATHWAY | View Gene Set | 0.007047 | 13 | 0.03058 | 48 | How does salmonella hijack a cell | www.broad.mit.e... |
Broad BIOCARTA_PTC1_PATHWAY | View Gene Set | 0.006968 | 11 | 0.03058 | 48 | Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle | www.broad.mit.e... |
Broad BIOCARTA_SARS_PATHWAY | View Gene Set | 0.006811 | 10 | 0.03058 | 48 | The SARS-coronavirus Life Cycle | www.broad.mit.e... |
Broad BIOCARTA_CK1_PATHWAY | View Gene Set | 0.009173 | 17 | 0.03903 | 51 | Regulation of ck1/cdk5 by type 1 glutamate receptors | www.broad.mit.e... |
Broad BIOCARTA_CERAMIDE_PATHWAY | View Gene Set | 0.009434 | 22 | 0.03933 | 52 | Ceramide Signaling Pathway | www.broad.mit.e... |
Broad BIOCARTA_GCR_PATHWAY | View Gene Set | 0.009607 | 20 | 0.03933 | 52 | Corticosteroids and cardioprotection | www.broad.mit.e... |
Broad BIOCARTA_MET_PATHWAY | View Gene Set | 0.01035 | 37 | 0.04161 | 54 | Signaling of Hepatocyte Growth Factor Receptor | www.broad.mit.e... |
Broad BIOCARTA_CCR3_PATHWAY | View Gene Set | 0.01116 | 23 | 0.04333 | 55 | CCR3 signaling in Eosinophils | www.broad.mit.e... |
Broad BIOCARTA_ETC_PATHWAY | View Gene Set | 0.01118 | 12 | 0.04333 | 55 | Electron Transport Reaction in Mitochondria | www.broad.mit.e... |
Broad BIOCARTA_RAB_PATHWAY | View Gene Set | 0.01175 | 12 | 0.04474 | 57 | Rab GTPases Mark Targets In The Endocytotic Machinery | www.broad.mit.e... |
Broad BIOCARTA_P35ALZHEIMERS_PATHWAY | View Gene Set | 0.01223 | 11 | 0.04574 | 58 | Deregulation of CDK5 in Alzheimers Disease | www.broad.mit.e... |
Broad BIOCARTA_CHEMICAL_PATHWAY | View Gene Set | 0.01267 | 22 | 0.04661 | 59 | Apoptotic Signaling in Response to DNA Damage | www.broad.mit.e... |
Broad BIOCARTA_PTDINS_PATHWAY | View Gene Set | 0.01329 | 23 | 0.04727 | 60 | Phosphoinositides and their downstream targets. | www.broad.mit.e... |
Broad BIOCARTA_NKCELLS_PATHWAY | View Gene Set | 0.01312 | 20 | 0.04727 | 60 | Ras-Independent pathway in NK cell-mediated cytotoxicity | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad KEGG_RIBOSOME | View Gene Set | 1.053e-25 | 88 | 1.958e-23 | 1 | Ribosome | www.broad.mit.e... |
Broad KEGG_SPLICEOSOME | View Gene Set | 2.743e-16 | 118 | 2.551e-14 | 2 | Spliceosome | www.broad.mit.e... |
Broad KEGG_CELL_CYCLE | View Gene Set | 1.503e-15 | 128 | 9.316e-14 | 3 | Cell cycle | www.broad.mit.e... |
Broad KEGG_OXIDATIVE_PHOSPHORYLATION | View Gene Set | 3.557e-12 | 135 | 1.654e-10 | 4 | Oxidative phosphorylation | www.broad.mit.e... |
Broad KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS | View Gene Set | 1.292e-10 | 138 | 4.805e-09 | 5 | Ubiquitin mediated proteolysis | www.broad.mit.e... |
Broad KEGG_PYRIMIDINE_METABOLISM | View Gene Set | 1.566e-10 | 98 | 4.856e-09 | 6 | Pyrimidine metabolism | www.broad.mit.e... |
Broad KEGG_HUNTINGTONS_DISEASE | View Gene Set | 2.351e-10 | 185 | 6.248e-09 | 7 | Huntington's disease | www.broad.mit.e... |
Broad KEGG_RNA_DEGRADATION | View Gene Set | 3.206e-10 | 59 | 7.454e-09 | 8 | RNA degradation | www.broad.mit.e... |
Broad KEGG_PARKINSONS_DISEASE | View Gene Set | 3.986e-09 | 133 | 8.239e-08 | 9 | Parkinson's disease | www.broad.mit.e... |
Broad KEGG_ALZHEIMERS_DISEASE | View Gene Set | 5.814e-09 | 169 | 1.081e-07 | 10 | Alzheimer's disease | www.broad.mit.e... |
Broad KEGG_PROTEASOME | View Gene Set | 2.783e-08 | 48 | 4.705e-07 | 11 | Proteasome | www.broad.mit.e... |
Broad KEGG_OOCYTE_MEIOSIS | View Gene Set | 7.883e-08 | 114 | 1.222e-06 | 12 | Oocyte meiosis | www.broad.mit.e... |
Broad KEGG_AMINOACYL_TRNA_BIOSYNTHESIS | View Gene Set | 9.561e-08 | 41 | 1.368e-06 | 13 | Aminoacyl-tRNA biosynthesis | www.broad.mit.e... |
Broad KEGG_PROTEIN_EXPORT | View Gene Set | 2.231e-07 | 24 | 2.964e-06 | 14 | Protein export | www.broad.mit.e... |
Broad KEGG_DNA_REPLICATION | View Gene Set | 3.726e-07 | 36 | 4.62e-06 | 15 | DNA replication | www.broad.mit.e... |
Broad KEGG_NUCLEOTIDE_EXCISION_REPAIR | View Gene Set | 1.498e-06 | 44 | 1.741e-05 | 16 | Nucleotide excision repair | www.broad.mit.e... |
Broad KEGG_CITRATE_CYCLE_TCA_CYCLE | View Gene Set | 1.662e-06 | 32 | 1.819e-05 | 17 | Citrate cycle (TCA cycle) | www.broad.mit.e... |
Broad KEGG_PROSTATE_CANCER | View Gene Set | 2.258e-06 | 89 | 2.333e-05 | 18 | Prostate cancer | www.broad.mit.e... |
Broad KEGG_CHRONIC_MYELOID_LEUKEMIA | View Gene Set | 2.457e-06 | 73 | 2.406e-05 | 19 | Chronic myeloid leukemia | www.broad.mit.e... |
Broad KEGG_BASE_EXCISION_REPAIR | View Gene Set | 1.029e-05 | 35 | 9.116e-05 | 20 | Base excision repair | www.broad.mit.e... |
Broad KEGG_MTOR_SIGNALING_PATHWAY | View Gene Set | 1.01e-05 | 52 | 9.116e-05 | 20 | mTOR signaling pathway | www.broad.mit.e... |
Broad KEGG_CYSTEINE_AND_METHIONINE_METABOLISM | View Gene Set | 2.633e-05 | 34 | 0.0002226 | 22 | Cysteine and methionine metabolism | www.broad.mit.e... |
Broad KEGG_PANCREATIC_CANCER | View Gene Set | 2.764e-05 | 70 | 0.0002235 | 23 | Pancreatic cancer | www.broad.mit.e... |
Broad KEGG_N_GLYCAN_BIOSYNTHESIS | View Gene Set | 3.053e-05 | 46 | 0.0002366 | 24 | N-Glycan biosynthesis | www.broad.mit.e... |
Broad KEGG_SMALL_CELL_LUNG_CANCER | View Gene Set | 6.741e-05 | 84 | 0.0005015 | 25 | Small cell lung cancer | www.broad.mit.e... |
Broad KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION | View Gene Set | 7.407e-05 | 86 | 0.0005299 | 26 | Progesterone-mediated oocyte maturation | www.broad.mit.e... |
Broad KEGG_PEROXISOME | View Gene Set | 9.992e-05 | 78 | 0.0006409 | 27 | Peroxisome | www.broad.mit.e... |
Broad KEGG_APOPTOSIS | View Gene Set | 9.881e-05 | 88 | 0.0006409 | 27 | Apoptosis | www.broad.mit.e... |
Broad KEGG_NON_SMALL_CELL_LUNG_CANCER | View Gene Set | 9.437e-05 | 54 | 0.0006409 | 27 | Non-small cell lung cancer | www.broad.mit.e... |
Broad KEGG_BLADDER_CANCER | View Gene Set | 0.0001514 | 42 | 0.0009388 | 30 | Bladder cancer | www.broad.mit.e... |
Broad KEGG_PURINE_METABOLISM | View Gene Set | 0.0003428 | 157 | 0.002057 | 31 | Purine metabolism | www.broad.mit.e... |
Broad KEGG_MISMATCH_REPAIR | View Gene Set | 0.0004161 | 23 | 0.002419 | 32 | Mismatch repair | www.broad.mit.e... |
Broad KEGG_LYSINE_DEGRADATION | View Gene Set | 0.0004499 | 44 | 0.002471 | 33 | Lysine degradation | www.broad.mit.e... |
Broad KEGG_LYSOSOME | View Gene Set | 0.0004517 | 122 | 0.002471 | 33 | Lysosome | www.broad.mit.e... |
Broad KEGG_ENDOMETRIAL_CANCER | View Gene Set | 0.0004858 | 52 | 0.002582 | 35 | Endometrial cancer | www.broad.mit.e... |
Broad KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION | View Gene Set | 0.0006568 | 44 | 0.003393 | 36 | Vasopressin-regulated water reabsorption | www.broad.mit.e... |
Broad KEGG_ACUTE_MYELOID_LEUKEMIA | View Gene Set | 0.0007613 | 60 | 0.003827 | 37 | Acute myeloid leukemia | www.broad.mit.e... |
Broad KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS | View Gene Set | 0.00167 | 11 | 0.008176 | 38 | Valine leucine and isoleucine biosynthesis | www.broad.mit.e... |
Broad KEGG_GLIOMA | View Gene Set | 0.001772 | 65 | 0.008319 | 39 | Glioma | www.broad.mit.e... |
Broad KEGG_THYROID_CANCER | View Gene Set | 0.001789 | 29 | 0.008319 | 39 | Thyroid cancer | www.broad.mit.e... |
Broad KEGG_ONE_CARBON_POOL_BY_FOLATE | View Gene Set | 0.001855 | 17 | 0.008417 | 41 | One carbon pool by folate | www.broad.mit.e... |
Broad KEGG_ARGININE_AND_PROLINE_METABOLISM | View Gene Set | 0.001947 | 54 | 0.008621 | 42 | Arginine and proline metabolism | www.broad.mit.e... |
Broad KEGG_RENAL_CELL_CARCINOMA | View Gene Set | 0.002648 | 70 | 0.01145 | 43 | Renal cell carcinoma | www.broad.mit.e... |
Broad KEGG_RNA_POLYMERASE | View Gene Set | 0.002712 | 29 | 0.01146 | 44 | RNA polymerase | www.broad.mit.e... |
Broad KEGG_STEROID_BIOSYNTHESIS | View Gene Set | 0.003345 | 17 | 0.01353 | 45 | Steroid biosynthesis | www.broad.mit.e... |
Broad KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS | View Gene Set | 0.003276 | 25 | 0.01353 | 45 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | www.broad.mit.e... |
Broad KEGG_PYRUVATE_METABOLISM | View Gene Set | 0.003783 | 40 | 0.01497 | 47 | Pyruvate metabolism | www.broad.mit.e... |
Broad KEGG_INSULIN_SIGNALING_PATHWAY | View Gene Set | 0.004545 | 137 | 0.01761 | 48 | Insulin signaling pathway | www.broad.mit.e... |
Broad KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION | View Gene Set | 0.005516 | 44 | 0.02094 | 49 | Valine leucine and isoleucine degradation | www.broad.mit.e... |
Broad KEGG_GLYCOLYSIS_GLUCONEOGENESIS | View Gene Set | 0.00604 | 62 | 0.02247 | 50 | Glycolysis / Gluconeogenesis | www.broad.mit.e... |
Broad KEGG_MELANOMA | View Gene Set | 0.006714 | 71 | 0.02449 | 51 | Melanoma | www.broad.mit.e... |
Broad KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM | View Gene Set | 0.006995 | 41 | 0.02502 | 52 | Porphyrin and chlorophyll metabolism | www.broad.mit.e... |
Broad KEGG_NEUROTROPHIN_SIGNALING_PATHWAY | View Gene Set | 0.007652 | 126 | 0.02685 | 53 | Neurotrophin signaling pathway | www.broad.mit.e... |
Broad KEGG_HOMOLOGOUS_RECOMBINATION | View Gene Set | 0.008096 | 28 | 0.02789 | 54 | Homologous recombination | www.broad.mit.e... |
Broad KEGG_SELENOAMINO_ACID_METABOLISM | View Gene Set | 0.01025 | 26 | 0.03405 | 55 | Selenoamino acid metabolism | www.broad.mit.e... |
Broad KEGG_ENDOCYTOSIS | View Gene Set | 0.01013 | 183 | 0.03405 | 55 | Endocytosis | www.broad.mit.e... |
Broad KEGG_VIBRIO_CHOLERAE_INFECTION | View Gene Set | 0.01129 | 56 | 0.03683 | 57 | Vibrio cholerae infection | www.broad.mit.e... |
Broad KEGG_PROPANOATE_METABOLISM | View Gene Set | 0.01447 | 33 | 0.0464 | 58 | Propanoate metabolism | www.broad.mit.e... |
Broad KEGG_PATHWAYS_IN_CANCER | View Gene Set | 0.01499 | 328 | 0.04725 | 59 | Pathways in cancer | www.broad.mit.e... |
Broad KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM | View Gene Set | 0.01627 | 44 | 0.05 | 60 | Amino sugar and nucleotide sugar metabolism | www.broad.mit.e... |
Broad KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | View Gene Set | 0.0164 | 97 | 0.05 | 60 | Fc gamma R-mediated phagocytosis | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad REACTOME_GENE_EXPRESSION | View Gene Set | 3.961e-52 | 415 | 1.703e-49 | 1 | Genes involved in Gene Expression | www.broad.mit.e... |
Broad REACTOME_TRANSLATION | View Gene Set | 1.619e-35 | 120 | 3.48e-33 | 2 | Genes involved in Translation | www.broad.mit.e... |
Broad REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT | View Gene Set | 2.526e-31 | 106 | 2.716e-29 | 3 | Genes involved in GTP hydrolysis and joining of the 60S ribosomal subunit | www.broad.mit.e... |
Broad REACTOME_INFLUENZA_LIFE_CYCLE | View Gene Set | 1.999e-31 | 137 | 2.716e-29 | 3 | Genes involved in Influenza Life Cycle | www.broad.mit.e... |
Broad REACTOME_METABOLISM_OF_PROTEINS | View Gene Set | 3.186e-30 | 215 | 2.74e-28 | 5 | Genes involved in Metabolism of proteins | www.broad.mit.e... |
Broad REACTOME_DIABETES_PATHWAYS | View Gene Set | 3.92e-30 | 383 | 2.81e-28 | 6 | Genes involved in Diabetes pathways | www.broad.mit.e... |
Broad REACTOME_CELL_CYCLE_MITOTIC | View Gene Set | 1.319e-28 | 306 | 8.105e-27 | 7 | Genes involved in Cell Cycle Mitotic | www.broad.mit.e... |
Broad REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS | View Gene Set | 3.299e-28 | 95 | 1.773e-26 | 8 | Genes involved in Formation of a pool of free 40S subunits | www.broad.mit.e... |
Broad REACTOME_PEPTIDE_CHAIN_ELONGATION | View Gene Set | 3.921e-26 | 84 | 1.873e-24 | 9 | Genes involved in Peptide chain elongation | www.broad.mit.e... |
Broad REACTOME_INSULIN_SYNTHESIS_AND_SECRETION | View Gene Set | 1.918e-25 | 129 | 8.249e-24 | 10 | Genes involved in Insulin Synthesis and Secretion | www.broad.mit.e... |
Broad REACTOME_VIRAL_MRNA_TRANSLATION | View Gene Set | 3.18e-25 | 84 | 1.243e-23 | 11 | Genes involved in Viral mRNA Translation | www.broad.mit.e... |
Broad REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | View Gene Set | 8.715e-25 | 100 | 2.974e-23 | 12 | Genes involved in Influenza Viral RNA Transcription and Replication | www.broad.mit.e... |
Broad REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA | View Gene Set | 8.991e-25 | 128 | 2.974e-23 | 12 | Genes involved in Processing of Capped Intron-Containing Pre-mRNA | www.broad.mit.e... |
Broad REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS | View Gene Set | 3.252e-21 | 124 | 9.989e-20 | 14 | Genes involved in Elongation and Processing of Capped Transcripts | www.broad.mit.e... |
Broad REACTOME_MITOTIC_M_M_G1_PHASES | View Gene Set | 4.51e-21 | 157 | 1.293e-19 | 15 | Genes involved in Mitotic M-M/G1 phases | www.broad.mit.e... |
Broad REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT | View Gene Set | 9.53e-21 | 142 | 2.561e-19 | 16 | Genes involved in Formation and Maturation of mRNA Transcript | www.broad.mit.e... |
Broad REACTOME_METABOLISM_OF_RNA | View Gene Set | 4.734e-20 | 95 | 1.197e-18 | 17 | Genes involved in Metabolism of RNA | www.broad.mit.e... |
Broad REACTOME_MRNA_SPLICING | View Gene Set | 1.231e-19 | 97 | 2.94e-18 | 18 | Genes involved in mRNA Splicing | www.broad.mit.e... |
Broad REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION | View Gene Set | 2.438e-18 | 56 | 5.517e-17 | 19 | Genes involved in Translation initiation complex formation | www.broad.mit.e... |
Broad REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | View Gene Set | 4.198e-18 | 101 | 9.025e-17 | 20 | Genes involved in Regulation of gene expression in beta cells | www.broad.mit.e... |
Broad REACTOME_CELL_CYCLE_CHECKPOINTS | View Gene Set | 1.739e-17 | 110 | 3.561e-16 | 21 | Genes involved in Cell Cycle Checkpoints | www.broad.mit.e... |
Broad REACTOME_HIV_INFECTION | View Gene Set | 4.875e-17 | 183 | 9.529e-16 | 22 | Genes involved in HIV Infection | www.broad.mit.e... |
Broad REACTOME_G1_S_TRANSITION | View Gene Set | 5.768e-17 | 102 | 1.078e-15 | 23 | Genes involved in G1/S Transition | www.broad.mit.e... |
Broad REACTOME_S_PHASE | View Gene Set | 6.022e-17 | 103 | 1.079e-15 | 24 | Genes involved in S Phase | www.broad.mit.e... |
Broad REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | View Gene Set | 6.878e-15 | 120 | 1.183e-13 | 25 | Genes involved in Host Interactions of HIV factors | www.broad.mit.e... |
Broad REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | View Gene Set | 8.269e-15 | 49 | 1.368e-13 | 26 | Genes involved in Formation of the ternary complex and subsequently the 43S complex | www.broad.mit.e... |
Broad REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | View Gene Set | 3.701e-14 | 114 | 5.894e-13 | 27 | Genes involved in Regulation of beta-cell development | www.broad.mit.e... |
Broad REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION | View Gene Set | 9.469e-14 | 161 | 1.454e-12 | 28 | Genes involved in Glucose Regulation of Insulin Secretion | www.broad.mit.e... |
Broad REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | View Gene Set | 2.372e-13 | 229 | 3.517e-12 | 29 | Genes involved in Integration of energy metabolism | www.broad.mit.e... |
Broad REACTOME_SYNTHESIS_OF_DNA | View Gene Set | 7.208e-13 | 89 | 1.033e-11 | 30 | Genes involved in Synthesis of DNA | www.broad.mit.e... |
Broad REACTOME_ELECTRON_TRANSPORT_CHAIN | View Gene Set | 1.788e-12 | 75 | 2.481e-11 | 31 | Genes involved in Electron Transport Chain | www.broad.mit.e... |
Broad REACTOME_DNA_REPLICATION_PRE_INITIATION | View Gene Set | 2.035e-12 | 76 | 2.735e-11 | 32 | Genes involved in DNA Replication Pre-Initiation | www.broad.mit.e... |
Broad REACTOME_M_G1_TRANSITION | View Gene Set | 3.789e-12 | 61 | 4.937e-11 | 33 | Genes involved in M/G1 Transition | www.broad.mit.e... |
Broad REACTOME_REGULATION_OF_APC_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE | View Gene Set | 8.298e-12 | 71 | 1.049e-10 | 34 | Genes involved in Regulation of APC/C activators between G1/S and early anaphase | www.broad.mit.e... |
Broad REACTOME_METABOLISM_OF_MRNA | View Gene Set | 4.789e-11 | 45 | 5.884e-10 | 35 | Genes involved in Metabolism of mRNA | www.broad.mit.e... |
Broad REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | View Gene Set | 5.861e-11 | 58 | 7e-10 | 36 | Genes involved in Cyclin E associated events during G1/S transition | www.broad.mit.e... |
Broad REACTOME_CDC20_PHOSPHO_APC_MEDIATED_DEGRADATION_OF_CYCLIN_A | View Gene Set | 7.773e-11 | 63 | 9.034e-10 | 37 | Genes involved in Cdc20:Phospho-APC/C mediated degradation of Cyclin A | www.broad.mit.e... |
Broad REACTOME_SNRNP_ASSEMBLY | View Gene Set | 8.882e-11 | 50 | 1.005e-09 | 38 | Genes involved in snRNP Assembly | www.broad.mit.e... |
Broad REACTOME_MITOTIC_PROMETAPHASE | View Gene Set | 1.367e-10 | 92 | 1.507e-09 | 39 | Genes involved in Mitotic Prometaphase | www.broad.mit.e... |
Broad REACTOME_ORC1_REMOVAL_FROM_CHROMATIN | View Gene Set | 2.261e-10 | 63 | 2.431e-09 | 40 | Genes involved in Orc1 removal from chromatin | www.broad.mit.e... |
Broad REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | View Gene Set | 2.687e-10 | 23 | 2.819e-09 | 41 | Genes involved in Cytosolic tRNA aminoacylation | www.broad.mit.e... |
Broad REACTOME_HIV_LIFE_CYCLE | View Gene Set | 2.909e-10 | 103 | 2.978e-09 | 42 | Genes involved in HIV Life Cycle | www.broad.mit.e... |
Broad REACTOME_METABLISM_OF_NUCLEOTIDES | View Gene Set | 3.158e-10 | 71 | 3.158e-09 | 43 | Genes involved in Metablism of nucleotides | www.broad.mit.e... |
Broad REACTOME_REGULATION_OF_INSULIN_SECRETION | View Gene Set | 3.676e-10 | 212 | 3.592e-09 | 44 | Genes involved in Regulation of Insulin Secretion | www.broad.mit.e... |
Broad REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | View Gene Set | 2.392e-09 | 90 | 2.286e-08 | 45 | Genes involved in Late Phase of HIV Life Cycle | www.broad.mit.e... |
Broad REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21 | View Gene Set | 3.069e-09 | 52 | 2.869e-08 | 46 | Genes involved in SCF(Skp2)-mediated degradation of p2721 | www.broad.mit.e... |
Broad REACTOME_MEMBRANE_TRAFFICKING | View Gene Set | 3.533e-09 | 78 | 3.232e-08 | 47 | Genes involved in Membrane Trafficking | www.broad.mit.e... |
Broad REACTOME_SIGNALING_BY_WNT | View Gene Set | 5.123e-09 | 58 | 4.589e-08 | 48 | Genes involved in Signaling by Wnt | www.broad.mit.e... |
Broad REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC | View Gene Set | 5.653e-09 | 57 | 4.961e-08 | 49 | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C | www.broad.mit.e... |
Broad REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRON_CONTAINING_TRANSCRIPT | View Gene Set | 5.825e-09 | 42 | 5.01e-08 | 50 | Genes involved in Transport of Mature mRNA derived from an Intron-Containing Transcript | www.broad.mit.e... |
Broad REACTOME_STABILIZATION_OF_P53 | View Gene Set | 8.257e-09 | 46 | 6.962e-08 | 51 | Genes involved in Stabilization of p53 | www.broad.mit.e... |
Broad REACTOME_TRNA_AMINOACYLATION | View Gene Set | 9.766e-09 | 40 | 8.076e-08 | 52 | Genes involved in tRNA Aminoacylation | www.broad.mit.e... |
Broad REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX | View Gene Set | 1.016e-08 | 52 | 8.241e-08 | 53 | Genes involved in CDT1 association with the CDC6:ORC:origin complex | www.broad.mit.e... |
Broad REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | View Gene Set | 1.075e-08 | 47 | 8.56e-08 | 54 | Genes involved in Vif-mediated degradation of APOBEC3G | www.broad.mit.e... |
Broad REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE | View Gene Set | 1.2e-08 | 47 | 9.383e-08 | 55 | Genes involved in Regulation of ornithine decarboxylase (ODC) | www.broad.mit.e... |
Broad REACTOME_TRANSCRIPTION | View Gene Set | 2.715e-08 | 188 | 2.084e-07 | 56 | Genes involved in Transcription | www.broad.mit.e... |
Broad REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE | View Gene Set | 2.933e-08 | 43 | 2.212e-07 | 57 | Genes involved in p53-Independent DNA Damage Response | www.broad.mit.e... |
Broad REACTOME_DNA_REPAIR | View Gene Set | 3.31e-08 | 102 | 2.454e-07 | 58 | Genes involved in DNA Repair | www.broad.mit.e... |
Broad REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | View Gene Set | 4.239e-08 | 48 | 3.09e-07 | 59 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 | www.broad.mit.e... |
Broad REACTOME_DEADENYLATION_OF_MRNA | View Gene Set | 6.814e-08 | 21 | 4.883e-07 | 60 | Genes involved in Deadenylation of mRNA | www.broad.mit.e... |
Broad REACTOME_METABOLISM_OF_AMINO_ACIDS | View Gene Set | 7.86e-08 | 162 | 5.541e-07 | 61 | Genes involved in Metabolism of amino acids | www.broad.mit.e... |
Broad REACTOME_REV_MEDIATED_NUCLEAR_EXPORT_OF_HIV1_RNA | View Gene Set | 1.925e-07 | 31 | 1.335e-06 | 62 | Genes involved in Rev-mediated nuclear export of HIV-1 RNA | www.broad.mit.e... |
Broad REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN | View Gene Set | 1.977e-07 | 30 | 1.349e-06 | 63 | Genes involved in Nuclear import of Rev protein | www.broad.mit.e... |
Broad REACTOME_G2_M_CHECKPOINTS | View Gene Set | 2.507e-07 | 43 | 1.684e-06 | 64 | Genes involved in G2/M Checkpoints | www.broad.mit.e... |
Broad REACTOME_VPR_MEDIATED_NUCLEAR_IMPORT_OF_PICS | View Gene Set | 5.346e-07 | 31 | 3.537e-06 | 65 | Genes involved in Vpr-mediated nuclear import of PICs | www.broad.mit.e... |
Broad REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING | View Gene Set | 6.14e-07 | 61 | 4e-06 | 66 | Genes involved in Clathrin derived vesicle budding | www.broad.mit.e... |
Broad REACTOME_DNA_STRAND_ELONGATION | View Gene Set | 7.14e-07 | 31 | 4.582e-06 | 67 | Genes involved in DNA strand elongation | www.broad.mit.e... |
Broad REACTOME_TRANSPORT_OF_THE_SLBP_INDEPENDENT_MATURE_MRNA | View Gene Set | 7.336e-07 | 32 | 4.639e-06 | 68 | Genes involved in Transport of the SLBP independent Mature mRNA | www.broad.mit.e... |
Broad REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | View Gene Set | 7.501e-07 | 29 | 4.674e-06 | 69 | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery | www.broad.mit.e... |
Broad REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION | View Gene Set | 7.787e-07 | 83 | 4.783e-06 | 70 | Genes involved in RNA Polymerase II Transcription | www.broad.mit.e... |
Broad REACTOME_MTOR_SIGNALLING | View Gene Set | 9.047e-07 | 27 | 5.479e-06 | 71 | Genes involved in mTOR signalling | www.broad.mit.e... |
Broad REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | View Gene Set | 1.557e-06 | 29 | 9.297e-06 | 72 | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus | www.broad.mit.e... |
Broad REACTOME_METABOLISM_OF_CARBOHYDRATES | View Gene Set | 2.038e-06 | 119 | 1.201e-05 | 73 | Genes involved in Metabolism of carbohydrates | www.broad.mit.e... |
Broad REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | View Gene Set | 4.197e-06 | 18 | 2.439e-05 | 74 | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates | www.broad.mit.e... |
Broad REACTOME_CITRIC_ACID_CYCLE | View Gene Set | 5.534e-06 | 19 | 3.173e-05 | 75 | Genes involved in Citric acid cycle (TCA cycle) | www.broad.mit.e... |
Broad REACTOME_MRNA_SPLICING_MINOR_PATHWAY | View Gene Set | 8.231e-06 | 38 | 4.657e-05 | 76 | Genes involved in mRNA Splicing - Minor Pathway | www.broad.mit.e... |
Broad REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | View Gene Set | 1.008e-05 | 37 | 5.631e-05 | 77 | Genes involved in Activation of ATR in response to replication stress | www.broad.mit.e... |
Broad REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION | View Gene Set | 1.028e-05 | 33 | 5.665e-05 | 78 | Genes involved in E2F mediated regulation of DNA replication | www.broad.mit.e... |
Broad REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | View Gene Set | 1.241e-05 | 54 | 6.756e-05 | 79 | Genes involved in Golgi Associated Vesicle Biogenesis | www.broad.mit.e... |
Broad REACTOME_PYRUVATE_METABOLISM_AND_TCA_CYCLE | View Gene Set | 1.732e-05 | 36 | 9.31e-05 | 80 | Genes involved in Pyruvate metabolism and TCA cycle | www.broad.mit.e... |
Broad REACTOME_CYCLIN_A1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | View Gene Set | 1.919e-05 | 15 | 0.0001019 | 81 | Genes involved in Cyclin A1 associated events during G2/M transition | www.broad.mit.e... |
Broad REACTOME_APOPTOSIS | View Gene Set | 2.142e-05 | 129 | 0.0001123 | 82 | Genes involved in Apoptosis | www.broad.mit.e... |
Broad REACTOME_E2F_TRANSCRIPTIONAL_TARGETS_AT_G1_S | View Gene Set | 2.773e-05 | 22 | 0.0001437 | 83 | Genes involved in E2F transcriptional targets at G1/S | www.broad.mit.e... |
Broad REACTOME_G2_M_TRANSITION | View Gene Set | 3.352e-05 | 84 | 0.0001716 | 84 | Genes involved in G2/M Transition | www.broad.mit.e... |
Broad REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | View Gene Set | 4.764e-05 | 30 | 0.000241 | 85 | Genes involved in Activation of the pre-replicative complex | www.broad.mit.e... |
Broad REACTOME_GLOBAL_GENOMIC_NER | View Gene Set | 5.229e-05 | 33 | 0.0002614 | 86 | Genes involved in Global Genomic NER (GG-NER) | www.broad.mit.e... |
Broad REACTOME_NUCLEOTIDE_EXCISION_REPAIR | View Gene Set | 5.42e-05 | 49 | 0.0002679 | 87 | Genes involved in Nucleotide Excision Repair | www.broad.mit.e... |
Broad REACTOME_PURINE_METABOLISM | View Gene Set | 6.611e-05 | 30 | 0.000323 | 88 | Genes involved in Purine metabolism | www.broad.mit.e... |
Broad REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | View Gene Set | 6.779e-05 | 29 | 0.0003275 | 89 | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein | www.broad.mit.e... |
Broad REACTOME_EXTENSION_OF_TELOMERES | View Gene Set | 8.006e-05 | 28 | 0.0003825 | 90 | Genes involved in Extension of Telomeres | www.broad.mit.e... |
Broad REACTOME_UNFOLDED_PROTEIN_RESPONSE | View Gene Set | 9.151e-05 | 19 | 0.0004324 | 91 | Genes involved in Unfolded Protein Response | www.broad.mit.e... |
Broad REACTOME_UNWINDING_OF_DNA | View Gene Set | 9.619e-05 | 11 | 0.0004496 | 92 | Genes involved in Unwinding of DNA | www.broad.mit.e... |
Broad REACTOME_APCDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B | View Gene Set | 0.000113 | 18 | 0.0005125 | 93 | Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B | www.broad.mit.e... |
Broad REACTOME_INACTIVATION_OF_APC_VIA_DIRECT_INHIBITION_OF_THE_APCOMPLEX | View Gene Set | 0.0001114 | 18 | 0.0005125 | 93 | Genes involved in Inactivation of APC/C via direct inhibition of the APC/C complex | www.broad.mit.e... |
Broad REACTOME_MRNA_3_END_PROCESSING | View Gene Set | 0.0001132 | 25 | 0.0005125 | 93 | Genes involved in mRNA 3-end processing | www.broad.mit.e... |
Broad REACTOME_PHOSPHORYLATION_OF_THE_APC | View Gene Set | 0.000122 | 17 | 0.0005465 | 96 | Genes involved in Phosphorylation of the APC/C | www.broad.mit.e... |
Broad REACTOME_GLUCOSE_METABOLISM | View Gene Set | 0.0001355 | 56 | 0.0006007 | 97 | Genes involved in Glucose metabolism | www.broad.mit.e... |
Broad REACTOME_GLUCOSE_TRANSPORT | View Gene Set | 0.0001396 | 38 | 0.0006126 | 98 | Genes involved in Glucose transport | www.broad.mit.e... |
Broad REACTOME_PEROXISOMAL_LIPID_METABOLISM | View Gene Set | 0.0001483 | 20 | 0.0006442 | 99 | Genes involved in Peroxisomal lipid metabolism | www.broad.mit.e... |
Broad REACTOME_SIGNALLING_BY_NGF | View Gene Set | 0.0001709 | 216 | 0.000735 | 100 | Genes involved in Signalling by NGF | www.broad.mit.e... |
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION | View Gene Set | 0.0001837 | 34 | 0.0007822 | 101 | Genes involved in RNA Polymerase III Transcription | www.broad.mit.e... |
Broad REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | View Gene Set | 0.0001903 | 15 | 0.0007946 | 102 | Genes involved in Formation of ATP by chemiosmotic coupling | www.broad.mit.e... |
Broad REACTOME_ACTIVATION_OF_CHAPERONES_BY_IRE1_ALPHA | View Gene Set | 0.0001891 | 10 | 0.0007946 | 102 | Genes involved in Activation of Chaperones by IRE1alpha | www.broad.mit.e... |
Broad REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME | View Gene Set | 0.0002058 | 59 | 0.0008509 | 104 | Genes involved in Transcription of the HIV genome | www.broad.mit.e... |
Broad REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE | View Gene Set | 0.0002833 | 103 | 0.00116 | 105 | Genes involved in TRKA signalling from the plasma membrane | www.broad.mit.e... |
Broad REACTOME_MTORC1_MEDIATED_SIGNALLING | View Gene Set | 0.0003163 | 11 | 0.001283 | 106 | Genes involved in mTORC1-mediated signalling | www.broad.mit.e... |
Broad REACTOME_TRANSFORMATION_OF_LANOSTEROL_TO_CHOLESTEROL | View Gene Set | 0.0003256 | 10 | 0.001309 | 107 | Genes involved in Transformation of lanosterol to cholesterol | www.broad.mit.e... |
Broad REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | View Gene Set | 0.000403 | 11 | 0.001605 | 108 | Genes involved in Purine ribonucleoside monophosphate biosynthesis | www.broad.mit.e... |
Broad REACTOME_SIGNALING_BY_EGFR | View Gene Set | 0.0004168 | 48 | 0.001644 | 109 | Genes involved in Signaling by EGFR | www.broad.mit.e... |
Broad REACTOME_HIV1_TRANSCRIPTION_ELONGATION | View Gene Set | 0.0004608 | 41 | 0.001801 | 110 | Genes involved in HIV-1 Transcription Elongation | www.broad.mit.e... |
Broad REACTOME_G1_PHASE | View Gene Set | 0.0004748 | 16 | 0.001839 | 111 | Genes involved in G1 Phase | www.broad.mit.e... |
Broad REACTOME_LAGGING_STRAND_SYNTHESIS | View Gene Set | 0.0005461 | 20 | 0.002074 | 112 | Genes involved in Lagging Strand Synthesis | www.broad.mit.e... |
Broad REACTOME_P38MAPK_EVENTS | View Gene Set | 0.0005478 | 13 | 0.002074 | 112 | Genes involved in p38MAPK events | www.broad.mit.e... |
Broad REACTOME_RNA_POLYMERASE_I_III_AND_MITOCHONDRIAL_TRANSCRIPTION | View Gene Set | 0.0005498 | 120 | 0.002074 | 112 | Genes involved in RNA Polymerase I RNA Polymerase III and Mitochondrial Transcription | www.broad.mit.e... |
Broad REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | View Gene Set | 0.0005669 | 29 | 0.00212 | 115 | Genes involved in Association of TriC/CCT with target proteins during biosynthesis | www.broad.mit.e... |
Broad REACTOME_TRANSCRIPTION_COUPLED_NER | View Gene Set | 0.0008375 | 44 | 0.003105 | 116 | Genes involved in Transcription-coupled NER (TC-NER) | www.broad.mit.e... |
Broad REACTOME_FURTHER_PLATELET_RELEASATE | View Gene Set | 0.0008966 | 24 | 0.003295 | 117 | Genes involved in Further platelet releasate | www.broad.mit.e... |
Broad REACTOME_PI3K_AKT_SIGNALLING | View Gene Set | 0.0009998 | 37 | 0.003643 | 118 | Genes involved in PI3K/AKT signalling | www.broad.mit.e... |
Broad REACTOME_MICRORNA_BIOGENESIS | View Gene Set | 0.00103 | 18 | 0.003721 | 119 | Genes involved in MicroRNA biogenesis | www.broad.mit.e... |
Broad REACTOME_SIGNALLING_TO_RAS | View Gene Set | 0.001104 | 26 | 0.003956 | 120 | Genes involved in Signalling to RAS | www.broad.mit.e... |
Broad REACTOME_TELOMERE_MAINTENANCE | View Gene Set | 0.001288 | 77 | 0.004577 | 121 | Genes involved in Telomere Maintenance | www.broad.mit.e... |
Broad REACTOME_DOWN_STREAM_SIGNAL_TRANSDUCTION | View Gene Set | 0.001381 | 35 | 0.004868 | 122 | Genes involved in Down-stream signal transduction | www.broad.mit.e... |
Broad REACTOME_CENTROSOME_MATURATION | View Gene Set | 0.001402 | 72 | 0.0049 | 123 | Genes involved in Centrosome maturation | www.broad.mit.e... |
Broad REACTOME_SHC_MEDIATED_SIGNALLING | View Gene Set | 0.001476 | 12 | 0.005119 | 124 | Genes involved in SHC-mediated signalling | www.broad.mit.e... |
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_TERMINATION | View Gene Set | 0.00151 | 17 | 0.005193 | 125 | Genes involved in RNA Polymerase III Transcription Termination | www.broad.mit.e... |
Broad REACTOME_GRB2_EVENTS_IN_EGFR_SIGNALING | View Gene Set | 0.001551 | 13 | 0.005292 | 126 | Genes involved in Grb2 events in EGFR signaling | www.broad.mit.e... |
Broad REACTOME_IRS_RELATED_EVENTS | View Gene Set | 0.001594 | 79 | 0.005399 | 127 | Genes involved in IRS-related events | www.broad.mit.e... |
Broad REACTOME_POLYMERASE_SWITCHING | View Gene Set | 0.001713 | 14 | 0.005754 | 128 | Genes involved in Polymerase switching | www.broad.mit.e... |
Broad REACTOME_ERK_MAPK_TARGETS | View Gene Set | 0.001958 | 21 | 0.006525 | 129 | Genes involved in ERK/MAPK targets | www.broad.mit.e... |
Broad REACTOME_LYSOSOME_VESICLE_BIOGENESIS | View Gene Set | 0.002009 | 24 | 0.006594 | 130 | Genes involved in Lysosome Vesicle Biogenesis | www.broad.mit.e... |
Broad REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | View Gene Set | 0.002005 | 42 | 0.006594 | 130 | Genes involved in Metabolism of vitamins and cofactors | www.broad.mit.e... |
Broad REACTOME_DOUBLE_STRAND_BREAK_REPAIR | View Gene Set | 0.002168 | 21 | 0.007064 | 132 | Genes involved in Double-Strand Break Repair | www.broad.mit.e... |
Broad REACTOME_SHC_RELATED_EVENTS | View Gene Set | 0.002309 | 14 | 0.007467 | 133 | Genes involved in SHC-related events | www.broad.mit.e... |
Broad REACTOME_DUAL_INCISION_REACTION_IN_GG_NER | View Gene Set | 0.002346 | 20 | 0.007527 | 134 | Genes involved in Dual incision reaction in GG-NER | www.broad.mit.e... |
Broad REACTOME_SPHINGOLIPID_METABOLISM | View Gene Set | 0.002381 | 32 | 0.007583 | 135 | Genes involved in Sphingolipid metabolism | www.broad.mit.e... |
Broad REACTOME_REPAIR_SYNTHESIS_OF_PATCH_27_30_BASES_LONG_BY_DNA_POLYMERASE | View Gene Set | 0.002575 | 15 | 0.008083 | 136 | Genes involved in Repair synthesis of patch ~27-30 bases long by DNA polymerase | www.broad.mit.e... |
Broad REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | View Gene Set | 0.002561 | 11 | 0.008083 | 136 | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease | www.broad.mit.e... |
Broad REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | View Gene Set | 0.002602 | 17 | 0.008109 | 138 | Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK | www.broad.mit.e... |
Broad REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | View Gene Set | 0.002672 | 24 | 0.008265 | 139 | Genes involved in Nuclear Events (kinase and transcription factor activation) | www.broad.mit.e... |
Broad REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | View Gene Set | 0.002873 | 13 | 0.008825 | 140 | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease | www.broad.mit.e... |
Broad REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS | View Gene Set | 0.003146 | 228 | 0.009526 | 141 | Genes involved in Metabolism of lipids and lipoproteins | www.broad.mit.e... |
Broad REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PREREPLICATIVE_COMPLEX | View Gene Set | 0.003143 | 12 | 0.009526 | 141 | Genes involved in Association of licensing factors with the pre-replicative complex | www.broad.mit.e... |
Broad REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | View Gene Set | 0.00326 | 14 | 0.009803 | 143 | Genes involved in AKT phosphorylates targets in the cytosol | www.broad.mit.e... |
Broad REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING | View Gene Set | 0.003483 | 50 | 0.0104 | 144 | Genes involved in Chaperonin-mediated protein folding | www.broad.mit.e... |
Broad REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE | View Gene Set | 0.00372 | 14 | 0.01103 | 145 | Genes involved in Removal of the Flap Intermediate | www.broad.mit.e... |
Broad REACTOME_TAT_MEDIATED_HIV1_ELONGATION_ARREST_AND_RECOVERY | View Gene Set | 0.003808 | 30 | 0.01122 | 146 | Genes involved in Tat-mediated HIV-1 elongation arrest and recovery | www.broad.mit.e... |
Broad REACTOME_CONVERSION_FROM_APC_CDC20_TO_APC_CDH1_IN_LATE_ANAPHASE | View Gene Set | 0.004016 | 17 | 0.01172 | 147 | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | www.broad.mit.e... |
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION | View Gene Set | 0.004034 | 29 | 0.01172 | 147 | Genes involved in RNA Polymerase III Transcription Initiation | www.broad.mit.e... |
Broad REACTOME_FORMATION_OF_THE_EARLY_ELONGATION_COMPLEX | View Gene Set | 0.004309 | 32 | 0.01243 | 149 | Genes involved in Formation of the Early Elongation Complex | www.broad.mit.e... |
Broad REACTOME_COPI_MEDIATED_TRANSPORT | View Gene Set | 0.004339 | 10 | 0.01244 | 150 | Genes involved in COPI Mediated Transport | www.broad.mit.e... |
Broad REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC:ORIGIN_COMPLEX | View Gene Set | 0.004797 | 11 | 0.01366 | 151 | Genes involved in CDC6 association with the ORC:origin complex | www.broad.mit.e... |
Broad REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | View Gene Set | 0.004891 | 62 | 0.01375 | 152 | Genes involved in Loss of Nlp from mitotic centrosomes | www.broad.mit.e... |
Broad REACTOME_VITAMIN_B5_(PANTOTHENATE)_METABOLISM | View Gene Set | 0.004894 | 11 | 0.01375 | 152 | Genes involved in Vitamin B5 (pantothenate) metabolism | www.broad.mit.e... |
Broad REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL | View Gene Set | 0.00493 | 17 | 0.01376 | 154 | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) | www.broad.mit.e... |
Broad REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | View Gene Set | 0.005373 | 17 | 0.01488 | 155 | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle | www.broad.mit.e... |
Broad REACTOME_PURINE_SALVAGE_REACTIONS | View Gene Set | 0.005425 | 12 | 0.01488 | 155 | Genes involved in Purine salvage reactions | www.broad.mit.e... |
Broad REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | View Gene Set | 0.005432 | 22 | 0.01488 | 155 | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter | www.broad.mit.e... |
Broad REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | View Gene Set | 0.005544 | 10 | 0.01509 | 158 | Genes involved in Removal of the Flap Intermediate from the C-strand | www.broad.mit.e... |
Broad REACTOME_SIGNALLING_TO_ERKS | View Gene Set | 0.006256 | 34 | 0.01692 | 159 | Genes involved in Signalling to ERKs | www.broad.mit.e... |
Broad REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION | View Gene Set | 0.006425 | 24 | 0.01727 | 160 | Genes involved in RNA PolymeraseTranscription Initiation | www.broad.mit.e... |
Broad REACTOME_CHOLESTEROL_BIOSYNTHESIS | View Gene Set | 0.007146 | 21 | 0.01895 | 161 | Genes involved in Cholesterol biosynthesis | www.broad.mit.e... |
Broad REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | View Gene Set | 0.007158 | 10 | 0.01895 | 161 | Genes involved in E2F-enabled inhibition of pre-replication complex formation | www.broad.mit.e... |
Broad REACTOME_HIV1_TRANSCRIPTION_INITIATION | View Gene Set | 0.007185 | 39 | 0.01895 | 161 | Genes involved in HIV-1 Transcription Initiation | www.broad.mit.e... |
Broad REACTOME_PYRIMIDINE_METABOLISM | View Gene Set | 0.007403 | 22 | 0.01941 | 164 | Genes involved in Pyrimidine metabolism | www.broad.mit.e... |
Broad REACTOME_ZINC_INFLUX_INTO_CELLS_BY_THE_SLC39_GENES_FAMILY | View Gene Set | 0.008231 | 10 | 0.02145 | 165 | Genes involved in Zinc influx into cells by the SLC39 Genes family | www.broad.mit.e... |
Broad REACTOME_MRNA_PROCESSING | View Gene Set | 0.009177 | 32 | 0.02377 | 166 | Genes involved in mRNA Processing | www.broad.mit.e... |
Broad REACTOME_GLUCONEOGENESIS | View Gene Set | 0.009973 | 31 | 0.02568 | 167 | Genes involved in Gluconeogenesis | www.broad.mit.e... |
Broad REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 | View Gene Set | 0.01085 | 14 | 0.02778 | 168 | Genes involved in Regulation of AMPK activity via LKB1 | www.broad.mit.e... |
Broad REACTOME_RNA_POL_II_CTD_PHOSPHORYLATION_AND_INTERACTION_WITH_CE | View Gene Set | 0.01235 | 26 | 0.03141 | 169 | Genes involved in RNA Pol II CTD phosphorylation and interaction with CE | www.broad.mit.e... |
Broad REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | View Gene Set | 0.01265 | 11 | 0.03199 | 170 | Genes involved in Recruitment of NuMA to mitotic centrosomes | www.broad.mit.e... |
Broad REACTOME_BASE_EXCISION_REPAIR | View Gene Set | 0.01295 | 18 | 0.03238 | 171 | Genes involved in Base Excision Repair | www.broad.mit.e... |
Broad REACTOME_SMOOTH_MUSCLE_CONTRACTION | View Gene Set | 0.01295 | 24 | 0.03238 | 171 | Genes involved in Smooth Muscle Contraction | www.broad.mit.e... |
Broad REACTOME_GLYCOLYSIS | View Gene Set | 0.01434 | 22 | 0.03564 | 173 | Genes involved in Glycolysis | www.broad.mit.e... |
Broad REACTOME_REMOVAL_OF_DNA_PATCH_CONTAINING_ABASIC_RESIDUE | View Gene Set | 0.01492 | 15 | 0.03687 | 174 | Genes involved in Removal of DNA patch containing abasic residue | www.broad.mit.e... |
Broad REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | View Gene Set | 0.01529 | 10 | 0.03758 | 175 | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation | www.broad.mit.e... |
Broad REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | View Gene Set | 0.01627 | 11 | 0.03976 | 176 | Genes involved in Apoptotic cleavage of cell adhesion proteins | www.broad.mit.e... |
Broad REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | View Gene Set | 0.01654 | 28 | 0.04018 | 177 | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC | www.broad.mit.e... |
Broad REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | View Gene Set | 0.01824 | 20 | 0.04407 | 178 | Genes involved in Mitochondrial tRNA aminoacylation | www.broad.mit.e... |
Broad REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT | View Gene Set | 0.01956 | 23 | 0.047 | 179 | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat | www.broad.mit.e... |
Broad REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE | View Gene Set | 0.0199 | 20 | 0.04754 | 180 | Genes involved in RNA Polymerase I Promoter Escape | www.broad.mit.e... |
Broad REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR | View Gene Set | 0.02084 | 15 | 0.04945 | 181 | Genes involved in Homologous Recombination Repair | www.broad.mit.e... |
Broad REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | View Gene Set | 0.02093 | 10 | 0.04945 | 181 | Genes involved in Regulation of Rheb GTPase activity by AMPK | www.broad.mit.e... |
Broad REACTOME_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | View Gene Set | 0.02106 | 26 | 0.04948 | 183 | Genes involved in Synthesis of GPI-anchored proteins | www.broad.mit.e... |
Broad REACTOME_BETACATENIN_PHOSPHORYLATION_CASCADE | View Gene Set | 0.02127 | 13 | 0.04971 | 184 | Genes involved in Beta-catenin phosphorylation cascade | www.broad.mit.e... |
Broad REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE | View Gene Set | 0.02142 | 13 | 0.04979 | 185 | Genes involved in Early Phase of HIV Life Cycle | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad GTGCCTT MIR-506 | View Gene Set | 1.144e-07 | 605 | 9.527e-06 | 1 | Targets of MicroRNA GTGCCTT MIR-506 | www.broad.mit.e... MIR-506... |
Broad CTTGTAT MIR-381 | View Gene Set | 1.733e-07 | 167 | 9.527e-06 | 1 | Targets of MicroRNA CTTGTAT MIR-381 | www.broad.mit.e... MIR-381... |
Broad TGCCTTA MIR-124A | View Gene Set | 1.307e-07 | 471 | 9.527e-06 | 1 | Targets of MicroRNA TGCCTTA MIR-124A | www.broad.mit.e... MIR-124A... |
Broad TTTTGAG MIR-373 | View Gene Set | 5.576e-08 | 189 | 9.527e-06 | 1 | Targets of MicroRNA TTTTGAG MIR-373 | www.broad.mit.e... MIR-373... |
Broad TAATGTG MIR-323 | View Gene Set | 2.155e-07 | 135 | 9.527e-06 | 1 | Targets of MicroRNA TAATGTG MIR-323 | www.broad.mit.e... MIR-323... |
Broad ATGAAGG MIR-205 | View Gene Set | 5.07e-07 | 128 | 1.867e-05 | 6 | Targets of MicroRNA ATGAAGG MIR-205 | www.broad.mit.e... MIR-205... |
Broad ACCATTT MIR-522 | View Gene Set | 8.337e-07 | 137 | 2.632e-05 | 7 | Targets of MicroRNA ACCATTT MIR-522 | www.broad.mit.e... MIR-522... |
Broad ACATTCC MIR-1 MIR-206 | View Gene Set | 3.772e-06 | 248 | 0.0001042 | 8 | Targets of MicroRNA ACATTCC MIR-1 MIR-206 | www.broad.mit.e... MIR-1... MIR-206... |
Broad ATGTTAA MIR-302C | View Gene Set | 7.105e-06 | 206 | 0.0001745 | 9 | Targets of MicroRNA ATGTTAA MIR-302C | www.broad.mit.e... MIR-302C... |
Broad GGGACCA MIR-133A MIR-133B | View Gene Set | 8.821e-06 | 173 | 0.0001846 | 10 | Targets of MicroRNA GGGACCA MIR-133A MIR-133B | www.broad.mit.e... MIR-133A... MIR-133B... |
Broad ACACTAC MIR-142-3P | View Gene Set | 9.188e-06 | 110 | 0.0001846 | 10 | Targets of MicroRNA ACACTAC MIR-142-3P | www.broad.mit.e... MIR-142-3P... |
Broad CAGCTTT MIR-320 | View Gene Set | 2.521e-05 | 220 | 0.0004643 | 12 | Targets of MicroRNA CAGCTTT MIR-320 | www.broad.mit.e... MIR-320... |
Broad CAGTGTT MIR-141 MIR-200A | View Gene Set | 2.895e-05 | 262 | 0.0004922 | 13 | Targets of MicroRNA CAGTGTT MIR-141 MIR-200A | www.broad.mit.e... MIR-141... MIR-200A... |
Broad TGCTGCT MIR-15A MIR-16 MIR-15B MIR-195 MIR-424 MIR-497 | View Gene Set | 4.061e-05 | 512 | 0.000528 | 14 | Targets of MicroRNA TGCTGCT MIR-15A MIR-16 MIR-15B MIR-195 MIR-424 MIR-497 | www.broad.mit.e... MIR-15A... MIR-16... MIR-15B... MIR-195... MIR-424... MIR-497... |
Broad TGCACTT MIR-519C MIR-519B MIR-519A | View Gene Set | 3.846e-05 | 377 | 0.000528 | 14 | Targets of MicroRNA TGCACTT MIR-519C MIR-519B MIR-519A | www.broad.mit.e... MIR-519C... MIR-519B... MIR-519A... |
Broad TTGGAGA MIR-515-5P MIR-519E | View Gene Set | 3.923e-05 | 120 | 0.000528 | 14 | Targets of MicroRNA TTGGAGA MIR-515-5P MIR-519E | www.broad.mit.e... MIR-515-5P... MIR-519E... |
Broad TTGCCAA MIR-182 | View Gene Set | 4.02e-05 | 274 | 0.000528 | 14 | Targets of MicroRNA TTGCCAA MIR-182 | www.broad.mit.e... MIR-182... |
Broad GACTGTT MIR-212 MIR-132 | View Gene Set | 4.894e-05 | 134 | 0.0006009 | 18 | Targets of MicroRNA GACTGTT MIR-212 MIR-132 | www.broad.mit.e... MIR-212... MIR-132... |
Broad TTTGCAG MIR-518A-2 | View Gene Set | 9.928e-05 | 174 | 0.001155 | 19 | Targets of MicroRNA TTTGCAG MIR-518A-2 | www.broad.mit.e... MIR-518A-2... |
Broad AGTCAGC MIR-345 | View Gene Set | 0.0001577 | 52 | 0.00167 | 20 | Targets of MicroRNA AGTCAGC MIR-345 | www.broad.mit.e... MIR-345... |
Broad TATCTGG MIR-488 | View Gene Set | 0.0001587 | 49 | 0.00167 | 20 | Targets of MicroRNA TATCTGG MIR-488 | www.broad.mit.e... MIR-488... |
Broad ATATGCA MIR-448 | View Gene Set | 0.0002131 | 184 | 0.002141 | 22 | Targets of MicroRNA ATATGCA MIR-448 | www.broad.mit.e... MIR-448... |
Broad GAGACTG MIR-452 | View Gene Set | 0.0002465 | 78 | 0.002344 | 23 | Targets of MicroRNA GAGACTG MIR-452 | www.broad.mit.e... MIR-452... |
Broad TCCAGAG MIR-518C | View Gene Set | 0.0002545 | 127 | 0.002344 | 23 | Targets of MicroRNA TCCAGAG MIR-518C | www.broad.mit.e... MIR-518C... |
Broad GTACTGT MIR-101 | View Gene Set | 0.0002724 | 221 | 0.002408 | 25 | Targets of MicroRNA GTACTGT MIR-101 | www.broad.mit.e... MIR-101... |
Broad ACTGCAG MIR-17-3P | View Gene Set | 0.000294 | 88 | 0.002499 | 26 | Targets of MicroRNA ACTGCAG MIR-17-3P | www.broad.mit.e... MIR-17-3P... |
Broad GTGCAAT MIR-25 MIR-32 MIR-92 MIR-363 MIR-367 | View Gene Set | 0.0003181 | 260 | 0.002604 | 27 | Targets of MicroRNA GTGCAAT MIR-25 MIR-32 MIR-92 MIR-363 MIR-367 | www.broad.mit.e... MIR-25... MIR-32... MIR-92... MIR-363... MIR-367... |
Broad TGAGATT MIR-216 | View Gene Set | 0.0003416 | 90 | 0.002696 | 28 | Targets of MicroRNA TGAGATT MIR-216 | www.broad.mit.e... MIR-216... |
Broad TCATCTC MIR-143 | View Gene Set | 0.0003563 | 126 | 0.002715 | 29 | Targets of MicroRNA TCATCTC MIR-143 | www.broad.mit.e... MIR-143... |
Broad TCTGATA MIR-361 | View Gene Set | 0.0003902 | 74 | 0.002874 | 30 | Targets of MicroRNA TCTGATA MIR-361 | www.broad.mit.e... MIR-361... |
Broad AAAGGGA MIR-204 MIR-211 | View Gene Set | 0.0004463 | 191 | 0.003077 | 31 | Targets of MicroRNA AAAGGGA MIR-204 MIR-211 | www.broad.mit.e... MIR-204... MIR-211... |
Broad CTTTGTA MIR-524 | View Gene Set | 0.0004595 | 375 | 0.003077 | 31 | Targets of MicroRNA CTTTGTA MIR-524 | www.broad.mit.e... MIR-524... |
Broad ACTGCCT MIR-34B | View Gene Set | 0.0004477 | 190 | 0.003077 | 31 | Targets of MicroRNA ACTGCCT MIR-34B | www.broad.mit.e... MIR-34B... |
Broad TGTGTGA MIR-377 | View Gene Set | 0.0004896 | 162 | 0.003183 | 34 | Targets of MicroRNA TGTGTGA MIR-377 | www.broad.mit.e... MIR-377... |
Broad TACTTGA MIR-26A MIR-26B | View Gene Set | 0.0005146 | 258 | 0.003249 | 35 | Targets of MicroRNA TACTTGA MIR-26A MIR-26B | www.broad.mit.e... MIR-26A... MIR-26B... |
Broad ATAACCT MIR-154 | View Gene Set | 0.0006361 | 51 | 0.003905 | 36 | Targets of MicroRNA ATAACCT MIR-154 | www.broad.mit.e... MIR-154... |
Broad TTGGGAG MIR-150 | View Gene Set | 0.0006872 | 65 | 0.004105 | 37 | Targets of MicroRNA TTGGGAG MIR-150 | www.broad.mit.e... MIR-150... |
Broad GCACCTT MIR-18A MIR-18B | View Gene Set | 0.0007216 | 90 | 0.004197 | 38 | Targets of MicroRNA GCACCTT MIR-18A MIR-18B | www.broad.mit.e... MIR-18A... MIR-18B... |
Broad ATCATGA MIR-433 | View Gene Set | 0.0008131 | 94 | 0.004607 | 39 | Targets of MicroRNA ATCATGA MIR-433 | www.broad.mit.e... MIR-433... |
Broad ACACTGG MIR-199A MIR-199B | View Gene Set | 0.0008703 | 134 | 0.004809 | 40 | Targets of MicroRNA ACACTGG MIR-199A MIR-199B | www.broad.mit.e... MIR-199A... MIR-199B... |
Broad CAGTATT MIR-200B MIR-200C MIR-429 | View Gene Set | 0.0008968 | 386 | 0.004834 | 41 | Targets of MicroRNA CAGTATT MIR-200B MIR-200C MIR-429 | www.broad.mit.e... MIR-200B... MIR-200C... MIR-429... |
Broad ACACTCC MIR-122A | View Gene Set | 0.0009584 | 67 | 0.005043 | 42 | Targets of MicroRNA ACACTCC MIR-122A | www.broad.mit.e... MIR-122A... |
Broad AAGTCCA MIR-422B MIR-422A | View Gene Set | 0.001226 | 54 | 0.006299 | 43 | Targets of MicroRNA AAGTCCA MIR-422B MIR-422A | www.broad.mit.e... MIR-422B... MIR-422A... |
Broad TCTATGA MIR-376A MIR-376B | View Gene Set | 0.001699 | 71 | 0.008418 | 44 | Targets of MicroRNA TCTATGA MIR-376A MIR-376B | www.broad.mit.e... MIR-376A... MIR-376B... |
Broad CTGTTAC MIR-194 | View Gene Set | 0.001714 | 90 | 0.008418 | 44 | Targets of MicroRNA CTGTTAC MIR-194 | www.broad.mit.e... MIR-194... |
Broad GTGCCAT MIR-183 | View Gene Set | 0.002367 | 152 | 0.01137 | 46 | Targets of MicroRNA GTGCCAT MIR-183 | www.broad.mit.e... MIR-183... |
Broad ATTACAT MIR-380-3P | View Gene Set | 0.002497 | 87 | 0.01174 | 47 | Targets of MicroRNA ATTACAT MIR-380-3P | www.broad.mit.e... MIR-380-3P... |
Broad CATTTCA MIR-203 | View Gene Set | 0.002565 | 235 | 0.01181 | 48 | Targets of MicroRNA CATTTCA MIR-203 | www.broad.mit.e... MIR-203... |
Broad CACTGTG MIR-128A MIR-128B | View Gene Set | 0.002752 | 276 | 0.01228 | 49 | Targets of MicroRNA CACTGTG MIR-128A MIR-128B | www.broad.mit.e... MIR-128A... MIR-128B... |
Broad GGCAGTG MIR-324-3P | View Gene Set | 0.002818 | 82 | 0.01228 | 49 | Targets of MicroRNA GGCAGTG MIR-324-3P | www.broad.mit.e... MIR-324-3P... |
Broad TTTGTAG MIR-520D | View Gene Set | 0.002945 | 279 | 0.01228 | 49 | Targets of MicroRNA TTTGTAG MIR-520D | www.broad.mit.e... MIR-520D... |
Broad AACTGGA MIR-145 | View Gene Set | 0.002925 | 191 | 0.01228 | 49 | Targets of MicroRNA AACTGGA MIR-145 | www.broad.mit.e... MIR-145... |
Broad CACCAGC MIR-138 | View Gene Set | 0.002849 | 173 | 0.01228 | 49 | Targets of MicroRNA CACCAGC MIR-138 | www.broad.mit.e... MIR-138... |
Broad ACAACTT MIR-382 | View Gene Set | 0.003604 | 64 | 0.01448 | 54 | Targets of MicroRNA ACAACTT MIR-382 | www.broad.mit.e... MIR-382... |
Broad GTCTTCC MIR-7 | View Gene Set | 0.003583 | 132 | 0.01448 | 54 | Targets of MicroRNA GTCTTCC MIR-7 | www.broad.mit.e... MIR-7... |
Broad CTCTGGA MIR-520A MIR-525 | View Gene Set | 0.003726 | 128 | 0.0147 | 56 | Targets of MicroRNA CTCTGGA MIR-520A MIR-525 | www.broad.mit.e... MIR-520A... MIR-525... |
Broad CAGTCAC MIR-134 | View Gene Set | 0.004364 | 38 | 0.01692 | 57 | Targets of MicroRNA CAGTCAC MIR-134 | www.broad.mit.e... MIR-134... |
Broad TAGGTCA MIR-192 MIR-215 | View Gene Set | 0.004469 | 37 | 0.01703 | 58 | Targets of MicroRNA TAGGTCA MIR-192 MIR-215 | www.broad.mit.e... MIR-192... MIR-215... |
Broad ATTCTTT MIR-186 | View Gene Set | 0.004851 | 232 | 0.01817 | 59 | Targets of MicroRNA ATTCTTT MIR-186 | www.broad.mit.e... MIR-186... |
Broad GTTTGTT MIR-495 | View Gene Set | 0.005372 | 205 | 0.01979 | 60 | Targets of MicroRNA GTTTGTT MIR-495 | www.broad.mit.e... MIR-495... |
Broad TGAATGT MIR-181A MIR-181B MIR-181C MIR-181D | View Gene Set | 0.006209 | 418 | 0.02226 | 61 | Targets of MicroRNA TGAATGT MIR-181A MIR-181B MIR-181C MIR-181D | www.broad.mit.e... MIR-181A... MIR-181B... MIR-181C... MIR-181D... |
Broad AAAGGAT MIR-501 | View Gene Set | 0.006244 | 107 | 0.02226 | 61 | Targets of MicroRNA AAAGGAT MIR-501 | www.broad.mit.e... MIR-501... |
Broad ACTTTAT MIR-142-5P | View Gene Set | 0.006465 | 250 | 0.02268 | 63 | Targets of MicroRNA ACTTTAT MIR-142-5P | www.broad.mit.e... MIR-142-5P... |
Broad CATGTAA MIR-496 | View Gene Set | 0.006677 | 150 | 0.02306 | 64 | Targets of MicroRNA CATGTAA MIR-496 | www.broad.mit.e... MIR-496... |
Broad AAGCACT MIR-520F | View Gene Set | 0.007041 | 198 | 0.02394 | 65 | Targets of MicroRNA AAGCACT MIR-520F | www.broad.mit.e... MIR-520F... |
Broad ACTGTAG MIR-139 | View Gene Set | 0.007353 | 111 | 0.02462 | 66 | Targets of MicroRNA ACTGTAG MIR-139 | www.broad.mit.e... MIR-139... |
Broad TTTGCAC MIR-19A MIR-19B | View Gene Set | 0.008535 | 440 | 0.02774 | 67 | Targets of MicroRNA TTTGCAC MIR-19A MIR-19B | www.broad.mit.e... MIR-19A... MIR-19B... |
Broad GAGCCAG MIR-149 | View Gene Set | 0.008466 | 125 | 0.02774 | 67 | Targets of MicroRNA GAGCCAG MIR-149 | www.broad.mit.e... MIR-149... |
Broad ATGCAGT MIR-217 | View Gene Set | 0.008792 | 93 | 0.02816 | 69 | Targets of MicroRNA ATGCAGT MIR-217 | www.broad.mit.e... MIR-217... |
Broad GTATGAT MIR-154 MIR-487 | View Gene Set | 0.009098 | 51 | 0.02873 | 70 | Targets of MicroRNA GTATGAT MIR-154 MIR-487 | www.broad.mit.e... MIR-154... MIR-487... |
Broad CAGCAGG MIR-370 | View Gene Set | 0.01004 | 128 | 0.03125 | 71 | Targets of MicroRNA CAGCAGG MIR-370 | www.broad.mit.e... MIR-370... |
Broad TCCGTCC MIR-184 | View Gene Set | 0.01021 | 10 | 0.03135 | 72 | Targets of MicroRNA TCCGTCC MIR-184 | www.broad.mit.e... MIR-184... |
Broad TTGCACT MIR-130A MIR-301 MIR-130B | View Gene Set | 0.01041 | 335 | 0.03151 | 73 | Targets of MicroRNA TTGCACT MIR-130A MIR-301 MIR-130B | www.broad.mit.e... MIR-130A... MIR-301... MIR-130B... |
Broad GTAAACC MIR-299-5P | View Gene Set | 0.011 | 44 | 0.03284 | 74 | Targets of MicroRNA GTAAACC MIR-299-5P | www.broad.mit.e... MIR-299-5P... |
Broad GCTCTTG MIR-335 | View Gene Set | 0.01155 | 70 | 0.03322 | 75 | Targets of MicroRNA GCTCTTG MIR-335 | www.broad.mit.e... MIR-335... |
Broad TAGCTTT MIR-9 | View Gene Set | 0.01131 | 198 | 0.03322 | 75 | Targets of MicroRNA TAGCTTT MIR-9 | www.broad.mit.e... MIR-9... |
Broad TCTGGAC MIR-198 | View Gene Set | 0.01157 | 69 | 0.03322 | 75 | Targets of MicroRNA TCTGGAC MIR-198 | www.broad.mit.e... MIR-198... |
Broad TCCAGAT MIR-516-5P | View Gene Set | 0.0118 | 93 | 0.03344 | 78 | Targets of MicroRNA TCCAGAT MIR-516-5P | www.broad.mit.e... MIR-516-5P... |
Broad GCTGAGT MIR-512-5P | View Gene Set | 0.01249 | 48 | 0.03494 | 79 | Targets of MicroRNA GCTGAGT MIR-512-5P | www.broad.mit.e... MIR-512-5P... |
Broad AGCACTT MIR-93 MIR-302A MIR-302B MIR-302C MIR-302D MIR-372 MIR-373 MIR-520E MIR-520A MIR-526B MIR-520B MIR-520C MIR-520D | View Gene Set | 0.0132 | 281 | 0.03646 | 80 | Targets of MicroRNA AGCACTT MIR-93 MIR-302A MIR-302B MIR-302C MIR-302D MIR-372 MIR-373 MIR-520E MIR-520A MIR-526B MIR-520B MIR-520C MIR-520D | www.broad.mit.e... MIR-93... MIR-302A... MIR-302B... MIR-302C... MIR-302D... MIR-372... MIR-373... MIR-520E... MIR-520A... MIR-526B... MIR-520B... MIR-520C... MIR-520D... |
Broad AAGGGAT MIR-188 | View Gene Set | 0.01356 | 65 | 0.03701 | 81 | Targets of MicroRNA AAGGGAT MIR-188 | www.broad.mit.e... MIR-188... |
Broad AGGTGCA MIR-500 | View Gene Set | 0.01393 | 79 | 0.03755 | 82 | Targets of MicroRNA AGGTGCA MIR-500 | www.broad.mit.e... MIR-500... |
Broad AGGCACT MIR-515-3P | View Gene Set | 0.01457 | 74 | 0.03878 | 83 | Targets of MicroRNA AGGCACT MIR-515-3P | www.broad.mit.e... MIR-515-3P... |
Broad GCACTTT MIR-17-5P MIR-20A MIR-106A MIR-106B MIR-20B MIR-519D | View Gene Set | 0.01505 | 506 | 0.03958 | 84 | Targets of MicroRNA GCACTTT MIR-17-5P MIR-20A MIR-106A MIR-106B MIR-20B MIR-519D | www.broad.mit.e... MIR-17-5P... MIR-20A... MIR-106A... MIR-106B... MIR-20B... MIR-519D... |
Broad CTCCAAG MIR-432 | View Gene Set | 0.01552 | 65 | 0.04036 | 85 | Targets of MicroRNA CTCCAAG MIR-432 | www.broad.mit.e... MIR-432... |
Broad CTCAGGG MIR-125B MIR-125A | View Gene Set | 0.01591 | 277 | 0.04059 | 86 | Targets of MicroRNA CTCAGGG MIR-125B MIR-125A | www.broad.mit.e... MIR-125B... MIR-125A... |
Broad ATGTACA MIR-493 | View Gene Set | 0.01598 | 261 | 0.04059 | 86 | Targets of MicroRNA ATGTACA MIR-493 | www.broad.mit.e... MIR-493... |
Broad CCAGGTT MIR-490 | View Gene Set | 0.01853 | 52 | 0.04602 | 88 | Targets of MicroRNA CCAGGTT MIR-490 | www.broad.mit.e... MIR-490... |
Broad GCATTTG MIR-105 | View Gene Set | 0.01853 | 143 | 0.04602 | 88 | Targets of MicroRNA GCATTTG MIR-105 | www.broad.mit.e... MIR-105... |
Broad ATACTGT MIR-144 | View Gene Set | 0.0203 | 173 | 0.04985 | 90 | Targets of MicroRNA ATACTGT MIR-144 | www.broad.mit.e... MIR-144... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad SCGGAAGY_V$ELK1_02 | View Gene Set | 5.178e-40 | 784 | 3.184e-37 | 1 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SCGGAAGY which matches annotation for ELK1: ELK1 member of ETS oncogene family | www.broad.mit.e... |
Broad RCGCANGCGY_V$NRF1_Q6 | View Gene Set | 1.944e-32 | 580 | 5.978e-30 | 2 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif RCGCANGCGY which matches annotation for NRF1: nuclear respiratory factor 1 | www.broad.mit.e... |
Broad GCCATNTTG_V$YY1_Q6 | View Gene Set | 3.66e-25 | 289 | 7.502e-23 | 3 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTG which matches annotation for YY1: YY1 transcription factor | www.broad.mit.e... |
Broad GGGCGGR_V$SP1_Q6 | View Gene Set | 1.024e-22 | 2120 | 1.574e-20 | 4 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGGCGGR which matches annotation for SP1: Sp1 transcription factor | www.broad.mit.e... |
Broad CACGTG_V$MYC_Q2 | View Gene Set | 1.308e-19 | 734 | 1.608e-17 | 5 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CACGTG which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian) | www.broad.mit.e... |
Broad V$NFMUE1_Q6 | View Gene Set | 5.455e-18 | 175 | 5.591e-16 | 6 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CGGCCATCT. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad MGGAAGTG_V$GABP_B | View Gene Set | 3.899e-17 | 512 | 3.425e-15 | 7 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif MGGAAGTG which matches annotation for GABPA: GA binding protein transcription factor alpha subunit 60kDa<br> GABPB2: GA binding protein transcription factor beta subunit 2 | www.broad.mit.e... |
Broad V$YY1_Q6 | View Gene Set | 6.546e-17 | 166 | 5.033e-15 | 8 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCATNTTN which matches annotation for YY1: YY1 transcription factor | www.broad.mit.e... |
Broad V$GABP_B | View Gene Set | 1.398e-14 | 162 | 9.555e-13 | 9 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif VCCGGAAGNGCR which matches annotation for GABPA: GA binding protein transcription factor alpha subunit 60kDa<br> GABPB2: GA binding protein transcription factor beta subunit 2 | www.broad.mit.e... |
Broad V$ELK1_02 | View Gene Set | 1.003e-12 | 170 | 6.169e-11 | 10 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNCCGGAARTNN which matches annotation for ELK1: ELK1 member of ETS oncogene family | www.broad.mit.e... |
Broad GGCNKCCATNK_UNKNOWN | View Gene Set | 2.167e-12 | 84 | 1.162e-10 | 11 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGCNKCCATNK. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad TGCGCANK_UNKNOWN | View Gene Set | 2.268e-12 | 361 | 1.162e-10 | 11 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TGCGCANK. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad TMTCGCGANR_UNKNOWN | View Gene Set | 4.946e-12 | 100 | 2.34e-10 | 13 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TMTCGCGANR. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$YY1_02 | View Gene Set | 1.709e-11 | 168 | 7.509e-10 | 14 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNCGGCCATCTTGNCTSNW which matches annotation for YY1: YY1 transcription factor | www.broad.mit.e... |
Broad V$NRF2_01 | View Gene Set | 7.105e-11 | 166 | 2.736e-09 | 15 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif ACCGGAAGNG which matches annotation for GABPB1: GA binding protein transcription factor beta subunit 1. | www.broad.mit.e... |
Broad ACTAYRNNNCCCR_UNKNOWN | View Gene Set | 7.119e-11 | 293 | 2.736e-09 | 15 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ACTAYRNNNCCCR. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F1_Q6_01 | View Gene Set | 2.25e-10 | 177 | 8.141e-09 | 17 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTTCGCGCS which matches annotation for E2F1: E2F transcription factor 1 | www.broad.mit.e... |
Broad GGCNNMSMYNTTG_UNKNOWN | View Gene Set | 3.741e-10 | 56 | 1.278e-08 | 18 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGCNNMSMYNTTG. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad SGCGSSAAA_V$E2F1DP2_01 | View Gene Set | 8.251e-10 | 122 | 2.671e-08 | 19 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SGCGSSAAA which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) | www.broad.mit.e... |
Broad V$E2F_03 | View Gene Set | 1.116e-09 | 171 | 3.432e-08 | 20 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGCGMNR. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$ARNT_02 | View Gene Set | 1.28e-09 | 179 | 3.749e-08 | 21 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNRTCACGTGAYNNNNN which matches annotation for ARNT: aryl hydrocarbon receptor nuclear translocator | www.broad.mit.e... |
Broad KCCGNSWTTT_UNKNOWN | View Gene Set | 3.075e-09 | 76 | 8.595e-08 | 22 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KCCGNSWTTT. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$SREBP1_01 | View Gene Set | 4.241e-09 | 133 | 1.134e-07 | 23 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NATCACGTGAY which matches annotation for SREBF1: sterol regulatory element binding transcription factor 1 | www.broad.mit.e... |
Broad TCCCRNNRTGC_UNKNOWN | View Gene Set | 6.524e-09 | 130 | 1.672e-07 | 24 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TCCCRNNRTGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F1_Q6 | View Gene Set | 8.634e-09 | 167 | 2.124e-07 | 25 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGS which matches annotation for E2F1: E2F transcription factor 1 | www.broad.mit.e... |
Broad V$MYCMAX_01 | View Gene Set | 9.061e-09 | 189 | 2.143e-07 | 26 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNACCACGTGGTNN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X | www.broad.mit.e... |
Broad V$E2F1_Q4_01 | View Gene Set | 1.029e-08 | 167 | 2.345e-07 | 27 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad GATTGGY_V$NFY_Q6_01 | View Gene Set | 1.195e-08 | 830 | 2.624e-07 | 28 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GATTGGY. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F_Q6 | View Gene Set | 1.319e-08 | 165 | 2.798e-07 | 29 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F_Q3_01 | View Gene Set | 1.664e-08 | 171 | 3.411e-07 | 30 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGSG which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad V$E2F_Q4 | View Gene Set | 1.791e-08 | 166 | 3.554e-07 | 31 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGS. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$CETS1P54_01 | View Gene Set | 2.953e-08 | 183 | 5.675e-07 | 32 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCMGGAWGYN which matches annotation for ETS1: v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | www.broad.mit.e... |
Broad V$USF_01 | View Gene Set | 3.755e-08 | 186 | 6.997e-07 | 33 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNRYCACGTGRYNN. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad GTGACGY_V$E4F1_Q6 | View Gene Set | 8.532e-08 | 462 | 1.499e-06 | 34 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GTGACGY which matches annotation for E4F1: E4F transcription factor 1 | www.broad.mit.e... |
Broad TCANNTGAY_V$SREBP1_01 | View Gene Set | 8.289e-08 | 355 | 1.499e-06 | 34 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TCANNTGAY which matches annotation for SREBF1: sterol regulatory element binding transcription factor 1 | www.broad.mit.e... |
Broad V$NRF1_Q6 | View Gene Set | 1.39e-07 | 151 | 2.374e-06 | 36 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CGCATGCGCR which matches annotation for NRF1: nuclear respiratory factor 1 | www.broad.mit.e... |
Broad V$E2F_Q3 | View Gene Set | 2.412e-07 | 162 | 4.009e-06 | 37 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTCGCGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad TAANNYSGCG_UNKNOWN | View Gene Set | 2.949e-07 | 60 | 4.773e-06 | 38 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TAANNYSGCG. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F_Q6_01 | View Gene Set | 3.19e-07 | 167 | 5.031e-06 | 39 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKCGCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad ACAWNRNSRCGG_UNKNOWN | View Gene Set | 3.788e-07 | 50 | 5.824e-06 | 40 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ACAWNRNSRCGG. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F_02 | View Gene Set | 6.143e-07 | 169 | 9.214e-06 | 41 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTTSGCGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$USF_Q6_01 | View Gene Set | 6.39e-07 | 168 | 9.357e-06 | 42 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NRCCACGTGASN. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F_Q4_01 | View Gene Set | 8.576e-07 | 171 | 1.227e-05 | 43 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCSCGCSAAAN which matches annotation for E2F<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad V$MAX_01 | View Gene Set | 1.017e-06 | 194 | 1.422e-05 | 44 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNANCACGTGNTNN which matches annotation for MAX: MYC associated factor X | www.broad.mit.e... |
Broad V$E2F1DP1_01 | View Gene Set | 1.21e-06 | 169 | 1.583e-05 | 45 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad V$E2F1DP2_01 | View Gene Set | 1.21e-06 | 169 | 1.583e-05 | 45 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) | www.broad.mit.e... |
Broad V$E2F4DP2_01 | View Gene Set | 1.21e-06 | 169 | 1.583e-05 | 45 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2) | www.broad.mit.e... |
Broad V$E2F1DP1RB_01 | View Gene Set | 1.33e-06 | 168 | 1.704e-05 | 48 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma) | www.broad.mit.e... |
Broad V$USF_C | View Gene Set | 1.724e-06 | 211 | 2.164e-05 | 49 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NCACGTGN. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F1_Q3 | View Gene Set | 1.825e-06 | 176 | 2.245e-05 | 50 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NKTSSCGC which matches annotation for E2F1: E2F transcription factor 1 | www.broad.mit.e... |
Broad V$E2F1_Q4 | View Gene Set | 2.296e-06 | 178 | 2.747e-05 | 51 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTTSGCGG which matches annotation for E2F1: E2F transcription factor 1 | www.broad.mit.e... |
Broad GATGKMRGCG_UNKNOWN | View Gene Set | 2.323e-06 | 47 | 2.747e-05 | 51 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GATGKMRGCG. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$USF_02 | View Gene Set | 2.916e-06 | 197 | 3.321e-05 | 53 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNRNCACGTGNYNN. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad GCGNNANTTCC_UNKNOWN | View Gene Set | 2.863e-06 | 85 | 3.321e-05 | 53 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GCGNNANTTCC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$TEL2_Q6 | View Gene Set | 4.157e-06 | 158 | 4.648e-05 | 55 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif YTACTTCCTG which matches annotation for ETV7: ets variant gene 7 (TEL2 oncogene) | www.broad.mit.e... |
Broad V$USF_Q6 | View Gene Set | 4.698e-06 | 178 | 5.159e-05 | 56 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GYCACGTGNC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$E2F4DP1_01 | View Gene Set | 4.883e-06 | 174 | 5.261e-05 | 57 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F4: E2F transcription factor 4 p107/p130-binding<br> TFDP1: transcription factor Dp-1 | www.broad.mit.e... |
Broad YGCGYRCGC_UNKNOWN | View Gene Set | 4.962e-06 | 207 | 5.261e-05 | 57 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif YGCGYRCGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$CMYB_01 | View Gene Set | 8.558e-06 | 179 | 8.772e-05 | 59 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NCNRNNGRCNGTTGGKGG which matches annotation for MYB: v-myb myeloblastosis viral oncogene homolog (avian) | www.broad.mit.e... |
Broad GCGSCMNTTT_UNKNOWN | View Gene Set | 8.443e-06 | 49 | 8.772e-05 | 59 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GCGSCMNTTT. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$STAT1_02 | View Gene Set | 1.713e-05 | 179 | 0.0001727 | 61 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CANTTCCS which matches annotation for STAT1: signal transducer and activator of transcription 1 91kDa | www.broad.mit.e... |
Broad V$ARNT_01 | View Gene Set | 1.771e-05 | 196 | 0.0001757 | 62 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NDDNNCACGTGNNNNN which matches annotation for ARNT: aryl hydrocarbon receptor nuclear translocator | www.broad.mit.e... |
Broad RRCCGTTA_UNKNOWN | View Gene Set | 1.903e-05 | 53 | 0.0001857 | 63 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif RRCCGTTA. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad GGAANCGGAANY_UNKNOWN | View Gene Set | 2.747e-05 | 79 | 0.000264 | 64 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGAANCGGAANY. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$NMYC_01 | View Gene Set | 3.02e-05 | 201 | 0.0002857 | 65 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNCCACGTGNNN which matches annotation for MYCN: v-myc myelocytomatosis viral related oncogene neuroblastoma derived (avian) | www.broad.mit.e... |
Broad GGCNRNWCTTYS_UNKNOWN | View Gene Set | 3.845e-05 | 52 | 0.0003583 | 66 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGCNRNWCTTYS. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad CCGNMNNTNACG_UNKNOWN | View Gene Set | 5.416e-05 | 56 | 0.0004971 | 67 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CCGNMNNTNACG. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$HIF1_Q3 | View Gene Set | 6.299e-05 | 161 | 0.0005697 | 68 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GNNKACGTGCGGNN which matches annotation for HIF1A: hypoxia-inducible factor 1 alpha subunit (basic helix-loop-helix transcription factor) | www.broad.mit.e... |
Broad AAGWWRNYGGC_UNKNOWN | View Gene Set | 8.614e-05 | 85 | 0.0007678 | 69 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif AAGWWRNYGGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$USF2_Q6 | View Gene Set | 9.334e-05 | 182 | 0.0008201 | 70 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CASGYG. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad TTCNRGNNNNTTC_V$HSF_Q6 | View Gene Set | 9.598e-05 | 111 | 0.0008313 | 71 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTCNRGNNNNTTC. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$CREB_02 | View Gene Set | 9.998e-05 | 185 | 0.000854 | 72 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNGNTGACGTNN which matches annotation for CREB1: cAMP responsive element binding protein 1 | www.broad.mit.e... |
Broad CRGAARNNNNCGA_UNKNOWN | View Gene Set | 0.00012 | 34 | 0.001011 | 73 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CRGAARNNNNCGA. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$MYCMAX_03 | View Gene Set | 0.0001274 | 187 | 0.001059 | 74 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNNNCACGTGNNNNNNN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X | www.broad.mit.e... |
Broad V$YY1_01 | View Gene Set | 0.0002278 | 190 | 0.001868 | 75 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNCCATNTWNNNWN which matches annotation for YY1: YY1 transcription factor | www.broad.mit.e... |
Broad KTGGYRSGAA_UNKNOWN | View Gene Set | 0.0003041 | 53 | 0.002461 | 76 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif KTGGYRSGAA. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad GKCGCNNNNNNNTGAYG_UNKNOWN | View Gene Set | 0.0004081 | 41 | 0.00326 | 77 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GKCGCNNNNNNNTGAYG. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$NFY_Q6_01 | View Gene Set | 0.000448 | 185 | 0.003514 | 78 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NNNNRRCCAATSR. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad TGACCTY_V$ERR1_Q2 | View Gene Set | 0.0004514 | 772 | 0.003514 | 78 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TGACCTY which matches annotation for ESRRA: estrogen-related receptor alpha | www.broad.mit.e... |
Broad V$AHR_Q5 | View Gene Set | 0.0005865 | 153 | 0.004509 | 80 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NTNGCGTGNNN which matches annotation for AHR: aryl hydrocarbon receptor | www.broad.mit.e... |
Broad ATCMNTCCGY_UNKNOWN | View Gene Set | 0.0006883 | 36 | 0.005226 | 81 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ATCMNTCCGY. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$MYCMAX_02 | View Gene Set | 0.0007303 | 201 | 0.005477 | 82 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NANCACGTGNNW which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X | www.broad.mit.e... |
Broad TTCYRGAA_UNKNOWN | View Gene Set | 0.0009091 | 221 | 0.006736 | 83 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TTCYRGAA. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$MYCMAX_B | View Gene Set | 0.001111 | 193 | 0.008135 | 84 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GCCAYGYGSN which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian)<br> MAX: MYC associated factor X | www.broad.mit.e... |
Broad V$E2F_01 | View Gene Set | 0.001298 | 55 | 0.009391 | 85 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif TWSGCGCGAAAAYKR. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad ATGGYGGA_UNKNOWN | View Gene Set | 0.001519 | 68 | 0.01086 | 86 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif ATGGYGGA. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad CGTSACG_V$PAX3_B | View Gene Set | 0.001711 | 99 | 0.01209 | 87 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CGTSACG which matches annotation for PAX3: paired box gene 3 (Waardenburg syndrome 1) | www.broad.mit.e... |
Broad V$MYC_Q2 | View Gene Set | 0.001881 | 135 | 0.01314 | 88 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CACGTGS which matches annotation for MYC: v-myc myelocytomatosis viral oncogene homolog (avian) | www.broad.mit.e... |
Broad V$E4F1_Q6 | View Gene Set | 0.00238 | 203 | 0.01645 | 89 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif SYTACGTCAC which matches annotation for E4F1: E4F transcription factor 1 | www.broad.mit.e... |
Broad CTTTGT_V$LEF1_Q2 | View Gene Set | 0.002794 | 1458 | 0.01909 | 90 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CTTTGT which matches annotation for LEF1: lymphoid enhancer-binding factor 1 | www.broad.mit.e... |
Broad CCCNNNNNNAAGWT_UNKNOWN | View Gene Set | 0.002974 | 74 | 0.0201 | 91 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CCCNNNNNNAAGWT. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad GGGNRMNNYCAT_UNKNOWN | View Gene Set | 0.004407 | 61 | 0.0292 | 92 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGGNRMNNYCAT. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad YGCANTGCR_UNKNOWN | View Gene Set | 0.004415 | 93 | 0.0292 | 92 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif YGCANTGCR. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$ATF4_Q2 | View Gene Set | 0.004475 | 188 | 0.02928 | 94 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif CVTGACGYMABG which matches annotation for ATF4: activating transcription factor 4 (tax-responsive enhancer element B67) | www.broad.mit.e... |
Broad V$PR_01 | View Gene Set | 0.004814 | 109 | 0.03116 | 95 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNNNNGGNACRNNNTGTTCTNNNNNN which matches annotation for PGR: progesterone receptor | www.broad.mit.e... |
Broad V$NFY_C | View Gene Set | 0.005334 | 179 | 0.03417 | 96 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif NCTGATTGGYTASY. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$STAT1_01 | View Gene Set | 0.005571 | 49 | 0.03496 | 97 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif NNNSANTTCCGGGAANTGNSN which matches annotation for STAT1: signal transducer and activator of transcription 1 91kDa | www.broad.mit.e... |
Broad TGACCTTG_V$SF1_Q6 | View Gene Set | 0.005534 | 188 | 0.03496 | 97 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif TGACCTTG which matches annotation for SF1: splicing factor 1 | www.broad.mit.e... |
Broad GGAMTNNNNNTCCY_UNKNOWN | View Gene Set | 0.007082 | 85 | 0.044 | 99 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif GGAMTNNNNNTCCY. Motif does not match any known transcription factor | www.broad.mit.e... |
Broad V$SP1_01 | View Gene Set | 0.007785 | 181 | 0.04788 | 100 | Genes with promoter regions [-2kb 2kb] around transcription start site containing the motif GGGGCGGGGT which matches annotation for SP1: Sp1 transcription factor | www.broad.mit.e... |
Broad CCAWNWWNNNGGC_UNKNOWN | View Gene Set | 0.008084 | 56 | 0.04922 | 101 | Genes with promoter regions [-2kb 2kb] around transcription start site containing motif CCAWNWWNNNGGC. Motif does not match any known transcription factor | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad MORF_RAD23A | View Gene Set | 1.961e-84 | 316 | 8.375e-82 | 1 | Neighborhood of RAD23A | www.broad.mit.e... |
Broad MORF_BUB3 | View Gene Set | 1.949e-76 | 256 | 4.161e-74 | 2 | Neighborhood of BUB3 | www.broad.mit.e... |
Broad MORF_GNB1 | View Gene Set | 3.724e-76 | 276 | 5.301e-74 | 3 | Neighborhood of GNB1 | www.broad.mit.e... |
Broad MORF_RAN | View Gene Set | 1.121e-74 | 242 | 1.197e-72 | 4 | Neighborhood of RAN | www.broad.mit.e... |
Broad MORF_UBE2I | View Gene Set | 2.804e-71 | 208 | 2.394e-69 | 5 | Neighborhood of UBE2I | www.broad.mit.e... |
Broad MORF_DEK | View Gene Set | 2.718e-69 | 229 | 1.934e-67 | 6 | Neighborhood of DEK | www.broad.mit.e... |
Broad MORF_HDAC2 | View Gene Set | 7.245e-66 | 256 | 4.419e-64 | 7 | Neighborhood of HDAC2 | www.broad.mit.e... |
Broad MORF_SOD1 | View Gene Set | 5.192e-65 | 247 | 2.474e-63 | 8 | Neighborhood of SOD1 | www.broad.mit.e... |
Broad MORF_CSNK2B | View Gene Set | 5.215e-65 | 256 | 2.474e-63 | 8 | Neighborhood of CSNK2B | www.broad.mit.e... |
Broad MORF_HDAC1 | View Gene Set | 5.06e-64 | 222 | 2.161e-62 | 10 | Neighborhood of HDAC1 | www.broad.mit.e... |
Broad MORF_EIF3S2 | View Gene Set | 2.56e-63 | 220 | 9.939e-62 | 11 | Neighborhood of EIF3S2 | www.broad.mit.e... |
Broad MORF_ACP1 | View Gene Set | 1.916e-59 | 178 | 6.817e-58 | 12 | Neighborhood of ACP1 | www.broad.mit.e... |
Broad MORF_ANP32B | View Gene Set | 2.965e-59 | 174 | 9.739e-58 | 13 | Neighborhood of ANP32B | www.broad.mit.e... |
Broad MORF_XRCC5 | View Gene Set | 6.781e-58 | 210 | 2.068e-56 | 14 | Neighborhood of XRCC5 | www.broad.mit.e... |
Broad MORF_NPM1 | View Gene Set | 1.103e-57 | 152 | 3.14e-56 | 15 | Neighborhood of NPM1 | www.broad.mit.e... |
Broad MORF_NME2 | View Gene Set | 3.34e-52 | 145 | 8.912e-51 | 16 | Neighborhood of NME2 | www.broad.mit.e... |
Broad MORF_DAP3 | View Gene Set | 4.941e-52 | 175 | 1.241e-50 | 17 | Neighborhood of DAP3 | www.broad.mit.e... |
Broad MORF_AP2M1 | View Gene Set | 3.039e-51 | 197 | 7.21e-50 | 18 | Neighborhood of AP2M1 | www.broad.mit.e... |
Broad MORF_ACTG1 | View Gene Set | 1.118e-50 | 134 | 2.513e-49 | 19 | Neighborhood of ACTG1 | www.broad.mit.e... |
Broad MORF_PRKDC | View Gene Set | 3.866e-49 | 173 | 8.254e-48 | 20 | Neighborhood of PRKDC | www.broad.mit.e... |
Broad MORF_G22P1 | View Gene Set | 2.901e-48 | 145 | 5.898e-47 | 21 | Neighborhood of G22P1 | www.broad.mit.e... |
Broad MORF_AATF | View Gene Set | 9.457e-48 | 179 | 1.835e-46 | 22 | Neighborhood of AATF | www.broad.mit.e... |
Broad MORF_CTBP1 | View Gene Set | 2.009e-47 | 149 | 3.73e-46 | 23 | Neighborhood of CTBP1 | www.broad.mit.e... |
Broad MORF_SKP1A | View Gene Set | 2.69e-47 | 175 | 4.786e-46 | 24 | Neighborhood of SKP1A | www.broad.mit.e... |
Broad MORF_PRKAG1 | View Gene Set | 7.006e-47 | 202 | 1.197e-45 | 25 | Neighborhood of PRKAG1 | www.broad.mit.e... |
Broad MORF_HAT1 | View Gene Set | 1.976e-46 | 155 | 3.245e-45 | 26 | Neighborhood of HAT1 | www.broad.mit.e... |
Broad MORF_PPP1CC | View Gene Set | 2.448e-46 | 150 | 3.872e-45 | 27 | Neighborhood of PPP1CC | www.broad.mit.e... |
Broad MORF_RAD21 | View Gene Set | 9.345e-46 | 157 | 1.425e-44 | 28 | Neighborhood of RAD21 | www.broad.mit.e... |
Broad MORF_RAC1 | View Gene Set | 1.167e-43 | 196 | 1.718e-42 | 29 | Neighborhood of RAC1 | www.broad.mit.e... |
Broad MORF_EIF4A2 | View Gene Set | 1.012e-42 | 120 | 1.441e-41 | 30 | Neighborhood of EIF4A2 | www.broad.mit.e... |
Broad MORF_FBL | View Gene Set | 1.002e-41 | 121 | 1.38e-40 | 31 | Neighborhood of FBL | www.broad.mit.e... |
Broad MORF_EI24 | View Gene Set | 2.657e-41 | 136 | 3.546e-40 | 32 | Neighborhood of EI24 | www.broad.mit.e... |
Broad MORF_PPP1CA | View Gene Set | 1.855e-40 | 145 | 2.4e-39 | 33 | Neighborhood of PPP1CA | www.broad.mit.e... |
Broad MORF_PRKAR1A | View Gene Set | 3.5e-40 | 133 | 4.395e-39 | 34 | Neighborhood of PRKAR1A | www.broad.mit.e... |
Broad GNF2_FBL | View Gene Set | 6.543e-40 | 119 | 7.982e-39 | 35 | Neighborhood of FBL | www.broad.mit.e... |
Broad MORF_DDB1 | View Gene Set | 4.131e-39 | 220 | 4.9e-38 | 36 | Neighborhood of DDB1 | www.broad.mit.e... |
Broad MORF_EIF3S6 | View Gene Set | 1.176e-38 | 108 | 1.357e-37 | 37 | Neighborhood of EIF3S6 | www.broad.mit.e... |
Broad GCM_APEX1 | View Gene Set | 2.049e-38 | 102 | 2.302e-37 | 38 | Neighborhood of APEX1 | www.broad.mit.e... |
Broad MORF_PSMC1 | View Gene Set | 3.518e-38 | 162 | 3.852e-37 | 39 | Neighborhood of PSMC1 | www.broad.mit.e... |
Broad MORF_RFC4 | View Gene Set | 1.353e-37 | 137 | 1.444e-36 | 40 | Neighborhood of RFC4 | www.broad.mit.e... |
Broad MORF_RAD23B | View Gene Set | 2.107e-37 | 159 | 2.195e-36 | 41 | Neighborhood of RAD23B | www.broad.mit.e... |
Broad GNF2_EIF3S6 | View Gene Set | 3.149e-37 | 109 | 3.201e-36 | 42 | Neighborhood of EIF3S6 | www.broad.mit.e... |
Broad GCM_ACTG1 | View Gene Set | 6.233e-36 | 113 | 6.189e-35 | 43 | Neighborhood of ACTG1 | www.broad.mit.e... |
Broad MORF_TPT1 | View Gene Set | 2.823e-35 | 100 | 2.74e-34 | 44 | Neighborhood of TPT1 | www.broad.mit.e... |
Broad MORF_AP3D1 | View Gene Set | 5.346e-35 | 119 | 5.073e-34 | 45 | Neighborhood of AP3D1 | www.broad.mit.e... |
Broad MORF_ERH | View Gene Set | 2.28e-34 | 103 | 2.116e-33 | 46 | Neighborhood of ERH | www.broad.mit.e... |
Broad GCM_NPM1 | View Gene Set | 5.013e-34 | 108 | 4.555e-33 | 47 | Neighborhood of NPM1 | www.broad.mit.e... |
Broad MORF_RPA2 | View Gene Set | 2.506e-33 | 170 | 2.23e-32 | 48 | Neighborhood of RPA2 | www.broad.mit.e... |
Broad MORF_RAB1A | View Gene Set | 8.854e-33 | 179 | 7.715e-32 | 49 | Neighborhood of RAB1A | www.broad.mit.e... |
Broad MORF_DNMT1 | View Gene Set | 1.664e-32 | 105 | 1.421e-31 | 50 | Neighborhood of DNMT1 | www.broad.mit.e... |
Broad GCM_CSNK2B | View Gene Set | 1.165e-31 | 88 | 9.758e-31 | 51 | Neighborhood of CSNK2B | www.broad.mit.e... |
Broad MORF_CCNI | View Gene Set | 2.703e-31 | 76 | 2.22e-30 | 52 | Neighborhood of CCNI | www.broad.mit.e... |
Broad GNF2_DAP3 | View Gene Set | 4.011e-31 | 98 | 3.232e-30 | 53 | Neighborhood of DAP3 | www.broad.mit.e... |
Broad MORF_PAPSS1 | View Gene Set | 2.772e-30 | 98 | 2.192e-29 | 54 | Neighborhood of PAPSS1 | www.broad.mit.e... |
Broad MORF_PPP2CA | View Gene Set | 1.811e-29 | 110 | 1.406e-28 | 55 | Neighborhood of PPP2CA | www.broad.mit.e... |
Broad GNF2_PA2G4 | View Gene Set | 2.901e-29 | 73 | 2.212e-28 | 56 | Neighborhood of PA2G4 | www.broad.mit.e... |
Broad MORF_PCNA | View Gene Set | 2.382e-28 | 71 | 1.784e-27 | 57 | Neighborhood of PCNA | www.broad.mit.e... |
Broad MORF_RRM1 | View Gene Set | 5.022e-28 | 90 | 3.697e-27 | 58 | Neighborhood of RRM1 | www.broad.mit.e... |
Broad MORF_MAP2K2 | View Gene Set | 1.67e-27 | 123 | 1.209e-26 | 59 | Neighborhood of MAP2K2 | www.broad.mit.e... |
Broad GNF2_RAN | View Gene Set | 1.797e-27 | 78 | 1.279e-26 | 60 | Neighborhood of RAN | www.broad.mit.e... |
Broad MORF_CDC10 | View Gene Set | 1.921e-27 | 120 | 1.345e-26 | 61 | Neighborhood of CDC10 | www.broad.mit.e... |
Broad GCM_PSME1 | View Gene Set | 8.096e-27 | 76 | 5.576e-26 | 62 | Neighborhood of PSME1 | www.broad.mit.e... |
Broad GCM_TPT1 | View Gene Set | 2.54e-25 | 69 | 1.721e-24 | 63 | Neighborhood of TPT1 | www.broad.mit.e... |
Broad GNF2_APEX1 | View Gene Set | 4.381e-25 | 72 | 2.923e-24 | 64 | Neighborhood of APEX1 | www.broad.mit.e... |
Broad GNF2_RRM1 | View Gene Set | 1.213e-24 | 82 | 7.97e-24 | 65 | Neighborhood of RRM1 | www.broad.mit.e... |
Broad MORF_RAD54L | View Gene Set | 4.372e-24 | 94 | 2.828e-23 | 66 | Neighborhood of RAD54L | www.broad.mit.e... |
Broad MORF_SP3 | View Gene Set | 4.854e-24 | 69 | 3.056e-23 | 67 | Neighborhood of SP3 | www.broad.mit.e... |
Broad GCM_CBFB | View Gene Set | 4.867e-24 | 59 | 3.056e-23 | 67 | Neighborhood of CBFB | www.broad.mit.e... |
Broad MORF_UBE2N | View Gene Set | 1.413e-22 | 79 | 8.747e-22 | 69 | Neighborhood of UBE2N | www.broad.mit.e... |
Broad MORF_JUND | View Gene Set | 1.847e-22 | 63 | 1.127e-21 | 70 | Neighborhood of JUND | www.broad.mit.e... |
Broad MORF_MTA1 | View Gene Set | 1.917e-22 | 95 | 1.153e-21 | 71 | Neighborhood of MTA1 | www.broad.mit.e... |
Broad MORF_PSMC2 | View Gene Set | 2.372e-22 | 100 | 1.407e-21 | 72 | Neighborhood of PSMC2 | www.broad.mit.e... |
Broad GNF2_ST13 | View Gene Set | 2.472e-22 | 56 | 1.446e-21 | 73 | Neighborhood of ST13 | www.broad.mit.e... |
Broad MORF_PTPN11 | View Gene Set | 1.484e-21 | 93 | 8.565e-21 | 74 | Neighborhood of PTPN11 | www.broad.mit.e... |
Broad MORF_RAF1 | View Gene Set | 1.573e-21 | 94 | 8.953e-21 | 75 | Neighborhood of RAF1 | www.broad.mit.e... |
Broad GNF2_NPM1 | View Gene Set | 2.407e-21 | 57 | 1.352e-20 | 76 | Neighborhood of NPM1 | www.broad.mit.e... |
Broad MORF_UNG | View Gene Set | 7.455e-21 | 65 | 4.134e-20 | 77 | Neighborhood of UNG | www.broad.mit.e... |
Broad MORF_PRDX3 | View Gene Set | 1.773e-20 | 79 | 9.704e-20 | 78 | Neighborhood of PRDX3 | www.broad.mit.e... |
Broad MORF_RAB6A | View Gene Set | 5.276e-20 | 63 | 2.852e-19 | 79 | Neighborhood of RAB6A | www.broad.mit.e... |
Broad GNF2_SMC4L1 | View Gene Set | 7.136e-20 | 75 | 3.809e-19 | 80 | Neighborhood of SMC4L1 | www.broad.mit.e... |
Broad MORF_SART1 | View Gene Set | 2.037e-19 | 55 | 1.074e-18 | 81 | Neighborhood of SART1 | www.broad.mit.e... |
Broad MORF_ATOX1 | View Gene Set | 2.126e-19 | 72 | 1.107e-18 | 82 | Neighborhood of ATOX1 | www.broad.mit.e... |
Broad MORF_ESPL1 | View Gene Set | 4.779e-19 | 58 | 2.459e-18 | 83 | Neighborhood of ESPL1 | www.broad.mit.e... |
Broad MORF_PHB | View Gene Set | 7.265e-19 | 112 | 3.693e-18 | 84 | Neighborhood of PHB | www.broad.mit.e... |
Broad MORF_FEN1 | View Gene Set | 9.517e-19 | 58 | 4.781e-18 | 85 | Neighborhood of FEN1 | www.broad.mit.e... |
Broad GCM_PPP1CC | View Gene Set | 1.381e-18 | 47 | 6.855e-18 | 86 | Neighborhood of PPP1CC | www.broad.mit.e... |
Broad MORF_CUL1 | View Gene Set | 2.01e-18 | 62 | 9.867e-18 | 87 | Neighborhood of CUL1 | www.broad.mit.e... |
Broad MORF_MBD4 | View Gene Set | 2.386e-18 | 76 | 1.158e-17 | 88 | Neighborhood of MBD4 | www.broad.mit.e... |
Broad MORF_TERF2IP | View Gene Set | 2.545e-18 | 99 | 1.221e-17 | 89 | Neighborhood of TERF2IP | www.broad.mit.e... |
Broad GNF2_CDC20 | View Gene Set | 3.999e-18 | 52 | 1.897e-17 | 90 | Neighborhood of CDC20 | www.broad.mit.e... |
Broad MORF_CDC16 | View Gene Set | 4.173e-18 | 67 | 1.937e-17 | 91 | Neighborhood of CDC16 | www.broad.mit.e... |
Broad MORF_CDK2 | View Gene Set | 4.163e-18 | 63 | 1.937e-17 | 91 | Neighborhood of CDK2 | www.broad.mit.e... |
Broad MORF_SMC1L1 | View Gene Set | 5.635e-18 | 47 | 2.587e-17 | 93 | Neighborhood of SMC1L1 | www.broad.mit.e... |
Broad GNF2_HAT1 | View Gene Set | 1.184e-17 | 45 | 5.376e-17 | 94 | Neighborhood of HAT1 | www.broad.mit.e... |
Broad GNF2_MCM5 | View Gene Set | 1.298e-17 | 51 | 5.836e-17 | 95 | Neighborhood of MCM5 | www.broad.mit.e... |
Broad GNF2_CCNA2 | View Gene Set | 2.237e-17 | 62 | 9.95e-17 | 96 | Neighborhood of CCNA2 | www.broad.mit.e... |
Broad GCM_NF2 | View Gene Set | 2.323e-17 | 235 | 1.012e-16 | 97 | Neighborhood of NF2 | www.broad.mit.e... |
Broad GNF2_RFC4 | View Gene Set | 2.32e-17 | 57 | 1.012e-16 | 97 | Neighborhood of RFC4 | www.broad.mit.e... |
Broad MORF_SNRP70 | View Gene Set | 2.464e-17 | 50 | 1.063e-16 | 99 | Neighborhood of SNRP70 | www.broad.mit.e... |
Broad MORF_BUB1 | View Gene Set | 3.837e-17 | 49 | 1.638e-16 | 100 | Neighborhood of BUB1 | www.broad.mit.e... |
Broad GCM_DDX5 | View Gene Set | 4.257e-17 | 52 | 1.8e-16 | 101 | Neighborhood of DDX5 | www.broad.mit.e... |
Broad MORF_TERF1 | View Gene Set | 4.805e-17 | 57 | 2.012e-16 | 102 | Neighborhood of TERF1 | www.broad.mit.e... |
Broad GNF2_XRCC5 | View Gene Set | 5.498e-17 | 61 | 2.279e-16 | 103 | Neighborhood of XRCC5 | www.broad.mit.e... |
Broad GCM_PFN1 | View Gene Set | 8.456e-17 | 47 | 3.472e-16 | 104 | Neighborhood of PFN1 | www.broad.mit.e... |
Broad MORF_DEAF1 | View Gene Set | 1.078e-16 | 54 | 4.382e-16 | 105 | Neighborhood of DEAF1 | www.broad.mit.e... |
Broad GNF2_CCNB2 | View Gene Set | 1.408e-16 | 53 | 5.674e-16 | 106 | Neighborhood of CCNB2 | www.broad.mit.e... |
Broad GNF2_PCNA | View Gene Set | 1.439e-16 | 62 | 5.743e-16 | 107 | Neighborhood of PCNA | www.broad.mit.e... |
Broad MORF_MSH2 | View Gene Set | 3.12e-16 | 52 | 1.228e-15 | 108 | Neighborhood of MSH2 | www.broad.mit.e... |
Broad MORF_RPA1 | View Gene Set | 3.134e-16 | 55 | 1.228e-15 | 108 | Neighborhood of RPA1 | www.broad.mit.e... |
Broad GNF2_DEK | View Gene Set | 6.008e-16 | 45 | 2.332e-15 | 110 | Neighborhood of DEK | www.broad.mit.e... |
Broad GNF2_HDAC1 | View Gene Set | 7.371e-16 | 85 | 2.836e-15 | 111 | Neighborhood of HDAC1 | www.broad.mit.e... |
Broad GNF2_MCM4 | View Gene Set | 8.161e-16 | 50 | 3.111e-15 | 112 | Neighborhood of MCM4 | www.broad.mit.e... |
Broad MORF_BMI1 | View Gene Set | 1.345e-15 | 71 | 5.084e-15 | 113 | Neighborhood of BMI1 | www.broad.mit.e... |
Broad MORF_BUB1B | View Gene Set | 1.416e-15 | 61 | 5.305e-15 | 114 | Neighborhood of BUB1B | www.broad.mit.e... |
Broad MORF_RAB5A | View Gene Set | 1.555e-15 | 83 | 5.773e-15 | 115 | Neighborhood of RAB5A | www.broad.mit.e... |
Broad GNF2_CENPF | View Gene Set | 1.727e-15 | 56 | 6.356e-15 | 116 | Neighborhood of CENPF | www.broad.mit.e... |
Broad GNF2_FEN1 | View Gene Set | 6.648e-15 | 49 | 2.426e-14 | 117 | Neighborhood of FEN1 | www.broad.mit.e... |
Broad MORF_BECN1 | View Gene Set | 7.222e-15 | 93 | 2.614e-14 | 118 | Neighborhood of BECN1 | www.broad.mit.e... |
Broad MORF_GMPS | View Gene Set | 8.479e-15 | 48 | 3.042e-14 | 119 | Neighborhood of GMPS | www.broad.mit.e... |
Broad GNF2_HMMR | View Gene Set | 1.22e-14 | 43 | 4.34e-14 | 120 | Neighborhood of HMMR | www.broad.mit.e... |
Broad GCM_RAB10 | View Gene Set | 1.474e-14 | 143 | 5.2e-14 | 121 | Neighborhood of RAB10 | www.broad.mit.e... |
Broad GNF2_NS | View Gene Set | 2.091e-14 | 35 | 7.317e-14 | 122 | Neighborhood of NS | www.broad.mit.e... |
Broad MORF_BAG5 | View Gene Set | 3.218e-14 | 48 | 1.117e-13 | 123 | Neighborhood of BAG5 | www.broad.mit.e... |
Broad MORF_XPC | View Gene Set | 3.461e-14 | 55 | 1.192e-13 | 124 | Neighborhood of XPC | www.broad.mit.e... |
Broad GNF2_BUB1B | View Gene Set | 3.978e-14 | 46 | 1.359e-13 | 125 | Neighborhood of BUB1B | www.broad.mit.e... |
Broad GNF2_TPT1 | View Gene Set | 1.074e-13 | 38 | 3.639e-13 | 126 | Neighborhood of TPT1 | www.broad.mit.e... |
Broad MORF_PPP6C | View Gene Set | 1.157e-13 | 88 | 3.89e-13 | 127 | Neighborhood of PPP6C | www.broad.mit.e... |
Broad GNF2_CDC2 | View Gene Set | 1.279e-13 | 56 | 4.267e-13 | 128 | Neighborhood of CDC2 | www.broad.mit.e... |
Broad MORF_DAP | View Gene Set | 1.486e-13 | 72 | 4.92e-13 | 129 | Neighborhood of DAP | www.broad.mit.e... |
Broad GCM_ANP32B | View Gene Set | 1.789e-13 | 32 | 5.877e-13 | 130 | Neighborhood of ANP32B | www.broad.mit.e... |
Broad GNF2_RRM2 | View Gene Set | 2.049e-13 | 36 | 6.68e-13 | 131 | Neighborhood of RRM2 | www.broad.mit.e... |
Broad GNF2_MLH1 | View Gene Set | 2.135e-13 | 36 | 6.905e-13 | 132 | Neighborhood of MLH1 | www.broad.mit.e... |
Broad MORF_PPP2R4 | View Gene Set | 2.168e-13 | 44 | 6.961e-13 | 133 | Neighborhood of PPP2R4 | www.broad.mit.e... |
Broad GNF2_DENR | View Gene Set | 2.4e-13 | 39 | 7.649e-13 | 134 | Neighborhood of DENR | www.broad.mit.e... |
Broad GCM_RAF1 | View Gene Set | 2.475e-13 | 34 | 7.827e-13 | 135 | Neighborhood of RAF1 | www.broad.mit.e... |
Broad MORF_GPX4 | View Gene Set | 2.557e-13 | 49 | 8.029e-13 | 136 | Neighborhood of GPX4 | www.broad.mit.e... |
Broad GCM_GSPT1 | View Gene Set | 3.875e-13 | 129 | 1.208e-12 | 137 | Neighborhood of GSPT1 | www.broad.mit.e... |
Broad GNF2_CKS2 | View Gene Set | 7.05e-13 | 45 | 2.181e-12 | 138 | Neighborhood of CKS2 | www.broad.mit.e... |
Broad GCM_HDAC1 | View Gene Set | 1.242e-12 | 30 | 3.815e-12 | 139 | Neighborhood of HDAC1 | www.broad.mit.e... |
Broad GNF2_MSH6 | View Gene Set | 2.367e-12 | 30 | 7.22e-12 | 140 | Neighborhood of MSH6 | www.broad.mit.e... |
Broad GNF2_RFC3 | View Gene Set | 2.437e-12 | 38 | 7.38e-12 | 141 | Neighborhood of RFC3 | www.broad.mit.e... |
Broad MORF_TPR | View Gene Set | 2.847e-12 | 131 | 8.561e-12 | 142 | Neighborhood of TPR | www.broad.mit.e... |
Broad GNF2_CKS1B | View Gene Set | 3.981e-12 | 36 | 1.189e-11 | 143 | Neighborhood of CKS1B | www.broad.mit.e... |
Broad GCM_UBE2N | View Gene Set | 5.229e-12 | 125 | 1.551e-11 | 144 | Neighborhood of UBE2N | www.broad.mit.e... |
Broad GNF2_ESPL1 | View Gene Set | 5.416e-12 | 35 | 1.595e-11 | 145 | Neighborhood of ESPL1 | www.broad.mit.e... |
Broad MORF_EIF4E | View Gene Set | 7.327e-12 | 76 | 2.143e-11 | 146 | Neighborhood of EIF4E | www.broad.mit.e... |
Broad GCM_RAD21 | View Gene Set | 8.003e-12 | 30 | 2.325e-11 | 147 | Neighborhood of RAD21 | www.broad.mit.e... |
Broad GCM_DFFA | View Gene Set | 1.111e-11 | 100 | 3.206e-11 | 148 | Neighborhood of DFFA | www.broad.mit.e... |
Broad GNF2_UBE2I | View Gene Set | 1.547e-11 | 33 | 4.434e-11 | 149 | Neighborhood of UBE2I | www.broad.mit.e... |
Broad MORF_GSPT1 | View Gene Set | 1.902e-11 | 41 | 5.415e-11 | 150 | Neighborhood of GSPT1 | www.broad.mit.e... |
Broad GCM_MYST2 | View Gene Set | 2.029e-11 | 138 | 5.738e-11 | 151 | Neighborhood of MYST2 | www.broad.mit.e... |
Broad GNF2_TTK | View Gene Set | 3.01e-11 | 34 | 8.455e-11 | 152 | Neighborhood of TTK | www.broad.mit.e... |
Broad GNF2_CENPE | View Gene Set | 3.589e-11 | 37 | 1.002e-10 | 153 | Neighborhood of CENPE | www.broad.mit.e... |
Broad GNF2_KPNB1 | View Gene Set | 4.404e-11 | 52 | 1.221e-10 | 154 | Neighborhood of KPNB1 | www.broad.mit.e... |
Broad MORF_PPP2R5E | View Gene Set | 4.579e-11 | 76 | 1.261e-10 | 155 | Neighborhood of PPP2R5E | www.broad.mit.e... |
Broad MORF_UBE2A | View Gene Set | 5.001e-11 | 44 | 1.369e-10 | 156 | Neighborhood of UBE2A | www.broad.mit.e... |
Broad GNF2_GLTSCR2 | View Gene Set | 5.711e-11 | 31 | 1.553e-10 | 157 | Neighborhood of GLTSCR2 | www.broad.mit.e... |
Broad MORF_RFC1 | View Gene Set | 6.604e-11 | 98 | 1.785e-10 | 158 | Neighborhood of RFC1 | www.broad.mit.e... |
Broad GNF2_G22P1 | View Gene Set | 1.181e-10 | 29 | 3.171e-10 | 159 | Neighborhood of G22P1 | www.broad.mit.e... |
Broad GCM_HBP1 | View Gene Set | 1.993e-10 | 54 | 5.319e-10 | 160 | Neighborhood of HBP1 | www.broad.mit.e... |
Broad GNF2_BUB3 | View Gene Set | 7.698e-10 | 22 | 2.042e-09 | 161 | Neighborhood of BUB3 | www.broad.mit.e... |
Broad GNF2_RBBP6 | View Gene Set | 8.288e-10 | 54 | 2.185e-09 | 162 | Neighborhood of RBBP6 | www.broad.mit.e... |
Broad GNF2_SMC2L1 | View Gene Set | 1.113e-09 | 30 | 2.914e-09 | 163 | Neighborhood of SMC2L1 | www.broad.mit.e... |
Broad GNF2_ANP32B | View Gene Set | 1.44e-09 | 29 | 3.749e-09 | 164 | Neighborhood of ANP32B | www.broad.mit.e... |
Broad GNF2_MSH2 | View Gene Set | 1.719e-09 | 26 | 4.45e-09 | 165 | Neighborhood of MSH2 | www.broad.mit.e... |
Broad GNF2_H2AFX | View Gene Set | 1.956e-09 | 28 | 5.032e-09 | 166 | Neighborhood of H2AFX | www.broad.mit.e... |
Broad GCM_SMARCC1 | View Gene Set | 2.281e-09 | 33 | 5.832e-09 | 167 | Neighborhood of SMARCC1 | www.broad.mit.e... |
Broad MORF_USP5 | View Gene Set | 2.419e-09 | 46 | 6.148e-09 | 168 | Neighborhood of USP5 | www.broad.mit.e... |
Broad GCM_BMPR2 | View Gene Set | 2.777e-09 | 68 | 7.016e-09 | 169 | Neighborhood of BMPR2 | www.broad.mit.e... |
Broad GCM_DENR | View Gene Set | 4.246e-09 | 40 | 1.067e-08 | 170 | Neighborhood of DENR | www.broad.mit.e... |
Broad GCM_MLL | View Gene Set | 4.367e-09 | 130 | 1.091e-08 | 171 | Neighborhood of MLL | www.broad.mit.e... |
Broad GNF2_BUB1 | View Gene Set | 4.485e-09 | 25 | 1.114e-08 | 172 | Neighborhood of BUB1 | www.broad.mit.e... |
Broad GNF2_PPP6C | View Gene Set | 5.725e-09 | 33 | 1.413e-08 | 173 | Neighborhood of PPP6C | www.broad.mit.e... |
Broad GNF2_TDG | View Gene Set | 6.614e-09 | 23 | 1.623e-08 | 174 | Neighborhood of TDG | www.broad.mit.e... |
Broad MORF_IKBKG | View Gene Set | 7.008e-09 | 119 | 1.7e-08 | 175 | Neighborhood of IKBKG | www.broad.mit.e... |
Broad GCM_RAN | View Gene Set | 6.991e-09 | 160 | 1.7e-08 | 175 | Neighborhood of RAN | www.broad.mit.e... |
Broad GCM_TPR | View Gene Set | 1.024e-08 | 29 | 2.469e-08 | 177 | Neighborhood of TPR | www.broad.mit.e... |
Broad MORF_SS18 | View Gene Set | 2.046e-08 | 55 | 4.909e-08 | 178 | Neighborhood of SS18 | www.broad.mit.e... |
Broad GNF2_MKI67 | View Gene Set | 2.443e-08 | 26 | 5.827e-08 | 179 | Neighborhood of MKI67 | www.broad.mit.e... |
Broad MORF_CSNK1D | View Gene Set | 2.936e-08 | 65 | 6.964e-08 | 180 | Neighborhood of CSNK1D | www.broad.mit.e... |
Broad GCM_CSNK1A1 | View Gene Set | 6.755e-08 | 28 | 1.594e-07 | 181 | Neighborhood of CSNK1A1 | www.broad.mit.e... |
Broad GCM_ERBB2IP | View Gene Set | 9.648e-08 | 57 | 2.264e-07 | 182 | Neighborhood of ERBB2IP | www.broad.mit.e... |
Broad GCM_BCL2L1 | View Gene Set | 1.268e-07 | 25 | 2.959e-07 | 183 | Neighborhood of BCL2L1 | www.broad.mit.e... |
Broad GCM_CALM1 | View Gene Set | 1.48e-07 | 91 | 3.434e-07 | 184 | Neighborhood of CALM1 | www.broad.mit.e... |
Broad GCM_BECN1 | View Gene Set | 2.774e-07 | 59 | 6.403e-07 | 185 | Neighborhood of BECN1 | www.broad.mit.e... |
Broad GCM_CHUK | View Gene Set | 3.631e-07 | 61 | 8.336e-07 | 186 | Neighborhood of CHUK | www.broad.mit.e... |
Broad MORF_RAB11A | View Gene Set | 5.773e-07 | 53 | 1.318e-06 | 187 | Neighborhood of RAB11A | www.broad.mit.e... |
Broad GCM_RBM8A | View Gene Set | 6.66e-07 | 64 | 1.513e-06 | 188 | Neighborhood of RBM8A | www.broad.mit.e... |
Broad GCM_IL6ST | View Gene Set | 8.668e-07 | 48 | 1.958e-06 | 189 | Neighborhood of IL6ST | www.broad.mit.e... |
Broad GCM_MSN | View Gene Set | 8.893e-07 | 24 | 1.999e-06 | 190 | Neighborhood of MSN | www.broad.mit.e... |
Broad GNF2_SMC1L1 | View Gene Set | 1.646e-06 | 24 | 3.68e-06 | 191 | Neighborhood of SMC1L1 | www.broad.mit.e... |
Broad GCM_MAX | View Gene Set | 1.728e-06 | 28 | 3.844e-06 | 192 | Neighborhood of MAX | www.broad.mit.e... |
Broad GNF2_ELAC2 | View Gene Set | 1.741e-06 | 32 | 3.852e-06 | 193 | Neighborhood of ELAC2 | www.broad.mit.e... |
Broad MORF_CCNF | View Gene Set | 3.693e-06 | 65 | 8.129e-06 | 194 | Neighborhood of CCNF | www.broad.mit.e... |
Broad GCM_AIP | View Gene Set | 4.112e-06 | 36 | 9.004e-06 | 195 | Neighborhood of AIP | www.broad.mit.e... |
Broad MORF_ARAF1 | View Gene Set | 7.861e-06 | 70 | 1.713e-05 | 196 | Neighborhood of ARAF1 | www.broad.mit.e... |
Broad GCM_GSTA4 | View Gene Set | 8.191e-06 | 57 | 1.775e-05 | 197 | Neighborhood of GSTA4 | www.broad.mit.e... |
Broad MORF_ORC1L | View Gene Set | 1.684e-05 | 61 | 3.632e-05 | 198 | Neighborhood of ORC1L | www.broad.mit.e... |
Broad GNF2_BNIP2 | View Gene Set | 2.294e-05 | 31 | 4.923e-05 | 199 | Neighborhood of BNIP2 | www.broad.mit.e... |
Broad GNF2_CBFB | View Gene Set | 2.501e-05 | 26 | 5.34e-05 | 200 | Neighborhood of CBFB | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad module_83 | View Gene Set | 2.799e-76 | 296 | 1.271e-73 | 1 | Genes in module_83 | www.broad.mit.e... |
Broad module_114 | View Gene Set | 1.153e-66 | 314 | 2.618e-64 | 2 | Genes in module_114 | www.broad.mit.e... |
Broad module_151 | View Gene Set | 1.991e-62 | 297 | 3.013e-60 | 3 | Genes in module_151 | www.broad.mit.e... |
Broad module_32 | View Gene Set | 2.488e-56 | 227 | 2.824e-54 | 4 | Genes in module_32 | www.broad.mit.e... |
Broad module_8 | View Gene Set | 1.919e-38 | 403 | 1.742e-36 | 5 | Genes in module_8 | www.broad.mit.e... |
Broad module_17 | View Gene Set | 6.379e-36 | 351 | 4.827e-34 | 6 | Genes in module_17 | www.broad.mit.e... |
Broad module_98 | View Gene Set | 7.88e-34 | 375 | 5.111e-32 | 7 | Genes in module_98 | www.broad.mit.e... |
Broad module_198 | View Gene Set | 5.193e-31 | 288 | 2.947e-29 | 8 | Genes in module_198 | www.broad.mit.e... |
Broad module_3 | View Gene Set | 4.552e-26 | 374 | 2.296e-24 | 9 | Genes in module_3 | www.broad.mit.e... |
Broad module_54 | View Gene Set | 2.68e-25 | 242 | 1.217e-23 | 10 | Genes in module_54 | www.broad.mit.e... |
Broad module_252 | View Gene Set | 4.661e-24 | 224 | 1.924e-22 | 11 | Genes in module_252 | www.broad.mit.e... |
Broad module_152 | View Gene Set | 1.105e-22 | 121 | 4.179e-21 | 12 | Genes in module_152 | www.broad.mit.e... |
Broad module_62 | View Gene Set | 9.903e-19 | 88 | 3.458e-17 | 13 | Genes in module_62 | www.broad.mit.e... |
Broad module_159 | View Gene Set | 4.154e-18 | 81 | 1.347e-16 | 14 | Genes in module_159 | www.broad.mit.e... |
Broad module_239 | View Gene Set | 5.067e-18 | 112 | 1.534e-16 | 15 | Genes in module_239 | www.broad.mit.e... |
Broad module_244 | View Gene Set | 1.745e-16 | 182 | 4.952e-15 | 16 | Genes in module_244 | www.broad.mit.e... |
Broad module_124 | View Gene Set | 2.944e-16 | 92 | 7.863e-15 | 17 | Genes in module_124 | www.broad.mit.e... |
Broad module_149 | View Gene Set | 1.007e-15 | 36 | 2.539e-14 | 18 | Genes in module_149 | www.broad.mit.e... |
Broad module_183 | View Gene Set | 1.259e-15 | 52 | 3.008e-14 | 19 | Genes in module_183 | www.broad.mit.e... |
Broad module_18 | View Gene Set | 1.35e-14 | 434 | 3.065e-13 | 20 | Genes in module_18 | www.broad.mit.e... |
Broad module_126 | View Gene Set | 2.734e-14 | 173 | 5.91e-13 | 21 | Genes in module_126 | www.broad.mit.e... |
Broad module_115 | View Gene Set | 1.704e-12 | 27 | 3.516e-11 | 22 | Genes in module_115 | www.broad.mit.e... |
Broad module_278 | View Gene Set | 1.168e-11 | 34 | 2.305e-10 | 23 | Genes in module_278 | www.broad.mit.e... |
Broad module_22 | View Gene Set | 2.134e-11 | 45 | 4.037e-10 | 24 | Genes in module_22 | www.broad.mit.e... |
Broad module_57 | View Gene Set | 3.441e-11 | 54 | 6.25e-10 | 25 | Genes in module_57 | www.broad.mit.e... |
Broad module_219 | View Gene Set | 8.472e-11 | 26 | 1.479e-09 | 26 | Genes in module_219 | www.broad.mit.e... |
Broad module_273 | View Gene Set | 1.018e-10 | 50 | 1.712e-09 | 27 | Genes in module_273 | www.broad.mit.e... |
Broad module_245 | View Gene Set | 1.106e-10 | 26 | 1.794e-09 | 28 | Genes in module_245 | www.broad.mit.e... |
Broad module_155 | View Gene Set | 3.51e-10 | 25 | 5.495e-09 | 29 | Genes in module_155 | www.broad.mit.e... |
Broad module_91 | View Gene Set | 1.4e-09 | 37 | 2.118e-08 | 30 | Genes in module_91 | www.broad.mit.e... |
Broad module_299 | View Gene Set | 1.623e-09 | 33 | 2.377e-08 | 31 | Genes in module_299 | www.broad.mit.e... |
Broad module_61 | View Gene Set | 1.774e-09 | 50 | 2.517e-08 | 32 | Genes in module_61 | www.broad.mit.e... |
Broad module_81 | View Gene Set | 2.462e-09 | 20 | 3.387e-08 | 33 | Genes in module_81 | www.broad.mit.e... |
Broad module_29 | View Gene Set | 4.093e-09 | 28 | 5.466e-08 | 34 | Genes in module_29 | www.broad.mit.e... |
Broad module_403 | View Gene Set | 4.374e-09 | 44 | 5.673e-08 | 35 | Genes in module_403 | www.broad.mit.e... |
Broad module_212 | View Gene Set | 5.362e-09 | 316 | 6.762e-08 | 36 | Genes in module_212 | www.broad.mit.e... |
Broad module_105 | View Gene Set | 6.52e-09 | 192 | 8.001e-08 | 37 | Genes in module_105 | www.broad.mit.e... |
Broad module_72 | View Gene Set | 9.937e-09 | 293 | 1.176e-07 | 38 | Genes in module_72 | www.broad.mit.e... |
Broad module_277 | View Gene Set | 1.01e-08 | 48 | 1.176e-07 | 38 | Genes in module_277 | www.broad.mit.e... |
Broad module_77 | View Gene Set | 2.074e-08 | 28 | 2.354e-07 | 40 | Genes in module_77 | www.broad.mit.e... |
Broad module_323 | View Gene Set | 2.553e-08 | 54 | 2.827e-07 | 41 | Genes in module_323 | www.broad.mit.e... |
Broad module_93 | View Gene Set | 4.749e-08 | 180 | 5.133e-07 | 42 | Genes in module_93 | www.broad.mit.e... |
Broad module_133 | View Gene Set | 6.863e-08 | 15 | 7.246e-07 | 43 | Genes in module_133 | www.broad.mit.e... |
Broad module_28 | View Gene Set | 7.597e-08 | 32 | 7.839e-07 | 44 | Genes in module_28 | www.broad.mit.e... |
Broad module_158 | View Gene Set | 7.977e-08 | 41 | 8.048e-07 | 45 | Genes in module_158 | www.broad.mit.e... |
Broad module_363 | View Gene Set | 1.04e-07 | 48 | 1.027e-06 | 46 | Genes in module_363 | www.broad.mit.e... |
Broad module_337 | View Gene Set | 1.15e-07 | 59 | 1.111e-06 | 47 | Genes in module_337 | www.broad.mit.e... |
Broad module_125 | View Gene Set | 1.282e-07 | 42 | 1.193e-06 | 48 | Genes in module_125 | www.broad.mit.e... |
Broad module_306 | View Gene Set | 1.287e-07 | 26 | 1.193e-06 | 48 | Genes in module_306 | www.broad.mit.e... |
Broad module_82 | View Gene Set | 1.71e-07 | 24 | 1.552e-06 | 50 | Genes in module_82 | www.broad.mit.e... |
Broad module_102 | View Gene Set | 3.065e-07 | 18 | 2.729e-06 | 51 | Genes in module_102 | www.broad.mit.e... |
Broad module_197 | View Gene Set | 3.355e-07 | 170 | 2.929e-06 | 52 | Genes in module_197 | www.broad.mit.e... |
Broad module_42 | View Gene Set | 6.808e-07 | 25 | 5.832e-06 | 53 | Genes in module_42 | www.broad.mit.e... |
Broad module_308 | View Gene Set | 7.366e-07 | 66 | 6.193e-06 | 54 | Genes in module_308 | www.broad.mit.e... |
Broad module_4 | View Gene Set | 7.591e-07 | 21 | 6.266e-06 | 55 | Genes in module_4 | www.broad.mit.e... |
Broad module_355 | View Gene Set | 8.703e-07 | 28 | 7.055e-06 | 56 | Genes in module_355 | www.broad.mit.e... |
Broad module_150 | View Gene Set | 1.265e-06 | 15 | 1.008e-05 | 57 | Genes in module_150 | www.broad.mit.e... |
Broad module_43 | View Gene Set | 2.156e-06 | 97 | 1.659e-05 | 58 | Genes in module_43 | www.broad.mit.e... |
Broad module_331 | View Gene Set | 2.127e-06 | 65 | 1.659e-05 | 58 | Genes in module_331 | www.broad.mit.e... |
Broad module_87 | View Gene Set | 2.403e-06 | 44 | 1.818e-05 | 60 | Genes in module_87 | www.broad.mit.e... |
Broad module_233 | View Gene Set | 2.631e-06 | 22 | 1.958e-05 | 61 | Genes in module_233 | www.broad.mit.e... |
Broad module_160 | View Gene Set | 3.086e-06 | 15 | 2.26e-05 | 62 | Genes in module_160 | www.broad.mit.e... |
Broad module_352 | View Gene Set | 3.327e-06 | 17 | 2.398e-05 | 63 | Genes in module_352 | www.broad.mit.e... |
Broad module_392 | View Gene Set | 5.093e-06 | 18 | 3.613e-05 | 64 | Genes in module_392 | www.broad.mit.e... |
Broad module_16 | View Gene Set | 5.423e-06 | 495 | 3.788e-05 | 65 | Genes in module_16 | www.broad.mit.e... |
Broad module_56 | View Gene Set | 7.716e-06 | 12 | 5.308e-05 | 66 | Genes in module_56 | www.broad.mit.e... |
Broad module_388 | View Gene Set | 7.973e-06 | 17 | 5.402e-05 | 67 | Genes in module_388 | www.broad.mit.e... |
Broad module_35 | View Gene Set | 8.39e-06 | 16 | 5.602e-05 | 68 | Genes in module_35 | www.broad.mit.e... |
Broad module_177 | View Gene Set | 1.07e-05 | 101 | 7.037e-05 | 69 | Genes in module_177 | www.broad.mit.e... |
Broad module_110 | View Gene Set | 1.208e-05 | 15 | 7.834e-05 | 70 | Genes in module_110 | www.broad.mit.e... |
Broad module_243 | View Gene Set | 1.382e-05 | 73 | 8.837e-05 | 71 | Genes in module_243 | www.broad.mit.e... |
Broad module_86 | View Gene Set | 1.464e-05 | 43 | 9.231e-05 | 72 | Genes in module_86 | www.broad.mit.e... |
Broad module_25 | View Gene Set | 1.591e-05 | 13 | 9.893e-05 | 73 | Genes in module_25 | www.broad.mit.e... |
Broad module_325 | View Gene Set | 1.861e-05 | 46 | 0.0001142 | 74 | Genes in module_325 | www.broad.mit.e... |
Broad module_15 | View Gene Set | 2.349e-05 | 347 | 0.0001422 | 75 | Genes in module_15 | www.broad.mit.e... |
Broad module_147 | View Gene Set | 2.749e-05 | 102 | 0.0001642 | 76 | Genes in module_147 | www.broad.mit.e... |
Broad module_21 | View Gene Set | 3.337e-05 | 10 | 0.0001968 | 77 | Genes in module_21 | www.broad.mit.e... |
Broad module_429 | View Gene Set | 3.605e-05 | 14 | 0.0002098 | 78 | Genes in module_429 | www.broad.mit.e... |
Broad module_303 | View Gene Set | 4.248e-05 | 27 | 0.0002441 | 79 | Genes in module_303 | www.broad.mit.e... |
Broad module_451 | View Gene Set | 4.546e-05 | 29 | 0.000258 | 80 | Genes in module_451 | www.broad.mit.e... |
Broad module_447 | View Gene Set | 6.169e-05 | 35 | 0.0003457 | 81 | Genes in module_447 | www.broad.mit.e... |
Broad module_307 | View Gene Set | 7.05e-05 | 24 | 0.0003903 | 82 | Genes in module_307 | www.broad.mit.e... |
Broad module_332 | View Gene Set | 0.0001195 | 35 | 0.0006534 | 83 | Genes in module_332 | www.broad.mit.e... |
Broad module_567 | View Gene Set | 0.0001439 | 90 | 0.0007775 | 84 | Genes in module_567 | www.broad.mit.e... |
Broad module_97 | View Gene Set | 0.0001647 | 91 | 0.0008799 | 85 | Genes in module_97 | www.broad.mit.e... |
Broad module_52 | View Gene Set | 0.0001894 | 415 | 0.0009997 | 86 | Genes in module_52 | www.broad.mit.e... |
Broad module_257 | View Gene Set | 0.0002527 | 137 | 0.001319 | 87 | Genes in module_257 | www.broad.mit.e... |
Broad module_206 | View Gene Set | 0.000258 | 139 | 0.001331 | 88 | Genes in module_206 | www.broad.mit.e... |
Broad module_116 | View Gene Set | 0.0002835 | 29 | 0.001446 | 89 | Genes in module_116 | www.broad.mit.e... |
Broad module_31 | View Gene Set | 0.0003414 | 7 | 0.001712 | 90 | Genes in module_31 | www.broad.mit.e... |
Broad module_503 | View Gene Set | 0.0003432 | 106 | 0.001712 | 90 | Genes in module_503 | www.broad.mit.e... |
Broad module_568 | View Gene Set | 0.00049 | 70 | 0.002418 | 92 | Genes in module_568 | www.broad.mit.e... |
Broad module_281 | View Gene Set | 0.000548 | 28 | 0.002675 | 93 | Genes in module_281 | www.broad.mit.e... |
Broad module_576 | View Gene Set | 0.0005954 | 104 | 0.002876 | 94 | Genes in module_576 | www.broad.mit.e... |
Broad module_50 | View Gene Set | 0.0006511 | 13 | 0.003112 | 95 | Genes in module_50 | www.broad.mit.e... |
Broad module_350 | View Gene Set | 0.0006722 | 57 | 0.003179 | 96 | Genes in module_350 | www.broad.mit.e... |
Broad module_195 | View Gene Set | 0.0008554 | 138 | 0.004003 | 97 | Genes in module_195 | www.broad.mit.e... |
Broad module_485 | View Gene Set | 0.0009679 | 44 | 0.004484 | 98 | Genes in module_485 | www.broad.mit.e... |
Broad module_182 | View Gene Set | 0.0009995 | 94 | 0.004584 | 99 | Genes in module_182 | www.broad.mit.e... |
Broad module_356 | View Gene Set | 0.00111 | 141 | 0.005041 | 100 | Genes in module_356 | www.broad.mit.e... |
Broad module_36 | View Gene Set | 0.001377 | 146 | 0.006129 | 101 | Genes in module_36 | www.broad.mit.e... |
Broad module_226 | View Gene Set | 0.001377 | 27 | 0.006129 | 101 | Genes in module_226 | www.broad.mit.e... |
Broad module_318 | View Gene Set | 0.001789 | 28 | 0.007883 | 103 | Genes in module_318 | www.broad.mit.e... |
Broad module_491 | View Gene Set | 0.001948 | 74 | 0.008505 | 104 | Genes in module_491 | www.broad.mit.e... |
Broad module_221 | View Gene Set | 0.002475 | 30 | 0.0107 | 105 | Genes in module_221 | www.broad.mit.e... |
Broad module_179 | View Gene Set | 0.002527 | 404 | 0.01082 | 106 | Genes in module_179 | www.broad.mit.e... |
Broad module_286 | View Gene Set | 0.003161 | 37 | 0.01341 | 107 | Genes in module_286 | www.broad.mit.e... |
Broad module_103 | View Gene Set | 0.003268 | 12 | 0.01374 | 108 | Genes in module_103 | www.broad.mit.e... |
Broad module_184 | View Gene Set | 0.004292 | 29 | 0.01788 | 109 | Genes in module_184 | www.broad.mit.e... |
Broad module_457 | View Gene Set | 0.004674 | 9 | 0.01929 | 110 | Genes in module_457 | www.broad.mit.e... |
Broad module_37 | View Gene Set | 0.004986 | 412 | 0.02039 | 111 | Genes in module_37 | www.broad.mit.e... |
Broad module_305 | View Gene Set | 0.005048 | 19 | 0.02046 | 112 | Genes in module_305 | www.broad.mit.e... |
Broad module_229 | View Gene Set | 0.005221 | 31 | 0.02098 | 113 | Genes in module_229 | www.broad.mit.e... |
Broad module_532 | View Gene Set | 0.006268 | 346 | 0.02496 | 114 | Genes in module_532 | www.broad.mit.e... |
Broad module_255 | View Gene Set | 0.007669 | 386 | 0.03027 | 115 | Genes in module_255 | www.broad.mit.e... |
Broad module_136 | View Gene Set | 0.008167 | 426 | 0.03197 | 116 | Genes in module_136 | www.broad.mit.e... |
Broad module_317 | View Gene Set | 0.008771 | 377 | 0.03403 | 117 | Genes in module_317 | www.broad.mit.e... |
Broad module_538 | View Gene Set | 0.01001 | 8 | 0.03851 | 118 | Genes in module_538 | www.broad.mit.e... |
Broad module_414 | View Gene Set | 0.01041 | 17 | 0.0397 | 119 | Genes in module_414 | www.broad.mit.e... |
Broad module_450 | View Gene Set | 0.01112 | 9 | 0.04208 | 120 | Genes in module_450 | www.broad.mit.e... |
Broad module_315 | View Gene Set | 0.01132 | 15 | 0.04247 | 121 | Genes in module_315 | www.broad.mit.e... |
Broad module_378 | View Gene Set | 0.01148 | 372 | 0.04261 | 122 | Genes in module_378 | www.broad.mit.e... |
Broad module_459 | View Gene Set | 0.01154 | 370 | 0.04261 | 122 | Genes in module_459 | www.broad.mit.e... |
Broad module_349 | View Gene Set | 0.01168 | 17 | 0.04276 | 124 | Genes in module_349 | www.broad.mit.e... |
Broad module_312 | View Gene Set | 0.01213 | 45 | 0.04404 | 125 | Genes in module_312 | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | View Gene Set | 2.102e-32 | 1197 | 1.734e-29 | 1 | Genes annotated by the GO term GO:0006139. The chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. | www.broad.mit.e... |
Broad BIOPOLYMER_METABOLIC_PROCESS | View Gene Set | 2.682e-31 | 1623 | 1.106e-28 | 2 | Genes annotated by the GO term GO:0043283. The chemical reactions and pathways involving biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. | www.broad.mit.e... |
Broad RNA_METABOLIC_PROCESS | View Gene Set | 1.584e-20 | 801 | 4.356e-18 | 3 | Genes annotated by the GO term GO:0016070. The chemical reactions and pathways involving RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. | www.broad.mit.e... |
Broad CELLULAR_PROTEIN_METABOLIC_PROCESS | View Gene Set | 1.179e-19 | 1085 | 2.431e-17 | 4 | Genes annotated by the GO term GO:0044267. The chemical reactions and pathways involving a specific protein rather than of proteins in general occurring at the level of an individual cell. Includes protein modification. | www.broad.mit.e... |
Broad PROTEIN_METABOLIC_PROCESS | View Gene Set | 1.881e-19 | 1198 | 3.104e-17 | 5 | Genes annotated by the GO term GO:0019538. The chemical reactions and pathways involving a specific protein rather than of proteins in general. Includes protein modification. | www.broad.mit.e... |
Broad RNA_PROCESSING | View Gene Set | 2.355e-19 | 147 | 3.239e-17 | 6 | Genes annotated by the GO term GO:0006396. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. | www.broad.mit.e... |
Broad CELLULAR_MACROMOLECULE_METABOLIC_PROCESS | View Gene Set | 3.145e-19 | 1099 | 3.706e-17 | 7 | Genes annotated by the GO term GO:0044260. The chemical reactions and pathways involving macromolecules large molecules including proteins nucleic acids and carbohydrates as carried out by individual cells. | www.broad.mit.e... |
Broad CELLULAR_BIOSYNTHETIC_PROCESS | View Gene Set | 6.446e-18 | 311 | 6.647e-16 | 8 | Genes annotated by the GO term GO:0044249. The chemical reactions and pathways resulting in the formation of substances carried out by individual cells. | www.broad.mit.e... |
Broad BIOSYNTHETIC_PROCESS | View Gene Set | 5.704e-17 | 459 | 5.229e-15 | 9 | Genes annotated by the GO term GO:0009058. The energy-requiring part of metabolism in which simpler substances are transformed into more complex ones as in growth and other biosynthetic processes. | www.broad.mit.e... |
Broad TRANSLATION | View Gene Set | 3.816e-16 | 177 | 3.149e-14 | 10 | Genes annotated by the GO term GO:0006412. The chemical reactions and pathways resulting in the formation of a protein. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. | www.broad.mit.e... |
Broad DNA_METABOLIC_PROCESS | View Gene Set | 1.515e-15 | 253 | 1.136e-13 | 11 | Genes annotated by the GO term GO:0006259. The chemical reactions and pathways involving DNA deoxyribonucleic acid one of the two main types of nucleic acid consisting of a long unbranched macromolecule formed from one or more commonly two strands of linked deoxyribonucleotides. | www.broad.mit.e... |
Broad RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY | View Gene Set | 3.913e-14 | 74 | 2.69e-12 | 12 | Genes annotated by the GO term GO:0022613. The cellular process by which a complex containing RNA and proteins is synthesized aggregates and bonds together. | www.broad.mit.e... |
Broad PROTEIN_FOLDING | View Gene Set | 7.97e-14 | 56 | 4.782e-12 | 13 | Genes annotated by the GO term GO:0006457. The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. | www.broad.mit.e... |
Broad MACROMOLECULE_BIOSYNTHETIC_PROCESS | View Gene Set | 8.115e-14 | 313 | 4.782e-12 | 13 | Genes annotated by the GO term GO:0009059. The chemical reactions and pathways resulting in the formation of macromolecules large molecules including proteins nucleic acids and carbohydrates. | www.broad.mit.e... |
Broad PROTEIN_RNA_COMPLEX_ASSEMBLY | View Gene Set | 1.116e-12 | 59 | 6.137e-11 | 15 | Genes annotated by the GO term GO:0022618. The aggregation arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. | www.broad.mit.e... |
Broad INTRACELLULAR_TRANSPORT | View Gene Set | 2.435e-12 | 271 | 1.256e-10 | 16 | Genes annotated by the GO term GO:0046907. The directed movement of substances within a cell. | www.broad.mit.e... |
Broad MACROMOLECULAR_COMPLEX_ASSEMBLY | View Gene Set | 2.002e-11 | 271 | 9.177e-10 | 17 | Genes annotated by the GO term GO:0065003. The aggregation arrangement and bonding together of a set of macromolecules to form a complex. | www.broad.mit.e... |
Broad CELL_CYCLE_GO_0007049 | View Gene Set | 1.957e-11 | 304 | 9.177e-10 | 17 | Genes annotated by the GO term GO:0007049. The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. | www.broad.mit.e... |
Broad CATABOLIC_PROCESS | View Gene Set | 1.623e-10 | 221 | 7.045e-09 | 19 | Genes annotated by the GO term GO:0009056. The chemical reactions and pathways resulting in the breakdown of substances including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. | www.broad.mit.e... |
Broad RNA_SPLICING | View Gene Set | 1.773e-10 | 73 | 7.312e-09 | 20 | Genes annotated by the GO term GO:0008380. The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. | www.broad.mit.e... |
Broad CELL_CYCLE_PROCESS | View Gene Set | 4.137e-10 | 187 | 1.625e-08 | 21 | Genes annotated by the GO term GO:0022402. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. | www.broad.mit.e... |
Broad CELLULAR_COMPONENT_ASSEMBLY | View Gene Set | 4.634e-10 | 288 | 1.738e-08 | 22 | Genes annotated by the GO term GO:0022607. A cellular process that results in the assembly of a part of the cell. | www.broad.mit.e... |
Broad CELLULAR_CATABOLIC_PROCESS | View Gene Set | 7.1e-10 | 209 | 2.547e-08 | 23 | Genes annotated by the GO term GO:0044248. The chemical reactions and pathways resulting in the breakdown of substances carried out by individual cells. | www.broad.mit.e... |
Broad INTRACELLULAR_PROTEIN_TRANSPORT | View Gene Set | 1.479e-09 | 138 | 5.085e-08 | 24 | Genes annotated by the GO term GO:0006886. The directed movement of proteins in a cell including the movement of proteins between specific compartments or structures within a cell such as organelles of a eukaryotic cell. | www.broad.mit.e... |
Broad DNA_REPLICATION | View Gene Set | 1.721e-09 | 101 | 5.678e-08 | 25 | Genes annotated by the GO term GO:0006260. The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. | www.broad.mit.e... |
Broad ESTABLISHMENT_OF_CELLULAR_LOCALIZATION | View Gene Set | 2.049e-09 | 342 | 6.503e-08 | 26 | Genes annotated by the GO term GO:0051649. The directed movement of a substance or cellular entity such as a protein complex or organelle to a specific location within or in the membrane of a cell. | www.broad.mit.e... |
Broad TRANSLATIONAL_INITIATION | View Gene Set | 2.238e-09 | 39 | 6.838e-08 | 27 | Genes annotated by the GO term GO:0006413. The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome mRNA and an initiation complex that contains the first aminoacyl-tRNA. | www.broad.mit.e... |
Broad PROTEIN_TRANSPORT | View Gene Set | 3.763e-09 | 150 | 1.109e-07 | 28 | Genes annotated by the GO term GO:0015031. The directed movement of proteins into out of within or between cells. | www.broad.mit.e... |
Broad MITOTIC_CELL_CYCLE | View Gene Set | 6.73e-09 | 148 | 1.914e-07 | 29 | Genes annotated by the GO term GO:0000278. Progression through the phases of the mitotic cell cycle the most common eukaryotic cell cycle which canonically comprises four successive phases called G1 S G2 and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division or G1 and G2 phases may be absent. | www.broad.mit.e... |
Broad RESPONSE_TO_DNA_DAMAGE_STIMULUS | View Gene Set | 7.15e-09 | 159 | 1.966e-07 | 30 | Genes annotated by the GO term GO:0006974. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. | www.broad.mit.e... |
Broad CELLULAR_LOCALIZATION | View Gene Set | 7.599e-09 | 360 | 2.014e-07 | 31 | Genes annotated by the GO term GO:0051641. The processes by which a substance or cellular entity such as a protein complex or organelle is transported to and/or maintained in a specific location within or in the membrane of a cell. | www.broad.mit.e... |
Broad MRNA_METABOLIC_PROCESS | View Gene Set | 7.811e-09 | 70 | 2.014e-07 | 31 | Genes annotated by the GO term GO:0016071. The chemical reactions and pathways involving mRNA messenger RNA which is responsible for carrying the coded genetic 'message' transcribed from DNA to sites of protein assembly at the ribosomes. | www.broad.mit.e... |
Broad CHROMOSOME_ORGANIZATION_AND_BIOGENESIS | View Gene Set | 1.198e-08 | 117 | 2.994e-07 | 33 | Genes annotated by the GO term GO:0051276. A process that is carried out at the cellular level that results in the formation arrangement of constituent parts or disassembly of chromosomes structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. | www.broad.mit.e... |
Broad ORGANELLE_ORGANIZATION_AND_BIOGENESIS | View Gene Set | 1.288e-08 | 458 | 3.125e-07 | 34 | Genes annotated by the GO term GO:0006996. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of any organelle within a cell. | www.broad.mit.e... |
Broad MACROMOLECULE_LOCALIZATION | View Gene Set | 1.947e-08 | 228 | 4.59e-07 | 35 | Genes annotated by the GO term GO:0033036. The processes by which a macromolecule is transported to or maintained in a specific location. | www.broad.mit.e... |
Broad MRNA_PROCESSING_GO_0006397 | View Gene Set | 3.344e-08 | 59 | 7.664e-07 | 36 | Genes annotated by the GO term GO:0006397. Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. | www.broad.mit.e... |
Broad RESPONSE_TO_ENDOGENOUS_STIMULUS | View Gene Set | 3.662e-08 | 197 | 8.164e-07 | 37 | Genes annotated by the GO term GO:0009719. A change in state or activity of a cell or an organism (in terms of movement secretion enzyme production gene expression etc.) as a result of an endogenous stimulus. | www.broad.mit.e... |
Broad CELL_CYCLE_PHASE | View Gene Set | 3.771e-08 | 167 | 8.186e-07 | 38 | Genes annotated by the GO term GO:0022403. A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. | www.broad.mit.e... |
Broad TRANSCRIPTION_DNA_DEPENDENT | View Gene Set | 4.022e-08 | 623 | 8.295e-07 | 39 | Genes annotated by the GO term GO:0006351. The synthesis of RNA on a template of DNA. | www.broad.mit.e... |
Broad RNA_BIOSYNTHETIC_PROCESS | View Gene Set | 3.924e-08 | 625 | 8.295e-07 | 39 | Genes annotated by the GO term GO:0032774. The chemical reactions and pathways resulting in the formation of RNA ribonucleic acid one of the two main type of nucleic acid consisting of a long unbranched macromolecule formed from ribonucleotides joined in 3' 5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. | www.broad.mit.e... |
Broad MACROMOLECULE_CATABOLIC_PROCESS | View Gene Set | 5.347e-08 | 135 | 1.076e-06 | 41 | Genes annotated by the GO term GO:0009057. The chemical reactions and pathways resulting in the breakdown of a macromolecule any large molecule including proteins nucleic acids and carbohydrates. | www.broad.mit.e... |
Broad BIOPOLYMER_CATABOLIC_PROCESS | View Gene Set | 6.922e-08 | 115 | 1.36e-06 | 42 | Genes annotated by the GO term GO:0043285. The chemical reactions and pathways resulting in the breakdown of biopolymers long repeating chains of monomers found in nature e.g. polysaccharides and proteins. | www.broad.mit.e... |
Broad TRANSCRIPTION | View Gene Set | 8.178e-08 | 738 | 1.569e-06 | 43 | Genes annotated by the GO term GO:0006350. The synthesis of either RNA on a template of DNA or DNA on a template of RNA. | www.broad.mit.e... |
Broad DNA_REPAIR | View Gene Set | 1.209e-07 | 123 | 2.267e-06 | 44 | Genes annotated by the GO term GO:0006281. The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations chemical mutagens fungal and bacterial toxins etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal base excision repair nucleotide excision repair photoreactivation bypass double-strand break repair pathway and mismatch repair pathway. | www.broad.mit.e... |
Broad PROTEIN_LOCALIZATION | View Gene Set | 1.462e-07 | 207 | 2.68e-06 | 45 | Genes annotated by the GO term GO:0008104. The processes by which a protein is transported to or maintained in a specific location. | www.broad.mit.e... |
Broad REGULATION_OF_TRANSLATIONAL_INITIATION | View Gene Set | 2.452e-07 | 31 | 4.398e-06 | 46 | Genes annotated by the GO term GO:0006446. Any process that modulates the frequency rate or extent of translational initiation. | www.broad.mit.e... |
Broad MITOCHONDRION_ORGANIZATION_AND_BIOGENESIS | View Gene Set | 3.614e-07 | 47 | 6.297e-06 | 47 | Genes annotated by the GO term GO:0007005. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of a mitochondrion; includes mitochondrial morphology and distribution and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. | www.broad.mit.e... |
Broad CELLULAR_MACROMOLECULE_CATABOLIC_PROCESS | View Gene Set | 3.664e-07 | 103 | 6.297e-06 | 47 | Genes annotated by the GO term GO:0044265. The chemical reactions and pathways resulting in the breakdown of a macromolecule any large molecule including proteins nucleic acids and carbohydrates as carried out by individual cells. | www.broad.mit.e... |
Broad REGULATION_OF_CELLULAR_METABOLIC_PROCESS | View Gene Set | 4.176e-07 | 767 | 7.03e-06 | 49 | Genes annotated by the GO term GO:0031323. Any process that modulates the frequency rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. | www.broad.mit.e... |
Broad REGULATION_OF_METABOLIC_PROCESS | View Gene Set | 4.765e-07 | 779 | 7.708e-06 | 50 | Genes annotated by the GO term GO:0019222. Any process that modulates the frequency rate or extent of the chemical reactions and pathways within a cell or an organism. | www.broad.mit.e... |
Broad M_PHASE_OF_MITOTIC_CELL_CYCLE | View Gene Set | 4.698e-07 | 83 | 7.708e-06 | 50 | Genes annotated by the GO term GO:0000087. Progression through M phase the part of the mitotic cell cycle during which mitosis takes place. | www.broad.mit.e... |
Broad ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | View Gene Set | 5.215e-07 | 183 | 8.273e-06 | 52 | Genes annotated by the GO term GO:0045184. The directed movement of a protein to a specific location. | www.broad.mit.e... |
Broad PROTEIN_CATABOLIC_PROCESS | View Gene Set | 5.499e-07 | 68 | 8.56e-06 | 53 | Genes annotated by the GO term GO:0030163. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native active configuration with or without the hydrolysis of peptide bonds. | www.broad.mit.e... |
Broad CELLULAR_PROTEIN_CATABOLIC_PROCESS | View Gene Set | 9.849e-07 | 58 | 1.505e-05 | 54 | Genes annotated by the GO term GO:0044257. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. | www.broad.mit.e... |
Broad TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | View Gene Set | 1.708e-06 | 449 | 2.563e-05 | 55 | Genes annotated by the GO term GO:0006366. The synthesis of RNA from a DNA template by RNA polymerase II (Pol II) originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). | www.broad.mit.e... |
Broad MITOSIS | View Gene Set | 1.763e-06 | 81 | 2.597e-05 | 56 | Genes annotated by the GO term GO:0007067. Progression through mitosis the division of the eukaryotic cell nucleus to produce two daughter nuclei that usually contain the identical chromosome complement to their mother. | www.broad.mit.e... |
Broad PROTEIN_TARGETING | View Gene Set | 2.854e-06 | 103 | 4.13e-05 | 57 | Genes annotated by the GO term GO:0006605. The process of targeting specific proteins to particular membrane-bound subcellular organelles. Usually requires an organelle specific protein sequence motif. | www.broad.mit.e... |
Broad ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CHROMATIN_ARCHITECTURE | View Gene Set | 3.142e-06 | 72 | 4.47e-05 | 58 | Genes annotated by the GO term GO:0006325. The specification formation and maintenance of the physical structure of eukaryotic chromatin. | www.broad.mit.e... |
Broad REGULATION_OF_GENE_EXPRESSION | View Gene Set | 6.867e-06 | 660 | 9.602e-05 | 59 | Genes annotated by the GO term GO:0010468. Any process that modulates the frequency rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. | www.broad.mit.e... |
Broad REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | View Gene Set | 9.349e-06 | 601 | 0.0001286 | 60 | Genes annotated by the GO term GO:0019219. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. | www.broad.mit.e... |
Broad M_PHASE | View Gene Set | 9.547e-06 | 111 | 0.0001291 | 61 | Genes annotated by the GO term GO:0000279. Progression through M phase the part of the cell cycle comprising nuclear division. | www.broad.mit.e... |
Broad BIOPOLYMER_MODIFICATION | View Gene Set | 1.071e-05 | 627 | 0.0001426 | 62 | Genes annotated by the GO term GO:0043412. The covalent alteration of one or more monomeric units in a polypeptide polynucleotide polysaccharide or other biological polymer resulting in a change in its properties. | www.broad.mit.e... |
Broad DNA_DEPENDENT_DNA_REPLICATION | View Gene Set | 1.287e-05 | 55 | 0.0001685 | 63 | Genes annotated by the GO term GO:0006261. The process whereby new strands of DNA are synthesized using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. | www.broad.mit.e... |
Broad CHROMOSOME_SEGREGATION | View Gene Set | 2.113e-05 | 31 | 0.0002724 | 64 | Genes annotated by the GO term GO:0007059. The process by which genetic material in the form of chromosomes is organized and then physically separated and apportioned to two or more sets. | www.broad.mit.e... |
Broad MITOCHONDRIAL_TRANSPORT | View Gene Set | 2.321e-05 | 20 | 0.0002946 | 65 | Genes annotated by the GO term GO:0006839. Transport of substances into out of or within a mitochondrion. | www.broad.mit.e... |
Broad CHROMATIN_MODIFICATION | View Gene Set | 3.711e-05 | 50 | 0.0004638 | 66 | Genes annotated by the GO term GO:0016568. The alteration of DNA or protein in chromatin which may result in changing the chromatin structure. | www.broad.mit.e... |
Broad UBIQUITIN_CYCLE | View Gene Set | 3.859e-05 | 48 | 0.0004752 | 67 | Genes annotated by the GO term GO:0006512. The cyclical process by which one or more ubiquitin moieties are added to (ubiquitination) and removed from (deubiquitination) a protein. | www.broad.mit.e... |
Broad NUCLEOBASENUCLEOSIDE_AND_NUCLEOTIDE_METABOLIC_PROCESS | View Gene Set | 4.459e-05 | 50 | 0.000541 | 68 | Genes annotated by the GO term GO:0055086. The chemical reactions and pathways involving nucleobases nucleosides and nucleotides. | www.broad.mit.e... |
Broad PROTEIN_MODIFICATION_PROCESS | View Gene Set | 4.735e-05 | 610 | 0.0005661 | 69 | Genes annotated by the GO term GO:0006464. The covalent alteration of one or more amino acids occurring in proteins peptides and nascent polypeptides (co-translational post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | View Gene Set | 5.581e-05 | 205 | 0.0006578 | 70 | Genes annotated by the GO term GO:0045934. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways involving nucleobases nucleosides nucleotides and nucleic acids. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_CELLULAR_PROCESS | View Gene Set | 6.478e-05 | 629 | 0.0007528 | 71 | Genes annotated by the GO term GO:0048523. Any process that stops prevents or reduces the frequency rate or extent of cellular processes those that are carried out at the cellular level but are not necessarily restricted to a single cell. For example cell communication occurs among more than one cell but occurs at the cellular level. | www.broad.mit.e... |
Broad PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION | View Gene Set | 6.745e-05 | 43 | 0.0007728 | 72 | Genes annotated by the GO term GO:0032446. A process by which one or more moieties of a small protein such as ubiquitin or a ubiquitin-like protein are covalently attached to a target protein. | www.broad.mit.e... |
Broad AMINO_ACID_METABOLIC_PROCESS | View Gene Set | 8.167e-05 | 75 | 0.0009229 | 73 | Genes annotated by the GO term GO:0006520. The chemical reactions and pathways involving amino acids organic acids containing one or more amino substituents. | www.broad.mit.e... |
Broad PROTEIN_TARGETING_TO_MITOCHONDRION | View Gene Set | 8.337e-05 | 10 | 0.0009295 | 74 | Genes annotated by the GO term GO:0006626. The process of directing proteins towards and into the mitochondrion mediated by mitochondrial proteins that recognize signals contained within the imported protein. | www.broad.mit.e... |
Broad PROTEIN_UBIQUITINATION | View Gene Set | 9.569e-05 | 40 | 0.001053 | 75 | Genes annotated by the GO term GO:0016567. The process by which one or more ubiquitin moieties are added to a protein. | www.broad.mit.e... |
Broad NUCLEAR_TRANSPORT | View Gene Set | 0.0001078 | 84 | 0.001171 | 76 | Genes annotated by the GO term GO:0051169. The directed movement of substances into out of or within the nucleus. | www.broad.mit.e... |
Broad RIBOSOME_BIOGENESIS_AND_ASSEMBLY | View Gene Set | 0.0001199 | 14 | 0.001285 | 77 | Genes annotated by the GO term GO:0042254. The process of the formation of the constituents of the ribosome subunits their assembly and their transport to the sites of protein synthesis. | www.broad.mit.e... |
Broad TRNA_METABOLIC_PROCESS | View Gene Set | 0.0001318 | 18 | 0.001394 | 78 | Genes annotated by the GO term GO:0006399. The chemical reactions and pathways involving tRNA transfer RNA a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases the function of which has not been completely established. | www.broad.mit.e... |
Broad INTERPHASE | View Gene Set | 0.0001448 | 68 | 0.001512 | 79 | Genes annotated by the GO term GO:0051325. Progression through interphase the stage of cell cycle between successive rounds of chromosome segregation. Canonically interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs. | www.broad.mit.e... |
Broad ORGANIC_ACID_METABOLIC_PROCESS | View Gene Set | 0.0001513 | 175 | 0.001522 | 80 | Genes annotated by the GO term GO:0006082. The chemical reactions and pathways involving organic acids any acidic compound containing carbon in covalent linkage. | www.broad.mit.e... |
Broad CELL_CYCLE_CHECKPOINT_GO_0000075 | View Gene Set | 0.000149 | 47 | 0.001522 | 80 | Genes annotated by the GO term GO:0000075. A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. | www.broad.mit.e... |
Broad REGULATION_OF_RNA_METABOLIC_PROCESS | View Gene Set | 0.0001502 | 457 | 0.001522 | 80 | Genes annotated by the GO term GO:0051252. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving RNA. | www.broad.mit.e... |
Broad RNA_SPLICINGVIA_TRANSESTERIFICATION_REACTIONS | View Gene Set | 0.000154 | 27 | 0.001531 | 83 | Genes annotated by the GO term GO:0000375. Splicing of RNA via a series of two transesterification reactions. | www.broad.mit.e... |
Broad NUCLEOCYTOPLASMIC_TRANSPORT | View Gene Set | 0.0001877 | 83 | 0.001844 | 84 | Genes annotated by the GO term GO:0006913. The directed movement of molecules between the nucleus and the cytoplasm. | www.broad.mit.e... |
Broad PROTEIN_COMPLEX_ASSEMBLY | View Gene Set | 0.0002286 | 167 | 0.002219 | 85 | Genes annotated by the GO term GO:0006461. The aggregation arrangement and bonding together of a set of components to form a protein complex. | www.broad.mit.e... |
Broad REGULATION_OF_DNA_METABOLIC_PROCESS | View Gene Set | 0.0002477 | 44 | 0.002376 | 86 | Genes annotated by the GO term GO:0051052. Any process that modulates the frequency rate or extent of the chemical reactions and pathways involving DNA. | www.broad.mit.e... |
Broad APOPTOSIS_GO | View Gene Set | 0.0002595 | 423 | 0.002461 | 87 | Genes annotated by the GO term GO:0006915. A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. | www.broad.mit.e... |
Broad CARBOXYLIC_ACID_METABOLIC_PROCESS | View Gene Set | 0.0002639 | 173 | 0.002474 | 88 | Genes annotated by the GO term GO:0019752. The chemical reactions and pathways involving carboxylic acids any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). | www.broad.mit.e... |
Broad CELLULAR_PROTEIN_COMPLEX_ASSEMBLY | View Gene Set | 0.0002829 | 33 | 0.002605 | 89 | Genes annotated by the GO term GO:0043623. The aggregation arrangement and bonding together of a set of components to form a protein complex occurring at the level of an individual cell. | www.broad.mit.e... |
Broad INTERPHASE_OF_MITOTIC_CELL_CYCLE | View Gene Set | 0.0002842 | 62 | 0.002605 | 89 | Genes annotated by the GO term GO:0051329. Progression through interphase the stage of cell cycle between successive rounds of mitosis. Canonically interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs. | www.broad.mit.e... |
Broad RRNA_PROCESSING | View Gene Set | 0.0002952 | 11 | 0.002676 | 91 | Genes annotated by the GO term GO:0006364. Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. | www.broad.mit.e... |
Broad PROGRAMMED_CELL_DEATH | View Gene Set | 0.0003353 | 424 | 0.003004 | 92 | Genes annotated by the GO term GO:0012501. Cell death resulting from activation of endogenous cellular processes. | www.broad.mit.e... |
Broad REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT | View Gene Set | 0.0003387 | 452 | 0.003004 | 92 | Genes annotated by the GO term GO:0006355. Any process that modulates the frequency rate or extent of DNA-dependent transcription. | www.broad.mit.e... |
Broad REGULATION_OF_TRANSCRIPTION | View Gene Set | 0.0003485 | 555 | 0.003059 | 94 | Genes annotated by the GO term GO:0045449. Any process that modulates the frequency rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_APOPTOSIS | View Gene Set | 0.0003854 | 147 | 0.003347 | 95 | Genes annotated by the GO term GO:0043066. Any process that stops prevents or reduces the frequency rate or extent of cell death by apoptosis. | www.broad.mit.e... |
Broad REGULATION_OF_CELL_CYCLE | View Gene Set | 0.0003923 | 176 | 0.003372 | 96 | Genes annotated by the GO term GO:0051726. Any process that modulates the rate or extent of progression through the cell cycle. | www.broad.mit.e... |
Broad PROTEIN_EXPORT_FROM_NUCLEUS | View Gene Set | 0.0004176 | 10 | 0.003552 | 97 | Genes annotated by the GO term GO:0006611. The directed movement of a protein from the nucleus into the cytoplasm. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS | View Gene Set | 0.000448 | 252 | 0.003771 | 98 | Genes annotated by the GO term GO:0031324. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. | www.broad.mit.e... |
Broad COFACTOR_METABOLIC_PROCESS | View Gene Set | 0.0004599 | 53 | 0.003833 | 99 | Genes annotated by the GO term GO:0051186. The chemical reactions and pathways involving a cofactor a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic such as the metal atoms zinc iron and copper in certain forms or organic in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. | www.broad.mit.e... |
Broad DOUBLE_STRAND_BREAK_REPAIR | View Gene Set | 0.0004872 | 22 | 0.00398 | 100 | Genes annotated by the GO term GO:0006302. The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. | www.broad.mit.e... |
Broad REGULATION_OF_APOPTOSIS | View Gene Set | 0.0004848 | 335 | 0.00398 | 100 | Genes annotated by the GO term GO:0042981. Any process that modulates the occurrence or rate of cell death by apoptosis. | www.broad.mit.e... |
Broad POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | View Gene Set | 0.0005188 | 80 | 0.004196 | 102 | Genes annotated by the GO term GO:0043123. Any process that activates or increases the frequency rate or extent of an I-kappaB kinase/NF-kappaB induced cascade. | www.broad.mit.e... |
Broad ANTI_APOPTOSIS | View Gene Set | 0.0005601 | 115 | 0.004486 | 103 | Genes annotated by the GO term GO:0006916. A process which directly inhibits any of the steps required for cell death by apoptosis. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_METABOLIC_PROCESS | View Gene Set | 0.0005965 | 255 | 0.004687 | 104 | Genes annotated by the GO term GO:0009892. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways within a cell or an organism. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_PROGRAMMED_CELL_DEATH | View Gene Set | 0.0005939 | 148 | 0.004687 | 104 | Genes annotated by the GO term GO:0043069. Any process that stops prevents or reduces the frequency rate or extent of programmed cell death cell death resulting from activation of endogenous cellular processes. | www.broad.mit.e... |
Broad REGULATION_OF_PROGRAMMED_CELL_DEATH | View Gene Set | 0.0006386 | 336 | 0.00497 | 106 | Genes annotated by the GO term GO:0043067. Any process that modulates the frequency rate or extent of programmed cell death cell death resulting from activation of endogenous cellular processes. | www.broad.mit.e... |
Broad RRNA_METABOLIC_PROCESS | View Gene Set | 0.000664 | 12 | 0.00512 | 107 | Genes annotated by the GO term GO:0016072. The chemical reactions and pathways involving rRNA ribosomal RNA a structural constituent of ribosomes. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_TRANSCRIPTION | View Gene Set | 0.0006712 | 185 | 0.005128 | 108 | Genes annotated by the GO term GO:0016481. Any process that stops prevents or reduces the frequency rate or extent of transcription. | www.broad.mit.e... |
Broad ONE_CARBON_COMPOUND_METABOLIC_PROCESS | View Gene Set | 0.0007398 | 26 | 0.005599 | 109 | Genes annotated by the GO term GO:0006730. The chemical reactions and pathways involving compounds containing a single carbon atom. | www.broad.mit.e... |
Broad REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | View Gene Set | 0.0007701 | 30 | 0.005776 | 110 | Genes annotated by the GO term GO:0040029. Any process that modulates the frequency rate or extent of gene expression; the process is mitotically or meiotically heritable or is stably self-propagated in the cytoplasm of a resting cell and does not entail a change in DNA sequence. | www.broad.mit.e... |
Broad NITROGEN_COMPOUND_METABOLIC_PROCESS | View Gene Set | 0.000788 | 150 | 0.005857 | 111 | Genes annotated by the GO term GO:0006807. The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation nitrification denitrification assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium. | www.broad.mit.e... |
Broad GOLGI_VESICLE_TRANSPORT | View Gene Set | 0.0008217 | 47 | 0.006053 | 112 | Genes annotated by the GO term GO:0048193. The directed movement of substances into out of or within the Golgi apparatus mediated by vesicles. | www.broad.mit.e... |
Broad CHROMOSOME_CONDENSATION | View Gene Set | 0.0008372 | 10 | 0.006112 | 113 | Genes annotated by the GO term GO:0030261. The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division or during apoptosis in eukaryotic cells. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS | View Gene Set | 0.0008703 | 659 | 0.006298 | 114 | Genes annotated by the GO term GO:0048519. Any process that stops prevents or reduces the frequency rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression protein modification or interaction with a protein or substrate molecule. | www.broad.mit.e... |
Broad CHROMATIN_ASSEMBLY_OR_DISASSEMBLY | View Gene Set | 0.0009869 | 26 | 0.00708 | 115 | Genes annotated by the GO term GO:0006333. The formation or destruction of chromatin structures. | www.broad.mit.e... |
Broad REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | View Gene Set | 0.001167 | 285 | 0.008302 | 116 | Genes annotated by the GO term GO:0006357. Any process that modulates the frequency rate or extent of transcription from an RNA polymerase II promoter. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_DNA_METABOLIC_PROCESS | View Gene Set | 0.001253 | 17 | 0.008839 | 117 | Genes annotated by the GO term GO:0051053. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways involving DNA. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_TRANSCRIPTION_DNA_DEPENDENT | View Gene Set | 0.001288 | 127 | 0.008927 | 118 | Genes annotated by the GO term GO:0045892. Any process that stops prevents or reduces the frequency rate or extent of DNA-dependent transcription. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | View Gene Set | 0.001288 | 127 | 0.008927 | 118 | Genes annotated by the GO term GO:0051253. Any process that stops prevents or reduces the frequency rate or extent of the chemical reactions and pathways involving RNA. | www.broad.mit.e... |
Broad DNA_RECOMBINATION | View Gene Set | 0.001414 | 47 | 0.009721 | 120 | Genes annotated by the GO term GO:0006310. The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment intrachromosomal recombination or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation conjugation transduction or F-duction. | www.broad.mit.e... |
Broad PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS | View Gene Set | 0.001457 | 9 | 0.009934 | 121 | Genes annotated by the GO term GO:0006220. The chemical reactions and pathways involving a pyrimidine nucleotide a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. | www.broad.mit.e... |
Broad SISTER_CHROMATID_SEGREGATION | View Gene Set | 0.001608 | 17 | 0.01087 | 122 | Genes annotated by the GO term GO:0000819. The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets. | www.broad.mit.e... |
Broad CHROMATIN_REMODELING | View Gene Set | 0.001744 | 23 | 0.0117 | 123 | Genes annotated by the GO term GO:0006338. Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. | www.broad.mit.e... |
Broad MITOTIC_SISTER_CHROMATID_SEGREGATION | View Gene Set | 0.001778 | 16 | 0.01183 | 124 | Genes annotated by the GO term GO:0000070. The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome composed of two sister chromatids aligns at the cell equator paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. | www.broad.mit.e... |
Broad AMINO_ACID_AND_DERIVATIVE_METABOLIC_PROCESS | View Gene Set | 0.001881 | 98 | 0.01241 | 125 | Genes annotated by the GO term GO:0006519. The chemical reactions and pathways involving amino acids organic acids containing one or more amino substituents and compounds derived from amino acids. | www.broad.mit.e... |
Broad ER_NUCLEAR_SIGNALING_PATHWAY | View Gene Set | 0.002147 | 16 | 0.01405 | 126 | Genes annotated by the GO term GO:0006984. Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus usually resulting in a change in transcriptional regulation. | www.broad.mit.e... |
Broad ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | View Gene Set | 0.002383 | 17 | 0.01548 | 127 | Genes annotated by the GO term GO:0051656. The directed movement of an organelle to a specific location. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_DNA_REPLICATION | View Gene Set | 0.002409 | 12 | 0.01553 | 128 | Genes annotated by the GO term GO:0008156. Any process that stops prevents or reduces the frequency rate or extent of DNA replication. | www.broad.mit.e... |
Broad NITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | View Gene Set | 0.002575 | 25 | 0.01647 | 129 | Genes annotated by the GO term GO:0044271. The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. | www.broad.mit.e... |
Broad UNFOLDED_PROTEIN_RESPONSE | View Gene Set | 0.002698 | 10 | 0.01712 | 130 | Genes annotated by the GO term GO:0030968. The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation. | www.broad.mit.e... |
Broad G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE | View Gene Set | 0.002757 | 27 | 0.01736 | 131 | Genes annotated by the GO term GO:0000082. Progression from G1 phase to S phase of the mitotic cell cycle. | www.broad.mit.e... |
Broad COENZYME_METABOLIC_PROCESS | View Gene Set | 0.002976 | 37 | 0.0186 | 132 | Genes annotated by the GO term GO:0006732. The chemical reactions and pathways involving coenzymes any of various nonprotein organic cofactors that are required in addition to an enzyme and a substrate for an enzymatic reaction to proceed. | www.broad.mit.e... |
Broad NUCLEOTIDE_METABOLIC_PROCESS | View Gene Set | 0.003422 | 40 | 0.02123 | 133 | Genes annotated by the GO term GO:0009117. The chemical reactions and pathways involving a nucleotide a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono- di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). | www.broad.mit.e... |
Broad NUCLEOTIDE_SUGAR_METABOLIC_PROCESS | View Gene Set | 0.003624 | 9 | 0.02231 | 134 | Genes annotated by the GO term GO:0009225. The chemical reactions and pathways involving nucleotide-sugars any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. | www.broad.mit.e... |
Broad AEROBIC_RESPIRATION | View Gene Set | 0.003851 | 15 | 0.02353 | 135 | Genes annotated by the GO term GO:0009060. The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor. | www.broad.mit.e... |
Broad VIRAL_GENOME_REPLICATION | View Gene Set | 0.004265 | 21 | 0.02581 | 136 | Genes annotated by the GO term GO:0019079. Any process involved directly in viral genome replication including viral nucleotide metabolism. | www.broad.mit.e... |
Broad NUCLEAR_EXPORT | View Gene Set | 0.004286 | 31 | 0.02581 | 136 | Genes annotated by the GO term GO:0051168. The directed movement of substances out of the nucleus. | www.broad.mit.e... |
Broad I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | View Gene Set | 0.004323 | 107 | 0.02584 | 138 | Genes annotated by the GO term GO:0007249. A series of reactions initiated by the activation of the transcription factor NF-kappaB. NF-kappaB is sequestered by the inhibitor I-kappaB and is released when I-kappaB is phosphorylated by activated I-kappaB kinase. | www.broad.mit.e... |
Broad AGING | View Gene Set | 0.004451 | 12 | 0.02642 | 139 | Genes annotated by the GO term GO:0007568. The inherent decline over time from the optimal fertility and viability of early maturity that may precede death and may be preceded by other indications such as sterility. | www.broad.mit.e... |
Broad DNA_REPLICATION_INITIATION | View Gene Set | 0.005007 | 15 | 0.0295 | 140 | Genes annotated by the GO term GO:0006270. The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix the recruitment of DNA polymerases and the initiation of polymerase action. | www.broad.mit.e... |
Broad POST_TRANSLATIONAL_PROTEIN_MODIFICATION | View Gene Set | 0.005127 | 462 | 0.03 | 141 | Genes annotated by the GO term GO:0043687. The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome. | www.broad.mit.e... |
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_TRANSPORT | View Gene Set | 0.005246 | 31 | 0.03048 | 142 | Genes annotated by the GO term GO:0015931. The directed movement of nucleobases nucleosides nucleotides and nucleic acids into out of within or between cells. | www.broad.mit.e... |
Broad LIPID_BIOSYNTHETIC_PROCESS | View Gene Set | 0.00529 | 97 | 0.03052 | 143 | Genes annotated by the GO term GO:0008610. The chemical reactions and pathways resulting in the formation of lipids compounds soluble in an organic solvent but not or sparingly in an aqueous solvent. | www.broad.mit.e... |
Broad PROTEOLYSIS | View Gene Set | 0.005635 | 187 | 0.03228 | 144 | Genes annotated by the GO term GO:0006508. The hydrolysis of a peptide bond or bonds within a protein. | www.broad.mit.e... |
Broad VESICLE_MEDIATED_TRANSPORT | View Gene Set | 0.005884 | 188 | 0.03348 | 145 | Genes annotated by the GO term GO:0016192. The directed movement of substances either within a vesicle or in the vesicle membrane into out of or within a cell. | www.broad.mit.e... |
Broad MITOCHONDRIAL_MEMBRANE_ORGANIZATION_AND_BIOGENESIS | View Gene Set | 0.005945 | 11 | 0.03359 | 146 | Genes annotated by the GO term GO:0007006. A process that is carried out at the cellular level which results in the formation arrangement of constituent parts or disassembly of the mitochondrial membrane the lipid bilayer surrounding a mitochondrion. | www.broad.mit.e... |
Broad REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | View Gene Set | 0.006009 | 86 | 0.03373 | 147 | Genes annotated by the GO term GO:0043122. Any process that modulates an I-kappaB kinase/NF-kappaB induced cascade. | www.broad.mit.e... |
Broad CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY | View Gene Set | 0.006129 | 13 | 0.03417 | 148 | Genes annotated by the GO term GO:0043624. The disaggregation of a protein complex into its constituent components occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. | www.broad.mit.e... |
Broad TRANSPORT | View Gene Set | 0.006416 | 777 | 0.03552 | 149 | Genes annotated by the GO term GO:0006810. The directed movement of substances (such as macromolecules small molecules ions) into out of within or between cells. | www.broad.mit.e... |
Broad SPLICEOSOME_ASSEMBLY | View Gene Set | 0.00664 | 13 | 0.03652 | 150 | Genes annotated by the GO term GO:0000245. The aggregation arrangement and bonding together of the spliceosome a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. | www.broad.mit.e... |
Broad HISTONE_MODIFICATION | View Gene Set | 0.006781 | 22 | 0.03705 | 151 | Genes annotated by the GO term GO:0016570. The covalent alteration of one or more amino acid residues within a histone protein. | www.broad.mit.e... |
Broad CYTOKINESIS | View Gene Set | 0.006882 | 19 | 0.03735 | 152 | Genes annotated by the GO term GO:0000910. A cellular process resulting in the division of the cytoplasm of a cell and its separation into two daughter cells. Cytokinesis usually occurs after growth replication and segregation of cellular components. | www.broad.mit.e... |
Broad RIBONUCLEOTIDE_METABOLIC_PROCESS | View Gene Set | 0.006993 | 14 | 0.03771 | 153 | Genes annotated by the GO term GO:0009259. The chemical reactions and pathways involving a ribonucleotide a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. | www.broad.mit.e... |
Broad COVALENT_CHROMATIN_MODIFICATION | View Gene Set | 0.007156 | 23 | 0.03834 | 154 | Genes annotated by the GO term GO:0016569. The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups. | www.broad.mit.e... |
Broad PROTEIN_IMPORT | View Gene Set | 0.007428 | 59 | 0.03942 | 155 | Genes annotated by the GO term GO:0017038. The directed movement of proteins into a cell or organelle. | www.broad.mit.e... |
Broad REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION_AND_BIOGENESIS | View Gene Set | 0.007454 | 124 | 0.03942 | 155 | Genes annotated by the GO term GO:0051128. Any process that modulates the frequency rate or extent of the processes involved in the formation arrangement of constituent parts or disassembly of cell structures including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. | www.broad.mit.e... |
Broad NITROGEN_COMPOUND_CATABOLIC_PROCESS | View Gene Set | 0.007521 | 28 | 0.03952 | 157 | Genes annotated by the GO term GO:0044270. The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds. | www.broad.mit.e... |
Broad GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | View Gene Set | 0.007771 | 122 | 0.04058 | 158 | Genes annotated by the GO term GO:0006091. The chemical reactions and pathways resulting in the formation of precursor metabolites substances from which energy is derived and the processes involved in the liberation of energy from these substances. | www.broad.mit.e... |
Broad POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION | View Gene Set | 0.008041 | 119 | 0.04146 | 159 | Genes annotated by the GO term GO:0009967. Any process that activates or increases the frequency rate or extent of signal transduction. | www.broad.mit.e... |
Broad NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | View Gene Set | 0.00803 | 83 | 0.04146 | 159 | Genes annotated by the GO term GO:0000122. Any process that stops prevents or reduces the frequency rate or extent of transcription from an RNA polymerase II promoter. | www.broad.mit.e... |
Broad ESTABLISHMENT_OF_LOCALIZATION | View Gene Set | 0.008303 | 851 | 0.04255 | 161 | Genes annotated by the GO term GO:0051234. The directed movement of a cell substance or cellular entity such as a protein complex or organelle to a specific location. | www.broad.mit.e... |
Broad BASE_EXCISION_REPAIR | View Gene Set | 0.008372 | 16 | 0.04263 | 162 | Genes annotated by the GO term GO:0006284. In base excision repair an altered base is removed by a DNA glycosylase enzyme followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. | www.broad.mit.e... |
Broad GLUTAMINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS | View Gene Set | 0.008831 | 14 | 0.0447 | 163 | Genes annotated by the GO term GO:0009064. The chemical reactions and pathways involving amino acids of the glutamine family comprising arginine glutamate glutamine and proline. | www.broad.mit.e... |
Broad PROTEIN_COMPLEX_DISASSEMBLY | View Gene Set | 0.009037 | 14 | 0.04491 | 164 | Genes annotated by the GO term GO:0043241. The disaggregation of a protein complex into its constituent components. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. | www.broad.mit.e... |
Broad CELLULAR_RESPONSE_TO_STIMULUS | View Gene Set | 0.008948 | 19 | 0.04491 | 164 | Genes annotated by the GO term GO:0051716. A change in state or activity of a cell (in terms of movement secretion enzyme production gene expression etc.) as a result of a stimulus. | www.broad.mit.e... |
Broad MACROMOLECULAR_COMPLEX_DISASSEMBLY | View Gene Set | 0.009037 | 15 | 0.04491 | 164 | Genes annotated by the GO term GO:0032984. The disaggregation of a macromolecular complex into its constituent components. | www.broad.mit.e... |
Broad CELL_PROLIFERATION_GO_0008283 | View Gene Set | 0.009128 | 501 | 0.0451 | 167 | Genes annotated by the GO term GO:0008283. The multiplication or reproduction of cells resulting in the expansion of a cell population. | www.broad.mit.e... |
Broad CELLULAR_COMPONENT_DISASSEMBLY | View Gene Set | 0.009415 | 33 | 0.04623 | 168 | Genes annotated by the GO term GO:0022411. A cellular process that results in the breakdown of a part of the cell. | www.broad.mit.e... |
Broad TRNA_PROCESSING | View Gene Set | 0.009894 | 10 | 0.0483 | 169 | Genes annotated by the GO term GO:0008033. The process by which a pre-tRNA molecule is converted to a mature tRNA ready for addition of an aminoacyl group. | www.broad.mit.e... |
Broad DNA_INTEGRITY_CHECKPOINT | View Gene Set | 0.01008 | 23 | 0.04892 | 170 | Genes annotated by the GO term GO:0031570. Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure. | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad CYTOPLASM | View Gene Set | 1.151e-59 | 2054 | 2.681e-57 | 1 | Genes annotated by the GO term GO:0005737. All of the contents of a cell excluding the plasma membrane and nucleus but including other subcellular structures. | www.broad.mit.e... |
Broad NUCLEUS | View Gene Set | 5.701e-59 | 1353 | 6.642e-57 | 2 | Genes annotated by the GO term GO:0005634. A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells the nucleus contains all of the cell's chromosomes except the organellar chromosomes and is the site of RNA synthesis and processing. In some species or in specialized cell types RNA metabolism or DNA replication may be absent. | www.broad.mit.e... |
Broad INTRACELLULAR_ORGANELLE_PART | View Gene Set | 6.593e-58 | 1144 | 5.12e-56 | 3 | Genes annotated by the GO term GO:0044446. A constituent part of an intracellular organelle an organized structure of distinctive morphology and function occurring within the cell. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. | www.broad.mit.e... |
Broad ORGANELLE_PART | View Gene Set | 3.605e-57 | 1149 | 2.1e-55 | 4 | Genes annotated by the GO term GO:0044422. Any constituent part of an organelle an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus mitochondria plastids vacuoles vesicles ribosomes and the cytoskeleton but excludes the plasma membrane. | www.broad.mit.e... |
Broad CYTOPLASMIC_PART | View Gene Set | 8.662e-47 | 1350 | 4.037e-45 | 5 | Genes annotated by the GO term GO:0044444. Any constituent part of the cytoplasm all of the contents of a cell excluding the plasma membrane and nucleus but including other subcellular structures. | www.broad.mit.e... |
Broad NUCLEAR_PART | View Gene Set | 9.74e-33 | 543 | 3.782e-31 | 6 | Genes annotated by the GO term GO:0044428. Any constituent part of the nucleus a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. | www.broad.mit.e... |
Broad MACROMOLECULAR_COMPLEX | View Gene Set | 6.083e-30 | 914 | 2.025e-28 | 7 | Genes annotated by the GO term GO:0032991. A stable assembly of two or more macromolecules i.e. proteins nucleic acids carbohydrates or lipids in which the constituent parts function together. | www.broad.mit.e... |
Broad ORGANELLE_MEMBRANE | View Gene Set | 1.163e-26 | 290 | 3.388e-25 | 8 | Genes annotated by the GO term GO:0031090. The lipid bilayer surrounding an organelle. | www.broad.mit.e... |
Broad ORGANELLE_LUMEN | View Gene Set | 1.107e-25 | 434 | 2.345e-24 | 9 | Genes annotated by the GO term GO:0043233. The volume enclosed by the membranes of a particular organelle e.g. endoplasmic reticulum lumen or the space between the two lipid bilayers of a double membrane surrounding an organelle e.g. nuclear membrane lumen. | www.broad.mit.e... |
Broad MEMBRANE_ENCLOSED_LUMEN | View Gene Set | 1.107e-25 | 434 | 2.345e-24 | 9 | Genes annotated by the GO term GO:0031974. The enclosed volume within a sealed membrane or between two sealed membranes. | www.broad.mit.e... |
Broad MITOCHONDRION | View Gene Set | 1.103e-25 | 335 | 2.345e-24 | 9 | Genes annotated by the GO term GO:0005739. A semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. | www.broad.mit.e... |
Broad RIBONUCLEOPROTEIN_COMPLEX | View Gene Set | 6.737e-23 | 129 | 1.308e-21 | 12 | Genes annotated by the GO term GO:0030529. A macromolecular complex containing both protein and RNA molecules. | www.broad.mit.e... |
Broad NUCLEAR_LUMEN | View Gene Set | 4.109e-20 | 365 | 7.365e-19 | 13 | Genes annotated by the GO term GO:0031981. The volume enclosed by the nuclear inner membrane. | www.broad.mit.e... |
Broad ENVELOPE | View Gene Set | 6.576e-20 | 165 | 1.021e-18 | 14 | Genes annotated by the GO term GO:0031975. A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers and may include a cell wall layer also includes the space between layers. | www.broad.mit.e... |
Broad ORGANELLE_ENVELOPE | View Gene Set | 6.576e-20 | 165 | 1.021e-18 | 14 | Genes annotated by the GO term GO:0031967. A double membrane structure enclosing an organelle including two lipid bilayers and the region between them. In some cases an organelle envelope may have more than two membranes. | www.broad.mit.e... |
Broad MITOCHONDRIAL_PART | View Gene Set | 8.311e-19 | 140 | 1.21e-17 | 16 | Genes annotated by the GO term GO:0044429. Any constituent part of a mitochondrion a semiautonomous self replicating organelle that occurs in varying numbers shapes and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. | www.broad.mit.e... |
Broad NON_MEMBRANE_BOUND_ORGANELLE | View Gene Set | 1.238e-18 | 613 | 1.602e-17 | 17 | Genes annotated by the GO term GO:0043228. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane. Includes ribosomes the cytoskeleton and chromosomes. | www.broad.mit.e... |
Broad INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE | View Gene Set | 1.238e-18 | 613 | 1.602e-17 | 17 | Genes annotated by the GO term GO:0043232. Organized structure of distinctive morphology and function not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes the cytoskeleton and chromosomes. | www.broad.mit.e... |
Broad ENDOMEMBRANE_SYSTEM | View Gene Set | 4.148e-18 | 213 | 4.902e-17 | 19 | Genes annotated by the GO term GO:0012505. A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum Golgi bodies vesicles cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. | www.broad.mit.e... |
Broad PROTEIN_COMPLEX | View Gene Set | 4.208e-18 | 799 | 4.902e-17 | 19 | Genes annotated by the GO term GO:0043234. Any protein group composed of two or more subunits which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups such as nucleic acids metal ions or carbohydrate groups. | www.broad.mit.e... |
Broad ENDOPLASMIC_RETICULUM | View Gene Set | 2.996e-15 | 282 | 3.324e-14 | 21 | Genes annotated by the GO term GO:0005783. The irregular network of unit membranes visible only by electron microscopy that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels which are often expanded into slitlike cavities called cisternae. The ER takes two forms rough (or granular) with ribosomes adhering to the outer surface and smooth (with no ribosomes attached). | www.broad.mit.e... |
Broad MITOCHONDRIAL_MEMBRANE | View Gene Set | 1.543e-14 | 85 | 1.634e-13 | 22 | Genes annotated by the GO term GO:0031966. Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. | www.broad.mit.e... |
Broad MITOCHONDRIAL_ENVELOPE | View Gene Set | 2.358e-13 | 95 | 2.389e-12 | 23 | Genes annotated by the GO term GO:0005740. The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space. | www.broad.mit.e... |
Broad NUCLEOLUS | View Gene Set | 1.008e-12 | 116 | 9.784e-12 | 24 | Genes annotated by the GO term GO:0005730. A small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA the processing of this RNA into 5.8S 18S and 28S components of ribosomal RNA and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. | www.broad.mit.e... |
Broad NUCLEOPLASM | View Gene Set | 2.029e-12 | 266 | 1.891e-11 | 25 | Genes annotated by the GO term GO:0005654. That part of the nuclear content other than the chromosomes or the nucleolus. | www.broad.mit.e... |
Broad ENDOPLASMIC_RETICULUM_PART | View Gene Set | 6.448e-11 | 93 | 5.779e-10 | 26 | Genes annotated by the GO term GO:0044432. Any constituent part of the endoplasmic reticulum the irregular network of unit membranes visible only by electron microscopy that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels which are often expanded into slitlike cavities called cisternae. | www.broad.mit.e... |
Broad MITOCHONDRIAL_INNER_MEMBRANE | View Gene Set | 1.605e-10 | 66 | 1.385e-09 | 27 | Genes annotated by the GO term GO:0005743. The inner i.e. lumen-facing lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. | www.broad.mit.e... |
Broad ORGANELLE_INNER_MEMBRANE | View Gene Set | 3.383e-10 | 74 | 2.718e-09 | 28 | Genes annotated by the GO term GO:0019866. The inner i.e. lumen-facing lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites. | www.broad.mit.e... |
Broad MITOCHONDRIAL_MEMBRANE_PART | View Gene Set | 3.274e-10 | 52 | 2.718e-09 | 28 | Genes annotated by the GO term GO:0044455. Any constituent part of the mitochondrial membrane either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. | www.broad.mit.e... |
Broad CHROMOSOME | View Gene Set | 5.714e-10 | 122 | 4.438e-09 | 30 | Genes annotated by the GO term GO:0005694. A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. | www.broad.mit.e... |
Broad RIBOSOME | View Gene Set | 1.553e-09 | 39 | 1.167e-08 | 31 | Genes annotated by the GO term GO:0005840. An intracellular organelle about 200 A in diameter consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits one large and one small each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients expressed in Svedberg units (symbol: S). Hence the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes eukaryotes mitochondria and chloroplasts have characteristically distinct ribosomal proteins. | www.broad.mit.e... |
Broad NUCLEAR_ENVELOPE_ENDOPLASMIC_RETICULUM_NETWORK | View Gene Set | 6.194e-09 | 91 | 4.51e-08 | 32 | Genes annotated by the GO term GO:0042175. The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum. | www.broad.mit.e... |
Broad ENDOPLASMIC_RETICULUM_MEMBRANE | View Gene Set | 1.061e-08 | 82 | 7.494e-08 | 33 | Genes annotated by the GO term GO:0005789. The lipid bilayer surrounding the endoplasmic reticulum. | www.broad.mit.e... |
Broad NUCLEAR_ENVELOPE | View Gene Set | 1.219e-08 | 71 | 8.354e-08 | 34 | Genes annotated by the GO term GO:0005635. The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space a gap of width 20-40 nm (also called the perinuclear space). | www.broad.mit.e... |
Broad CHROMOSOMAL_PART | View Gene Set | 3.44e-08 | 95 | 2.29e-07 | 35 | Genes annotated by the GO term GO:0044427. Any constituent part of a chromosome a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. | www.broad.mit.e... |
Broad SPLICEOSOME | View Gene Set | 1.388e-07 | 44 | 8.984e-07 | 36 | Genes annotated by the GO term GO:0005681. A ribonucleoprotein complex containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron. | www.broad.mit.e... |
Broad MITOCHONDRIAL_MATRIX | View Gene Set | 1.908e-07 | 46 | 1.17e-06 | 37 | Genes annotated by the GO term GO:0005759. The gel-like material with considerable fine structure that lies in the matrix space or lumen of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and in some organisms the enzymes concerned with fatty-acid oxidation. | www.broad.mit.e... |
Broad MITOCHONDRIAL_LUMEN | View Gene Set | 1.908e-07 | 46 | 1.17e-06 | 37 | Genes annotated by the GO term GO:0031980. The volume enclosed by the mitochondrial inner membrane. | www.broad.mit.e... |
Broad NUCLEAR_MEMBRANE | View Gene Set | 3.049e-07 | 48 | 1.822e-06 | 39 | Genes annotated by the GO term GO:0031965. Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. | www.broad.mit.e... |
Broad GOLGI_APPARATUS | View Gene Set | 3.67e-07 | 222 | 2.138e-06 | 40 | Genes annotated by the GO term GO:0005794. A compound membranous cytoplasmic organelle of eukaryotic cells consisting of flattened ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle while in invertebrates and plants where they are known usually as dictyosomes there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis in the vicinity of the cis face trans in the vicinity of the trans face and medial lying between the cis and trans regions. | www.broad.mit.e... |
Broad NUCLEOPLASM_PART | View Gene Set | 3.873e-07 | 202 | 2.201e-06 | 41 | Genes annotated by the GO term GO:0044451. Any constituent part of the nucleoplasm that part of the nuclear content other than the chromosomes or the nucleolus. | www.broad.mit.e... |
Broad GOLGI_APPARATUS_PART | View Gene Set | 4.033e-07 | 98 | 2.237e-06 | 42 | Genes annotated by the GO term GO:0044431. Any constituent part of the Golgi apparatus a compound membranous cytoplasmic organelle of eukaryotic cells consisting of flattened ribosome-free vesicles arranged in a more or less regular stack. | www.broad.mit.e... |
Broad NUCLEAR_PORE | View Gene Set | 8.752e-07 | 29 | 4.742e-06 | 43 | Genes annotated by the GO term GO:0005643. Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell where the inner and outer nuclear membranes are joined. | www.broad.mit.e... |
Broad NUCLEAR_MEMBRANE_PART | View Gene Set | 9.936e-07 | 40 | 5.262e-06 | 44 | Genes annotated by the GO term GO:0044453. Any constituent part of the nuclear membrane the envelope that surrounds the nucleus of eukaryotic cells. | www.broad.mit.e... |
Broad SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX | View Gene Set | 1.09e-06 | 20 | 5.523e-06 | 45 | Genes annotated by the GO term GO:0030532. A complex composed of RNA of the small nuclear RNA (snRNA) class and protein found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain e.g. U1 snRNP or U4/U6 snRNP. Many but not all of these complexes are involved in splicing of nuclear mRNAs. | www.broad.mit.e... |
Broad PROTEASOME_COMPLEX | View Gene Set | 1.069e-06 | 23 | 5.523e-06 | 45 | Genes annotated by the GO term GO:0000502. A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. | www.broad.mit.e... |
Broad HETEROGENEOUS_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX | View Gene Set | 2.225e-06 | 9 | 1.103e-05 | 47 | Genes annotated by the GO term GO:0030530. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II that which is translated into protein) with protein which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA. | www.broad.mit.e... |
Broad RIBOSOMAL_SUBUNIT | View Gene Set | 5.688e-06 | 20 | 2.761e-05 | 48 | Genes annotated by the GO term GO:0033279. Either of the two ribonucleoprotein complexes that associate to form a ribosome. | www.broad.mit.e... |
Broad PORE_COMPLEX | View Gene Set | 6.775e-06 | 34 | 3.221e-05 | 49 | Genes annotated by the GO term GO:0046930. Any small opening in a membrane that allows the passage of gases and/or liquids. | www.broad.mit.e... |
Broad INTEGRAL_TO_ORGANELLE_MEMBRANE | View Gene Set | 8.804e-06 | 49 | 4.022e-05 | 50 | Genes annotated by the GO term GO:0031301. Penetrating at least one phospholipid bilayer of an organelle membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. | www.broad.mit.e... |
Broad INTRINSIC_TO_ORGANELLE_MEMBRANE | View Gene Set | 8.768e-06 | 51 | 4.022e-05 | 50 | Genes annotated by the GO term GO:0031300. Located in an organelle membrane such that some covalently attached portion of the gene product for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor spans or is embedded in one or both leaflets of the membrane. | www.broad.mit.e... |
Broad ORGANELLAR_RIBOSOME | View Gene Set | 2.322e-05 | 22 | 0.0001021 | 52 | Genes annotated by the GO term GO:0000313. A ribosome contained within a subcellular organelle. | www.broad.mit.e... |
Broad MITOCHONDRIAL_RIBOSOME | View Gene Set | 2.322e-05 | 22 | 0.0001021 | 52 | Genes annotated by the GO term GO:0005761. A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. | www.broad.mit.e... |
Broad GOLGI_MEMBRANE | View Gene Set | 2.672e-05 | 43 | 0.0001153 | 54 | Genes annotated by the GO term GO:0000139. The lipid bilayer surrounding any of the compartments of the Golgi apparatus. | www.broad.mit.e... |
Broad MITOCHONDRIAL_OUTER_MEMBRANE | View Gene Set | 3.398e-05 | 18 | 0.0001439 | 55 | Genes annotated by the GO term GO:0005741. The outer i.e. cytoplasm-facing lipid bilayer of the mitochondrial envelope. | www.broad.mit.e... |
Broad OLIGOSACCHARYL_TRANSFERASE_COMPLEX | View Gene Set | 4.672e-05 | 9 | 0.0001944 | 56 | Genes annotated by the GO term GO:0008250. A multisubunit protein complex in the endoplasmic reticulum membrane of eukaryotes that transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins; includes at least nine different subunits at least in yeast. | www.broad.mit.e... |
Broad INTRINSIC_TO_ENDOPLASMIC_RETICULUM_MEMBRANE | View Gene Set | 5.2e-05 | 24 | 0.0002089 | 57 | Genes annotated by the GO term GO:0031227. Located in the endoplasmic reticulum membrane such that some covalently attached portion of the gene product for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor spans or is embedded in one or both leaflets of the membrane. | www.broad.mit.e... |
Broad INTEGRAL_TO_ENDOPLASMIC_RETICULUM_MEMBRANE | View Gene Set | 5.2e-05 | 24 | 0.0002089 | 57 | Genes annotated by the GO term GO:0030176. Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. | www.broad.mit.e... |
Broad OUTER_MEMBRANE | View Gene Set | 6.986e-05 | 25 | 0.0002759 | 59 | Genes annotated by the GO term GO:0019867. The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. | www.broad.mit.e... |
Broad SPINDLE | View Gene Set | 0.0001092 | 37 | 0.0004242 | 60 | Genes annotated by the GO term GO:0005819. The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. | www.broad.mit.e... |
Broad ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT | View Gene Set | 0.0001181 | 11 | 0.0004368 | 61 | Genes annotated by the GO term GO:0000314. The smaller of the two subunits of an organellar ribosome. | www.broad.mit.e... |
Broad MITOCHONDRIAL_SMALL_RIBOSOMAL_SUBUNIT | View Gene Set | 0.0001181 | 11 | 0.0004368 | 61 | Genes annotated by the GO term GO:0005763. The smaller of the two subunits of a mitochondrial ribosome. | www.broad.mit.e... |
Broad SMALL_RIBOSOMAL_SUBUNIT | View Gene Set | 0.0001181 | 11 | 0.0004368 | 61 | Genes annotated by the GO term GO:0015935. The smaller of the two subunits of a ribosome. | www.broad.mit.e... |
Broad CYTOSOL | View Gene Set | 0.00015 | 203 | 0.000546 | 64 | Genes annotated by the GO term GO:0005829. That part of the cytoplasm that does not contain membranous or particulate subcellular components. | www.broad.mit.e... |
Broad MITOCHONDRIAL_RESPIRATORY_CHAIN | View Gene Set | 0.0001766 | 24 | 0.0006235 | 65 | Genes annotated by the GO term GO:0005746. The protein complexes that form the mitochondrial electron transport system (the respiratory chain). Complexes I III and IV can transport protons if embedded in an oriented membrane such as an intact mitochondrial inner membrane. | www.broad.mit.e... |
Broad ENDOPLASMIC_RETICULUM_LUMEN | View Gene Set | 0.0001764 | 12 | 0.0006235 | 65 | Genes annotated by the GO term GO:0005788. The volume enclosed by the membranes of the endoplasmic reticulum. | www.broad.mit.e... |
Broad ORGANELLE_OUTER_MEMBRANE | View Gene Set | 0.0002 | 24 | 0.0006955 | 67 | Genes annotated by the GO term GO:0031968. The outer i.e. cytoplasm-facing lipid bilayer of an organelle envelope. | www.broad.mit.e... |
Broad EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX | View Gene Set | 0.0002051 | 10 | 0.0007029 | 68 | Genes annotated by the GO term GO:0005852. A complex of several polypeptides that plays at least two important roles in protein synthesis: First eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. | www.broad.mit.e... |
Broad NUCLEAR_CHROMOSOME | View Gene Set | 0.000275 | 53 | 0.0009288 | 69 | Genes annotated by the GO term GO:0000228. A chromosome found in the nucleus of a eukaryotic cell. | www.broad.mit.e... |
Broad KINETOCHORE | View Gene Set | 0.0003246 | 25 | 0.001074 | 70 | Genes annotated by the GO term GO:0000776. A multisubunit complex that is located at the pericentric region of DNA and provides an attachment point for the spindle microtubules. | www.broad.mit.e... |
Broad ER_GOLGI_INTERMEDIATE_COMPARTMENT | View Gene Set | 0.0003274 | 22 | 0.001074 | 70 | Genes annotated by the GO term GO:0005793. A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex with a distinctive membrane protein composition; involved in ER-to-Golgi transport. | www.broad.mit.e... |
Broad CHROMATIN | View Gene Set | 0.0004093 | 35 | 0.001325 | 72 | Genes annotated by the GO term GO:0000785. The ordered and organized complex of DNA and protein that forms the chromosome. | www.broad.mit.e... |
Broad MICROTUBULE | View Gene Set | 0.0004407 | 31 | 0.001407 | 73 | Genes annotated by the GO term GO:0005874. Any of the long generally straight hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation e.g. in the spindle. | www.broad.mit.e... |
Broad CONDENSED_CHROMOSOME | View Gene Set | 0.0004952 | 32 | 0.001559 | 74 | Genes annotated by the GO term GO:0000793. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. | www.broad.mit.e... |
Broad CHROMOSOMEPERICENTRIC_REGION | View Gene Set | 0.00059 | 31 | 0.001833 | 75 | Genes annotated by the GO term GO:0000775. The central region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes this region corresponds to a single area of the chromosome whereas in holocentric chromosomes it is evenly distributed along the chromosome. | www.broad.mit.e... |
Broad MICROTUBULE_CYTOSKELETON | View Gene Set | 0.0006831 | 146 | 0.002094 | 76 | Genes annotated by the GO term GO:0015630. The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. | www.broad.mit.e... |
Broad ENDOSOME | View Gene Set | 0.0006978 | 64 | 0.002112 | 77 | Genes annotated by the GO term GO:0005768. A membrane-bound organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation. | www.broad.mit.e... |
Broad SPINDLE_MICROTUBULE | View Gene Set | 0.0007254 | 15 | 0.002167 | 78 | Genes annotated by the GO term GO:0005876. Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. | www.broad.mit.e... |
Broad GOLGI_ASSOCIATED_VESICLE | View Gene Set | 0.0008545 | 27 | 0.00252 | 79 | Genes annotated by the GO term GO:0005798. Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. | www.broad.mit.e... |
Broad CYTOSKELETON | View Gene Set | 0.0009906 | 359 | 0.002885 | 80 | Genes annotated by the GO term GO:0005856. Any of the various filamentous elements that form the internal framework of cells and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments microfilaments microtubules the microtrabecular lattice and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions including cellular movement cell division endocytosis and movement of organelles. | www.broad.mit.e... |
Broad PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX | View Gene Set | 0.001066 | 15 | 0.003066 | 81 | Genes annotated by the GO term GO:0016469. A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0 V0 or A0) that carries out proton transport and a cytoplasmic compartment sector (F1 V1 or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient whereas F-type ATPases also known as ATP synthases normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type A-type ATPases have been found in archaea and are closely related to eukaryotic V-type ATPases but are reversible. | www.broad.mit.e... |
Broad TRANSCRIPTION_FACTOR_COMPLEX | View Gene Set | 0.00115 | 84 | 0.003266 | 82 | Genes annotated by the GO term GO:0005667. Any complex distinct from RNA polymerase including one or more polypeptides capable of binding DNA at promoters or at cis-acting regulatory sequences and regulating transcription. | www.broad.mit.e... |
Broad NUCLEOLAR_PART | View Gene Set | 0.001258 | 16 | 0.00353 | 83 | Genes annotated by the GO term GO:0044452. Any constituent part of a nucleolus a small dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein is not bounded by a limiting membrane and is not seen during mitosis. | www.broad.mit.e... |
Broad REPLICATION_FORK | View Gene Set | 0.001367 | 18 | 0.003792 | 84 | Genes annotated by the GO term GO:0005657. The Y-shaped region of a replicating DNA molecule resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. | www.broad.mit.e... |
Broad UBIQUITIN_LIGASE_COMPLEX | View Gene Set | 0.001518 | 26 | 0.004161 | 85 | Genes annotated by the GO term GO:0000151. A protein complex that includes a ubiquitin-protein ligase (E3) and other proteins that may confer substrate specificity on the complex. | www.broad.mit.e... |
Broad GOLGI_STACK | View Gene Set | 0.001696 | 13 | 0.004596 | 86 | Genes annotated by the GO term GO:0005795. The set of thin flattened membrane-bounded compartments called cisternae that form the central portion of the Golgi complex. The stack usually comprises cis medial and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack. | www.broad.mit.e... |
Broad EARLY_ENDOSOME | View Gene Set | 0.001798 | 18 | 0.004816 | 87 | Genes annotated by the GO term GO:0005769. Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered. | www.broad.mit.e... |
Broad MICROBODY | View Gene Set | 0.002264 | 46 | 0.005928 | 88 | Genes annotated by the GO term GO:0042579. Cytoplasmic organelles spherical or oval in shape that are bounded by a single membrane and contain oxidative enzymes especially those utilizing hydrogen peroxide (H2O2). | www.broad.mit.e... |
Broad PEROXISOME | View Gene Set | 0.002264 | 46 | 0.005928 | 88 | Genes annotated by the GO term GO:0005777. A small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2). | www.broad.mit.e... |
Broad NADH_DEHYDROGENASE_COMPLEX | View Gene Set | 0.002962 | 15 | 0.007501 | 90 | Genes annotated by the GO term GO:0030964. An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyses the transfer of a pair of electrons from NADH to a quinone. | www.broad.mit.e... |
Broad MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I | View Gene Set | 0.002962 | 15 | 0.007501 | 90 | Genes annotated by the GO term GO:0005747. A part of the respiratory chain located in the mitochondrion. It contains about 25 different polypeptide subunits including NADH dehydrogenase (ubiquinone) flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III) and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. | www.broad.mit.e... |
Broad RESPIRATORY_CHAIN_COMPLEX_I | View Gene Set | 0.002962 | 15 | 0.007501 | 90 | Genes annotated by the GO term GO:0045271. Respiratory chain complex I is an enzyme of the respiratory chain. It consists of at least 34 polypeptide chains and is L-shaped with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex. | www.broad.mit.e... |
Broad NUCLEAR_BODY | View Gene Set | 0.003257 | 31 | 0.00816 | 93 | Genes annotated by the GO term GO:0016604. Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. | www.broad.mit.e... |
Broad TRANSPORT_VESICLE | View Gene Set | 0.003312 | 29 | 0.00821 | 94 | Genes annotated by the GO term GO:0030133. Any of the vesicles of the constitutive secretory pathway which carry cargo from the endoplasmic reticulum to the Golgi between Golgi cisternae and to destinations within or outside the cell. | www.broad.mit.e... |
Broad CYTOSKELETAL_PART | View Gene Set | 0.0051 | 231 | 0.01251 | 95 | Genes annotated by the GO term GO:0044430. Any constituent part of the cytoskeleton a cellular scaffolding or skeleton that maintains cell shape enables some cell motion (using structures such as flagella and cilia) and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments microfilaments microtubules and the microtrabecular lattice. | www.broad.mit.e... |
Broad CYTOPLASMIC_VESICLE_MEMBRANE | View Gene Set | 0.007258 | 26 | 0.01726 | 96 | Genes annotated by the GO term GO:0030659. The lipid bilayer surrounding a cytoplasmic vesicle. | www.broad.mit.e... |
Broad HISTONE_DEACETYLASE_COMPLEX | View Gene Set | 0.007209 | 18 | 0.01726 | 96 | Genes annotated by the GO term GO:0000118. Complex that possesses histone deacetylase activity. | www.broad.mit.e... |
Broad CYTOPLASMIC_VESICLE_PART | View Gene Set | 0.007258 | 26 | 0.01726 | 96 | Genes annotated by the GO term GO:0044433. Any constituent part of cytoplasmic vesicle a vesicle formed of membrane or protein found in the cytoplasm of a cell. | www.broad.mit.e... |
Broad VESICLE_MEMBRANE | View Gene Set | 0.007406 | 28 | 0.01743 | 99 | Genes annotated by the GO term GO:0012506. The lipid bilayer surrounding any membrane-bounded vesicle in the cell. | www.broad.mit.e... |
Broad PERINUCLEAR_REGION_OF_CYTOPLASM | View Gene Set | 0.008359 | 55 | 0.01948 | 100 | Genes annotated by the GO term GO:0048471. Cytoplasm situated near or occurring around the nucleus. | www.broad.mit.e... |
Broad INTRINSIC_TO_GOLGI_MEMBRANE | View Gene Set | 0.009547 | 15 | 0.02202 | 101 | Genes annotated by the GO term GO:0031228. Located in the Golgi membrane such that some covalently attached portion of the gene product for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor spans or is embedded in one or both leaflets of the membrane. | www.broad.mit.e... |
Broad TRANS_GOLGI_NETWORK | View Gene Set | 0.01317 | 21 | 0.03009 | 102 | Genes annotated by the GO term GO:0005802. The network of interconnected tubular and cisternal structures located at the side of the Golgi apparatus distal to the endoplasmic reticulum from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. | www.broad.mit.e... |
Broad NUCLEAR_CHROMOSOME_PART | View Gene Set | 0.01364 | 33 | 0.03085 | 103 | Genes annotated by the GO term GO:0044454. Any constituent part of a nuclear chromosome a chromosome found in the nucleus of a eukaryotic cell. | www.broad.mit.e... |
Broad COATED_VESICLE | View Gene Set | 0.01415 | 45 | 0.0317 | 104 | Genes annotated by the GO term GO:0030135. Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin whereas others are made from other proteins. | www.broad.mit.e... |
Broad TRANS_GOLGI_NETWORK_TRANSPORT_VESICLE | View Gene Set | 0.01622 | 11 | 0.03599 | 105 | Genes annotated by the GO term GO:0030140. A vesicle that mediates transport between the trans-Golgi network and other parts of the cell. | www.broad.mit.e... |
Broad NUCLEAR_UBIQUITIN_LIGASE_COMPLEX | View Gene Set | 0.01669 | 11 | 0.03668 | 106 | Genes annotated by the GO term GO:0000152. A ubiquitin ligase complex found in the nucleus. | www.broad.mit.e... |
Broad PML_BODY | View Gene Set | 0.01941 | 13 | 0.04226 | 107 | Genes annotated by the GO term GO:0016605. A class of nuclear body; they react against SP100 auto-antibodies (PML promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection. | www.broad.mit.e... |
Broad MEMBRANE_BOUND_VESICLE | View Gene Set | 0.02208 | 113 | 0.04763 | 108 | Genes annotated by the GO term GO:0031988. Any small fluid-filled spherical organelle enclosed by a lipid bilayer. | www.broad.mit.e... |
Broad CYTOPLASMIC_MEMBRANE_BOUND_VESICLE | View Gene Set | 0.02332 | 111 | 0.04985 | 109 | Genes annotated by the GO term GO:0016023. A membrane-bound vesicle found in the cytoplasm of the cell. | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Broad RNA_BINDING | View Gene Set | 7.234e-39 | 236 | 2.865e-36 | 1 | Genes annotated by the GO term GO:0003723. Interacting selectively with an RNA molecule or a portion thereof. | www.broad.mit.e... |
Broad STRUCTURAL_CONSTITUENT_OF_RIBOSOME | View Gene Set | 3.088e-22 | 80 | 6.115e-20 | 2 | Genes annotated by the GO term GO:0003735. The action of a molecule that contributes to the structural integrity of the ribosome. | www.broad.mit.e... |
Broad TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING | View Gene Set | 7.14e-11 | 39 | 9.425e-09 | 3 | Genes annotated by the GO term GO:0008135. Functions during translation by binding nucleic acids during polypeptide synthesis at the ribosome. | www.broad.mit.e... |
Broad TRANSLATION_REGULATOR_ACTIVITY | View Gene Set | 1.674e-10 | 41 | 1.657e-08 | 4 | Genes annotated by the GO term GO:0045182. Any substance involved in the initiation activation perpetuation repression or termination of polypeptide synthesis at the ribosome. | www.broad.mit.e... |
Broad HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES | View Gene Set | 2.814e-10 | 224 | 2.229e-08 | 5 | Genes annotated by the GO term GO:0016817. Catalysis of the hydrolysis of any acid anhydride. | www.broad.mit.e... |
Broad PYROPHOSPHATASE_ACTIVITY | View Gene Set | 5.957e-10 | 222 | 3.931e-08 | 6 | Genes annotated by the GO term GO:0016462. Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups leaving one phosphate on each of the two fragments. | www.broad.mit.e... |
Broad TRANSLATION_INITIATION_FACTOR_ACTIVITY | View Gene Set | 1.955e-09 | 24 | 1.106e-07 | 7 | Genes annotated by the GO term GO:0003743. Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. | www.broad.mit.e... |
Broad NUCLEOSIDE_TRIPHOSPHATASE_ACTIVITY | View Gene Set | 2.333e-09 | 208 | 1.155e-07 | 8 | Genes annotated by the GO term GO:0017111. Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate. | www.broad.mit.e... |
Broad LIGASE_ACTIVITY | View Gene Set | 3.948e-08 | 97 | 1.737e-06 | 9 | Genes annotated by the GO term GO:0016874. Catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. | www.broad.mit.e... |
Broad UNFOLDED_PROTEIN_BINDING | View Gene Set | 4.99e-08 | 41 | 1.976e-06 | 10 | Genes annotated by the GO term GO:0051082. Interacting selectively with an unfolded protein. | www.broad.mit.e... |
Broad TRANSCRIPTION_FACTOR_BINDING | View Gene Set | 4.176e-07 | 300 | 1.503e-05 | 11 | Genes annotated by the GO term GO:0008134. Interacting selectively with a transcription factor any protein required to initiate or regulate transcription. | www.broad.mit.e... |
Broad STRUCTURE_SPECIFIC_DNA_BINDING | View Gene Set | 6.483e-07 | 55 | 2.061e-05 | 12 | Genes annotated by the GO term GO:0043566. Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. | www.broad.mit.e... |
Broad ATPASE_ACTIVITY | View Gene Set | 6.767e-07 | 109 | 2.061e-05 | 12 | Genes annotated by the GO term GO:0016887. Catalysis of the reaction: ATP + H2O = ADP + phosphate. May or may not be coupled to another reaction. | www.broad.mit.e... |
Broad SIGNAL_SEQUENCE_BINDING | View Gene Set | 9.465e-07 | 15 | 2.677e-05 | 14 | Genes annotated by the GO term GO:0005048. Interacting selectively with a signal sequence a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized. | www.broad.mit.e... |
Broad DNA_BINDING | View Gene Set | 1.897e-06 | 587 | 5.009e-05 | 15 | Genes annotated by the GO term GO:0003677. Interacting selectively with DNA (deoxyribonucleic acid). | www.broad.mit.e... |
Broad SINGLE_STRANDED_DNA_BINDING | View Gene Set | 4.111e-06 | 34 | 0.0001017 | 16 | Genes annotated by the GO term GO:0003697. Interacting selectively with single-stranded DNA. | www.broad.mit.e... |
Broad HELICASE_ACTIVITY | View Gene Set | 1.162e-05 | 49 | 0.0002706 | 17 | Genes annotated by the GO term GO:0004386. Catalysis of the unwinding of a DNA or RNA duplex. | www.broad.mit.e... |
Broad MRNA_BINDING | View Gene Set | 3.158e-05 | 22 | 0.0006949 | 18 | Genes annotated by the GO term GO:0003729. Interacting selectively with pre-messenger RNA (pre-mRNA) or messenger RNA (mRNA). | www.broad.mit.e... |
Broad DAMAGED_DNA_BINDING | View Gene Set | 5.094e-05 | 21 | 0.0009606 | 19 | Genes annotated by the GO term GO:0003684. Interacting selectively with damaged DNA. | www.broad.mit.e... |
Broad STRUCTURAL_MOLECULE_ACTIVITY | View Gene Set | 4.795e-05 | 243 | 0.0009606 | 19 | Genes annotated by the GO term GO:0005198. The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell. | www.broad.mit.e... |
Broad LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS | View Gene Set | 4.96e-05 | 14 | 0.0009606 | 19 | Genes annotated by the GO term GO:0016875. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. | www.broad.mit.e... |
Broad ATP_DEPENDENT_HELICASE_ACTIVITY | View Gene Set | 9.633e-05 | 26 | 0.001659 | 22 | Genes annotated by the GO term GO:0008026. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the unwinding of a DNA or RNA helix. | www.broad.mit.e... |
Broad ATPASE_ACTIVITY_COUPLED | View Gene Set | 9.501e-05 | 92 | 0.001659 | 22 | Genes annotated by the GO term GO:0042623. Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction for example ion transport across a membrane. | www.broad.mit.e... |
Broad RNA_SPLICING_FACTOR_ACTIVITYTRANSESTERIFICATION_MECHANISM | View Gene Set | 0.0001028 | 14 | 0.001695 | 24 | Genes annotated by the GO term GO:0031202. An activity which binds RNA and functions to assist splicing of substrate RNA(s) by facilitating the formation and stabilization of a catalytic conformation in which the splice junctions of the RNA(s) to be spliced are positioned for a transesterification reaction that occurs between two sites within the RNA(s) to be spliced. | www.broad.mit.e... |
Broad OXIDOREDUCTASE_ACTIVITY | View Gene Set | 0.0001311 | 280 | 0.002076 | 25 | Genes annotated by the GO term GO:0016491. Catalysis of an oxidation-reduction (redox) reaction a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized while the other acts as hydrogen or electron acceptor and becomes reduced. | www.broad.mit.e... |
Broad LIGASE_ACTIVITY_FORMING_CARBON_NITROGEN_BONDS | View Gene Set | 0.0001536 | 68 | 0.00231 | 26 | Genes annotated by the GO term GO:0016879. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. | www.broad.mit.e... |
Broad DOUBLE_STRANDED_DNA_BINDING | View Gene Set | 0.0001633 | 32 | 0.00231 | 26 | Genes annotated by the GO term GO:0003690. Interacting selectively with double-stranded DNA. | www.broad.mit.e... |
Broad CHROMATIN_BINDING | View Gene Set | 0.000158 | 32 | 0.00231 | 26 | Genes annotated by the GO term GO:0003682. Interacting selectively with chromatin the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. | www.broad.mit.e... |
Broad TRANSCRIPTION_COFACTOR_ACTIVITY | View Gene Set | 0.0002102 | 222 | 0.002871 | 29 | Genes annotated by the GO term GO:0003712. The function that links a sequence-specific transcription factor to the core RNA polymerase II complex but does not bind DNA itself. | www.broad.mit.e... |
Broad DNA_DEPENDENT_ATPASE_ACTIVITY | View Gene Set | 0.0002618 | 22 | 0.003456 | 30 | Genes annotated by the GO term GO:0008094. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single- or double-stranded DNA; drives another reaction. | www.broad.mit.e... |
Broad RNA_DEPENDENT_ATPASE_ACTIVITY | View Gene Set | 0.0002712 | 18 | 0.003464 | 31 | Genes annotated by the GO term GO:0008186. Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of RNA; drives another reaction. | www.broad.mit.e... |
Broad RNA_HELICASE_ACTIVITY | View Gene Set | 0.0003348 | 24 | 0.003936 | 32 | Genes annotated by the GO term GO:0003724. Catalysis of the unwinding of an RNA helix. | www.broad.mit.e... |
Broad METHYLTRANSFERASE_ACTIVITY | View Gene Set | 0.0003379 | 36 | 0.003936 | 32 | Genes annotated by the GO term GO:0008168. Catalysis of the transfer of a methyl group to an acceptor molecule. | www.broad.mit.e... |
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | View Gene Set | 0.0003319 | 414 | 0.003936 | 32 | Genes annotated by the GO term GO:0016772. Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). | www.broad.mit.e... |
Broad GTPASE_ACTIVITY | View Gene Set | 0.0005149 | 98 | 0.005826 | 35 | Genes annotated by the GO term GO:0003924. Catalysis of the reaction: GTP + H2O = GDP + phosphate. | www.broad.mit.e... |
Broad EXONUCLEASE_ACTIVITY | View Gene Set | 0.0006793 | 18 | 0.007472 | 36 | Genes annotated by the GO term GO:0004527. Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. | www.broad.mit.e... |
Broad NUCLEOBASENUCLEOSIDENUCLEOTIDE_KINASE_ACTIVITY | View Gene Set | 0.0007314 | 24 | 0.007828 | 37 | Genes annotated by the GO term GO:0019205. Catalysis of the transfer of a phosphate group usually from ATP or GTP to a nucleobase nucleoside nucleotide or polynucleotide substrate. | www.broad.mit.e... |
Broad ATP_DEPENDENT_RNA_HELICASE_ACTIVITY | View Gene Set | 0.0007945 | 17 | 0.00828 | 38 | Genes annotated by the GO term GO:0004004. Catalysis of the reaction: ATP + H2O = ADP + phosphate driving the unwinding of an RNA helix. | www.broad.mit.e... |
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS | View Gene Set | 0.0009892 | 37 | 0.01004 | 39 | Genes annotated by the GO term GO:0016741. Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor). | www.broad.mit.e... |
Broad PROTEIN_HETERODIMERIZATION_ACTIVITY | View Gene Set | 0.001074 | 77 | 0.01064 | 40 | Genes annotated by the GO term GO:0046982. Interacting selectively with a nonidentical protein to form a heterodimer. | www.broad.mit.e... |
Broad DOUBLE_STRANDED_RNA_BINDING | View Gene Set | 0.001205 | 17 | 0.01104 | 41 | Genes annotated by the GO term GO:0003725. Interacting selectively with double-stranded RNA. | www.broad.mit.e... |
Broad TRANSITION_METAL_ION_BINDING | View Gene Set | 0.001216 | 110 | 0.01104 | 41 | Genes annotated by the GO term GO:0046914. Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium manganese iron copper cobalt nickel molybdenum and silver. | www.broad.mit.e... |
Broad ISOMERASE_ACTIVITY | View Gene Set | 0.001227 | 34 | 0.01104 | 41 | Genes annotated by the GO term GO:0016853. Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. | www.broad.mit.e... |
Broad ENDONUCLEASE_ACTIVITY_GO_0016893 | View Gene Set | 0.001199 | 11 | 0.01104 | 41 | Genes annotated by the GO term GO:0016893. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. | www.broad.mit.e... |
Broad NUCLEOTIDE_BINDING | View Gene Set | 0.001316 | 218 | 0.01158 | 45 | Genes annotated by the GO term GO:0000166. Interacting selectively with a nucleotide any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose moiety. | www.broad.mit.e... |
Broad PURINE_NUCLEOTIDE_BINDING | View Gene Set | 0.001494 | 205 | 0.01286 | 46 | Genes annotated by the GO term GO:0017076. Interacting selectively with purine nucleotides any compound consisting of a purine nucleoside esterified with (ortho)phosphate. | www.broad.mit.e... |
Broad NUCLEASE_ACTIVITY | View Gene Set | 0.001565 | 54 | 0.01318 | 47 | Genes annotated by the GO term GO:0004518. Catalysis of the hydrolysis of ester linkages within nucleic acids. | www.broad.mit.e... |
Broad RIBONUCLEOPROTEIN_BINDING | View Gene Set | 0.001747 | 9 | 0.01441 | 48 | Genes annotated by the GO term GO:0043021. Interacting selectively with any complex of RNA and protein. | www.broad.mit.e... |
Broad TRANSCRIPTION_COREPRESSOR_ACTIVITY | View Gene Set | 0.001826 | 91 | 0.01476 | 49 | Genes annotated by the GO term GO:0003714. The function of a transcription cofactor that represses transcription from a RNA polymerase II promoter; does not bind DNA itself. | www.broad.mit.e... |
Broad IDENTICAL_PROTEIN_BINDING | View Gene Set | 0.00193 | 300 | 0.01529 | 50 | Genes annotated by the GO term GO:0042802. Interacting selectively with an identical protein or proteins. | www.broad.mit.e... |
Broad ELECTRON_CARRIER_ACTIVITY | View Gene Set | 0.001984 | 76 | 0.0154 | 51 | Genes annotated by the GO term GO:0009055. Any molecular entity that serves as an electron acceptor and electron donor in an electron transport system. | www.broad.mit.e... |
Broad PURINE_RIBONUCLEOTIDE_BINDING | View Gene Set | 0.002142 | 200 | 0.01631 | 52 | Genes annotated by the GO term GO:0032555. Interacting selectively with a purine ribonucleotide any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. | www.broad.mit.e... |
Broad PROTEIN_TRANSPORTER_ACTIVITY | View Gene Set | 0.002539 | 14 | 0.0182 | 53 | Genes annotated by the GO term GO:0008565. Enables the directed movement of proteins into out of within or between cells. | www.broad.mit.e... |
Broad BETA_TUBULIN_BINDING | View Gene Set | 0.002501 | 10 | 0.0182 | 53 | Genes annotated by the GO term GO:0048487. Interacting selectively with the microtubule constituent protein beta-tubulin. | www.broad.mit.e... |
Broad CHAPERONE_BINDING | View Gene Set | 0.002573 | 12 | 0.0182 | 53 | Genes annotated by the GO term GO:0051087. Interacting selectively with a chaperone protein a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport. | www.broad.mit.e... |
Broad GUANYL_NUCLEOTIDE_BINDING | View Gene Set | 0.002448 | 47 | 0.0182 | 53 | Genes annotated by the GO term GO:0019001. Interacting selectively with guanyl nucleotides any compound consisting of guanosine esterified with (ortho)phosphate. | www.broad.mit.e... |
Broad GTP_BINDING | View Gene Set | 0.002944 | 46 | 0.02033 | 57 | Genes annotated by the GO term GO:0005525. Interacting selectively with GTP guanosine triphosphate. | www.broad.mit.e... |
Broad INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY | View Gene Set | 0.002978 | 18 | 0.02033 | 57 | Genes annotated by the GO term GO:0016860. Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule and no oxidized product appears. | www.broad.mit.e... |
Broad RIBONUCLEASE_ACTIVITY | View Gene Set | 0.003061 | 25 | 0.02054 | 59 | Genes annotated by the GO term GO:0004540. Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. | www.broad.mit.e... |
Broad PROTEIN_N_TERMINUS_BINDING | View Gene Set | 0.003347 | 38 | 0.02192 | 60 | Genes annotated by the GO term GO:0047485. Interacting selectively with a protein N-terminus the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue. | www.broad.mit.e... |
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_ALKYL_OR_ARYLOTHER_THAN_METHYLGROUPS | View Gene Set | 0.003376 | 30 | 0.02192 | 60 | Genes annotated by the GO term GO:0016765. Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor). | www.broad.mit.e... |
Broad 3_5_EXONUCLEASE_ACTIVITY | View Gene Set | 0.004319 | 12 | 0.02759 | 62 | Genes annotated by the GO term GO:0008408. Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. | www.broad.mit.e... |
Broad ACID_AMINO_ACID_LIGASE_ACTIVITY | View Gene Set | 0.004406 | 57 | 0.02769 | 63 | Genes annotated by the GO term GO:0016881. Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage usually in a nucleoside triphosphate. | www.broad.mit.e... |
Broad DNA_HELICASE_ACTIVITY | View Gene Set | 0.004613 | 24 | 0.02826 | 64 | Genes annotated by the GO term GO:0003678. Catalysis of the unwinding of a DNA duplex. | www.broad.mit.e... |
Broad ATP_DEPENDENT_DNA_HELICASE_ACTIVITY | View Gene Set | 0.004639 | 11 | 0.02826 | 64 | Genes annotated by the GO term GO:0004003. Catalysis of the reaction: ATP + H2O = ADP + phosphate driving the unwinding of the DNA helix. | www.broad.mit.e... |
Broad NUCLEOTIDYLTRANSFERASE_ACTIVITY | View Gene Set | 0.004786 | 47 | 0.02836 | 66 | Genes annotated by the GO term GO:0016779. Catalysis of the transfer of a nucleotidyl group to a reactant. | www.broad.mit.e... |
Broad NF_KAPPAB_BINDING | View Gene Set | 0.004799 | 11 | 0.02836 | 66 | Genes annotated by the GO term GO:0051059. Interacting selectively with NF-kappaB a transcription factor for eukaryotic RNA polymerase II promoters. | www.broad.mit.e... |
Broad HORMONE_RECEPTOR_BINDING | View Gene Set | 0.004962 | 29 | 0.0289 | 68 | Genes annotated by the GO term GO:0051427. Interacting selectively with a receptor for hormones. | www.broad.mit.e... |
Broad CYTOCHROME_C_OXIDASE_ACTIVITY | View Gene Set | 0.005098 | 13 | 0.02909 | 69 | Genes annotated by the GO term GO:0004129. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O. | www.broad.mit.e... |
Broad KINASE_ACTIVITY | View Gene Set | 0.005142 | 359 | 0.02909 | 69 | Genes annotated by the GO term GO:0016301. Catalysis of the transfer of a phosphate group usually from ATP to a substrate molecule. | www.broad.mit.e... |
Broad ZINC_ION_BINDING | View Gene Set | 0.005271 | 89 | 0.0294 | 71 | Genes annotated by the GO term GO:0008270. Interacting selectively with zinc (Zn) ions. | www.broad.mit.e... |
Broad DEOXYRIBONUCLEASE_ACTIVITY | View Gene Set | 0.005761 | 22 | 0.03168 | 72 | Genes annotated by the GO term GO:0004536. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. | www.broad.mit.e... |
Broad THYROID_HORMONE_RECEPTOR_BINDING | View Gene Set | 0.005913 | 17 | 0.03207 | 73 | Genes annotated by the GO term GO:0046966. Interacting selectively with a thyroid hormone receptor. | www.broad.mit.e... |
Broad RAS_GTPASE_BINDING | View Gene Set | 0.006268 | 24 | 0.03354 | 74 | Genes annotated by the GO term GO:0017016. Interacting selectively with any member of the Ras superfamily of monomeric GTPases. | www.broad.mit.e... |
Broad ENDONUCLEASE_ACTIVITY | View Gene Set | 0.006351 | 25 | 0.03354 | 74 | Genes annotated by the GO term GO:0004519. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. | www.broad.mit.e... |
Broad SMALL_PROTEIN_CONJUGATING_ENZYME_ACTIVITY | View Gene Set | 0.006743 | 52 | 0.03513 | 76 | Genes annotated by the GO term GO:0008639. Catalysis of the covalent attachment of small proteins such as ubiquitin or ubiquitin-like proteins to lysine residues on a target protein. This function may be performed alone or in conjunction with an E3 ubiquitin-like protein ligase. | www.broad.mit.e... |
Broad PROTEIN_PHOSPHATASE_BINDING | View Gene Set | 0.006927 | 9 | 0.03562 | 77 | Genes annotated by the GO term GO:0019903. Interacting selectively with any protein phosphatase. | www.broad.mit.e... |
Broad ENDODEOXYRIBONUCLEASE_ACTIVITY | View Gene Set | 0.008198 | 11 | 0.04109 | 78 | Genes annotated by the GO term GO:0004520. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. | www.broad.mit.e... |
Broad PROTEIN_C_TERMINUS_BINDING | View Gene Set | 0.00811 | 73 | 0.04109 | 78 | Genes annotated by the GO term GO:0008022. Interacting selectively with a protein C-terminus the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue. | www.broad.mit.e... |
Broad HISTONE_DEACETYLASE_BINDING | View Gene Set | 0.008624 | 8 | 0.04269 | 80 | Genes annotated by the GO term GO:0042826. Interacting selectively with the enzyme histone deacetylase. | www.broad.mit.e... |
Broad NUCLEAR_HORMONE_RECEPTOR_BINDING | View Gene Set | 0.00881 | 28 | 0.04307 | 81 | Genes annotated by the GO term GO:0035257. Interacting selectively with a nuclear hormone receptor a ligand-dependent receptor found in the nucleus of the cell. | www.broad.mit.e... |
Broad TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS | View Gene Set | 0.00923 | 76 | 0.04457 | 82 | Genes annotated by the GO term GO:0016758. Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). | www.broad.mit.e... |
Broad AMINOPEPTIDASE_ACTIVITY | View Gene Set | 0.01042 | 13 | 0.0497 | 83 | Genes annotated by the GO term GO:0004177. Catalysis of the hydrolysis of N-terminal amino acid residues from oligopeptides or polypeptides. | www.broad.mit.e... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
PMID 15635413 | View Gene Set | 3.739e-74 | 421 | 9.375e-71 | 1 | Nucleolar proteome dynamics. | www.ncbi.nlm.ni... |
PMID 17643375 | View Gene Set | 7.229e-51 | 391 | 9.062e-48 | 2 | Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. | www.ncbi.nlm.ni... |
PMID 15302935 | View Gene Set | 3.724e-48 | 773 | 3.112e-45 | 3 | Large-scale characterization of HeLa cell nuclear phosphoproteins. | www.ncbi.nlm.ni... |
PMID 11790298 | View Gene Set | 1.87e-46 | 208 | 1.172e-43 | 4 | Directed proteomic analysis of the human nucleolus. | www.ncbi.nlm.ni... |
PMID 11042152 | View Gene Set | 7.511e-42 | 315 | 3.766e-39 | 5 | Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. | www.ncbi.nlm.ni... |
PMID 16964243 | View Gene Set | 1.518e-41 | 504 | 6.343e-39 | 6 | A probability-based approach for high-throughput protein phosphorylation analysis and site localization. | www.ncbi.nlm.ni... |
PMID 15592455 | View Gene Set | 9.837e-32 | 317 | 3.523e-29 | 7 | Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. | www.ncbi.nlm.ni... |
PMID 15189156 | View Gene Set | 3.378e-27 | 88 | 1.058e-24 | 8 | The molecular mechanics of eukaryotic translation. | www.ncbi.nlm.ni... |
PMID 15231747 | View Gene Set | 4.755e-27 | 212 | 1.324e-24 | 9 | A protein interaction framework for human mRNA degradation. | www.ncbi.nlm.ni... |
PMID 8722009 | View Gene Set | 4.708e-26 | 80 | 1.18e-23 | 10 | Structure and evolution of mammalian ribosomal proteins. | www.ncbi.nlm.ni... |
PMID 16565220 | View Gene Set | 4.069e-25 | 210 | 9.274e-23 | 11 | Phosphoproteome analysis of the human mitotic spindle. | www.ncbi.nlm.ni... |
PMID 12226669 | View Gene Set | 3.976e-24 | 108 | 8.307e-22 | 12 | Comprehensive proteomic analysis of the human spliceosome. | www.ncbi.nlm.ni... |
PMID 17220478 | View Gene Set | 9.748e-24 | 63 | 1.88e-21 | 13 | Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells. | www.ncbi.nlm.ni... |
PMID 10810093 | View Gene Set | 5.857e-23 | 151 | 1.049e-20 | 14 | Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. | www.ncbi.nlm.ni... |
PMID 9582194 | View Gene Set | 6.813e-22 | 67 | 1.139e-19 | 15 | A map of 75 human ribosomal protein genes. | www.ncbi.nlm.ni... |
PMID 12665801 | View Gene Set | 8.294e-22 | 261 | 1.3e-19 | 16 | Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. | www.ncbi.nlm.ni... |
PMID 16236267 | View Gene Set | 6.149e-21 | 77 | 9.068e-19 | 17 | Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. | www.ncbi.nlm.ni... |
PMID 12588972 | View Gene Set | 3.331e-18 | 56 | 4.64e-16 | 18 | Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region. | www.ncbi.nlm.ni... |
PMID 12706105 | View Gene Set | 7.299e-18 | 182 | 9.631e-16 | 19 | Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. | www.ncbi.nlm.ni... |
PMID 14559993 | View Gene Set | 1.304e-16 | 51 | 1.635e-14 | 20 | Regulation of alternative splicing by SRrp86 and its interacting proteins. | www.ncbi.nlm.ni... |
PMID 14567916 | View Gene Set | 2.639e-16 | 50 | 3.15e-14 | 21 | Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. | www.ncbi.nlm.ni... |
PMID 15231748 | View Gene Set | 2.774e-16 | 519 | 3.161e-14 | 22 | Functional proteomics mapping of a human signaling pathway. | www.ncbi.nlm.ni... |
PMID 7821789 | View Gene Set | 1.01e-14 | 59 | 1.101e-12 | 23 | Construction of a human full-length cDNA bank. | www.ncbi.nlm.ni... |
PMID 16341674 | View Gene Set | 1.902e-14 | 392 | 1.986e-12 | 24 | Transcriptome analysis of human gastric cancer. | www.ncbi.nlm.ni... |
PMID 11543634 | View Gene Set | 3.663e-14 | 58 | 3.673e-12 | 25 | The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. | www.ncbi.nlm.ni... |
PMID 12429849 | View Gene Set | 4.514e-14 | 106 | 4.352e-12 | 26 | Functional proteomic analysis of human nucleolus. | www.ncbi.nlm.ni... |
PMID 16130169 | View Gene Set | 6.455e-14 | 74 | 5.994e-12 | 27 | Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis. | www.ncbi.nlm.ni... |
PMID 15324660 | View Gene Set | 1.062e-13 | 242 | 9.512e-12 | 28 | Proteomic functional and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. | www.ncbi.nlm.ni... |
PMID 11875025 | View Gene Set | 2.458e-13 | 41 | 2.125e-11 | 29 | The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. | www.ncbi.nlm.ni... |
PMID 14667819 | View Gene Set | 5.557e-13 | 112 | 4.644e-11 | 30 | Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. | www.ncbi.nlm.ni... |
PMID 15489336 | View Gene Set | 1.037e-12 | 722 | 8.385e-11 | 31 | From ORFeome to biology: a functional genomics pipeline. | www.ncbi.nlm.ni... |
PMID 11991638 | View Gene Set | 1.695e-12 | 74 | 1.328e-10 | 32 | Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. | www.ncbi.nlm.ni... |
PMID 16381901 | View Gene Set | 1.877e-12 | 720 | 1.426e-10 | 33 | The LIFEdb database in 2006. | www.ncbi.nlm.ni... |
PMID 15782174 | View Gene Set | 3.011e-12 | 31 | 2.22e-10 | 34 | Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. | www.ncbi.nlm.ni... |
PMID 10931946 | View Gene Set | 3.838e-12 | 118 | 2.749e-10 | 35 | Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. | www.ncbi.nlm.ni... |
PMID 20085707 | View Gene Set | 4.083e-12 | 42 | 2.843e-10 | 36 | Aire's partners in the molecular control of immunological tolerance. | www.ncbi.nlm.ni... |
PMID 19710015 | View Gene Set | 4.313e-12 | 48 | 2.922e-10 | 37 | The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor. | www.ncbi.nlm.ni... |
PMID 11256614 | View Gene Set | 7.391e-12 | 522 | 4.876e-10 | 38 | Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. | www.ncbi.nlm.ni... |
PMID 11285280 | View Gene Set | 8.111e-12 | 62 | 5.214e-10 | 39 | Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. | www.ncbi.nlm.ni... |
PMID 15952740 | View Gene Set | 1.009e-11 | 58 | 6.323e-10 | 40 | Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry. | www.ncbi.nlm.ni... |
PMID 17081065 | View Gene Set | 2.376e-11 | 80 | 1.453e-09 | 41 | Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. | www.ncbi.nlm.ni... |
PMID 19064571 | View Gene Set | 4.331e-11 | 75 | 2.585e-09 | 42 | Polymorphisms in mitochondrial genes and prostate cancer risk. | www.ncbi.nlm.ni... |
PMID 14743216 | View Gene Set | 1.085e-10 | 132 | 6.324e-09 | 43 | A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. | www.ncbi.nlm.ni... |
PMID 16303743 | View Gene Set | 1.763e-10 | 427 | 1.005e-08 | 44 | Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. | www.ncbi.nlm.ni... |
PMID 11401437 | View Gene Set | 3.517e-10 | 27 | 1.96e-08 | 45 | A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders. | www.ncbi.nlm.ni... |
PMID 15883184 | View Gene Set | 4.924e-10 | 31 | 2.684e-08 | 46 | Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes. | www.ncbi.nlm.ni... |
PMID 17289661 | View Gene Set | 5.355e-10 | 35 | 2.856e-08 | 47 | Molecular composition of IMP1 ribonucleoprotein granules. | www.ncbi.nlm.ni... |
PMID 8706699 | View Gene Set | 5.734e-10 | 35 | 2.995e-08 | 48 | Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing and mass spectrometry. | www.ncbi.nlm.ni... |
PMID 12388589 | View Gene Set | 1.014e-09 | 17 | 5.189e-08 | 49 | A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. | www.ncbi.nlm.ni... |
PMID 8619474 | View Gene Set | 1.263e-09 | 534 | 6.332e-08 | 50 | A "double adaptor" method for improved shotgun library construction. | www.ncbi.nlm.ni... |
PMID 17148452 | View Gene Set | 1.389e-09 | 87 | 6.828e-08 | 51 | Characterization of the interactome of the human MutL homologues MLH1 PMS1 and PMS2. | www.ncbi.nlm.ni... |
PMID 9110174 | View Gene Set | 1.528e-09 | 528 | 7.368e-08 | 52 | Large-scale concatenation cDNA sequencing. | www.ncbi.nlm.ni... |
PMID 11101529 | View Gene Set | 1.831e-09 | 34 | 8.659e-08 | 53 | Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. | www.ncbi.nlm.ni... |
PMID 9653160 | View Gene Set | 2.806e-09 | 36 | 1.303e-07 | 54 | Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning. | www.ncbi.nlm.ni... |
PMID 12962325 | View Gene Set | 3.152e-09 | 22 | 1.437e-07 | 55 | Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. | www.ncbi.nlm.ni... |
PMID 18377426 | View Gene Set | 3.705e-09 | 20 | 1.659e-07 | 56 | Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex. | www.ncbi.nlm.ni... |
PMID 20508983 | View Gene Set | 4.148e-09 | 102 | 1.825e-07 | 57 | Centrosome-related genes genetic variation and risk of breast cancer. | www.ncbi.nlm.ni... |
PMID 1602151 | View Gene Set | 4.38e-09 | 99 | 1.893e-07 | 58 | Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. | www.ncbi.nlm.ni... |
PMID 12791267 | View Gene Set | 5.45e-09 | 50 | 2.316e-07 | 59 | Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. | www.ncbi.nlm.ni... |
PMID 15029244 | View Gene Set | 5.653e-09 | 57 | 2.362e-07 | 60 | Mammalian Cdh1/Fzr mediates its own degradation. | www.ncbi.nlm.ni... |
PMID 18809582 | View Gene Set | 8.586e-09 | 25 | 3.529e-07 | 61 | Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. | www.ncbi.nlm.ni... |
PMID 12234937 | View Gene Set | 1.714e-08 | 34 | 6.932e-07 | 62 | Characterization of novel SF3b and 17S U2 snRNP proteins including a human Prp5p homologue and an SF3b DEAD-box protein. | www.ncbi.nlm.ni... |
PMID 11230166 | View Gene Set | 1.883e-08 | 748 | 7.495e-07 | 63 | Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. | www.ncbi.nlm.ni... |
PMID 15456888 | View Gene Set | 2.164e-08 | 24 | 8.478e-07 | 64 | The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. | www.ncbi.nlm.ni... |
PMID 15146197 | View Gene Set | 2.918e-08 | 693 | 1.126e-06 | 65 | Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. | www.ncbi.nlm.ni... |
PMID 14564014 | View Gene Set | 3.023e-08 | 47 | 1.148e-06 | 66 | Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. | www.ncbi.nlm.ni... |
PMID 11279123 | View Gene Set | 5.799e-08 | 31 | 2.141e-06 | 67 | The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. | www.ncbi.nlm.ni... |
PMID 1286669 | View Gene Set | 5.806e-08 | 28 | 2.141e-06 | 67 | Human liver protein map: a reference database established by microsequencing and gel comparison. | www.ncbi.nlm.ni... |
PMID 18162579 | View Gene Set | 6.242e-08 | 22 | 2.268e-06 | 69 | Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. | www.ncbi.nlm.ni... |
PMID 10893419 | View Gene Set | 9.573e-08 | 41 | 3.288e-06 | 70 | Degradation of HIV-1 integrase by the N-end rule pathway. | www.ncbi.nlm.ni... |
PMID 12419264 | View Gene Set | 9.573e-08 | 41 | 3.288e-06 | 70 | The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing. | www.ncbi.nlm.ni... |
PMID 14550573 | View Gene Set | 9.573e-08 | 41 | 3.288e-06 | 70 | Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits. | www.ncbi.nlm.ni... |
PMID 9079628 | View Gene Set | 9.573e-08 | 41 | 3.288e-06 | 70 | HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation. | www.ncbi.nlm.ni... |
PMID 11076863 | View Gene Set | 1.275e-07 | 794 | 4.319e-06 | 74 | DNA cloning using in vitro site-specific recombination. | www.ncbi.nlm.ni... |
PMID 12719574 | View Gene Set | 1.834e-07 | 42 | 5.541e-06 | 75 | Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions. | www.ncbi.nlm.ni... |
PMID 12750511 | View Gene Set | 1.834e-07 | 42 | 5.541e-06 | 75 | Hypermutation of HIV-1 DNA in the absence of the Vif protein. | www.ncbi.nlm.ni... |
PMID 12830140 | View Gene Set | 1.834e-07 | 42 | 5.541e-06 | 75 | DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses. | www.ncbi.nlm.ni... |
PMID 12840737 | View Gene Set | 1.834e-07 | 42 | 5.541e-06 | 75 | Good to CU. | www.ncbi.nlm.ni... |
PMID 12914693 | View Gene Set | 1.834e-07 | 42 | 5.541e-06 | 75 | Death by deamination: a novel host restriction system for HIV-1. | www.ncbi.nlm.ni... |
PMID 12920286 | View Gene Set | 1.834e-07 | 42 | 5.541e-06 | 75 | Virology. Weapons of mutational destruction. | www.ncbi.nlm.ni... |
PMID 14614829 | View Gene Set | 1.834e-07 | 42 | 5.541e-06 | 75 | The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G. | www.ncbi.nlm.ni... |
PMID 9811770 | View Gene Set | 1.834e-07 | 42 | 5.541e-06 | 75 | An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein. | www.ncbi.nlm.ni... |
PMID 9846577 | View Gene Set | 1.834e-07 | 42 | 5.541e-06 | 75 | Evidence for a newly discovered cellular anti-HIV-1 phenotype. | www.ncbi.nlm.ni... |
PMID 12167863 | View Gene Set | 2.162e-07 | 43 | 5.832e-06 | 84 | Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. | www.ncbi.nlm.ni... |
PMID 12808465 | View Gene Set | 2.162e-07 | 43 | 5.832e-06 | 84 | The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. | www.ncbi.nlm.ni... |
PMID 12808466 | View Gene Set | 2.162e-07 | 43 | 5.832e-06 | 84 | Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. | www.ncbi.nlm.ni... |
PMID 12809610 | View Gene Set | 2.162e-07 | 43 | 5.832e-06 | 84 | DNA deamination mediates innate immunity to retroviral infection. | www.ncbi.nlm.ni... |
PMID 12970355 | View Gene Set | 2.162e-07 | 43 | 5.832e-06 | 84 | The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity. | www.ncbi.nlm.ni... |
PMID 14527406 | View Gene Set | 2.162e-07 | 43 | 5.832e-06 | 84 | HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. | www.ncbi.nlm.ni... |
PMID 14528300 | View Gene Set | 2.162e-07 | 43 | 5.832e-06 | 84 | The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. | www.ncbi.nlm.ni... |
PMID 14528301 | View Gene Set | 2.162e-07 | 43 | 5.832e-06 | 84 | HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. | www.ncbi.nlm.ni... |
PMID 14557625 | View Gene Set | 2.162e-07 | 43 | 5.832e-06 | 84 | The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15) a cellular inhibitor of virus infectivity. | www.ncbi.nlm.ni... |
PMID 16085932 | View Gene Set | 2.163e-07 | 18 | 5.832e-06 | 84 | A novel evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. | www.ncbi.nlm.ni... |
PMID 16713569 | View Gene Set | 3.901e-07 | 570 | 1.041e-05 | 94 | A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. | www.ncbi.nlm.ni... |
PMID 7584044 | View Gene Set | 3.981e-07 | 41 | 1.051e-05 | 95 | Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. | www.ncbi.nlm.ni... |
PMID 12493763 | View Gene Set | 6.373e-07 | 18 | 1.664e-05 | 96 | A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes. | www.ncbi.nlm.ni... |
PMID 12228227 | View Gene Set | 7.122e-07 | 30 | 1.841e-05 | 97 | Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1. | www.ncbi.nlm.ni... |
PMID 19237606 | View Gene Set | 7.266e-07 | 84 | 1.859e-05 | 98 | Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. | www.ncbi.nlm.ni... |
PMID 19738611 | View Gene Set | 7.424e-07 | 39 | 1.88e-05 | 99 | Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis. | www.ncbi.nlm.ni... |
PMID 11551941 | View Gene Set | 7.976e-07 | 26 | 2e-05 | 100 | The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. | www.ncbi.nlm.ni... |
PMID 7788527 | View Gene Set | 9.059e-07 | 42 | 2.249e-05 | 101 | Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. | www.ncbi.nlm.ni... |
PMID 8811196 | View Gene Set | 1.048e-06 | 37 | 2.575e-05 | 102 | Structure and functions of the 20S and 26S proteasomes. | www.ncbi.nlm.ni... |
PMID 19019082 | View Gene Set | 1.112e-06 | 49 | 2.706e-05 | 103 | Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes. | www.ncbi.nlm.ni... |
PMID 18063578 | View Gene Set | 1.127e-06 | 31 | 2.718e-05 | 104 | The layered structure of human mitochondrial DNA nucleoids. | www.ncbi.nlm.ni... |
PMID 17540176 | View Gene Set | 1.15e-06 | 28 | 2.745e-05 | 105 | The tumor suppressor PP2A Abeta regulates the RalA GTPase. | www.ncbi.nlm.ni... |
PMID 15835887 | View Gene Set | 1.233e-06 | 12 | 2.916e-05 | 106 | Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61 TRAP and two potential new subunits. | www.ncbi.nlm.ni... |
PMID 16097034 | View Gene Set | 1.369e-06 | 36 | 3.178e-05 | 107 | Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC. | www.ncbi.nlm.ni... |
PMID 16730941 | View Gene Set | 1.368e-06 | 55 | 3.178e-05 | 107 | A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex. | www.ncbi.nlm.ni... |
PMID 10942595 | View Gene Set | 1.416e-06 | 25 | 3.257e-05 | 109 | A visual intracellular classification strategy for uncharacterized human proteins. | www.ncbi.nlm.ni... |
PMID 12171929 | View Gene Set | 1.511e-06 | 31 | 3.443e-05 | 110 | A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. | www.ncbi.nlm.ni... |
PMID 11031247 | View Gene Set | 1.56e-06 | 51 | 3.519e-05 | 111 | Secretory protein trafficking and organelle dynamics in living cells. | www.ncbi.nlm.ni... |
PMID 11829477 | View Gene Set | 1.572e-06 | 13 | 3.519e-05 | 111 | Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex. | www.ncbi.nlm.ni... |
PMID 17274640 | View Gene Set | 1.587e-06 | 30 | 3.521e-05 | 113 | A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis. | www.ncbi.nlm.ni... |
PMID 9731529 | View Gene Set | 1.848e-06 | 24 | 4.065e-05 | 114 | Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. | www.ncbi.nlm.ni... |
PMID 11013263 | View Gene Set | 1.909e-06 | 16 | 4.162e-05 | 115 | A novel nuclear receptor corepressor complex N-CoR contains components of the mammalian SWI/SNF complex and the corepressor KAP-1. | www.ncbi.nlm.ni... |
PMID 12754519 | View Gene Set | 1.949e-06 | 71 | 4.213e-05 | 116 | Identification and quantification of N-linked glycoproteins using hydrazide chemistry stable isotope labeling and mass spectrometry. | www.ncbi.nlm.ni... |
PMID 12859895 | View Gene Set | 1.984e-06 | 47 | 4.25e-05 | 117 | Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. | www.ncbi.nlm.ni... |
PMID 11748230 | View Gene Set | 2.336e-06 | 17 | 4.928e-05 | 118 | Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. | www.ncbi.nlm.ni... |
PMID 9878551 | View Gene Set | 2.339e-06 | 34 | 4.928e-05 | 118 | cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. | www.ncbi.nlm.ni... |
PMID 20516191 | View Gene Set | 2.618e-06 | 12 | 5.469e-05 | 120 | A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins). | www.ncbi.nlm.ni... |
PMID 10725331 | View Gene Set | 2.758e-06 | 14 | 5.714e-05 | 121 | Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. | www.ncbi.nlm.ni... |
PMID 14729942 | View Gene Set | 2.831e-06 | 18 | 5.818e-05 | 122 | Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line. | www.ncbi.nlm.ni... |
PMID 20496165 | View Gene Set | 2.947e-06 | 68 | 6.006e-05 | 123 | Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. | www.ncbi.nlm.ni... |
PMID 18697920 | View Gene Set | 3.195e-06 | 14 | 6.459e-05 | 124 | The role of human ribosomal proteins in the maturation of rRNA and ribosome production. | www.ncbi.nlm.ni... |
PMID 15383276 | View Gene Set | 3.268e-06 | 67 | 6.554e-05 | 125 | A protein interaction network links GIT1 an enhancer of huntingtin aggregation to Huntington's disease. | www.ncbi.nlm.ni... |
PMID 9150948 | View Gene Set | 3.503e-06 | 15 | 6.97e-05 | 126 | A two-dimensional gel database of human colon carcinoma proteins. | www.ncbi.nlm.ni... |
PMID 15130578 | View Gene Set | 3.865e-06 | 22 | 7.629e-05 | 127 | Why do cells need an assembly machine for RNA-protein complexes? | www.ncbi.nlm.ni... |
PMID 12761501 | View Gene Set | 4.082e-06 | 94 | 7.995e-05 | 128 | Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. | www.ncbi.nlm.ni... |
PMID 18715871 | View Gene Set | 4.368e-06 | 20 | 8.489e-05 | 129 | PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4. | www.ncbi.nlm.ni... |
PMID 15232106 | View Gene Set | 4.523e-06 | 30 | 8.722e-05 | 130 | Self-assembling protein microarrays. | www.ncbi.nlm.ni... |
PMID 8076819 | View Gene Set | 5.139e-06 | 37 | 9.834e-05 | 131 | The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression. | www.ncbi.nlm.ni... |
PMID 10766737 | View Gene Set | 6.583e-06 | 11 | 0.0001215 | 132 | Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. | www.ncbi.nlm.ni... |
PMID 11714285 | View Gene Set | 6.785e-06 | 11 | 0.0001215 | 132 | The appended C-domain of human methionyl-tRNA synthetase has a tRNA-sequestering function. | www.ncbi.nlm.ni... |
PMID 1286667 | View Gene Set | 6.425e-06 | 45 | 0.0001215 | 132 | Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. | www.ncbi.nlm.ni... |
PMID 15009096 | View Gene Set | 6.832e-06 | 39 | 0.0001215 | 132 | Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex while BMI-1 is transiently co-localized with the centromeric region in interphase. | www.ncbi.nlm.ni... |
PMID 16055448 | View Gene Set | 6.785e-06 | 11 | 0.0001215 | 132 | The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex. | www.ncbi.nlm.ni... |
PMID 8052601 | View Gene Set | 6.785e-06 | 11 | 0.0001215 | 132 | Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit. | www.ncbi.nlm.ni... |
PMID 8078941 | View Gene Set | 6.785e-06 | 11 | 0.0001215 | 132 | Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer. | www.ncbi.nlm.ni... |
PMID 8188258 | View Gene Set | 6.785e-06 | 11 | 0.0001215 | 132 | The human EPRS locus (formerly the QARS locus): a gene encoding a class I and a class II aminoacyl-tRNA synthetase. | www.ncbi.nlm.ni... |
PMID 8449960 | View Gene Set | 6.785e-06 | 11 | 0.0001215 | 132 | Expression of human aspartyl-tRNA synthetase in Escherichia coli. Functional analysis of the N-terminal putative amphiphilic helix. | www.ncbi.nlm.ni... |
PMID 9278442 | View Gene Set | 6.785e-06 | 11 | 0.0001215 | 132 | Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant. | www.ncbi.nlm.ni... |
PMID 15308636 | View Gene Set | 7.117e-06 | 25 | 0.0001256 | 142 | Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32 a new cycling protein that interacts with human Erv46. | www.ncbi.nlm.ni... |
PMID 15146077 | View Gene Set | 7.433e-06 | 32 | 0.0001292 | 143 | The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. | www.ncbi.nlm.ni... |
PMID 16094384 | View Gene Set | 7.393e-06 | 80 | 0.0001292 | 143 | Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. | www.ncbi.nlm.ni... |
PMID 18954305 | View Gene Set | 7.472e-06 | 13 | 0.0001292 | 143 | Structural basis and specificity of human otubain 1-mediated deubiquitination. | www.ncbi.nlm.ni... |
PMID 11713266 | View Gene Set | 7.618e-06 | 12 | 0.0001308 | 146 | The methylosome a 20S complex containing JBP1 and pICln produces dimethylarginine-modified Sm proteins. | www.ncbi.nlm.ni... |
PMID 15504738 | View Gene Set | 9.031e-06 | 19 | 0.000154 | 147 | Genes affecting the cell cycle growth maintenance and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. | www.ncbi.nlm.ni... |
PMID 11252894 | View Gene Set | 9.244e-06 | 44 | 0.0001565 | 148 | Three ways to make a vesicle. | www.ncbi.nlm.ni... |
PMID 12611891 | View Gene Set | 9.303e-06 | 40 | 0.0001565 | 148 | The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. | www.ncbi.nlm.ni... |
PMID 12791985 | View Gene Set | 1.008e-05 | 37 | 0.0001685 | 150 | Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. | www.ncbi.nlm.ni... |
PMID 7584026 | View Gene Set | 1.071e-05 | 43 | 0.0001778 | 151 | Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. | www.ncbi.nlm.ni... |
PMID 19596235 | View Gene Set | 1.078e-05 | 85 | 0.0001778 | 152 | Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. | www.ncbi.nlm.ni... |
PMID 19536092 | View Gene Set | 1.299e-05 | 55 | 0.0002129 | 153 | Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array. | www.ncbi.nlm.ni... |
PMID 10601333 | View Gene Set | 1.377e-05 | 12 | 0.0002242 | 154 | Gemin3: A novel DEAD box protein that interacts with SMN the spinal muscular atrophy gene product and is a component of gems. | www.ncbi.nlm.ni... |
PMID 20522537 | View Gene Set | 1.446e-05 | 73 | 0.0002339 | 155 | Variation within DNA repair pathway genes and risk of multiple sclerosis. | www.ncbi.nlm.ni... |
PMID 20381070 | View Gene Set | 1.63e-05 | 40 | 0.0002619 | 156 | Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. | www.ncbi.nlm.ni... |
PMID 10851237 | View Gene Set | 1.912e-05 | 11 | 0.0003053 | 157 | Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). | www.ncbi.nlm.ni... |
PMID 12620389 | View Gene Set | 2.096e-05 | 23 | 0.0003326 | 158 | Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis. | www.ncbi.nlm.ni... |
PMID 9804427 | View Gene Set | 2.163e-05 | 14 | 0.000341 | 159 | Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex. | www.ncbi.nlm.ni... |
PMID 12670868 | View Gene Set | 2.227e-05 | 21 | 0.000349 | 160 | Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. | www.ncbi.nlm.ni... |
PMID 15761153 | View Gene Set | 2.247e-05 | 211 | 0.0003499 | 161 | High-throughput mapping of a dynamic signaling network in mammalian cells. | www.ncbi.nlm.ni... |
PMID 12481031 | View Gene Set | 2.27e-05 | 21 | 0.0003513 | 162 | CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex. | www.ncbi.nlm.ni... |
PMID 16916647 | View Gene Set | 2.345e-05 | 76 | 0.0003607 | 163 | Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. | www.ncbi.nlm.ni... |
PMID 11931757 | View Gene Set | 2.445e-05 | 22 | 0.0003699 | 164 | Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. | www.ncbi.nlm.ni... |
PMID 15647280 | View Gene Set | 2.45e-05 | 17 | 0.0003699 | 164 | The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. | www.ncbi.nlm.ni... |
PMID 16582619 | View Gene Set | 2.445e-05 | 15 | 0.0003699 | 164 | Identification of novel ARF binding proteins by two-hybrid screening. | www.ncbi.nlm.ni... |
PMID 16964240 | View Gene Set | 2.737e-05 | 32 | 0.0004106 | 167 | Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. | www.ncbi.nlm.ni... |
PMID 18782753 | View Gene Set | 2.752e-05 | 45 | 0.0004106 | 167 | A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. | www.ncbi.nlm.ni... |
PMID 9763677 | View Gene Set | 2.801e-05 | 15 | 0.0004156 | 169 | Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. | www.ncbi.nlm.ni... |
PMID 17601350 | View Gene Set | 2.894e-05 | 119 | 0.0004268 | 170 | A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. | www.ncbi.nlm.ni... |
PMID 9891079 | View Gene Set | 3.095e-05 | 15 | 0.0004537 | 171 | Cyclin E associates with BAF155 and BRG1 components of the mammalian SWI-SNF complex and alters the ability of BRG1 to induce growth arrest. | www.ncbi.nlm.ni... |
PMID 15644312 | View Gene Set | 3.301e-05 | 10 | 0.0004812 | 172 | Dissection of the mitochondrial import and assembly pathway for human Tom40. | www.ncbi.nlm.ni... |
PMID 8662825 | View Gene Set | 3.378e-05 | 10 | 0.0004895 | 173 | Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage. | www.ncbi.nlm.ni... |
PMID 11310559 | View Gene Set | 3.528e-05 | 17 | 0.0005083 | 174 | Identification of nuclear-import and cell-cycle regulatory proteins that bind to prothymosin alpha. | www.ncbi.nlm.ni... |
PMID 9121429 | View Gene Set | 3.655e-05 | 39 | 0.0005236 | 175 | The human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzyme. | www.ncbi.nlm.ni... |
PMID 10531003 | View Gene Set | 3.885e-05 | 15 | 0.0005534 | 176 | Newly assembled snRNPs associate with coiled bodies before speckles suggesting a nuclear snRNP maturation pathway. | www.ncbi.nlm.ni... |
PMID 14966270 | View Gene Set | 3.936e-05 | 19 | 0.0005575 | 177 | Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. | www.ncbi.nlm.ni... |
PMID 11714716 | View Gene Set | 4.004e-05 | 13 | 0.0005639 | 178 | Gemin5 a novel WD repeat protein component of the SMN complex that binds Sm proteins. | www.ncbi.nlm.ni... |
PMID 12393188 | View Gene Set | 4.075e-05 | 15 | 0.0005707 | 179 | Ku antigen an origin-specific binding protein that associates with replication proteins is required for mammalian DNA replication. | www.ncbi.nlm.ni... |
PMID 12840015 | View Gene Set | 4.153e-05 | 12 | 0.0005785 | 180 | Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing. | www.ncbi.nlm.ni... |
PMID 15949438 | View Gene Set | 4.478e-05 | 11 | 0.0006202 | 181 | Binding of pRB to the PHD protein RBP2 promotes cellular differentiation. | www.ncbi.nlm.ni... |
PMID 11205743 | View Gene Set | 4.58e-05 | 15 | 0.0006309 | 182 | Polo-like kinase interacts with proteasomes and regulates their activity. | www.ncbi.nlm.ni... |
PMID 11531413 | View Gene Set | 4.608e-05 | 27 | 0.0006313 | 183 | HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25. | www.ncbi.nlm.ni... |
PMID 15142377 | View Gene Set | 5.018e-05 | 19 | 0.0006837 | 184 | Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1. | www.ncbi.nlm.ni... |
PMID 9822659 | View Gene Set | 5.276e-05 | 11 | 0.000715 | 185 | Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3. | www.ncbi.nlm.ni... |
PMID 9472028 | View Gene Set | 5.493e-05 | 12 | 0.0007404 | 186 | SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. | www.ncbi.nlm.ni... |
PMID 11095689 | View Gene Set | 5.688e-05 | 17 | 0.0007626 | 187 | The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase. | www.ncbi.nlm.ni... |
PMID 15707391 | View Gene Set | 6.071e-05 | 23 | 0.0008096 | 188 | DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. | www.ncbi.nlm.ni... |
PMID 12837248 | View Gene Set | 6.195e-05 | 22 | 0.0008217 | 189 | The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. | www.ncbi.nlm.ni... |
PMID 17322308 | View Gene Set | 6.284e-05 | 13 | 0.0008248 | 190 | Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry. | www.ncbi.nlm.ni... |
PMID 18599441 | View Gene Set | 6.284e-05 | 13 | 0.0008248 | 190 | Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3. | www.ncbi.nlm.ni... |
PMID 9878398 | View Gene Set | 6.914e-05 | 13 | 0.0009028 | 192 | Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. | www.ncbi.nlm.ni... |
PMID 9039502 | View Gene Set | 7.061e-05 | 84 | 0.0009172 | 193 | Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. | www.ncbi.nlm.ni... |
PMID 18950845 | View Gene Set | 7.253e-05 | 88 | 0.0009373 | 194 | Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. | www.ncbi.nlm.ni... |
PMID 16712791 | View Gene Set | 8.038e-05 | 342 | 0.001033 | 195 | Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. | www.ncbi.nlm.ni... |
PMID 19183483 | View Gene Set | 8.508e-05 | 17 | 0.001088 | 196 | Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort. | www.ncbi.nlm.ni... |
PMID 11742988 | View Gene Set | 8.777e-05 | 20 | 0.001117 | 197 | APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box. | www.ncbi.nlm.ni... |
PMID 11279069 | View Gene Set | 8.828e-05 | 15 | 0.001118 | 198 | Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. | www.ncbi.nlm.ni... |
PMID 11102443 | View Gene Set | 9.17e-05 | 14 | 0.001154 | 199 | Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1. | www.ncbi.nlm.ni... |
PMID 15265780 | View Gene Set | 9.202e-05 | 14 | 0.001154 | 199 | Human immunodeficiency virus type-1 accessory protein Vpr: a causative agent of the AIDS-related insulin resistance/lipodystrophy syndrome? | www.ncbi.nlm.ni... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null chr22_37.5-42.5Mb | View Gene Set | 1.235e-06 | 59 | 0.001375 | 1 | Genomic tile: chr22 ; 37500001-42500001 Mb | genome.ucsc.edu... |
Null chr1_220-225Mb | View Gene Set | 6.979e-06 | 28 | 0.003888 | 2 | Genomic tile: chr1 ; 220000001-225000001 Mb | genome.ucsc.edu... |
Null chr5_67.5-72.5Mb | View Gene Set | 1.601e-05 | 16 | 0.005947 | 3 | Genomic tile: chr5 ; 67500001-72500001 Mb | genome.ucsc.edu... |
Null chr1_217.5-222.5Mb | View Gene Set | 3.596e-05 | 15 | 0.01001 | 4 | Genomic tile: chr1 ; 217500001-222500001 Mb | genome.ucsc.edu... |
Null chr1_42.5-47.5Mb | View Gene Set | 6.571e-05 | 68 | 0.01464 | 5 | Genomic tile: chr1 ; 42500001-47500001 Mb | genome.ucsc.edu... |
Null chr11_60-65Mb | View Gene Set | 9.936e-05 | 104 | 0.01845 | 6 | Genomic tile: chr11 ; 60000001-65000001 Mb | genome.ucsc.edu... |
Null chr22_40-45Mb | View Gene Set | 0.0001169 | 51 | 0.01861 | 7 | Genomic tile: chr22 ; 40000001-45000001 Mb | genome.ucsc.edu... |
Null chr14_17.5-22.5Mb | View Gene Set | 0.0001873 | 50 | 0.01899 | 8 | Genomic tile: chr14 ; 17500001-22500001 Mb | genome.ucsc.edu... |
Null chr16_42.5-47.5Mb | View Gene Set | 0.0001416 | 8 | 0.01899 | 8 | Genomic tile: chr16 ; 42500001-47500001 Mb | genome.ucsc.edu... |
Null chr17_2.5-7.5Mb | View Gene Set | 0.0001875 | 77 | 0.01899 | 8 | Genomic tile: chr17 ; 2500001-7500001 Mb | genome.ucsc.edu... |
Null chr17_5-10Mb | View Gene Set | 0.0001593 | 90 | 0.01899 | 8 | Genomic tile: chr17 ; 5000001-10000001 Mb | genome.ucsc.edu... |
Null chr3_45-50Mb | View Gene Set | 0.0002179 | 72 | 0.02023 | 12 | Genomic tile: chr3 ; 45000001-50000001 Mb | genome.ucsc.edu... |
Null chr19_35-40Mb | View Gene Set | 0.0005537 | 25 | 0.04745 | 13 | Genomic tile: chr19 ; 35000001-40000001 Mb | genome.ucsc.edu... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null PS50102 | View Gene Set | 1.316e-18 | 229 | 9.676e-16 | 1 | RRM | expasy.org/pros... |
Null PS50127 | View Gene Set | 2.429e-08 | 41 | 8.925e-06 | 2 | UBIQUITIN_CONJUGAT_2 | expasy.org/pros... |
Null PS00183 | View Gene Set | 2.889e-06 | 25 | 0.0006499 | 3 | UBIQUITIN_CONJUGAT_1 | expasy.org/pros... |
Null PS51192 | View Gene Set | 3.537e-06 | 112 | 0.0006499 | 3 | HELICASE_ATP_BIND_1 | expasy.org/pros... |
Null PS51352 | View Gene Set | 5.804e-06 | 36 | 0.0008531 | 5 | THIOREDOXIN_2 | expasy.org/pros... |
Null PS51194 | View Gene Set | 7.158e-06 | 113 | 0.0008768 | 6 | HELICASE_CTER | expasy.org/pros... |
Null PS00194 | View Gene Set | 1.108e-05 | 17 | 0.001164 | 7 | THIOREDOXIN_1 | expasy.org/pros... |
Null PS51195 | View Gene Set | 1.327e-05 | 37 | 0.001219 | 8 | Q_MOTIF | expasy.org/pros... |
Null PS00178 | View Gene Set | 2.018e-05 | 15 | 0.001648 | 9 | AA_TRNA_LIGASE_I | expasy.org/pros... |
Null PS00674 | View Gene Set | 3.015e-05 | 29 | 0.002073 | 10 | AAA | expasy.org/pros... |
Null PS00750 | View Gene Set | 3.666e-05 | 9 | 0.002073 | 10 | TCP1_1 | expasy.org/pros... |
Null PS00751 | View Gene Set | 3.666e-05 | 9 | 0.002073 | 10 | TCP1_2 | expasy.org/pros... |
Null PS00995 | View Gene Set | 3.666e-05 | 9 | 0.002073 | 10 | TCP1_3 | expasy.org/pros... |
Null PS50293 | View Gene Set | 7.058e-05 | 134 | 0.003705 | 14 | TPR_REGION | expasy.org/pros... |
Null PS00299 | View Gene Set | 0.0001289 | 10 | 0.006315 | 15 | UBIQUITIN_1 | expasy.org/pros... |
Null PS00039 | View Gene Set | 0.000243 | 27 | 0.008505 | 16 | DEAD_ATP_HELICASE | expasy.org/pros... |
Null PS00847 | View Gene Set | 0.0001973 | 6 | 0.008505 | 16 | MCM_1 | expasy.org/pros... |
Null PS50005 | View Gene Set | 0.0002301 | 114 | 0.008505 | 16 | TPR | expasy.org/pros... |
Null PS50053 | View Gene Set | 0.0002204 | 58 | 0.008505 | 16 | UBIQUITIN_2 | expasy.org/pros... |
Null PS50082 | View Gene Set | 0.0002234 | 233 | 0.008505 | 16 | WD_REPEATS_2 | expasy.org/pros... |
Null PS50166 | View Gene Set | 0.0002376 | 13 | 0.008505 | 16 | IMPORTIN_B_NT | expasy.org/pros... |
Null PS50072 | View Gene Set | 0.0002609 | 35 | 0.008715 | 22 | CSA_PPIASE_2 | expasy.org/pros... |
Null PS00170 | View Gene Set | 0.0002935 | 25 | 0.009378 | 23 | CSA_PPIASE_1 | expasy.org/pros... |
Null PS00301 | View Gene Set | 0.0004057 | 11 | 0.01193 | 24 | EFACTOR_GTP | expasy.org/pros... |
Null PS50051 | View Gene Set | 0.0003925 | 8 | 0.01193 | 24 | MCM_2 | expasy.org/pros... |
Null PS50089 | View Gene Set | 0.0006138 | 301 | 0.01735 | 26 | ZF_RING_2 | expasy.org/pros... |
Null PS50920 | View Gene Set | 0.0008426 | 59 | 0.02294 | 27 | SOLCAR | expasy.org/pros... |
Null PS00125 | View Gene Set | 0.001004 | 13 | 0.02636 | 28 | SER_THR_PHOSPHATASE | expasy.org/pros... |
Null PS51151 | View Gene Set | 0.001157 | 9 | 0.02932 | 29 | NAC_AB | expasy.org/pros... |
Null PS50137 | View Gene Set | 0.001419 | 20 | 0.0298 | 30 | DS_RBD | expasy.org/pros... |
Null PS50294 | View Gene Set | 0.00134 | 245 | 0.0298 | 30 | WD_REPEATS_REGION | expasy.org/pros... |
Null PS50800 | View Gene Set | 0.00138 | 23 | 0.0298 | 30 | SAP | expasy.org/pros... |
Null PS50908 | View Gene Set | 0.001224 | 10 | 0.0298 | 30 | RWD | expasy.org/pros... |
Null PS51293 | View Gene Set | 0.001346 | 26 | 0.0298 | 30 | SANT | expasy.org/pros... |
Null PS51309 | View Gene Set | 0.001314 | 7 | 0.0298 | 30 | PABC | expasy.org/pros... |
Null PS00113 | View Gene Set | 0.001839 | 6 | 0.03747 | 36 | ADENYLATE_KINASE | expasy.org/pros... |
Null PS50867 | View Gene Set | 0.001886 | 7 | 0.03747 | 36 | PRE_SET | expasy.org/pros... |
Null PS00678 | View Gene Set | 0.001997 | 168 | 0.03862 | 38 | WD_REPEATS_1 | expasy.org/pros... |
Null PS01359 | View Gene Set | 0.002523 | 72 | 0.04523 | 39 | ZF_PHD_1 | expasy.org/pros... |
Null PS50866 | View Gene Set | 0.002459 | 19 | 0.04523 | 39 | GOLD | expasy.org/pros... |
Null PS50922 | View Gene Set | 0.002469 | 16 | 0.04523 | 39 | TLC | expasy.org/pros... |
Null PS00470 | View Gene Set | 0.00261 | 5 | 0.04545 | 42 | IDH_IMDH | expasy.org/pros... |
Null PS50103 | View Gene Set | 0.002887 | 60 | 0.04545 | 42 | ZF_C3H1 | expasy.org/pros... |
Null PS50171 | View Gene Set | 0.002774 | 9 | 0.04545 | 42 | ZF_MATRIN | expasy.org/pros... |
Null PS50296 | View Gene Set | 0.002906 | 6 | 0.04545 | 42 | SUI1 | expasy.org/pros... |
Null PS50862 | View Gene Set | 0.00285 | 18 | 0.04545 | 42 | AA_TRNA_LIGASE_II | expasy.org/pros... |
Null PS51038 | View Gene Set | 0.002774 | 11 | 0.04545 | 42 | BAH | expasy.org/pros... |
Null PS50969 | View Gene Set | 0.002968 | 8 | 0.04545 | 48 | FCP1 | expasy.org/pros... |
Null PS51316 | View Gene Set | 0.003132 | 19 | 0.04698 | 49 | NBPF | expasy.org/pros... |
Null PS51391 | View Gene Set | 0.003268 | 8 | 0.0471 | 50 | CID | expasy.org/pros... |
Null PS51419 | View Gene Set | 0.003225 | 83 | 0.0471 | 50 | RAB | expasy.org/pros... |
Null PS50255 | View Gene Set | 0.003496 | 11 | 0.04942 | 52 | CYTOCHROME_B5_2 | expasy.org/pros... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null EC:6.3.2.19 | View Gene Set | 6.058e-11 | 79 | 9.571e-09 | 1 | Ubiquitin--protein ligase | expasy.org/enzy... |
Null EC:1.6.99.3 | View Gene Set | 4.658e-06 | 35 | 0.0003366 | 2 | NADH dehydrogenase | expasy.org/enzy... |
Null EC:2.1.1.43 | View Gene Set | 6.392e-06 | 19 | 0.0003366 | 2 | Histone-lysine N-methyltransferase | expasy.org/enzy... |
Null EC:1.6.5.3 | View Gene Set | 9.642e-06 | 43 | 0.0003808 | 4 | NADH dehydrogenase (ubiquinone) | expasy.org/enzy... |
Null EC:2.7.11.1 | View Gene Set | 5.421e-05 | 91 | 0.001713 | 5 | Non-specific serine/threonine protein kinase | expasy.org/enzy... |
Null EC:1.10.2.2 | View Gene Set | 0.0001311 | 13 | 0.003453 | 6 | Ubiquinol--cytochrome-c reductase | expasy.org/enzy... |
Null EC:3.6.3.14 | View Gene Set | 0.0003753 | 45 | 0.00847 | 7 | H(+)-transporting two-sector ATPase | expasy.org/enzy... |
Null EC:3.4.25.1 | View Gene Set | 0.001471 | 20 | 0.02905 | 8 | Proteasome endopeptidase complex | expasy.org/enzy... |
Null EC:5.3.4.1 | View Gene Set | 0.001828 | 4 | 0.03208 | 9 | Protein disulfide-isomerase | expasy.org/enzy... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null ppi.CDKN1A | View Gene Set | 3.83e-05 | 9 | 0.004705 | 1 | Protein-protein-interaction for CDKN1A | www.ncbi.nlm.ni... |
Null ppi.E2F1 | View Gene Set | 8.156e-05 | 12 | 0.004705 | 1 | Protein-protein-interaction for E2F1 | www.ncbi.nlm.ni... |
Null ppi.ARHGAP8 | View Gene Set | 9.958e-05 | 8 | 0.004705 | 1 | Protein-protein-interaction for ARHGAP8 | www.ncbi.nlm.ni... |
Null ppi.RB1 | View Gene Set | 7.276e-05 | 44 | 0.004705 | 1 | Protein-protein-interaction for RB1 | www.ncbi.nlm.ni... |
Null ppi.1491938 | View Gene Set | 0.0002096 | 25 | 0.004951 | 5 | Protein-protein-interaction for 1491938 | www.ncbi.nlm.ni... |
Null ppi.MYC | View Gene Set | 0.0002004 | 16 | 0.004951 | 5 | Protein-protein-interaction for MYC | www.ncbi.nlm.ni... |
Null ppi.RBL2 | View Gene Set | 0.0001925 | 14 | 0.004951 | 5 | Protein-protein-interaction for RBL2 | www.ncbi.nlm.ni... |
Null ppi.YY1 | View Gene Set | 0.0001768 | 9 | 0.004951 | 5 | Protein-protein-interaction for YY1 | www.ncbi.nlm.ni... |
Null ppi.E2F4 | View Gene Set | 0.0003317 | 14 | 0.006269 | 9 | Protein-protein-interaction for E2F4 | www.ncbi.nlm.ni... |
Null ppi.UXT | View Gene Set | 0.0003236 | 8 | 0.006269 | 9 | Protein-protein-interaction for UXT | www.ncbi.nlm.ni... |
Null ppi.RIBIN | View Gene Set | 0.000435 | 8 | 0.007474 | 11 | Protein-protein-interaction for RIBIN | www.ncbi.nlm.ni... |
Null ppi.RNF11 | View Gene Set | 0.0006053 | 8 | 0.009533 | 12 | Protein-protein-interaction for RNF11 | www.ncbi.nlm.ni... |
Null ppi.RALBP1 | View Gene Set | 0.001418 | 7 | 0.01915 | 13 | Protein-protein-interaction for RALBP1 | www.ncbi.nlm.ni... |
Null ppi.MDM2 | View Gene Set | 0.001384 | 5 | 0.01915 | 13 | Protein-protein-interaction for MDM2 | www.ncbi.nlm.ni... |
Null ppi.GEMIN6 | View Gene Set | 0.001562 | 7 | 0.01968 | 15 | Protein-protein-interaction for GEMIN6 | www.ncbi.nlm.ni... |
Null ppi.PCNA | View Gene Set | 0.001893 | 11 | 0.02236 | 16 | Protein-protein-interaction for PCNA | www.ncbi.nlm.ni... |
Null ppi.NCF1C | View Gene Set | 0.002011 | 7 | 0.02236 | 16 | Protein-protein-interaction for NCF1C | www.ncbi.nlm.ni... |
Null ppi.155871 | View Gene Set | 0.00234 | 21 | 0.02328 | 18 | Protein-protein-interaction for 155871 | www.ncbi.nlm.ni... |
Null ppi.SNORD3A | View Gene Set | 0.002313 | 9 | 0.02328 | 18 | Protein-protein-interaction for SNORD3A | www.ncbi.nlm.ni... |
Null ppi.PAK1 | View Gene Set | 0.002702 | 7 | 0.02553 | 20 | Protein-protein-interaction for PAK1 | www.ncbi.nlm.ni... |
Null ppi.CCNA1 | View Gene Set | 0.003067 | 11 | 0.02657 | 21 | Protein-protein-interaction for CCNA1 | www.ncbi.nlm.ni... |
Null ppi.951475 | View Gene Set | 0.003093 | 43 | 0.02657 | 21 | Protein-protein-interaction for 951475 | www.ncbi.nlm.ni... |
Null ppi.PKP3 | View Gene Set | 0.004348 | 10 | 0.03044 | 23 | Protein-protein-interaction for PKP3 | www.ncbi.nlm.ni... |
Null ppi.COPS4 | View Gene Set | 0.004058 | 7 | 0.03044 | 23 | Protein-protein-interaction for COPS4 | www.ncbi.nlm.ni... |
Null ppi.PRNP | View Gene Set | 0.004015 | 7 | 0.03044 | 23 | Protein-protein-interaction for PRNP | www.ncbi.nlm.ni... |
Null ppi.MOAP1 | View Gene Set | 0.004099 | 7 | 0.03044 | 23 | Protein-protein-interaction for MOAP1 | www.ncbi.nlm.ni... |
Null ppi.XRCC5 | View Gene Set | 0.004313 | 8 | 0.03044 | 23 | Protein-protein-interaction for XRCC5 | www.ncbi.nlm.ni... |
Null ppi.BACE1 | View Gene Set | 0.004843 | 7 | 0.03269 | 28 | Protein-protein-interaction for BACE1 | www.ncbi.nlm.ni... |
Gene Set Name | GeneSetDescription | Value | Gene Set Size | Corrected Value | Ranking | Description | URL |
---|---|---|---|---|---|---|---|
Null ppi.155871 | View Gene Set | 3.047e-36 | 236 | 7e-33 | 1 | Protein-protein-interaction for 155871 | www.ncbi.nlm.ni... |
Null ppi.MEPCE | View Gene Set | 1.323e-32 | 147 | 1.519e-29 | 2 | Protein-protein-interaction for MEPCE | www.ncbi.nlm.ni... |
Null ppi.SRRM2 | View Gene Set | 2.256e-19 | 101 | 1.727e-16 | 3 | Protein-protein-interaction for SRRM2 | www.ncbi.nlm.ni... |
Null ppi.KHDRBS2 | View Gene Set | 1.161e-14 | 46 | 6.669e-12 | 4 | Protein-protein-interaction for KHDRBS2 | www.ncbi.nlm.ni... |
Null ppi.TP53 | View Gene Set | 4.699e-14 | 168 | 2.159e-11 | 5 | Protein-protein-interaction for TP53 | www.ncbi.nlm.ni... |
Null ppi.72462 | View Gene Set | 2.329e-13 | 42 | 8.915e-11 | 6 | Protein-protein-interaction for 72462 | www.ncbi.nlm.ni... |
Null ppi.SRRM1 | View Gene Set | 5.108e-13 | 64 | 1.676e-10 | 7 | Protein-protein-interaction for SRRM1 | www.ncbi.nlm.ni... |
Null ppi.RUVBL2 | View Gene Set | 9.733e-12 | 64 | 2.794e-09 | 8 | Protein-protein-interaction for RUVBL2 | www.ncbi.nlm.ni... |
Null ppi.DDA1 | View Gene Set | 4.864e-11 | 44 | 1.241e-08 | 9 | Protein-protein-interaction for DDA1 | www.ncbi.nlm.ni... |
Null ppi.GSTK1 | View Gene Set | 1.776e-10 | 26 | 4.081e-08 | 10 | Protein-protein-interaction for GSTK1 | www.ncbi.nlm.ni... |
Null ppi.TOPORS | View Gene Set | 3.257e-10 | 27 | 6.801e-08 | 11 | Protein-protein-interaction for TOPORS | www.ncbi.nlm.ni... |
Null ppi.SUMO2 | View Gene Set | 2.054e-09 | 50 | 3.931e-07 | 12 | Protein-protein-interaction for SUMO2 | www.ncbi.nlm.ni... |
Null ppi.GPN1 | View Gene Set | 5.823e-09 | 27 | 1.029e-06 | 13 | Protein-protein-interaction for GPN1 | www.ncbi.nlm.ni... |
Null ppi.TCERG1 | View Gene Set | 7.73e-09 | 35 | 1.184e-06 | 14 | Protein-protein-interaction for TCERG1 | www.ncbi.nlm.ni... |
Null ppi.WBP4 | View Gene Set | 7.401e-09 | 35 | 1.184e-06 | 14 | Protein-protein-interaction for WBP4 | www.ncbi.nlm.ni... |
Null ppi.RNPS1 | View Gene Set | 8.327e-09 | 38 | 1.195e-06 | 16 | Protein-protein-interaction for RNPS1 | www.ncbi.nlm.ni... |
Null ppi.CDT1 | View Gene Set | 1.346e-08 | 37 | 1.818e-06 | 17 | Protein-protein-interaction for CDT1 | www.ncbi.nlm.ni... |
Null ppi.UCHL5 | View Gene Set | 1.916e-08 | 33 | 2.41e-06 | 18 | Protein-protein-interaction for UCHL5 | www.ncbi.nlm.ni... |
Null ppi.RUVBL1 | View Gene Set | 1.993e-08 | 38 | 2.41e-06 | 18 | Protein-protein-interaction for RUVBL1 | www.ncbi.nlm.ni... |
Null ppi.EIF1B | View Gene Set | 2.3e-08 | 25 | 2.641e-06 | 20 | Protein-protein-interaction for EIF1B | www.ncbi.nlm.ni... |
Null ppi.TH1L | View Gene Set | 3.043e-08 | 26 | 3.177e-06 | 21 | Protein-protein-interaction for TH1L | www.ncbi.nlm.ni... |
Null ppi.UBA5 | View Gene Set | 2.908e-08 | 35 | 3.177e-06 | 21 | Protein-protein-interaction for UBA5 | www.ncbi.nlm.ni... |
Null ppi.BANF1 | View Gene Set | 3.388e-08 | 34 | 3.384e-06 | 23 | Protein-protein-interaction for BANF1 | www.ncbi.nlm.ni... |
Null ppi.EIF3F | View Gene Set | 3.692e-08 | 22 | 3.534e-06 | 24 | Protein-protein-interaction for EIF3F | www.ncbi.nlm.ni... |
Null ppi.PRPF40A | View Gene Set | 4.085e-08 | 53 | 3.753e-06 | 25 | Protein-protein-interaction for PRPF40A | www.ncbi.nlm.ni... |
Null ppi.DDX56 | View Gene Set | 5.904e-08 | 20 | 5.216e-06 | 26 | Protein-protein-interaction for DDX56 | www.ncbi.nlm.ni... |
Null ppi.LYAR | View Gene Set | 7.65e-08 | 26 | 6.508e-06 | 27 | Protein-protein-interaction for LYAR | www.ncbi.nlm.ni... |
Null ppi.DDX20 | View Gene Set | 8.852e-08 | 17 | 7.262e-06 | 28 | Protein-protein-interaction for DDX20 | www.ncbi.nlm.ni... |
Null ppi.KIAA1377 | View Gene Set | 9.669e-08 | 57 | 7.659e-06 | 29 | Protein-protein-interaction for KIAA1377 | www.ncbi.nlm.ni... |
Null ppi.MGMT | View Gene Set | 1.407e-07 | 28 | 1.077e-05 | 30 | Protein-protein-interaction for MGMT | www.ncbi.nlm.ni... |
Null ppi.RRP1B | View Gene Set | 1.752e-07 | 21 | 1.298e-05 | 31 | Protein-protein-interaction for RRP1B | www.ncbi.nlm.ni... |
Null ppi.STRN3 | View Gene Set | 2.952e-07 | 22 | 2.119e-05 | 32 | Protein-protein-interaction for STRN3 | www.ncbi.nlm.ni... |
Null ppi.MYC | View Gene Set | 3.064e-07 | 42 | 2.133e-05 | 33 | Protein-protein-interaction for MYC | www.ncbi.nlm.ni... |
Null ppi.PABPC1 | View Gene Set | 3.822e-07 | 26 | 2.582e-05 | 34 | Protein-protein-interaction for PABPC1 | www.ncbi.nlm.ni... |
Null ppi.PAAF1 | View Gene Set | 4.056e-07 | 20 | 2.623e-05 | 35 | Protein-protein-interaction for PAAF1 | www.ncbi.nlm.ni... |
Null ppi.HIST1H4A | View Gene Set | 4.111e-07 | 28 | 2.623e-05 | 35 | Protein-protein-interaction for HIST1H4A | www.ncbi.nlm.ni... |
Null ppi.CBX5 | View Gene Set | 4.8e-07 | 38 | 2.902e-05 | 37 | Protein-protein-interaction for CBX5 | www.ncbi.nlm.ni... |
Null ppi.SIN3A | View Gene Set | 4.68e-07 | 104 | 2.902e-05 | 37 | Protein-protein-interaction for SIN3A | www.ncbi.nlm.ni... |
Null ppi.MTA2 | View Gene Set | 4.941e-07 | 25 | 2.91e-05 | 39 | Protein-protein-interaction for MTA2 | www.ncbi.nlm.ni... |
Null ppi.COPS6 | View Gene Set | 6.692e-07 | 65 | 3.749e-05 | 40 | Protein-protein-interaction for COPS6 | www.ncbi.nlm.ni... |
Null ppi.ZMYM2 | View Gene Set | 6.567e-07 | 14 | 3.749e-05 | 40 | Protein-protein-interaction for ZMYM2 | www.ncbi.nlm.ni... |
Null ppi.BRF2 | View Gene Set | 7.404e-07 | 23 | 4.049e-05 | 42 | Protein-protein-interaction for BRF2 | www.ncbi.nlm.ni... |
Null ppi.UIMC1 | View Gene Set | 7.608e-07 | 30 | 4.064e-05 | 43 | Protein-protein-interaction for UIMC1 | www.ncbi.nlm.ni... |
Null ppi.PINX1 | View Gene Set | 1.067e-06 | 19 | 5.573e-05 | 44 | Protein-protein-interaction for PINX1 | www.ncbi.nlm.ni... |
Null ppi.RB1 | View Gene Set | 1.354e-06 | 46 | 6.91e-05 | 45 | Protein-protein-interaction for RB1 | www.ncbi.nlm.ni... |
Null ppi.MBD2 | View Gene Set | 1.384e-06 | 11 | 6.913e-05 | 46 | Protein-protein-interaction for MBD2 | www.ncbi.nlm.ni... |
Null ppi.BRCC3 | View Gene Set | 1.574e-06 | 22 | 7.694e-05 | 47 | Protein-protein-interaction for BRCC3 | www.ncbi.nlm.ni... |
Null ppi.WDR48 | View Gene Set | 1.623e-06 | 52 | 7.768e-05 | 48 | Protein-protein-interaction for WDR48 | www.ncbi.nlm.ni... |
Null ppi.CNBP | View Gene Set | 1.83e-06 | 17 | 8.578e-05 | 49 | Protein-protein-interaction for CNBP | www.ncbi.nlm.ni... |
Null ppi.DZIP3 | View Gene Set | 2.731e-06 | 18 | 0.0001255 | 50 | Protein-protein-interaction for DZIP3 | www.ncbi.nlm.ni... |
Null ppi.VHL | View Gene Set | 2.788e-06 | 50 | 0.0001256 | 51 | Protein-protein-interaction for VHL | www.ncbi.nlm.ni... |
Null ppi.SAP25 | View Gene Set | 3.19e-06 | 29 | 0.0001409 | 52 | Protein-protein-interaction for SAP25 | www.ncbi.nlm.ni... |
Null ppi.CHFR | View Gene Set | 4.317e-06 | 18 | 0.0001871 | 53 | Protein-protein-interaction for CHFR | www.ncbi.nlm.ni... |
Null ppi.SMARCA2 | View Gene Set | 4.484e-06 | 29 | 0.0001907 | 54 | Protein-protein-interaction for SMARCA2 | www.ncbi.nlm.ni... |
Null ppi.USP14 | View Gene Set | 5.079e-06 | 22 | 0.0002121 | 55 | Protein-protein-interaction for USP14 | www.ncbi.nlm.ni... |
Null ppi.MKRN3 | View Gene Set | 5.277e-06 | 14 | 0.0002165 | 56 | Protein-protein-interaction for MKRN3 | www.ncbi.nlm.ni... |
Null ppi.RPAP1 | View Gene Set | 5.815e-06 | 24 | 0.0002343 | 57 | Protein-protein-interaction for RPAP1 | www.ncbi.nlm.ni... |
Null ppi.AKTIP | View Gene Set | 6.295e-06 | 21 | 0.0002493 | 58 | Protein-protein-interaction for AKTIP | www.ncbi.nlm.ni... |
Null ppi.MOBKL3 | View Gene Set | 6.476e-06 | 34 | 0.0002521 | 59 | Protein-protein-interaction for MOBKL3 | www.ncbi.nlm.ni... |
Null ppi.XRN1 | View Gene Set | 7.074e-06 | 12 | 0.0002708 | 60 | Protein-protein-interaction for XRN1 | www.ncbi.nlm.ni... |
Null ppi.PSMD6 | View Gene Set | 7.667e-06 | 21 | 0.0002887 | 61 | Protein-protein-interaction for PSMD6 | www.ncbi.nlm.ni... |
Null ppi.WDR8 | View Gene Set | 8.131e-06 | 23 | 0.0003012 | 62 | Protein-protein-interaction for WDR8 | www.ncbi.nlm.ni... |
Null ppi.KAT5 | View Gene Set | 8.408e-06 | 51 | 0.0003066 | 63 | Protein-protein-interaction for KAT5 | www.ncbi.nlm.ni... |
Null ppi.EIF3B | View Gene Set | 9.341e-06 | 10 | 0.0003353 | 64 | Protein-protein-interaction for EIF3B | www.ncbi.nlm.ni... |
Null ppi.UBE2I | View Gene Set | 1.037e-05 | 62 | 0.000365 | 65 | Protein-protein-interaction for UBE2I | www.ncbi.nlm.ni... |
Null ppi.EIF3A | View Gene Set | 1.049e-05 | 12 | 0.000365 | 65 | Protein-protein-interaction for EIF3A | www.ncbi.nlm.ni... |
Null ppi.HDAC2 | View Gene Set | 1.159e-05 | 34 | 0.0003938 | 67 | Protein-protein-interaction for HDAC2 | www.ncbi.nlm.ni... |
Null ppi.NPM1 | View Gene Set | 1.166e-05 | 16 | 0.0003938 | 67 | Protein-protein-interaction for NPM1 | www.ncbi.nlm.ni... |
Null ppi.RCOR1 | View Gene Set | 1.193e-05 | 21 | 0.0003973 | 69 | Protein-protein-interaction for RCOR1 | www.ncbi.nlm.ni... |
Null ppi.ORC2L | View Gene Set | 1.269e-05 | 12 | 0.0004164 | 70 | Protein-protein-interaction for ORC2L | www.ncbi.nlm.ni... |
Null ppi.TRIM5 | View Gene Set | 1.487e-05 | 14 | 0.0004811 | 71 | Protein-protein-interaction for TRIM5 | www.ncbi.nlm.ni... |
Null ppi.PSMD13 | View Gene Set | 1.653e-05 | 20 | 0.0005229 | 72 | Protein-protein-interaction for PSMD13 | www.ncbi.nlm.ni... |
Null ppi.TRIB3 | View Gene Set | 1.662e-05 | 24 | 0.0005229 | 72 | Protein-protein-interaction for TRIB3 | www.ncbi.nlm.ni... |
Null ppi.HNRNPR | View Gene Set | 1.868e-05 | 9 | 0.0005799 | 74 | Protein-protein-interaction for HNRNPR | www.ncbi.nlm.ni... |
Null ppi.HIST3H3 | View Gene Set | 1.936e-05 | 16 | 0.000593 | 75 | Protein-protein-interaction for HIST3H3 | www.ncbi.nlm.ni... |
Null ppi.PSMD14 | View Gene Set | 2.133e-05 | 16 | 0.0006363 | 76 | Protein-protein-interaction for PSMD14 | www.ncbi.nlm.ni... |
Null ppi.SP1 | View Gene Set | 2.115e-05 | 79 | 0.0006363 | 76 | Protein-protein-interaction for SP1 | www.ncbi.nlm.ni... |
Null ppi.SSRP1 | View Gene Set | 2.199e-05 | 15 | 0.0006475 | 78 | Protein-protein-interaction for SSRP1 | www.ncbi.nlm.ni... |
Null ppi.YY1 | View Gene Set | 2.267e-05 | 34 | 0.0006593 | 79 | Protein-protein-interaction for YY1 | www.ncbi.nlm.ni... |
Null ppi.EEF1G | View Gene Set | 2.373e-05 | 9 | 0.0006809 | 80 | Protein-protein-interaction for EEF1G | www.ncbi.nlm.ni... |
Null ppi.ARFIP2 | View Gene Set | 2.46e-05 | 9 | 0.0006809 | 80 | Protein-protein-interaction for ARFIP2 | www.ncbi.nlm.ni... |
Null ppi.C12orf44 | View Gene Set | 2.445e-05 | 32 | 0.0006809 | 80 | Protein-protein-interaction for C12orf44 | www.ncbi.nlm.ni... |
Null ppi.XRCC5 | View Gene Set | 2.461e-05 | 40 | 0.0006809 | 80 | Protein-protein-interaction for XRCC5 | www.ncbi.nlm.ni... |
Null ppi.CARM1 | View Gene Set | 2.612e-05 | 32 | 0.0007059 | 84 | Protein-protein-interaction for CARM1 | www.ncbi.nlm.ni... |
Null ppi.BRE | View Gene Set | 2.6e-05 | 16 | 0.0007059 | 84 | Protein-protein-interaction for BRE | www.ncbi.nlm.ni... |
Null ppi.C1orf103 | View Gene Set | 2.762e-05 | 95 | 0.0007377 | 86 | Protein-protein-interaction for C1orf103 | www.ncbi.nlm.ni... |
Null ppi.IKBKE | View Gene Set | 2.807e-05 | 19 | 0.0007411 | 87 | Protein-protein-interaction for IKBKE | www.ncbi.nlm.ni... |
Null ppi.MTA1 | View Gene Set | 2.844e-05 | 21 | 0.0007424 | 88 | Protein-protein-interaction for MTA1 | www.ncbi.nlm.ni... |
Null ppi.SF3B1 | View Gene Set | 2.901e-05 | 24 | 0.0007483 | 89 | Protein-protein-interaction for SF3B1 | www.ncbi.nlm.ni... |
Null ppi.HDAC1 | View Gene Set | 2.932e-05 | 67 | 0.0007483 | 89 | Protein-protein-interaction for HDAC1 | www.ncbi.nlm.ni... |
Null ppi.THRA | View Gene Set | 3.054e-05 | 16 | 0.0007624 | 91 | Protein-protein-interaction for THRA | www.ncbi.nlm.ni... |
Null ppi.GIYD2 | View Gene Set | 3.024e-05 | 32 | 0.0007624 | 91 | Protein-protein-interaction for GIYD2 | www.ncbi.nlm.ni... |
Null ppi.C19orf62 | View Gene Set | 3.219e-05 | 29 | 0.0007867 | 93 | Protein-protein-interaction for C19orf62 | www.ncbi.nlm.ni... |
Null ppi.HDAC3 | View Gene Set | 3.208e-05 | 92 | 0.0007867 | 93 | Protein-protein-interaction for HDAC3 | www.ncbi.nlm.ni... |
Null ppi.TMBIM4 | View Gene Set | 3.579e-05 | 9 | 0.0008304 | 95 | Protein-protein-interaction for TMBIM4 | www.ncbi.nlm.ni... |
Null ppi.RNF111 | View Gene Set | 3.527e-05 | 20 | 0.0008304 | 95 | Protein-protein-interaction for RNF111 | www.ncbi.nlm.ni... |
Null ppi.C20orf24 | View Gene Set | 3.503e-05 | 20 | 0.0008304 | 95 | Protein-protein-interaction for C20orf24 | www.ncbi.nlm.ni... |
Null ppi.DDX24 | View Gene Set | 3.566e-05 | 20 | 0.0008304 | 95 | Protein-protein-interaction for DDX24 | www.ncbi.nlm.ni... |
Null ppi.SF3A2 | View Gene Set | 3.457e-05 | 16 | 0.0008304 | 95 | Protein-protein-interaction for SF3A2 | www.ncbi.nlm.ni... |
Null ppi.PDCD4 | View Gene Set | 3.786e-05 | 10 | 0.0008697 | 100 | Protein-protein-interaction for PDCD4 | www.ncbi.nlm.ni... |
Null ppi.RNU12-2P | View Gene Set | 3.905e-05 | 18 | 0.0008793 | 101 | Protein-protein-interaction for RNU12-2P | www.ncbi.nlm.ni... |
Null ppi.RNU11 | View Gene Set | 3.905e-05 | 18 | 0.0008793 | 101 | Protein-protein-interaction for RNU11 | www.ncbi.nlm.ni... |
Null ppi.MCM7 | View Gene Set | 3.943e-05 | 11 | 0.0008793 | 101 | Protein-protein-interaction for MCM7 | www.ncbi.nlm.ni... |
Null ppi.RFWD2 | View Gene Set | 4.51e-05 | 26 | 0.0009961 | 104 | Protein-protein-interaction for RFWD2 | www.ncbi.nlm.ni... |
Null ppi.STIP1 | View Gene Set | 4.65e-05 | 12 | 0.001017 | 105 | Protein-protein-interaction for STIP1 | w |